BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| CP 80080 | CP 80080, a quinolinecarboxylic acid derivative, has been found to influencing DNA cleavage slightly and could probably be used in th anticancer studies. Synonyms: CP 80080; CP80080; CP-80080; CP-80,080; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(4-methoxyphenyl)-4-oxo-. Grades: 98%. CAS No. 152247-02-4. Molecular formula: C20H16FNO4. Mole weight: 353.34. |  |
| CP-870893 | CP-870893 is a potent and selective agonist of CD40 and a fully human IgG2 mAb. Synonyms: CP-870,893; CP 870,893; CP870,893; CP870893. | |
| CP8754 | CP8754 is a bio-active chemical compound. Synonyms: CP-8754; CP 8754; Carbamic acid, cyclopropyl-, (4aR,5R,6R,7R)-2,4,4a,5,6,7-hexahydro-7-methoxy-3,4a,5-trimethyl-2-oxonaphtho(2,3-b)furan-6-yl ester. Grades: 98%. CAS No. 532435-68-0. Molecular formula: C20H25NO5. Mole weight: 359.42. | |
| CP-91149 | CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Synonyms: CP 91149; CP91149; 5-Chloro-1H-indole-2-carboxylic acid ((1S,2R)-1-benzyl-2-dimethylcarbamoyl-2-hydroxy-ethyl)-amide. Grades: >98%. CAS No. 186392-40-5. Molecular formula: C21H22ClN3O3. Mole weight: 399.87. | |
| CPYPP | CPYPP has been found to be a DOCK2-Rac1 interaction inhibitor and could probably attenuate HER2-mediated breast cancer cell migration. Synonyms: 4-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione. Grades: ≥98% by HPLC. CAS No. 310460-39-0. Molecular formula: C18H13ClN2O2. Mole weight: 324.76. | |
| CR8 | CR8 is a potent and selective inhibitor of CDK. CR8 is a more potent pyridyl analogue of roscovitine. In comparison to roscovirtine, the compound gains in potency toward CK1, which is involved in amyloid-β formation. The R-CR8 enantiomer is slightly more potent than S. CR8 is around 30 times more potent at cellular assay then roscovitine. (R)?-CR8 induces apoptosis and has neuroprotective effect. (R)-CR8 acts as a molecular glue degrader that depletes cyclin K. Synonyms: (R)-CR8; CR 8; CR-8. Grades: 98%. CAS No. 294646-77-8. Molecular formula: C24H29N7O. Mole weight: 431.544. | |
| CRAC inhibitor 44 | CRAC inhibitor 44 is a potent and selective CRAC ion channel inhibitor suppressing CRAC ion channel activity and the production of IL-2, IL-4, IL-5, IL-13, GM-CSF, TNF-α, and IFN&gamma. Grades: 99%. CAS No. 944917-72-0. Molecular formula: C22H19F2N3OS. Mole weight: 411.47. | |
| CRAC intermediate 1 | A significant intermediate in the production of sorts of CRAC channel inhibitors. Uses: A significant intermediate in the production of sorts of crac channel inhibitors. Synonyms: CRAC intermediate 1; SCHEMBL706559; UMBVHXNGQIFPCN-UHFFFAOYSA-N; AKOS010652441; CS-3896; CS 3896; CS3896. Grades: 98%. CAS No. 1249343-86-9. Molecular formula: C10H7F2N3O. Mole weight: 223.18. | |
| Crolibulin | Crolibulin, also known as EPC2407 and crinobulin, is a small molecule tubulin polymerization inhibitor with potential antineoplastic activity. Microtubulin inhibitor EPC2407 binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of tubulin into microtubules, which may result in cell cycle arrest, the induction of apoptosis, and the inhibition of tumor cell proliferation. As a vascular disruption agent (VDA), this agent also disrupts tumor neovascularization, which may result in a reduction in tumor blood flow and tumor hypoxia and ischemic necrosis. Synonyms: EPC2407; EPC 2407; EPC-2407; (R)-2,7,8-triamino-4-(3-bromo-4,5-dimethoxyphenyl)-4H-chromene-3-carbonitrile. CAS No. 1000852-17-4. Molecular formula: C18H17BrN4O3. Mole weight: 417.263. | |
| CTA056 | CTA056 is a potent and selective ITK inhibitor (interleukin-2-inducible T-cell kinase inhibitor). ITK is a member of the Btk (Bruton's tyrosine kinase) family of tyrosine kinases, plays an important role in normal T-cell functions and in the pathophysiology of both autoimmune diseases and T-cell malignancies. CTA056 exhibits the highest inhibitory effects toward Itk, followed by Btk and endothelial and epithelial tyrosine kinase. Among the 41 cancer cell lines analyzed, CTA056 selectively targets acute lymphoblastic T-cell leukemia and cutaneous T-cell lymphoma. CTA056 may be potential therapeutic agent for the treatment of T-cell leukemia and lymphoma. Synonyms: CTA-056; CTA 056; 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one. Grades: 98%. CAS No. 1265822-30-7. Molecular formula: C35H34N6O. Mole weight: 554.69. | |
