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LXW7
LXW7 is a αvβ3 integrin ligand. Synonyms: LXW7; 1313004-77-1; SCHEMBL15082201; H-D-Cys(1)-Gly-Arg-Gly-Asp-D-Asp-D-Val-D-Cys(1)-NH2; HY-P0178; CS-0021086. Grade: >98%. CAS No. 1313004-77-1. Molecular formula: C29H48N12O12S2. Mole weight: 820.89.
Lycocitin-1
Lycocitin-1 has antibacterial and antifungal activities. Lycocitin 1 was found in venom glands, the wolf spider, Lycosa singoriensis. It is active against Gram-positive bacteria S. aureus, B. subtilis, Gram-negative E. coli, P. aeruginosa, and fungi (C. albicans) with MICs in the range of 0.4-50 μM. Grade: >97% by HPLC.
Lycocitin-2
Lycocitin-2 has antibacterial and antifungal activity. The source of Lycocitin-2 is venom glands, the wolf spider, Lycosa singoriensis. Grade: >97% by HPLC.
Lycocitin-3
Lycocitin-3 has antibacterial and antifungal activity. The source of Lycocitin-3 is venom glands, the wolf spider, Lycosa singoriensis.
Lycosin-I
Lycosin-I is a 24-residue cationic anticancer peptide derived from Lycosa singorensis with high structural similarity to several cationic and amphiphilic antimicrobial peptides. Lycosin-I showed rapid, selective and broad-spectrum bactericidal activity and a synergistic effect with traditional antibiotics.
Lycotoxin-1
Two peptide toxins with antimicrobial activity, lycotoxins I and II, were identified from venom of the wolf spiderLycosa carolinensis (Araneae: Lycosidae) by virtue of their abilities to reduce ion and voltage gradients across membranes.
Lycotoxin-2
Two peptide toxins with antimicrobial activity, lycotoxins I and II, were identified from venom of the wolf spiderLycosa carolinensis (Araneae: Lycosidae) by virtue of their abilities to reduce ion and voltage gradients across membranes.
LyeTxI-bPEG
LyeTxI-bPEG is effective against carbapenem-resistant Acinetobacter baumannii in an in vivo model of pneumonia and shows reduced toxicity. Synonyms: Pegylated LyeTx I-b peptide.
lymphocyte antigen 6 complex locus K (114-133)
Lymphocyte antigen 6 complex locus K (114-133) is a peptide corresponding to residues 114-133 of lymphocyte antigen 6 complex locus K. LY6K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas. Synonyms: Cancer/Testis Antigen 97 (114-133); Lymphocyte Antigen 6K (114-133).
lymphocyte antigen 6 complex locus K (119-128)
Lymphocyte antigen 6 complex locus K (119-128) is a peptide corresponding to residues 119-128 of lymphocyte antigen 6 complex locus K. LY6K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas. Synonyms: Cancer/Testis Antigen 97 (119-128); Lymphocyte Antigen 6K (119-128).
lymphocyte antigen 6 complex locus K (61-84)
Lymphocyte antigen 6 complex locus K (61-84) is a peptide corresponding to residues 61-84 of lymphocyte antigen 6 complex locus K. LY6K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas. Synonyms: Cancer/Testis Antigen 97 (61-84); Lymphocyte Antigen 6K (61-84).
Lymphocytes T, human
T lymphocytes, also known as T cells, are a type of white blood cell that help protect the body from infection and cancer. Synonyms: Ala-Ala-Ala-Ile-Ser-Cys-Val-Gly-Ser-Pro-Glu-Cys-Pro-Pro-Lys-Cys-Arg-Ala-Gln-Gly-Cys-Lys-Asn-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-Lys-Cys-Lys-Lys-Cys-NH2 (Disulfide bond Cys6/Cy26, Cys12/Cys31, Cys16/Cys33, Cys21/Cys36). Molecular formula: C151H259N53O43S9. Mole weight: 3793.80.
