BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tinostamustine Hydrochloride | The hydrochloride salt form of Tinostamustine, a benzimidazol derivative, has been found to be a HDAC inhibitor and could probably be effective against sorts of cancers like haematological malignancies and solid tumours. And it is still under Phase-I trial against solid tumours. Synonyms: EDO-S101; EDO-S 101; EDO-S-101; EDO-S101 HCl; EDO-S101 hydrochloride; Tinostamustine hydrochloride; 7-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)-N-hydroxyheptanamide hydrochloride. Grades: 98%. CAS No. 1793059-58-1. Molecular formula: C19H29Cl3N4O2. Mole weight: 451.82. |  |
| Tinurilimab | Tinurilimab is a humanized anti-CEACAM6 monoclonal antibody that binds to and blocks the activity of CEACAM6 expressed on various tumor and immune cells, including T cells. Synonyms: BAY 1834942; BAY-1834942; BAY1834942. CAS No. 2226224-30-0. | |
| Tioxolone | Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM. Synonyms: 6-Hydroxy-1,3-benzoxathiol-2-one. Grades: >98%. CAS No. 4991-65-5. Molecular formula: C7H4O3S. Mole weight: 168.17. | |
| Tipranovir b-D-glucuronide | Tipranovir b-D-glucuronide is a metabolite of the anti-HIV drug Tipranavir. It is a glucuronide conjugate that is formed in the liver and excreted in bile. This metabolite has no known pharmacological activity but can be used as a biomarker to monitor Tipranavir therapy. CAS No. 947408-14-2. Molecular formula: C37H41F3N2O11S. Mole weight: 778.79. | |
| Tiragolumab | Tiragolumab is a humanized monoclonal antibody and immune checkpoint inhibitor that selectively binds to TIGIT, which suppresses the immune response to cancer. Synonyms: anti-TIGIT; RG6058; MTIG7192A. CAS No. 1918185-84-8. | |
| Tizoxanide Glucuronide Sodium Salt | One of the metabolite impurities of Nitazoxanide, which is a hepatitis B as well as hepatitis C virus inhibitor and could exhibit potential effect in studies of tuberculosis. Synonyms: 2-[[(5-Nitro-2-thiazolyl)amino]carbonyl]phenyl β-D-Glucopyranosiduronic Acid Monosodium Salt. CAS No. 221287-83-8. Molecular formula: C16H14N3NaO10S. Mole weight: 463.35. | |
| TL-310 | TL310 is a novel, oral taxane with potent pre-clinical activity in taxane-resistant model systems. This is the first study to evaluate the safety, tolerability and pharmacokinetics (PK) of TL310 in pts with advanced refractory solid tumors. Synonyms: TL310; TL 310. CAS No. 352697-38-2. Molecular formula: C45H55NO16. Mole weight: 865.91. | |
| TLN-232 | TLN-232, also known as CAP-232, is a synthetic cyclic heptapeptide with potential antineoplastic activity. Pyruvate kinase (PK) inhibitor TLN-232 targets pyruvate kinase M2 (M2PK), which may disrupt tumor cell anaerobic glycolysis. M2PK is a dimeric isoform of PK and the predominant PK isoform found in tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Synonyms: TLN 232; TLN232; CAP-232; CAP 232; CAP232; H-D-Phe-Cys(1)-D-Trp-Lys-Cys(1)-Thr-NH2. CAS No. 158899-10-6. Molecular formula: C36H49N9O7S2. Mole weight: 783.96. | |
| TMCB | TMCB is a dual-kinase inhibitor of both casein kinase 2 (CK2) and extracellular-signal-regulated kinase 8 (ERK8) (IC50 = 0.50 μM for both CK2 and ERK8). TMCB exhibits selectivity for CK2 over protein kinases normally susceptible to CK2 inhibitors (Ki = 0.25, 8.65, 11.90 and 15.25 μM for CK2, PIM1, DYRK1a and HIPK2, respectively). Synonyms: 2-(4,5,6,7-Tetrabromo-2-(dimethylamino)-1H-benzo[d]imidazol-1-yl)acetic acid. Grades: ≥98% by HPLC. CAS No. 905105-89-7. Molecular formula: C11H9Br4N3O2. Mole weight: 534.82. | |
| TMI 1 | TMI 1 is a dual inhibitor of Adam 17 (TACE) and MMP inhibitor (IC50 = 3, 4.7, 6.6, 8.4, 12, 26 and 26 nM for MMP-13, MMP-2, MMP-1, ADAM 17, MMP-9, MMP-7 and MMP-14, respectively). TMI 1 suppresses TNF-α production in an acute LPS-mouse model. TMI 1 exhibits selective cytotoxicity to tumor cells and cancer stem cells in vitro, and induces apoptosis in a breast cancer in vivo model. Synonyms: TMI-1; TMI-1; TMI-1; (3S)-4-[[4-(2-Butyn-1-yloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-3-thiomorpholinecarboxamide. Grades: ≥98% by HPLC. CAS No. 287403-39-8. Molecular formula: C17H22N2O5S2. Mole weight: 398.49. | |