| Curcumin β-D-Glucuronide | Curcumin β-D-Glucuronide is a metabolite of Curcumin in hepatic tissue and portal blood. Synonyms: 4-[(1E,6E)-7-(4-Hydroxy-3-methoxyphenyl)-3,5-dioxo-1,6-heptadien-1-yl]-2-methoxyphenyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 227466-72-0. Molecular formula: C27H28O12. Mole weight: 544.5. | |
| Cusatuzumab | Cusatuzumab is a humanized anti-CD70 monoclonal antibody. Cusatuzumab was shown to eliminate leukemia stem cells (LSCs) in vitro and in xenotransplantation experiments, which triggers gene signatures related to myeloid differentiation and apoptosis. CAS No. 1864871-20-4. | |
| CW 008 | CW 008 is a cAMP/PKA/CREB pathway activator promoting osteogenic differentiation of human bone marrow derived MSCs in vitro, and it also increases bone mass and bone volume density in ovariectomized mice. Uses: Promoting osteogenic differentiation of human bone marrow. Synonyms: CW-008; 4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide. Grades: >98%. CAS No. 1134613-19-6. Molecular formula: C21H14F2N6O2. Mole weight: 420.38. | |
| CX 4945 hydrochloride | CX 4945 hydrochloride is an orally bioactive and ATP-competitive casein kinase 2 (CK2) inhibitor. CX 4945 inhibits proliferation and migration in a panel of cancer cell lines which overexpresses CK2. Uses: Antitumor agent. Synonyms: CX 4945 hydrochloride; CX-4945 hydrochloride; CX4945 hydrochloride; Silmitasertib HCl; Silmitasertib hydrochloride. Grades: 98%. CAS No. 2108312-01-0. Molecular formula: C19H12ClN3O2.HCl. Mole weight: 386.23. | |
| CX-4945 sodium salt | CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively. Synonyms: Silmitasertib sodium salt; CX-4945 sodium salt; CX 4945 sodium salt; CX4945 sodium salt. Grades: >98%. CAS No. 1309357-15-0. Molecular formula: C19H11ClN3NaO2. Mole weight: 371.75. | |
| CX-5011 | CX-5011 is a very potent and selective CK2 inhibitor, which induces cell death in tumor cells. Synonyms: CX5011; CX 5011; Pyrimido[4,5-c]quinoline-8-carboxylic acid, 5-[(3-ethynylphenyl)amino]-. Grades: 98%. CAS No. 1009821-06-0. Molecular formula: C20H12N4O2. Mole weight: 340.34. | |
| CX-5461 | CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Synonyms: CX-5461; CX 5461; CX5461. CAS No. 1138549-36-6. Molecular formula: C27H27N7O2S. Mole weight: 513.62. | |
| CX-6258 Hydrochloride | CX-6258 shows antiproliferative activity against a panel of human cancer cell lines with IC50 of 0.02-3.7 μM, mostly sensitive to acute leukemia cell lines. Synonyms: CX-6258 HCl; CX 6258 hydrochloride; CX 6258 HCl; CX6258 HCl. Grades: >98%. CAS No. 1353859-00-3. Molecular formula: C26H25Cl2N3O3. Mole weight: 498.40. | |
| Cyanidin-3,5-di-O-glucoside | Cyanidin-3,5-di-O-glucoside is a renowned phytochemical, epitomizing its inherent antioxidant potentials. It is used for studying cardiovascular ailments, diabetes and cancer. Synonyms: Cyanin chloride. CAS No. 2611-67-8. Molecular formula: C27H31O16 Cl. Mole weight: 646.99. | |
| Cyanidin-3-O-arabinose chloride | Cyanidin-3-O-arabinose chloride is a natural compound which can be isolated from Vaccinium myrtillus and Vaccinium padifolium. Synonyms: Cyanidin-3-Arabinoside. CAS No. 27214-72-8. Molecular formula: C20H19O10Cl. Mole weight: 454.81. | |
| Cyanidin-3-O-coumaroyl sambubioside-5-glucoside | Cyanidin-3-O-coumaroyl sambubioside-5-glucoside is a multifaceted compound with commendable antioxidant and anti-inflammatory attributes used for studying cardiovascular, diabetic, oncological and neurodegenerative maladies. Synonyms: Cyanidin 3-O-b-(6''-O-E-p-coumaroyl-sambubioside)-5-O-b-glucopyranoside; Cyanidin 3-coumsamb-5-glucoside. Molecular formula: C43H45O24F3. Mole weight: 1002.80. | |
