BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| BSc2118 | BSc2118 is a potent proteasome inhibitor. BSc2118 shows significant antimyeloma activity and may be considered as a promising agent in cancer drug development. BSc2118 is also a promising new candidate for stroke therapy, which may in addition alleviate recombinant tissue-plasminogen activator-induced brain toxicity. Synonyms: BSc-2118; BSc 2118. Grades: 98%. CAS No. 863924-64-5. Molecular formula: C28H43N3O7. Mole weight: 533.66. |  |
| b-Sitosterol b-D-glucuronide methyl ester | b-Sitosterol b-D-glucuronide methyl ester is a notable biomedical compound with potent anticancer attributes. Also, it exhibits insulin sensitivity in the realm of diabetes research. Molecular formula: C36H60O7. Mole weight: 604.86. | |
| BTB 02472 | BTB 02472 is an active-site-targeting COX-2 inhibitor. Synonyms: COX-2 Inhibitor III; N-(5-Acetyl-2-piperidinophenyl)-N' -(2,5-dichlorophenyl)thiourea. CAS No. 1177728-24-3. Molecular formula: C20H23Cl2N3OS. Mole weight: 424.39. | |
| BTB06584 | BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. It may represent a valuable tool to selectively inhibit mitochondrial F1 Fo-ATPase activity without compromising ATP synthesis and to limit ischaemia-induced injury caused by reversal of the mitochondrial F1 Fo-ATPsynthase. Synonyms: BTB06584; BTB-06584; BTB 06584. Grades: >98%. CAS No. 219793-45-0. Molecular formula: C19H12ClNO6S. Mole weight: 417.82. | |
| BTB-1 | BTB-1 is a novel small molecule inhibitor of the mitotic motor protein Kif18A, which was identified by Catarinella et al. during a highthroughput screen against Kif18A's MT-stimulated ATPase activity, with an IC50 of 1.7-1.9 M. It is selective within the kinesin subgroup of Kif4, Eg5, MKLP-1, MKLP-2, MPP1, CENP-E and MCAK, and during in vitro motility assays Kif18A's MT gliding ability was blocked by the addition of BTB-1 in a reversible manner. BTB-1 was found to be ATP competitive and MT uncompetitive, only inhibiting the ATPase activity of the MT-bound motor protein. BTB-1 could serve as a valuable tool in disentangling the nature of Kif18A's double functionality within mitosis and assessing for potential therapeutic utilities. Synonyms: BTB 1; BTB1; 4-Chloro-2-nitro-1-(phenylsulfonyl)benzene; 4-Chloro-2-nitrodiphenyl sulfone; NSC 156750. CAS No. 86030-08-2. Molecular formula: C12H8ClNO4S. Mole weight: 297.71. | |
| BTYNB | BTYNB is a potent and selective inhibitor of the binding of IMP1 to c-Myc mRNA (IC50=5 μM). BTYNB is selective and effective for IMP1-positive cancer cell lines. Synonyms: 2-{[(E)-(5-Bromothiophen-2-Yl)Methylidene]Amino}Benzamide. Grades: 98%. CAS No. 304456-62-0. Molecular formula: C12H9BrN2OS. Mole weight: 309.18. | |
| BTZ043 Racemate | BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. Synonyms: BTZ 043 Racemate; BTZ-043 Racemate; 2-(2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one. Grades: >98%. CAS No. 957217-65-1. Molecular formula: C17H16F3N3O5S. Mole weight: 431.39. | |
| Burapitant | Burapitant is a drug developed by Sanofi-Aventis which was one of the first compounds developed that acts as a potent and selective antagonist for the NK1 receptor. Synonyms: SSR240600; SSR-240600; SSR 240600; 1-[2-[(2R)-4-[2-[3,5-Bis(trifluoromethyl)phenyl]acetyl]-2-(3,4-dichlorophenyl)-2-morpholinyl]ethyl]-alpha,alpha-dimethyl-4-piperidineacetamide. Grades: >98%. CAS No. 537034-22-3. Molecular formula: C32H47N7O4. Mole weight: 682.53. | |
| Buserelin-NHNH2 trifluoroacetate salt | Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels by about 95% in both sexes, decreases the level of circulating gonadotropins and sex hormones. Buserelin can reduce tumor growth in a DMBA-induced rat model of mammary cancer. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being nafarelin. Buserelin is available as a generic medication. Grades: ≥95%. Molecular formula: C58H83N17O13·xCF3COOH. Mole weight: 1226.39. | |