| TMS | TMS is a selective, competitive inhibitor of cytochrome P450 1B1 which has a very high degree of selectivity for P450 1B1 versus both P450 1A1 (>50-fold) and P450 1A2 (>520-fold). In vitro it inhibits cancer cell growth. Synonyms: 1-[(E)-2-(2,4-dimethoxyphenyl)ethenyl]-3,5-dimethoxybenzene 2,3',4,5'-tetramethoxystilbene 2,4,3',5'-tetramethoxystilbene 3,5,2',4'-tetramethoxy-trans-stilbene TMS cpd. Grades: >98 %. CAS No. 24144-92-1. Molecular formula: C18H20O4. Mole weight: 300.35. | |
| Tobanium hydrochloride | Tobanium hydrochloride is a long-acting beta-blocker. lt was particularly efficient in moderately hypertensive patients and in some highly-hypertensive ones, which had not responded to propranolol. Uses: Tobanium hydrochloride was particularly efficient in moderately hypertensive patients and in some highly-hypertensive ones. Synonyms: Cloranolol hydrochloride; GYKI41099; GYKI-41099; Tobanum HCl; Cloranolol HCl; 1-(tert-Butylamino)-3-(2,5-dichlorophenoxy)propan-2-ol hydrochloride. Grades: 98%. CAS No. 54247-25-5. Molecular formula: C13H20Cl3NO2. Mole weight: 328.66. | |
| tocilizumab | Tocilizumab is a humanized monoclonal antibody resistant against the interleukin-6 receptor (IL-6R). It is an immunosuppressive agent commonly used for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis. Actemra (tocilizumab) 162 mg syringe for subcutaneous injection and Actemra 162 mg auto-injector for subcutaneous injection was approved in Japan for the treatment of Takayasu arteritis (TAK) and giant cell arteritis (GCA), as well as its intravenous injection was approved by FDA for severe cytokine release syndrome (CRS). Uses: The treatment of rheumatoid arthritis (ra), systemic juvenile idiopathic arthritis, takayasu arteritis (tak), giant cell arteritis (gca), severe cytokine release syndrome (crs), etc. Synonyms: Anti-Human IL6R, Humanized Antibody; Actemra; R 1569; RoActemra; Atlizumab; Actemra 200; R1569; R-1569. Grades: ≥95%. CAS No. 375823-41-9. Molecular formula: C6428H9976N1720O2018S42. Mole weight: 145000. | |
| Tolfenamic Acid | Tolfenamic Acid is a COX-2 inhibitor with IC50 of 0.2 μM. Synonyms: 2-[(3-chloro-2-methylphenyl)?amino]?-benzoic acid. CAS No. 13710-19-5. Molecular formula: C14H12ClNO2. Mole weight: 261.7. | |
| Tolmetin-acyl-beta-D-Glucuronide | One of the impurities of Tolmetin, which is a non-steroidal anti-inflammatory agent used in the treatment of steoarthritis and rheumatoid arthritis. Synonyms: 1-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetate] β-D-Glucopyranuronic Acid. CAS No. 71595-19-2. Molecular formula: C21H23NO9. Mole weight: 433.41. | |
| Tomeglovir | Tomeglovir is a potent and selective inhibitor of cytomegalovirus (CMV) replication. Synonyms: BAY 38-4766; N-[4-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]phenyl]-3-hydroxy-2,2-dimethylpropanamide. Grades: 99.45%. CAS No. 233254-24-5. Molecular formula: C23H27N3O4S. Mole weight: 441.54. | |
| Topiramate Desacetal Impurity (4,5-diol-Topiramate) | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate Topiramate desacetal impurity. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.30. | |
| Topiramate D-galactopyranose | Topiramate D-galactopyranose is a scientifically formulated pharmaceutical compound, used for studying epilepsy and migraine headaches. Marrying the prowess of anticonvulsant properties and the ability to curb repetitive neuronal firing, it exhibits a mechanism of action rooted in augmenting GABA receptor activity while diminishing glutamate receptor activity. Molecular formula: C18H31NO13S. Mole weight: 501.50. | |
| Topiramate Didesacetal Impurity | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: β-D-Fructopyranose 1-Sulfamate. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.24. | |
