BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CHZ868 | CHZ868 is a potent and selective type II JAK2 inhibitor (IC50 = 0.17 μM in EPOR JAK2 WT Ba/F3 cell). CHZ868 potently inhibited proliferation of cells expressing the JAK2V617F mutation or the TEL-JAK2 fusion. Synonyms: Acetamide, N-[4-[[2-[(2,4-difluorophenyl)amino]-1,4-dimethyl-1H-benzimidazol-5-yl]oxy]-2-pyridinyl]-; N-(4-{[2-(2,4-difluoroanilino)-1,4-dimethyl-1H-benzimidazol-5-yl]oxy}pyridin-2-yl)acetamide; N-[4-[2-[[2,4-bis(fluoranyl)phenyl]amino]-1,4-dimethyl-benzimidazol-5-yl]oxypyridin-2-yl]ethanamide. Grades: 98%. CAS No. 1895895-38-1. Molecular formula: C22H19F2N5O2. Mole weight: 423.42. |  |
| CI-680 | CI-680 is a bio-active chemical compound. Synonyms: 3-(p-(alpha-(p-Methoxyphenyl)beta-nitrostyryl)phenoxy)-N,N-dimethylpropylamine monocitrate; CI 680; CI680; 3-(4-(1-(4-Methoxyphenyl)-2-nitro-2-phenylethenyl)phenoxy)-N,N-dimethyl-1-propanamine, 2-hydroxy-1,2,3-propanetricarboxylate (1:1). Grades: 98%. CAS No. 56287-31-1. Molecular formula: C32H36N2O11. Mole weight: 624.64. | |
| Cianopramine hydrochloride | Cianopramine hydrochloride is the hydrochloride form of Cianopramine, which acts as a serotonin reuptake inhibitor and weak serotonin receptor antagonist. It is a tricyclic antidepressant and used for the treatment of depression. Uses: Cianopramine hydrochloride is a tricyclic antidepressant and used for the treatment of depression. Synonyms: 11-(3-Dimethylaminopropyl)-5,6-dihydrobenzo(b)(1)benzazepine-9-carbonitrile hydrochloride; Cianopramine HCl; Ro 112465 hydrochloride; Ro-11-2465 hydrochloride. Grades: 98%. CAS No. 66834-20-6. Molecular formula: C20H24ClN3. Mole weight: 341.88. | |
| Cibisatamab | Cibisatamab is an anti-carcinoembryonic antigen (CEA) and anti-CD3 bispecific monoclonal antibody used for cancer therapy. Cibisatamab binds to both T cells and CEA-expressing tumor cells, which cross-links the T cells with the tumor cells. Synonyms: CEA-TCB. CAS No. 1855925-27-7. | |
| Ciclopirox β-D-Glucuronide | Ciclopirox β-D-Glucuronide is a metabolite of Ciclopirox. Synonyms: 1-[(6-Cyclohexyl-4-methyl-2-oxo-1(2H)-pyridinyl)oxy]-1-deoxy-β-D-glucopyranuronic Acid. Grades: > 95%. CAS No. 79419-54-8. Molecular formula: C18H25NO8. Mole weight: 383.40. | |
| Ciclopirox-D11 D-glucuronide | Ciclopirox-D11 D-glucuronide is a renowned pharmaceutical compound manifesting its exceptional proclivity towards research of an assortment of fungal infections owing to its robust antifungal attributes. By obstructing the development of ergosterol within the cell membrane of fungi, this compound demonstrates inhibitory efficacy in eradicating afflictions attributable to Aspergillus, Candida and dermatophyte species in a laudable manner. Molecular formula: C18H14NO8D11. Mole weight: 394.47. | |
| CID 1067700 | CID 1067700 is a Rab7 GTPase inhibitor exhibiting significant inhibitory potency against Rab7 nucleotide binding with nanomolar inhibitor (Ki) values and an inhibitory response of ≥97% for BODIPY-GTP and BODIPYGDP binding (Ki values 13 nM and 19 nM, and EC50 values 11 and 21 nM, respectively). CID 1067700 is a competitive guanine nucleotide binding inhibitor. Synonyms: CID 1067700; CID1067700; 2-(3-benzoylthioureido)-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran-3-carboxylic acid; MLS000673908; ML282; SMR000297947; CID-1067700. Grades: 99%. CAS No. 314042-01-8. Molecular formula: C18H18N2O4S2. Mole weight: 390.48. | |
| Ciliobrevin A | Ciliobrevin A is a Hedgehog (Hh) pathway inhibitor that blocks Hh pathway activation and decreases Smo ciliary accumulation in a constitutively active Hh cell line. It perturbs primary cilia formation, leads to disruption of Gli1/Gli2 activity, and suppresses primary cilia-related protein intraflagellar transport protein IFT88 expression. It inhibits cell proliferation, invasion and migration ability in human chondrosarcoma. Synonyms: HPI-4; Hedgehog Pathway Inhibitor 4; (E)-3-(2,4-dichlorophenyl)-3-oxo-2-(4-oxo-3,4-dihydroquinazolin-2(1H)-ylidene)propanenitrile. Grades: >98%. CAS No. 302803-72-1. Molecular formula: C17H9Cl2N3O2. Mole weight: 358.18. | |
