BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| TS-3112 | TS-3112 is an aminoglycoside antibiotic modified from apramycin derivative, which exhibits a conspicuous activity for resistant bacteria. Uses: Aminoglycoside antibiotic used for resistant bacteria. Synonyms: TS 3112; TS3112. |  |
| TTP 22 | Potent and ATP-competitive casein kinase 2 (CK2) inhibitor (IC50 = 0.1 μM, Ki=40 nM). Synonyms: TTP22; TTP-22. Grades: >98%. CAS No. 329907-28-0. Molecular formula: C16H14N2O2S2. Mole weight: 330.42. | |
| TTT-3002 | TTT-3002 is a tyrosine kinase inhibitor (TKI) that is one of the most potent FLT3 inhibitors discovered to date. TTT-3002 showed potent activity when tested against the most frequently occurring FLT3-activating point mutation, FLT3/D835Y, against which many current TKIs are ineffective. Survival and tumor burden of mice in several FLT3/ITD transplantation models is significantly improved by administration of TTT-3002 via oral dosing. TTT-3002 has demonstrated preclinical potential as a promising new FLT3 TKI in the treatment of FLT3-mutant AML. Synonyms: TTT 3002; TTT3002. Grades: 98%. CAS No. 871037-95-5. Molecular formula: C27H23N5O3. Mole weight: 465.51. | |
| Tubacin | Tubacin was used to study the role of HDAC6 in migration and invasion of bladder cancer cells. Tubacin (tubulin acetylation inducer) is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM. Uses: Histone deacetylase inhibitors. Synonyms: rel-N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide; Octanediamide, N1-(4-((2R,4R,6S)-4-(((4,5-diphenyl-2-oxazolyl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxy-, rel-. Grades: ≥95%. CAS No. 537049-40-4. Molecular formula: C41H43N3O7S. Mole weight: 721.86. | |
| Turicine | Turicine, an all-natural anti-inflammatory and anti-tumor agent, is a promising biomedicine. Its power lies in its ability to interrupt the growth of malignant cells and reduce painful inflammation in ailments such as arthritis. Through its ability to regulate key signaling pathways, Turicine shows great potential as a therapeutic agent. However, further research is needed to unlock the full scope of its healing capabilities. Synonyms: (2R,4R)-4-Hydroxy-1-dimethylpyrrolidine-2-carboxylate; (2R,4R)-2-Carboxy-4-hydroxy-1,1-dimethylpyrrolidin-1-ium; (+)-Turicine; cis-4-hydroxy-D-proline betaine; cis-hydroxyproline betaine; (2R-Cis)-2-carboxy-4-hydroxy-1,1-dimethylpyrrolidinium inner salt; Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, inner salt, (2R,4R)-; Stachydrine. Grades: ≥95%. CAS No. 515-24-2. Molecular formula: C7H13NO3. Mole weight: 159.18. | |
| Tusamitamab | Tusamitamab is a monoclonal antibody targeting CEACAM5. Tusamitamab can be used in the synthesis of tusamitamab ravtansine, an ADC with potential antineoplastic activity. CAS No. 2349294-95-5. | |
| TWS119 | TWS119 is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway. Synonyms: NSC 405020; NSC405020; NSC-405020; 3-((6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenol; TWS-119; TWS119; TWS 119. Grades: >98%. CAS No. 601514-19-6. Molecular formula: C18H14N4O2. Mole weight: 318.336. | |
| TWS 119 Trifluoroacetate | TWS 119 is a glycogen synthase kinase-3β (GSK-3) inhibitor (IC50 = 30 nM). TWS 119 induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESCs). Synonyms: TWS 119; TWS119; TWS-119; 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxyphenol ditrifluoroacetate. Grades: ≥98% by HPLC. CAS No. 1507095-58-0. Molecular formula: C18H14N4O2.2CF3CO2H. Mole weight: 546.38. | |
| TY-52156 | TY-52156 is a potent and selective sphingosine-1-phosphate receptor 3 (S1P3) antagonist in a competitive manner with Ki value of 110 nM. It inhibits S1P-induced breast cancer stem cell expansion in vitro. Uses: Ty-52156 can inhibit breast cancer stem cell expansion. it suppresses bradycardia. Synonyms: TY 52156; N-(4-chloroanilino)-N'-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidamide. Grades: >98%. CAS No. 934369-14-9. Molecular formula: C18H19Cl2N3O. Mole weight: 364.27. | |
| Tyrosol Glucuronide | Tyrosol Glucuronide is a derivative of tyrosol, which is phenolic antioxidant. Synonyms: 4-(2-Hydroxyethyl)phenyl β-D-Glucopyranosiduronic Acid. Grades: 97%. CAS No. 28116-28-1. Molecular formula: C14H18O8. Mole weight: 314.29. | |
