BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Ethyl 4,6-O-benzylidene-2-O-levulinoyl-b-D-thioglucopyranoside | Ethyl 4,6-O-benzylidene-2-O-levulinoyl-b-D-thioglucopyranoside is a paramount compound serving as an indispensable intermediary in the fabrication of prospective anti-neoplastic compounds. Molecular formula: C20H26O7S. Mole weight: 410.48. |  |
| Ethyl 4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-thioglucopyranoside | Ethyl 4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-thioglucopyranoside is a key biochemical compound with significant biomedical applications, intricately participating in the synthesis of groundbreaking pharmaceuticals. Molecular formula: C26H40O7SSi. Mole weight: 524.74. | |
| Ethyl 4,6-O-benzylidene-b-D-galactopyranoside | Ethyl 4,6-O-benzylidene-b-D-galactopyranoside, a renowned compound within the biomedical industry, proves to be highly advantageous in drug development for multiple ailments such as cancer and neurological disorders. Encouraging research has showcased its efficacy as a potential therapeutic agent, effectively impeding the growth and proliferation of tumor cells in specific cancer types. CAS No. 101833-22-1. Molecular formula: C15H20O6. Mole weight: 296.32. | |
| Ethyl 4,6-O-benzylidene-b-D-thiogalactopyranoside | Ethyl 4,6-O-benzylidene-b-D-thiogalactopyranoside, a pivotal compound in the realm of biomedical research, assumes an indispensable role in unraveling intricate molecular interactions and functions linked to proteins implicated in an array of ailments, including cancer and metabolic disorders. With its profound implications in the realm of drug-target interactions, therapeutic mechanisms, and potential interventions, this compound emerges as an invaluable asset for discerning disease pathways and driving drug discovery efforts, thus bestowing unparalleled significance upon the field of biomedicine. Synonyms: Ethyl 4,6-O-benzylidene-1-thio-b-D-galactopyranoside. CAS No. 56119-28-9. Molecular formula: C15H20O5S. Mole weight: 312.39. | |
| Ethyl 4,6-O-benzylidene-b-D-thioglucopyranoside | Ethyl 4,6-O-benzylidene-b-D-thioglucopyranoside, an indispensable entity in the realm of biomedicine, holds immense significance for its role in the synthesis of groundbreaking pharmaceuticals aimed at combating precise maladies. Synonyms: Ethyl 4,6-O-benzylidene-b-D-thioglucopyranoside; 20701-61-5; (4aR,6S,7R,8R,8aS)-6-ethylsulfanyl-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; Ethyl 4,6-o-benzylidene-beta-D-thioglucopyranoside; SCHEMBL4171725; (4AR,6S,7R,8R,8aS)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxine-7,8-diol; 10.14272/QOMMDHDGIYADCQ-BWTKQZKTSA-N; 10.14272/QOMMDHDGIYADCQ-BWTKQZKTSA-N.1; doi:10.14272/QOMMDHDGIYADCQ-BWTKQZKTSA-N; doi:10.14272/QOMMDHDGIYADCQ-BWTKQZKTSA-N.1; Ethyl 4,6-O-benzylidene-1-thio--D-glucopyranoside; W-201808. CAS No. 20701-61-5. Molecular formula: C15H20O5S. Mole weight: 312.38. | |
| Ethyl 4,6-O-benzylidene-D-thiomannopyranoside | Ethyl 4,6-O-benzylidene-D-thiomannopyranoside is a biomedical product exhibiting its ability to inhibit specific enzymes involved in cancer growth. Additionally, this compound has shown promising results in the research of bacterial and fungal infections by disrupting their essential cellular pathways. Synonyms: Ethyl 4,6-O-[(R)-phenylmethylene]-1-thio-alpha-D-mannopyranoside; Ethyl 4,6-O-benzylidene-D-thiomannopyranoside; DTXSID701187070; (2R,4aR,6R,7S,8R,8aS)-6-ethylsulfanyl-2-phenyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxine-7,8-diol. CAS No. 142924-31-0. Molecular formula: C15H20O5S. Mole weight: 312.38. | |
| Ethyl 4-amino-b-D-glucuronide | Ethyl 4-amino-b-D-glucuronide is a notable biomedical compound serving as a precursor for the synthesis of glycosaminoglycans, critical components for ensuring optimal wellness of connective tissues. It is used for studying degenerative joint ailments, including osteoarthritand rheumatoid arthritis. Molecular formula: C8H15NO6. Mole weight: 221.21. | |
| Ethyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-thioglucopyranoside | Ethyl 4-O-acetyl-3,6-di-O-benzyl-2-deoxy-2-phthalimido-b-D-thioglucopyranoside is a complex and intriguing compound, tailored to target precise proteins or enzymes associated with inflammatory processes, oncogenesis, or infectious ailments. Synonyms: [(2R,3S,4R,5R,6S)-5-(1,3-dioxoisoindol-2-yl)-6-ethylsulfanyl-4-phenylmethoxy-2-(phenylmethoxymethyl)oxan-3-yl] acetate; (2R,3S,4R,5R,6S)-4-(Benzyloxy)-2-((benzyloxy)methyl)-5-(1,3-dioxoisoindolin-2-yl)-6-(ethylthio)tetrahydro-2H-pyran-3-yl acetate. CAS No. 138730-66-2. Molecular formula: C32H33NO7S. Mole weight: 575.7. | |
| Ethyl 4-O-allyl-3,6-di-O-benzyl-2-O-levulinoyl-b-D-thioglucopyranoside | | |
| Ethyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-a-D-thiomannopyranoside | Ethyl 6-azido-2,3,4-tri-O-benzyl-6-deoxy-a-D-thiomannopyranoside is an immensely potent compound extensively utilized for studying diverse ailments, particularly cancer, owing to its remarkable anti-neoplastic attributes. This remarkable compound operates by selectively modulating cellular pathways, curtailing neoplasm proliferation and augmenting programmed cell death or apoptosis. Molecular formula: C29H33N3O4S. Mole weight: 519.66. | |
| Ethyl 6-azido-2,4-di-O-benzoyl-3-O-benzyl-6-deoxy-a-D-thiomannopyranoside | Ethyl 6-azido-2,4-di-O-benzoyl-3-O-benzyl-6-deoxy-a-D-thiomannopyranoside is a valuable compound utilized for studying a wide range of drug-resistant infections. Molecular formula: C29H29N3O6S. Mole weight: 547.62. | |
| Ethyl 6-azido-6-deoxy-a-D-thiomannopyranoside | Ethyl 6-azido-6-deoxy-α-D-thiomannopyranoside is a pivotal compound, used in the synthesis of groundbreaking carbohydrates and glycoconjugates. It is applied in research of cancer, infectious diseases and inflammation-induced disorders. Molecular formula: C8H15N3O4S. Mole weight: 249.29. | |
| Ethyl 6-O-benzyl-2-deoxy-4-O-Fmoc-3-O-levulinoyl-2-trichloroacetamido-b-D-thioglucopyranoside | Ethyl 6-O-benzyl-2-deoxy-4-O-Fmoc-3-O-levulinoyl-2-trichloroacetamido-b-D-thioglucopyranoside is a cutting-edge biomedical product, serving as a potent inhibitor of select enzymes which makes it greatly aid in drug discovery and development. Synonyms: (2R,3S,4R,5R,6S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)oxy)-2-((benzyloxy)methyl)-6-(ethylthio)-5-(2,2,2-trichloroacetamido)tetrahydro-2H-pyran-4-yl 4-oxopentanoate; 1416144-22-3; |A-D-Glucopyranoside, ethyl 2-deoxy-6-O-(phenylmethyl)-1-thio-2-[(2,2,2-trichloroacetyl)amino]-, 4-(9H-fluoren-9-ylmethyl carbonate) 3-(4-oxopentanoate); 1416144-54-1. CAS No. 1416144-54-1. Molecular formula: C37H38Cl3NO9S. Mole weight: 779.1. | |
| Ethyl a-D-fructofuranoside | Ethyl a-D-fructofuranoside is an important ingredient used in biomedical research for studying different metabolic and genetic diseases, along with their associated complications. This compound is also widely used in the development of pharmaceutical drugs that target diabetes and other metabolic disorders. Additionally, Ethyl a-D-fructofuranoside is used in the food industry as a sweetener and flavor enhancer due to its sweet taste and low glycemic response. Synonyms: Ethyl alpha-D-fructofuranoside; Ethyl a-D-fructofuranoside; (2S,3S,4S,5R)-2-ethoxy-2,5-bis(hydroxymethyl)oxolane-3,4-diol; EA-fructofuranoside; alpha-D-Fructofuranoside, ethyl; Ethyl hex-2-ulofuranoside; SCHEMBL11153588; DTXSID101001715. CAS No. 81024-99-9. Molecular formula: C8H16O6. Mole weight: 208.21. | |
| Ethyl a-D-thiomannopyranoside | Ethyl α-D-thiomannopyranoside is an antimicrobial compound, demonstrating inhibitory efficacy, thus rendering it conducive to the formulation of studying bacterial or fungal infections. Synonyms: Ethyl a-D-thiomannopyranoside; 128946-17-8; (2R,3S,4S,5S,6R)-2-ethylsulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol; SCHEMBL2129657. CAS No. 128946-17-8. Molecular formula: C8H16O5S. Mole weight: 224.28. | |
| Ethyl a-L-thiorhamnopyranoside | | |