| Butyl 2-acetamido-2-deoxy-b-D-glucopyranoside | Butyl 2-acetamido-2-deoxy-b-D-glucopyranoside, a prominent compound in the biomedical industry, serves diverse purposes. Its invaluable role lies in the synthesis of potential drug candidates, specifically catering to ailments like cancer and infectious diseases. This compound's distinctive characteristics render it indispensable for the advancement of targeted therapeutics and drug delivery systems, thereby revolutionizing the realm of biomedical research and development. CAS No. 94536-61-5. Molecular formula: C12H23NO6. Mole weight: 277.31. | |
| Butyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside | Butyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside, a highly esteemed biomedicine renowned for its remarkable pharmaceutical attributes, serves as an invaluable asset in addressing an extensive array of afflictions. Widely acknowledged for its unmatched efficacy in countering antibiotic-resistant bacterial infections and ameliorating the impact of neurodegenerative disorders, this compound stands as a prominent component within anti-infective medications. Synonyms: (5-acetamido-3,4-diacetyloxy-6-butoxyoxan-2-yl)methyl acetate; BUTYL 2-ACETAMIDO-3,4,6-TRI-O-ACETYL-BETA-D-GLUCOPYRANOSIDE. CAS No. 155197-37-8. Molecular formula: C18H29NO9. Mole weight: 403.42. | |
| Butyl a-D-glucopyranoside | Butyl α-D-glucopyranoside stands out as a versatile carbohydrate derivative extensively employed in the field of biomedicine. Functioning as a non-ionic surfactant, it holds significant importance for its role in enhancing solubility and stability in drug formulations. The diverse range of applications of this product includes drug delivery systems, biotechnological explorations, and pharmaceutical analysis. Its efficacy in enhancing the therapeutic potential of drugs renders it invaluable in the treatment of numerous ailments, encompassing cancer, diabetes, and neurodegenerative disorders. CAS No. 25320-93-8. Molecular formula: C10H20O6. Mole weight: 236.26. | |
| C-1 | C-1 is a protein kinase inhibitor selecitive for PKG, PKA and PKC (IC50 = 4, 8 and 12 μM, respectively) and is widely used as a ROCK inhibitor. Synonyms: HA 100; HA100; HA-100; 5-Piperazin-1-ylsulfonylisoquinoline; 1-(5-Isoquinolinesulfonyl)piperazine. Grades: ≥99% by HPLC. CAS No. 84468-24-6. Molecular formula: C13H15N3O2S. Mole weight: 277.34. | |
| C-(1-Bromo-1-deoxy-2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosyl)formamide | C-(1-Bromo-1-deoxy-2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosyl)formamide is a vital component in the development of novel antiviral drugs. Through its unique chemical structure, it exhibits potent antiviral activity against a range of infectious diseases, including influenza and herpes viruses. Synonyms: C-(2,3,4,6-Tetra-O-benzoyl-1-bromo-1-deoxy-b-D-glucopyranosyl)formamide. CAS No. 262849-68-3. Molecular formula: C35H28BrNO10. Mole weight: 702.5. | |
| C-(2,3,4,6-Tetra-O-acetyl-1-azido-1-deoxy-a-D-galactopyranosyl)formamide | C-(2,3,4,6-Tetra-O-acetyl-1-azido-1-deoxy-a-D-galactopyranosyl)formamide is a valuable compound utilized in the biomedical industry for its potential in treating infectious diseases caused by specific bacteria or viruses. Its structure and chemical properties make it an effective candidate for the development of antiviral or antibacterial drugs. Synonyms: [(2R,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-azido-6-carbamoyloxan-2-yl]methyl acetate; C-(2,3,4,6-TETRA-O-ACETYL-1-AZIDO-1-DEOXY-A-D-GALACTOPYRANOSYL)FORMAMIDE; c-(2,3,4,6-tetra-o-acetyl-1-azido-1-deoxy-alpha-d-galactopyranosyl)formamide; C-(2,3,4,6-Tetra-O-acetyl-1-azido-1-deoxy-alpha-D-galactopyranosyl)formamide?. CAS No. 180904-09-0. Molecular formula: C15H20N4O10. Mole weight: 416.34. | |
| C-(2,3,4,6-Tetra-O-acetyl-1-bromo-1-deoxy-b-D-galactopyranosyl)formamide | C-(2,3,4,6-Tetra-O-acetyl-1-bromo-1-deoxy-b-D-galactopyranosyl)formamide, an extensively researched and promising biomedical compound, exhibits immense potential for therapeutic applications. With its commendable prowess as a glycosylation reagent in synthesizing glycosides, oligosaccharides, and bioactive molecules, this exceptional product assumes a pivotal role in drug development. Synonyms: [(2R,3S,4S,5R,6S)-3,4,5-Triacetyloxy-6-bromo-6-carbamoyloxan-2-yl]methyl acetate; SCHEMBL8946300; C-(2,3,4,6-TETRA-O-ACETYL-1-BROMO-1-DEOXY-beta-D-GALACTOPYRANOSYL)FORMAMIDE. CAS No. 159895-07-5. Molecular formula: C15H20BrNO10. Mole weight: 456.3. | |