| Cimicifugoside | Cimicifugoside is an organic constituent prevalent in various Cimicifuga species, facilitating the research and development of pharmaceutical solutions targeting menopausal indications encompassing vexatious hot flashes and perturbed emotional states. Its unparalleled efficacy stems from its astute capacity to imitate the hormonal actions of estrogen. CAS No. 66176-93-0. Molecular formula: C37H54O11. Mole weight: 674.82. | |
| Cinchonidine | Cinchonidine is an alkaloid found in Cinchona officinalis. It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer of cinchonine. Cinchonidine is a weak inhibitor of serotonin transporter (SERT) with Kis of 330, 4.2, 36, 196, 15 μM for dSERT, hSERT, hSERT I172M, hSERT S438T, hSERT Y95F, respectively. Synonyms: (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](quinolin-4-yl)methanol; Cinchovatine; NSC 5364; α-Quinidine; (8α,9R)-Cinchonan-9-ol; (-)-Cinchonidine; (8S,9R)-Cinchonidine; (8α,9R)-Cinchonan-9-ol. Grades: >98%. CAS No. 485-71-2. Molecular formula: C19H22N2O. Mole weight: 294.39. | |
| Cinchonidine sulphate | Cinchonidine sulphate is the sulfate form of cinchonidine, which is an alkaloid found in Cinchona officinalis and Gongronema latifolium. It is used in asymmetric synthesis in organic chemistry. Uses: Cinchonidine sulphate is used in asymmetric synthesis in organic chemistry. Synonyms: Cincholidine sulfate; (8-alpha,9R)-Cinchonan-9-ol sulfate (2:1) (salt); Cinchonan-9-ol, (8-alpha,9R)-, sulfate (2:1) (salt). Grades: 98%. CAS No. 524-61-8. Molecular formula: C38H46N4O6S. Mole weight: 686.86. | |
| Cindunistat | Cindunistat is a potent and oral selective iNOS inhibitor, potentially useful in patients with symptomatic osteoarthritis of the knee. Uses: Nitric oxide synthase type ii inhibitor. Synonyms: SC-84250; SC 84250; SC84250; SD-6010; SD 6010; SD6010; S-(2-(Acetimidoylamino)ethyl)-2-methyl-L-cysteine. Grades: ≥98%. CAS No. 364067-22-1. Molecular formula: C8H17N3O2S. Mole weight: 219.30. | |
| CInQ-03 | CInQ-03 is a novel and specific MEK inhibitor both in vitro and in vivo. Synonyms: CInQ 03; CInQ03. CAS No. 500272-80-0. Molecular formula: C22H12ClN5O. Mole weight: 397.82. | |
| Ciprofibrate-O-β-Glucuronide | Ciprofibrate-O-β-Glucuronide is a derivative of Ciprofibrate. Ciprofibrate is a hypolipemic agent that is structurally related to Clofibrate. Ciprofibrate works primarily by stimulating lipoprotein lipases and hepatic lipases in the breakdown of triglyceride and cholesterol. Synonyms: 1-[2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoate]-β-D-glucopyranuronic Acid; Ciprofibrate glucuronide. Grades: > 95%. CAS No. 102623-15-4. Molecular formula: C19H22Cl2O9. Mole weight: 465.28. | |
| cis-ACBD | cis-ACBD has been found to be a potent inhibitor of EAAT. Synonyms: cis-1-Aminocyclobutane-1,3-dicarboxylic acid. Grades: ≥98% by HPLC. CAS No. 73550-55-7. Molecular formula: C6H9NO4. Mole weight: 159.14. | |
| cis-Zeatin-9-glucoside | cis-Zeatin-9-glucoside is an influential compound, renowned for its anti-inflammatory prowess and astounding antioxidant capabilities, used in the research of cancer, neurodegenerative afflictions and inflammatory predicaments. Synonyms: 6-((Z)-4-hydroxy-3-methylbut-2-enylamino)-9-b-Dglucopyranosylpurine. CAS No. 169565-72-4. Molecular formula: C16H23N5O6. Mole weight: 381.38. | |
