BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 1-Acetyl-4-methylpiperazine hydrochloride | 1-Acetyl-4-methylpiperazine hydrochloride is the hydrochloride salt of 1-Acetyl-4-methylpiperazine which is a structural analog of acetylcholine. It acts as a nicotinic agonist. It is used in the preparation of pyrrolopyrazinium iodides and (acetyl)piperazinium iodide. Synonyms: 1-(4-methylpiperazin-1-yl)ethanone hydrochloride. CAS No. 144205-68-5. Molecular formula: C7H15N2OCl. Mole weight: 178.66. |  |
| 1α, 24, 25-Trihydroxy VD2 | 1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog. Synonyms: 1alpha, 24, 25-Trihydroxy VD2; 457048-34-9; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R)-5,6-dihydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol; 1Alpha,24,25-Trihydroxy VD2; CS-0807; DTXSID80569509; AKOS025401836; AC-26343; HY-15156; MS-28018; PD101542; F84843; (1S,3R,5Z,7E,22E,24xi)-9,10-Secoergosta-5,7,10,22-tetraene-1,3,24,25-tetrol. Grades: >98%. CAS No. 457048-34-9. Molecular formula: C28H44O4. Mole weight: 444.65. | |
| 1-Arachidonoyl glycerol | The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. Synonyms: 1-AG; glyceryl 1-arachidonate. Grades: ≥95%. CAS No. 35474-99-8. Molecular formula: C23H38O4. Mole weight: 378.6. | |
| 1-Deazaadenosine | 1-Deazaadenosine is an adenosine deaminase inhibitor and has been found to show antitumor activity in some leukemia cell lines. Synonyms: 3-β-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine. Grades: ≥98% by HPLC. CAS No. 14432-09-8. Molecular formula: C11H14N4O4. Mole weight: 266.25. | |
| 1-Decanoyl-rac-glycerol | 1-Decanoyl-rac-glycerol is a monoacylglyecrol with antibacterial activity. Studies show that 1-Decanoyl-rac-glycerol may be potential apoptotic agents in T-cells. Synonyms: 2,3-Dihydroxypropyl decanoate; 1-Monocaprin; 1-Monodecanoin. Grades: ≥98%. CAS No. 2277-23-8. Molecular formula: C13H26O4. Mole weight: 246.34. | |
| 1-Docosanol | Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. Synonyms: docosan-1-ol. Grades: > 98 %. CAS No. 661-19-8. Molecular formula: C22H46O. Mole weight: 326.60. | |
| (1E,6E)-Demethoxycurcumin | Natural demethoxy curcuminoid. Anticancer, antiproliferative and antioxidant activity. Inhibits various signaling pathways including Wnt/β-catenin, AMPK and MAPK. Uses: Antitumor, fight free radicals and lipid. Synonyms: (1E,6E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione; 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (E,E)-; 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(p-hydroxyphenyl)-; (1E,6E)-1-(4-Hydroxyphenyl)-7-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; Curcumin II; Demethoxycurcumin; Desmethoxycurcumin; Monodemethoxycurcumin; 1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, (1E,6E)-. Grades: >98%. CAS No. 22608-11-3. Molecular formula: C20H18O5. Mole weight: 338.35. | |
| 1-Linoleoyl glycerol | Platelet-activating factor (PAF) is a biologically active phospholipid synthesized by a variety of stimulated cells that acts as a mediator of platelet aggregation, inflammation, and allergy. 1-Linoleyl glyceride acts as a free-living amoeba control agent, also a biomarker of metabolic responses to hepatotoxicants and carcinogens. Synonyms: 1-LG; Glycerol 1-monolinolate; 1-Monolinolein; Glyceryl linoleate. Grades: ≥90%. CAS No. 2277-28-3. Molecular formula: C21H38O4. Mole weight: 354.5. | |
| 1-Methylpsilocin | 1-Methylpsilocin is a potent and selective 5-HT2C agonist (IC50= 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). It is acting at 5-HT2A sites but is inactive at the 5-HT1A receptor.\. Synonyms: 3-[2-(Dimethylamino)ethyl]-1-methylindol-4-ol. Grades: ≥99% by HPLC. CAS No. 1465-16-3. Molecular formula: C13H18N2O. Mole weight: 218.29. | |