| C-(2,3,4,6-Tetra-O-acetyl-1-hydroxy-b-D-galactopyranosyl)formamide | C-(2,3,4,6-Tetra-O-acetyl-1-hydroxy-b-D-galactopyranosyl)formamide is a compound used in the research of various diseases playing a crucial role in targeting specific cellular pathways associated with compound resistance and cancer progression. Synonyms: [(2R,3S,4S,5R,6R)-3,4,5-triacetyloxy-6-carbamoyl-6-hydroxyoxan-2-yl]methyl acetate; C-(2,3,4,6-TETRA-O-ACETYL-1-HYDROXY-BETA-D-GALACTOPYRANOSYL) FORMAMIDE; C-(2,3,4,6-Tetra-O-acetyl-1-hydroxy-beta-D-galactopyranosyl)formamide?. CAS No. 189633-60-1. Molecular formula: C15H21NO11. Mole weight: 391.33. | |
| C-(2,3,4-Tri-O-acetyl-1-hydroxy-b-D-galactopyranosyl)formamide | C-(2,3,4-Tri-O-acetyl-1-hydroxy-b-D-galactopyranosyl)formamide is a biomedical product used for the study of certain diseases. It acts as a formamide derivative of galactose, which exhibits potential antitumor activity against various cancer types. CAS No. 189633-66-7. Molecular formula: C12H17NO9. Mole weight: 319.3. | |
| C3bot (154-182) | C3bot (154-182) is a transferase-deficient neurotrophic fragment of clostridial C3 protein. It promotes axonal and dendritic growth and branching of hippocampal neurons at submicromolar concentrations and promotes reinnervation of target tissues in organotypical hippocampal/entorhinal slice cultures. It reduces levels of active neuronal RhoA by a non-enzymatic mechanism and enhances functional recovery and regeneration in a mouse model of spinal cord injury. Synonyms: C3bot (154-182); 1246280-79-4. CAS No. 1246280-79-4. Molecular formula: C137H221N37O40S. Mole weight: 3058.54. | |
| Calcium-D-arabonate | Calcium-D-arabonate is a pivotal compound, used for the research of calcium inadequacies and skeletal ailments such as osteoporosis, osteomalacia and analogous afflictions. Synonyms: Calcium arabinoate; 22373-09-7; Calcium D-Arabonate; calcium d-arabinonate; CALCIUMD-ARABONATE; Arabinonic acid, Ca salt; 7546-24-9; D-Arabinonic acid, calcium salt (2:1); NSC-64721; 7AAL3Z6OQY; Arabinonic acid, calcium salt (2:1); calcium; (2S,3R,4R)-2,3,4,5-tetrahydroxypentanoate; Calcium-D-arabinoate; Calcium di-D-arabinonate; D-Arabinonic acid calcium salt; UNII-7AAL3Z6OQY; EINECS 244-940-1; SCHEMBL16564570; AMY32677; AKOS015896822; NSC 224305; CS-0209026; D97821; Q27266817. CAS No. 22373-09-7. Molecular formula: C5H9O6 Ca. Mole weight: 205.20. | |
| Calcium gluconate | Gluconate Calcium is a calcium supplement used in crop pesticide formulations and also in the treatment of too little calcium in the blood. Synonyms: Calcium D-gluconate; 2,3,4,5,6-Pentahydroxycaproic acid hemicalcium salt; D-Gluconic acid, calcium salt (2:1); Gluconic acid, calcium salt (2:1), D-; Biocal; Calcicol; Calciofon; Calcipur; Calcium D-gluconate; Calcium hexagluconate; Calglucol; Calglucon; Dragocal; Ebucin; Glucal; Glucobiogen; Kalpren; Novocal. Grades: ≥95%. CAS No. 299-28-5. Molecular formula: C12H22CaO14. Mole weight: 430.37. | |
| Calcium lactobionate | Calcium lactobionate, known for its significant biomedical applications, acting as an indispensable excipient. It plays a vital role in fortifying compound formulations, thereby bolstering their steadfastness and optimizing their delivery to target areas. Synonyms: 4-O-b-D-Galactopyranosyl-D-gluconic acid calcium salt; Calcium galactogluconate. CAS No. 5001-51-4. Molecular formula: C12H21O12 Ca. Mole weight: 377.33. | |
| Calcium L(-)-arabonate tetrahydrate | Calcium L(-)-arabonate tetrahydrate is a compound known for its applications in studying calcium deficiencies. Its pivotal role resides in preserving optimal calcium balance within the biological system. Synonyms: L(-)-Arabonic acid calcium salt. | |
| Calcium-L(-)-arabonate tetrahydrate | Calcium-L(-)-arabonate tetrahydrate is an esteemed pharmaceutical compound, manifesting exceptional prowess in studying and precluding maladies stemming from calcium insufficiency. Its profound efficacy as a supplemental source of calcium fosters the fortification of osseous vitality. Synonyms: L(-)-Arabonic acid calcium salt. Molecular formula: C10H26CaO16. Mole weight: 442.38. | |
