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Dilmapimod
Dilmapimod, also known as SB-681323, is p38 MAPK inhibitor. The treatment with SB-681832 is a safe and effective means of reducing hsCRP in patients undergoing elective PCI. Synonyms: Dilmapimod; SB-681323; SB 681323; SB681323; GW 681323; GW-681323; GW681323. Grades: 98%. CAS No. 444606-18-2. Molecular formula: C23H19F3N4O3. Mole weight: 456.42.
Diloxanide
Diloxanide is a luminal amebicide used in the treatment of amebiasis which is an infection of the diegestive tract caused by amoebas of the entamoeba group. It is considered the choice for asymptomatic cyst carriers. It is a second line treatment after paromomycin when no symptoms are present in places where infections are not common. Uses: Diloxanide is used in the treatment of amebiasis. Synonyms: 2,2-Dichloro-4'-hydroxy-N-methylacetanilide; Ame-boots; Amebamida; Dichloro-N-4-hydroxyphenyl-N-methylacetamide; Diloxanid; Entamide; N-Dichloroacetyl-N-methyl-p-hydroxyaniline; RD 3803. Grades: 98%. CAS No. 579-38-4. Molecular formula: C9H9Cl2NO2. Mole weight: 234.08.
DiMNF has been found to be a selective AHR modulator and could probably be useful in some inflammatory tumor cell microenvironment. Synonyms: 2-(3,4-Dimethoxyphenyl)-4H-naphtho[1,2-b]pyran-4-one. Grades: ≥99% by HPLC. CAS No. 14756-24-2. Molecular formula: C21H16O4. Mole weight: 332.35.
dinutuximab
Dinutuximab is an anti-GD2 monoclonal antibody. Dinutuximab beta was approved for the treatment of patients with high-risk neuroblastoma. In combination with interleukin-2, dinutuximab beta is used to treat those who have not achieved a complete response after first-line therapy. Uses: The treatment of patients with high-risk neuroblastoma. CAS No. 1363687-32-4. Molecular formula: C6422H9982N1722O2008S48. Mole weight: 145000.
Diosmetin-3,7-diglucuronide
Diosmetin-3,7-diglucuronide is an intriguing compound product, showcasing extraordinary efficacy in studying oxidative stress-related maladies owing to its exceptional antioxidant attributes. Synonyms: Diosmetin 3',7-Diglucuronide (>85per cent); (2S,3S,4S,5R,6R)-6-[2-[3-[(2R,3R,4S,5S,6S)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]oxy-4-(trideuteriomethoxy)phenyl]-5-hydroxy-4-oxochromen-7-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid. CAS No. 152503-51-0. Molecular formula: C28H28O18. Mole weight: 652.51.
Diosmetin-3-O-glucuronide
Diosmetin 3-O-β-D-Glucuronide is a metabolite of Diosmetin. Synonyms: (2S,3S,4S,5R,6S)-6-(5-(5,7-Dihydroxy-4-oxo-4Hc-chromen-2-yl)-2-methoxyphenoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. Grades: > 95%. CAS No. 152503-50-9. Molecular formula: C22H20O12. Mole weight: 476.39.
Dipivefrine
Dipivefrine is a prodrug of adrenaline and is used to treat glaucoma. It penetrates the cornea and is then hydrolysed to epinephrine by esterase enzymes. It increases outflow of the aqueous humour and reduces its formation, thus reducing pressure inside the eye. It also increases the conductivity of trabecular filtering cells. It has been listed. Uses: Dipivefrine is used to treat glaucoma. Synonyms: Dipivefrinum; dipivalyl epinephrine; 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-phenylene bis(2,2-dimethylpropanoate). Grades: 98%. CAS No. 52365-63-6. Molecular formula: C19H29NO5. Mole weight: 351.44.
Dipyridamole di-O-b-D-glucuronide
Dipyridamole di-O-b-D-glucuronide is a prominent pharmaceutical compound , finding its specialized application in the research of cardiovascular afflictions. Synonyms: 2,2,2,2-[(4,8-Dipiperidinopyrimido[5,4]pyrimidine-2,6-diyl)dinitrilo]tetraethanol di-b-D-glucuronide. CAS No. 107136-95-8. Molecular formula: C36H56N8O16. Mole weight: 856.87.
Dipyridamole mono-O-b-D-glucuronide
Dipyridamole mono-O-b-D-glucuronide is a pharmaceutical compound used in the biomedical industry to study the metabolism and excretion of Dipyridamole. It is a glucuronide conjugate formed during the hepatic metabolism of Dipyridamole, an antiplatelet drug used to prevent blood clots in conditions like coronary artery disease and after heart valve replacement surgeries. Synonyms: 2-[[6-[Bis(2-hydroxyethyl)amino]-4,8-D-1-piperidinylpyrimido[5,4-D]pyrimidin-2-yl](2-hydroxyethyl)amino]ethyl b-D-glucopyranosiduronic acid. CAS No. 63912-02-7. Molecular formula: C30H48N8O10. Mole weight: 680.75.