| 1-Naphthyl 3,5-dinitrobenzoate | 1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 μM, respectively. Synonyms: 1-(3,5-Dinitrobenzoyloxy)naphthalene; 1-Naphthalonol 3,5-dinitrobenzoate. Grades: ≥98%. CAS No. 93261-39-3. Molecular formula: C17H10N2O6. Mole weight: 338.3. | |
| 1-Naphthyl PP1 hydrochloride | 1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases, including v-Src and c-Fyn, tyrosine kinase c-Abl and CAMK II with IC50 values of 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively. It was considerably more potent and showed distinct substituent effects at the pyrazolopyrimidine core. It was cell-active, and potently blocked prostate cancer cell proliferation by inducing G2/M arrest. Uses: 1-naphthyl pp1 hydrochloride could potently block prostate cancer cell proliferation by inducing g2/m arrest. Synonyms: 1-Tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride;1-NA-PP 1 hydrochloride. Grades: >98 %. CAS No. 956025-47-1. Molecular formula: C19H20ClN5. Mole weight: 353.85. | |
| 1-NM-PP1 | 1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28 μM, respectively). Synonyms: 1NM-PP1; 1NM PP1; 1NMPP1l PP1 analog II. CAS No. 221244-14-0. Molecular formula: C20H21N5. Mole weight: 331.41424. | |
| 1-Oleoyl-2-acetyl-sn-glycerol | 1-Oleoyl-2-acetyl-sn-glycerol is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. Activator of phospholipid-dependent protein kinase C and stimulator of secretion and aggregation in blood platelets. Synonyms: 18:1-2:0 DG; 1-(9Z-octadecenoyl)-2-acetoyl-sn-glycerol; DG(18:1(9Z)/2:0/0:0); OAG; 2-Acetyl-1-oleoyl-sn-glycerol; 1-O-Octadecenoyl-2-O-acetylglycerol. Grades: ≥90%. CAS No. 86390-77-4. Molecular formula: C23H42O5. Mole weight: 398.58. | |
| 1-Palmitoyl-d9-2-Palmitoyl-sn-glycerol | 1-Palmitoyl-d9-2-palmitoyl-sn-glycerol is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycerol by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycerol is a diacylglycerol that contains palmitic acid at the sn-1 and sn-2 positions. It activates protein kinase C (PKC) by 15% when used at a concentration of 25 μM. Synonyms: 1,2-Dipalmitoyl-sn-glycerol-d9; DG(16:0-d9/16:0/0:0). Grades: ≥99% atom D. CAS No. 1872379-48-0. Molecular formula: C35H59D9O5. Mole weight: 578. | |
| 1-Perillaldehyde α-antioxime | Perillartine, the a-syn-oxime 1 of perillaldehyde, is a sweetening agent which activates the taste receptor type 1 member 2 (Tas1r2) subunit in a species-dependent manner. Synonyms: AI3-52127; AI3 52127; AI352127; (NE)-N-[(4-prop-1-en-2-ylcyclohexen-1-yl)methylidene]hydroxylamine; perillartine; perillartine, (E)-(+)-isomer; perillartine, (E)-(+-)-isomer; perillartine, (E)-(-)-isomer; perillartine, (E)-isomer; perillartine, (S)-isomer. Grades: >98%. CAS No. 30950-27-7. Molecular formula: C10H15NO. Mole weight: 165.23. | |
| 1-Phenylbiguanide hydrochloride | 1-Phenylbiguanide hydrochloride is a 5-HT3 receptor agonist. Synonyms: 1-(diaminomethylidene)-2-phenylguanidine;hydrochloride. CAS No. 55-57-2. Molecular formula: C8H12ClN5. Mole weight: 213.67. | |
| (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 | (1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a selective and potent somatostatin sst2 receptor agonist with Ki value of 4nm. Its Ki values are 537, 3614, 2480 and 5017 nM for cloned human sst1, sst3, sst4 and sst5 receptors respectively. Synonyms: N-[ (1R) -2-[[[ (1S*, 3R*) -3- (Aminomethyl) cyclohexyl]methyl]amino]-1- (1H-indol-3-ylmethyl) -2-oxoethyl]spiro[1H-indene-1, 4'-piperidine]-1'-carboxamide. Grades: ≥96% by HPLC. CAS No. 208706-12-1. Molecular formula: C33H41N5O2. Mole weight: 539.71. | |
| (1R,2S)-VU0155041 | (1R,2S)-VU0155041 is a partial mGluR4-positive allosteric modulator (EC50 = 2.35 μM) that dependently attenuated hyperalgesia in neuropathic pain model rats. Synonyms: (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid; VU 0155041; VU-0155041; VU0155041. CAS No. 1263273-14-8. Molecular formula: C14H15Cl2NO3. Mole weight: 316.18. | |
