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Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine and aziridine, reaction products with epichlorohydrin and polyethylene glycol, formates (salts)
Heterocyclic Organic Compound. Alternative Names: Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine and aziridine, reaction products with epichlorohydrin and polyethylene glycol, formates (salts);POLYAMIDE-ETHYLENEIMINE-EPICHLOROHYDRINRESIN. CAS No. 115340-77-7. Catalog: ACM115340777.
Hexanediol CG
Blend of 1,2-hexanediol and 1,2-octanediol (caprylyl glycol). Stable at high and low pH values, and at high temperatures >100°C. Uses: Hair and skin cosmetics, bath products. Group: Humectants. CAS No. 6920-22-5/1117-86-8. Appearance: Clear, colorless liquid, with mild characteristic odor. Catalog: CI-SC-0031.
Hexanoic acid
Caproic acid is derived from the crude fermentation of butyric acid; or by fractional distillation of natural fatty acids. Used in various flavorings; manufacture of rubber chemicals; varnish dryers; resins; pharmaceuticals. Group: Fatty acids and ester homologs. Alternative Names: Caproic acid. CAS No. 142-62-1. Molecular formula: C6H12O2. Mole weight: 116.16g/mol. Appearance: Colorless liquid. Purity: 99%+. IUPACName: hexanoic acid. Canonical SMILES: CCCCCC(=O)O. Density: 0.92. ECNumber: 205-550-7;274-509-3. Catalog: ACM142621.
Hexaphenylcyclotrisilazane is one of the most important cyclosiloxanes. It has good hydrolysis stability because its phenyl groups have high steric hindrance. Uses: It can effectively improve heat resistance of silicone rubber if it is applied into heat resistance agent to prevent oxidative crosslinking and main chain degradation of silicone rubber side chains. and when it is heated at temperature of 400°C for a long time, it can be formed into polymer for a good heat resistance coating. Group: Silazane compound. Alternative Names: 1,2,2,3,4,4-hexaphenyl-1,3,5,2,4,6-triazatrisilinane. CAS No. 4570-25-6. Mole weight: 591.924. Appearance: White crystal. Density: 1.19(25°C)g/cm³. Catalog: ACM4570256.
hexaprenylhydroquinone sulfate
hexaprenylhydroquinone sulfate. CAS No. 113267-17-7. Catalog: ACM113267177.
Hexyl gallates (Hexyl 3,4,5-trihydroxybenzoate) shows antibacterial activity and inhibits the production of rhamnolipid and pyocyanin by inhibiting RhlR. Hexyl gallate, a alkyl ester derivative of gallic acid, exhibits potent antimalarial activity against Plasmodium falciparum, with IC50 of 0.11 mM. Group: Inhibitors. Alternative Names: N-HEXYL 3,4,5-TRIHYDROXYBENZOATE;HEXYL GALLATE;3,4,5-Trihydroxybenzoic acid hexyl ester;Gallic acid hexyl ester. CAS No. 1087-26-9. Molecular formula: C13H18O5. Mole weight: 254.28. Purity: 0.9989. Catalog: ACM1087269.
Hexyl salicylate may be used as an internal standard for the determination of allergenic ester, benzyl salicylate in propolis specimens using gas chromatography-mass spectrometry (GC/MS), high-performance liquid chromatography (HPLC), and ultraviolet-visible (UV/Vis) spectrophotometry. It may also be used as a standard fragrance material for the quantification of the analyte in wastewater treatment plants using gas chromatography-mass spectrometry (GC?MS). Group: Heterocyclic organic compound. Alternative Names: Benzoic acid, 2-hydroxy-, hexyl ester. CAS No. 6259-76-3. Molecular formula: C13H18O3. Mole weight: 222.28. Purity: 95%+. IUPACName: Hexyl 2-hydroxybenzoate. Canonical SMILES: CCCCCCOC(=O)C1=CC=CC=C1O. Density: 1.04 g/mL at 25 °C(lit.). Catalog: ACM6259763.
Hexyltrimethoxysilane
Liquid. Alternative Names: n-Hexyltrimethoxysilane. CAS No. 3069-19-0. Molecular formula: C9H22O3Si. Mole weight: 206.35. Appearance: Colorless to almost colorless clear liquid. Purity: 0.95. IUPACName: hexyl(trimethoxy)silane. Canonical SMILES: CCCCCC[Si](OC)(OC)OC. ECNumber: 221-331-9. Catalog: ACM3069190.