| Tyrphostin AG 1296 | Tyrphostin AG 1296 is an inhibitor of PDGFR with an IC50 of 0.3-0.5 μM, no activity to EGFR. It inhibits FGFR and C-Kit with IC50s of 12.3 and 1.8 μM in Swiss 3T3 cells, respectively. Tyrphostin AG 1296 induces intense apoptosis in A375R cells. Synonyms: AG 1296; AG1296; AG-1296; 2-Phenyl-6,7-dimethoxyquinoxaline. Grades: >98%. CAS No. 146535-11-7. Molecular formula: C16H14N2O2. Mole weight: 266.29. | |
| TZ9 | TZ9, a triazine compound, is a new inhibitor of human E2 enzyme which could selectively bind to the Rad6B catalytic site to restrain the ubiquitination of substrate that was related to Rad6B. It could inhibit MDA-MB-231 cell proliferation with IC50 of 6μm. Uses: Tz9, a triazine compound, is a new inhibitor of human e2 enzyme which could selectively bind to the rad6b catalytic site to restrain the ubiquitination of substrate that was related to rad6b. Synonyms: TZ9; TZ 9; TZ-9; CS-3536; CS 3536; CS3536; B4861; B 4861; B-4861. Grades: 98%. CAS No. 1002789-86-7. Molecular formula: C17H14N6O4. Mole weight: 366.33. | |
| U0126 | U0126 is a MAPK inhibitor with antitumor activity. It inhibits MEK1 and MEK2 with IC50 values of 72 nM and 58 nM, respectively. U0126 inhibits tumorigenicity of liver cancer stem cells. Uses: Enzyme inhibitors. Synonyms: U-0126; U 0126; 1,4-Diamino-2,3-dicyano-1,4-bis(o-aminophenylmercapto)butadiene. Grades: >98%. CAS No. 109511-58-2. Molecular formula: C18H16N6S2. Mole weight: 380.49. | |
| UA8967 | UA8967 is a membrane-active anti-tumor agent. Cytotoxicity studies in six pancreatic cancer cell lines, one normal human pancreatic ductal epithelial line and two colon cancer cells showed the IC50s UA8967 ranged from 12-61 μM for exposure times of 72 h. There was also no selective inhibition of DNA, RNA or protein synthesis after exposure to UA8967. UA8967 is observed to affect the plasma membrane. Synonyms: UA-8967; UA 8967; 3-[(4-Benzyl-1-piperazinyl)methyl]indole. CAS No. 17511-50-1. Molecular formula: C20H23N3. Mole weight: 305.42. | |
| Ubiquitin Isopeptidase Inhibitor I, G5 | Ubiquitin Isopeptidase Inhibitor I, G5, a cell-permeable cross-conjugated unsaturated dienone compound, is an apoptosome-independent caspase and apoptosis activator with IC50 values of 1.76 and 1.6 μM in E1A and E1A/C9DN cells, respectively. Synonyms: NSC-144303; NSC144303; NSC 144303; G5. 3,5-bis[(4-nitrophenyl)methylidene]-1,1-dioxothian-4-one. CAS No. 108477-18-5. Molecular formula: C19H14N2O7S. Mole weight: 414.39. | |
| Ubrogepant | Ubrogepant is and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist originated by Merck & Co. In Sep 2016, Allergan initiated a phase III extension trial for Migraine in USA. Uses: Migraine. Synonyms: MK-1602; MK 1602; MK1602; Ubrogepant; (3'S)-1',2',5,7-Tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)-3-piperidinyl]-2'-oxo-spiro[6H-cyclopenta[b]pyridine-6,3'-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide. Grades: 98%. CAS No. 1374248-77-7. Molecular formula: C29H26F3N5O3. Mole weight: 549.55. | |
| UCLA GP130 2 | UCLA GP130 2 is a brain-penetrant gp130 agonist, protecting against NMDA-induced toxicity in primary hippocampal neurons in vitro, and increasing STAT3 phosphorylation in SH-SY5Y cells. Synonyms: N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine. Grades: ≥98% by HPLC. CAS No. 339303-87-6. Molecular formula: C15H11FN2S. Mole weight: 270.32. | |
| UD-014 | UD-014 is a selective and long-acting inhibitor of semicarbazide-sensitive amine oxidase (SSAO; VAP-1) (IC50 = 3.2 nM), which shows a therapeutic effect of diabetic nephropathy in a streptozotocin rat model. Uses: The treatment of diabetic nephropathy. Synonyms: UD 014; UD014. | |
| UDP-2-deoxy-2-fluoro-D-galactose | UDP-2-deoxy-2-fluoro-D-galactose is a valuable tool in the biomedical industry known for its ability to mimic natural carbohydrates. It can be utilized to investigate the potential therapeutic applications and drug design targeting specific diseases related to carbohydrate metabolism. Synonyms: UDP-2FGal; Uridine 5-(trihydrogen diphosphate), P-(2-deoxy-2-fluoro-α-D-galactopyranosyl) ester. CAS No. 118694-15-8. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29. | |