| Ethyl b-D-fructopyranoside | Ethyl β-D-fructopyranoside is a paramount compound assuming a crucial role in the investigation and mitigation of afflictions encompassing diabetes, cancer and metabolic disorders. CAS No. 53431-77-9. Molecular formula: C8H16O6. Mole weight: 208.21. | |
| Ethyl b-D-galactopyranoside | ETHYL β-D-GALACTOPYRANOSIDE, also called AC1NSVA, SCHEMBL2446113, is the β-D-GALACTOPYRANOSIDE type of ethyl galactoside. Studies found it is a potential inhibitor of phosphatidylinositol biosynthesis in mycobacteria. Uses: Used as an indicator ligand to determine k values for nonchromophoric carbohydrates by continuous displacement titrations, measuring either fluorescence or difference in absorption of the indicator; potential inhibitors of phosphatidylinositol biosynthesis in mycobacteria. Synonyms: Ethyl β-D-galactoside; Ethyl β-galactoside; (2R,3R,4S,5R,6R)-2-Ethoxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grades: ≥ 95%. CAS No. 18997-88-1. Molecular formula: C8H16O6. Mole weight: 208.21. | |
| Ethyl b-D-glucopyranoside | Ethyl b-D-glucopyranoside is a compound, serving as a constituent of pharmaceuticals and remedies specifically designed for studying diabetes, cardiovascular afflictions and metabolic dysfunctions. Molecular formula: C8H16O6. Mole weight: 208.21. | |
| Ethyl b-D-thiogalactopyranoside | Ethyl b-D-thiogalactopyranoside is a vital tool in biomedical research as a molecular biology reagent. It is commonly utilized to induce the expression of specific proteins in various cell systems. This compound mimics lactose and is extensively used in genetic studies to identify gene regulation patterns, protein purification assays, and as a substrate for β-galactosidase activity analysis. Synonyms: Ethyl 1-thio-D-galactopyranoside. CAS No. 56245-60-4. Molecular formula: C8H16O5S. Mole weight: 224.28. | |
| Ethyl b-D-thioxylopyranoside | Ethyl b-D-thioxylopyranoside is a pivotal constituent in the realm of biomedicine, renowned for its ubiquitous employment as a molecular probe engrossed in scrutinizing the intricate intricacies of biological mechanisms. Synonyms: Ethyl b-D-thioxylopyranoside; 2595-46-2; CHEMBL504643; SCHEMBL3441916. CAS No. 2595-46-2. Molecular formula: C7H14O4S. Mole weight: 194.25. | |
| Ethyl-b-D-triacetyl glucuronic acid methyl ester | | |
| Ethyl D-thioglucuronide | Ethyl D-thioglucuronide, an indispensable asset in the field of biomedicine, finds wide application in the investigation of pharmaceutical metabolisms as well as alcohol consumptions. This compound serves as a prime biomarker in the surveillance of ethyl alcohol ingestion and the evaluation of its impact on individuals. Synonyms: (3S,4S,5S,6S)-6-ethylsulfanyl-3,4,5-trihydroxyoxane-2-carboxylic acid;Ethyl (5xi)-1-thio-beta-D-lyxo-hexopyranosiduronic acid. CAS No. 755710-39-5. Molecular formula: C8H14O6S. Mole weight: 238.26. | |
| Ethyl (S)-3-(tert-butyldimethylsiloxy)glutarate | Ethyl (S)-3-(tert-butyldimethylsiloxy)glutarate is a remarkable biomedical compound, manifesting its efficacy in studying diverse infections and inflammatory phenomena. It is a formidable enzyme suppressor. Synonyms: Ethyl (S)-3-(tert-butyldimethylsiloxy)glutarate; 957509-27-2; (3S)-3-[tert-butyl(dimethyl)silyl]oxy-5-ethoxy-5-oxopentanoic acid; DTXSID20583683; (3S)-3-{[tert-Butyl(dimethyl)silyl]oxy}-5-ethoxy-5-oxopentanoic acid. CAS No. 957509-27-2. Molecular formula: C13H26O5Si. Mole weight: 290.43. | |
| Ethyl Tetra-O-(4-methoxybenzyl)-β-D-thiogalactopyranoside | Ethyl Tetra-O-(4-methoxybenzyl)-β-D-thiogalactopyranoside is a compound useful in organic synthesis. Synonyms: Ethyl Tetra-O-(4-methoxybenzyl)-beta-D-thiogalactopyranoside; 1434145-36-4; SCHEMBL8628196; Ethyl Tetra-O-(4-methoxybenzyl)-?-D-thiogalactopyranoside; Ethyl Tetra-O-(4-methoxybenzyl)- beta -D-thiogalactopyranoside. CAS No. 1434145-36-4. Molecular formula: C40H48O9S. Mole weight: 704.87. | |