Lymphocytic Choreomeningitis Virus (LCMV) Glycoprotein 33 (33-41) is the H-2Db restricted epitope derived from the lymphocytic choreomeningitis virus (LCMV) glycoprotein gp 33. Synonyms: LCMV GP1, gp 33 (33-41); H-Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys-OH; L-lysyl-L-alanyl-L-valyl-L-tyrosyl-L-asparagyl-L-phenylalanyl-L-alanyl-L-threonyl-L-cysteine. Molecular formula: C46H69N11O13S. Mole weight: 1016.2.
LyP-1, Peptide 1
LyP-1 is a cyclic cryptic CendR peptide and selectively binds to p32 receptors overexpressed in various tumor-associated cells. CAS No. 454487-07-1. Molecular formula: C36H65N17O12S2. Mole weight: 992.14.
Lys12(γ-Glu-palmitoyl), Exendin-4
Lys12(γ-Glu-palmitoyl), Exendin-4 is a modified version of exendin-4, a peptide hormone that may help treat type 2 diabetes and obesity. It's a glucagon-like peptide-1 (GLP-1) receptor agonist that can help reduce blood glucose levels. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys(γ-Glu-palmitoyl)-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Mole weight: 4554.07.
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys(N3)-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C189H293N52O61S. Mole weight: 4311.96.
Lys27(γ-Glu-palmitoyl), Exendin-4
Lys27(γ-Glu-palmitoyl) is a modification of the peptide Exendin-4, which is used to treat diabetes and obesity. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys(γ-Glu-palmitoyl)-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Mole weight: 4554.07.
Specific substrate for dipeptidyl aminopeptidase. Synonyms: Lys-Ala-β-naphthylamide; l-lysyl-alanine-2-naphthylamide; Lys Ala βNA. Grade: 95%. CAS No. 20314-31-2. Molecular formula: C19H26N4O2. Mole weight: 342.44.
Lys(Boc)5, Octreotide impurity
Lys(Boc)5, Octreotide impurity is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: (D-Phe)-Cys-Phe-(D-Trp)-Lys(Boc)-Thr-Cys-Thr-Ol (Disulfide bond Cys2/Cys7); D-Phe-Cys-Phe-D-Trp-Lys(Boc)-Thr-Cys-Thr-Ol (Disulfide bond Cys2/Cys7). Molecular formula: C54H75N10O13S2. Mole weight: 1136.42.
Lys-Gly-Tyr
Lys-Gly-Tyr is a tripeptide composed of L-lysine, glycine, and L-tyrosine. L-lysine is essential for protein synthesis and tissue repair, glycine supports various metabolic functions and central nervous system health, while L-tyrosine is involved in neurotransmitter synthesis and cognitive function. This peptide may contribute to improved neurotransmitter balance, muscle repair, and overall metabolic support, potentially offering benefits in both cognitive and physical health contexts. Synonyms: KGY; L-Lysylglycyl-L-tyrosine; L-Tyrosine, N-(N-L-lysylglycyl)-; Lysyl-glycyl-tyrosine; L-Lysyl-glycyl-L-tyrosine; H-Lys-Gly-Tyr-OH; H-KGY-OH. Grade: ≥90%. CAS No. 106326-66-3. Molecular formula: C17H26N4O5. Mole weight: 366.41.
Lysinoalanine 2HCl
Lysinoalanine 2HCl. Uses: This not naturally occurring amino acid was first observed after alkali treatment of different proteins. synthetic lysinoalanine was found to have a strong chelating ability for metals. Synonyms: H-Lys(DL-2-amino-2-carboxyethyl)-OH 2HCl; Lysinoalanine Dihydrochloride. Grade: ≥ 99% (TLC). CAS No. 4418-81-9. Molecular formula: C9H19N3O4·2HCl. Mole weight: 306.19.
Lys-Lys-Lys
Lys-Lys-Lys is a cationic moiety that may be used in the construction of gene delivery vectors and DNA nanoparticles. Synonyms: Lysyllysyllysine; l-lysyl-l-lysyl-l-lysine; Trilysine; L-Lysine, L-lysyl-L-lysyl-; (S)-6-Amino-2-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanamido)hexanoic acid. Grade: ≥97%. CAS No. 13184-14-0. Molecular formula: C18H38 N6 O4. Mole weight: 402.53.