| UDP-2-deoxy-2-fluoro-D-glucose | UDP-2-deoxy-2-fluoro-D-glucose is an indispensable compound, serving as a potent tool in positron emission tomography (PET) imaging. By virtue of its radiochemical attributes, this glucose analog enables the non-intrusive observation of in vivo glucose metabolism. Its application extends to the research of multifarious conditions encompassing cancer, neurodegenerative ailments and infectious pathologies. Synonyms: Uridine-2-deoxy-2-fluoro-D-glucose diphosphate ester. CAS No. 67341-43-9. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29. | |
| UDP-2-deoxy-2-fluoro-D-mannose | UDP-2-deoxy-2-fluoro-D-mannose is an antiviral compound in the dynamic biomedical sector used for studying diverse viral infections, notably influenza. Synonyms: Uridine 5-(trihydrogen diphosphate), P-(2-deoxy-2-fluoro-a-D-mannopyranosyl) ester. CAS No. 67341-44-0. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29. | |
| UDP-2-ketopropyl-a-D-galactose | | |
| UDP-(3-O-(R-3-hydroxydecanoyl)) N-acetylglucosamine | UDP-(3-O-(R-3-hydroxydecanoyl)) N-acetylglucosamine is an indispensable compound, assuming a critical function in the synthetic pathway of lipid A, a fundamental constituent of bacterial lipopolysaccharides. Its application within the realm of microbial pathogenesis research is extensive, particularly in elucidating the intricate mechanisms underlying lipopolysaccharide biosynthesis and in identifying prospective drug targets to confront pernicious bacterial infections. Synonyms: Uridine-5'-Diphosphate-3-O-(R-3-Hydroxydecanoyl)-N-Acetyl-D-Glucosamine; (3R)- (2R, 3R, 4R, 5S, 6R)-3-Acetamido-2- ( ( ( ( ( ( (2R, 3S, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-3, 4-dihydroxytetrahydrofuran-2-yl)methoxy) (hydroxy)phosphoryl)oxy) (hydroxy)phosphoryl)oxy)-5-hydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-4-yl 3-hydroxydecanoate; [(2R,3R,4R,5S,6R)-3-acetamido-2-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl] (3R)-3-hydroxydecanoate; 953426-26-1; U21; Q27466807; (2R, 3R, 4R, 5S, 6R)-3- (acetylamino)-2-{[ (R)-{[ (S)-{[ (2R, 3S, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-3, 4-dihydroxytetrahydrofuran-2-yl]methoxy} (hydroxy)phosphoryl]oxy} (hydroxy)phosphoryl]oxy}-5-hydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-4-yl (3R)-3-hydroxydecanoate (non-preferred name). CAS No. 953426-26-1. Molecular formula: C27H45N3O19P2. Mole weight: 777.60. | |
| UDP-3-O-(R-3-hydroxymyristoyl)-N-acetyl-D-glucosamine | UDP-3-O-(R-3-hydroxymyristoyl)-N-acetyl-D-glucosamine is a fundamental substrate widely utilized in the sweeping realm of biomedical science, holding application in the intricate synthesis of lipid A, which is the cardinal constituent that underpins the remarkable lipopolysaccharide (LPS) architecture within bacteria of the Gram-negative ilk. Molecular formula: C31H53N3O19P2. Mole weight: 833.71. | |
| UDP-4-azido-4-deoxy-D-glucose | Cas No. 1030832-12-2. | |
| UDP-6-azido-6-deoxy-D-galactose | UDP-6-azido-6-deoxy-D-galactose is a paramount resource within the biomedical sector for the research of glycosylation investigations, acting as a precursor substance for the creative fabrication of manifold galactose-imbued substances. Its idiosyncratic azide moiety engenders its utility for nutrient labeling metabolic assays, the revolutionary click chemistry methodology and profound bioorthogonal reactions. This diversified compound showcases extensive applicability towards the research of galactose-selective interactions, the fostering of glycoconjugate pioneering endeavors and the insightful exploration of carbohydrate-mediated physiological phenomena. CAS No. 868141-12-2. Molecular formula: C15H21N5O16P2 2(C6H16N). Mole weight: 793.69. | |
| UDP-6-azido-6-deoxy-D-glucose | UDP-6-azido-6-deoxy-D-glucose is a vital compound used in biomedical field as a metabolic precursor for glycobiology research. It is commonly utilized in the synthesis of azidosugars, which are crucial for investigating glycoconjugates and understanding their roles in diseases like cancer and viral infections. Synonyms: [6-(Azidomethyl)-3,4,5-trihydroxyoxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate; uridine 5'-(trihydrogn diphosphate), P'-(6-azido-6-deoxy-?-D-glucopyranosyl) ester. CAS No. 537039-67-1. Molecular formula: C15H21N5O17P2. Mole weight: 605.30. | |