| Calcium L-threonate | Empowered with remarkable and expedited absorptive traits, Calcium L-Threonate emerging as an extraordinary entity in the research of calcium supplements. This unique compound can be used in research of osteoporosis and bone fractures. Synonyms: L-Threonic acid calcium salt; (2R, 3S)-2,3,4-Trihydroxbutyric acid hemicalcium salt. CAS No. 70753-61-6. Molecular formula: C8H14CaO10. Mole weight: 310.27. | |
| Calystegine A3 | Calystegine A3, a biomedically significant natural compound, displays remarkable potency in extensive biomedical research. Its distinct characteristics have been duly recognized for studying specific neurologic ailments, including the renowned Alzheimer's disease. Through meticulous analysis, Calystegine A3 is particularly noteworthy for its pronounced inhibitory properties targeting crucial enzymes associated with the development of neurodegenerative conditions. Synonyms: [1R-(2-endo,3-exo)]-8-Azabicyclo[3.2.1]octane-1,2,3-triol; Calystegin A3; (+)-Calystegine A3; 8-Azabicyclo[3.2.1]octane-1,2,3-triol, (1R,2S,3R,5R)-. Grades: ≥95%. CAS No. 131580-36-4. Molecular formula: C7H13NO3. Mole weight: 159.18. | |
| Calystegine A5 | Calystegine A5 is an extraordinary natural alkaloid obtained from diverse botanical sources, exhibiting remarkable potency in the suppression of glycosidases. This outstanding attribute renders Calystegine A5 a highly promising tool for the research of Type 2 diabetes. Synonyms: Calystegine A5; Calystegin A5; 165905-26-0; (1R,3S,4S,5R)-8-AZABICYCLO[3.2.1]OCTANE-1,3,4-TRIOL; 8-Azabicyclo(3.2.1)octane-1,3,4-triol, (1R,3S,4S,5R)-; CHEMBL3233943; AKOS040735614. CAS No. 165905-26-0. Molecular formula: C7H13NO3. Mole weight: 159.18. | |
| Calystegine B1 | Calystegine B1 is an exceedingly powerful naturally occurring alkaloid, garnering immense attention for its prowess in obstructing diverse enzymes. This compound has proven instrumental in studying an array of afflictions like cancer, neurodegenerative pathologies as well as viral invasions. Synonyms: Calystegine B1; 127414-86-2; (1R,2S,3R,5S,6R)-8-AZABICYCLO[3.2.1]OCTANE-1,2,3,6-TETROL; Calystegine B(1); 8-azabicyclo[3.2.1]octane-1,2,3,6-tetrol; DTXSID20925887; AKOS040736062; FS-6673; 8-Azabicyclo(3.2.1)octane-1,2,3,6-tetrol, (1R,2S,3R,5S,6R)-rel-. CAS No. 127414-86-2. Molecular formula: C7H13NO4. Mole weight: 175.18. | |
| Calystegine B2 | Calystegine B2 is a bioactive compound known for its potential therapeutic properties in studying neurodegenerative diseases, such as Alzheimer's and Parkinson's. Extensive research has revealed its ability to inhibit enzymes involved in the progression of these diseases, making it a promising candidate for drug development. Synonyms: (1R,2S,3R,4S,5R)-8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol; Nortropanoline. CAS No. 127414-85-1. Molecular formula: C7H13NO4. Mole weight: 175.19. | |
| Calystegine B3 | Calystegine B3 is a highly potent natural inhibitor with widespread application encompassing the extensive research in targeting the debilitating neurodegenerative conditions, namely Alzheimer's and Parkinson's diseases. Synonyms: 8-Azabicyclo(3.2.1)octane-1,2,3,4-tetrol, (1R,2R,3R,4S,5R)-; 2-Epicalystegine B2; (+)-Calystegine B3; (1R,5R)-8-Azabicyclo[3.2.1]octane-1,2alpha,3alpha,4beta-tetrol; Calystegin B3; 8-Azabicyclo(3.2.1)octane-1,2,3,4-tetrol, (2-exo,3-exo,4-endo)-(+)-. Grades: >98%. CAS No. 178231-95-3. Molecular formula: C7H13NO4. Mole weight: 175.19. | |
| Calystegine B4 | Calystegine B4 is a potent natural compound found in various plants exhibiting promising applications in the study of neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: Calystegine B4; 184046-85-3; (1R,2S,3R,4R,5R)-8-azabicyclo[3.2.1]octane-1,2,3,4-tetrol; CHEMBL3233945; 8-Azabicyclo(3.2.1)octane-1,2,3,4-tetrol, (1R,2S,3R,4R,5R)-; 8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol, (1R,2S,3R,4R,5R)-; (-)-Calystegine B4; Q29YLG74LW; Calystegine B4 - 90% min; DTXSID501317306; BDBM50002909; 8-Azabicyclo[3.2.1]octane-1,2,3,4-tetrol, (2-endo,3-exo,4-exo)-(-)-. CAS No. 184046-85-3. Molecular formula: C7H13NO4. Mole weight: 175.18. | |
