BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Zaltoprofen | Zaltoprofen is an inhibitor of Cox-1 and Cox-2, and a nonsteroidal anti-inflammatory drug. Synonyms: 10,11-dihydro-alpha-methyl-10-oxodibenzo(b,f)thiepin-2-acetic acid; Zaltoprofen; CN 100; CN-100; CN100; WY-21743; WY 21743; WY21743. CAS No. 74711-43-6. Molecular formula: C17H14O3S. Mole weight: 298.36. |  |
| Zalunfiban | Zalunfiban is a new type of αIIbβ3 antagonist for prehospital treatment of myocardial infarction. Synonyms: RUC-4. Grades: >98%. CAS No. 1448313-27-6. Molecular formula: C16H18N8O2S. Mole weight: 386.4. | |
| Zalutumumab | Zalutumumab is a human IgG1 monoclonal antibody directed against EGFR. Zalutumumab binds to EGFR receptor and blocks receptor binding of EGF and TGF-a, inducing apoptosis of EGFR-expressing tumor cells. Synonyms: HuMax-EGFR. CAS No. 667901-13-5. | |
| Zegocractin | Zegocractin is a selective Orai1 inhibitor that prevents Ca2+ entry in acinar cells. Synonyms: CM-4620; CM 4620; CM4620. Grades: >98%. CAS No. 1713240-67-5. Molecular formula: C19H11ClF3N3O3. Mole weight: 421.76. | |
| Zilovertamab | Zilovertamab is a first-in-class humanized monoclonal antibody that binds to ROR1. Zilovertamab has been undergoing clinical trials in combination with ibrutinib for the treatment of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL). Synonyms: cirmtuzumab; UC-961. CAS No. 2485779-13-1. | |
| ZINC00881524 | ZINC00881524 is a specific ROCK inhibitor. Synonyms: ZINC00881524; ZINC-00881524; ZINC 00881524. N-(4,5-dihydrobenzo[e][1,3]benzothiazol-2-yl)-2-(3,4-dimethoxyphenyl)acetamide. Grades: >98%. CAS No. 557782-81-7. Molecular formula: C21H20N2O3S. Mole weight: 380.46. | |
| ZINC12613047 | ZINC12613047 is a selective butyrylcholinesterase (BChE) inhibitor with IC50 value of 21 nM and 102.1 μM for human and mouse BChE, respectively. Synonyms: N-[[1-(2,3-dihydro-1H-inden-2-yl)piperidin-3-yl]methyl]-N-(2-methoxyethyl)naphthalene-2-carboxamide. Grades: ≥95%. CAS No. 1069521-64-7. Molecular formula: C29H34N2O2. Mole weight: 442.6. | |
| Zinc glucoheptonate | Zinc glucoheptonate is an indispensable biomedical formulation, serving as a tool to study zinc insufficiencies prevailing within the biological system. Synonyms: Zinc, bis(D-glycero-D-ido-heptonato)-; 68475-48-9; 12565-63-8; Zinc diheptonate; Bis(D-glycero-D-ido-heptonato)zinc; D-Glycero-D-ido-Heptonic acid, zinc salt (2:1); EINECS 270-646-8; SCHEMBL20680077; DTXSID20925201. CAS No. 12565-63-8. Molecular formula: C14H26O16Zn. Mole weight: 515.73. | |
| ZK-Thiazolidinone | ZK-Thiazolidinone, also known as TAL, is an ATP-competitive inhibitor of PLK1. In vitro, ZK-Thiazolidinone counteracts the role of Plk1 in previously established functions, notably, sister chromatid separation, centrosome maturation, and bipolar spindle assembly. Synonyms: TAL. Grades: 98%. CAS No. 891849-87-9. Molecular formula: C23H30F3N5O2S. Mole weight: 497.58. | |
| ZM 39923 HCl | ZM 39923 HCl is a potent and selective inhibitor of JAK3, and also inhibits EGFR, JAK1 and CDK4. It breaks down in neutral buffer (t½ = 36 mins, pH 7.43, 25°C) to form ZM 449829. Synonyms: ZM 39923 hydrochloride; JAK3 Inhibitor IV; 3-[benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride. Grades: >98%. CAS No. 1021868-92-7. Molecular formula: C23H25NO.HCl. Mole weight: 367.91. | |
| Zolbetuximab | Zolbetuximab is a monoclonal antibody that targets CLDN18.2, a biomarker of gastric and gastroesophageal junction (GEJ) adenocarcinoma. Zolbetuximab mediates tumor cell death via antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Synonyms: IMAB362. CAS No. 1496553-00-4. | |
| Zoledronic Acid | Zoledronic acid induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. Synonyms: Zoledronate, CGP-4244; CGP 4244; CGP4244. Grades: >98%. CAS No. 118072-93-8. Molecular formula: C5H10N2O7P2. Mole weight: 272.09. | |
| Zomepirac-acyl-beta-D-Glucuronide | One of the Glucuronide-derived impurities of Zomepirac, which could be used as an anti-inflammatory as well as analgesic agent. Synonyms: 1-[5-(4-Chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetate] β-D-Glucopyranuronic Acid; Zomepirac Glucuronide; Zomepirac Acyl-1-O-β-D-glucuronide. CAS No. 75871-31-7. Molecular formula: C21H22ClNO9. Mole weight: 467.85. | |