Disodium Cromoglycate
Disodium Cromoglycate is an antiallergic drug with IC50 of 39 μg/mL. Uses: Mast cell stabilizers. Synonyms: FPL 670; FPL670; FPL-670. Grades: >98%. CAS No. 15826-37-6. Molecular formula: C23H14O11.2Na. Mole weight: 512.33.
DKM 2-93
DKM 2-93 covalently modify the catalytic cysteine of the ubiquitin-like modifier activating enzyme 5 (UBA5), thereby inhibiting its activity as a protein that activates the ubiquitin-like protein UFM1 to UFMylate proteins (IC50 = 430 μM). Synonyms: 2-chloro-N-[(3,4-dimethoxyphenyl)methyl]acetamide. CAS No. 65836-72-8. Molecular formula: C11H14ClNO3. Mole weight: 243.69.
DL-1,2-Isopropylideneglycerol
A MEK inhibitor with antitumor activity. Synonyms: (2,2-dimethyl-1,3-dioxolan-4-yl)methanol. Grades: 98%. CAS No. 100-79-8. Molecular formula: C6H12O3. Mole weight: 132.16.
DL-Arabinose is a fundamental constituent found abundantly in nature. Serving as an indispensable component in the creation of Xylose isomerase is an enzymatic catalyst facilitating the transformation of xylose into xylulose, it assumes a paramount role in studying diverse metabolic anomalies like diabetes and obesity. Synonyms: Arabinose; (±)-Arabinose; dl-Arabinose. Grades: ≥95%. CAS No. 147-81-9. Molecular formula: C5H10O5. Mole weight: 150.13.
DL-Glyceraldehyde 3-phosphate solution
Cas No. 591-59-3.
DL-TBOA
DL-TBOA is a competitive and non-transportable inhibitor of excitatory amino acid transporters (IC50 = 70, 6, and 6 μM for EAAT1, EAAT2 and EAAT3, respectively). DL-TBOA also inhibits EAAT4 and EAAT5 (Ki = 4.4 and 3.2 μM, respectively). DL-TBOA is a glutamate uptake inhibitor. Synonyms: DL-threo-β-Benzyloxyaspartic acid; (2S,3S)-2-amino-3-phenylmethoxybutanedioic acid. Grades: ≥98% by HPLC. CAS No. 205309-81-5. Molecular formula: C11H13NO5. Mole weight: 239.23.
DL-threo-PDMP hydrochloride
DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP: D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP inhibits glucosylceramide synthase by 33 and 48% in MDCK cell homogenates when used at concentrations of 5 and 10 μM. It reduces the synthesis of glucosylceramide, increases cellular ceramide, and induces cell cycle arrest in vitro. Synonyms: DL-PDMP; D,l-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol HCl; SMR000326846. Grades: ≥98%. CAS No. 80938-69-8. Molecular formula: C23H38N2O3·HCl. Mole weight: 427.
DL-threo-PPMP hydrochloride
DL-threo-PPMP is a ceramide analog that inhibits glucosylceramide synthase. It has been used to study the role of glucosylceramide synthase in cell growth, apoptosis, and autophagy. Synonyms: DL-threo-1-Phenyl-2-palmitoylamino-3-morpholino-1-propanol; DL-PPMP; BML3-D12; CTK8E7792. Grades: ≥98%. CAS No. 139974-41-7. Molecular formula: C29H50N2O3·HCl. Mole weight: 511.2.
DL-Xylose
DL-Xylose, a fundamental monosaccharide sugar renowned for its biomedical significance, has become a staple substrate in the identification and management of a host of diseases spanning diabetes, inflammatory bowel disease, and cardiovascular afflictions. This versatile sugar also serves as a preeminent precursor in the synthesis of several bioactive molecules, rendering it an indispensable constituent of the biomedicine domain. Owing to its exceptional qualities and applicability, DL-Xylose has emerged as a pivotal entity in cutting-edge biomedical research. CAS No. 41247-05-6. Molecular formula: C5H10O5. Mole weight: 150.13.
D-Lyxo-5-hexulosonic acid
D-Lyxo-5-hexulosonic acid presents itself as an indispensable compound within the biomedical realm is assuming a pivotal role in curative interventions for a diverse assortment of metabolic anomalies and ailments. Functioning as an indispensable precursor, it proficiently catalyzes the biosynthesis of indispensable entities including pentose sugars and ascorbic acid, both of which are inextricably linked to the sustenance of human well-being. By virtue of its far-reaching therapeutic potential, encompassing diseases such as diabetes, cardiovascular afflictions and neurological dysfunctions, this compound assumes a paramount stance in the expansive domain of compound. Synonyms: D-Fructuronic acid; D-Fructuronate; Fructuronic acid. CAS No. 13425-76-8. Molecular formula: C6H10O7. Mole weight: 194.14.
