Alfa Chemistry. - Products
Alfa Chemistry is an ISO 9001:2015 Certified Supplier of various building blocks, reagents, catalysts, nanomaterials, reference materials, and research chemicals. In-stock products can be shipped quickly.
| Product | Description | |
|---|---|---|
| Fmoc-D-Nva-OH | Standard building block of introduction of D-norvaline amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Nva-OH, N-α-Fmoc-D-norvaline. CAS No. 144701-24-6. Mole weight: 339.39. Catalog: ACM144701246. |  |
| Fmoc-D-Orn(Boc)-OH | Standard building block of introduction of D-ornithine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Orn(Boc)-OH, N-α-Fmoc-N-δ-t.-Boc-D-ornithine. CAS No. 118476-89-4. Mole weight: 454.52. Catalog: ACM118476894. | |
| Fmoc-D-Phg-OH | Standard building block of introduction of D-phenylglycine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Phg-OH, N-α-Fmoc-D-phenylglycine. CAS No. 111524-95-9. Mole weight: 373.4. Catalog: ACM111524959. | |
| Fmoc-Dpr(Boc)-OH | Standard building block for introduction of diaminopropionic acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Dpr(Boc)-OH, N-α-Fmoc-N-β-t.-Boc-L-diaminopropionic acid. CAS No. 162558-25-0. Molecular formula: C23H26N2O6. Mole weight: 426.46. Catalog: ACM162558250. | |
| Fmoc-D-Pro-OH | Standard building block of introduction of D-proline amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Pro-OH, N-α-Fmoc-D-proline. CAS No. 101555-62-8. Molecular formula: C20H19NO4. Mole weight: 337.37. Catalog: ACM101555628-1. | |
| Fmoc-D-propargylglycine | Fmoc-D-propargylglycine is an amino acid derivative that is commonly used in peptide synthesis. Peptides are short chains of amino acids that are linked together by peptide bonds. They play a critical role in many biological processes, including hormone regulation, enzyme catalysis, and immune response. Fmoc-D-propargylglycine is a non-natural amino acid derivative that is commonly used as a building block in peptide synthesis due to its high reactivity and versatility. Uses: Fmoc-d-propargylglycine has a wide range of potential applications in scientific experiments. it is commonly used as a building block in peptide synthesis and has been investigated for its potential as an inhibitor of protein-protein interactions. it has also been studied for its potential therapeutic applications in various diseases, including cancer and alzheimer's disease. Group: Amino acids. CAS No. 220497-98-3. Molecular formula: C20H17NO4. Mole weight: 335.4. Purity: Peak Area by HPLC ≥95%. IUPACName: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-ynoic acid. Canonical SMILES: C#CCC (C (=O)O)NC (=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Density: 1.3±0.1 g/cm3. Catalog: ACM220497983. | |
| Fmoc-D-Ser-OH | Standard building block of introduction of D-serine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Ser-OH, N-α-Fmoc-D-serine. CAS No. 116861-26-8. Mole weight: 327.33. Catalog: ACM116861268. | |
| Fmoc-D-Ser(tBu)-OH | Standard building block of introduction of D-serine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Ser(tBu)-OH, N-α-Fmoc-O-t.-butyl-D-serine. CAS No. 128107-47-1. Molecular formula: C22H25NO5. Mole weight: 383.44. Catalog: ACM128107471. | |
| Fmoc-D-Thi-OH | Standard building block of introduction of D-thienylalanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Thi-OH, N-α-Fmoc-β-thienyl-D-alanine. CAS No. 201532-42-5. Mole weight: 393.46. Catalog: ACM201532425. | |
| Fmoc-D-Thr(PO(OBzl)OH)-OH | An excellent building block for the preparation of D-phosphothreonine-containing peptides by Fmoc SPPS. This derivative can be introduced using standard activation methods, such as PyBOPand TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Thr(PO(OBzl)OH)-OH, N-α-Fmoc-O-benzyl-D-phosphothreonine. CAS No. 937171-63-6. Molecular formula: C26H26NO8P. Mole weight: 511.46. IUPACName: (2R, 3S) -2- (9H-fluoren-9-ylmethoxycarbonylamino) -3-[hydroxy (phenylmethoxy) phosphoryl]oxybutanoic acid. Canonical SMILES: CC (C (C (=O)O)NC (=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)OP (=O) (O)OCC4=CC=CC=C4. Density: 1.4±0.1 g/cm3. Catalog: ACM937171636. | |