| cis-Zeatin-o-glucoside | cis-Zeatin-o-glucoside is a foundational element with anti-inflammatory attributes, thereby affording its relentless deployment in the research of protracted inflammatory ailments, such as rheumatoid arthritand Crohn's disease. Possessing the distinct power to infiltrate into specific enzymatic conduits, this pharmaceutical compound orchestrates a meritorious suppression of the inflamed retort. Synonyms: 6-((Z)-4-b-D-glucopyranosyloxy-3-methylbut-2-enylamino)purine. CAS No. 71866-93-8. Molecular formula: C16H23N5O6. Mole weight: 381.38. | |
| CITCO | CITCO is a constitutive androstane receptor (CAR) agonist (EC50 = 49 nM), inducing nuclear translocation of human CAR in hepatocytes, followed by increased expression of CAR-regulated genes, including several cytochrome P450 isoforms. Uses: Constitutive androstane receptor (car) agonist. Synonyms: 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime. Grades: ≥98%. CAS No. 338404-52-7. Molecular formula: C19H12Cl3N3OS. Mole weight: 436.74. | |
| Cixutumumab | Cixutumumab is a humanized anti-IGF-1R monoclonal antibody for the treatment of solid tumors. Cixutumumab selectively binds to membrane-bound IGF-1R, preventing the binding of the natural ligand IGF-1 and the subsequent activation of PI3K/AKT signaling pathway. Synonyms: IMC-A12; NSC742460. CAS No. 947687-12-9. | |
| CJ-15161 | CJ-15161 is a κ-opioid receptor agonist. Synonyms: CJ 15161; CJ15161; 4-(((S)-2-((S)-3-Hydroxypyrrolidin-1-yl)-1-phenylethyl)(methyl)amino)-N-propylbenzamide. CAS No. 204970-97-8. Molecular formula: C23H31N3O2. Mole weight: 381.52. | |
| CK0106023 | CK0106023 was specific inhibitor of KSP. In tumor-bearing mice, CK0106023 exhibited antitumor activity comparable to or exceeding that of paclitaxel and caused the formation of monopolar mitotic figures identical to those produced in cultured cells. KSP was most abundant in proliferating human tissues and was absent from cultured postmitotic neurons. Synonyms: CK 0106023; CK-0106023; N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide. CAS No. 336115-72-1. Molecular formula: C30H32BrClN4O2. Mole weight: 595.97. | |
| CK-102 | CK-102 is a bio-active chemical compound. Synonyms: CK102; CK 102; 3,4-Dimethyl-9(10H)-acridone. Grades: 98%. CAS No. 6236-97-1. Molecular formula: C15H13NO. Mole weight: 223.27. | |
| CK2 inhibitor 10 | CK2 inhibitor 10 is a potent and ATP-competitive inhibitor of protein kinase (CK2; IC50 values of 32 nM and 46 nM for CK2α and CK2α' respectively). Compound 10 dose-dependently inhibits the kinases. It exhibits potent cytotoxicity towards lung cancer cells A549, colorectal cancer cells HCT-116, and breast cancer cells MCF-7. Synonyms: CK2-IN-3b; 4-(2-(4-methoxybenzamido)thiazol-5-yl)benzoic acid. Grades: 99%. CAS No. 1361229-76-6. Molecular formula: C18H14N2O4S. Mole weight: 354.38. | |
| CK-492B | CK-492B is a bio-active chemical compound. Synonyms: CK492B; CK 492B; 1,4-Bis-(3-(1-adamantyl carbamylguanidino)propyl)piperazine. Grades: 98%. CAS No. 64169-11-5. Molecular formula: C36H66N10O8S2. Mole weight: 831.11. | |
| CK-636 | CK-636 is an Arp2/3 complex inhibitor. CK-636 binds between Arp2 and Arp3, where it appears to block movement of Arp2 and Arp3 into their active conformation. CK-636 inserts into the hydrophobic core of Arp3 and alters its conformation. Synonyms: CK636; CK 636; CK-636; CK0944636; CK-0944636; CK 0944636. CAS No. 442632-72-6. Molecular formula: C16H16N2OS. Mole weight: 284.38. | |
| CK 666 | CK 666 has been found to be an inhibitor of the Arp2/3 complex and could also restrain actin polymerization. Synonyms: CK 666; CK666; CK-666; 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide. Grades: ≥99% by HPLC. CAS No. 442633-00-3. Molecular formula: C18H17FN2O. Mole weight: 296.34. | |