D-Lyxonic acid potassium salt
D-Lyxonic acid potassium salt is a fundamental constituent widely applied within the biomedical sphere, showcases its utilization encompasses the R&D of medicinal remedies for sundry afflictions. Synonyms: 2,3,4,5-Tetrahydroxy-pentanoic acid, potassium salt. CAS No. 78138-87-1. Molecular formula: C5H9KO6. Mole weight: 204.22.
D-Lyxono-1,4-lactone
D-Lyxono-1,4-lactone is a remarkable compound, acting as a quintessential catalyst. D-Lyxono-1,4-lactone orchestrates a pivotal role in intensifying pharmaceutical potency, thereby harbouring potential in studying intractable drug-resistant maladies. Synonyms: D-Lyxonic Acid γ-Lactone; (3S,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one; Lyxonic acid-1,4-lactone. Grades: ≥95%. CAS No. 15384-34-6. Molecular formula: C5H8O5. Mole weight: 148.11.
D-Lyxosylamine
D-Lyxosylamine, a fundamental compound in the biomedical field, emerges as an imperative catalyst for the amalgamation of a myriad of pharmaceuticals that aim to combat ailments like cancer, diabetes, and viral infections. Unmistakably, its quintessential role as a pivotal cornerstone in medicinal advancement augments the potency and efficacy of therapeutic solutions. With its unparalleled synthetic efficiency and multifaceted utility, D-Lyxosylamine assumes an integral stature within the realm of biomedical exploration and the quest for groundbreaking drug innovations. Synonyms: D-Lyxosylamine; 39840-37-4; (2S,3R,4R)-2-amino-3,4,6-trihydroxyhexanal; SCHEMBL17813108; 2-amino-2,5-dideoxy-D-lyxo-hexose; AKOS006273594; W-202637. CAS No. 39840-37-4. Molecular formula: C5H11NO4. Mole weight: 149.10.
D-Mannitol 1-phosphate lithium salt
D-Mannitol 1-phosphate lithium salt is a paramount compound extensively employed in the biomedical sector,used for the research of specific ailments, including diabetes and cancer. Synonyms: mannitol 1-phosphate; 15806-48-1; D-Mannitol 1-phosphate; mannitol-1-phosphate; D-mannitol-1-phosphate; [(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexoxy]phosphonic acid; mannitol-1-P; [(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl] dihydrogen phosphate; D-Mannitol, 1-(dihydrogen phosphate); 1-O-phosphono-D-mannitol; 44H; SCHEMBL428503; CHEBI:16298; D-mannitol 1-(dihydrogen phosphate); C00644; Q27101838; {[(2R,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl]oxy}phosphonic acid. CAS No. 15806-48-1. Molecular formula: C6H15O9P xLi. Mole weight: 262.15 (free acid basis).
D-Mannitol - EP
D-Mannitol - EP is a biomedical product commonly used for development of osmotic diuretic to study conditions such as increased intracranial pressure and cerebral edema. Molecular formula: C6H14O6. Mole weight: 182.17.
D-Mannoheptose
D-Mannoheptose is a chemical component of lipopolysaccharides (O antigens) allowing for antigenic properties. Synonyms: D-Glycero-D-galacto-heptose. CAS No. 7634-39-1. Molecular formula: C7H14O7. Mole weight: 210.18.
D-Mannoheptulose
D-Mannoheptulose is an intriguing sugar compound prevalent in diverse fruits. Drawing from its inherent properties, this enigmatic substance exhibits promising therapeutic possibilities for studying diabetes and obesity. The underlying mechanism is believed to involve the remarkable inhibition of key enzymes pivotal to the intricate realm of carbohydrate metabolism. Synonyms: D-Manno-2-heptulose. CAS No. 3615-44-9. Molecular formula: C7H14O7. Mole weight: 210.18.
D-Mannojirimycin hydrogensulfite
D-Mannojirimycin hydrogensulfite is a potent inhibitor exhibiting antiviral and antitumor activities, making it valuable in the development of drugs targeting specific viruses or tumors. Synonyms: 5-Amino-5-deoxy-D-mannopyranose hydrogensulfite. Molecular formula: C6H13NO7S. Mole weight: 243.24.
D-Mannonic acid-1,4-lactone
D-Mannonic acid-1,4-lactone is a vital pharmaceutical intermediate within the biomedical realm, emerging as a pivotal compound in the synthesis of various drugs and compounds. Its profound significance manifests in the research of urinary tract infections, respiratory afflictions and bacterial invasions. Synonyms: D-Mannono-1,4-lactone. CAS No. 26301-79-1. Molecular formula: C6H10O6. Mole weight: 178.14.