| (1S,3R)-ACPD | (1S,3R)-ACPD, an isomer of (±)-trans-ACPD, has been found to be an agonist of mGluRs. Synonyms: 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S,3R)-; (1S,3R)-1-Amino-1,3-cyclopentanedicarboxylic acid; 1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S-cis)-; 1-Amino-trans-1,3-cyclopentanedicarboxylic acid; 1-Amino-trans-1,3-dicarboxycyclopentane; 1-Aminocyclopentane-1S,3R-dicarboxylic acid; ACPD; cis-1-Amino-1,3-dicarboxycyclopentane; trans-ACPD. Grades: ≥98% by HPLC. CAS No. 111900-32-4. Molecular formula: C7H11NO4. Mole weight: 173.17. | |
| 1-Stearoyl-2-Arachidonoyl-sn-glycerol | 1-Stearoyl-2-arachidonoyl-sn-glycerol activates PKC allosterically. It activates transient receptor potential channels 3 and 6 that regulates the intracellular free calcium levels. Synonyms: 18:0-20:4 DG; 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol; DG(18:0/20:4(5Z,8Z,11Z,14Z)/0:0). Grades: >99%. CAS No. 65914-84-3. Molecular formula: C41H72O5. Mole weight: 645.01. | |
| 20-Carboxy arachidonic acid | 20-Carboxy arachidonic acid (20-COOH-AA) is the major metabolite of 20-HETE that is produced in renal tubular epithelial, endothelial, and microvascular smooth muscle cell cultures. This ω-oxidation conversion can take place using purified alcohol dehydrogenases three and four or by microsomes containing recombinant human CYP4F3B. Synonyms: 20-carboxy AA; 20-COOH-AA; 5Z,8Z,11Z,14Z-Eicosatetraenedioic acid; Arachidonic acid-20-carboxylic acid. Grades: >98%. CAS No. 79551-84-1. Molecular formula: C20H30O4. Mole weight: 334.5. | |
| 20-Ethyl prostaglandin F2α | 20-Ethyl prostaglandin F2α (20-ethyl PGF2α) is an analog of PGF2α in which the ω-chain has been extended by the addition of two more methylene carbon atoms. It is therefore a modified version of the clinically approved glaucoma medication unoprostone. Synonyms: ICI 74205; 20-ethyl PGF2α; 20-Ethyl-pgf2-alpha. Grades: ≥98%. CAS No. 36950-85-3. Molecular formula: C22H38O5. Mole weight: 382.5. | |
| 20-HEPE | 20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. Grades: ≥95%. CAS No. 116477-57-7. Molecular formula: C20H30O3. Mole weight: 318.5. | |
| 20(R)-Protopanaxatriol | Protopanaxatriol is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng). It may have a beneficial effect on cancer chemotherapy with respect to the possibility of long-term use witho. Synonyms: (20R)-Dammar-24-ene-3β, 6α, 12β, 20-tetrol;(20R)-5α-Dammar-24-ene-3β, 6α, 12β, 20-tetrol;(20R)-Protopanaxatriol;(3β, 6α, 12β, 20R)-Dammar-24-ene-3, 6, 12, 20-tetrol. Grades: >98%. CAS No. 1453-93-6. Molecular formula: C30H52O4. Mole weight: 476.73. | |
| 20(S)-Notoginsenoside R2 | The neuroprotection elicited by Notoginsenoside R2 against 6-OHDA-induced neurotoxicity was associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways. Uses: 20(s)-notoginsenoside r2 has neuroprotection against 6-ohda-induced neurotoxicity. Synonyms: (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl 2-O-beta-D-xylopyranosyl-beta-D-glucopyranoside. Grades: >98%. CAS No. 80418-25-3. Molecular formula: C41H70O13. Mole weight: 770.99. | |
| (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol | 2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. 2-(14,15-Epoxyeicosatrienoyl) Glycerol (2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. 2-14,15-EG is a potent mitogen for renal epithelial cells. Synonyms: (±)2-14,15-EG; 2-(14,15-epoxyeicosatrienoyl)glycerol; 1,3-dihydroxypropan-2-yl 13-(3-pentyloxiran-2-yl)trideca-2,4,6-trienoate. Grades: ≥95%. CAS No. 848667-56-1. Molecular formula: C23H38O5. Mole weight: 394.5. | |