| Ethynyl estradiol 17-acetate-3-(2,3,4-tri-O-acetyl-b-D-glucuronide) methyl ester | Ethynyl estradiol 17-acetate-3-(2,3,4-tri-O-acetyl-b-D-glucuronide) methyl ester, a prominent biomedical compound, exhibits remarkable efficacy in combatting hormone-responsive cancers. Its multifaceted mechanism inhibits tumor growth and curtails metastasis, thereby proving invaluable in the therapeutic management of breast, ovarian, and endometrial cancers. CAS No. 242130-33-2. Molecular formula: C35H42O12. Mole weight: 654.70. | |
| Ethynyl estradiol 17-b-D-glucuronide | Ethynyl estradiol 17-b-D-glucuronide, a notable pharmaceutical compound employed in the biomedical field for research objectives, holds immense relevance. It serves as a key metabolite of Ethynyl estradiol, a synthetic estrogen administered in contraceptives. By employing Ethynyl estradiol 17-b-D-glucuronide, scientists can meticulously examine the intricate processes of metabolism, distribution, and excretion of Ethynyl estradiol. This analysis fosters valuable insights, contributing to drug development endeavors and enhancing comprehension of the pharmacokinetics pertaining to estrogen-based therapies in a profound manner. Synonyms: (17a)-3-Hydroxy-19-norpregna-1,3,5(10)-trien-20-yn-17-yl b-D-glucopyranosiduronic acid. CAS No. 75803-39-3. Molecular formula: C26H32O8. Mole weight: 472.53. | |
| Etirinotecan pegol | Etirinotecan pegol, also know as pegylated irinotecan, NKTR102, is a formulation of polyethylene glycol (PEG)-encapsulated irinotecan with antineoplastic activity. The prodrug irinotecan, a semisynthetic derivative of camptothecin, is converted to the biologically active metabolite 7-ethyl-10-hydroxy-camptothecin by a carboxylesterase-converting enzyme. One thousand-fold more potent than its parent compound irinotecan, 7-ethyl-10-hydroxy-camptothecin inhibits topoisomerase I activity by stabilizing the cleavable complex of topoisomerase I and DNA, resulting in DNA breaks that inhibit DNA replication and trigger apoptosis. Pegylation provides improved drug penetration into tumors and decreases drug clearance, thereby increasing the duration of therapeutic effects while lowering the toxicity profile. Synonyms: NKTR102; NKTR 102; NKTR-102; pegylated irinotecan NKTR 102; Etirinotecan pegol. CAS No. 1193151-09-5. Molecular formula: C161H196Cl4N20O40. Mole weight: 3193.24. | |
| Etodolac Acyl Glucuronide | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-(1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetate) b-D-glucopyranuronic acid; Etodolac glucuronide. Grades: > 95%. CAS No. 79541-43-8. Molecular formula: C23H29NO9. Mole weight: 463.48. | |
| Etofibrate | Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations. Uses: Anticholesteremic agents. Synonyms: ethofibrate; Etofibrato; 3-Pyridinecarboxylic acid, 2-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl ester; Lipo-Merz; Tricerol. Grades: >98%. CAS No. 31637-97-5. Molecular formula: C18H18ClNO5. Mole weight: 363.79. | |
| Etokimab | Etokimab is a humanized monoclonal antibody against IL-33. Etokimab has been investigated for the treatment of chronic rhinosinusitis with nasal polyps. Synonyms: Antibody ANB 020. CAS No. 2022981-44-6. | |
| Etoposide Hydroxy Acid (Mixture of Diastereomers) | Etoposide hydroxy acid is a derivative of Etoposide. Etoposide is a topoisomerase I inhibitor that induces apoptosis and is used as a chemotherapeutic agent for various types of cancer, such as small-cell lung cancer. Molecular formula: C29H34O14. Mole weight: 606.57. | |
| Etoposide Impurity B | An impurity of Etoposide. Etoposide is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class. It is used in form of its salt etoposide phosphate. Synonyms: cis-Etoposide; (5R,5aS,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; [5R-[5α, 5aα, 8aα, 9β(R*)]]-9-[(4, 6-O-Ethylidene-β-D-glucopyranosyl)ox. Grades: > 95%. CAS No. 100007-56-5. Molecular formula: C29H32O13. Mole weight: 588.57. | |