Hibifolin is a flavonol glycoside that prevents beta-amyloid-induced neurotoxicity in vitro. Hibifolin prevents beta-amyloid-induced neurotoxicity in cultured cortical neurons. Hibifolin is a potential inhibitor of adenosine deaminase. Group: Inhibitors. Alternative Names: Hibifolin; Gossypetin 8-O-beta-D-glucuronide. CAS No. 55366-56-8. Molecular formula: C21H18O14. Mole weight: 494.36. Appearance: Solid powder. Purity: 0.99. IUPACName: beta-D-Glucopyranosiduronic acid, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4-oxo-4H-1-benzopyran-8-yl. Canonical SMILES: O[C@H] ([C@H] ([C@@H] ([C@@H] (C (O)=O)O1)O)O)[C@@H]1OC2=C3C (C (C (O)=C (C4=CC=C (O)C (O)=C4)O3)=O)=C (O)C=C2O. Catalog: ACM55366568.
Hibiscus Extract
Extract obtained from Hibiscus Rosa-Senensis (Hibsicus) flowers. Contains 20% extract dissolved in water and glycerin. Has great antioxidant, toning and purifying properties. Uses: Creams and lotions, gels, toners and hair care products. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 651325-70-1 / 122-99-6. Appearance: Medium to dark amber liquid, characteristic odor. Catalog: CI-SC-0777.
(+/-)-Higenamine HCl - natural
(+/-)-Higenamine HCl is a natural product that has been shown to induce apoptotic cell death in fetal bovine cells. This compound has been demonstrated to have a specific treatment effect on human vasodilation and blood flow. It also has been shown to have an inhibitory effect on reactive oxygen species (ROS) and can be used as an experimental model for the study of ROS-mediated apoptotic cell death. (+/-)-Higenamine HCl can be found in traditional Chinese herbs, such as huangqi, and has been shown to inhibit the production of reactive oxygen species in vitro. Group: Other alkaloids. CAS No. 11041-94-4. Molecular formula: C16H17NO3·HCl. Mole weight: 307.77 g/mol. Canonical SMILES: C1CNC (C2=CC (=C (C=C21)O)O)CC3=CC=C (C=C3)O. Cl. Catalog: ACM11041944.
Hinokitiol
Hinokitiol is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities. Group: Inhibitors. Alternative Names: Rikecolor Kuchinashi 20. CAS No. 499-44-5. Molecular formula: C10H12O2. Mole weight: 164.2. Appearance: White solid. Purity: 0.98. IUPACName: 2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one. Canonical SMILES: CC(C)C1=CC(=O)C(=CC=C1)O. Catalog: ACM499445.
Hirudin
Hirudin is a thrombin inhibitor with blood anticoagulant property. Hirudin has potent anti-thrombotic, wound repair, anti-fibrosis, anti-tumor and anti-hyperuricemia effects. Hirudin also affects diabetic complications, cerebral hemorrhage, and others. Group: Inhibitors. CAS No. 8001-27-2. Molecular formula: C287H440N80O110S6. Mole weight: 7027. Appearance: Solid. Catalog: ACM8001272.
Hirudin(54-65)(desulfated)
Heterocyclic Organic Compound. Alternative Names: HIRUDIN (54-65) (DESULFATED);HIRUDIN FRAGMENT 54-65 NON-SULFATED;H-GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN-OH;GLY-ASP-PHE-GLU-GLU-ILE-PRO-GLU-GLU-TYR-LEU-GLN;Hirudin. CAS No. 113274-56-9. Molecular formula: C66H93N13O25. Mole weight: 1468.52. Catalog: ACM113274569.
Histamine Dihydrochloride
Histamine dihydrochloride (INN, trade name Ceplene) is a salt of histamine which is used as a drug for the prevention of relapse in patients diagnosed with acute myeloid leukemia (AML).It is an FDA approved active ingredient for topical analgesic use and is available in such products as Australian Dream Cream, which is used for the temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, sprains, and strains. Uses: Present in most mammalian tissues; primarily stored in mast cells and basophils. exhibits multiple biological effects through at least 3 specific receptors. induces bronchoconstriction and vasodilation; stimulates gastric acid secretion; and acts as a neurotransmitter. histamine has been identified as a bedbug pheromone. Group: Other alkaloids. Alternative Names: 2-(3H-Imidazol-4-yl)ethanamine dihydrochloride. CAS No. 56-92-8. Molecular formula: C5H11Cl2N3. Mole weight: 184.07. Appearance: White to off-white solid. Purity: 0.98. IUPACName: 2-(1H-imidazol-5-yl)ethanamine;dihydrochloride. Canonical SMILES: C1=C(NC=N1)CCN.Cl.Cl. Density: 1.14 g/cm³. Catalog: ACM56928.