D-Mannopyranose pentasulfate potassium salt
D-Mannopyranose pentasulfate potassium salt, a biomedical marvel, unveils its prowess in combatting multifarious ailments. Its multifaceted nature encompasses its anti-inflammatory and anticoagulant attributes, rendering it indispensable in rectifying afflictions stemming from aberrant coagulation and inflammation. Synonyms: D-Mannopyranose pentasulfate potassium salt; pentapotassium; [(2R,3R,4S,5S)-3,4,5,6-tetrasulfonatooxyoxan-2-yl]methyl sulfate; D-Mannopyransepentasulfate Potassium salt; Potassium (3S,4S,5R,6R)-6-((sulfonatooxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetrakis(sulfate); D-Mannopyranse pentasulfate potassium salt. CAS No. 111757-61-0. Molecular formula: C6H7K5O21S5. Mole weight: 770.93.
D-Mannosaminuronic acid
D-Mannose-6-O-sulphate sodium salt
D-Mannose-6-O-sulphate sodium salt, an influential biomedical agent, exhibits remarkable efficacy against a spectrum of viral infections like herpes simplex and cytomegalovirus. With its ability to impede viral adhesion to host cells, it curtails viral proliferation effectively. Additionally, owing to its potent anti-inflammatory attributes, there lies a promising avenue for employing this compound in mitigating inflammatory ailments encompassing arthritis and asthma. Synonyms: Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl sulfate; sodium; [(2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl] sulfate; D-Mannose, 6-(hydrogen sulfate), monosodium salt (9CI); Sodium(2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexylsulfate; sodium (2S,3S,4R,5R)-2,3,4,5-tetrahydroxy-6-(sulfonatooxy)hexanal. CAS No. 204575-08-6. Molecular formula: C6H11O9SNa. Mole weight: 282.20.
D-Mannose-6-phosphate barium salt hydrate
D-Mannose-6-phosphate barium salt hydrate is a biomedically significant compound assuming a crucial position within the realm of glycosylation disorders, particularly in cases linked to phosphomannomutase 2 (PMM2) deficiency. CAS No. 104872-94-8. Molecular formula: C6H11BaO9P 2H2O. Mole weight: 395.45.
D-Mannose-6-phosphate disodium salt hydrate
D-Mannose-6-phosphate disodium salt hydrate, an indispensable compound within the biomedical sector, holds immense significance in addressing and overseeing a myriad of conditions such as diabetes, urinary tract infections, and glycogen storage diseases. Its pharmaceutical formulations benefit from the heightened stability and solubility imparted by this particular salt hydrate manifestation. Uses: Mannose-6-phosphate (m6p) is a molecule bound by lectin in the immune system. m6p is converted to fructose 6-phosphate by mannose phosphate isomerase. m6p is a key targeting signal for acid hydrolase precursor proteins that are destined for transport to lysosomes. Synonyms: Disodium D-mannose 6-phosphate;Sodium (2R,3R,4S,5S)-2,3,4,5-tetrahydroxy-6-oxohexyl phosphate; D-Mannose 6-phosphate disodium salt;mannose-6-phosphate disodium; d-Mannose, 6-(dihydrogen phosphate), disodium salt. CAS No. 33068-18-7. Molecular formula: C6H11O9PNa2 H2O. Mole weight: 322.11.
D-Mannose-6-phosphate sodium salt
D-Mannose-6-phosphate sodium salt is a vital compound assuming a pivotal function in the research of numerous ailments such as Diabetes Mellitus Type 2. Moreover, this sodium salt serves as a precursor in the biosynthesis of glycoproteins, integral to cellular communication and immunological responses. CAS No. 70442-25-0. Molecular formula: C6H12NaO9P. Mole weight: 282.12.
D-Mannose-BSA
D-Mannose - F
D-Mannose - F is a natural supplement used in biomedical field supporting the research of urinary tract infections by inhibiting bacterial adhesion to the bladder wall.
D-Mannose - F (from birch)
D-Mannose - F (from birch) is an intriguing and indispensable natural compound extracted from the illustrious birch, used for studying urinary tract infections (UTIs). Molecular formula: C6H12O6. Mole weight: 180.16.
D-Mannose Tablets
D-Mannose tablets is a remarkable biomedical compound, used for studying the pervasive urinary tract infections (UTIs). Capitalizing on the extraordinary properties of D-Mannose is an inherently existing saccharide, these tablets intricately obstruct bacterial binding to the urinary tract epithelium. Molecular formula: C6H12O6. Mole weight: 180.16.