| Topiramate Dimer Impurity | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Molecular formula: C24H39NO13S. Mole weight: 581.63. | |
| Topiramate Impurity 1 | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3. CAS No. 106881-35-0. Molecular formula: C12H19N3O8S. Mole weight: 365.36. | |
| Topiramate Impurity 2 | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 4,5-O-(1-Methylethylidene)-b-D-fructopyranose 1-sulfamate. CAS No. 851957-35-2. Molecular formula: C9H17NO8S. Mole weight: 299.30. | |
| Topiramate impurity B | Topiramate Impurity B is a pharmaceutical offering, aiding in anchoring the assessment of quality and purity within topiramate formulations, an eminent remedy for epilepsy research and migraine prophylaxis. Synonyms: Topiramate related compound B. | |
| Topiramate impurity C | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: (2,2,7,7-tetramethyl-tetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4',5'-d] pyran-3a-yl)methyl sulfurochloridoate. Molecular formula: C12H19ClO8S. Mole weight: 358.79. | |
| Topiramate Impurity D | Cas No. 25018-67-1. | |
| Topiramate N-Methyl Impurity | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: N-Methyl Topiramate; 2,3:4,5-bis-O-(1-Methylethylidene)-β-D-Fructopyranose 1-(N-Methylsulfamate); 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose Methylsulfamate. CAS No. 97240-80-7. Molecular formula: C13H23NO8S. Mole weight: 353.39. | |
| Topiramate Related Compound A | One of the impurities of Topiramate, which is a fuctopyranose derivative and has been found to be used as an anticonvulsant agent. Synonyms: 2,3:4,5-Di-O-isopropylidene-β-D-fructopyranose; 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose; USP Topiramate Related Compound A; Diacetonefructose; ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl)methanol. Grades: ≥98%. CAS No. 20880-92-6. Molecular formula: C12H20O6. Mole weight: 260.28. | |
| Toripalimab | Toripalimab is a humanized monoclonal antibody against PD-1. Toripalimab binds to PD-1 and blocks the interaction with its ligands. Toripalimab has exhibited primary anti-tumor effects in tumors such as melanoma, lung cancer, digestive tract tumors, hepatobiliary and pancreatic tumors, neuroendocrine neoplasms, nasopharyngeal carcinoma and urothelial carcinoma. CAS No. 1924598-82-2. | |
| Totrombopag | Totrombopag is being developed by GlaxoSmithKline, which a back-up compound for eltrombopag (SB-497115). Synonyms: SB-559448; SB 559448; SB559448; LGD-4665; 2-(3,4-Dimethylphenyl)-4-((2-hydroxy-3'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)diazenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one. CAS No. 376592-42-6. Molecular formula: C25H22N8O2. Mole weight: 466.49. | |
| Tovetumab | Tovetumab is a human IgG2κ monoclonal antibody that binds to human platelet-derived growth factor receptor alpha (PDGFRα) and blocks receptor signal transduction by PDGF ligands. Synonyms: MEDI-575; MEDI 575; MEDI575. CAS No. 1243266-04-7. | |
| TP-110 | TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases. Synonyms: TP110; TP 110; Tyropeptin A 7. Grades: 98%. CAS No. 688737-95-3. Molecular formula: C37H41N3O6. Mole weight: 623.75. | |
| TPCS2a | TPCS2a, also know as, tetraphenyl chlorin disulfonate, is a meso-tetraphenylchlorin substituted by two adjacent sulfonated groups with potential photosensitizing activity. Upon administration, tetraphenyl chlorin disulfonate incorporates into the cell endosome and lysosome membranes. Subsequently, cytotoxic agents are administered and accumulate in endosomal and lysosomal compartments; upon local activation by light, tetraphenyl chlorin disulfonate produces reactive oxygen species (ROS), such as singlet oxygen, damaging endo/lysosomal membranes and accumulated cytotoxic agents are released into the tumor cell cytosol. This photochemical internalization (PCI) method can enhance the efficacy and selectivity of cytotoxic agents. Synonyms: Benzenesulfonic acid, 4,4'-(7,8-dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis-; 4,4'-(7,8-Dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis[benzenesulfonic acid]; Amphinex; Di(monoethanolammonium) meso-tetraphenyl chlorin disulfonate; Fimaporfin A; Tetraphenyl chlorin disulfonate. Grades: ≥95%. CAS No. 501083-97-2. Molecular formula: C44H32N4O6S2. Mole weight: 776.88. | |