Hiv-1 env protein gp120(278-292)(strains bh10,bh8,hxb2,hxb3,pv22)
Heterocyclic Organic Compound. Alternative Names: GP120 (313-327);H-ARG-ILE-GLN-ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE-GLY-LYS-OH;HIV (GP120) FRAGMENT (315-329);ARG-ILE-GLN-ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE-GLY-LYS;R15K;HIV-1 env Protein gp120 (278-292) (strains BH10, BH8, HXB2, HXB3, PV22). CAS No. 114991-28-5. Molecular formula: C73H126N26O18. Mole weight: 1655.94. Catalog: ACM114991285.
Hiv(gp120)fragment(308-331)
Heterocyclic Organic Compound. Alternative Names: ASN-ASN-THR-ARG-LYS-SER-ILE-ARG-ILE-GLN-ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE-GLY-LYS-ILE-GLY;HIV ENVELOPE PROTEIN (GP120) FRAGMENT 308-331;HIV (GP120) FRAGMENT (308-331);H-ASN-ASN-THR-ARG-LYS-SER-ILE-ARG-ILE-GLN-ARG-GLY-PRO-GLY-ARG-ALA-PHE-VAL-THR-ILE. CAS No. 115416-08-5. Molecular formula: C114H199N41O31. Mole weight: 2640.06. Catalog: ACM115416085.
HJC0152
HJC0152 is a signal transducer and activator of transcription 3 (STAT3) inhibitor against human head and neck squamous cell carcinoma (HNSCC). Group: Inhibitors. Alternative Names: HJC0152; HJC 0152; HJC-0152. CAS No. 1420290-99-8. Molecular formula: C15H14Cl3N3O4. Mole weight: 406.64. Appearance: Solid powder. Purity: >98%. IUPACName: 2-(2-Amino-ethoxy)-5-chloro-N-(2-chloro-4-nitrophenyl)benzamide Hydrochloride. Canonical SMILES: O=C (NC1=CC=C ([N+] ([O-])=O)C=C1Cl)C2=CC (Cl)=CC=C2OCCN. [H]Cl. Catalog: ACM1420290998.
HKI-357
HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation. Group: Inhibitors. Alternative Names: HKI-357; HKI357; HKI 357. CAS No. 848133-17-5. Molecular formula: C31H29ClFN5O3. Mole weight: 574.05. Appearance: Solid powder. Purity: >98%. IUPACName: (E)-N-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide. Canonical SMILES: O=C (NC1=C (OCC)C=C2N=CC (C#N)=C (NC3=CC=C (OCC4=CC=CC (F)=C4)C (Cl)=C3)C2=C1)/C=C/CN (C)C. Catalog: ACM848133175.
Heterocyclic Organic Compound. Alternative Names: H-LYS-PHE-GLY-LYS-OH ACETATE SALT;H-LYS-PHE-GLY-LYS-OH ACOH;H-Lys-Phe-Gly-Lys-OH. CAS No. 114577-12-7. Molecular formula: C23H38N6O5. Mole weight: 538.64. Catalog: ACM114577127.
HM43239
HM43239 is an orally active small molecule inhibitor of FLT3 that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. HM43239 directly inhibits the kinase activity of FLT3 as a reversible Type I inhibitor and effectively modulates downstream p-STAT5 and p-ERK. HM43239 also demonstrated inhibition of SYK, JAK1/2 and TAK1, known to be involved in tumor cell proliferation and/or differentiation HM43239 monotherapy induced dose-dependent regression of tumor growth in FLT3 wild-type and FLT3 mutated leukemia cancer cell line. Group: Inhibitors. Alternative Names: HM43239; HM-43239; HM 43239. CAS No. 2569527-64-4. Molecular formula: C29H33ClN6. Mole weight: 501.08. Appearance: Solid powder. Purity: >98%. IUPACName: rel-5-Chloro-N-[3-cyclopropyl-5-[[(3R,5S)-3,5-dimethyl-1-piperazinyl]methyl]phenyl]-4-(6-methyl-1H-indol-3-yl)-2-pyrimidinamine. Canonical SMILES: CC1=CC2=C (C=C1)C (C3=NC (NC4=CC (CN5C[C@@H] (C)N[C@@H] (C)C5)=CC (C6CC6)=C4)=NC=C3Cl)=CN2. Catalog: ACM2569527644.