| CKD-516 HCl | CKD-516 is tubulin inhibitor for solid cancer, which was initiated phase 1 trial in Korea in 2010. CKD-516 selectively disrupted tubulin component of the endothelial cytoskeleton. Serial DCE-MRI showed a significant decrease in K-trans and IAUGC parameters from baseline at 4 h (39.9 % in K-trans; -45.0 % in IAUGC) and at 24 h (-32.2 % in K-trans; -36.5 % in IAUGC), and a significant recovery at 48 h (22.9 % in K-trans; 34.8 % in IAUGC) following administration of CKD-516 at a 0.7-mg/kg dose. When the tumors were stratified according to the initial K-trans value of 0.1, tumors with a high K-trans?>?0.1 which was indicative of having well-developed pre-existing vessels, showed greater reduction in K-trans and IAUGC values. On histologic examination, the degree of necrosis of treated tumors was significantly greater than that of untreated tumors. In summary, CKD-516 is an effective VDA which results in rapid vascular shutdown by targeting the tubulin component of tumor vessels and thus leads to necrosis. Synonyms: Valecobulin hydrochloride; CKD516 hydrochloride; CKD 516 hydrochloride. CAS No. 1240321-53-2. Molecular formula: C26H29ClN6O5S. Mole weight: 573.07. | |
| CKI 7 dihydrochloride | CKI 7 is a CK1 inhibitor, and also inhibits SGK, S6K1 and MSK1. In combination with SB 431542, CKI 7 was shown to induce retinal cell differentiation from human ESCs and iPSCs. Synonyms: CKI-7 dihydrochloride; N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride. Grades: >98%. CAS No. 1177141-67-1. Molecular formula: C11H14Cl3N3O2S. Mole weight: 358.67. | |
| Clazakizumab | Clazakizumab is a monoclonal antibody directed against interleukin-6. Clazakizumab has been undergoing a clinical trial for the treatment of CABMR in recipients of a kidney transplant. Synonyms: ALD518; BMS-945429. CAS No. 1236278-28-6. | |
| Clindamycin B | Clindamycin B is a minor impuritiy of Clindamycin in bulk drug. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-1-methyl-2-pyrrolidinyl]carbonyl] amino]-1-thio-L-threo-α-D-galactooctopyranoside; (2S-trans)-Methyl 7-Chloro-6,7,8- trideoxy-6-[[(4-ethyl-1-methyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galac. Grades: > 95%. CAS No. 18323-43-8. Molecular formula: C17H31ClN2O5S. Mole weight: 410.96. | |
| Clindamycin B Palmitate | Clindamycin B Palmitate is an impurity in the synthesis of Clindamycin Palmitate Hydrochloride, a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial. Synonyms: (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[(4-ethyl-1-methyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-Hexadecanoate. Grades: > 95%. CAS No. 68206-99-5. Molecular formula: C33H61ClN2O6S. Mole weight: 649.37. | |
| Clindamycin Heptadecanoate | Clindamycin Heptadecanoate is an impurity in the synthesis of Clindamycin Palmitate Hydrochloride, a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-Heptadecanoate. Grades: > 95%. CAS No. 1123211-69-7. Molecular formula: C35H65ClN2O6S. Mole weight: 677.42. | |
| Clindamycin Laurate | Clindamycin Laurate is an impurity in the synthesis of Clindamycin Palmitate Hydrochloride, a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial. Synonyms: (2S-trans)-Methyl 7-Chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-Dodecanoate. Grades: > 95%. CAS No. 763863-68-9. Molecular formula: C30H55ClN2O7S. Mole weight: 623.28. | |
| Clindamycin Myristate | Clindamycin Myristate is an impurity in the synthesis of Clindamycin Palmitate Hydrochloride, a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-Tetradecanoate. Grades: > 95%. CAS No. 1123211-66-4. Molecular formula: C32H59ClN2O6S. Mole weight: 635.34. | |
| Clindamycin palmitate hydrochloride | Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic. It is usually used to treat infections with anaerobic bacteria, but can also be used to treat protozoal diseases, such as malaria. It is a common topical treatment for acne and can be useful against some methicillin-resistant Staphylococcus aureus (MRSA) infections. Synonyms: Clindamycin palmitate hydrochloride. Grades: >98%. CAS No. 25507-04-4. Molecular formula: C34H63ClN2O6S.HCl. Mole weight: 699.85. | |