| UDP-a-D-apiofuranose | | |
| UDP-a-D-xylose | UDP-a-D-xylose is an indispensable resource, finding extensive application in investigating the intricate involvement of nucleotide sugars in an assortment of cellular mechanisms. With role as a fundamental substrate for enzymatic processes governing the synthesis of glycoproteins, glycolipids and proteoglycans, this esteemed product holds applications in studying maladies associated with aberrant glycosylation, including congenital disorders of glycosylation and select cancer types. Synonyms: uridine[5]diphospho-a-D-xylopyranoside. Molecular formula: C14H22N2O16P2. Mole weight: 536.28. | |
| UDP-a-L-rhamnose | UDP-α-L-rhamnose is a vital biomolecule prevalent in the biomedical sector, holding a noteworthy function in the biosynthesis of glycolipids, polysaccharides and natural products. Displaying its extraordinary aptitude as a sugar donor, this compound becomes indispensable in the enzymatic process of synthesizing multifaceted carbohydrates. Notably, UDP-α-L-rhamnose acts as a precursor for generating glycoconjugates containing rhamnose, used to study infectious ailments. Synonyms: Uridine 5-[3-(6-deoxy-L-mannopyranosyl) dihydrogen diphosphate]; Uridine 5-[3-(L-rhamnopyranosyl) dihydrogen diphosphate]. CAS No. 30174-43-7. Molecular formula: C15H24N2O16P2. Mole weight: 550.30. | |
| UDP-apiose | UDP-apiose is an indispensable biochemical compound, aiding in studying a diverse array of afflictions such as malignant neoplasms, inflammatory cascades and prodigious autoimmune maladies. By serving as a foundational blueprint for the research of apiosyl enzymes and glycoproteins, it assumes a pivotal stance in orchestrating vital pathways of cellular communication. Synonyms: Uridine diphospho-D-apiose. CAS No. 36020-60-7. Molecular formula: C14H22N2O16P2. Mole weight: 536.28. | |
| UDP-b-L-arabinose | UDP-b-L-arabinose is an indispensable compound, serving as a pivotal substratum in the intricate process of glycoprotein, glycolipid and proteoglycan biosynthesis. Its overarching role encompasses studying cancer, infectious diseases and autoimmune disorders. Synonyms: uridine[5]diphospho-b-L-arabinopyranoside. CAS No. 15839-78-8. Molecular formula: C14H22N2O16P2. Mole weight: 536.28. | |
| UDP-b-L-fucose diammonium salt | UDP-b-L-fucose diammonium salt is a vital compound extensively used in the biomedical industry. It serves as a precursor for the synthesis of fucosylated biomolecules, such as glycans and glycoproteins. Its exceptional properties is used in studying various drug targets and disease pathways associated with fucosylation. Molecular formula: C15H22N2O16P2 N2H8. Mole weight: 584.37. | |
| UDP-D-galactosamine disodium salt | UDP-D-galactosamine disodium salt is an indispensable compound extensively employed in the realm of in the orchestration of glycosaminoglycans' biosynthesis, thereby significantly influencing the processes of cellular communication, immune response and the architecture of the extracellular matrix. Synonyms: Udp galactosamine; UDP-galactosamine; Uridine diphosphate galactosamine; UDP-alpha-D-galactosamine; 17479-06-0; CHEBI:16846; Uridine 5'-diphosphogalactosamine; [(2R,3R,4R,5R,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate; AC1Q6SAB; UDPgalactosamine; UDP-GalN; Uracil Diphosphate galactosamine; CHEMBL2092918; CYKLRRKFBPBYEI-KBQKSTHMSA-N; DTXSID901316536; C02467; Q27102108; uridine 5'-[3-(2-amino-2-deoxygalactopyranosyl) dihydrogen diphosphate]; [(2R,3R,4R,5R,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] hydrogen phosphate. CAS No. 17479-06-0. Molecular formula: C15H23N3O16P2Na2. Mole weight: 609.28. | |
| UDP-D-galactose disodium salt | UDP-D-galactose disodium salt is a vital biomolecule used in the biomedical industry for its role as a substrate in glycosylation reactions. It is primarily utilized in the synthesis of glycans, glycoproteins and glycolipids involved in various cellular processes. This disodium salt form facilitates precise and controlled glycosylation aiding in the research of diseases related to aberrant glycosylation, such as certain cancers and genetic disorders. Molecular formula: C15H22N2O17P2 2Na. Mole weight: 610.27. | |