| TPEN | TPEN is a heavy metal chelator that acts as an intracellular chelator of proteomic Zn2+. TPEN decreases intracellular zinc levels, and induces apoptosis in HeLa and cultured human retinal pigment epithelium (RPE) cells. Synonyms: TPEN; TPEDA. N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine; N1,N1,N2,N2-Tetrakis(pyridin-2-ylmethyl)ethane-1,2-diamine. Grades: ≥98% by HPLC. CAS No. 16858-02-9. Molecular formula: C26H28N6. Mole weight: 424.54. | |
| TPI-287 | TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis. Synonyms: TPI-287; TPI287; ARC-100; ARC 100; ARC100; TPI 287. CAS No. 849213-15-6. Molecular formula: C46H63NO15. Mole weight: 870.00. | |
| TPT-172 | TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Uses: For research used only. Synonyms: TPT-172; TPT 172; TPT172; thiophene thiourea derivative. R33; R 33; R-33. Grades: 98%. CAS No. 32415-42-2. Molecular formula: C6H9ClN2S2. Mole weight: 208.72. | |
| Tradipitant | Tradipitant, also known as VLY-686 and LY686017, is the 2nd generation neurokinin-1 receptor antagonist, which showed activity in preclinical anxiety models. LY686017 may be a possible therapy for alcoholism. LY686017 can be also served as a suitable chemical platform for future imaging ligand development. (last update: ). Synonyms: LY686017; LY 686017; LY-686017; VLY 686; VLY686; VLY-686. Grades: 99%. CAS No. 622370-35-8. Molecular formula: C28H16ClF6N5O. Mole weight: 587.91. | |
| Tralokinumab | Tralokinumab is a humanized monoclonal antibody that binds to IL-13 and inhibits the interaction of IL-13 and its receptor. Tralokinumab has been used for the treatment of atopic dermatitis (AD). Synonyms: Adtralza; Adbry; CAT-354. CAS No. 1044515-88-9. | |
| Trandolaprilat acyl-D-glucuronide | Trandolaprilat acyl-D-glucuronide is an invaluable biomedical compound facilitating the research of diverse cardiovascular ailments. It arises as a metabolite ensuing from the administration of Trandolapril, a potent compound targeting hypertension and heart failure. Molecular formula: C28H38N2O11. Mole weight: 578.61. | |
| trans-3-Benzoyloxy cotinine 2,3,4-tri-O-acetyl-N-b-D-glucuronide methyl ester bromide | trans-3-Benzoyloxy cotinine 2,3,4-tri-O-acetyl-N-b-D-glucuronide methyl ester bromide is a potent biomedical compound, emerging as a breakthrough tool in studying nicotine addiction and associated pathological conditions. By exerting a profound antagonistic influence on nicotine receptors, this astounding compound inhibits the indulgence of nicotine. Synonyms: (2S-trans)-3-[4-(Benzoyloxy)-1-methyl-5-oxo-2-pyrrolidinyl]-1-(2,3,4-tri-O-acetyl-6-methyl-b-D-glucopyranuronosyl)-pyridinium bromide. CAS No. 146490-58-6. Molecular formula: C30H33BrN2O12. Mole weight: 693.49. | |
| trans-3-Hydroxycotinine-O-b-D-glucuronide D3 sodium salt | trans-3-Hydroxycotinine-O-b-D-glucuronide D3 sodium salt is a pivotal substance employed, serving as an invaluable compound for investigating both nicotine metabolism and addiction phenomena. It is widely applied in studies pertaining to smoking cessation practices, nicotine dependency and diverse afflictions linked to tobacco consumption. Molecular formula: C16H16N2O8D3 Na. Mole weight: 393.34. | |
| trans-beta-D-Glucopyranosyl methylacetoacetate | trans-beta-D-Glucopyranosyl methylacetoacetate is an intriguing derivative of glucose illuminating a path towards revolutionizing the research of diabetes and other intertwined metabolic ailments. It showcases propitious characteristics for precisely modulating the intricate web of glucose metabolism and sensitizing insulin responsiveness. Synonyms: [(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] 2-methyl-3-oxobutanoate; (2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl 2-methyl-3-oxobutanoate. CAS No. 55018-21-8. Molecular formula: C11H18O8. Mole weight: 278.26. | |