| 2-(1-Benzyl-1H-indazol-3-yloxy)acetic Acid | Bendazac is a non-steroidal anti-inflammatory drug (NSAID) used for joint and muscular pain, which is also known as AF-983 (an anticataract drug). It was found to inhibit only reversible and irreversible xanthine oxidase. Bendazac also inhibits the denaturing of proteins. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 2-[[1-(phenylmethyl)-3-indazolyl]oxy]acetic acid; 2-(1-benzylindazol-3-yl)oxyacetic acid. Grades: ≥ 98 %. CAS No. 20187-55-7. Molecular formula: C16H14N2O3. Mole weight: 282.29. | |
| 2-(2-Aminoethyl)isothiourea dihydrobromide | 2-(2-Aminoethyl)isothiourea dihydrobromide is a pan-inhibitor of all NOS isoforms with Kis of 1.8, 2.1, and 0.59 μM for human nNOS, eNOS, and iNOS, respectively. Uses: Radiation-protective agents. Synonyms: Carbamimidothioic acid, 2-aminoethyl ester, hydrobromide (1:2); Carbamimidothioic acid, 2-aminoethyl ester, dihydrobromide; Pseudourea, 2-(2-aminoethyl)-2-thio-, dihydrobromide; 2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide; 2-(2-Aminoethyl)-2-thiopseudourea hydrobromide; 2-(β-Aminoethyl)isothiuronium bromide hydrobromide; AET; Antiradon; Ixecur; NSC 22877; S-(2-Aminoethyl)isothiuronium bromide hydrobromide; S-(β-Aminoethyl)isothiuronium bromide hydrobromide; Surrectan; S-(2-aminoethyl) Isothiourea dihydrobromide. Grades: 95%. CAS No. 56-10-0. Molecular formula: C3H11Br2N3S. Mole weight: 281.01. | |
| 22(S)-Hydroxy cholesterol | 22(S)-Hydroxy cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). Synonyms: cholest-5-ene-3β,22(S)-diol; 22(S)-Hydroxycholesterol; 5-cholestene-3β,22-diol; 22-hydroxycholest-5-en-3-ol; 22β-Hydroxy Cholesterol; (3β,22S)-Cholest-5-ene-3,22-diol; (20S,22S)-Cholest-5-ene-3β,22-diol; (22S)-22-Hydroxycholesterol; (22S)-Cholest-5-ene-3β,22-diol; (22β)-Hydroxycholesterol; Narthesterol. Grades: ≥95%. CAS No. 22348-64-7. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| 2-(3,3-Diphenylpropylamino)-N,N-Diphenylacetamide Hydrochloride | N 20C hydrochloride is a non-competitive NMDA glutamate receptor antagonist. Synonyms: 2-(3,3-Diphenylpropylamino)-N,N-diphenylacetamide hydrochloride. Grades: 98%. CAS No. 928313-94-4. Molecular formula: C29H29ClN2O. Mole weight: 457.01. | |
| 2,3-Butanedione-2-monoxime | 2,3-Butanedione-2-monoxime (BDM) is a non-selective, reversible myosin ATPase inhibitor with phosphatase-like properties. It is non-selective myosin ATPase inhibitor (Ki = 5 mM at myosin II). Uses: Cholinesterase reactivators. Synonyms: BDM; Diacetyl Monoxime; NSC 660; NSC 116103; Biacetyl monooxime. Grades: ≥95%. CAS No. 57-71-6. Molecular formula: C4H7NO2. Mole weight: 101.1. | |
| 23-cGAM(PS)2 (Rp/Sp) | Cas No. 1637675-05-8. | |
| 2,3-Diaminonaphthalene | 2,3 Diaminonaphthalene is a highly selective colorimetric and fluorometric reagent for selenium detection and also an inhibitor of nitric oxide (NO) formation. Synonyms: naphthalene-2,3-diamine; 2,3-diaminonaphthalene; 2,3-naphthalenediamine. CAS No. 771-97-1. Molecular formula: C10H10N2. Mole weight: 158.2. | |
| 2-(3-Pyrazolyl)ethanamine Dihydrochloride | Betazole hydrochloride is a histamine H2 agonist used clinically to test gastric secretory function. Synonyms: 2-(1H-pyrazol-5-yl)ethanamine;dihydrochloride; 2-(1H-pyrazol-5-yl)ethanamine;dihydrochloride. Grades: ≥ 98 %. CAS No. 138-92-1. Molecular formula: C5H11Cl2N3. Mole weight: 184.07. | |
| 2,3-Pyridinedicarboxylic acid | Quinolinic acid is an endogenous NMDA agonist and transmitter candidate. It may distinguish between NMDA receptor subtypes. By overactivating NMDA receptors, quinolinic acid produces neurotoxicity, which has been implicated in certain neurodegenerative disorders. Uses: A metabolite of tryptophan; used to make assert (herbicide) and nicotinic acid. Synonyms: pyridine-2,3-dicarboxylic acid. Grades: 99 %. CAS No. 89-00-9. Molecular formula: C7H5NO4. Mole weight: 167.12. | |