| UDP-D-glucose disodium salt - Approx 30% content by UV | UDP-D-glucose disodium salt is a highly significant biochemical instrument extensively employed within the biomedical sector, serving as an eminent substrate for countless enzymes intricately entwined in the metabolism of glucose. Embodying an approximate 30% proportion, this compound fundamentally contributes to the intricate synthesis of glycogen, cellulose and various other carbohydrates. Molecular formula: C15H22N2Na2O17P2. Mole weight: 610.27. | |
| UDP-L-galactose diammonium salt | UDP-L-galactose diammonium salt is a crucial biochemical compound used in the biomedical industry for the synthesis of carbohydrates. It acts as a donor substrate in various enzymatic reactions, including glycosyltransferases, contributing to the biosynthesis of glycoproteins. This product plays a significant role in the research of diseases associated with aberrant glycosylation patterns, such as certain cancers and congenital disorders. Molecular formula: C15H22N2O17P2 N2H8. Mole weight: 600.37. | |
| UDP-N-acetyl-D-glucosamine disodium salt | UDP-N-acetyl-D-glucosamine disodium salt is a crucial biochemical used in the biomedical industry for the synthesis of glycosaminoglycans, antibiotics and antifungal compounds. It plays a vital role in studying bacterial and fungal infections, as well as assisting in the production of certain drugs targeting diseases like cancer and arthritis. Synonyms: UDP GlcNAc. CAS No. 91183-98-1. Molecular formula: C17H25N3O17P2Na2. Mole weight: 651.32. | |
| UDP-N-acetyl-D-mannosamine | UDP-N-acetyl-D-mannosamine is a key compound in the biomedical sector, exhibiting indispensability in synthesizing sialic acids, which carry out pivotal functions across diverse biological phenomena. with application in glycoprotein, glycolipid and essential molecule production, it assumes a critical role in cellular communication, immune response modulation and neurobiological processes. Furthermore, its utilization extends to disease research and investigative endeavors regarding cancer, viral infections and genetic anomalies. Synonyms: UDP-ManNAc; UDP-N-acetyl-alpha-D-mannosamine; UDP-N-Acetylmannosamine; UDP-acetylmannosamine; UDP-N-acetyl-D-mannosamine; 26575-17-7; uridine diphosphate N-acetylmannosamine; uridine 5'-[3-(2-acetamido-2-deoxy-alpha-D-mannopyranosyl) dihydrogen diphosphate]; (2R,3S,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen diphosphate (non-preferred name); CHEBI:68678; LFTYTUAZOPRMMI-ZYQOOJPVSA-N; DTXSID701313724; UD1; [(2R,3S,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl] [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate; C01170; Q27137103; UD9. CAS No. 26575-17-7. Molecular formula: C17H27N3O17P2. Mole weight: 607.35. | |
| UDP-N-acetyl-D-mannosaminuronic acid | Synonyms: Udp-N-acetyl-D-mannosaminuronic acid; UDP-N-acetyl-alpha-D-mannosaminouronic acid; UDP-N-acetyl-2-amino-2-deoxy-D-mannuronate; uridine 5'-[3-(2-acetamido-2-deoxy-alpha-D-mannopyranosyluronic acid) dihydrogen diphosphate]; (2s,3s,4r,5s,6r)-5-Acetamido-6-[[[(2r,3s,4r,5r)-5-[2,4-Bis(Oxidanylidene)pyrimidin-1-Yl]-3,4-Bis(Oxidanyl)oxolan-2-Yl]methoxy-Oxidanyl-Phosphoryl]oxy-Oxidanyl-Phosphoryl]oxy-3,4-Bis(Oxidanyl)oxane-2-Carboxylic Acid; UDP-N-acetyl-alpha-D-mannosaminuronate; C06240; CHEBI:70738; (2S,3S,4R,5S,6R)-5-acetamido-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4-dihydroxyoxane-2-carboxylic acid; J-700273; Q27139053; (2S, 3S, 4R, 5S, 6R)-5- (acetylamino)-6-{[ (R)-{[ (R)-{[ (2R, 3S, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-3, 4-dihydroxytetrahydrofuran-2-yl]methoxy} (hydroxy)phosphoryl]oxy} (hydroxy)phosphoryl]oxy}-3, 4-dihydroxytetrahydro-2H-pyran-2-carboxylic acid (non-preferred name); SAJ. Molecular formula: C17H25N3O18P2. Mole weight: 621.3. | |
| UK 39671 | UK 39671 is a cytochrome P-450 inhibitor. Synonyms: UK 39671; UK39671; UK-39671; 2-(2,4-dichlorophenyl)-1-(1H-imidazol-1-yl)octan-2-ol. Grades: 98%. CAS No. 85473-17-2. Molecular formula: C17H22Cl2N2O. Mole weight: 341.28. | |