| trans-Zeatin-7-glucoside | Trans-Zeatin-7-glucoside, a phytohormone of the cytokinin family, has been rigorously studied for its capacity to enhance plant growth and development. Furthermore, this crucial molecule has shown immense promise in the neurodegenerative therapeutic domain. Pathologies like Alzheimer's and Parkinson's have been curbed by trans-Zeatin-7-glucoside's medicinal capability making it a pivotal molecule for those who seek to enhance the health and wellbeing of both plants and animals alike. Synonyms: 6-((E)-4-Hydroxy-3-methylbut-2-enylamino)-7-b-D-glucopyranosyl purine. CAS No. 38165-56-9. Molecular formula: C16H23N5O6. Mole weight: 381.38. | |
| trans-Zeatin-9-glucoside | trans-Zeatin-9-glucoside is a pivotal compound widely utilized in the research of diverse ailments like chronic inflammation, oxidative stress and cellular impairment. By modulating crucial cellular mechanisms, it aids in studying manifestations linked to cardiovascular disorders and neurodegenerative pathologies. Synonyms: 6-((E)-4-hydroxy-3-methylbut-2-enylamino)-9-b-Dglucopyranosylpurine. CAS No. 51255-96-0. Molecular formula: C16H23N5O6. Mole weight: 381.38. | |
| trans-Zeatin-9-glucuronide | trans-Zeatin-9-glucuronide is a highly efficacious and medically significant compound, finding extensive employment in studying diverse ailments such as arthritand neurodegenerative disorders. It has commendable anti-inflammatory attributes. Molecular formula: C16H21N5O7. Mole weight: 395.37. | |
| trans-Zeatin-O-glucoside | Trans-Zeatin-O-glucoside, a plant growth hormone utilized within the biomedical industry for investigating cytokinins' effects on cellular response and differentiation. It boasts potential as a neurodegenerative disease therapeutic agent due to its remarkable neuron survival and regeneration-enhancing capabilities. Synonyms: 6-((E)-4-b-D-Glucopyranosyloxy-3-methylbut-2-enylamino) purine. CAS No. 56329-06-7. Molecular formula: C16H23N5O6. Mole weight: 381.38. | |
| trans-Zeatin-o-glucuronide | trans-Zeatin-o-glucuronide is a biomedically significant product, classified as a glucuronide conjugate of the pivotal cytokinin trans-zeatin. This compound exerts a critical influence on plant growth and development. Leveraging its distinctive structural attributes, trans-zeatin-o-glucuronide aids in the research of cancer, diabetes and neurodegenerative ailments. Synonyms: trans-Zeatin-O-beta-D-glucuronide; 147663-51-2. CAS No. 147663-51-2. Molecular formula: C16H21N5O7. Mole weight: 395.37. | |
| Tranylcipromine | Tranylcypromine, an amphetamine derivative, has been found to be a MAO inhibitor that could be used an antidepressant agent and anxiolytic drug. Synonyms: Cyclopropanamine, 2-phenyl-, (1R,2S)-rel-;Tranylcypromine (base and/or unspecified salts);dl-Tranylcypromine;SKF-385;Transamine[thymoleptic];C07155. Grades: 98%. CAS No. 155-09-9. Molecular formula: C9H11N. Mole weight: 133.19. | |
| Trehalose octaacetate | Trehalose octaacetate, an esteemed biomedical marvel, takes center stage in combating the realm of neurodegenerative afflictions. Embarking on a noble expedition to tame the vicious Alzheimer's and Parkinson's, this formidable substance assumes the unsung role of a neuroprotective sentinel. Synonyms: 2,3,4,6,2,3,4,6-Octa-O-acetyl-a,a-trehalose. CAS No. 25018-27-3. Molecular formula: C28H38O19. Mole weight: 678.59. | |
| Tremuloidin | Tremuloidin, an organic compound extracted from select botanical species, has garnered substantial attention within the biomedical sector owing to its remarkable anticancer properties. Exhibiting robust inhibition against diverse malignancies, this naturally occurring substance presents itself as a viable contender for pioneering cancer therapeutics. Synonyms: 2-Benzoylsalicin. CAS No. 529-66-8. Molecular formula: C20H22O8. Mole weight: 390.38. | |