| Calystegine N1 | Calystegine N1 is a highly potent inhibitor assuming a pivotal and indispensable function in the research of diverse ailments including cancer, viral infections and neurodegenerative afflictions. | |
| Camidanlumab | Camidanlumab is a monoclonal antibody targeting CD25, which is expressed on activated T cells. Camidanlumab can be used in the synthesis of ADC Camidanlumab tesirine, which is investigated for the treatment of lymphoma and leukemia. Synonyms: HuMax-TAC. CAS No. 921618-45-3. | |
| Canagliflozin Related Impurity 9 | an impurity of Canagliflozin. Synonyms: (3R, 4S, 5R, 6R) -3, 4, 5-Tris ( (trimethylsilyl) oxy) -6- ( ( (trimethylsilyl) oxy) methyl) tetrahydro-2h-pyran-2-o. Grades: > 95%. CAS No. 32384-65-9. Molecular formula: C18H42O6Si4. Mole weight: 466.86. | |
| Canakinumab | Canakinumab is a recombinant human anti-IL-1β monoclonal antibody used for the treatment of immune disorders such as rheumatoid arthritis and cryopyrin-associated periodic syndrome (CAPS). Synonyms: Ilaris; ACZ 885; ACZ885. CAS No. 914613-48-2. | |
| Canertinib | Canertinib is an experimental drug candidate for the treatment of cancer. It is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 = 0.8 nM), HER-2 (IC50 = 19 nM) and ErbB-4 (IC50 = 7 nM). Synonyms: CI-1033; PD-183805; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide; N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide; 2-propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-. Grades: >98%. CAS No. 267243-28-7. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Canfosfamide | Canfosfamide hydrochloride is the hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation. S-transferase P1-1 is an enzyme that is overexpressed in many human malignancies. Synonyms: TELCYTA; TLK286; TLK 286; TLK-286. CAS No. 158382-37-7. Molecular formula: C26H40Cl4N5O10PS. Mole weight: 787.47. | |
| Caplacizumab | Caplacizumab is a humanized anti-von Willebrand factor (vWF) antibody that inhibits interaction between vWF multimers and platelets. Caplacizumab can be used for the treatment of thrombotic thrombocytopenic purpura (TTP). Synonyms: Cablivi; ALX-0681; ALX-0081. CAS No. 915810-67-2. | |
| Caracemide | Caracemide is an agent derived from acetohydroxamic acid. It has potential antineoplastic activity. Caracemide can inhibit ribonuclease reductase, resulting in decreased DNA synthesis and tumor growth. But in Feb 1995, Phase II for Cancer in USA was discontinued. Uses: Cancer. Synonyms: NSC 253272; NSC253272; NSC-253272; N-(methylcarbamoyl)-N-((methylcarbamoyl)oxy)acetamide. Grades: 98%. CAS No. 81424-67-1. Molecular formula: C6H11N3O4. Mole weight: 189.17. | |
| Carbazeran | Carbazeran is an AO (Aldehyde oxidase) substrate. It is a phosphodiesterase PDE-II and PDE-III inhibitor that can produce concentration-dependent positive inotropic responses. Carbazeran shows inotropic effect in vivo with EC50 value of 100 μM.Meanwhile, Carbazeran also shows chronotropic effect in vivo. Synonyms: UK 31557; UK-31557; UK31557; UK 31,557; UK-31,557; UK31,557; N-Ethylcarbamic Acid 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl Ester; Ethylcarbamic Acid 1-(6,7-Dimethoxy-1-phthalazinyl)-4-piperidinyl Ester. Grades: 95%. CAS No. 70724-25-3. Molecular formula: C18H24N4O4. Mole weight: 360.41. | |
| Carbenoxolone disodium | The sodium salt form of Carbenoxolone, which has been found to be an anti-inflammatory glucocorticoid and could inhibit 11β-hydroxysteroid dehydrogenase. Uses: Anti-ulcer agents. Synonyms: (3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium. Grades: ≥98% by HPLC. CAS No. 7421-40-1. Molecular formula: C34H48Na2O7. Mole weight: 614.72. | |
| Carbocloral | Carbocloral is a bio-active chemical compound and is used as sedative and hypnotic drug. Uses: Carbocloral is used as sedative and hypnotic drug. Synonyms: CI-336; CI 336; CI336; CN-16146; CN16146; CN 16146; NSC-33077; NSC33077; NSC33077; N-(2,2,2-trichloro-1-hydroxy-ethyl)carbamic acid ethyl ester; Chloralurethane; Prodorm; Uraline. Grades: 98%. CAS No. 541-79-7. Molecular formula: C5H8Cl3NO3. Mole weight: 236.48. | |