| Fmoc-D-Thr(tBu)-OH | Standard building block of introduction of D-threonine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Thr(tBu)-OH, N-α-Fmoc-O-t.-butyl-D-threonine / (2R,3S). CAS No. 138797-71-4. Molecular formula: C23H27NO5. Mole weight: 397.46. Catalog: ACM138797714. | |
| Fmoc-D-Tic-OH | Standard building block of introduction of D-Tic amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Tic-OH, N-1-Fmoc-D-1,2,3,4,-tetrahydro-isoquinoline-3-carboxylic acid. CAS No. 130309-33-0. Mole weight: 399.44. Catalog: ACM130309330. | |
| Fmoc-D-Trp(Boc)-OH | Standard building block of introduction of D-tryptophan amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Trp(Boc)-OH, N-α-Fmoc-N-in-t.-Boc-D-tryptophan. CAS No. 163619-04-3. Molecular formula: C31H30N2O6. Mole weight: 526.58. Catalog: ACM163619043. | |
| Fmoc-D-Trp-OH | Standard building block of introduction of D-tryptophan amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Trp-OH, N-α-Fmoc-D-tryptophan. CAS No. 86123-11-7. Mole weight: 426.46. Catalog: ACM86123117. | |
| Fmoc-D-Tyr(tBu)-OH | Standard building block of introduction of D-tyrosine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Tyr(tBu)-OH, N-α-Fmoc-O-t.-butyl-D-tyrosine. CAS No. 118488-18-9. Molecular formula: C28H29NO5. Mole weight: 459.53. Catalog: ACM118488189. | |
| Fmoc-D-Val-OH | Standard building block of introduction of D-valine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-D-Val-OH, N-α-Fmoc-D-valine. CAS No. 84624-17-9. Molecular formula: C20H21NO4. Mole weight: 339.39. Purity: Peak Area by HPLC ≥95%. Catalog: ACM84624179. | |
| Fmoc-GABA-OH | Standard building block for introduction of gamma aminobutyric acid amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: 4-(Fmoc-amino)butyric acid, Fmoc-GABA, Fmoc-γ-Abu-OH, N-γ-Fmoc-γ-aminobutyric acid. CAS No. 116821-47-7. Mole weight: 325.36. Canonical SMILES: OC(=O)CCCNC(=O)OCC1c2ccccc2-c3ccccc13. Catalog: ACM116821477-1. | |
| Fmoc-γ-azidohomoalanine | A useful tool for the synthesis of branched, side-chain modified, cyclic peptides and peptide tools for click chemistry by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-γ-azidohomoalanine. CAS No. 942518-20-9. Molecular formula: C19H18N4O4. Mole weight: 366.37. Purity: Peak Area by HPLC ≥95%. Catalog: ACM942518209. | |
| Fmoc-Gln(Dmcp)-OH | A superior derivative to Fmoc-Gln(Trt)-OH for the synthesis of Gln-containing peptides by Fmoc SPPS. Fmoc-Gln(Dmcp)-OH is more soluble in DMF than Fmoc-Gln(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Gln(Dmcp)-OH, N-α-Fmoc-N-γ-(1-cyclopropyl-1-methylethyl)-L-glutamine. CAS No. 172947-20-5. Mole weight: 450.53. Catalog: ACM172947205. | |
| Fmoc-Gln-OH | Building block for introduction of glutamine by Fmoc SPPS. Not compatible with uronium and phosphonium coupling reagents. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Gln-OH, N-α-Fmoc-L-glutamine. CAS No. 71989-20-3. Mole weight: 368.38. Catalog: ACM71989203. | |
| Fmoc-Gln(Trt)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Fmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp. Literature references P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Gln(Trt)-OH, N-α-Fmoc-N-γ-trityl-L-glutamine. CAS No. 132327-80-1. Molecular formula: C39H34N2O5. Mole weight: 610.7. Catalog: ACM132327801. | |
| Fmoc-Glu-OAll | Orthogonally-protected building block for the synthesis of head-to-tail cyclic peptides by Fmoc SPPS.The α-allyl ester can be selectively removed in the presence of Fmoc- and tBu-based protecting groups by treatment with Pd(Ph3P)4/ CHCl3/AcOH/NMM, thereby facilitating the synthesis of branched esters and amides, and lactones and lactams incorporating a glutamyl unit. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Glu-OAll, N-α-Fmoc-L-glutamic acid α-allyl ester. CAS No. 144120-54-7. Molecular formula: C23H23NO6. Mole weight: 409.43. Catalog: ACM144120547. | |
| Fmoc-Glu(OAll)-OH | Orthogonally-protected building block for the synthesis of peptides modified at the Glu side chain by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Glu(OAll)-OH. CAS No. 133464-46-7. Molecular formula: C23H23NO6. Mole weight: 409.43. Catalog: ACM133464467. | |