HMN-176
HMN-176 is an active metabolite of the synthetic antitumor compound HMN-214. HMN-176 shows potent cytotoxicity toward various human tumor cell lines, and in mitotic cells, it causes cell cycle arrest at M phase through the destruction of spindle polar bodies, followed by the induction of DNA fragmentation. However, no direct interactions of HMN-176 with tubulin are observed. Moreover, in animal models, it was observed that oral administration of the prodrug HMN-214 caused no significant nerve toxicity, a severe side effect often associated with microtubule binding agents such as Taxol and VCR.3 In Phase I clinical trials, HMN-214 has caused sensory neuropathy and ileus in some patients. However, the grade and frequency of these adverse effects were much lower than those of typical microtubule binding agents. As expected from the mechanism of action of HMN-214 (induction of G2-M arrest in dividing cells), the main adverse effect was neutropenia. (Source: CANCER RESEARCH 63, 6942 -6947). Group: Inhibitors. Alternative Names: HMN176; HMN 176; HMN-176. CAS No. 173529-10-7. Molecular formula: C20H18N2O4S. Mole weight: 382.43. Appearance: Solid powder. Purity: >98%. IUPACName: (E) -4- (2- (4-methoxyphenylsulfonamido) styryl) pyridine 1-oxide. Canonical SMILES: O=S (NC1=CC=CC=C1/C=C/C2=CC=[N+] ([O-])C=C2) (C3=CC=C (OC)C=C3)=O. Catalog: ACM173529107.
Hokkaido Orange
A manufactured pigment Excellent UV Stability Suitable for all mediums Not Cosmetic or Pharmaceutical Grade Lime and Cement Color Stable. Group: Pigments. CAS No. 85536-73-8. Catalog: ACM85536738.
Holmium Hydroxide
Holmium has the hHighest magnetic strength of any element, and therefore is used to create the strongest artificially generated magnetic fields. Since it can absorb nuclear fission-bred neutrons, it is also used as a burnable poison to regulate nuclear reactors. It is one of the colorants used for cubic zirconia and glass, providing yellow or red coloring. Uses: Holmium hydrate, has specialized uses in ceramics, glass, phosphors and metal halide lamp, and catalyst. Group: Heterocyclic organic compound. CAS No. 12054-57-8. Molecular formula: Ho(OH)3.xH2O. Mole weight: 215.95(anhy)g/mol. Appearance: Light yellow crystalline. Catalog: ACM12054578.
Holmium(III) Acetylacetonate Hydrate
Holmium Acetylacetonate hw is a Holmium source that is soluble in organic solvents as an organometallic compound (also known as metalorganic, organo-inorganic and metallo-organic Acetylacetonate Packaging, Lab Quantitycompounds). Group: Heterocyclic organic compound. Alternative Names: HOLMIUM(III) ACETYLACETONATE HYDRATE;2,4-Pentanedione holmium(III) derivative, Ho(acac)3. CAS No. 22498-66-4. Molecular formula: Ho(C4H7O2)3 xH2O. Mole weight: 462.25(anhydrousbasis)g/mol. Appearance: White Powder. Catalog: ACM22498664.
Holmium Nanoparticle Dispersion
Holmium Nanoparticle Dispersions are suspensions of holmium nanoparticles in water or various organic solvents such as ethanol or mineral oil. Group: Nanoparticle dispersions. Alternative Names: Holmium nanopowder suspension, aqueous Holmium nanoparticle solution, Holmium nanofluid. CAS No. 7440-60-0. Molecular formula: Ho. Mole weight: 165g/mol. Appearance: solid. Purity: 99.9%, 99.99%, 99.999%. Density: 8.795g/mL. ECNumber: 231-169-0. Catalog: ACM7440600.
Homatropine Hydrobromide
Natural alkaloid. Group: Tropane alkaloids. Alternative Names: Mandelyltropeine hydrobromide;Tropine mandelate hydrobromide; (1R, 5S)-3-{[(2R)-2-hydroxy-2-phenylacetyl]oxy}-8-methyl-8-azoniabicyclo[3.2.1]octane; (±)-Homatropine bromide;1αH, 5αH-Tropan-3α-ol, mandelate (ester), hydrobromide;8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate;8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate Hydrobromide (1:1);Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide;Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1). CAS No. 51-56-9/87-00-3. Molecular formula: C16H21NO3·HBr. Mole weight: 356.26g/mol. Appearance: White to Almost white powder to crystal. Purity: >99.0%(T). ECNumber: 200-105-3. Catalog: ACM51569-2.