| Etoposide Impurity C | An impurity of Etoposide. Etoposide is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class. It is used in form of its salt etoposide phosphate. Synonyms: α-Etoposide; (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-α-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one; Pyrano[3,2-d]-1,3-dioxin Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5. Grades: > 95%. CAS No. 100007-53-2. Molecular formula: C29H32O13. Mole weight: 588.57. | |
| Etoposide Impurity D | An impurity of Etoposide. Etoposide is a cytotoxic anticancer drug which belongs to the topoisomerase inhibitor drug class. It is used in form of its salt etoposide phosphate. Synonyms: Lignan P; (5R,5aR,8aR,9S)-9-(β-D-Glucopyranosyloxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-uro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. Grades: > 95%. CAS No. 23363-35-1. Molecular formula: C27H30O13. Mole weight: 562.53. | |
| Etoposide Phosphate | Etoposide Phosphate is a derivative of Etoposide. Etoposide is a topoisomerase II inhibitor that is widely used as an apoptosis inducer. Etoposide exhibits antineoplastic and anti-mitotic properties. It inhibits DNA synthesis and induces double-strand and single-strand DNA breaks. Synonyms: BMY-40481; Etopofos; Etoposide 4'-Phosphate. Grades: >98%. CAS No. 117091-64-2. Molecular formula: C29H33O16P. Mole weight: 668.54. | |
| Etoxybamide | Etoxybamide is used as a sedative drug candidate. Uses: Etoxybamide is used as a sedative drug candidate. Synonyms: N-(2-Hydroxyethyl)-4-hydroxybutyramide; N-(2-hydroxyethyl)-gamma-hydroxybutyramide. Grades: 98%. CAS No. 66857-17-8. Molecular formula: C6H13NO3. Mole weight: 147.17. | |
| Etrolizumab | Etrolizumab is an anti-β7 integrin monoclonal antibody. Etrolizumab has been investigated as a medication used in patients with moderately to severely active ulcerative colitis who had been previously treated with anti-tumour necrosis factor (TNF) agents. Synonyms: rhuMAb Beta7; RG7413; PRO145223. CAS No. 1044758-60-2. | |
| Evariquinone | Evariquinone is a bio-active compound isolate of sponge-derived Emericella variecolor. It showed antiproliferative activity towards KB and NCI-H460 cells at a concentration of 3.16 microg/mL. Synonyms: 9,10-Anthracenedione, 1,2,3-trihydroxy-8-methoxy-6-methyl-. Grades: 98%. CAS No. 594860-23-8. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Evinacumab | Evinacumab is a humanized anti-ANGPTL3 monoclonal antibody. Evinacumab has the potential therapeutic activity against homozygous familial hypercholesterolemia. Synonyms: Evkeeza; REGN1500. CAS No. 1446419-85-7. | |
| Evodenoson | Evodenoson is a selective A2A adenosine receptor agonist. Phase II clinical trials for the treatment of Glaucoma and Ocular hypertension were discontinued. Uses: Glaucoma;ocular hypertension. Synonyms: ATL313; ATL 313; ATL-313; DE-112; DE 112; DE112; methyl 4-[3-[6-amino-9-[(2R,3R,4S,5S)-5-(cyclopropylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]purin-2-yl]prop-2-ynyl]piperidine-1-carboxylate. Grades: 98%. CAS No. 844873-47-8. Molecular formula: C23H29N7O6. Mole weight: 499.53. | |
| Evolocumab | Evolocumab is a monoclonal antibody as well as an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9), a protein targeting LDL receptors. Inhibition of PCSK9 could prevent LDL receptors from degradation and promote the removal of LDL-C from blood circulation. Evolocumab is used for the treatment of hyperlipidemia. Uses: The treatment of hyperlipidemia. Synonyms: AMG 145; AMG-145; AMG145. CAS No. 1256937-27-5. Molecular formula: C6242H9648N1668O1996S56. Mole weight: 141800. | |
| Evomonoside | Evomonoside is a potent natural compound used for studying neurological diseases such as Alzheimer's and Parkinson's. Derived from natural sources, Evomonoside exhibits neuroprotective properties by preventing the formation of amyloid plaques in the brain. Synonyms: (3b,5b)-3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Digitoxigenin 3-rhamnoside; Digitoxigenin rhamnoside. CAS No. 508-93-0. Molecular formula: C29H44O8. Mole weight: 520.65. | |