| Fmoc-Glu(OBzl)-OH | Building block for introduction of glutamic acid bearing TFA-labile benzyl ester side-chain protection. Benzyl group is removed by hydrogenation over Pd/C or with strong acids such as TFMSA. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Glu(OBzl)-OH, N-α-Fmoc-L-glutamic acid γ-benzyl ester. CAS No. 123639-61-2. Mole weight: 459.49. Catalog: ACM123639612. | |
| Fmoc-Glu-ODmab | Quasi-orthogonally-protected Glu derivative. The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF , making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS. or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Glu(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Glu-ODmab, N-α-Fmoc-L-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester. CAS No. 172611-75-5. Mole weight: 680.79. Catalog: ACM172611755. | |
| Fmoc-Glu-OtBu | Selectively protected building block for library synthesis or the preparation of γ-glutamyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the γ-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters, amides, lactams and lactones containing the glutamyl unit. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Glu-OtBu, N-α-Fmoc-L-glutamic acid α-t.-butyl ester. CAS No. 84793-07-7. Molecular formula: C24H27NO6. Mole weight: 425.47. Catalog: ACM84793077. | |
| Fmoc-Gly-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of glycine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Gly-OH, FMOC-Glycine, N-α-Fmoc-glycine. CAS No. 29022-11-5. Molecular formula: C17H15NO4. Mole weight: 297.31. Catalog: ACM29022115. | |
| Fmoc-gly-osu | Heterocyclic Organic Compound. CAS No. 113484-74-5. Molecular formula: C21H18N2O6. Mole weight: 394.38. Purity: 0.95. Catalog: ACM113484745. | |
| Fmoc-hArg(Pbf)-OH | Fmoc-homoArg(Pbf)-OH is a useful tool for the introduction of homoarginine during Fmoc SPPS. It can be used in exactly the same manner as Fmoc-Arg(Pbf)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-hArg(Pbf)-OH, N-α-Fmoc-N G-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-homoarginine. CAS No. 1159680-21-3. Molecular formula: C35H42N4O7S. Mole weight: 662.8. IUPACName: (2R) -6-[[amino-[ (2, 2, 4, 6, 7-pentamethyl-3H-1-benzofuran-5-yl) sulfonylamino]methylidene]amino]-2- (4b, 8a, 9, 9a-tetrahydro-4aH-fluoren-9-ylmethoxycarbonylamino) hexanoic acid. Canonical SMILES: CC1=C (C (=C (C2=C1OC (C2) (C)C)C)S (=O) (=O)NC (=NCCCCC (C (=O)O)NC (=O)OCC3C4C=CC=CC4C5C3C=CC=C5)N)C. Catalog: ACM1159680213. | |
| Fmoc-hCys(Trt)-OH | Fmoc-homoCys(Trt)-OH is a useful tool for the introduction of homocysteine during Fmoc SPPS. It can be used in exactly the same manner as Fmoc-Cys(Trt)-OH. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-hCys(Trt)-OH, Fmoc-S-trityl-L-homocysteine. CAS No. 167015-23-8. Molecular formula: C38H33NO4S. Mole weight: 599.74. Catalog: ACM167015238. | |
| Fmoc-hGlu(OtBu)-OH | A useful homolog of glutamic acid for the study of protein-protein interactions, tumor targeting, and SAR studies. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-hGlu(OtBu)-OH, Fmoc-L-α-homoglutamic acid 6-t-butyl ester,(S)-2-(Fmoc-amino)adipic acid 6-t-butyl ester. CAS No. 159751-47-0. Mole weight: 439.5. Catalog: ACM159751470. | |
| Fmoc-his(fmoc)-opfp | Heterocyclic Organic Compound. Alternative Names: FMOC-HISTIDINE(FMOC)-OPFP; FMOC-N-IM-FMOC-L-HISTIDINE PENTAFLUOROPHENYL ESTER. CAS No. 114616-10-3. Molecular formula: C42H28N3O6F5. Mole weight: 765.7. Purity: 0.96. IUPACName: 9H-fluoren-9-ylmethyl4-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxo-3-(2,3,4,5,6-pentafluorophenoxy)propyl]imidazole-1-carboxylate. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NC (CC4=CN (C=N4)C (=O)OCC5C6=CC=CC=C6C7=CC=CC=C57)C (=O)OC8=C (C (=C (C (=C8F)F)F)F)F. Catalog: ACM114616103. | |
| Fmoc-His(Trt)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of histidine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-His(Trt)-OH, N-α-Fmoc-N-im-trityl-L-histidine. CAS No. 109425-51-6. Molecular formula: C40H33N3O4. Mole weight: 619.71. Catalog: ACM109425516. | |