| Ukrain | Ukrain is an anticancer drug based on the extract of the plant Chelidonium majus L. Numerous pre-clinical and clinical investigations seem to suggest that Ukrain is pharmacologically active and clinically effective. Ernst E, Schmidt K critically evaluate d the clinical trial data in the form of a systematic review. The data from randomised clinical trials suggest Ukrain to have potential as an anticancer drug. However, numerous caveats prevent a positive conclusion, and independent rigorous studies are urgently needed. Uses: Adjuvants, immunologic. Synonyms: NSC 631570; NSC631570; NSC-631570; Ukrain. CAS No. 138069-52-0. Molecular formula: C66H75N6O18PS. Mole weight: 1303.38. | |
| Uliledlimab | Uliledlimab is a humanized anti-CD73 monoclonal antibody with antineoplastic activity. Uliledlimab inhibits adenosine generation in a non-competitive manner and suppresses tumor growth when combined with a PD-L1 inhibitor. Synonyms: TJ004309. CAS No. 2378407-27-1. | |
| Ulodesine | Ulodesine, also known as BCX4208, is a purine nucleoside phosphorylase (PNP) inhibitor in development as a once-daily oral, chronic treatment for gout. Ulodesine is currently being developed by Biocryst. Ulodesine acts upstream of xanthine oxidase in the purine metabolism pathway to reduce the production of serum uric acid (sUA). Ulodesine has an IC(50) of 0.5 nM to PNP. BCX-4208 is currently undergoing early clinical investigation in psoriasis and gout. (last update: ). Synonyms: BCX4208; BCX 4208; BCX-4208; DADMe-immucillin H. CAS No. 548486-59-5. Molecular formula: C12H16N4O3. Mole weight: 264.28. | |
| UNBS3157 | UNBS3157 is a DNA intercalator, and a novel nonhematotoxic naphthalimide derivative with potent antitumor activity. Amonafide, a naphthalimide which binds to DNA by intercalation and poisons topoisomerase IIalpha, has demonstrated activity in phase II breast cancer trials, but has failed thus far to enter clinical phase III because of dose-limiting bone marrow toxicity. Synonyms: UNBS 3157; UNBS-3157. Grades: 98%. CAS No. 868962-26-9. Molecular formula: C19H17Cl3N4O4. Mole weight: 471.72. | |
| UNC569 | Mer proto-oncogene tyrosine kinase (MerTK) is expressed in the retinal pigment epithelium (RPE), regulates phagocytosis of shed photoreceptor outer segments (POS). UNC569 is a specific MerTK inhibitor. Synonyms: 1-[(Trans-4-Aminocyclohexyl)methyl]-N-Butyl-3-(4-Fluorophenyl)-1h-Pyrazolo[3,4-D]pyrimidin-6-Amine. Grades: 98%. CAS No. 1350547-65-7. Molecular formula: C22H29FN6. Mole weight: 396.50. | |
| Upifitamab | Upifitamab is a naked antibody of upifitamab rilsodotin, an ADC targeting the sodium-dependent phosphate transport protein NaPi2b expressed on tumor cells. CAS No. 2254118-43-7. | |
| Urabrelimab | Urabrelimab is a humanized anti-CD47 monoclonal antibody. Urabrelimab binds to CD47 and inhibits CD47-SIRPα interaction. Urabrelimab exerts antitumor activity in vitro through both phagocytosis and cell death in a manner dependent on the activating Fc-gamma receptor (FcγR), CD32a. Synonyms: SRF-231; SRF231; SRF 231. CAS No. 2249722-58-3. | |
| Ursodeoxycholic acid acyl-b-D-glucuronide | Ursodeoxycholic acid acyl-b-D-glucuronide, an imperative compound in the field of biomedicine, serves as a remarkable treatment for cholestatic liver diseases. Derived from the esteemed ursodeoxycholic acid, it assumes the role of a hepatoprotective agent, substantially diminishing the build-up of pernicious bile acids within the hepatic system. Synonyms: URSODEOXYCHOLIC ACID ACYL-B-D-GLUCURONIDE; Ursodeoxycholic Acid Acyl-?-D-glucuronide, ~85%; (2S,3S,4S,5R,6S)-6-[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid; Ursodeoxycholic Acid Acyl-beta-D-glucuronide, >85per cent; W-201823. CAS No. 208038-28-2. Molecular formula: C30H48O10. Mole weight: 568.70. | |
| UT-155 | UT-155 is a potent and selective androgen receptor (AR) antagonist. UT-155 binds the amino-terminal transcriptional activation domain AF-1 and the carboxy-terminal ligand binding domain. Synonyms: UT155; UT 155. CAS No. 2031161-35-8. Molecular formula: C20H15F4N3O2. Mole weight: 405.35. | |