D-Mannurono-6,3-lactone
D-Mannurono-6,3-lactone is an indispensable compound, acting as a precursor in vitamin C synthesis to augment collagen generation and facilitate the absorption of iron. Moreover is an exceptional attribute of D-Mannurono-6,3-lactone lies in its antioxidants capabilities, proficiently safeguarding cellular entities against the detrimental effects of oxidative burdens. P. Synonyms: D-Mannuronic acid lactone;D-Mannofuranuronic acid gamma-lactone. CAS No. 7424-9-1. Molecular formula: C6H8O6. Mole weight: 176.12.
DMAT
DMAT is a potent and specific CK2 inhibitor. It also displays submicromolar IC50 values with almost all of the other kinases with special reference to PKD1, PIM3 and PIM1. Synonyms: Casein kinase II Inhibitor; CK2 Inhibitor. Grades: >98%. CAS No. 749234-11-5. Molecular formula: C9H7Br4N3. Mole weight: 476.79.
DMH-1
DMH-1 is a second-generation small-molecule BMP inhibitor based on dorsomorphin. It effectively inhibits ALK1/2/3. It was shown to induce neuronal differentiation in human-induced pluripotent stem cells (hiPSCs). Synonyms: DMH 1; 4-[6-(4-propan-2-yloxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. Grades: >98%. CAS No. 1206711-16-1. Molecular formula: C24H20N4O. Mole weight: 380.44.
DMPEN
DMPEN, the active metabolite of penclomedine [3,5-dichloro-4,6-dimethoxy-2-(trichloromethyl)pyridine], is an alkylation agent, and was demonstrated to have potent antitumor activity. DMPEN went Phase I clinical trials during 2000s. Synonyms: 4-O-Demethylpenclomedine; 4-Demethylpenclomedine; 4-Dmpen; NSC-682691; 3,5-dichloro-2-methoxy-6-(trichloromethyl)pyridin-4-ol. CAS No. 176046-79-0. Molecular formula: C7H4Cl5NO2. Mole weight: 311.36.
D-muco-Inositol
D-muco-Inositol is a remarkable biomedical product, used in studying diverse ailments encompassing diabetes, metabolic disorders and oxidative stress. Uses: A growth factor in many plants and animals; used as a nutritional supplement; an isomer of glucose that has traditionally been considered to be a b vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. Synonyms: inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; 87-89-8; meso-Inositol; Neo-inositol; 643-12-9; D-chiro-Inositol; 1L-Chiro-inositol; D-(+)-chiro-Inositol; cis-Inositol; 488-59-5; 1D-Chiro-inositol; Myoinositol; Scyllitol; 6917-35-7;(1R,2S,3r,4R,5S,6r)-cyclohexane-1,2,3,4,5,6-hexol; (1R,2S,3s,4R,5S,6s)-cyclohexane-1,2,3,4,5,6-hexol; Inositol, United States Pharmacopeia (USP) Reference Standard; myo-Inositol, European Pharmacopoeia (EP) Reference Standard; 1,2,3,4,5,6-Cyclohexanehexol, (cis,cis,cis,trans,cis,trans)- #; 1,2,3,4,5,6-cyclohexanehexol, (1alpha, 2alpha, 3alpha, 4beta, 5alpha, 6beta); Inositol, Pharmaceutical Secondary Standard; Certified Reference Material; 1.ALPHA., 2.ALPHA., 3.BETA., 4.ALPHA., 5.BETA., 6.BETA.-CYCLOHEXANEHEXOL; 2H3; myo-Inositol, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture. CAS No. 41546-34-3. Molecular formula: C6H12O6. Mole weight: 180.16.
D-myo-Inositol 1,2,3-triphosphate
D-myo-Inositol 1,2,3-triphosphate is an indispensable biomolecular entity, exhibiting its significance as a paramount signaling molecule. Its essentiality derives from its pivotal participation in the intricate process of intracellular calcium release, thereby facilitating various physiological phenomena encompassing neurotransmission and muscular contraction. Synonyms: Ins(1,2,3)P3. CAS No. 41613-02-9. Molecular formula: C6H15O15P3. Mole weight: 420.10.
D-myo-Inositol-1,2,5,6-tetraphosphate sodium salt
Cas No. 6917-35-7.
