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Fumed silica, hydrophilic, specific surface area: 100 m2/g
Fumed silica is a fine and special amorphous silica product obtained by high-temperature hydrolysis of halosilane through oxyhydrogen flame. The primary particle size of the product is between 7-40nm, and the specific surface area is generally 100m2/g. Within the range of ~400m2/g, the product has high purity and SiO2 content of not less than 99.8%. It is an extremely important inorganic nano-powder material. Due to its superior stability, reinforcement, thickening and thixotropy, it has been widely used in rubber, plastics, electronics, coatings, medicine, agriculture and CMP. Uses: ·widely used in various coatings, plastics, adhesives and sealants, as reinforcement in rubber ·used in electronic packaging, ultra-large integrated circuits, advanced ceramics, ink industry ·manufacture of glass ceramics, abrasives, decolorization of oils ·purification of ferrosilicon, analytical determination of boron, arsenic and silver, etc. Group: Colloidal silica. CAS No. 112945-52-5. Mole weight: 60.09 g/mol. Appearance: Powder. Purity: 0.998. Density: 2.6 g/cm3. Catalog: ACM112945525-5.
Fumitremorgin c
Fumitremorgin C is a potent and selective ABCG2/BRCP inhibitor. Group: Inhibitors. Alternative Names: 12α-Fumitremorgin C. CAS No. 118974-02-0. Molecular formula: C22H25N3O3. Mole weight: 379.5. Appearance: Solid. Purity: 95%+. Canonical SMILES: O=C ([C@]1 ([H])CC2=C ([C@H] (/C=C (C)\C)N13)NC4=C2C=CC (OC)=C4)N5[C@] (CCC5) ([H])C3=O. Catalog: ACM118974020.
FUN06487
FUN06487, also known as SCD1 inhibitor-3, is a SCD1 inhibitor. This compound was first reported in WO 2011039358. Group: Inhibitors. Alternative Names: SCD1 inhibitor-3; FUN06487; FUN-06487; FUN 06487. CAS No. 1282606-48-7. Molecular formula: C19H16FN7O2. Mole weight: 393.38. Appearance: Solid powder. Purity: >98%. IUPACName: 5-(1-(4-fluorobenzyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)-N-(pyridin-3-ylmethyl)-1H-pyrazole-3-carboxamide. Canonical SMILES: O=C (C1=NNC (N2C=NN (CC3=CC=C (F)C=C3)C2=O)=C1)NCC4=CC=CN=C4. Catalog: ACM1282606487.
Heterocyclic Organic Compound. Alternative Names: BLUE 220;3-(4-Diethylamino-2-methylphenyl)-3-(1-ethyl-2-methyl-1H-indol-3-yl)-4-azaphthalide;3-[4-(Diethylamino)-2-methylphenyl]-3-(1-ethyl-2-methyl-1H-indole-3-yl)-4-azaphthalide;7-[4-(Diethylamino)-2-methylphenyl]-7-(1-ethyl-2-methyl-1H-indol-3-yl)furo. CAS No. 114090-18-5. Molecular formula: C29H31N3O2. Catalog: ACM114090185.
Furowanin A
Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells. Group: Inhibitors. CAS No. 911004-72-3. Molecular formula: C25H26O7. Mole weight: 438.5. Appearance: Powder. Purity: 0.98. IUPACName: 6-(3,4-dihydroxyphenyl)-4-hydroxy-2-(2-hydroxypropan-2-yl)-9-(3-methylbut-2-enyl)-2,3-dihydrofuro[3,2-g]chromen-5-one. Canonical SMILES: CC (=CCC1=C2C (=C (C3=C1OC=C (C3=O)C4=CC (=C (C=C4)O)O)O)CC (O2)C (C) (C)O)C. Catalog: ACM911004723.
Gadolinium Arsenide is a crystalline solid used as a semiconductor and in photo optic applications. Group: Heterocyclic organic compound. Alternative Names: Gadolinium arsenide, Gadolinium arsenide (GdAs), CID82780, EINECS 234-475-2, 12005-89-9. CAS No. 12005-89-9. Molecular formula: GdAs. Mole weight: 232g/mol. Appearance: solid. Purity: 0.96. IUPACName: arsanylidynegadolinium. Canonical SMILES: [As]#[Gd]. ECNumber: 234-475-2. Catalog: ACM12005899.