| EVP-0015962 | EVP-0015962 is a selective Amyloid precursor protein secretase modulator under the development of FORUM Pharmaceuticals. Chronic treatment with EVP-0015962 can lower the production of Aβ42, attenuate memory deficits, and reduce Aβ plaque formation and inflammation in Tg2576 transgenic animals. EVP-0015962 shows a therapeutic alternative for disease modification in Alzheimer's disease. In Jun 2016, Phase-II for Alzheimer's disease in USA was discontinued. Uses: Alzheimer's disease. Synonyms: EVP-0015962; EVP 0015962; EVP0015962. SCHEMBL3660255; ZSERTYLZGRJLOO-UHFFFAOYSA-N; 2-(5-chloro-6-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)-3-cyclobutylpropanoic acid. Grades: 98%. CAS No. 1447811-26-8. Molecular formula: C22H19ClF6O3. Mole weight: 480.83. | |
| EX1314 | BMS-604992 is a selective and orally active growth hormone secretagogue receptor (GHSR) agonist with high-affinity binding (Ki = 2.3 nM) and strong functional activity (EC50 = 0.4 nM). It stimulates feeding in rodents. Synonyms: BMS-604992; Carbamic acid, (2-amino-2-oxoethyl)methyl-, (3-((1S)-1-((2-amino-2-methyl-1-oxopropyl)amino)-2-(phenylmethoxy)ethyl)-1,2,4-triazolo(4,3-a)pyridin-5-yl)methyl ester, monohydrochloride; (3-{(1S)-2-(Benzyloxy)-1-[(2-methylalanyl)amino]ethyl}[1, 2, 4]triazolo[4, 3-a]pyridin-5-yl)methyl (2-amino-2-oxoethyl)methylcarbamate hydrochloride (1:1). Grades: 98%. CAS No. 674343-47-6. Molecular formula: C24H32ClN7O5. Mole weight: 534.01. | |
| EX-A202 | GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection. GSK2838232 is a betulin derivative. Synonyms: GSK2838232; GSK-2838232; GSK 2838232. Grades: 98%. CAS No. 1443461-21-9. Molecular formula: C48H73ClN2O6. Mole weight: 809.57. | |
| Exeporfinium chloride | Exepor?nium is an anti-microbial that works via weakening bacteria cell walls. It can be used for the treatment for MRSA (methicillin-resistant Staphylococcus aureus) and possibly Clostridium difficile. In Apr 2016, Destiny Pharma completed a phase I/II trial in Staphylococcal infections in USA. Uses: Staphylococcal infections. Synonyms: XF73; XF 73; XF-73; 3,3'-((porphyrin-5,15-diylbis(4,1-phenylene))bis(oxy))bis(N,N,N-trimethylpropan-1-aminium) chloride;756818-36-7 (XF-73 Free). Grades: 98%. CAS No. 718638-68-7. Molecular formula: C44H50Cl2N6O2. Mole weight: 765.82. | |
| Ezetimibe-D-glucuronide D4 | Ezetimibe-D-glucuronide D4 is an esteemed compound in the biomedical field, aiding in the research of hypercholesterolemia and familial hypercholesterolemia. Manifesting as a remarkable cholesterol absorption inhibitor, it deftly curtails cholesterol levels through the hindrance of intestinal cholesterol assimilation and associated phytosterol uptake. Synonyms: Ezetimibe-d4 β-D-Glucuronide. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe hydroxy-D-glucuronide D4 | Ezetimibe hydroxy-D-glucuronide D4 is a metabolite of stable isotope-labeled Ezetimibe, playing a profound role in illuminating the intricate mechanisms of Ezetimibe metabolism, pharmacokinetics and elimination pathways. Molecular formula: C30H25D4F2NO9. Mole weight: 589.57. | |
| Ezetimibe Hydroxy Glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe Hydroxy β-D-Glucuronide; (1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl β-D-Glucopyranosiduronic Acid. Grades: > 95%. CAS No. 536709-33-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezetimibe Phenexy Glucuronide | A metabolite of Ezetimibe. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Synonyms: Ezetimibe phenoxy Glucuronide. Grades: > 95%. CAS No. 190448-57-8. Molecular formula: C30H29F2NO9. Mole weight: 585.55. | |
| Ezlopitant | Ezlopitant, also known as CJ-11,974, is a NK1 receptor antagonist. It has antiemetic and antinociceptive effects. Synonyms: CJ 11,974; CJ-11974; CJ11974; (7S,8S)-7-[di(phenyl)methyl]-N-[(2-methoxy-5-propan-2-ylphenyl)methyl]-1-azabicyclo[2.2.2]octan-8-amine. CAS No. 147116-64-1. Molecular formula: C31H38N2O. Mole weight: 454.66. | |