D-myo-Inositol-1,2,6-triphosphate sodium salt
D-myo-Inositol-1,2,6-triphosphate sodium salt is an eminent compound assuming the significant function of a secondary messenger molecule, concentrating solely on cellular signal transduction pathways. Exercising crucial control over intracellular calcium levels, this compound ultimately governs a myriad of cellular processes. Synonyms: 1,2,6-IP3. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-Myo-inositol-1,3,4,5-tetraphosphate ammonium salt
D-Myo-inositol-1,3,4,5-tetraphosphate ammonium salt is a potent bioactive compound with profound impact on intracellular calcium homeostasis, thereby rendering it a promising candidate for studying maladies encompassing neurodegeneration, cardiovascular afflictions and oncogenic processes. Synonyms: D-myo-Inositol-1,3,4,5-tetrakis(dihydrogen phosphate), Ammonium Salt (1:4); rac-(1R,2R,3S,4R,5R,6R)-4,6-Dihydroxycyclohexane-1,2,3,5-tetrayl tetrakis(dihydrogen phosphate), Tetraammonia Salt; (1R,2S,3S,4S,5S,6S)-4,6-Dihydroxy-1,2,3,5-cyclohexanetetrayl tetrakis[dihydrogen (phosphate)] ammoniate (1:4). Grades: >99%. CAS No. 1246355-68-9. Molecular formula: C6H28N4O18P4. Mole weight: 568.20.
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt is formed by the phosphorylation of Ins(1,4,5)P4 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)P4 acts in conjunction with IP3 to mobilize intracellular calcium. Synonyms: D-myo-Inositol-1,3,4,5-tetrakis(phosphate) octasodium salt; Ins(1,3,4,5)P4 sodium salt. CAS No. 210488-61-2. Molecular formula: C6H8Na8O18P4. Mole weight: 675.93.
D-myo-Inositol-1,3,4-triphosphate
D-myo-Inositol-1,3,4-triphosphate is a pivotal signaling molecule orchestratingand modulating an array of cellular functions, ranging from neurotransmitter liberation to the orchestration of muscular contracts and extends its impact even towards the delicate domain of immune responses. CAS No. 140385-74-6. Molecular formula: C6H12O15P3. Mole weight: 417.07.
D-Myo-inositol-1,3,5-triphosphate ammonium salt
D-Myo-inositol-1,3,5-triphosphate ammonium salt is a prominent compound, possessing immense significance as a pivotal cellular messenger in signal transduction pathways. This product finds substantial utility in the realm of studying calcium signaling, cellular metabolism and the regulation of cellular functions. Synonyms: myo-Inositol-1,3,5-tris(dihydrogen phosphate), Ammonium Salt (1:3); (1R,2S,3r,4R,5S,6s)-2,4,6-Trihydroxycyclohexane-1,3,5-triyl tris(dihydrogen phosphate), Triammonia Salt; IP3(1,3,5); (1R,2S,3r,4R,5S,6s)-2,4,6-Trihydroxy-1,3,5-cyclohexanetriyl tris[dihydrogen (phosphate)] triammoniate; 1,2,3,4,5,6-Cyclohexanehexol, 1,3,5-tris(dihydrogen phosphate), triammonium salt, (1α, 2α, 3α, 4β, 5α, 6β)-. Grades: >99%. CAS No. 1246355-67-8. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
D-myo-Inositol-1,3,5-triphosphate sodium salt
D-myo-Inositol-1,3,5-triphosphate sodium salt is an indispensable biomedical commodity extensively employed in research and pharmaceutical domains, serving as a vital second messenger in diverse cellular processes, thereby promoting intracellular calcium signaling. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-1,3,6-triphosphate
D-myo-Inositol-1,3,6-triphosphate is a fundamental bioactive compound extensively utilized in the realm of intracellular calcium pathways, fostering the research of intricate cellular functions encompassing neurotransmitter emancipation, endocrine exudation and even the orchestration of musculature. Molecular formula: C6H15O15P3. Mole weight: 420.10.
D-myo-Inositol 1,4,5,6-tetraphosphate sodium salt
D-myo-Inositol 1,4,5,6-tetraphosphate sodium salt, known for its significance in the biomedical field, emerges as an indispensable compound governing intricate cellular mechanisms and intercellular signal transduction cascades. Synonyms: D-myo-Inositol 1,4,5,6-tetrakis(dihydrogen phosphate) tetrasodium salt; 1,4,5,6-IP4 sodium salt; Tetrasodium (1R,2S,3S,4R,5R,6S)-5,6-dihydroxy-1,2,3,4-cyclohexanetetrayl tetrakis[hydrogen (phosphate)]; 1,2,3,4,5,6-Cyclohexanehexol, 1,2,3,4-tetrakis(dihydrogen phosphate), sodium salt, (1R,2S,3S,4R,5R,6S)- (1:4). Grades: ≥98%. CAS No. 157542-47-7. Molecular formula: C6H12Na4O18P4. Mole weight: 588.00.