Lys-Lys-Lys-OH AcOH is a cationic moiety that may be used in the construction of gene delivery vectors and DNA nanoparticles. Synonyms: H-Lys-Lys-Lys-OH acetate salt; L-lysyl-L-lysyl-L-lysine acetate salt. Grade: ≥ 97%. Molecular formula: C18H38N6O4·C2H4O2. Mole weight: 462.59.
Lysozyme C
Lysozyme C is capable of both hydrolysis and transglycosylation and it also shows a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides. Uses: Lysozyme c, also known simply as lysozyme, is a potent enzyme commonly found in various bodily fluids such as tears, saliva, mucus, and human milk. it plays a vital role in the immune system as a natural antimicrobial agent, protecting the body from harmful bacteria by breaking down cell walls. in addition to its natural presence in the body, lysozyme c has been extensively studied and used in a v. Synonyms: 1,4-beta-N-acetylmuramidase C.
Lysozyme C, spleen isozyme
Lysozyme C, spleen isozyme is found in Equus caballus (Horse). Lysozyme C is capable of both hydrolysis and transglycosylation and it also shows a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides. Synonyms: 1,4-beta-N-acetylmuramidase C.
Lysozyme-like peptide
Lysozyme-like peptide is isolated from Tityus stigmurus (Brazilian scorpion). Lysozymes have primarily bacteriolytic function.
LZ1 peptide is a synthetically derived antimicrobial peptide. It is known for its potent bactericidal effects, broad-spectrum antimicrobial activity, and lack of hemolytic activity and toxicity towards eukaryotic cells. It also exhibits anti-inflammatory properties by inhibiting the secretion of inflammatory factors such as tumor necrosis factor-alpha (TNF-α) and interleukin (IL)-1β, which can help in managing inflammation caused by acne. LZ1 peptide is a potent antimicrobial agent used in cosmetics for its ability to combat acne-causing bacteria and reduce inflammation. It is known for its effectiveness in treating inflammatory acne, improving skin texture, and potentially reducing the appearance of acne scars. Additionally, LZ1 peptide contributes to skin health by providing antioxidant properties and combating free radicals, which can help prevent skin aging and soothe sun-induced damage. Synonyms: LZ1 antimicrobial peptide; Antimicrobial peptide LZ1 peptide; LZ1; H-Val-Lys-Arg-Trp-Lys-Lys-Trp-Trp-Arg-Lys-Trp-Lys-Lys-Trp-Val-NH2; H-VKRWKKWWRKWKKWV-NH2; L-Valyl-L-lysyl-L-arginyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-L-tryptophyl-L-arginyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysyl-L-tryptophyl-L-valinamide; Val-Lys-Arg-Trp-Lys-Lys-Trp-Trp-Arg-Lys-Trp-Lys-Lys-Trp-Val-NH2. Grade: ≥95%. CAS No. 1423743-97-8. Molecular formula: C113H167N33O15. Mole weight: 2227.75.
M-2420
M-2420 is a fluorescent substrate for β-secretase sites containing Swedish mutations in amyloid precursor protein (APP). Synonyms: Methoxycoumarin-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys-dinitrophenyl. Grade: ≥95%. CAS No. 310427-95-3. Molecular formula: C70H91N15O27. Mole weight: 1574.56.
M65
M65 is a potent and specific antagonist of PAC1 receptor. Synonyms: PAC1 Receptor Antagonist M65; H-Cys-Asp-Ala-Thr-Cys-Gln-Phe-Arg-Lys-Ala-Ile-Asp-Asp-Cys-Gln-Lys-Gln-Ala-His-His-Ser-Asn-Val-Pro-Gly-Asn-Ser-Val-Phe-Lys-Glu-Cys-Met-Lys-Gln-Lys-Lys-Lys-Glu-Phe-Lys-Ala-NH2 (Disulfide bridge: Cys1-Cys5, Cys14-Cys32). Grade: ≥95%. CAS No. 1872440-65-7. Molecular formula: C205H326N64O61S5. Mole weight: 4823.57.