Gadolinium boride
Praseodymium Boride is generally immediately available in most volumes. HHigh purity, submicron and nanopowder forms may be considered. Group: Metal & ceramic materials. Alternative Names: Gadolinium boride;12008-06-9;GADOLINIUM BORIDE, GdB6; CTK8F9979; MFCD00049942; gadolinium(2+) pentacyclo[3.1.0.0^{1, 3}.0^{2, 4}.0^{4, 6}]hexaborane-1, 4-diuide. CAS No. 12008-06-9. Molecular formula: GdB6. Mole weight: 168.061 g/mol. Appearance: Black powder. IUPACName: gadolinium(2+);2, 3, 5, 6-tetrabora-1, 4-diboranuidapentacyclo[3.1.0.01, 3.02, 4.04, 6]hexane. Canonical SMILES: B12B3[B-]14B5[B-]23B45.[Gd+2]. Density: 5.27g/mL. ECNumber: 234-530-0. Catalog: ACM12008069.
Gadolinium Nitrate
Gadolinium Yttrium Garnet (Gd:Y3Al5O12); it has microwave applications and is used in fabrication of various optical components and as substrate material for magneto-optical films. Uses: Gadolinium nitrate is used for making optical glass and dopant for gadolinium yttrium garnets which have microwave applications, also applied in special catalyst and phosphors. gadolinium nitrate is also used for making green phosphors for color tv tubes. it is used in many quality assurance applications, such as line sources and calibration phantoms. Group: Heterocyclic organic compound. Alternative Names: GADOLINIUM NITRATE;GADOLINIUM NITRATE. CAS No. 94219-55-3. Molecular formula: Gd(NO3)3.xH2O. Mole weight: 343g/mol. Appearance: White crystalline. Density: 2.3g/mL. Catalog: ACM94219553.
Gadolinium Oxide
Heterocyclic Organic Compound. Alternative Names: Gadolinium(?) oxide;GADOLINIUM SESQUIOXIDE,99.9% Ф10MM. CAS No. 11129-31-0. Molecular formula: Gd2O3. Mole weight: 362.5. Catalog: ACM11129310.
Gadolinium Oxysulfide, Terbium-doped
Terbium doped Gadolinium Oxysulfide (Gadolinium Oxide Sulfide) is a phosphor material with applications in X-ray intensifying screens, ceramic scintillators, flat panel detectors, X-ray tomography, with an optical transmission range of 382-622 nm. Uses: Terbium doped gadolinium oxysulfide (gadolinium oxide sulfide) is a phosphor material with applications in x-ray intensifying screens, ceramic scintillators, flat panel detectors, x-ray tomography, with an optical transmission range of 382-622 nm. Group: Phosphors. Alternative Names: Tb-doped Gadolinium oxide sulfide(Gd2O2S), Gadolinium Oxysulfide:Tb, Gadolinium oxysulphide Tb doped, Tb:Gd2O2S. CAS No. 68609-43-8. Molecular formula: Gd2O2S:Tb. Mole weight: 537.49g/mol. Appearance: White powder. Density: 7.32g/mL. Catalog: ACM68609438-1.
Gadolinium Phosphide
Gadolinium Phosphide is a semiconductor used in hHigh power, hHigh frequency applications and in laser diodes. Group: Heterocyclic organic compound. CAS No. 12024-79-2. Molecular formula: GdP. Mole weight: 188g/mol. Appearance: solid. Catalog: ACM12024792.
Gadolinium Selenide
Gadolinium Selenide is generally immediately available in most volumes. HHigh purity, submicron and nanopowder forms may be considered. Group: Heterocyclic organic compound. Alternative Names: Gadolinium selenide, Gadolinium selenide (Gd2Se3), EINECS 234-700-4, CID165988, 12024-90-7. CAS No. 12024-90-7. Molecular formula: Gd2Se3. Mole weight: 551g/mol. Appearance: Crystalline. Purity: 0.96. IUPACName: gadolinium(3+); selenium(2-). Canonical SMILES: [Se-2].[Se-2].[Se-2].[Gd+3].[Gd+3]. ECNumber: 234-700-4. Catalog: ACM12024907.