Homobutein
Homobutein a natural chalcones (can be found in many medicinal plants, fruits, vegetables, spices and nuts), is a potent HDACs/NF-κB dual inhibitor with IC50s of 190 and 38 μM, respectively. Homobutein also a chelator of iron (II and III) cations, shows various activities, including anticancer, anti-inflammatory, antiparasite and antioxidation. Group: Inhibitors. Alternative Names: 2',4,4'-TRIHYDROXY-3-METHOXY CHALCONE;3-METHOXY-2',4',4-TRIHYDROXYCHALCONE;HOMOBUTEIN;(E)-2',4,4'-trihydroxy-3-methoxychalcone;3-O-methylbutein;HOMOBUTEIN WITH HPLC;HOMOBUTEIN hplc;(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one. CAS No. 34000-39-0. Molecular formula: C16H14O5. Mole weight: 286.3. Appearance: Powder. Purity: 0.98. IUPACName: (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one. Canonical SMILES: COC1=C (C=CC (=C1)C=CC (=O)C2=C (C=C (C=C2)O)O)O. Density: 1.369 g/cm³. ECNumber: 251-782-7. Catalog: ACM34000390.
Homogentisic Acid
Homogentisic acid (2,5-dihydroxyphenylacetic acid) is a phenolic acid found in Arbutus unedo (strawberry-tree) honey. It is also present in the bacterial plant pathogen Xanthomonas campestris pv. phaseoli as well as in the yeast Yarrowia lipolytica where it is associated with the production of brown pigments.It is less commonly known as melanic acid, the name chosen by William Prout. Group: Heterocyclic organic compound. Alternative Names: Alcapton. CAS No. 451-13-8. Molecular formula: C8H8O4. Mole weight: 168.15. Appearance: Crystalline. Purity: 0.97. IUPACName: 2-(2,5-Dihydroxyphenyl)acetic acid. Canonical SMILES: C1=CC(=C(C=C1O)CC(=O)O)O. Density: 1.3037 g/cm³. Catalog: ACM451138.
Homopiperazine
Homopiperazine acts as a corrosion inhibitor for iron. It has also been used in the preparation of potent H3 receptor antagonists for use as treatments for neurodegenerative conditions such as Alzheimers disease. Group: Heterocyclic organic compound. Alternative Names: hexahydro-1H-1,4-diazepine;homopiperazine;tetrahydro-1,4-diazepine;hexahydro-4H-1,4-diazepine;1H-1,4-Diazepine, hexahydro-. CAS No. 505-66-8. Molecular formula: C5H12N2. Mole weight: 100.16. Appearance: The white solid (30ºC) or colorless viscosity liquids (30ºCand above). Density: 0.861 g/cm³. Catalog: ACM505668.
Homoplantaginin
Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinflammatory and antioxidant properties. Homoplantaginin could inhibit TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation. Group: Inhibitors. Alternative Names: HOMOPLANTAGININ;7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-Benzopyran-4-one;Hispidulin 7-glucoside;Hispiduloside;4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-. CAS No. 17680-84-1. Molecular formula: C22H22O11. Mole weight: 462.4. Appearance: white crystalline. Purity: 0.96. IUPACName: 5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one. Canonical SMILES: COC1=C (C=C2C (=C1O)C (=O)C=C (O2)C3=CC=C (C=C3)O)OC4C (C (C (C (O4)CO)O)O)O. Density: 1.609. Catalog: ACM17680841.
Homosalate
Liquid oil soluble UVB sunscreen. Homosalate (other name is homomenthylsalicylate) is an organic compound, an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Uses: Sunscreen emulsions, gels, creams, sticks, makeup. Group: Heterocyclic organic compound. Alternative Names: 3,3,5-Trimethylcyclohexyl salicylate;Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester. CAS No. 118-56-9. Molecular formula: C16H22O3. Mole weight: 262.34. Appearance: Colorless to pail yellow liquid, faint odor. Purity: 0.98. Density: 1.1 g/cm³. Catalog: ACM118569.
Homozimelidine
Heterocyclic Organic Compound. CAS No. 112969-65-0. Catalog: ACM112969650.
Honeydew Extract
Extract obtained from Cucumis Melo (Melon) fruits. Contains 20% extract dissolved in water and glycerin. Has great moisturizing and stimulating properties. Uses: Lotions, gels, tonics, hair care products. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 90063-94-8 / 122-99-6. Appearance: Colorless to light yellow liquid, characteristic odor. Catalog: CI-SC-0910.
Honey Extract
Obtained from organic apiculture, honey is a natural humectant and moisturizer able to retain moisture on the skin. Uses: Creams and lotions, hair care products, baby care products. Group: Humectants. CAS No. 7732-18-5 / 504-63-2 / 91052-92-5 / 8026-66-8 / 590-00-1 / 532-32-1. Appearance: Clear, yellowish liquid. Catalog: CI-HC-0135.