| Vacquinol-1 | Vacquinol-1, also known as NSC 13316, is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells. In glioblastoma cells, Vacquinol-1 targets macropinocytosis, a cellular process that will not lead to cell death in normal cells. Synonyms: Vacquinol 1; Vacquinol1; NSC 13316; NSC-13316; NSC13316. Grades: 98%. CAS No. 5428-80-8. Molecular formula: C21H21ClN2O. Mole weight: 352.86. | |
| Validamine | Validamine is a cutting-edge compound, serving as a tool of studying autoimmune diseases, most notably rheumatoid arthritis, owing to its inherent immunosuppressive properties. This compound successfully curbs the synthesis of inflammatory cytokines. Synonyms: 6-Amino-4-(hydroxymethyl)-4-cyclohexane-[4H,5H]-1,2,3-triol; (1R,2S,3S,4S,6R)-4-Amino-6-(hydroxymethyl)cyclohexane-1,2,3-triol. CAS No. 32780-32-8. Molecular formula: C7H15NO4. Mole weight: 177.2. | |
| Valienamine HCl | Valienamine HCl is a potent pharmaceutical compound used in the research of bacterial infections, particularly those caused by resistant strains. It exhibits antimicrobial activity by inhibiting the growth of bacteria. Valienamine HCl serves as a key ingredient in various antimicrobial drugs. Uses: Glycoside hydrolase inhibitors. Synonyms: (1S,2S,3R,6S)-6-Amino-4-(hydroxymethyl)-4-cyclohexene-1,2,3-triol. CAS No. 38231-86-6. Molecular formula: C7H13NO4. Mole weight: 175.18. | |
| Valiolamine | Valiolamine is an exceptional alkaloid compound, used for studying chronic myeloid leukemia (CML). By virtue of its extraordinary capability to impede tyrosine kinases, Valiolamine demonstrates unparalleled potency in studying leukemic manifestations. Synonyms: D-epi-Inositol, 4-amino-3,4-dideoxy-2-C-(hydroxymethyl)-; 4-Amino-3,4-dideoxy-2-C-(hydroxymethyl)-D-epi-inositol; EB 0155. Grades: ≥95%. CAS No. 83465-22-9. Molecular formula: C7H15NO5. Mole weight: 193.20. | |
| Valoneic Acid Dilactone | Valoneic Acid Dilactone is a polyphenol natural product. It shows an inhibitory effect on 5α-reductase. It also has selectively inhibited RNase L and shows antibacterial activity. Synonyms: Valoneic acid bilactone. Grades: 90% by HPLC. CAS No. 60202-70-2. Molecular formula: C21H10O13. Mole weight: 470.3. | |
| Valproic acid | Valproic acid is an inhibitor of histone deacetylase (HDAC) inhibitor, which has an anticancer effect. Valproic acid was shown to induce proliferation and enhance self-renewal of hematopoietic stem cells (HSC). Uses: Antimanic agents. Synonyms: VPA; 2-Propylpentanoic Acid. Grades: >98%. CAS No. 99-66-1. Molecular formula: C8H16O2. Mole weight: 144.21. | |
| Vanillic acid 4-β-D-glucoside | 4-(beta-D-glucopyranosyloxy)-3-methoxybenzoic acid is a tannin. It has a role as a metabolite. Synonyms: 3-methoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzoic acid; 4-Hydroxy-3-methoxybenzoic acid 4-|A-D-glucoside; Vanillic acid 4-|A-D-glucopyranoside; 4-(beta-D-Glucopyranosyloxy)-3-methoxybenzoic acid. Grades: ≥ 95%. CAS No. 32142-31-7. Molecular formula: C14H18O9. Mole weight: 330.29. | |
| Vanoxerine | Vanoxerine is a is a potent and selective DRI acts to block cardiac ion channels. Uses: Dat1 antagonist. Synonyms: 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine; GBR-12909; I-893. Grades: ≥98%. CAS No. 67469-69-6. Molecular formula: C28H32F2N2O. Mole weight: 450.56. | |
| Vanoxerine dihydroChloride | Vanoxerine is a is a potent and selective DRI acts to block cardiac ion channels. Uses: Dat1 antagonist. Synonyms: GBR 12909 Dihydrochloride; GBR12909 Dihydrochloride; GBR-12909 Dihydrochloride; 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine; dihydrochloride. Grades: ≥98%. CAS No. 67469-78-7. Molecular formula: C28H34Cl2F2N2O. Mole weight: 523.49. | |
| Varenicline carbamoyl glucuronide | Varenicline carbamoyl glucuronide is a metabolite of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: Varenicline carbamoyl beta-D-glucuronide; Varenicline Carbamoyl-ß-D-glucuronide; Tolcapone 3-ß-D-Glucuronide; 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate)β-D-Glucopyranuronic Acid; Metabolite M4. Grades: 98%. CAS No. 535920-98-0. Molecular formula: C20H21N3O8. Mole weight: 431.40. | |