| Clindamycin Pentadecanoate | Clindamycin Pentadecanoate is an impurity in the synthesis of Clindamycin Palmitate Hydrochloride, a semi-synthetic antibiotic with high bioavailability. Clindamycin Palmitate is an antibacterial. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-Pentadecanoate. Grades: > 95%. CAS No. 1123211-67-5. Molecular formula: C33H61ClN2O6S. Mole weight: 649.37. | |
| Clindamycin Stearate | Clindamycin Stearate is an impurity of Clindamycin Palmitate, is a semi-synthetic antibiotic with high bioavailability. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-octadecanoate. Grades: > 95%. CAS No. 1123211-70-0. Molecular formula: C36H67ClN2O6S. Mole weight: 691.44. | |
| Clodronate | Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. This agent may control malignancy-associated hypercalcemia, inhibit osteolytic bone metastasis and decrease pain. Uses: Bone density conservation agents. Synonyms: Clodronic Acid; Acido clodronico; Dichloromethylidene diphosphonate; dichloromethylene-1,1-diphosphonic acid; Dichlormethylen-bis(phosphonsaeure). Grades: >98%. CAS No. 10596-23-3. Molecular formula: CH4Cl2O6P2. Mole weight: 244.89. | |
| Clodronate Disodium | Clodronic acid (INN) or clodronate disodium (USAN) is a first generation (non-nitrogenous) bisphosphonate. It is an anti-osteoporotic drug approved for the prevention and treatment of osteoporosis in post-menopausal women and men to reduce vertebral fractures, hyperparathyroidism, hypercalcemia in malignancy, multiple myeloma and fracture related pain because of its potent anti-inflammatory and analgesic effects shown as a reduction in inflammatory markers like IL-1β, IL-6, and TNF-alfa. Uses: Bone density conservation agents. Synonyms: Disodium clodronate; Clodronic acid disodium salt; Clasteon; Lodronate; Ostac; Bonefos; Clodronate disodium anhydrous. Grades: >98%. CAS No. 22560-50-5. Molecular formula: CH2Cl2Na2O6P2. Mole weight: 288.86. | |
| Clopidogrel acyl glucuronide | Clopidogrel acyl glucuronide is a metabolite of Clopidogrel, assuming a pivotal function in studying various cardiovascular afflictions including acute coronary syndrome. Molecular formula: C21H22ClNO8S. Mole weight: 483.92. | |
| Clorprenaline HCl | Clorprenaline hydrochloride is a β2-adrenergic receptor agonist. It is commonly used for the treatment of bronchial asthma, bronchitis and other respiratory diseases in clinical. Uses: Bronchodilator agents. Synonyms: N-Isopropyl-2-hydroxy-2-(o-chlorophenyl)ethylamine hydrochloride; Isoprophenamine. Grades: >98%. CAS No. 6933-90-0. Molecular formula: C11H17Cl2NO. Mole weight: 250.16. | |
| CLS-011A | CLS-011A is a small molecule used as an antineoplastic and eye disorder therapy. Study indicated its excellent tolerance. Uses: Antineoplastic and eye disorder therapy. Synonyms: CLS 011A. | |
| CM1 | CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grades: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34. | |
| CM 10 | CM 10 is an inhibitor of aldehyde dehydrogenase 1A (ALDH1A) inhibitor. It can induce a necroptotic phenotype and preferentially deplete CD133+ ovarian cancer stem cells in vitro. Synonyms: 2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol. Grades: ≥98% by HPLC. CAS No. 692269-09-3. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| CMG-101 | CMG-101 is a novel selective inhibitor of mTORC1/2. Studies suggest that CMG-101 would overcome the drug resistance of mTORC1 inhibitor through the activation of signal transduction pathways via mTORC2. CMG-101 is promisingly to be a antitumor drug. Uses: Potential antitumor drug. Synonyms: CMG101; CMG 101. | |