| 24, 25-Dihydroxy VD2 | 24, 25-Dihydroxy VD2 is a hydroxylated metabolite of Vitamin D2, which is a synthetic analog of Vitamin D. Synonyms: 24, 25-Dihydroxy VD2; 58050-55-8; (E, 6R) -6- [ (1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5-hydroxy-2-methylidenecyclohexylidene] ethylidene] -7a-methyl-2, 3, 3a, 5, 6, 7-hexahydro-1H-inden-1-yl] -2, 3-dimethylhept-4-ene-2, 3-diol; 24,25-Dihydroxy Vitamin D2; CS-0802; DTXSID80735363; HY-76801; MS-27598; PD100785; 24,25-Dihydroxy Vitamin D2 (mixture of diastereomers); (3S,5Z,7E,22E,24xi)-9,10-Secoergosta-5,7,10,22-tetraene-3,24,25-triol. Grades: >98%. CAS No. 58050-55-8. Molecular formula: C28H44O3. Mole weight: 428.65. | |
| 2,4,6-Tribromophenyl caproate | 2,4,6-Tribromophenyl caproate is an anti-fungal agent. Synonyms: (2,4,6-tribromophenyl) hexanoate; Caproic acid 2,4,6-tribromophenyl ester; 2,4,6-tribromophenyl caproate; (2,4,6-tribromophenyl) hexanoate; AC1LBZXG. CAS No. 16732-09-5. Molecular formula: C12H13Br3O2. Mole weight: 428.94. | |
| 2,4-Diamino-6-hydroxypyrimidine | 2,4-Diamino-6-hydroxypyrimidine has been found to be a GCH1 inhibitor and could suppress the activity of NO synthase through preventing the synthesis of BH4. Uses: Enzyme inhibitors. Synonyms: 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diaminopyrimidin-4-one; 6-Aminoisocytosine; NSC 44914; NSC 680818; NSC 9302; 4(3H)-Pyrimidinone, 2,6-diamino-; 2,6-Diamino-4(3H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,6-diamino-; 2,4-Diamino-6-pyrimidinone; 2,6-Diamino-1,4-dihydropyrimidin-4-one; 2,6-Diamino-1H-pyrimidin-4-one; 2,6-Diamino-3,4-dihydropyrimidin-4-one; 2,6-Diamino-3H-pyrimidin-4-one; 2,6-Diamino-4-pyrimidinol; 4-Hydroxypyrimidine-2,6-diamine; 6-Hydroxy-2,4-diaminopyrimidine; 6-Hydroxy-2,4-pyrimidinediamine. Grades: ≥95%. CAS No. 56-06-4. Molecular formula: C4H6N4O. Mole weight: 126.12. | |
| 2,4-DMA hydrochloride | 2,4-DMA hydrochloride is an analytical reference standard that is classified as an amphetamine. It is a serotonin 5-HT2 receptor agonist with an apparent pA2 value of 5.6. Synonyms: 2,4-Dimethoxyamphetamine hydrochloride; 1-(2,4-dimethoxyphenyl)propan-2-amine hydrochloride. Grades: ≥98%. CAS No. 33189-36-5. Molecular formula: C11H17NO2·HCl. Mole weight: 231.7. | |
| 2,4-DPD | 2,4-DPD is a cell-permeable, competitive inhibitor of HIF-α prolyl hydroxylase (HIF-PH). Synonyms: 2,4-Diethylpyridine dicarboxylate; Diethyl pyridine-2,4-dicarboxylate; diethyl lutidinate. Grades: ≥98%. CAS No. 41438-38-4. Molecular formula: C11H13NO4. Mole weight: 223.2. | |
| 24-Hydroxycholesterol | 24-Hydroxycholesterol, also known as 24-OH-Chol, a natural sterol, is the main cholesterol elimination product of the brain. 24-Hydroxycholesterol is a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. 24-Hydroxycholesterol acts as a neurotoxin to SH-SY5Y human neuroblastoma cells which showed corresponding morphological changes: the cells became round, lost adhesion to the petri-dish, and neurite outgrowth degenerated. Synonyms: (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol; 24-hydroxycholesterol; 24S-hydroxycholesterol; cerebrosterol; cholest-5-ene-3,24-diol. CAS No. 30271-38-6. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| 2,4-Pyridinedicarboxylic acid monohydrate | 2,4-Pyridinedicarboxylic acid (2,4-PDCA) is a compound that structurally mimics 2-oxoglutarate (2-OG, also known as α-ketoglutarate) and chelates zinc, thus affecting a range of enzymes. Synonyms: pyridine-2,4-dicarboxylic acid;hydrate. Grades: ≥ 98 %. CAS No. 207671-42-9. Molecular formula: C7H5NO4 · H2O. Mole weight: 185.13. | |
| 2,4-Pyrimidinediamine with linker | 2,4-Pyrimidinediamine with linker is a patent compound in WO2013055780A1, Page 71; multikinase inhibitor and has a -NH2 terminal linker for further synthesis. Synonyms: 2,4-Pyrimidinediamine with linker; UNC0064-12, UNC-0064-12, UNC 0064-12, UNC006412, UNC-006412, UNC 006412. Grades: >98%. CAS No. 1430089-64-7. Molecular formula: C19H24N8. Mole weight: 364.45. | |