| Zoniporide | Zoniporide, also called as CP-597,396, is a potent and selective Na(+)/H(+) exchanger (NHE) with high aqueous solubility and acceptable pharmacokinetics for intravenous administration. Zoniporide displays selectivity over other NHE isoforms (Ki values are 14, 2200 and 220000 nM for human NHE1, human NHE2 and rat NHE3 respectively). Synonyms: N-Carbamimidoyl-5-cyclopropyl-1-(quinolin-5-yl)-1H-pyrazole-4-carboxamide; N-(5-Cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine. Grades: >98%. CAS No. 241800-98-6. Molecular formula: C17H16N6O. Mole weight: 320.35. | |
| Zorubicin | Zorubicin is a benzoyl-hydrazone derivative of the anthracycline antineoplastic antibiotic daunorubicin. Zorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Synonyms: RP-22050; RP 22050; RP22050; Zorubicine; N'- (1-{ (2S, 4S) -4-[ (3-Amino-2, 3, 6-trideoxy-α -L-lyxo-hexopyranosyl) oxy]-2, 5, 12-trihydroxy-7-methoxy-6, 11-dioxo-1, 2, 3, 4, 6, 11-hexahydro-2-tetracenyl}ethylidene) benzohydrazide; Rubidazone; Benzoic acid hydrazide, 3-hydrazone with daunorubicin; Benzoic acid, (1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide, (2S-cis)-; Benzoic acid, 2-[1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide; Daunomycin benzoylhydrazone; MCMC 4222; Rubidazon. Grades: ≥95%. CAS No. 54083-22-6. Molecular formula: C34H35N3O10. Mole weight: 645.66. | |
| ZP 1609 | ZP 1609, a small modified dipeptide, has been identified as a potent and selective second generation gap junction modifier with oral bioavailability. It is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy, which is confirmed in phase I clinical trials. It is used for the treatment of atrial fibrillation. It improves conduction and reduces atrial fibrillation or flutter in the canine sterile pericarditis model. It prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs. It showed consistent efficacy on measures of conduction and AF/AFL inducibility in the canine sterile pericarditis model. It was developed by Zealand Pharma and was termination in Clinical phase II. Uses: Zp 1609 is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy. it is used for the treatment of atrial fibrillation. Synonyms: GAP-134; GAP 134; GAP134; ZP-1609; ZP1609; ZP 1609; (2S,4R)-1-(2-aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic acid;Danegaptide. Grades: >98 %. CAS No. 943134-39-2. Molecular formula: C14H17N3O4. Mole weight: 291.30. | |
| ZP 1609 Hydrochloride | ZP 1609 Hydrochloride is the hydrochloride form of ZP 1609, which is a small modified dipeptide and has been identified as a potent and selective second generation gap junction modifier with oral bioavailability. It is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy, which is confirmed in phase I clinical trials. It is used for the treatment of atrial fibrillation. It was developed by Zealand Pharma and was termination in Clinical phase II. Uses: Zp 1609 hydrochloride is a pharmalogical agent with a favorable clinical safety profile and potential antiarrhythmic efficacy. it is used for the treatment of atrial fibrillation. Synonyms: Danegaptide Hydrochloride;GAP 134 Hydrochloride;(4R)-Glycyl-4-(benzoylamino)-L-proline hydrochloride (1:1);ZP-1609 Hydrochloride; ZP 1609 Hydrochloride; ZP1609 Hydrochloride; (2S,4R)-1-(2-Aminoacetyl)-4-benzamidopyrrolidine-2-carboxylic Acid Hydrochloride. Grades: >98 %. CAS No. 943133-81-1. Molecular formula: C14H18ClN3O4. Mole weight: 327.76. | |
| ZP-4982 | ZP-4982 is a long-acting analog of amylin. It exhibited a hpyerglycemic effect in preclinical research, which demonstrated that it was promisingly used as an antidiabetic agent. Uses: The potential treatment of diabetes. Synonyms: ZP 4982; ZP4982. | |
| ZP-5461 | ZP-5461 is a long-acting analog of amylin. It exhibited a hpyerglycemic effect in preclinical research, which demonstrated that it was promisingly used as an antidiabetic agent. Uses: The potential treatment of diabetes. Synonyms: ZP 5461; ZP5461. | |
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