| CMP-N-acetylneuraminic acid 9-sp-biotin | | |
| CMP-N-acetylneuraminic acid sodium salt | CMP-N-acetylneuraminic acid sodium salt, a fundamental compound employed in the field of biomedicine, exhibits immense utility in the management of diverse ailments associated with compromised sialic acid metabolism, including sialuria and sialic acid storage diseases. Synonyms: CMP-NANA; Cytidine 5-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid; CMP-Neu5Ac. CAS No. 3063-71-6. Molecular formula: C20H30N4O16P Na. Mole weight: 636.43. | |
| CMP-N-glycolylneuraminic acid | CMP-N-glycolylneuraminic acid is a fundamental compound extensively used in the biomedical field, serving as an indispensable precursor in the research and development of diverse sialic acid derivatives, which wield significant influence over a plethora of intricate biological mechanisms. Synonyms: N-(2-hydroxyacetyl)-b-neuraminic acid 2-(hydrogen 5-cytidylate); CMP-NeuGc. CAS No. 98300-80-2. Molecular formula: C20H31N4O17P. Mole weight: 630.45. | |
| CMP-Pseudaminic acid | CMP-Pseudaminic acid is a compound of immense value, serving as a fundamental building block for the bioresearch and development of pseudaminic acid, a vital constituent of bacterial glycosylated proteins. By impeding enzymatic development, CMP-Pseudaminic acid reveals promising prospects for research of bacterial infections triggered by notorious pathogens like Campylobacter jejuni and Helicobacter pylori. Synonyms: CMP-Pse. Molecular formula: C22H32N5O15P. Mole weight: 637.49. | |
| Cochineal | Cochineal is a natural red dye derived from insects commonly used in the biomedical industry for its unique properties. It is utilized in various medications and studies involving cell imaging, histology, and immunology. Uses: Food coloring agents. Synonyms: Carmine. CAS No. 1343-78-8. Molecular formula: C22H20O13. Mole weight: 492.39. | |
| Codrituzumab | Codrituzumab is a humanized monoclonal antibody against Glypican-3 (GPC3). Codrituzumab binds to GPC3 and suppresses GPC3-expressing tumor cell growth. Synonyms: GC33; RO5137382. CAS No. 1365267-33-9. | |
| Colchicine EP impurity D | Colchicoside is a significantly toxic Colchicine analog with no anti-inflammatory properties. Synonyms: (S)-N-[3-(b-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; N-[(7S)-3-(b-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl]acetamide; 3-Demethylcolchicine glucoside. Grades: > 95%. CAS No. 477-29-2. Molecular formula: C27H33NO11. Mole weight: 547.55. | |
| Colitose | Colitose is an extensively applied biomedical compound renowned for its profound impact in studying colitis is a prevalent inflammatory bowel disease. Synonyms: 3,6-Dideoxy-L-xylo-hexose; L-Colitose. CAS No. 4221-05-0. Molecular formula: C6H12O4. Mole weight: 148.16. | |
| Compound 401 | Compound 401, a pyrimido-isoquinolinone compound, is a selective and cell-permeable inhibitor that has an reversible function on DNA-dependent protein kinase (DNA-PK). It is also a mammalian target of rapamycin (mTOR) with little affinity for 43 other com. Synonyms: 2-morpholin-4-ylpyrimido[2,1-a]isoquinolin-4-oneCompound 401; Compound-401; Compound401;168425-64-72-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-oneCHEMBL1792422-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-oneSCHEMBL10092321CTK4D2994S-7713; S 7713; S77132-(morpholin-4-yl)pyrimido[2,1-a]iso. Grades: >99 %. CAS No. 168425-64-7. Molecular formula: C16H15N3O2. Mole weight: 281.31. | |
| Conduritol D | Conduritol D is a versatile and essential compound in the dynamic compound realm, taking center stage in the research of metabolic disorders. This valuable compound exhibits unmatched proficiency as a foundational unit for synthesizing carbohydrate-based pharmaceuticals. Synonyms: (1R,2R,3S,4S)-rel-5-cyclohexene-1,2,3,4-tetrol. CAS No. 4782-75-6. Molecular formula: C6H10O4. Mole weight: 146.14. | |