Gadolinium Zirconate
Gadolinium Zirconate is an oxide-based ceramic with low thermal conductivity typically used as a thermal barrier coating. Group: Gd. CAS No. 11073-79-3. Molecular formula: Gd2O3 ZrO2. Mole weight: 609g/mol. Appearance: Solid. Density: 6.32g/mL. Catalog: ACM11073793.
gadoteridol Related Comp
Heterocyclic Organic Compound. CAS No. 112188-16-6. Catalog: ACM112188166.
Galactoarabinan
Natural, multifunctional polysaccharide (polymeric sugar called Arabinogalactan) obtained from the Eastern Larch Tree (larex larcinia) heartwood from trees which are grown in the United States. Offers multiple functional benefits for skin care and sun care products. Composed of 90-100% Galactoarabinan and 5-10% of water. Molecular weight 20,000 Daltons. Viscosity in 5% water: 5.0 CPS. Uses: Anti-wrinkle & anti-aging moisturizing lotions, creams, & serums. sun care products, makeup products & other color cosmetics. Group: Sugars and derivatives. Alternative Names: (+)-Arabinogalactan, Polyarabinogalactan. CAS No. 9036-66-2/7732-18-5. Molecular formula: C20H36O14. Mole weight: 500.49. Appearance: Off-white to tan powder, slightly aromatic. Purity: 0.98. IUPACName: 4-[6-[(3,5-Dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol. Canonical SMILES: CC1C (C (C (C (O1)CO)O)OC2C (C (C (C (O2)COC3C (C (C (CO3)O)OC)O)O)OC)O)O. Catalog: BBC9036662.
BETZ 0276 is a trihydroxybenzoic acid, a type of phenolic acid, a type of organic acid, also known as 3,4,5-trihydroxybenzoic acid, found in gallnuts, sumac, witch hazel, tea leaves, oak bark, and other plants. The chemical formula is C6H2(OH)3COOH. BETZ 0276 is found both free and as part of hydrolyzable tannins. The BETZ 0276 groups are usually bonded to form dimers such as ellagic acid. Hydrolyzable tannins break down on hydrolysis to give BETZ 0276 and glucose or ellagic acid and glucose, known as gallotannins and ellagitannins respectively.BETZ 0276 forms intermolecular esters (depsides) such as digallic and triBETZ 0276, and cyclic ether-esters (depsidones). Alternative Names: Graphite oxide. CAS No. 149-91-7. Molecular formula: C7H6O5. Mole weight: 170.12. Appearance: Off-white powder. Purity: 0.99. IUPACName: 3,4,5-Trihydroxybenzoic acid. Canonical SMILES: C1=C(C=C(C(=C1O)O)O)C(=O)O. Density: 1.694 g/cm³. ECNumber: 205-749-9. Catalog: ACM149917.
Gallium arsenide
Gallium arsenide appears as dark gray crystals with a metallic greenish-blue sheen or gray powder. Melting point 85.6°F (29.78°C).;Dark gray crystals with a metallic greenish-blue sheen or gray powder. Group: Electronic materialssubstrates and electrode materials. CAS No. 1303-00-0. Molecular formula: GaAs;GaAs;AsGa. Mole weight: 144.64g/mol. IUPACName: gallanylidynearsane. Canonical SMILES: [Ga]#[As]. Density: 5.31 at 77 °F (NTP, 1992);5.3176 @ 25 °C;5.31. ECNumber: 215-114-8. Catalog: ACM1303000.
Gallium Arsenide Phosphide (GaAsP)
GaAsP is a crystalline solid used as a semiconductor and in photo optic applications. Group: Semiconductor materials. Alternative Names: GaAsP; CAS 12044-20-1; digallium arsenide phosphide. CAS No. 210471-34-4. Molecular formula: GaAs1-xPx. Appearance: Solid. Purity: 99%|99.9%|99.99%|99.999%. Catalog: ACM210471344.