| Tretinoin Glucuronide | Tretinoin Glucuronide is a biliary metabolite of Vitamin A that stimulates the growth of vitamin A-deficient rats in vivo. All-trans-RAG is similarly active to all-trans-RA in stimulating the differentiation and inhibiting the growth of HL-60 cells, but is clearly less cytotoxic than its aglycon all-trans-RA. Synonyms: RAG; All-trans-Retinoyl b-D-glucopyranuronic acid. CAS No. 401-10-5. Molecular formula: C26H36O8. Mole weight: 476.56. | |
| Trichloroethyl b-D-glucuronide | Trichloroethyl b-D-glucuronide, a compound of great scientific significance, is a vital urinary biomarker employed in the study of chemical exposure, particularly to trichloroethylene. Its invaluable function extends to biomedicine, where it is utilized to examine the interplay between glucuronidation and drug metabolism and elimination. This multifaceted compound promises to continue revolutionizing the field of chemical and biomedical research. CAS No. 97-25-6. Molecular formula: C8H11Cl3O7. Mole weight: 325.53. | |
| Triclofenol Piperazine | Triclofenol piperazine is used for the treatment of patients infected with parasite such as hookworms. Uses: Triclofenol piperazine is used for the treatment of patients infected with parasite such as hookworms. Synonyms: CI-416; CI416; CI 416; Triclofenol piperazate; Triclofenol piperazina; Piperazin-2-one compound with 2,4,5-trichlorophenol. Grades: 98%. CAS No. 5714-82-9. Molecular formula: C16H16Cl6N2O2. Mole weight: 481.03. | |
| Tridihexethyl | Tridihexethyl is a synthetic anticholinergic agent. It has a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. lt binds the muscarinic acetylcholine receptor and may block all three types of muscarinic receptors including M-1 receptors in the CNS and ganglia, M-2 receptors in the heart and M-3 receptors at the parasympathetic NEJ system. lt inhibits vagally mediated reflexes by antagonizing the action of acetylcholine. lt is an anticholinergic, antimuscarinic and antispasmodic drug. It may be used to treat acquired nystagmus or peptic ulcer disease in combination with other drugs. Uses: Tridihexethyl has a pronounced antispasmodic and antisecretory effect on the gastrointestinal tract. lt is an anticholinergic, antimuscarinic and antispasmodic drug. it may be used to treat acquired nystagmus or peptic ulcer disease in combination with ot. Synonyms: Propethonum; 3-cyclohexyl-N,N,N-triethyl-3-hydroxy-3-phenylpropan-1-aminium; N,N,N-Triethyl-3-cyclohexyl-3-hydroxy-3-phenylpropylammonium. Grades: 98%. CAS No. 60-49-1. Molecular formula: C21H36NO. Mole weight: 318.52. | |
| Trifluoroacetamidopropyl b-D-galactopyranoside | Trifluoroacetamidopropyl b-D-galactopyranoside is a renowned chemical compound extensively employed in the biomedical sector, serving for studying carbohydrate-protein interactions, particularly for maladies associated with carbohydrate metabolism. | |
| Tri-Lewis x-APE, HSA conjugate | Tri-Lewis x-APE, HSA conjugate is a biomedical product utilized for targeted drug delivery and imaging applications. By conjugating Human Serum Albumin (HSA) with the Tri-Lewis x-APE moiety, this product enables effective research of cancers expressing Lewis x antigens, such as lung, breast and ovarian cancer. Synonyms: Tri-Lex-APE-HSA. | |
| Trimazosin hydrochloride | Trimazosin hydrochloride is a sympatholytic alpha blocker. It is used in the treatment of hypertensive patients failing to respond to thiazides. It is useful in therapy as potent antihypertensive agents. Uses: Trimazosin hydrochloride is useful in therapy as potent antihypertensive agents. Synonyms: Trimazosin HCl; 4-(4-Amino-6,7,8-trimethoxy-2-quinazolinyl)-1-piperazinecarboxylic Acid 2-Hydroxy-2-methylpropyl Ester Hydrochloride; CP 19106-1. Grades: 98%. CAS No. 53746-46-6. Molecular formula: C20H32ClN5O7. Mole weight: 489.95. | |