| Congo Red | Congo Red is an acid secondary azo dye. It is a VGlut inhibitor and could decrease synaptic transmission in the dentate gyrus. It is an amyloid fibril-binding dye. It can be used to diagnose amyloidosis and used as a diagnostic test for the presence of amyloid in tissue sections. It inhibits the pancreatic islet cell toxicity of diabetes-associated amylin. Its excitation wavelength is 497 nm. It is also a general tissue stain for use as a cytoplasmic counterstain. It is also used in testing for hydrochloric acid in gastric contents and used to stain β sheet aggregates. Synonyms: 1-Naphthalenesulfonic acid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(2,1-diazenediyl)]bis[4-amino-, sodium salt (1:2); 1-Naphthalenesulfonic acid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis[4-amino-, disodium salt; C.I. Direct Red 28, disodium salt; Atlantic Congo Red; Atul Congo Red; Azocard Red Congo; Benzo Congo Red; Brasilamina Congo 4B; C.I. 22120; C.I. Direct Red 28; Congo red disodium salt; Cotton Red L; Diacotton Congo Red; Direct Congo Red; Erie Congo 4B; Haemomedical; Haemonorm; Hemorrhagyl; Kayaku Congo Red; Mitsui Congo Red; Peeramine Congo Red; Red K (dye); Solucongo; Sugai Congo Red; Tertrodirect Red C; Trisulfon Congo Red; Vondacel Red CL. Grades: ≥98% by HPLC. CAS No. 573-58-0. Molecular formula: C32H22N6Na2O6S2. Mole weight: 696.66. | |
| Conquinine | Conquinine is a Cytochrome P450 2D6 inhibitor. It is a dextrorotatory stereoisomer of quinine extracted from the bark of the Cinchona tree and similar plant species. It is an alkaloid with class 1A antiarrhythmic and antimalarial effects. It also blocks muscarinic and alpha-adrenergic neurotransmission. It stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thus inhibiting the sodium influx required for the initiation and conduction of impulses resulting in an increase of the threshold for excitation and decreased depolarization during phase 0 of the action potential. It acts primarily as an intra-erythrocytic schizonticide through association with the heme polymer (hemazoin) in the acidic food vacuole of the parasite thereby preventing further polymerization by heme polymerase enzyme. Uses: Conquinine is an alkaloid with class 1a antiarrhythmic and antimalarial effects. it also blocks muscarinic and alpha-adrenergic neurotransmission. Synonyms: Quinidine;Chinidin;Pitayine;(+)-Quinidine;Quinidex;Chinidin;(S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol. Grades: 98%. CAS No. 56-54-2. Molecular formula: C20H24N2O2. Mole weight: 324.42. | |
| Cotinine N-β-D-Glucuronide | Cotinine N-β-D-Glucuronide is a major metabolite of Nicotine in humans. Synonyms: 1-β-D-Glucopyranuronosyl-3-[(2S)-1-methyl-5-oxo-2-pyrrolidinyl]pyridinium Inner Salt; Cotinine-N-glucuronide. Grades: > 95%. CAS No. 139427-57-9. Molecular formula: C16H20N2O7. Mole weight: 352.34. | |
| Cotinine-N-b-glucuronide-D3 | Cotinine-N-b-glucuronide-D3 is a deuterated variant of Cotinine-N-b-glucuronide. Its utilization lies in the meticulous examination and identification of cotinine, an essential biomarker employed for assessing nicotine exposure. Being a metabolite generated through glucuronidation of cotinine in the liver, this compound greatly contributes to the scientific exploration of areas such as nicotine addiction, the cessation of smoking as well as the evaluation of outcomes pertaining to passive smoking. Molecular formula: C16H17N2O7D3. Mole weight: 355.36. | |