Gallium(III) 5-10-15-20-(tetraphenyl)porphyrin chloride (GaTPPCl) is an organometallic compound that is widely used in the scientific research community. It is a chlorinated porphyrin complex. Uses: Gallium(iII) 5-10-15-20-(tetraphenyl)porphyrin chloride is widely used in scientific research, particularly in the fields of photochemistry, biochemistry, and nanotechnology. in photochemistry, gallium(iII) 5-10-15-20-(tetraphenyl)porphyrin chloride is used as a photosensitizer in the synthesis of other organometallic compounds, such as gallium(iII) 5-10-15-20-tetraphenylporphyrinato-diethylenetri. Group: Porphyrins and phthalocyanines. CAS No. 78833-52-0. Molecular formula: C44H28ClGaN4. Mole weight: 717.91. Appearance: Purple solid. Purity: 0.98. IUPACName: 22-chloro-2, 7, 12, 17-tetraphenyl-21, 23, 24, 25-tetraza-22-gallahexacyclo[9.9.3.13, 6.113, 16.08, 23.018, 21]pentacosa-1(20), 2, 4, 6(25), 7, 9, 11, 13(24), 14, 16, 18-undecaene. Canonical SMILES: C1=CC=C (C=C1) C2=C3C=CC (=N3) C (=C4C=CC5=C (C6=NC (=C (C7=CC=C2N7[Ga] (N45) Cl) C8=CC=CC=C8) C=C6) C9=CC=CC=C9) C1=CC=CC=C1. Catalog: ACM78833520.
Gallium Nitride
Gallium nitride is a semiconductor that emits visible lHight (particularly blue and green). Uses: Bandgap semiconductor material, traffic signals, automotive interior lighting, led full-color displays, optical storage, led-generated indoor/outdoor lighting, laser diodes, underwater communications, high-resolution printings, full-color film printers, projection television, and biomedical uses, microwave radio-frequency power amplifiers, high-volume switching devices for power grids, and single-crystalline gallium nitride nanowires / tubes. Group: Metal & ceramic materials. Alternative Names: galliummononitride; galliumnitride(gan); GALLIUM NITRIDE;GALLIUM(III) NITRIDE;Gallium(III) nitride, 99.99+% metals basis;GALLIUM NITRIDEPOWDER; 99.99%(metalsbasis); Gallium Nitride, -100 Mesh. CAS No. 25617-97-4. Molecular formula: GaN. Mole weight: 83.7g/mol. Appearance: Yellowish to Dark Gray Powder. Purity: N/A. IUPACName: azanylidynegallane. Canonical SMILES: N#[Ga]. ECNumber: 247-129-0. Catalog: ACM25617974.
Other Alkaloids. Alternative Names: γ-Truxilline. CAS No. 113350-56-4. Mole weight: 658.8. Purity: 95%+. Catalog: ACM113350564.
Ganciclovir-d5
Ganciclovir-d5 is the deuterium labeled Ganciclovir. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1). Group: Inhibitors. Alternative Names: GANCICLOVIR-D5;2-Amino-1,9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]6H-purin-6-one-d5. CAS No. 1189966-73-1. Molecular formula: C9H13N5O4. Mole weight: 260.26. Appearance: White to Off-White Solid. Canonical SMILES: O=C1N=C (NC2=C1N=CN2COC ([2H]) (C ([2H]) (O)[2H])C ([2H]) (O)[2H])N. Catalog: ACM1189966731.
Ganciclovir sodium
Ganciclovir (BW 759) sodium, a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir sodium also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir sodium inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir sodium has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain. Group: Inhibitors. Alternative Names: GANCICLOVIR SODIUM;2-amino-1,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6h-purin-6-one sodium salt;9-[[1-(Hydroxymethyl)-2-hydroxyethoxy]methyl]-2-amino-9H-purine-6(1H)-one/sodium,(1:1) salt;Ganciclovir monosodium salt;6H-Purin-6-one, 1,9-dihydro-2-amino-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, monosodium salt;6H-Purin-6-one, 2-amino-1,9-dihydro-9-((2-hydroxy-1-(hydroxymethyl)ethoxy)methyl)-, monosodium salt;Rs 21592 sodium;Unii-02L083W284. CAS No. 107910-75-8. Molecular formula: C9H12N5NaO4. Mole weight: 277.21. Purity: 0.9985. Catalog: ACM107910758.