| Fadolmidine HCl | Fadolmidine Hydrochloride, is a novel α2-adrenoceptor (α2-AR) agonist, having antinociception properties. It can be used for the control of inflammatory, postoperative and neuropathic pain. Synonyms: Fadolmidine HCl; MPV-2426; MPV 2426; MPV2426; 3-((1H-imidazol-4-yl)methyl)-2,3-dihydro-1H-inden-5-ol hydrochloride. Grades: 97%. CAS No. 189353-32-0. Molecular formula: C13H15ClN2O. Mole weight: 250.72. | |
| Fadrozole | Fadrozole is a potent and selective inhibitor of aromatase with IC50 of 4.5 nM. Uses: Antineoplastic agents, hormonal. Synonyms: Benzonitrile, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-; CGS 16949A (free base); 5-p-cyanophenyl-5,6,7,8-tetrahydroimidazo[1,5-a]pyridine; 4-{5H,6H,7H,8H-imidazo[1,5-a]pyridin-5-yl}benzonitrile. Grades: 95%. CAS No. 102676-47-1. Molecular formula: C14H13N3. Mole weight: 223.27. | |
| Fagomine | Fagomine is a captivating natural alkaloid compound showcasing its exceptional attributes in studying diabetes and viral infections. Synonyms: D-Fagomine; (2S,3R,4S)-2-(Hydroxymethyl)-3,4-piperidinediol. CAS No. 53185-12-9. Molecular formula: C6H13NO3. Mole weight: 147.17. | |
| Farletuzumab | Farletuzumab is a humanized monoclonal antibody that binds to GP-3 antigen and triggers a host immune response against GP-3 expressing cells. Farletuzumab has been investigated for the treatment of ovarian cancer. Synonyms: MORAb-003. CAS No. 896723-44-7. | |
| Farudodstat | Farudodstat is an orally active and potent inhibitor of DHODH (human dihydroorotate dehydrogenase). It inhibits the proliferation of MOLM-14 and KG-1 acute myeloid leukemia (AML) cells (IC50s = 0.582 and 0.382 μM, respectively), as well as induces apoptosis in the same cells when used at concentrations of 0.5 and 1 μM. Synonyms: 2-[(3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino]pyridine-3-carboxylic acid; ASLAN003; 2-[(3,5-Difluoro-3'-methoxy-4-biphenylyl)amino]nicotinic Acid; 3-Pyridinecarboxylic acid, 2-[(3,5-difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino]-; 2-((3,5-Difluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)amino)nicotinic acid; 2-[(3,5-difluoro-3'-methoxy[1,1'-biphenyl]-4-yl)amino]-3-pyridinecarboxylic acid. Grades: ≥98%. CAS No. 1035688-66-4. Molecular formula: C19H14F2N2O3. Mole weight: 356.32. | |
| Fasinumab | Fasinumab is a human monoclonal antibody to nerve growth factor (NGF). Fasinumab has been undergoing clinical trials for the treatment of osteoarthritis (OA) hip and/or knee pain. Synonyms: REGN475. CAS No. 1190239-42-9. | |
| Fazarabine | Fazarabine, also known as Kymarabine, is an orally-active pyrimidine analogue of an aza-substituted cytidine in which the ribose moiety is replaced by an arabinose sugar. Similar in action to cytarabine, fazarabine is phosphorylated by deoxycytidine kinase to a triphosphate form which competes with thymidine for incorporation into DNA; its incorporation into DNA inhibits DNA synthesis, resulting in tumor cell death and tumor necrosis. The presence of deoxycytidine kinase in a tumor is a determinant of tumor sensitivity to this drug. Synonyms: CCRIS 93; CCRIS-93; CCRIS93; NSC 281272; NSC-281272; NSC281272; Ara-AC; 5-Azacytosine arabinoside; 1-beta-D-Arabinofuranosyl-5-azacytosine. CAS No. 65886-71-7. Molecular formula: C8H12N4O5. Mole weight: 244.20. | |
| Febuxostat Acyl Glucuronide | An impurity of Febuxostat. Febuxostat is an antihyperuricemic nonpurine inhibitor of both the oxidized and reduced forms of xanthine oxidase. Synonyms: Febuxostat Acyl-β-D-glucuronide. Grades: > 95%. CAS No. 1351692-92-6. Molecular formula: C22H24N2O9S. Mole weight: 492.50. | |
| Fenimide | Fenimide is a bio-active chemical compound. It is used as an antipsychotic drug. Uses: Fenimide is used as an antipsychotic drug. Synonyms: CI-419; CI 419; PM 1807; 3-Ethyl-2-methyl-2-phenylsuccinimide; 2,5-Pyrrolidinedione, 4-ethyl-3-methyl-3-phenyl-. Grades: 98%. CAS No. 60-45-7. Molecular formula: C13H15NO2. Mole weight: 217.26. | |