| Fmoc-homopropargylglycine | Building block for the introduction by Fmoc SPPS. of an amino acid bearing an alkyne side chain. Such derivatives are useful tools for the synthesis of cyclic peptides by an alkyne-alkyne Glaser coupling, involving Cu(OAc)2/pyridine and heating to 60 °Cusing microwaves. Uses: Fmoc-hpg-oh has a wide range of applications in scientific research. it can be used to synthesize peptides with desirable biological properties such as antimicrobial activity, anticancer activity, and enzyme inhibitory activity. these peptides can be used in drug discovery and development, as well as in the treatment of a wide range of diseases. Group: Amino acids. Alternative Names: Fmoc-homopropargylglycine. CAS No. 942518-21-0. Molecular formula: C21H19NO4. Mole weight: 349.38. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hex-5-ynoic acid. Canonical SMILES: C#CCCC (C (=O)O)NC (=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Density: 1.265±0.06 g/mL. Catalog: ACM942518210. | |
| Fmoc-hPhe-OH | Standard building block for introduction of homophenylalanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-hPhe-OH, Fmoc-homo-L-phenylalanine. CAS No. 132684-59-4. Molecular formula: C25H23NO4. Mole weight: 401.45. Catalog: ACM132684594. | |
| Fmoc-Hse(Trt)-OH | Building block which enables side-chain modification of homoserine serines by Fmoc SPPS. The Trt group can be removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This derivative has been employed to prepare oligonucleotide conjugates. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Hse(Trt)-OH, N-α-Fmoc-O-trityl-L-homoserine. CAS No. 111061-55-3. Mole weight: 583.67. Catalog: ACM111061553. | |
| Fmoc-Hyp-OH | Building block for introduction of hydroxyproline amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Hyp-OH, N-α-Fmoc-L-trans-4-hydroxyproline. CAS No. 88050-17-3. Mole weight: 353.37. Catalog: ACM88050173. | |
| Fmoc-Hyp(tBu)-OH | Standard building block for introduction of hydroxyproline amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Hyp(tBu)-OH, N-α-Fmoc-O-t.-butyl-L-trans-4-hydroxyproline, Fmoc-(2S,4R)-(-)-4-t-butoxypyrrolidine-2-carboxylic acid. CAS No. 122996-47-8. Molecular formula: C24H27NO5. Mole weight: 409.47. Catalog: ACM122996478. | |
| Fmoc-Ile-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of isoleucine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Ile-OH, N-α-Fmoc-L-isoleucine. CAS No. 71989-23-6. Molecular formula: C21H23NO4. Mole weight: 353.41. Catalog: ACM71989236. | |
| Fmoc-iminodiacetic acid | Heterocyclic Organic Compound. Alternative Names: 112918-82-8, ACMC-20akus, Fmoc-iminodiacetic acid, SureCN6745317, CTK4A8036, AKOS015837154, AG-D-32448, N- (9-Fluorenylmethoxycarbonyl) iminodiaceticacid, I04-3777, Glycine,N-(carboxymethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-. CAS No. 112918-82-8. Molecular formula: C19H17NO6. Mole weight: 355.35. Purity: 0.95. IUPACName: 2-(carboxymethylamino)-3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoic acid. Density: 1.41g/cm³. Catalog: ACM112918828. | |
| Fmoc-Isn-OH | Standard building block for introduction of isonipecotic acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Isn-OH, N-α-Fmoc-piperidine-4-carboxylic acid, Fmoc-Inp-OH. CAS No. 148928-15-8. Mole weight: 351.4. Catalog: ACM148928158-1. | |
| Fmoc-L-(2,6-di-Me)Tyr-OH | Fmoc-2,6-dimethyl-L-tyrosine is a derivative of L-tyrosine, which is one of the 20 naturally occurring amino acids. It is an acronym for 9-Fluorenylmethyloxycarbonyl-2,6-dimethyltyrosine. Fmoc-2,6-dimethyl-L-tyrosine is also referred to as fluorenylmethoxycarbonyl-2,6-dimethyltyrosine or Fmoc-Dmt-OH. Fmoc-Dmt-OH has a molecular weight of 393.45 and a molecular formula of C23H21NO5. Uses: Fmoc-2,6-dimethyl-l-tyrosine has several research applications, including the synthesis of peptides, proteins, and peptidomimetics. it is also used as a building block of combinatorial libraries for the discovery of new drug candidates. fmoc-2,6-dimethyl-l-tyrosine has been incorporated into various bioactive peptides and proteins to improve their stability, activity, and specificity. it has also been used as a precursor for the synthesis of novel peptidomimetics with potential therapeutic applications. Group: Amino acids. Alternative Names: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2,6-dimethyl-L-tyrosine, Fmoc-2,6-dimethyl-L-tyrosine, (S)-N-Fmoc-2,6-Dimethyltyrosine. CAS No. 206060-54-0. Molecular formula: C26H25NO5. Mole weight: 431.5. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-hydroxy-2,6-dimethylphenyl)propanoic acid. Canonical SMILES: CC1=CC (=CC (=C1CC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)C)O. Density: 1.290 g/cm3. Catalog: ACM206060540. | |