Total Ganglioside Extract (Brain, Porcine-Ammonium Salt). Group: Natural lipids. CAS No. 383907-71-9. Mole weight: 1563.853. Purity: >99%. Catalog: ACM383907719.
Ganoderic Acid A
Ganoderic acids are a class of closely related triterpenoids (derivatives from lanosterol) found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia. Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. There are dozens of ganoderic acids that have been isolated and characterized, of which ganoderic acid A and ganoderic acid B are the most well characterized. Some ganoderic acids have been found to possess biological activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition. (Source: http://en. wikipedia. org/wiki/Ganoderic_acid). Group: Others. Alternative Names: (25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid. CAS No. 81907-62-2. Molecular formula: C30H42O7. Mole weight: 514.65. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: C[C@H] (CC (=O)C[C@@H] (C)C (=O)O)[C@H]1C[C@@H] ([C@@]2 ([C@@]1 (CC (=O)C3=C2[C@H] (C[C@@H]4[C@@]3 (CCC (=O)C4 (C)C)C)O)C)C)O. Density: 1.22 g/ml. Catalog: ACM81907622.
Ganoderic Acid B
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease. Group: Inhibitors. CAS No. 81907-61-1. Molecular formula: C30H44O7. Mole weight: 516.7. Appearance: Powder. Purity: 0.98. IUPACName: (2R,6R)-6-[(3S,5R,7S,10S,13R,14R,17R)-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid. Canonical SMILES: CC (CC (=O)CC (C)C (=O)O)C1CC (=O)C2 (C1 (CC (=O)C3=C2C (CC4C3 (CCC (C4 (C)C)O)C)O)C)C. Catalog: ACM81907611.
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively. Group: Inhibitors. CAS No. 862893-75-2. Molecular formula: C30H44O4. Mole weight: 468.7. Appearance: Powder. Purity: 0.98. IUPACName: (E,6R)-6-[(10S,13R,14R,15S,17R)-15-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid. Canonical SMILES: CC (CCC=C (C)C (=O)O)C1CC (C2 (C1 (CC=C3C2=CCC4C3 (CCC (=O)C4 (C)C)C)C)C)O. Catalog: ACM862893752.
Ganoderic Acid X
Ganoderic acid X is a lanostanoid triterpene that can be extracted from Ganoderma amboinense. Ganoderic acid X inhibits topoisomerases and induces apoptosis of cancer cells. Group: Inhibitors. CAS No. 86377-53-9. Molecular formula: C32H48O5. Mole weight: 512.72. Appearance: Powder. Purity: 0.98. IUPACName: (E,6R)-6-[(3R,5R,10S,13R,14R,15S,17R)-15-acetyloxy-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid. Canonical SMILES: CC (CCC=C (C)C (=O)O)C1CC (C2 (C1 (CC=C3C2=CCC4C3 (CCC (C4 (C)C)O)C)C)C)OC (=O)C. Catalog: ACM86377539.
Ganoderic Acid Y
Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating. Group: Inhibitors. CAS No. 86377-52-8. Molecular formula: C30H46O3. Mole weight: 454.68. Appearance: Powder. Purity: 0.98. IUPACName: (E,6R)-6-[(3S,5R,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid. Canonical SMILES: CC (CCC=C (C)C (=O)O)C1CCC2 (C1 (CC=C3C2=CCC4C3 (CCC (C4 (C)C)O)C)C)C. Catalog: ACM86377528.
Ganoderol A is a terpenoid extracted from Ganoderma lucidum with antimicrobial activities. Ganoderol A inhibits cholesterol synthesis pathway and has significant anti-inflammatory activity and protection against ultraviolet A (UVA) damage. Group: Inhibitors. CAS No. 104700-97-2. Molecular formula: C30H46O2. Mole weight: 438.7. Appearance: Powder. Purity: 0.98. IUPACName: (10S,13R,14R,17S)-17-[(E,2R)-7-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one. Canonical SMILES: CC (CCC=C (C)CO)C1CCC2 (C1 (CC=C3C2=CCC4C3 (CCC (=O)C4 (C)C)C)C)C. Catalog: ACM104700972.