Macropin 1
Macropin-1 (MAC-1) is an anti-microbial peptide (AMP) isolated from venom of the solitary bee Macropis fulvipes (Hymenoptera: Melittidae). MAC-1 has activity against both Gram-positive and Gram-negative bacteria, including drμg-resistant strains. MAC-1 can inhibit biofilm formation in Staphylococcus aureus and Pseudomonas aeruginosa and also exhibits anti-fungal activity. MAC-1 has little to no haemolytic activity against human cells at microbiologically effective concentrations. Synonyms: MAC-1. Grade: >95% by HPLC. Molecular formula: C68H120N16O13S. Mole weight: 1401.84.
Macropin 2
Macropin 2 has antimicrobial activity. The source of Macropin 2 is venom, the solitary bee Macropis fulvipes. Synonyms: MAC-2. Grade: >95% by HPLC. Molecular formula: C83H151N27O21S4. Mole weight: 1991.51.
Maculatin 1.1
Maculatin 1.1 is an antimicrobial peptide from the Australian tree frog. Maculatin-1.1 shows significant antibacterial activity against Gram-positive bacteria, less against Gram-negative bacteria. Molecular formula: C103H161N27O23. Mole weight: 2145.54.
Maculatin-1.1
Maculatin-1.1.
Maculatin 1.1.1
Maculatin 1.1.1, which arises from the action of an endogenous endoprotease to remove the first two residues of maculatin 1.1, is essentially inactive.
Maculatin 1.2
Maculatin 1.2, which has two more residues at its C-terminus than maculatin 1.1, has markedly reduced activity compared with maculatin 1.1.
Maculatin 1.3
The peptide is HIV inhibitory (EC50=4 μM). The source of Maculatin 1.3 is Litoria eucnemis, Australia area. Grade: >96% by HPLC. Molecular formula: C98H160N26O23. Mole weight: 2070.47.
Maculatin 1.4
Maculatin 1.4 has antimicrobial activity. Maculatin 1.4 was found in Litoria eucnemis, Australia. Grade: >98% by HPLC. Molecular formula: C98H167N27O25. Mole weight: 2123.53.
Maculatin 2.1
Maculatin 2.1 was found in Litoria genimaculate, Litoria eucnemis, Australia. Maculatin 2.1 shows antibacterial activity against B.cereus, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis. Grade: >95% by HPLC. Molecular formula: C88H143N21O24. Mole weight: 1879.20.
Maculatin 3.1
Maculatin 3.1 was found in Litoria genimaculate, Australia. Maculatin 3.1 shows antibacterial activity against S.uberis. Grade: >95% by HPLC. Molecular formula: C121H214N32O38. Mole weight: 2725.18.
Magainin 1 acetate is a peptide antibiotic with antibacterial and antiparasitic activities, originally extracted from the skin of Xenopus laevis. It has a broad spectrum of non-specific activity against a variety of microorganisms, including viruses, gram-positive and gram-negative bacteria, protozoa, yeast and fungi, and may also have hemolytic and cytotoxicity to cancer cells. Magainin 1 is a fungicide. Magainin 1 has an inhibitory effect on herpes simplex virus type 1 (HSV-1) and HSV-2. Synonyms: Magainin I acetate; Magainin 1 (Xenopus laevis laevis) acetate; Magainin 1 (Xenopus laevis sudanensis) acetate; Magainin 1 (Xenopus laevis victorianus) acetate; Magainin 1 (Xenopus petersII) acetate; Magainin-I peptide acetate; H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Gly-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Lys-Ser-OH.CH3CO2H; glycyl-L-isoleucyl-glycyl-L-lysyl-L-phenylalanyl-L-leucyl-L-histidyl-L-seryl-L-alanyl-glycyl-L-lysyl-L-phenylalanyl-glycyl-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-glycyl-L-alpha-glutamyl-L-isoleucyl-L-methionyl-L-lysyl-L-serine acetate. Grade: ≥95%. Molecular formula: C114H181N29O30S. Mole weight: 2469.90.
Magainin-AM2
Magainin-AM2, an amphibian host-defense peptide, stimulates insulin- and glucagon-like peptide-1-release in vitro.