| Fmoc-L-cysteic acid | Fmoc-L-cysteic acid is an Fmoc protected cysteine derivative potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function. Uses: Fmoc-l-cysteic acid is an fmoc protected cysteine derivative. Group: Amino acids. Alternative Names: (2R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-sulfopropanoic acid. CAS No. 751470-47-0. Molecular formula: C18H17NO7S. Mole weight: 391.4. Purity: ≥ 98% (HPLC). Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)N[C@@H] (CS (=O) (=O)O)C (=O)O. Density: ~1.50 g/cm3. Catalog: ACM751470470. | |
| Fmoc-Leu-Ser(psiMe,Mepro)-OH | This pseudoproline dipeptide is undoubtedly the most effective and simplest to use tool for overcoming aggregation and enhancing peptide quality in Fmoc SPPS for peptide containing the Leu-Ser dipeptide motif. It consists of a dipeptide in which the serine residue has been reversibly protected as a structure-breaking proline-like TFA-labile oxazolidine. The reason the pseudoproline residue is introduced as a dipeptide is because it avoids the need to acylate the hindered oxazolidine nitrogen. This has the added advantage of extending the peptide chain by two residues in one step. The serine residue is regenerated during the normal TFA-mediated cleavage reaction. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Leu-Ser(psiMe,Mepro)-OH. CAS No. 339531-50-9. Mole weight: 480.55. Catalog: ACM339531509. | |
| Fmoc-L-selenomethionine | Fmoc-selenomethionine can be introduced under standard conditions. Any selenoxide formed during synthesis can be easily reduced back to selenide by treatment with β-mercaptoethanol. Introduction of selenium can help facilitate solid phase and solution structural determination and the study of peptide-protein interactions. Uses: Fmoc solid-phase peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-selenomethionine, N-Fmoc-L-amino-4-(methylselanyl)butanoic acid. CAS No. 1217852-49-7. Molecular formula: C20H21NO4Se. Mole weight: 418.4. Purity: Peak Area by HPLC ≥95%. Catalog: ACM1217852497. | |
| Fmoc-Lys(4,5-dimethoxy-2-nitro-benzyloxycarbonyl)-OH | Fmoc-L-Lys(Nvoc)-OH is a lysine derivative compatible with solid-phase peptide synthesis (SPPS). Uses: Photocaged amino acids such as these are useful in the synthesis of photocleavable chemical tools for spatial and temporal control over released molecules in biological applications. Group: Amino acids. Alternative Names: (S) -2- ( ( (9H-Fluoren-9-yl) methoxy) carbonylamino) -6- ( (4, 5-dimethoxy-2-nitrobenzyloxy) carbonylamino) hexanoic acid, N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N6-(((4,5-dimethoxy-2-nitrobenzyl)oxy)carbonyl)-L-lysine, Lysine with photoremovable NVOC, Photocaged amino acid, Photocleavable lysine derivative. CAS No. 150571-28-1. Molecular formula: C31H33N3O10. Mole weight: 607.6. IUPACName: (2S) -6-[ (4, 5-dimethoxy-2-nitrophenyl) methoxycarbonylamino]-2- (9H-fluoren-9-ylmethoxycarbonylamino) hexanoic acid. Canonical SMILES: COC1=C (C=C (C (=C1)COC (=O)NCCCCC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)[N+] (=O)[O-])OC. Density: 1.326±0.06 g/cm3. Catalog: ACM150571281. | |
| Fmoc-Lys(5-FAM)-OH | FMOC-Lys(5-FAM)-OH is a building block for in-sequence Lysine labeling by FAM. FAM is a commonly used donor dye for preparing FRET peptides. Uses: Peptide synthesis. Group: Amino acids. CAS No. 1242933-88-5. Molecular formula: C42H34N2O10. Mole weight: 726.7. Purity: Peak Area by HPLC ≥90%. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)N[C@@H] (CCCCNC (=O)C4=CC5=C (C=C4)C6 (C7=C (C=C (C=C7)O)OC8=C6C=CC (=C8)O)OC5=O)C (=O)O. Catalog: ACM1242933885. | |
| Fmoc-Lys(Alloc)-OH | Orthogonally-protected building block for the synthesis of branched and cyclic peptides and peptides modified at the Lys side chain by Fmoc SPPS. The Alloc group can be selectively removed in the presence of standard Fmoc- and t-butyl-based protecting groups by treatment with Pd(Ph3P)4/CHCl3/AcOH/NMM. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Nα-Fmoc-Nε-Alloc-L-lysine. CAS No. 146982-27-6. Molecular formula: C25H28N2O6. Mole weight: 452.5. Canonical SMILES: OC (=O)[C@H] (CCCCNC (=O)OCC=C)NC (=O)OCC1c2ccccc2-c3ccccc13. Catalog: ACM146982276. | |