| Fenofibric Acyl Glucuronide | A derivative of Fenofibrate. Fenofibrate is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. Synonyms: Fenofibric acid acyl glucuronide. Grades: > 95%. CAS No. 60318-63-0. Molecular formula: C23H23ClO10. Mole weight: 494.88. | |
| Fezakinumab | Fezakinumab is a human monoclonal antibody that targets interleukin-22. Fezakinumab has been developed for the treatment of psoriasis and rheumatoid arthritis. Synonyms: ILV 094; ILV-094; ILV094. CAS No. 1007106-86-6. | |
| FH535 | FH535 is a Wnt/β-catenin signaling inhibitor. It was shown to inhibit proliferation and motility of various cancer stem cells including liver cancer stem cells and colon cancer cells. Synonyms: 2,5-dichloro-N-(2-methyl-4-nitrophenyl)benzenesulfonamide. Grades: >98%. CAS No. 108409-83-2. Molecular formula: C13H10Cl2N2O4S. Mole weight: 361.20. | |
| FI-700 | FI-700 is a novel and potent FLT3 inhibitor with promising antileukemia activity. FI-700 showed a potent IC(50) value against FLT3 kinase at 20 nmol/L in an in vitro kinase assay. FI-700 showed selective growth inhibition against mutant FLT3-expressing leukemia cell lines and primary acute myeloid leukemia cells, whereas it did not affect the FLT3 ligand (FL)-driven growth of Wt-FLT3-expressing cells. Oral administration of FI-700 induced the regression of tumors in a s.c. tumor xenograft model and increased the survival of mice in an i.v. transplanted model. Furthermore, FI-700 treatment eradicated FLT3/ITD-expressing leukemia cells, both in the peripheral blood and in the bone marrow. Synonyms: FI700; FI 700. CAS No. 866883-79-6. Molecular formula: C21H29N9O. Mole weight: 423.53. | |
| Ficlatuzumab | Ficlatuzumab is a humanized monoclonal antibody that binds to hepatocyte growth factor (HGF), resulting in inhibtion of c-Met signaling pathway. Ficlatuzumab has been approved for the treatment of head and neck cancer. CAS No. 1174900-84-5. | |
| Fidarestat | Fidarestat is a aldose reductase inhibitor originated by Sanwa Kagaku Kenkyusho. It was very effective in significantly alleviating some symptoms of diabetic polyneuropathy. Long-term treatment with SNK-860 has a beneficial preventive effect on the development of experimental diabetic neuropathy. In addition, Fidarestat is also a promising drug targeting autophagy in Colorectal Carcinoma. Uses: Diabetic neuropathies. Synonyms: SNK860; SNK-860; SNK 860; SK860; SK-860; SK 860; Fidarestat; Aldos. (2S,4S)-6-fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide; Aldos;SNK 860. Grades: 98%. CAS No. 136087-85-9. Molecular formula: C12H10FN3O4. Mole weight: 279.23. | |
| Figitumumab | Figitumumab is a monoclonal antibody that targets the insulin-like growth factor type I receptor (IGF1R). Figitumumab binds to IGF1R, resulting in a reduction in receptor expression on tumor cells that express IGF1R and inhibition of tumor growth. Synonyms: CP-751871. CAS No. 943453-46-1. | |
| FIIN-1 | FIIN-1 is a potent, irreversible and selective FGFR inhibitor with IC50s of 9.2, 6.2, 11.9 and 189 nM against FGFR1/2/3/4, respectively. FIIN-1 binds to FGFR1/2/3/4 and Flt1/4 with Kds of 2.8, 6.9, 5.4, 120 nM and 32, 120 nM, respectively. Synonyms: FGFR irreversible inhibitor-1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide; Fibroblast Growth Factor Receptor Irreversible Inhibitor 1; N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]acrylamide. Grades: ≥95%. CAS No. 1256152-35-8. Molecular formula: C32H39Cl2N7O4. Mole weight: 656.60. | |
| Filgotinib | Filgotinib is a potent and selective JAK1 inhibitor exhibiting 30-fold selectivity over JAK2. It was shown to inhibit Th1 and Th2 differentiation and to a lesser extent the differentiation of Th17 cells in vitro. Filgotinib has the potential for the treatment of rheumatoid arthritis and possibly other immune-inflammatory diseases. Synonyms: GLPG0634; GLPG-0634; N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide. Grades: >98%. CAS No. 1206161-97-8. Molecular formula: C21H23N5O3S. Mole weight: 425.507. | |
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