D-Myo-inositol-1,4,5-triphosphate ammonium salt
D-Myo-inositol-1,4,5-triphosphate ammonium salt is a highly sought-after compound, manifesting as an instrumental entity in the intricate web of signal transduction pathways by functioning as a second messenger. Its paramount role lies in meticulously orchestrating calcium levels within cellular confines. Synonyms: D-myo-Inositol-1,4,5-tris(dihydrogen phosphate) Triammonium Salt;_x000B_rac-(1R,2R,3S,4R,5R,6S)-3,5,6-Trihydroxycyclohexane-1,2,4-triyl tris(dihydrogen phosphate), Triammonia Salt; (1R,2R,3S,4R,5R,6S)-3,5,6-Trihydroxy-1,2,4-cyclohexanetriyl tris[dihydrogen (phosphate)] triammoniate; IP3(1,4,5). Grades: >99%. CAS No. 345958-55-6. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
D-myo-Inositol 1,4,5-triphosphate potassium salt
D-myo-Inositol 1,4,5-triphosphate potassium salt is a paramount compound, finding extensive utility in the research of cellular signaling pathways. Serving as an inositol derivative, this product assumes the onerous responsibility of an efficacious second messenger for a myriad of intracellular phenomena. Unleashing its potential to mobilize calcium from intraorganic repositories, it assumes a critical function in the realm of neurotransmission investigation, cellular expansion and intricate proliferation exploration. Synonyms: d-Myo-inositol-1,4,5-trisphosphate tripotassium salt; D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt; hexapotassium; [(1R,2S,3R,4R,5S,6R)-2,3,5-trihydroxy-4,6-diphosphonatooxycyclohexyl] phosphate; Ins(1,4,5)-P3 hexapotassium salt; Ins(1,4,5)-P3 hexapotassium salt; 1,4,5-IP3 hexapotassium salt; 1,4,5-Ip3,hexapotassium salt; AKOS024456627; D-Myo-inositol 1,4,5-trisphosphate,hexapotassium salt; D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt; potassium (1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxycyclohexane-1,2,4-triyl triphosphate. CAS No. 103476-24-0. Molecular formula: C6H9K6O15P3. Mole weight: 648.64.
D-myo-Inositol 1,4,5-triphosphate sodium salt
D-myo-Inositol 1,4,5-triphosphate sodium salt is an imperative secondary messenger with pivotal involvement in numerous cell signaling pathways, this product exerts regulation over intracellular calcium levels. Its extensive research has revealed its significant contribution towards studying disorders associated with calcium imbalance, including neurodegenerative diseases, diabetes and cancer. CAS No. 27121-73-9. Molecular formula: C6H9Na6O15P3. Mole weight: 551.99.
D-myo-Inositol 1,4,6-triphosphate sodium salt
D-myo-Inositol 1,4,6-triphosphate sodium salt is an extensively refined chemical compound employed in the biomedical sector assuming the role of an intracellular messenger, orchestrating intricate cellular processes, namely, cell growth and calcium signaling. It manifests pivotal significance in the research of maladies associated with the dysregulation of inositol phosphate pathways, encompassing select cancers, neurodegenerative disorders and metabolic irregularities. Synonyms: Ins(1,4,6)-P3 (sodium salt); 1,4,6-IP3 (sodium salt). CAS No. 157380-18-2. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-1,5,6-triphosphate sodium salt
D-myo-Inositol-1,5,6-triphosphate sodium salt is a fundamental compound prominently employed sector assuming an indispensable character within cellular signal transduction pathways, orchestrating sundry physiological processes. This prodigious entity operates as a secondary courier is adroitly overseeing calcium levels and intricately modulating multifarious cellular functionalities. Synonyms: 1,5,6-IP3 sodium salt; Ins(1,5,6)-P3 sodium salt. CAS No. 120965-76-6. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-2,3-O-cyclohexylidene
D-myo-Inositol-2,3-O-cyclohexylidene exhibits inhibitory efficacy in studyting a myriad of ailments such as diabetes, polycystic ovary syndrome (PCOS) and metabolic irregularities. Synonyms: hexahydrospiro[1,3-benzodioxole-2,1'-cyclohexane]-4,5,6,7-tetrol; D-myo-Inositol-2,3-O-cyclohexylidene; 22144-55-4; 57029-87-5; Hexahydrospiro[benzo[d][1,3]dioxole-2,1'-cyclohexane]-4,5,6,7-tetraol; NSC156930; spiro[3a,4,5,6,7,7a-hexahydro-1,3-benzodioxole-2,1'-cyclohexane]-4,5,6,7-tetrol; DTXSID40944792; AKOS025117221; NSC-156930; FT-0665353; AQ-364/41885122; spiro(2,4-dioxabicyclo[4.3.0]nonane-3,1'-cyclohexane)-6,7,8,9-tetrol. CAS No. 57029-87-5. Molecular formula: C12H20O6. Mole weight: 260.28.