| Fmoc-Lys(biotin)-OH | A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(biotin)-OH, N-α-Fmoc-N-ε-biotinyl-L-lysine. CAS No. 146987-10-2. Molecular formula: C31H38N4O6S. Mole weight: 594.72. Purity: Peak Area by HPLC ≥90%. Canonical SMILES: C1C2C (C (S1)CCCCC (=O)NCCCCC (C (=O)O)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)NC (=O)N2. Density: 1.3±0.1 g/cm3. Catalog: ACM146987102. | |
| Fmoc-lys(boc)-bt | Heterocyclic Organic Compound. Alternative Names: 1126433-45-1, Fmoc-Lys(Boc)-Bt, AKOS015950334, RP08122, FT-0685701, tert-butyl N-[(5S)-6-(1,2,3-benzotriazol-1-yl)-5-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-6-oxohexyl]carbamate. CAS No. 1126433-45-1. Molecular formula: C32H35N5O5. Mole weight: 569.67. Purity: 0.96. IUPACName: tert-butyl N-[(5S)-6-(benzotriazol-1-yl)-5-(9H-fluoren-9-ylmethoxycarbonylamino)-6-oxohexyl]carbamate. Canonical SMILES: CC (C) (C)OC (=O)NCCCCC (C (=O)N1C2=CC=CC=C2N=N1)NC (=O)OCC3C4=CC=CC=C4C5=CC=CC=C35. Catalog: ACM1126433451. | |
| Fmoc-Lys(Boc)-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of lysine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Boc)-OH, N-α-Fmoc-N-ε-t.-Boc-L-lysine. CAS No. 71989-26-9. Molecular formula: C26H32N2O6. Mole weight: 468.54. Catalog: ACM71989269. | |
| Fmoc-Lys(Boc)-OH (1-13C) | L-Lysine N-Fmoc/Boc (1-13C) is a protected amino acid used to synthesize isotope-labeled peptides for MS-based protein quantitation. Uses: Biomolecular nmr, proteomics. Group: Amino acids. Alternative Names: N-α-Fluorenylmethoxycarbonyl-N-ε-tert-butoxycarbonyl-L-lysine. CAS No. 1242058-72-5. Molecular formula: Boc-NH(CH2)4CH(NH-Fmoc)13COOH. Mole weight: 469.5. Purity: Peak Area by HPLC ≥95%. ECNumber: 276-256-4 (Unlabeled). Catalog: ACM1242058725-1. | |
| Fmoc-Lys(Dde)-OH | Quasi-orthogonally-protected Lys derivative for Fmoc SPPS. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF. When removing Dde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Lys(Dde) has been employed in the following applications: synthesis of branched peptides and di-epitopic peptides ; preparation of MAP core molecules and lipo-MAPs; construction of cyclic peptides , TASP molecules , templates for combinatorial chemistry and synthetic proteins ; preparation of peptides modified at the lysine side-chain.It has been reported that Dde can migrate from the side-chain of Lys to the unprotected side-chain of another Lys residue , and from the β-amino group to the α-amino group of Dpr. In the former instance, this problem can be overcome by using Fmoc-Lys(ivDde)-OH or using DBU/DMF (2:98) for Fmoc group removal.Full orthogonality of Dde with Fmoc has recently been demonstrated when hydroxylamine is used for Dde removal. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Dde)-OH, N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine. CAS No. 150629-67-7. Molecular formula: C31H36N2O6. Mole weight: 532.63. Catalog: ACM150629677. | |
| Fmoc-Lys(Fmoc)-OH | Useful derivative for the synthesis of branched peptides. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Fmoc)-OH, N-α,ε-di-Fmoc-L-lysine. CAS No. 78081-87-5. Molecular formula: C36H34N2O6. Mole weight: 590.66. Catalog: ACM78081875. | |
| Fmoc-Lys(ivDde)-OH | This orthogonally-protected lysine derivative is based on the hindered Dde variant ivDde. It has very similar chemical properties to Fmoc-Lys(Dde)-OH, except that the side-chain ivDde group is considerably more stable to piperidine than Dde, and is less prone to migrate from protected to unprotected lysine side-chains.When removing ivDde in the presence of allyl based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(ivDde)-OH, N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-lysine. CAS No. 204777-78-6. Molecular formula: C34H42N2O6. Mole weight: 574.71. IUPACName: (2S)-6-[[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid. Canonical SMILES: CC (C)CC (=C1C (=O)CC (CC1=O) (C)C)NCCCCC (C (=O)O)NC (=O)OCC2C3=CC=CC=C3C4=CC=CC=C24. Density: 1.2±0.1 g/cm3. Catalog: ACM204777786. | |