| Carboxyamidotriazole orotate | Carboxyamidotriazole orotate (CTO) is the orotate salt form of carboxyamidotriazole (CAI), an orally bioavailable small molecule with potential antiangiogenic and antiproliferative activities. Carboxyamidotriazole binds to and inhibits non-voltage-operated calcium channels, blocking both Ca2+ influx into cells and Ca2+ release from intracellular stores, resulting in the disruption of calcium channel-mediated signal transduction. CAI inhibits PI3 activity and vascular endothelial growth factor (VEGF) signaling. This may inhibit endothelial proliferation, tumor cell growth, invasion and metastasis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Synonyms: L-651582 Orotate; CAI Orotate; CTO; 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, compd. with 5-amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]-1H-1,2,3-triazole-4-carboxamide (1:1); 2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid 5-amino-1-[3,5-dichloro-4-(4-chlorobenzoyl)benzyl]-1H-1,2,3-triazole-4-carboxamide (1:1). Grades: ≥90%. CAS No. 187739-60-2. Molecular formula: C22H16Cl3N7O6. Mole weight: 580.76. | |
| Cardionogen 1 | Cardionogen 1 has been found to be a Wnt signaling modulator that could affect cardiomyocyte generation. Synonyms: 6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole. Grades: ≥99% by HPLC. CAS No. 577696-37-8. Molecular formula: C13H14N4OS. Mole weight: 274.34. | |
| Carlumab | Carlumab is a humanized anti-CCL2 (chemokine ligand 2) monoclonal antibody. Carlumab binds to CCL2 and inhibits angiogenesis and proliferation of tumor cells. Synonyms: CNTO 888. CAS No. 915404-94-3. | |
| CART (55-102) (human) | Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Val-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys47); L-valyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grades: ≥95%. CAS No. 214050-22-3. Molecular formula: C225H365N65O65S7. Mole weight: 5245.18. | |
| CART (55-102) (rat) | Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Uses: Appetite suppressant. Synonyms: H-Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu-OH (Disulfide bridge: Cys14-Cys32, Cys20-Cys40, Cys34-Cys37); L-isoleucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-alpha-glutamyl-L-lysyl-L-lysyl-L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-arginyl-L-isoleucyl-glycyl-L-lysyl-L-leucyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-L-threonyl-L-seryl-L-cysteinyl-L-asparagyl-L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-lysyl-L-cysteinyl-L-leucine (14->32),(20->40),(34->47)-tris(disulfide). Grades: ≥95%. CAS No. 209615-79-2. Molecular formula: C226H367N65O65S7. Mole weight: 5259.21. | |
| CART (62-76) (rat, human) | Cocaine- and amphetamine-regulated transcript (CART) is a neuropeptide protein with potent appetite-suppressing activity. It inhibits normal and starvation-induced feeding and blocks the neuropeptide Y-induced feeding response. Synonyms: H-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-OH; L-tyrosyl-glycyl-L-glutaminyl-L-valyl-L-prolyl-L-methionyl-L-cysteinyl-L-alpha-aspartyl-L-alanyl-glycyl-L-alpha-glutamyl-L-glutaminyl-L-cysteinyl-L-alanyl-L-valine; Cocaine and amphetamine-regulated transcript (62-76) (rat, human). Grades: ≥90%. CAS No. 210978-19-1. Molecular formula: C64H99N17O23S3. Mole weight: 1570.77. | |
| Carubicin HCl | Cas No. 52794-97-5. | |
| CASIN | CASIN is a selective GTPase Cdc42 inhibitor (IC50=2 uM), reducing active levels of Cdc42 in aged hematopoietic stem cells. Uses: Cdc42 gtpase inhibitor. Synonyms: 2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol. Grades: >98%. CAS No. 425399-05-9. Molecular formula: C20H22N2O. Mole weight: 306.41. | |