| Trimethobenzamide hydrochloride | Trimethobenzamide hydrochloride is the hydrochloride salt form of trimethobenzamide, which is a benzamide derivative with antiemetic property. It is an orally available, antiemetic agent used in the therapy of nausea and vomiting and gastrointestinal, viral and other illnesses. It is generally considered the most potent antiemetic that does not have effects on the serotonergic, dopaminergic, or histaminergic systems. It inhibits the chemoreceptor trigger zone (CTZ), an area in the medulla oblongata through which emetic impulses are conveyed to the vomiting center, thereby suppressing nausea and vomiting. It is also used in the treatment of Parkinson's disease. It has been withdrawn from the market. Uses: Trimethobenzamide hydrochloride is an orally available, antiemetic agent used in the therapy of nausea and vomiting and gastrointestinal, viral and other illnesses. it is also used in the treatment of parkinson's disease. Synonyms: Ro 2-9578; Tebamide; Ticon; Trimethobenzamide monohydrochloride; N-(p-(2-(dimethylamino)ethoxy)benzyl)-3,4,5-trimethoxybenzamide hydrochloride; Ametik hydrochloride; 4-(2-Dimethylaminoethoxy)-N-(3,4,5-trimethoxybenzoyl)benzylamine Hydrochloride; Anaus; Tigan Hydrochloride; Xametina. Grades: 98%. CAS No. 554-92-7. Molecular formula: C21H29ClN2O5. Mole weight: 424.92. | |
| Trimethylsilyl-2,3,4,6-tetra-O-benzyl-b-D-glucopyranoside | Trimethylsilyl-2,3,4,6-tetra-O-benzyl-b-D-glucopyranoside is a valuable compound used in the synthesis of various glycosides and oligosaccharides. It plays a crucial role in the biomedical industry by enabling the development of drugs for studying diseases related to abnormal carbohydrate metabolism, such as diabetes and glycogen storage disorders. CAS No. 89825-08-1. Molecular formula: C37H42O8. Mole weight: 614.72. | |
| Trimethylsilyl-meso-inositol | Trimethylsilyl-meso-inositol is a formidable compound widely employed in studying diabetes, metabolic disorders and neurodegenerative afflictions. It can facilitate glucose metabolism regulation and exuding antioxidative prowess. Synonyms: trimethyl-[2, 3, 4, 5, 6-pentakis (trimethylsilyloxy) cyclohexyl]oxysilane; Trimethylsilyl-meso-inositol; myo-inositol-TMS; mio-Inositol,hexakis-TMS; Hexakis-O-trimethylsilyl-myo-inositol. CAS No. 2582-79-8. Molecular formula: C24H60O6Si6. Mole weight: 613.24. | |
| Trimetoquinol hydrochloride | Trimetoquinol hydrochloride is a beta2-adrenoceptor receptor agonist. Uses: Adrenergic beta-agonists. Synonyms: (S)-1,2,3,4-Tetrahydro-6,7-dihydroxy-1-(3,4,5-trimethoxybenzyl)isoquinolinium chloride; Trimetoquinol HCl. Grades: 95%. CAS No. 18559-59-6. Molecular formula: C19H23NO5.HCl. Mole weight: 381.86. | |
| Tri-O-acetyl-4,6-O-benzylidene-D-glucopyranose | Tri-O-acetyl-4,6-O-benzylidene-D-glucopyranose is a paramount compound, finding widespread application in the synthesis of diverse drugs and derivatives. Its pivotal role manifests in studying afflictions like cancer, viral infections and inflammation. Synonyms: (4AR,7R,8S,8aR)-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-6,7,8-triyl triacetate; SCHEMBL7563649; D-Glucopyranose,4,6-O-(phenylmethylene)-,triacetate(9ci). CAS No. 257925-66-9. Molecular formula: C19H22O9. Mole weight: 394.4. | |
| Tri-O-acetyl-4-pentulosonic acid methyl ester | Tri-O-acetyl-4-pentulosonic acid methyl ester is a compound, showcasing remarkable versatility in drug synthesis and pharmaceutical production. By intricately intersecting with distinct biochemical pathways, this compound harbors promising potential for studying an array of ailments. Molecular formula: C12H16O9. Mole weight: 304.25. | |
| Tri-O-acetyl-b-D-GlcNAc-Fmoc Asn tert-Butyl Ester | Tri-O-acetyl-b-D-GlcNAc-Fmoc Asn tert-Butyl Ester is a valuable compound acting as a protecting tool during peptide synthesis, specifically for the amino acid asparagine (Asn). This product plays a crucial role in producing high-quality peptides by safeguarding the Asn residue from undesired side reactions. It ensures efficient peptide assembly and aids in the development of drugs targeting various diseases. Molecular formula: C34H45N3O13. Mole weight: 703.73. | |