Ganoderone A
Ganoderone A is a triterpene compound that can be isolated from the fruiting body of Ganoderma pfeifferi and Ganoderma calidophilum. Ganoderone A has antiviral activity against HSV with IC50 value of 0.3 μg/mL. Ganoderone A has potential applications in viral infections and tumors. Group: Inhibitors. CAS No. 873061-79-1. Molecular formula: C30H46O3. Mole weight: 454.68. Appearance: Powder. Purity: 0.98. IUPACName: (5R,10S,13R,14R,17R)-17-[(E,2R)-7-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,7-dione. Canonical SMILES: CC (CCC=C (C)CO)C1CCC2 (C1 (CCC3=C2C (=O)CC4C3 (CCC (=O)C4 (C)C)C)C)C. Catalog: ACM873061791.
GANT61
GANT61 is a small-molecule inhibitor of glioma-associated oncogene 1 (GLI1)- and GLI2-mediated transcription at the nuclear level that exerts its effect by preventing DNA binding. It has been demonstrated to induce cell death against Ewing's sarcoma family tumor (ESFT) cell lines in a dose-dependent manner. Group: Inhibitors. Alternative Names: GANT61; GANT-61; GANT 61; NSC 136476. CAS No. 500579-04-4. Molecular formula: C27H35N5. Mole weight: 429.6. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2, 2'-((2-(pyridin-4-yl)dihydropyrimidine-1, 3(2H, 4H)-diyl)bis(methylene))bis(N, N-dimethylaniline). Canonical SMILES: CN (C)C1=CC=CC=C1CN2C (C3=CC=NC=C3)N (CC4=CC=CC=C4N (C)C)CCC2. Catalog: ACM500579044.
Gap 27
Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment. Group: Inhibitors. CAS No. 198284-64-9. Molecular formula: C60H101N15O17. Mole weight: 1304.55. Appearance: Solid. Purity: 0.9803. Catalog: ACM198284649.
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, while efficiently inhibiting the expression levels of cyclin B1, cyclin D1, cyclin E2, cdc2, Stat3 and CDK7. Garcinone C significantly inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time - and dose - dependent manner. Group: Inhibitors. Alternative Names: 1,3,6,7-Tetrahydroxy-8-(3-hydroxy-3-methylbutyl)-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one. CAS No. 76996-27-5. Molecular formula: C23H26O7. Mole weight: 414.45. Appearance: Powder. Purity: 0.98. IUPACName: 1,3,6,7-Tetrahydroxy-8-(3-hydroxy-3-methylbutyl)-2-(3-methylbut-2-enyl)xanthen-9-one. Canonical SMILES: CC (=CCC1=C (C2=C (C=C1O)OC3=C (C2=O)C (=C (C (=C3)O)O)CCC (C) (C)O)O)C. Density: 1.367 g/ml. Catalog: ACM76996275.
Extract obtained from Gardenia Florida (Gardenia) flowers. Contains 20% extract dissolved in water and glycerin. Has excellent soothing and calming properties. Uses: Ointments, salves, hair care products and lotions. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 92457-01-7 / 122-99-6. Appearance: Light to medium yellow to amber liquid, characteristic odor. Catalog: CI-SC-0936.
Gardiquimod TFA
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. The core structure is 1H-imidazo[4,5-c]quinoline, as found in related drugs such as imiquimod and resiquimod. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch. Group: Others. Alternative Names: Gardiquimod TFA salt; Gardiquimod. CAS No. 1159840-61-5. Molecular formula: C19H24F3N5O3. Mole weight: 427.43. Appearance: Solid powder. Purity: >98%. IUPACName: 1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol 2,2,2-trifluoroacetate. Canonical SMILES: CC (O) (C)CN1C (CNCC)=NC2=C1C3=CC=CC=C3N=C2N. O=C (O)C (F) (F)F. Catalog: ACM1159840615.