| Cyanidin-3-O-galactoside chloride | Cyanidin-3-O-galactoside chloride is a natural compound which can be isolated from Vaccinium myrtillus, showing anti-obesity and hypolipidemic effects. Synonyms: Cyanidin-3-Galactoside; Idaein chloride; Ideanin. CAS No. 27661-36-5. Molecular formula: C21H21O11 Cl. Mole weight: 484.85. | |
| Cyanidin-3-O-glucuronide | Cyanidin-3-O-glucuronide, an endogenous chemical constituent present in an assortment of fruits and vegetables, has captivated researchers due to its inherent antioxidative and anti-inflammatory attributes. CAS No. 775284-61-2. Molecular formula: C21H19O12 Cl. Mole weight: 498.82. | |
| Cyanidin-3-O-lathyroside chloride | Cyanidin-3-O-lathyroside chloride is a remarkable biomedical compound, renowned for its substantial antioxidant and anti-inflammatory attributes. This compound is used for studying oxidative stress-mediated conditions like neurodegenerative disorders and cardiovascular diseases. Synonyms: cyanidin-3-o-lathyroside chloride; 31073-32-2; AKOS040763596; FS-7431. CAS No. 31073-32-2. Molecular formula: C26H29O15 Cl. Mole weight: 616.95. | |
| Cyanidin-3-O-rhamnoside chloride | Cyanidin-3-O-rhamnoside chloride is a potent compound found in various fruits and vegetables. Utilized in the biomedical industry, it exhibits antioxidant and anti-inflammatory properties, making it a potential treatment for chronic diseases such as cardiovascular disorders and cancer. With its ability to scavenge free radicals and modulate cellular signaling pathways, this compound holds promise for therapeutic interventions. Synonyms: Cyanidin-3-o-rhamnoside chloride; Cyanidin 3-rhamnoside; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)chromenylium chloride; (2S,3R,4R,5R,6S)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromenylium-3-yl]oxy-6-methyloxane-3,4,5-triol; chloride; AKOS030524316; 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}-1-chromen-1-ylium chloride. CAS No. 38533-30-1. Molecular formula: C21H21O10Cl. Mole weight: 468.84. | |
| Cyanidin-3-O-sambubioside chloride | Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride), a major anthocyanin, a natural colorant, and is a potent NO inhibitor. Cyanidin 3-sambubioside chloride is a H274Y mutation inhibitor, and inhibits influenza neuraminidase activity with an IC50 of 72 μM. Cyanidin 3-sambubioside chloride inhibits angiotensin-converting enzyme (ACE) activity and has antioxidant, anti-angiogenic and antiviral properties. Synonyms: 33012-73-6|Cyanidin-3-O-sambubioside chloride|UNII-4BIT5WSL15|4BIT5WSL15|CYANIDIN-3-SAMBUBIOSIDE|Cyanidin 3-sambubioside (chloride)|Cyanidin 3-sambubioside|(2S,3R,4S,5R)-2-[(2S,3R,4S,5S,6R)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromenylium-3-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;chloride|cyanidin-3-O-sambubioside|3-(((2S,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromenylium chloride|cyanidin 3-O- (2-O-xylopyranosylglycopyranoside) |cyanidin 3-sambubioside chloride|HY-N2533|3,5,7,3',4'-Pentahydroxyflavylium-3-O-beta-D-xylopyranosyl-(1-2)-beta-D-glucopyranoside|CS-0022804|Q9333097|1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-((2-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl)oxy)-, chloride. Grades: >98%. CAS No. 33012-73-6. Molecular formula: C26H29O15Cl. Mole weight: 616.95. | |
| Cyanidin-3-O-sophoroside chloride | Cyanidin-3-O-sophoroside chloride is an antioxidant and anti-inflammatory compound used in studying afflictions associated with oxidative stress. Synonyms: 2-(3,4-Dihydroxyphenyl)-3-[(2-O-b-D-glucopyranosyl-a-D-glucopyranosyl)oxy]-5,7-dihydroxy-1-benzopyrylium chloride. CAS No. 38820-68-7. Molecular formula: C27H31O16Cl. Mole weight: 646.98. | |
| Cyanomethyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside | Cyanomethyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside is a versatile compound used in biomedicine. It acts as a substrate analog for β-galactosidase enzyme assays, aiding in the detection and quantification of this enzyme. Additionally, it can be employed for the synthesis of various drugs targeting diseases related to galactosyltransferase enzymes. This compound's unique structure and reactivity make it an essential tool in biomedical research and drug development. Synonyms: Cyanomethyl 2,3,4,6-tetra-O-acetyl-1-thio-beta-D-galactopyranoside; MFCD00057536; (2R,3S,4S,5R,6S)-2-(Acetoxymethyl)-6-((cyanomethyl)thio)tetrahydro-2H-pyran-3,4,5-triyl triacetate; [(2R,3S,4S,5R,6S)-3,4,5-TRIS(ACETYLOXY)-6-[(CYANOMETHYL)SULFANYL]OXAN-2-YL]METHYL ACETATE; ZNQCXCWNORCJGV-CWVYHPPDSA-N; SCHEMBL1140693; Cyanomethyl 2,3,4,6-tetra-O-acetyl-b-D-thiogalactopyranoside; AKOS022179223; AS-72153; CS-0205233; E86931; W-203283; Cyanomethyl2,3,4,6-tetra-O-acetyl-|A-D-thiogalactopyranoside; Cyanomethyl 2,3,4,6-Tetra-O-acetyl-1-thio-ss-D-galactopyranoside; (2R,3S,4S,5R,6S)-2-(acetoxymethyl)-6-(cyanomethylthio)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 61145-33-3. Molecular formula: C16H21NO9S. Mole weight: 403.41. | |
| Cyanomethyl 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside | Cyanomethyl 2,3,4,6-tetra-O-acetyl-b-D-thioglucopyranoside is a fascinating biochemical compound, intricately weaves glycosides and glycoconjugates. Remarkably, its distinctive structure catapults it into the forefront of drug discovery, particularly augmenting the pursuit of carbohydrate-based therapeutics designed to study afflictions ranging from cancer to diabetes and even perennial viral infections. Molecular formula: C16H21NO9S. Mole weight: 403.41. | |
| Cyanomethyl 2,3-O-isopropylidene-5-O-trityl-D-ribofuranoside | Cyanomethyl 2,3-O-isopropylidene-5-O-trityl-D-ribofuranoside is an essential compound employed in the realm of biomedical research, holding significant utility in the research and development of nucleoside analogs and antiviral compounds. Its pivotal role as an intermediate substance plays a vital part in the development of remedies designed to study pernicious viral infections. Molecular formula: C29H29NO5. Mole weight: 471.54. | |
| Cyclizine Dihydrochloride | Cyclizine 2HCl is a piperazine derivative with Histamine H1 receptor antagonist activity. Synonyms: Cyclizine 2HCl; Piperazine, 1-diphenylmethyl-4-methyl-, dihydrochloride. Grades: >98%. CAS No. 5897-18-7. Molecular formula: C18H24Cl2N2. Mole weight: 339.30. | |
| Cyclohexyl b-D-glucopyranoside | Cyclohexyl b-D-glucopyranoside is a pivotal biochemical compound abundantly employed within the biomedical sector, exhibiting inhibitory efficacy in studying diverse ailments and afflictions. Its applications encompass the drug development targeting diabetes, inflammation and neurological disorders. | |
| Cysmethynil | Cysmethynil is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT) with antitumor activity in cancer cells. Cysmethynil treatment results in inhibition of cell growth in an Icmt-dependent fashion, demonstrating mechanism-based activity of the compound. Treatment of cancer cells with cysmethynil results in mislocalization of Ras and impaired epidermal growth factor signaling. In a human colon cancer cell line, cysmethynil treatment blocks anchorage-independent growth, and this effect is reversed by overexpression of Icmt. Synonyms: 2-(1-octyl-5-m-tolyl-1H-indol-3-yl)acetamide; 1H-Indole-3-acetamide, 5-(3-methylphenyl)-1-octyl-. CAS No. 851636-83-4. Molecular formula: C25H32N2O. Mole weight: 376.54. | |
| Cys-spacer-Gly-Gly-Tyr-D-Thr-Gly-Phe-Leu-Ser(glucoside)-amide | | |
| D-[1-13C]Galacturonic acid potassium salt | | |
| D-3263 | D-3263 is a TRPM8 agonist ( transient receptor potential melastatin member 8) with potential antineoplastic activity. The active ingredient in enteric-coated TRPM8 agonist D-3263 hydrochloride binds to and activates TRPM8, which may result in an increase in calcium and sodium entry; the disruption of calcium and sodium homeostasis; and the induction of cell death in TRPM8-expressing tumor cells. This agent may decrease dihydrotestosterone (DHT) levels, which may contribute to its inhibitory effects on prostate cancer and BPH. TRPM8 is a transmembrane calcium channel protein that is normally expressed in prostate cells and appears to be overexpressed in benign prostatic hyperplasia (BPH) and in prostate cancer. Synonyms: 3-(2-Aminoethyl)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexanecarbonyl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one; 2H-Benzimidazol-2-one, 3-(2-aminoethyl)-1,3-dihydro-5-methoxy-1-(((1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl)carbonyl)-; 3-(2-Aminoethyl)-1-{[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl]carbonyl}-5-methoxy-1,3-dihydro-2H-benzimidazol-2-one. Grades: ≥95%. CAS No. 947257-66-1. Molecular formula: C21H31N3O3. Mole weight: 373.49. | |