Honeysuckle Blend
Plant based liquid concentrate that has antimicrobial properties. Active components are isolated from herbs, namely Lonicera Japonica (Japanese Honeysuckle) and Lonicera Caprifolium. The concentrate is suitable for the antimicrobial protection of cosmetic and pharmaceutical applications. Uses: All kinds of emulsions, surfactant systems (cleansers), and other products that contain water. Group: Skin actives. CAS No. 84603-62-3/223749-79-9/773218-5. Appearance: Light clear yellow liquid, moderate characteristic odor. Catalog: CI-SC-0993.
Honeysuckle Extract
Extract obtained from Lonicera Caprifolum (Honeysuckle) flowers. Contains 20% extract dissolved in water and glycerin. Has antimicrobial, aromatic and cleansing properties. Uses: Creams and lotions, soaps, and cleansers. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 84603-62-3 / 122-99-6. Appearance: Light to medium amber liquid, characteristic odor. Catalog: CI-SC-0831.
Honokiol
Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the activation of Akt. Honokiol can readily cross the blood brain barrier. Group: Inhibitors. Alternative Names: 3',5-Diallyl-2,4'-biphenyldiol. CAS No. 35354-74-6. Molecular formula: C18H18O2. Mole weight: 266.33. Appearance: White powder. Purity: 0.98. IUPACName: 2-(4-Hydroxy-3-prop-2-enylphenyl)-4-prop-2-enylphenol. Canonical SMILES: C=CCC1=CC (=C (C=C1)O)C2=CC (=C (C=C2)O)CC=C. Density: 1.107±0.06 g/ml. Catalog: ACM35354746.
Extract obtained from dried Humulus Lupulus (Hops) strobiles. Contains 20% extract dissolved in water and glycerin. Has anti-irritating, soothing and calming properties. Uses: Creams and lotions, bath preparations. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 8016-25-9 / 8060-28-4 / 122-99-6. Appearance: Light to medium golden amber liquid, characteristic odor. Catalog: CI-SC-0793.
Horse Chestnut Extract
Natural Horse Chestnut extract made from whole plant. Other parts, for example, the bark have been used as a yellow dye. Contains 20% of extract dissolved in water and glycerin. Uses: Creams & lotions, shampoos & conditioners, hair mask, body wraps, face cleansers, toners and moisturizers, masks and gels. Group: Skin actives. CAS No. 56-81-5/7732-18-5/8053-39-2/122-99-6. Appearance: Light yellow liquid, characteristic odor. Catalog: CI-SC-0665.
Horseradish Extract
Extract obtained from Cochlearia Armoracia (Horseradish) roots. Contains 20% extract dissolved in water and glycerin. Has purifying, anti-blemish and stimulating properties. Uses: Creams and lotions for skin lightening, cleaners and shampoos. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 84775-62-2 / 122-99-6. Appearance: Light to pale yellow liquid, characteristic odor. Catalog: CI-SC-0859.
Horsetail Extract
Extract obtained from Equisetum Arvense L. (Horsetail) plants. Contains 20% extract dissolved in water and glycerin. Natural emulsifying and mattifying properties; creates a matte finish while maintaining good moisturizing features. Used for centuries as anti-irritant and soothing agent. Also used in deodorants. Uses: All kinds of skin and hair care products. also useful in makeup products. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 71011-23-9 / 122-99-6. Appearance: Colorless to light brown liquid, characteristic odor. Catalog: CI-SC-0785.
Heterocyclic Organic Compound. Alternative Names: L-PROLYL-BETA-ALANINE;H-PRO-BETA-ALA-OH;L-PROLYL-B-ALANINE. CAS No. 112558-45-9. Molecular formula: C8H14N2O3. Mole weight: 186.21. Catalog: ACM112558459.
HQ461
HQ461 is a Molecular-glue degrader. HQ461 acts by promoting an interaction between CDK12 and DDB1-CUL4-RBX1 E3 ubiquitin ligase, leading to polyubiquitination and degradation of CDK12-interacting protein Cyclin K (CCNK). Degradation of CCNK mediated by HQ461 compromised CDK12 function, leading to reduced phosphorylation of a CDK12 substrate, downregulation of DNA damage response genes, and cell death. Structure-activity relationship analysis of HQ461 revealed the importance of a 5-methylthiazol-2-amine pharmacophore and resulted in an HQ461 derivate with improved potency. Group: Inhibitors. Alternative Names: HQ461; HQ-461; HQ 461. CAS No. 1226443-41-9. Molecular formula: C15H15N5OS2. Mole weight: 345.44. Appearance: Solid powder. Purity: >98%. IUPACName: 2-(2-((6-methylpyridin-2-yl)amino)thiazol-4-yl)-N-(5-methylthiazol-2-yl)acetamide. Canonical SMILES: CC1C=CC=C (NC2=NC (CC (=O)NC3=NC=C (C)S3)=CS2)N=1. Catalog: ACM1226443419.