D-myo-Inositol-3,4,5-triphosphate
D-myo-Inositol-3,4,5-triphosphate is an indispensable molecule in the biomedical field, serving as a pivotal second messenger within intracellular signaling pathways, imposing control over calcium homeostasand intricate cellular mechanisms. Its significance lies in orchestrating critical processes, encompassing cellular proliferation, specialization and programmed cell death. The utilization of D-myo-Inositol-3,4,5-triphosphate prevails prominently in research endeavors and pharmaceutical advancements, with a primary focus on comprehending signal transduction, unraveling the complexities of neoplastic disorders and exploring promising therapeutic modalities. Synonyms: Ins(3,4,5)-P3; 3,4,5-IP4. Molecular formula: C6H12O15P3. Mole weight: 417.07.
D-myo-inositol 3-phosphate
D-myo-inositol 3-phosphate is an essential molecular compound extensively utilized in the research of diverse afflictions including the likes of Alzheimer's disease, depression and diabetes. Synonyms: Inositol 3-phosphate; 1D-myo-inositol 3-phosphate; D-myo-inositol 3-phosphate; L-myo-inositol 1-phosphate; 1L-myo-inositol 1-phosphate; D-myo-Inositol 3-monophosphate; 1D-myo-inositol 3-monophosphate; Inositol 3-monophosphate; myo-Inositol 3-phosphate; myo-Inositol 3-monophosphate; 2831-74-5; Myoinositol 3-phosphate; [(2S,3R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl] dihydrogen phosphate; myo-Inositol-1-phosphate; LIP; SCHEMBL7538; Inositol-1-phosphate, myo-; GTPL5204; SCHEMBL9094343; CHEBI:18169; DTXSID801311864; 1L-myo-inositol 1-(dihydrogen phosphate); C04006; Q27078075; 2BBBF2DA-0914-425A-B8C3-DA6A72567B32; { [ (2S, 3R, 5S, 6S) -2, 3, 4, 5, 6-pentahydroxycyclohexyl] oxy}phosphonic acid. CAS No. 2831-74-5. Molecular formula: C6H13O9P. Mole weight: 260.14.
DNA-PK Inhibitor IV
DNA-PK inhibitor IV is an inhibitor of DNA-dependent protein kinase (DNA-PK). It also inhibits the phosphatidylinositol 3-kinase (PI3K) isoforms p110β, p110δ, and p110γ but not p110α or class II PI3Ks, PI4Kβ, ATM, ATR, mTOR, CK2, or GRK2. Synonyms: 2-hydroxy-4-(4-morpholinyl)-benzaldehyde. Grades: ≥98%. CAS No. 70362-07-1. Molecular formula: C11H13NO3. Mole weight: 207.23.
(-)-D-Noviose
(-)-D-Noviose, a carbohydrate derivative, possesses promising therapeutic implications in the management of metabolic ailments and microbial infections. It has been established that (-)-D-Noviose manifests inhibitory tendencies towards bacterial enzymes implicated in peptidoglycan biogenesis, vital for bacterial cell wall maintenance. Furthermore, researchers have explored the applicability of (-)-D-Noviose as a putative glycosylation inhibitor in recombinant protein production, opening new avenues for biopharmaceutical research. Synonyms: 6-Deoxy-5-C-methyl-4-O-methyl-D-lyxo-hexose. CAS No. 206185-18-4. Molecular formula: C8H16O5. Mole weight: 192.21.
Dodecyl a-D-thiomannopyranoside
Dodecyl α-D-thiomannopyranoside is a biochemical product acting as a nonionic detergent to solubilize membrane proteins, facilitating their isolation and characterization. This compound finds applications in the study of various cellular processes and interactions, including membrane receptor functions, signal transduction pathways and enzyme activities. Its versatile nature makes it a valuable tool for investigating drug targets and disease mechanisms. Molecular formula: C18H36O5S. Mole weight: 364.54.
Doramapimod
Doramapimod (BIRB 796) is a member of the N-pyrazole-N'-naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB-796 has entered clinical trials for the treatment of autoimmune diseases. Synonyms: Urea, N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]-; N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea; Birb 796; BIRB 796BS; BRB 796; UNC 10225354; UNC10225354; 1-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea. Grades: >98%. CAS No. 285983-48-4. Molecular formula: C31H37N5O3. Mole weight: 527.66.
Dovitinib Dilactic Acid
Dovitinib is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Synonyms: Dovitinib Dilactic acid; TKI258 Dilactic acid; CHIR-258; CHIR 258; CHIR258; TKI258; TKI 258; TKI-258. Grades: >98%. CAS No. 852433-84-2. Molecular formula: C27H33FN6O7. Mole weight: 572.59.
Dovitinib Lactate Hydrate
Dovitinib lactate hydrate is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively. Synonyms: TKI258 lactate hydrate; CHIR-258 lactate hydrate; 4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydrate; Propanoic acid, 2-hydroxy-, compd. with 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone, hydrate (1:1:1). Grades: >98%. CAS No. 915769-50-5. Molecular formula: C24H29FN6O5. Mole weight: 500.52.