| Tri-O-benzyl-isofagomine hydrochloride | | |
| Triphendiol | Triphendiol (NV-196) is a synthetic isoflavene. Triphendiol (NV-196) is another investigational drug in the Marshall Edwards, Inc., oncology drug pipeline. Triphendiol is broadly cytostatic and cytotoxic against most forms of human cancer cells in vitro, and has been shown to cause cell cycle arrest (or stop cells increasing in number) and to induce apoptosis (or initiate programmed cell death) in various cancer cell lines. Synonyms: Triphendiol; NV-196; NV 196; NV196. Grades: 98%. CAS No. 1213777-80-0. Molecular formula: C22H20O4. Mole weight: 348.40. | |
| Trisethyleneiminoquinone | Trisethyleneiminoquinone is an aziridinylbenzoquinone-based alkylating agent. It can react with DNA to form intrastrand crosslinks. It has potential antineoplastic activity and is used mainly for ovarian tumors. Uses: Trisethyleneiminoquinone has potential antineoplastic activity and is used mainly for ovarian tumors. Synonyms: A 163; A 163; A 163; Triaziquone; Trenimon; Trenimone; Triazichon; 1,1',1''-(3,6-Dioxo-1,4-cyclohexadiene-1,2,4-triyl)tris aziridine. Grades: 98%. CAS No. 68-76-8. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
| Trofosfamide | Trofosfamide is an orally bioavailable oxazaphosphorine prodrug with antineoplastic activity. Trofosfamide (TFF) is metabolized predominantly to the cyclophosphamide analogue ifosfamide (IFO), which is then metabolized by liver cytochrome P450s to the active isophosphoramide mustard (IPM). IPM alkylates DNA to form DNA-DNA cross-links, which may result in inhibition of DNA, RNA and protein synthesis, and tumor cell apoptosis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). Synonyms: Trofosfamide; Ixoten; Genoxal Trofosfamida; A-4828; A 4828; A4828. Grades: 98%. CAS No. 22089-22-1. Molecular formula: C9H18Cl3N2O2P. Mole weight: 323.58. | |
| Troglitazone | Troglitazone, PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity, which was approved for the treatment of insulin resistance and hyperglycemia in Type II diabetes, but was withdrawn from the market due to hepatotoxicity. It binds to the PPARγ ligand-binding domain (LBD) but fails to induce interaction of the PPARγ LBD with the transcriptional coactivators SRC-1, TIF2, AIB1, p300, or TRAP220. It also induces cell cycle arrest and apoptosis in several cancer cell lines. It displays no activity at PPARα or PPARδ receptors and displays anti-invasive effect on human breast cancer cells. It also inhibits cell growth of hematopoietic cell lines and inhibits lamellipodia formation and actin polymerization. Uses: Hypoglycemic agents. Synonyms: CI-991; CI991; CI 991; CS-045; CS 045; CS045; GR 92132X; GR92132X; Prelay; Troglitazone; Rezulin, Resulin, Romozin, Noscal. Grades: >98%. CAS No. 97322-87-7. Molecular formula: C24H27NO5S. Mole weight: 441.54. | |
| Trovafloxacin mesylate | Trovafloxacin mesylate is a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. It does not inhibit connexin 43 gap junction or PANX2. It leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1. It is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. It is also an inhibitor of DNA topoisomerase and gyrase. Uses: Fluorinated quinolone antibacterial. trovafloxacin mesylate blocks the activity of dna gyrase and topoisomerase iv, enzymes essential in the repliction, transcription, and repair of bacterial dna. Synonyms: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan; 1,8-Naphthyridine-3-carboxylic acid, 7-[(1R,5S)-6-amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, methanesulfonate (1:1). Grades: ≥95%. CAS No. 147059-75-4. Molecular formula: C21H19F3N4O6S. Mole weight: 512.46. | |
| Truxima | Truxima is a bioanalogue of rituximab used for the treatment of all the indications of rituximab such as non-Hodgkin's lymphoma, chronic lymphocytic leukaemia (CLL), severe rheumatoid arthritis and granulomatosis with polyangiitis. Uses: All the indications of rituximab. | |
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