| D4476 | D4476 is a potent, selective ATP-competitive inhibitor of CK1 (casein kinase 1). Synonyms: Casein Kinase I Inhibitor; D 4476; D-4476. Grades: >98%. CAS No. 301836-43-1. Molecular formula: C23H18N4O3. Mole weight: 398.41. | |
| d5-Ethyl b-D-glucuronide | d5-Ethyl b-D-glucuronide is a paramount and unparalleled biochemical compound, diligently employed within the biomedical industry as a powerful tool to delve into the intricate realm of drug metabolism and pharmacokinetics. This intriguing compound assumes the role of a remarkably stable isotope-labeled internal standard, flawlessly navigating the labyrinthine glucuronidation pathways. Synonyms: d5-Ethyl-b-D-6-glucuronide. Molecular formula: C8H9D5O7. Mole weight: 227.22. | |
| Dabigatran 2-Acyl Glucuronide-D3 | | |
| Dabigatran 3-acyl glucuronide | | |
| Dabigatran 4-Acyl Glucuronide | | |
| Dafadine-A | Dafadine-A, the first identified chemical inhibitor of DAF-9, could restrain the dauer formation, developmental timing and longevity in the nematodeCaenorhabditis elegans. Uses: Dafadine-a could restrain the dauer formation, developmental timing and longevity in the nematodecaenorhabditis elegans. Synonyms: Dafadine-A; CHEBI:88327; 1065506-69-5; Ambcb24199950; MLS001090772; CHEMBL1585869. Grades: 98%. CAS No. 1065506-69-5. Molecular formula: C23H25N3O3. Mole weight: 391.46. | |
| Daidzein 7-O-b-D-glucuronide potassium salt | Daidzein 7-O-b-D-glucuronide potassium salt is a heralded pharmaceutical compound exhibiting multifaceted attributes encompassing potential antioxidant prowess alongside unparalleled anti-inflammatory properties. Synonyms: 3-(4-Hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl b-D-Glucopyranosiduronic acid potassium salt. Molecular formula: C21H18O10. Mole weight: 430.36. | |
| D-Allono-1,4-lactone | D-Allono-1,4-lactone is a pivotal precursor in the ascorbic acid (vitamin C) synthesis processes, finding extensive utilization in research of vitamin C inadequacy, scurvy and affiliated ailments. Synonyms: D-Allonic acid gamma-lactone. CAS No. 29474-78-0. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| D-Allose-6-phosphate disodium salt hydrate | D-Allose-6-phosphate disodium salt hydrate, a dynamic biomedical substance, is renowned for its efficaciousness in combating specific ailments. Serving as a formidable hindrance to glucokinase, a multifaceted enzyme entangled in numerous metabolic maladies such as type 2 diabetes, this compound boasts an unrivaled chemical configuration that intricately modulates glucose metabolism. Synonyms: 6-O-[Hydroxy(oxo)phosphaniumyl]-D-allose; D-Allose,6-(dihydrogen phosphate); hydroxy-oxo-[(2R,3R,4R,5R)-2,3,4,5-tetrahydroxy-6-oxohexoxy]phosphanium; DTXSID90849400; [(1R,4S)-4-HYDROXY-2-CYCLOPENTEN-1-YL]CARBAMICACID,1,1-DIMETHYLETHYLESTER. CAS No. 82259-50-5. Molecular formula: C6H11O9PNa2. Mole weight: 304.10. | |
| D-Allulose (D-Psicose) | A C3 epimer of L-Fructose. Synonyms: D-Allulose; D-Ribo-2-hexulose. Grades: > 95%. CAS No. 551-68-8. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| D-Altrose | D-Altrose is a revered compound, emerging as a promising ally in studying diverse bacterial infections. Demonstrating its multifunctional attributes, it not only serves as a pivotal antibiotic precursor, stimulating their synthesis, but also augments their effectiveness. Moreover, the remarkable inhibitory prowess of D-Altrose against specific pathogenic bacteria endows it with unrivaled potential in studying the menacing antibiotic-resistant strains. Synonyms: (2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexanal; D(+)-Altrose; 5PLN1O36FF; Altrose, D-; 41846-94-0; UNII-5PLN1O36FF; NSC-2573; aldehydo-D-altrose; EINECS 217-870-4; D-ALRTOSE; D-ALTROSE [MI]; ALTROSE, (+)-; SCHEMBL15894565; DTXSID10894871; GZCGUPFRVQAUEE-ARQDHWQXSA-N; NSC 2573; GEO-00058; AKOS027320138; HY-W145652; CS-0226081; Q423207; 5987-68-8. CAS No. 1990-29-0. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| Daniquidone | Daniquidone, also known as Batracylin, is a water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of daniquidone is highly toxic and is capable of inducing unscheduled DNA synthesis; rapid acetylators are more likely to experience toxicity with this agent. Synonyms: Batracylin; Bay H 2049; NSC-320846; 8-Aminoisoindolo[1,2-b]quinazolin-12(10H)-one. CAS No. 67199-66-0. Molecular formula: C15H11N3O. Mole weight: 249.27. | |
| D-Apiose - Aqueous solution | D-Apiose - Aqueous solution is an aqueous solution, instrumental in antiviral drug synthesis. D-Apiose is used to study diverse viral ailments. Synonyms: 3-C-(Hydroxymethyl)-D-glycero-tetrofuranose. CAS No. 639-97-4. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| Dapitant | Dapitant, also known as RPR100893, is a potent and selective NK1 receptor antagonist both in vitro and in vivo, and exhibits high affinity for guinea pig and human NK1 receptor.Dapitant was developed as a potential drug for the acute treatment of migraine. However, in clinical trials, it was not effective. Synonyms: RPR100893; RPR 100893; RPR-100893; Erispant; (S)-1-((3aS,4S,7aS)-4-hydroxy-4-(2-methoxyphenyl)-7,7-diphenylhexahydro-1H-isoindol-2(3H)-yl)-2-(2-methoxyphenyl)propan-1-one. CAS No. 153438-49-4. Molecular formula: C37H39NO4. Mole weight: 561.72. | |
| D-Arabinaric acid dipotassium salt | Cas No. 6703-5-5. | |
| D-Arabino-1,4-lactone | D-Arabino-1,4-lactone is a prominent and intriguing natural compound with profound antioxidant capabilities and profound antitumor attributes. Synonyms: D-Arabonolactone; D-Arabinono-1,4-lactone; 1,4-D-Arabinonolactone; D-Arabonic acid 1,4-lactone; D-Arabinonic acid, gamma-lactone; (3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)dihydro-2(3H)-furanone. Grades: ≥95%. CAS No. 42417-44-7. Molecular formula: C5H8O5. Mole weight: 148.11. | |
| D-Arabino-5-hexulosonic acid | D-Arabino-5-hexulosonic acid is an imperative compound used in research of metabolic disorders, diabetes, cardiovascular ailments and neurodegenerative disorders. Synonyms: D-Tagaturonic acid; 5-Keto-L-galactonic acid. CAS No. 6812-1-7. Molecular formula: C6H10O7. Mole weight: 194.14. | |
| D-Arabinopyranosyl thiosemicarbazide | D-Arabinopyranosyl thiosemicarbazide is an esteemed biomedical product with its remarkable antiviral properties. This compound exhibits promising inhibition in studying notorious viral assailants like dengue and Zika. Synonyms: D-Arabinose (aminothioxomethyl)hydrazone; N-D-arabinopyranosyl-hydrazinecarbothioamide. CAS No. 262849-62-7. Molecular formula: C6H13N3O4S. Mole weight: 223.25. | |
| D-Arabinose-5-phosphate | D-Arabinose-5-phosphate is a crucial biochemical compound widely utilized in biomedicine. It plays a vital role in the synthesis of nucleotide sugars necessary for the production of glycoproteins and glycolipids. Synonyms: D-arabinose 5-phosphate; 13137-52-5; arabinose 5-phosphate; D-arabinose-5-phosphate; aldehydo-D-arabinose 5-phosphate; D-A-5-P; CHEBI:16241; [(2R,3R,4S)-2,3,4-trihydroxy-5-oxopentyl] dihydrogen phosphate; 5-O-phosphono-D-arabinose; D-arabinose, 5-(dihydrogen phosphate); arabinose-5P; arabinose-5-P; A5P; 1uj6; SCHEMBL939515; CHEMBL1162524; DTXSID90927171; D-arabinose 5-(dihydrogen phosphate); PD193841; C01112; Q27101812; {[(2R,3R,4S)-2,3,4-trihydroxy-5-oxopentyl]oxy}phosphonic acid. CAS No. 13137-52-5. Molecular formula: C5H11O8P. Mole weight: 230.11. | |
| D-Arabinose-5-phosphate disodium salt | D-Arabinose-5-phosphate disodium salt is a biomedically utilized compound, exhibiting promising attributes in the research of malignant neoplasms and metabolic disorders, namely cancer and diabetes. The incorporation of sodium salt configuration augments solubility and bioaccessibility, thus rendering it highly amenable for pharmaceutical endeavors. CAS No. 89927-09-3. Molecular formula: C5H9Na2O8P. Mole weight: 274.07. | |