| Varenicline N-glucoside | Varenicline N-glucoside is a metabolite of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: 8-b-D-Glucopyranosyl-7,8,9,10-tetrahydro-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine. Grades: > 98%. CAS No. 873302-31-9. Molecular formula: C19H23N3O5. Mole weight: 373.40. | |
| VEL-0230 | VEL-0230, also known as NC-2300, is a potent cathespin K inhibitor. VEL-0230 has dual-acting properties that both stimulates bone formation and inhibits loss. VEL-0230 is being studied preclinically for the treatment of diseases involving bone mineral disorders such as bone loss related to multiple myeloma, osteoporosis, bone metastases, and rheumatoid arthritis. Velcura Therapeutics is currently being developed by Velcura Therapeutics. Given VEL- 0230's promotion of bone formation, inhibition of bone loss and reduction of calcium levels, Velcura has chosen Myeloma as its lead indication, as the bone fragility, bone pain, high calcium levels and eventual kidney involvement present serious medical and quality of life issues to affected patients. Synonyms: VEL 0230; VEL0230; NC-2300; NC2300; NC 2300; sodium (2S,3S)-3-(((S)-1-isobutoxy-4-methylpentan-2-yl)carbamoyl)oxirane-2-carboxylate. CAS No. 221144-20-3. Molecular formula: C14H24NNaO5. Mole weight: 309.33. | |
| Veledimex racemate | Veledimex racemate is the racemate of veledimex. Veledimex is an orally active small molecule diacylhydrazine and controls the expression of the target gene. Synonyms: N'-(3,5-dimethylbenzoyl)-N'-(2,2-dimethylhexan-3-yl)-2-ethyl-3-methoxybenzohydrazide; Veledimex (racemate). CAS No. 755013-59-3. Molecular formula: C27H38N2O3. Mole weight: 438.6. | |
| Veledimex S enantiomer | Veledimex S enantiomer is the S enantiomer of veledimex which is an orally active small molecule diacylhydrazine and controls the expression of the target gene. Synonyms: N'-(3,5-dimethylbenzoyl)-N'-[(3S)-2,2-dimethylhexan-3-yl]-2-ethyl-3-methoxybenzohydrazide; Veledimex (S enantiomer). CAS No. 1093131-03-3. Molecular formula: C27H38N2O3. Mole weight: 438.6. | |
| Veltuzumab | Veltuzumab is a humanized anti-CD20 monoclonal antibody. Veltuzumab has been investigated for the treatment of non-Hodgkin's lymphoma. Synonyms: IMMU-106; hA20. CAS No. 728917-18-8. | |
| VER-250840 | VER-250840 is a novel oral Chk1 inhibitor (IC50 < 1 nM; Kd = 69 pM) with an antiproliferative activity against tumor cells. Uses: Potential antitumor drug. Synonyms: VER250840; VER 250840. | |
| Verofylline | Verofylline is used as a methylxanthine bronchodilator. Uses: Verofylline is used as a methylxanthine bronchodilator. Synonyms: CK 0383; CK0383; CK-0383; Verofilina; Verofyllinum; 3,7-Dihydro-1,8-dimethyl-3-(2-methylbutyl)-1H-purine-2,6-dione. Grades: 98%. CAS No. 66172-75-6. Molecular formula: C12H18N4O2. Mole weight: 250.30. | |
| Verubulin | Verubulin, also known as MPC-6827, is quinazoline derivative with potential dual antineoplastic activities. Verubulin hydrochloride binds to and inhibits tubulin polymerization and interrupts microtubule formation, resulting in disruption of mitotic spindle assembly, cell cycle arrest in the G2/M phase, and cell death. This agent is not a substrate for several subtypes of multidrug resistance ABC transporters, such as P-glycoprotein, multidrug resistance-associated protein 1 (MRP1), and breast cancer resistance protein 1 (BCRP1); therefore, it may be useful for treating multidrug resistant (MDR) tumors that express these transporters. In addition, as a vascular disrupting agent (VDA), MPC-6827 appears to disrupt tumor microvasculature specifically, which may result in acute ischemia and massive tumor cell death. Synonyms: MPC6827; MPC-6827; MPC 6827; MX128495; MX-128495; MX 128495; EP90745; EP-90745;EP 90745; Verubulin; trade name: Azixa. Grades: ≥98%. CAS No. 827031-83-4. Molecular formula: C21H25BrN3O9P. Mole weight: 279.34. | |
| Vestipitant | Cas No. 334476-64-1. | |
| Vibostolimab | Vibostolimab is an anti-TIGIT monoclonal antibody with antitumor activity. Vibostolimab has been investigated as a monotherapy for advanced solid tumors such as non-small-cell lung cancer (NSCLC). Synonyms: MK-7684; MK 7684; MK7684. CAS No. 2231305-30-7. | |
Our database is helping our users find suppliers everyday.