Garenoxacin
Garenoxacin (BMS284756) is an orally active quinolone antibiotic and has a broad spectrum of activity against a wide array of gram-positive and gram-negative bacteria, anaerobes, and fastidious organisms. Group: Inhibitors. Alternative Names: GARENOXACIN HBR;Garenoxacin;1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihydro-1H-isoindol-5-yl]-4-oxoquinoline-3-carboxylic acid;1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-(1-methyl-2,3-dihydro-1H-5-isoindolyl)-4-oxo-1,4-dihydro-3-quinolineca. CAS No. 194804-75-6. Molecular formula: C23H20F2N2O4. Mole weight: 426.41. Catalog: ACM194804756.
Gartanin
Gartanin is a natural xanthone of mangosteen, with antioxidant, anti-inflammatory, antifungal, neuroprotective and antineoplastic properties. Gartanin induces cell cycle arrest and autophagy and suppresses migration in human glioma cells. Group: Inhibitors. CAS No. 33390-42-0. Molecular formula: C23H24O6. Mole weight: 396.43. Appearance: Solid. Purity: 0.9993. Canonical SMILES: O=C1C2=C (OC3=C (O)C=CC (O)=C13)C (C/C=C (C)\C)=C (O)C (C/C=C (C)/C)=C2O. Catalog: ACM33390420.
GaTe Thin Film
We synthesized multilayer gallium telluride (GaTe) films using atomic layer deposition (ALD) growth to achieve large monodomain films with a negligible number of grain boundaries. Uses: Gate thin films are particularly suitable for thin film geometry measurements such as catalysis, photovoltaics, electron transport, etc. Group: 2d thin films. CAS No. 12024-14-5. Purity: Better than 99.9999% (6N). Catalog: ACM12024145-1.
Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo. Group: Inhibitors. Alternative Names: AKOS NCG1-0010;1-CYCLOPROPYL-6-FLUORO-8-METHOXY-7-(3-METHYL-PIPERAZIN-1-YL)-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-8-METHOXY-7-(3-METHYLPIPERAZIN-1-YL)-4-OXO-3-QUINOLINECARBOXYLIC ACID;1-CYCLOPROPYL-6-FLUORO-1,4-. CAS No. 180200-66-2. Molecular formula: C19H22FN3O4.1.5(H2O). Mole weight: 402.42. Appearance: Almost white to light yellow crystalline powder. Purity: 0.98. Density: 1.386 g/cm³. Catalog: ACM180200662.
Gboxin chloride
Gboxin chloride is an oxidative phosphorylation inhibitor that targets glioblastoma but not embryonic fibroblasts or neonatal astrocytes. Gboxin rapidly and irreversibly compromises oxygen consumption in glioblastoma cells. Gboxin relies on its positive charge to associate with mitochondrial oxidative phosphorylation complexes in a manner that is dependent on the proton gradient of the inner mitochondrial membrane, and it inhibits the activity of F0F1 ATP synthase. Group: Inhibitors. CAS No. 2101315-36-8. Molecular formula: C22H33ClN2O2. Mole weight: 392.97. Appearance: Solid powder. Purity: >98%. IUPACName: 2-Ethyl-1-(2-(((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-3-methyl-1H-benzo[d]imidazol-3-ium chloride. Canonical SMILES: C[N+]1=C (CC)N (CC (O[C@H]2[C@H] (C (C)C)CC[C@@H] (C)C2)=O)C3=CC=CC=C31. [Cl-]. Catalog: ACM2101315368.
GBR-12935 HCl
GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (¹²³I) are now available for this application. GBR-12935 is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. Group: Inhibitors. Alternative Names: GBR-12935; GBR 12935; GBR12935. CAS No. 67469-81-2. Molecular formula: C28H36Cl2N2O. Mole weight: 487.51. Appearance: Solid powder. Purity: >98%. IUPACName: 1-(2 (Diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine dihydrochloride. Canonical SMILES: [H]Cl. [H]Cl. N1 (CCOC (C2=CC=CC=C2)C3=CC=CC=C3)CCN (CCCC4=CC=CC=C4)CC1. Catalog: ACM67469812.