| COX-2-IN-1 | A potent and slective COX-2 inhibitor(IC50= 3.9 μM). Synonyms: 1-(4-Sulfamylphenyl)-3-trifluoromethyl-5-(7-chloroindol-3-yl)-2-pyrazoline; 4-[3-(7-chloro-1H-indol-3-yl)-5-(trifluoromethyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide. CAS No. 787623-48-7. Molecular formula: C18H14ClF3N4O2S. Mole weight: 442.84. | |
| COX-2-IN-2 | COX2-IN-1 is a selective and inducible COX2 inhibitor (IC50= 0.24 μM) with anti-inflammatory and analgesic activities. Synonyms: 1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrazole-3-carbonitrile. CAS No. 134729-13-8. Molecular formula: C17H12FN3O2S. Mole weight: 341.36. | |
| COX-2 Inhibitor I | An inhibitor of COX-2. Synonyms: Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate; LM-1685; LM 1685; LM1685. CAS No. 416901-58-1. Molecular formula: C18H16ClNO4S. Mole weight: 377.8. | |
| COX-2 Inhibitor II | A selective inhibitor of COX-2. Synonyms: SC-791; IN1371; 181696-33-3; 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide; SCHEMBL214781. CAS No. 181696-33-3. Molecular formula: C16H12F2N2O3S. Mole weight: 350.34. | |
| CP 115953 | CP 115953 is a Type II DNA topoisomerase inhibitor originated by Pfizer. CP 115953 inhibits topoisomerase II activity via an interaction with the enzyme and not by DNA unwinding. It can stimulate cytokine production by lymphocytes. Research for treatment of cancer was discontinued. Uses: Cancer. Synonyms: CP 115953; CP115953; CP-115953; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-3-quinolinecarboxylic acid. Grades: 98%. CAS No. 136440-70-5. Molecular formula: C19H13F2NO4. Mole weight: 357.31. | |
| CP-122721 | CP-122721, a phenylpiperidin derivative, has been found to be a NK1 receptor antagonist that could probably be effective as antidepressant and antiemetic agent. The result of Phase II clinical trial for depression of it has not been reported yet since 2003. Synonyms: CP122721; CP 122721; 3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-piperidine. Grades: 98%. CAS No. 145742-28-5. Molecular formula: C20H23F3N2O2. Mole weight: 380.40. | |
| CP 135807 | CP 135807, an indole derivative, has been found to be a selective 5-HT1D receptor agonist. Synonyms: CP135807; CP-135807; 3-(N-Methylpyrrolidin-2-ylmethyl)-5-(3-nitropyrid-2-ylamino)-1H-indole; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine. Grades: ≥98% by HPLC. CAS No. 151272-90-1. Molecular formula: C19H21N5O2. Mole weight: 351.40. | |
| CP22185 | CP22185 is a catecholamine-uptake inhibitor. Synonyms: CP-22185; CP 22185; Sertraline hydrochloride specified impurity B; (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine; N-Methyl-4alpha-phenyltetralin-1alpha-amine. Grades: 98%. CAS No. 52758-03-9. Molecular formula: C17H19N. Mole weight: 237.34. | |
| CP-466722 | CP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells. Synonyms: CP-466722; CP 466722; CP466722. Grades: >98%. CAS No. 1080622-86-1. Molecular formula: C17H15N7O2. Mole weight: 349.35. | |
| CP654577 | CP654577 is a selective p185(erbB2) kinase inhibitor. It could reduce the levels of the activated form of mitogen-activated protein kinase of SKBr3 human breast cancer cells. Synonyms: CP-654577; CP 654577; 3-Azabicyclo(3.1.0)hexane-6-methanol, 3-((4-(4-((3-methoxy-4-phenoxyphenyl)amino)-6-quinazolinyl)phenyl)methyl)-, (1alpha,5alpha,6alpha)-. Grades: 98%. CAS No. 639087-64-2. Molecular formula: C34H32N4O3. Mole weight: 544.65. | |
| CP-74667 mesylate | CP-74667 is a Type II DNA topoisomerase inhibitor originated by Pfizer. No development was reported for Bacterial infections in USA. Uses: Bacterial infections. Synonyms: CP-74667 mesylate; CP74667 mesylate; CP74667 mesylate; 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo(3.2.1)oct-3-yl)-4-oxo-3-Quinolinecarboxylic acid methanesulfonate (1:1);UNII-96Z3H79YX9. Grades: 98%. CAS No. 138808-71-6. Molecular formula: C21H26FN3O6S. Mole weight: 467.52. | |
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