| 24(R)-hydroxycholesterol | 24(S)-Hydroxy cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis. 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRα and LXRβ nuclear receptors with slightly reduced potency. Synonyms: (24R)-cholest-5-ene-3beta,24-diol; (3beta,24R)-Cholest-5-ene-3,24-diol. Grades: ≥98%. CAS No. 27460-26-0. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| (24R)-MC 976 | Cas No. 112828-09-8. | |
| (24S)-24,25-Dihydroxyvitamin D3 | (24S)-24,25-Dihydroxycholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. Synonyms: (24S)-24,25-Dihydroxyvitamin D3; 55700-58-8; (24S)-Secalciferol; 24S,25-Dihydroxycholecalciferol; (24S)-24,25-dihydroxyvitamin D3 / (24S)-24,25-dihydroxycholecalciferol; (5Z,7E)-(3S,24S)-9,10-seco-5,7,10(19)-cholestatriene-3,24,25-triol; EVQ6RX7DAN; Secalciferol, (24S)-; 24S,25-Dihydroxyvitamin D3; (3S, 6R) -6- [ (1R, 3aS, 4E, 7aR) -4- [ (2Z) -2- [ (5S) -5-hydroxy-2-methylidenecyclohexylidene] ethylidene] -7a-methyl-2, 3, 3a, 5, 6, 7-hexahydro-1H-inden-1-yl] -2-methylheptane-2, 3-diol; 24(S),25-Dihydroxyvitamin D3; PRI-1202; LMST03020274; MFCD11114064; AKOS030526847; CS-0931; HY-15439; MS-27263; (24S)-24,25-Dihydroxyvitamin D3, >=95.0% (HPLC); 2,3-HEPTANEDIOL, 2-METHYL-6-((1R,3AS,4E,7AR)-OCTAHYDRO-4-((2Z)-2-((5S)-5-HYDROXY-2-METHYLENECYCLOHEXYLIDENE)ETHYLIDENE)-7A-METHYL-1H-INDEN-1-YL)-, (3S,6R)-. Grades: >98%. CAS No. 55700-58-8. Molecular formula: C27H44O3. Mole weight: 416.64. | |
| 24(S),25-Epoxy cholesterol | 24(S),25-Epoxy cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain. Synonyms: 24,25-epoxy-cholesterol; 24S,25-epoxy-cholesterol; 24S,25-epoxy-cholest-5-en-3beta-ol; 24S,25-EpoxyC. Grades: ≥95%. CAS No. 77058-74-3. Molecular formula: C27H44O2. Mole weight: 400.64. | |
| 25(S)-27-Hydroxy cholesterol | 25(S)-27-Hydroxy cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRα and LXRβ in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis. Synonyms: (25S)-26-hydroxy cholesterol; 26-OHC. Grades: ≥95%. CAS No. 56845-83-1. Molecular formula: C27H46O2. Mole weight: 402.7. | |
| 2,6-DMA hydrochloride | 2,6-DMA hydrochloride is an analytical reference standard that is classified as an amphetamine. It is a serotonin 5-HT2 receptor agonist with an apparent pA2 value of 5.09. Synonyms: 2,6-Dimethoxyamphetamine; 2,6-dimethoxy-alpha-methyl-benzeneethanamine monohydrochloride; 1-(2,6-dimethoxyphenyl)propan-2-amine hydrochloride. Grades: ≥98%. CAS No. 3904-11-8. Molecular formula: C11H17NO2·HCl. Mole weight: 231.7. | |
| 2-Acetamido-5-nitrothiazole | Nithiamide is efficient in preventing and treating swine dysentery in experimentally inoculated pigs. Synonyms: CL 5279; CL5279; CL-5279; Nithiamide; NSC 45914; NSC-45914; NSC45914. Grades: >98%. CAS No. 140-40-9. Molecular formula: C5H5N3O3S. Mole weight: 187.18. | |
| 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide | 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide is a sulfide-like inhibitor of phosphodiesterase 7 (PDE7; IC50 = 2.1 μM). It is selective for PDE7A, producing only 10-11% inhibition of PDE3A, PDE4D, and PDE4B at 10 μM. Synonyms: 2'-(5-chloro-2-nitrophenylthio)-acetanilide; 2'-(2-Nitro-5-chlorophenylthio)acetoanilide. Grades: ≥98%. CAS No. 107522-19-0. Molecular formula: C14H11ClN2O3S. Mole weight: 322.8. | |
| 2-Acetylphenothiazine | ML 171is a NADPH oxidase 1 (NOX1) inhibitor. It can block NOX1-dependent ROS generation. Synonyms: 1-(10H-phenothiazin-2-yl)ethanone. Grades: ≥ 98 % by HPLC. CAS No. 6631-94-3. Molecular formula: C14H11NOS. Mole weight: 241.31. | |