| D-?Arabinose, (aminothioxomethyl)?hydrazone | D-Arabinose, (aminothioxomethyl)hydrazone, a biomedical substance renowned for its therapeutic applications in combating specific ailments, manifests noteworthy antitumor properties that have been rigorously investigated in the realm of cancer therapy. Synonyms: D-Arabinopyranosyl thiosemicarbazide; 154634-27-2; [[(3S,4R,5R)-3,4,5-trihydroxyoxan-2-yl]amino]thiourea; 262849-62-7; W-201392. CAS No. 154634-27-2. Molecular formula: C6H13N3O4S. Mole weight: 223.247. | |
| D-Arabinose diethyldithioacetal | D-Arabinose diethyldithioacetal is a compound used in biomedicine for various purposes. It has been found to possess potential antidiabetic properties by promoting glucose uptake. Additionally, studies suggest its role as a drug delivery agent for targeted therapies against certain types of cancers. This versatile compound shows promise for further research and development in the biomedical industry. Synonyms: Diethylmercaptal-D-arabinose; 1941-50-0; 5,5-bis(ethylsulfanyl)pentane-1,2,3,4-tetrol; D-Arabinose diethyl mercaptal; D-Ribose, diethyl dithioacetal; 7152-47-8; D-LYXOSE-DIETHYLDITHIOACETAL; 13263-74-6; D-Arabinose, diethyl mercaptal; Arabinose, diethyl mercaptal, D-; 43179-48-2; NSC 19774; d-Ribose diethylmercaptal; SCHEMBL3604543; IZQLWYVNJTUXNP-UHFFFAOYSA-N; NSC19655; NSC19774; NSC-19655; NSC-19774; NSC170213; AKOS003395567; NSC-170213; NCGC00337116-01; 5,5-bis(ethylthio)pentane-1,2,3,4-tetrol; AB01329659-02; 5,5-BIS(ETHYLSULFANYL)-1,2,3,4-PENTANETETRAOL. CAS No. 1941-50-0. Molecular formula: C9H20O4S2. Mole weight: 256.38. | |
| D-Arabonic acid | D-Arabonic Acid is a compound playing a pivotal role in the synthesis of distinguished anti-neoplastic compounds and antibiotics. CAS No. 13752-83-5. Molecular formula: C5H10O6. Mole weight: 166.13. | |
| Darinaparsin | Darinaparsin is a small-molecule organic arsenical with potential antineoplastic activity. Although the exact mechanism of action is unclear, darinaparsin, a highly toxic metabolic intermediate of inorganic arsenicals (iAs) that occurs in vivo, appears to generate volatile cytotoxic arsenic compounds when glutathione (GSH) concentrations are low. The arsenic compounds generated from darinaparsin disrupt mitochondrial bioenergetics, producing reactive oxygen species (ROS) and inducing ROS-mediated tumor cell apoptosis; in addition, this agent or its byproducts may initiate cell death by interrupting the G2/M phase of the cell cycle and may exhibit antiangiogenic effects. Compared to inorganic arsenic compounds such as arsenic trioxide (As2O3), darinaparsin appears to exhibit a wide therapeutic window. Synonyms: ZIO 101; ZIO101; ZIO-101; SP-02; SP 02; SP02; Zinapar; L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine. CAS No. 69819-86-9. Molecular formula: C12H22AsN3O6S. Mole weight: 411.31. | |
| Dasatinib Monohydrate | Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Uses: Antineoplastic agents. Synonyms: BMS-354825 Monohydrate; BMS 354825 Monohydrate; BMS354825 Monohydrate; N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate. Grades: >98%. CAS No. 863127-77-9. Molecular formula: C22H28ClN7O3S. Mole weight: 506.02. | |
| DAT-230 | DAT-230 is a promising microtubule inhibitor that has great potential for the treatment of fibrosarcoma in vitro and in vivo. DAT-230 exhibited potent anti-proliferative activity against various cancer cells. DAT-230-treatment in HT-1080 cells resulted in microtubule de-polymerization and G2/M phase arrest preceding apoptosis. Phosphor-cdc2 (thr14/tyr15) reduction, cyclin B1 accumulation and aberrant spindles denoted the cyclin B1-cdc2 complex active and M phase arrest in HT-1080 cells treated with DAT-230. Apoptosis induced by DAT-230 was related with the activation of caspase-9, caspase-3 and PARP cleavage, which were at the downstream of mitochondria. The decrease ratio of Bcl-2/Bax, elevation of NO and disruption of ΔΨm confirmed the causal relationship between DAT-230 and mitochondrial pathway. In vivo, DAT-230 delayed tumor growth, induced tumor perfusion decrease and extensive hemorrhagic-necrosis. Synonyms: DAT 230; DAT230. Grades: 98%. CAS No. 1504583-00-9. Molecular formula: C22H20BrN3O2S. Mole weight: 339.45. | |