HS-173
HS-173 is a potent PI3Kα inhibitor with potential anticancer activity. HS-173 inhibited the PI3K signaling pathway, and showed anti-proliferative effects on cancer cells. Also, HS-173 induced cell cycle arrest at the G(2)/M phase and apoptosis. In addition, HS-173 decreased the expression HIF-1α and VEGF which play an important role in angiogenesis. This effect was confirmed by the suppression of tube formation and migration assay in vitro. Furthermore, HS-173 diminished blood vessel formation in the Matrigel plug assay in mice. Therefore, HS-173 is considered as a novel drug candidate to treat cancer patients. Group: Inhibitors. Alternative Names: HS173; HS 173; HS-173. CAS No. 1276110-06-5. Molecular formula: C21H18N4O4S. Mole weight: 422.46. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate. Canonical SMILES: O=C (C1=CN=C2C=CC (C3=CC (NS (=O) (C4=CC=CC=C4)=O)=CN=C3)=CN21)OCC. Catalog: ACM1276110065.
HSD-016
HSD-016 is a potent, selective, and efficacious 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor. Group: Inhibitors. Alternative Names: HSD-016; HSD 016; HSD016; HSD-16; HSD 16; HSD16. CAS No. 946396-92-5. Molecular formula: C21H21F7N2O3S. Mole weight: 514.46. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-1,1,1-trifluoro-2-(3-(((R)-4-(4-fluoro-2-(trifluoromethyl)phenyl)-2-methylpiperazin-1-yl)sulfonyl)phenyl)propan-2-ol. Canonical SMILES: O[C@] (C (F) (F)F) (C)C1=CC=CC (S (=O) (N2[C@H] (C)CN (C3=CC=C (F)C=C3C (F) (F)F)CC2)=O)=C1. Catalog: ACM946396925.
H-Ser(tbu)-ome.hcl
Heterocyclic Organic Compound. CAS No. 114-97-5. Purity: 0.96. Catalog: ACM114975.
HT-61
HT-61, also known as HY-50A, is a pyrroloquinolone antibiotic potentially for the treatment of staphylococcal infections. HT61 was effective at reducing biofilm viability and was associated with increased expression of cell wall stress and division proteins, confirming its potential as a treatment for S. aureus biofilm infections. HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. Group: Others. Alternative Names: HT-61; HT61; HT 61; HY-50A; HY 50A; HY50A. CAS No. 936622-80-9. Molecular formula: C26H24N2O. Mole weight: 380.49. Appearance: Solid powder. Purity: >98%. IUPACName: 4-methyl-1-phenethyl-8-phenoxy-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline. Canonical SMILES: CC1=NC2=CC=C (OC3=CC=CC=C3) C=C2C4=C1CCN4CCC5=CC=CC=C5. Catalog: ACM936622809.
HTH-01-015
HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases, including additional AMPK family members. The administration of HTH-01-015 to MEFs (mouse embryonic fibroblasts) significantly inhibits migration in a wound-healing assay to a similar extent as NUAK1-knockout. HTH-01-015 also inhibit proliferation of MEFs to the same extent as NUAK1 knockout and U2OS cells to the same extent as NUAK1 shRNA knockdown. HTH-01-015 impaired the invasive potential of U2OS cells in a 3D cell invasion assay to the same extent as NUAK1 knockdown. HTH-01-015 will serve as useful chemical probes to delineate the biological roles of the NUAK kinases. Group: Inhibitors. Alternative Names: HTH-01-015; HTH01-015; HTH 01-015; HTH-01015; HTH01015; HTH 01015. CAS No. 1613724-42-7. Molecular formula: C26H28N8O. Mole weight: 468.57. Appearance: Solid powder. Purity: >98%. IUPACName: 4,5,13-trimethyl-2-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)-5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one. Canonical SMILES: CC1=C (N (C)C (C2=CC (C=CC=C3)=C3C=C2N4C)=O)C4=NC (NC5=CN (N=C5)C6CCNCC6)=N1. Catalog: ACM1613724427.
Humantenidine
Indole Alkaloids. Alternative Names: 14-Hydroxygelsenicine. CAS No. 114027-39-3. Mole weight: 342.39. Purity: 95%+. Catalog: ACM114027393.