| 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine | 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a food-derived carcinogen that is found in high temperature-cooked fish and meat. In humans, PhIP is metabolized by the cytochrome (CYP) P450 isoform CYP1A2 and conjugated by N-acetyltransferase or sulfotransferase to a metabolite that reacts with DNA to form adducts, which are directly correlated with increased risk of breast, colon, and prostate cancers. Synonyms: PhIP; 1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-amine. Grades: ≥98%. CAS No. 105650-23-5. Molecular formula: C13H12N4. Mole weight: 224.3. | |
| 2-Aminobenzenesulfonamide | 2-Aminobenzenesulfonamide is a potent inhibitor of carbonic anhydrase B. Synonyms: 2-aminobenzenesulfonamide. Grades: 98 %. CAS No. 3306-62-5. Molecular formula: C6H8N2O2S. Mole weight: 172.20. | |
| 2-APB | 2-APB, a transient receptor potential (TRP) activator for TRPV1, TRPV2, and TRPV3, could probably be used against diseases caused by hypersensitivity and temperature misregulation. Synonyms: 2-Aminoethoxydiphenylborane. Grades: ≥98% by HPLC. CAS No. 524-95-8. Molecular formula: C14H16BNO. Mole weight: 225.10. | |
| 2-Arachidonoylglycerol | 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Synonyms: 2-AG; 2-Arachidonoyl Glycerol; glyceryl 2-arachidonate; 2-Ara-Gl; MG(0:0/20:4(5Z,8Z,11Z,14Z)/0:0); 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol. Grades: >99%. CAS No. 53847-30-6. Molecular formula: C23H38O4. Mole weight: 378.55. | |
| 2B-(SP) | 2B-(SP) is a selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3). Synonyms: 186901-17-7; 2B-(SP)L-Leucine,L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-a-glutamyl-L-a-glutamyl-L-leucyl-L-a-aspartyl-L-seryl-L-arginyl-L-alanylglycyl-O-phosphono-L-seryl-L-prolyl-L-glutaminyl-AKOS024456793L-Leucine,L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-a-glutamyl-L-a-glutamyl-L-leucyl-L-a-aspartyl-L-seryl-L-arginyl-L-alanylglycyl-O-phosphono-L-seryl-L-prolyl-L-glutaminyl-(9CI). CAS No. 186901-17-7. Molecular formula: C71H123N26O29P. Mole weight: 1835.88. | |
| 2-(Carboxymethoxy)-5-[(2S)-2-[[(2S)-2-(3-carboxypropanoylamino)-3-phenylpropanoyl]amino]-3-oxo-3-(pentylamino)propyl]benzoic acid | 2-(Carboxymethoxy)-5-[(2S)-2-[[(2S)-2-(3-carboxypropanoylamino)-3-phenylpropanoyl]amino]-3-oxo-3-(pentylamino)propyl]benzoic acid is an esteemed biomedical compound used for studying bacterial infections. Moreover, it has remarkable antitumor attributes. Molecular formula: C30H37N3O10. Mole weight: 599.6. | |
| 2-Chloro-5-nitrobenzanilide | GW9662 is a potent, irreversible and selective PPARgamma antagonist, which prevented activation of PPARgamma and inhibited growth of human mammary tumour cell lines. GW9662 may permit use of anti-ER strategies to inhibit breast cancer in ER- patients. Synonyms: 2-chloro-5-nitro-N-phenylbenzamide. Grades: 98 %. CAS No. 22978-25-2. Molecular formula: C13H9ClN2O3. Mole weight: 276.68. | |
| 2-CMDO | 2-CMDO has been found to be a dopamine D4 receptor antagonist and could also exhibit neuroleptic and extrapyramidal effects. Synonyms: 2-CMDO; 2 CMDO; 2-Chloro-11-(4-methylpiperazino)dibenz(Z)[b, f]oxepin maleate. Grades: ≥98% by HPLC. CAS No. 24140-98-5. Molecular formula: C19H19ClN2O.C4H4O4. Mole weight: 442.90. | |
| 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine | 2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine is a nonpeptidic angiotensin II receptor antagonist whose imidazo[4,5-b]pyridine scaffold has been used to examine a variety of positional substitutions in the development of orally active, long duration antihypertensive agents. Synonyms: 3H-Imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl-. Grades: ≥98%. CAS No. 133240-06-9. Molecular formula: C10H13N3. Mole weight: 175.2. | |
| 2-Furoyl-LIGRLO amide trifluoroacetate salt | 2-Furoyl-LIGRLO amide is a potent and selective agonist of the proteinase-activated receptor, PAR2 (pD2 = 7.0). Grades: ≥95%. Molecular formula: C36H63N11O8·xCF3COOH. Mole weight: 777.9. | |