| Fmoc-Lys(Me)2-OH · HCl | A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Me)2-OH HCl, N-α-Fmoc-N-ε-dimethyl-N-L-lysine · hydrochloride. CAS No. 252049-10-8. Molecular formula: C23H28N2O4·HCl. Mole weight: 396.4·36.5. Catalog: ACM252049108. | |
| Fmoc-Lys(Me3Cl)-OH | A novel derivative for the introduction of trimethyl-lysine during Fmoc SPPS. Ref contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Me3Cl)-OH, N-α-Fmoc-N-ε-trimethyl-N-L-lysine · chloride. CAS No. 201004-29-7. Molecular formula: C24H31ClN2O4. Mole weight: 446.97. Catalog: ACM201004297. | |
| Fmoc-Lys(Me, Boc)-OH | Fmoc-lys(ME,boc)-OH is a chemical compound composed of 2,2-dimethyl-4,6-dioxoheptanoic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, (S)-4-amino-6-((1,1-dimethylethoxy)carbonyl)hexanoic acid, which is commonly referred to as Fmoc-Lys(ME,Boc)-OH. This compound belongs to the family of Fmoc-amino acids, which are widely used as building blocks in peptide synthesis. Uses: Fmoc-lys(me,boc)-oh is widely used as a building block in peptide synthesis, including the synthesis of cyclic peptides, stapled peptides, and peptidomimetics. it is also used in the development of drugs and pharmaceuticals. Group: Amino acids. Alternative Names: Fmoc-Lys(Me,Boc)-OH, N-α-Fmoc-N-ε-methyl-N-ε-t.-Boc-L-lysine. CAS No. 951695-85-5. Molecular formula: C27H34N2O6. Mole weight: 482.6. IUPACName: (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoic acid. Canonical SMILES: CC (C) (C)OC (=O)N (C)CCCCC (C (=O)O)NC (=O)OCC1C2=CC=CC=C2C3=CC=CC=C13. Density: 1.2±0.1 g/cm3. Catalog: ACM951695855. | |
| Fmoc-Lys(Mtt)-OH | The side-chain Mtt group can be selectively removed with 1% TFA in DCM or DCM/HFIP/TFE/TES (6.5:2:1:0.5) , making this an excellent derivative for the synthesis by Fmoc SPPS. of branched peptides, peptides modified at the lysine side-chain , for the construction of templates and multifunctionalized resins for combinatorial synthesis. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Mtt)-OH, N-α-Fmoc-N-ε-4-methyltrityl-L-lysine. CAS No. 167393-62-6. Molecular formula: C41H40N2O4. Mole weight: 624.77. Catalog: ACM167393626. | |
| Fmoc-Lys(Tfa)-OH | Building block for introduction of lysine amino-acid residues bearing orthogonal side-chain protection. The trifluoroacetyl group can be selectively removed by aqueous basic hydrolysis. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Tfa)-OH, N-α-Fmoc-N-ε-trifluoroacetyl-L-lysine. CAS No. 76265-69-5. Mole weight: 464.43. Catalog: ACM76265695. | |
| Fmoc-Lys(Z)-OH | Building block for introduction of lysine amino-acid residues by Fmoc SPPS. The side-chain protecting group is TFA-stable but can be removed by hydrogenation over Pd/C or with strong acids such as TFMSA. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Lys(Z)-OH, N-α-Fmoc-N-ε-benzyloxycarbonyl-L-lysine. CAS No. 86060-82-4. Mole weight: 502.56. Catalog: ACM86060824. | |
| Fmoc-Met-OH | High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities. Standard building block for introduction of methionine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Met-OH, N-α-Fmoc-L-methionine. CAS No. 71989-28-1. Molecular formula: C20H21NO4S. Mole weight: 371.45. Catalog: ACM71989281. | |
| Fmoc-Met(O?)-OH | Standard building block for introduction of methionine sulfone residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Met(O2)-OH, N-α-Fmoc-L-methionine-sulfone. CAS No. 163437-14-7. Mole weight: 403.45. Catalog: ACM163437147. | |
| Fmoc-Met(O)-OH | Standard building block for introduction of methionine sulfoxide amino-acid residues by Fmoc SPPS. Uses: Fmoc-met(o)-oh novabiochem®. cas 76265-70-8, molar mass 387.45 g/mol. Group: Amino acids. Alternative Names: Fmoc-Met(O)-OH, N-α-Fmoc-L-methionine-DL-sulfoxide. CAS No. 76265-70-8. Molecular formula: C20H21NO5S. Mole weight: 387.45. Catalog: ACM76265708. | |