Humic acid sodium salt
Sodium humate is made from natural lignite or leonardite, appears in black powder, granule and flake, it has been widely used in animal feed additive, aquiculture, industry as well as agriculture. Uses: Humic acid sodium salt is suitable reagent used to study the hygroscopic growth of solid aerosol particles consisting of mixtures of ammonium sulfate, adipic acid and humic acid mixtures. it is suitable reagent used to study the phase transitions and hygroscopic growth of humic acid aerosols by fourier transform infra-red (ftir) spectroscopy and tandem differential mobility analysis (tdma). Group: Heterocyclic organic compound. CAS No. 68131-04-4. Molecular formula: C9H8Na2O4. Mole weight: 226.13696. ECNumber: 268-608-0. Catalog: ACM68131044.
HUN51998
HUN51998, also known as CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor. HUN51998 was first reported in patent WO 2018144900, which functioned as a antagonist of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2)? with potential application for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related itch, anosmia, migraine event, and?/or pain (e.g., neuropathic pain). Group: Inhibitors. Alternative Names: CRMP2-Ubc9-NaV1.7 inhibitor; HUN51998; HUN-51998; HUN 51998. CAS No. 2241651-99-8. Molecular formula: C34H31F2N3O3. Mole weight: 567.64. Appearance: Solid powder. Purity: >98%. IUPACName: (4-(1-(3-Fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(3-fluorobenzyloxy)-3-methoxyphenyl)methanone. Canonical SMILES: O=C (N1CCC (C2=NC3=CC=CC=C3N2CC4=CC=CC (F)=C4)CC1)C5=CC=C (OCC6=CC=CC (F)=C6)C (OC)=C5. Catalog: ACM2241651998.
HUN78821
HUN78821, also known as 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one dihydrochloride is a chemical reagent for research use. Group: Others. Alternative Names: HUN78821; HUN 78821; HUN-78821. CAS No. 1638178-82-1. Molecular formula: C24H28Cl2N4O. Mole weight: 459.42. Appearance: Solid powder. Purity: >98%. IUPACName: 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one dihydrochloride. Canonical SMILES: O=C1N (CC2=CC=CC=C2C)C3=NCCN3C4=C1CN (CC5=CC=CC=C5)CC4. [H]Cl. [H]Cl. Catalog: ACM1638178821.
Hyaluronic acid
For whitening and moisturizing. Group: Material of cosmetics. Alternative Names: Hyaluronic Acid Sodium Salt. CAS No. 9004-61-9. Molecular formula: C28H44N2O23. Mole weight: 403.31. Appearance: White powder. Density: 1.78 g/cm³. Catalog: ACM9004619.
Hyaluronic Acid Multiplex
Concentrated blend of multiple hyaluronic acid. Contains medium, low, oligo, high and very high molecular weights to form stereoscopic sponge-like structures for comprehensive multi-level skin care. Average molecular weight 215kDa. Uses: Anti-aging & anti-wrinkle lotions, serums and creams. moisturizing products, sun care products, toners, facial mists. Group: Humectants. CAS No. 9067-32-7 / 7732-18-5 / 6920-22-5 / 70445-33-9. Appearance: Colorless, transparent, odorless liquid. Catalog: CI-SC-0044.
Hyaluronic Acid Multiplex 7
Optimized ratio of seven unique molecular weights of hyaluronic acid. 3'000-2'300'000 DaMWFor comprehensive multi-level skin care. Uses: Anti-aging & anti-wrinkle lotions, serums and creams. moisturizing products, sun care products, toners, facial mists. Group: Humectants. CAS No. 9067-32-7/7732-18-5/6920-22-5. Appearance: Clear, colorless liquid. Catalog: CI-SC-0043.
Hydrated Silica
Hydrated Silica is a form of silicon dioxide that is used in a number of personal care and cosmetic products. It provides mild abrasion properties that can exfoliate the face properly and aid in the removal of dead skin cells. Hydrated Silica can commonly be found in toothpaste, exfoliating body washes, and facial scrubs. It is also a thickening and viscosity-controlling agent that improves the feel and texture of the products that it is used in. The chemical formula of Hydrated Silica is H10O3Si. Uses: 1. hygiene products - hydrated silica is commonly used as an abrasive agent in toothpaste, as it helps in removing stains from teeth without damaging the enamel. 2. skincare - it is used as an ingredient in exfoliating facial cleansers, as it helps in removing dead skin cells and unclogging pores. 3. food and beverages - it is used as a food additive in powdered products, such as coffee creamers. Group: Skin actives. CAS No. 10279-57-9 / 1343-98-2 / 7631-86-9 / 112926-00-8 / 63231-67-4. Appearance: white, odorless, and tasteless powder. Catalog: CI-SC-0584.