GDC-0077
Inavolisib, also known as GDC-0077, is a potent and selective PI3K inhibitor. GDC-0077 blocks an enzyme involved in cancer growth called PI3K. GDC0077 binds to and inhibits various members of the PI3K family, including activating mutations in the catalytic alpha isoform PIK3CA. PI3K inhibition prevents the activation of the PI3K-mediated signaling pathway and results in the inhibition of growth and survival of PI3K-overexpressing tumor cells. Group: Inhibitors. Alternative Names: GDC-0077; GDC 0077; GDC0077; Inavolisib; RG6114; RG 6114; RG-6114. CAS No. 2060571-02-8. Molecular formula: C18H19F2N5O4. Mole weight: 407.38. Appearance: Solid powder. Purity: >98%. IUPACName: (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)propanamide. Canonical SMILES: C[C@@H] (C (N)=O)NC1=CC=C (C2=NC (N3[C@H] (C (F)F)COC3=O)=CN2CCO4)C4=C1. Catalog: ACM2060571028.
GDC-0575 freebase
GDC-0575, also known as ARRY-575 and RG7741, is a potent and selective inhibitor of cell cycle checkpoint kinase 1 (Chk1) with an IC50 of 1.2?nM. Chk1 inhibitor GDC-0575 specifically binds to and inhibits Chk1; this may result in tumor cells bypassing Chk1-dependent cell cycle arrest in the S and G2/M phases, which permits the cells to undergo DNA repair prior to entry into mitosis. Group: Inhibitors. Alternative Names: GDC-0575; GDC 0575; GDC0575; ARRY-575; ARRY-575; ARRY575; RG7741; RG-7741; RG 7741; AK 687476; AK-687476; AK687476; GDC-0575 HCl; GDC-0575 hydrochloride. CAS No. 1196541-47-5. Molecular formula: C16H20BrN5O. Mole weight: 378.27. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-N-(4-(3-aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide. Canonical SMILES: O=C (C1CC1)NC2=CNC3=NC=C (Br)C (N4C[C@H] (N)CCC4)=C32. Catalog: ACM1196541475.
GDC6036
GDC-6036, also known as RG6330, is an orally bioavailable, highly potent and selective KRAS G12C inhibitor, with a median IC50 in the sub-nanomolar range and greater than 18,000-fold selectivity for G12C versus non-G12C cell lines. GDC-6036 demonstrates greater potency and selectivity compared with other KRAS G12C inhibitors in vitro, and complete tumor growth inhibition in multiple KRAS G12C-positive cell lines and in xenograft mouse models. We will highlight the research program that led to the discovery and optimization of GDC-6036, which is currently in clinical development. Group: Inhibitors. Alternative Names: GDC-6036; GDC 6036; GDC6036; RG6330; RG-6330; RG 6330. CAS No. 2417987-45-0. Molecular formula: C29H32ClF4N7O2. Mole weight: 622.07. Appearance: To be determined. Purity: >98%. IUPACName: 1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one. Canonical SMILES: NC1=N[C@] ([C@]2=C (C=C3C (N=C (N=C3N4[C@H] (CN (CC4)C (C=C)=O)C)OC[C@H]5N (CCC5)C)=C2F)Cl)=C (C (C)=C1)C (F) (F)F. Catalog: ACM2417987450.
Gedunin
Gedunin is a limonoid with anti-cancer, anti-viral, anti-inflammatory and insecticidal activities. Gedunin acts as a potent Hsp90 inhibitor and induces the degradation of Hsp90-dependent client proteins. Geduni may obstructs the entry of SARS-CoV-2 virus into human host cells and can be used for COVID-19 research. Group: Inhibitors. CAS No. 2753-30-2. Molecular formula: C28H34O7. Mole weight: 482.57. Purity: 0.98. Catalog: ACM2753302.
Genfatinib-d3
2H Labeled Compounds. Alternative Names: Imatinib-d3;Imatinib-d3 (N-methyl-d3). CAS No. 1134803-18-1. Molecular formula: C29H28D3N7O. Mole weight: 496.62. Catalog: ACM1134803181.