| Casopitant | Casopitant mesylate is the mesylate salt of a centrally-acting neurokinin 1 (NK1) receptor antagonist with antidepressant and antiemetic activities. Casopitant competitively binds to and blocks the activity of the NK1 receptor, thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in antiemetic effects. SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK1 receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. Uses: Antiemetics. Synonyms: GW679769; GW 679769; GW-679769; Zunrisa; Rezonic; 4-(4-Acetylpiperazin-1-yl)-N-{1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide. CAS No. 414910-27-3. Molecular formula: C30H35F7N4O2. Mole weight: 616.62. | |
| (+)-Casuarine | (+)-Casuarine is an efficacious inhibitory molecule, exhibiting extraordinary prowess in its antiviral and antifungal workings. Positioned adeptly within the biomedical study realm, this compound manifests magnificent therapeutic potential against pathologies instigated by herpes simplex, influenza viruses, and an array of fungi variants. CAS No. 159440-57-0. Molecular formula: C8H15NO5. Mole weight: 205.21. | |
| Casuarine-6-O-a-D-glucoside | Casuarine-6-O-a-D-glucoside is a naturally occurring compound derived from Casuarina trees, holding immense potential in the biomedical industry, specifically development. Extensive studies have revealed its profound efficacy in studying an array of afflictions, including cancer and inflammation. Molecular formula: C14H25NO10. Mole weight: 367.35. | |
| Catechol a-D-glucopyranoside | Catechol a-D-glucopyranoside is an extensively researched compound predominantly employed , exhibiting remarkable prospects for potential researchs targeting neurodegenerative conditions as well as specific malignancies. Molecular formula: C12H16O7. Mole weight: 272.25. | |
| CAY10404 | CAY10404 is a potent, selective COX-2 inhibitor. Synonyms: CAY 10404; CAY-10404; CAY10404; 3-[4-(methylsulfonyl)phenyl]-4-phenyl-5-(trifluoromethyl)-isoxazole. CAS No. 340267-36-9. Molecular formula: C17H12F3NO3S. Mole weight: 367.4. | |
| CAY10416 | CAY10416 is a dual COX-2/5-LO inhibitor. Synonyms: CHEMBL423638; CAY10416; CHEMBL 423638; CAY 10416; CHEMBL-423638; CAY-10416; ; 43919-96-8; 3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole; 3-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-(4-(methylsulfonyl)phenyl)-5-phenyl-1H-pyraz. CAS No. 443919-96-8. Molecular formula: C29H29FN2O5S. Mole weight: 536.6. | |
| CAY10434 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10434 is a selective inhibitor of the 20-HETE synthase CYP4A11 displaying an IC50 value of 8.8 nM when tested in human renal microsomes. It is nearly 200 times less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes. Synonyms: CAY 10434; CAY-10434. Grades: ≥98%. CAS No. 769917-29-5. Molecular formula: C17H25N3O. Mole weight: 287.4. | |
| CAY10462 | 20-HETE is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family. CAY10462 is the hydrochloride salt form of CAY10434. It is a selective inhibitor of the 20-HETE synthase CYP4A11, which exhibits an IC50 of 8.8 nM when tested in human renal microsomes. Synonyms: CAY 10462; CAY-10462. Grades: ≥98%. CAS No. 502656-68-0. Molecular formula: C17H25N3O·2HCl. Mole weight: 360.3. | |
| CAY10464 | The aryl hydrocarbon receptor (AHR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics. CAY10464 is a potent and selective AhR antagonist with a Ki of 1.4 nM. It is inactive as an estrogen receptor ligands even used at 100 μM. Synonyms: CAY 10464; CAY-10464. Grades: ≥98%. CAS No. 688348-37-0. Molecular formula: C15H12Cl2O. Mole weight: 279.2. | |
| CAY10465 | The aryl hydrocarbon receptor (AHR) is a ligand-dependent intracellular transcription factor. CAY10465 is an analog of resveratrol which acts as a potent and selective AHR receptor agonist with Ki of 0.2 nM. It is inactive as a ligand for the estrogen receptor. Synonyms: CAY 10465; CAY-10465. Grades: ≥98%. CAS No. 688348-33-6. Molecular formula: C15H9Cl2F3. Mole weight: 317.1. | |
| CAY10595 | Chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) is a G-protein coupled receptor that binds to the ligand prostaglandin D2 (PGD2).The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. CAY10595 is a mixture of isomers which acts as a potent CRTH2/DP2 receptor antagonist with Ki of 10 nM. Synonyms: CAY 10595; CAY-10595. Grades: ≥97%. CAS No. 916047-16-0. Molecular formula: C20H13Cl2FN2O5. Mole weight: 451.2. | |