| Datelliptium chloride | Datelliptium chloride, derived from ellipticine, is a DNA-intercalating agent with good activity in murine tumor models over a broad range of doses. Synonyms: 2-[2-(diethylamino)ethyl]-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-2-ium-9-ol;chloride; 2-(diethylamino-2-ethyl)-9-hydroxyellipticinium; 2-DEHE; datelliptium chloride; detalliptinium; detalliptinium acetate salt; detalliptinium chloride; detalliptium acetate; diethylaminoethyl-2-OH-9-ellipticinium; NSC 311152; NSC 626718X; NSC-311152; SR 95156A; SR 95156B; SR-95156A. CAS No. 105118-14-7. Molecular formula: C23H28ClN3O. Mole weight: 397.94. | |
| Daunomycin | Daunomycin is an intermediate of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 8-Acetyl-6,10,11-trihydroxy-1-methoxytetracene-5,12-dione; 8-Acetyl-5,12-dihydro-6,10,11-trihydroxy-1-methoxynaphthacene-5,12-dione; 5,12-Naphthacenedione, 8-acetyl-6,10,11-trihydroxy-1-methoxy-; Daunorubicin Impurity 5. Grades: ≥95%. CAS No. 20982-41-6. Molecular formula: C21H14O7. Mole weight: 378.33. | |
| Daunorubicin-d3 | Daunorubicin-d3 , a meticulously stable isotope-enriched rendition of Daunorubicin, is an esteemed anthracycline antibiotic extensively employed in the research of diverse cancer modalities, encompassing acute myeloid leukemia, lymphomas and solid tumors. Molecular formula: C27H26D3NO10. Mole weight: 530.54. | |
| Daunorubicinol-D3 | | |
| Daxdilimab | Daxdilimab is a human anti-ILT7 monoclonal antibody. Daxdilimab binds to ILT7 on the surface of pDCs, which leads to the depletion of these cells and inhibits inflammation in a variety of autoimmune conditions. Synonyms: MEDI7734; VIB7734; HZN-7734. CAS No. 2245966-28-1. | |
| DBZ | DBZ, also called dibenzazepine, is a γ-secretase inhibitor to treat Alzheimer's Disease, and it also inhibits Notch signaling. Synonyms: YO-01027; YO 01027; YO01027; (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide; dibenzazepine; GSI XX; Dibenzazepine; 209984-56-5; YO-01027; (S)-2-(2-(3,5-Difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide; Deshydroxy LY 411575; gamma-Secretase Inhibitor XX; DBZ; 209984-56-5 pound not YO 01027; (S,S)-2-[2-(3,5-Difluorophenyl)acetylamino]-N-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propionamide; N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide; C26H23F2N3O3; GSI-XX; g-secretase inhibitor XX; Gamma-secretase inhibitor; Deshydroxy LY-411514; Deshydroxy LY-411575; MLS006011073; SCHEMBL3046688; DTXSID6040458; AOB1375; ANW-62574; ZINC22056928; AKOS016004347; RL02593; YO01027; NCGC00263188-01; AC-27417; AJ-80844; AK101890; BC638679; SMR004676467; AB0033830; KB-210919; TC-151319; FT-0666470; ST24035862; X7602; Z-3141; (2S)-2-[2-(3,5-. Grades: >98%. CAS No. 209984-56-5. Molecular formula: C26H23F2N3O3. Mole weight: 463.48. | |
| DC-009 | DC-009 is a small-molecule thrombolytic that can scavenge the free radical in cells. Studies in vitro and in vivo showed that DC-009 had the similar activity as recombinant tissue plasminogen activator (rt-PA) and dose-dependent activity. Further study of treating ischemic stroke is planned. Uses: The potential treatment of ischemic stroke. Synonyms: DC009; DC 009. | |
| DC-05 | DC-05 is a potent and selective non-nucleoside DNMT1 (DNA methyltransferase 1) inhibitor with IC50 of 10.3 uM. It has significant selectivity toward other AdoMet-dependent protein methyltransferases. It significantly inhibits cancer cell proliferation. It inhibitis DNMT1 by binding to DNMT1 instead of incorporating into DNA. Uses: Dc-05 inhibits cancer cell proliferation. Synonyms: DC-05; DC 05; DC05; 1-Carbazol-9-yl-3-[2-(1H-indol-3-yl)ethylamino]propan-2-ol. Grades: >98 %. CAS No. 890643-16-0. Molecular formula: C25H25N3O. Mole weight: 383.49. | |
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