| 2-Hexyl-4-pentynoic acid | 2-hexyl-4-pentynoic acid is a derivative of valproic acid, an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC50 = 13 μM) than valproic acid (IC50 = 398 μM). Synonyms: 2-(prop-2-yn-1-yl)octanoic acid. Grades: ≥95%. CAS No. 96017-59-3. Molecular formula: C11H18O2. Mole weight: 182.3. | |
| 2-Hydroxysaclofen | 2-Hydroxysaclofen is a GABAB receptor antagonist. Uses: Gaba-b receptor antagonists. Synonyms: (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic Acid; β-(Aminomethyl)-4-chloro-β-hydroxybenzeneethanesulfonic Acid. CAS No. 117354-64-0. Molecular formula: C9H12ClNO4S. Mole weight: 265.71. | |
| 2-Imino-4-methylpiperidine acetate | 2-Imino-4-methylpiperidine is a potent, general NOS inhibitor. Synonyms: 4-Methyl-3,4,5,6-tetrahydropyridin-2-amine acetate. Grades: ≥98%. CAS No. 165383-72-2. Molecular formula: C6H12N2·C2H3O2. Mole weight: 171.2. | |
| 2-Iminopiperidine hydrochloride | 2-Iminopiperidine hydrochloride is the hydrochloride salt of 2-Iminopiperidine, which is a potent inhibitor of human nitric oxide synthase isoform (iNOS). It is selective for iNOS and is more potent than NG-methyl-L-arginine. Synonyms: 2-Pyridinamine, 3,4,5,6-tetrahydro-, hydrochloride (1:1); 2-Pyridinamine, 3,4,5,6-tetrahydro-, monohydrochloride; Piperidine, 2-imino-, monohydrochloride; (3,4,5,6-Tetrahydropyridin-2-yl)amine monohydrochloride; 3,4,5,6-Tetrahydro-2-pyridinamine Hydrochloride. Grades: ≥95%. CAS No. 16011-96-4. Molecular formula: C5H11N2Cl. Mole weight: 134.61. | |
| 2-Iodomelatonin | 2-Iodomelatonin is a potent agonist of the melatonin receptors 1 (MT1) with Ki value of 28 pM. It could be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues. It inhibits forskolin-stimulated cAMP production in CHO cells expressing human MT1 30-fold more potently than melatonin. It has been used to characterize the role of MT1 in melatonin-mediated signaling. It is useful in receptor binding studies with radioactive iodomelatonin. Synonyms: N-[2-(2-Iodo-5-methoxyindol-3-yl)ethyl]acetamide; N-Acetyl-2-iodo-5-methoxytryptamine. Grades: ≥98% by HPLC. CAS No. 93515-00-5. Molecular formula: C13H15IN2O2. Mole weight: 358.18. | |
| 2-methoxyestradiol | 2-methoxyestradiol, also known as 2-ME, is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis. Uses: Antineoplastic agents. Synonyms: 2-ME; 2-Methoxy Estradiol. US brand name: Panzem. Abbreviation: 2ME2. Chemical structure name: (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol. Grades: 0.98. CAS No. 362-07-2. Molecular formula: C19H26O3. Mole weight: 302.414. | |
| 2-Methyl-5-hydroxytryptamine hydrochloride | 2-Methyl-5-hydroxytryptamine hydrochloride is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM). It affects the gut functions including secretion, muscle contraction and enteric nervous activity. Synonyms: 2-Me-5-HT Hydrochloride; 2-Methyl-5-HT Hydrochloride; 2-Methyl-5-hydroxytryptamine Hydrochloride; 2-Methylserotonin Hydrochloride. Grades: ≥98% by HPLC. CAS No. 845861-49-6. Molecular formula: C11H14N2O.HCl. Mole weight: 226.71. | |
| (±)-2-Methyl Arachidonoyl-2'-Fluoroethylamide | (±)-2-Methyl arachidonoyl-2'-fluoroethylamide (2-Methyl-2'-fluoro AEA) is an analog of anandamide (AEA) in which the alcohol of the ethanolamide group has been removed and replaced with a fluorine atom. An analog of arachidonylethanolamide that is a strong, selective CB1 cannabinoid receptor agonist. Synonyms: 2-methyl-2'-fluoro AEA; 2-Methyl-2'-fluoro Anandamide; O-689; (A+/-)-2-Methylarachidonoyl-2'-fluoroethylamide N-(2-fluoroethyl)-2-methylicosa-5,8,11,14-tetraenamide. Grades: ≥95%. CAS No. 166100-39-6. Molecular formula: C23H38FNO. Mole weight: 363.6. | |
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