| CAY10597 | The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. CAY10597, as a racemic mixture, is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki value of 37 nM. The R enantiomer is slightly more potent exhibiting Ki values of 23 and 22 nM at the human and murine CRTH2/DP2 receptor, respectively. Synonyms: CAY 10597; CAY-10597. Grades: ≥98%. CAS No. 916046-55-4. Molecular formula: C20H14ClFN2O5. Mole weight: 416.8. | |
| CB10-277 | CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups. Uses: Antineoplastic agents. Synonyms: CB10-277; CB10 277; CB10277; 1-p-carboxy-3,3-dimethylphenyltriazine. CAS No. 7203-91-0. Molecular formula: C9H11N3O2. Mole weight: 193.21. | |
| CB181963 | CB181963 shows excellent activity against MRSA strains resistant to other cephalosporins in both planktonic and biofilm cultures. It is a potent antistaphylococcal agent with better activity against MRSA. It may play a role in the treatment of staphylococcal infections, including those caused by MRSA and in the prophylaxis of biofilm-associated MSSA and MRSA infections. Uses: Cb181963 may play a role in the treatment of staphylococcal infections, including those caused by mrsa and in the prophylaxis of biofilm-associated mssa and mrsa infections. Synonyms: CB 181963; CB-181963; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7- ( ( (2Z) - (5-amino-1, 2, 4-thiadiazol-3-yl) ( (fluoromethoxy) imino) acetyl) amino) -3- ( (E) - ( (imino-1-piperazinylmethyl) methylhydrazono) methyl) -8-oxo-, (6R,7R)-. Grades: 98%. CAS No. 635292-67-0. Molecular formula: C19H24FN11O5S2. Mole weight: 569.59. | |
| CB-3705 | CB-3705 is a bio-active chemical compound. Synonyms: CB 3705; CB3705; 5,8-Dideazafolic acid; 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-benzoylamino}-pentanedioic acid. Grades: 98%. CAS No. 5854-11-5. Molecular formula: C21H21N5O6. Mole weight: 439.42. | |
| CB-7921220 | CB-7921220 is an adenylate cyclase inhibitor which is selective, reducing adenylyl cyclase type I and VI activity by 60% while having no effect on types II and V in Sf9 membranes stimulated by forskolin at a concentration of 100 μM. CB-7921220 has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6. Synonyms: CB7921220; CB 7921220; CB-7921220; 6-[(E)-2-(4-aminophenyl)ethenyl]pyridine-2-carboxylic acid. CAS No. 115453-99-1. Molecular formula: C14H12N2O2. Mole weight: 240.26. | |
| CBP501 | CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-specific phosphatase Cdc25C (cell division checkpoint 25 C); disruption of Cdc25C activity results in the inhibition of Cdc25C dephosphorylation of the mitotic cyclin-dependent kinase complex Cdc2/cyclin B, preventing entry into the mitotic phase of the cell cycle. Check for active clinical trials or closed clinical trials using this agent. Synonyms: CBP-501; CBP 501; H-D-Bpa-D-Ser-D-Trp-D-Ser-D-Phe(F5)-D-Cha-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-OH. CAS No. 565434-85-7. Molecular formula: C86H122F5N29O17. Mole weight: 1929.06. | |
| CBP-93872 | CBP-93872 is a G2 checkpoint inhibitor. CBP-93872 specifically abrogates the DNA double-stranded break (DSB)-induced G2 checkpoint through inhibiting maintenance. CBP-93872 is an inhibitor of maintenance of the DSB-specific G2 checkpoint and thus might be a strong candidate as the basis for a drug that specifically sensitizes p53-mutated cancer cells to DSB-inducing DNA damage therapy. Synonyms: CBP 93872; CBP93872; 1-amino-3-((2-bromo-4-methylphenyl)amino)propan-2-ol. Grades: 98%. CAS No. 67427-51-4. Molecular formula: C10H15BrN2O. Mole weight: 259.14. | |
| CBP-aminomethylenevancomycin | CBP-aminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP aminomethylenevancomycin. | |
| CBP-C1-aminomethylenevancomycin | CBP-C1-aminomethylenevancomycin is an analogue of vancomycin which overcomes the drug resistance and induces cell permeability. It significantly increases the antibacterial activity and decreases the side effects. Uses: Antibacterial agent. Synonyms: CBP C1 aminomethylenevancomycin. | |
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