Magainin-St1
Magainin-St1 is isolated from the African clawed frog Silurana tropicalis and has anti Gram-positive and Gram-negative activities.
MAGE-10 (254-262)
MAGE-10 (254-262) is a peptide derived from MAGE-10. MAGE-10 is a highly immunogenic member of the MAGE-A family of cancer/testis tumor-associated antigens (C/T TAAs). MAGE-10 is frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies. Synonyms: Cancer/testis antigen 1.10 (254-262); MAGE-10 antigen (254-262); Melanoma-associated antigen 10 (254-262).
MAGE-10 (290-298)
MAGE-10 (290-298) is a peptide derived from MAGE-10. MAGE-10 is a highly immunogenic member of the MAGE-A family of cancer/testis tumor-associated antigens (C/T TAAs). MAGE-10 is frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies. Synonyms: Cancer/testis antigen 1.10 (290-298); MAGE-10 antigen (290-298); Melanoma-associated antigen 10 (290-298).
MAGE-1 (102-112)
MAGE-1 (102-112) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (102-112); MAGEA1 (102-112).
MAGE-12 (114-127)
MAGE-12 (114-127) is a bioactive peptide of MAGE-12 which is frequently expressed in malignant melanoma. Synonyms: Melanoma-associated antigen 12 (114-127); Cancer/testis antigen 1.12 (114-127).
MAGE-12 (127-141)
MAGE-12 (127-141) is a bioactive peptide of MAGE-12 which is frequently expressed in malignant melanoma. Synonyms: Melanoma-associated antigen 12 (127-141); Cancer/testis antigen 1.12 (127-141).
MAGE-12 (170-178)
MAGE-12 (170-178) is a bioactive peptide of MAGE-12 which is frequently expressed in malignant melanoma. Synonyms: Melanoma-associated antigen 12 (170-178); Cancer/testis antigen 1.12 (170-178).
MAGE-1 (222-231)
MAGE-1 (222-231) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (222-231); MAGEA1 (222-231).
MAGE-1 (230-238)
MAGE-1 (230-238) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (230-238); MAGEA1 (230-238).
MAGE-1 (268-282)
MAGE-1 (268-282) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (268-282); MAGEA1 (268-282).
MAGE-1 (278-286)
MAGE-1 (278-286) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (278-286); MAGEA1 (278-286).
MAGE-1 (281-292)
MAGE-1 (281-292) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (281-292); MAGEA1 (281-292).
MAGE-1 (289-298)
MAGE-1 (289-298) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (289-298); MAGEA1 (289-298).
MAGE-1 (62-70)
MAGE-1 (62-70) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (62-70); MAGEA1 (62-70).
MAGE-1 (90-104)
MAGE-1 (90-104) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (90-104); MAGEA1 (90-104).
MAGE-1 (96-104)
MAGE-1 (96-104) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Melanoma-associated antigen 1 (96-104); MAGEA1 (96-104).
MAGE-1 Antigen (161-169) (human)
MAGE-1 Antigen (161-169) (human) is a truncated fragment of MAGE-1 which is a gene that encodes an antigen on a melanoma cell line. MAGE-1 is expressed by melanoma tissue from all stages of disease, but not melanocytes, nevus tissue, or any normal diploid cell line tested. Synonyms: Glu-Ala-Asp-Pro-Thr-Gly-His-Ser-Tyr; H2N-EADPTGHSY-OH; Melanoma-associated antigen 1 (161-169). CAS No. 144449-86-5. Molecular formula: C41H57N11O17. Mole weight: 975.95.
MAGE-2 (127-136)
MAGE-2 is an antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. It reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Synonyms: Melanoma-associated antigen 2 (127-136); MAGEA2 (127-136); Cancer/testis antigen 1.2 (127-136).
MAGE-2 (156-164)
MAGE-2 is an antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. It reduces p53/TP53 transactivation function through recruitment of HDAC3 to p53/TP53 transcription sites. Synonyms: Melanoma-associated antigen 2 (156-164); MAGEA2 (156-164); Cancer/testis antigen 1.2 (156-164).