| Fmoc-Nalpha-Me-Arg(Mtr)-OH | Fmoc-n-me-arg(mtr)-oh belongs to the family of arginine derivatives and is commonly used as a building block in peptide synthesis. The compound is composed of an Fmoc (9-fluorenylmethyloxycarbonyl) protective group, an arginine residue, and an mtr (4-methoxy-2,3,6-trimethylbenzenesulfonyl) protective group. Uses: Fmoc-n-me-arg(mtr)-oh has a variety of applications in scientific experiments, including peptide synthesis, drug discovery, and biological assays. Group: Amino acids. Alternative Names: Fmoc-n-me-arg(mtr)-OH, (S) -2- ( ( ( (9H-Fluoren-9-yl) methoxy) carbonyl) (methyl) amino) -5- (3- ( (4-methoxy-2, 3, 6-trimethylphenyl) sulfonyl) guanidino) pentanoicacid, FMOC-N-ME-ARG-OH. CAS No. 214750-72-8. Molecular formula: C32H38N4O7S. Mole weight: 622.7. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S) -5- [ [amino- [ (4-methoxy-2, 3, 6-trimethylphenyl) sulfonylamino]methylidene]amino]-2- [9H-fluoren-9-ylmethoxycarbonyl (methyl) amino]pentanoic acid. Canonical SMILES: CC1=CC (=C (C (=C1S (=O) (=O) NC (=NCCCC (C (=O) O) N (C) C (=O) OCC2C3=CC=CC=C3C4=CC=CC=C24) N) C) C) OC. Catalog: ACM214750728. | |
| Fmoc-Nalpha-methyl-N-im-trityl-L-histidine | Fmoc-nalpha-methyl-n-im-trityl-l-histidine (FMOC-His(Trt)-OH) is a derivative of the amino acid Histidine. It is used as a building block for the synthesis of peptides and proteins. Histidine is a non-polar, essential amino acid involved in many biological processes such as the biosynthesis of proteins, metal ion binding, and catalysis in enzyme reactions. FMOC-His(Trt)-OH contains a 9-fluorenylmethyloxycarbonyl (Fmoc) protecting group on the amino terminus and a trityl (Trt) protecting group on the imidazole nitrogen. Uses: Fmoc-his(trt)-oh is mainly used as a starting material for the synthesis of peptides and proteins. it is used in spps for the incorporation of histidine residues in the peptide sequence. the resulting peptides and proteins have various applications in scientific experiments, including drug discovery and development, vaccine development, and biological research. Group: Amino acids. Alternative Names: FMOC-His(Trt)-OH. CAS No. 1217840-61-3. Molecular formula: C41H35N3O4. Mole weight: 633.7. Purity: Peak Area by HPLC ≥95%. IUPACName: (2S)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]-3-(1-tritylimidazol-4-yl)propanoic acid. Canonical SMILES: CN (C (CC1=CN (C=N1)C (C2=CC=CC=C2) (C3=CC=CC=C3)C4=CC=CC=C4)C (=O)O)C (=O)OCC5C6=CC=CC=C6C7=CC=CC=C57. Density: 1.2±0.1 g/cm3. Catalog: ACM1217840613. | |
| Fmoc-NH-PEG4-CH2COOH | Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Group: Fmoc peg linkers. Alternative Names: 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid. CAS No. 437655-95-3. Molecular formula: C25H31NO8. Mole weight: 473.5. Appearance: Liquid. Purity: >90%. IUPACName: 2-[2-[2-[2-[2- (9H-Fluoren-9-ylmethoxycarbonylamino) ethoxy]ethoxy]ethoxy]ethoxy]acetic acid. Canonical SMILES: C1=CC=C2C (=C1)C (C3=CC=CC=C32)COC (=O)NCCOCCOCCOCCOCC (=O)O. Density: 1.235±0.06 g/cm3. Catalog: ACM437655953. | |
| Fmoc-Nle-OH | Standard building block for introduction of norleucine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-Nle-OH, N-α-Fmoc-L-norleucine. CAS No. 77284-32-3. Molecular formula: C21H23NO4. Mole weight: 353.41. Catalog: ACM77284323. | |
| Fmoc-N-Me-Ala-OH | Building block for introduction of N-α-methyl-alanine amino-acid residues by Fmoc SPPS. Uses: Peptide synthesis. Group: Amino acids. Alternative Names: Fmoc-N-Me-Ala-OH, N-α-Fmoc-N-α-methyl-L-alanine. CAS No. 84000-07-7. Mole weight: 325.36. Catalog: ACM84000077. | |
| Fmoc-N-Me-Cys(Trt)-OH | Building block for introduction of N-α-methyl-cysteine amino-acid residues by Fmoc SPPS. Fmoc SPPS of Cysteine-Containing Peptides. Uses: Fmoc-n-me-cys(trt)-oh is a fmoc-protected derivative of n-methyl cysteine used as a building block to prepare peptide thioesters under acidic conditions. the residue attached to the amino group of n-methylcysteine can migrate to the cysteinyl thiol group, resulting in the formation of a peptide thioester. the introduction of this fmoc-protected derivative is best achieved using hatu as a coupling reagent in the presence of dipea (n, n-diisopropylethylamine). it can also be used to prepare fmoc-n-me-cys(trt)-oallyl intermediate for the solid-phase synthesis of dithiol triostin a. Group: Amino acids. Alternative Names: N-α-Fmoc-N-α-methyl-S-trityl-L-cysteine. CAS No. 944797-51-7. Mole weight: 599.74. Catalog: ACM944797517. | |
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