BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Reagent for the guanylation of amines. Synonyms: 1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea; 1,3-di-Boc-2-methylisothiourea. Grade: ≥ 98 % (TLC). CAS No. 107819-90-9. Molecular formula: C12H22N2O4S. Mole weight: 290.38.
N,N-Carbonyldiimidazole
CDI is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates. Synonyms: CDI; 1,1'-Carbonyldiimidazole; Di-1H-imidazol-1-yl-methanone; Bis(imidazol-1-yl) Ketone; Bis(imidazol-1-yl)methanone; Diimidazol-1-yl Ketone; N,N'-Carbonylbis(imidazole); N,N'-Carbonyldiimidazole; NSC 67203. Grade: 98%. CAS No. 530-62-1. Molecular formula: C7H6N4O. Mole weight: 162.15.
N,N-Diacetyl-Lys-D-Ala-D-Ala
N,N-Diacetyl-Lys-D-Ala-D-Ala is a substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases). Synonyms: Diacetyl-Lys-D-Ala-D-Ala-OH; (Ac)2-L-Lys-D-Ala-D-Ala; N-acetyl-N6-acetyl-L-lysyl-D-alanyl-D-alanine; N2,N6-Diacetyl-L-lysyl-D-alanyl-D-alanine; Nα,Nepsilon-Diacetyl-Lys-D-Ala-D-Ala; D-Alanine, N-(N-(N2,N6-diacetyl-L-lysyl)-D-alanyl)-; (R)-2-((R)-2-((S)-2,6-Diacetamidohexanamido)propanamido)propanoic acid. Grade: 95%. CAS No. 24570-39-6. Molecular formula: C16H28N4O6. Mole weight: 372.42.
N,N'-Diacetyl-lysinyl-D-alanyl-D-lactic acid
A depsipeptide substrate for penicillin-sensitive D-alanine carboxypeptidases (DD-carboxypeptidases). Synonyms: Nalpha,Nepsilon-Diacetyl-Lys-D-Ala-D-lactic acid. Grade: >99%. CAS No. 65882-12-4. Molecular formula: C16H27N3O7. Mole weight: 373.40.
4-Hydroxystachydrine belongs to the class of organic compounds known as proline and derivatives. Synonyms: 4-Hydroxystachydrine. Molecular formula: C7H13NO3. Mole weight: 159.18.
N,N'-Disuccinimidyl carbonate
N,N'-Disuccinimidyl Carbonate is a commonly used reagent for the preparation of N-succinimidyl esters of N-protected amino acids, activated carbonate, synthesis of urea, carbamates and coupling of ligands to proteins. The coupling reagent property of N,N'-Disuucinimidyl Carbonate speeds up coupling process, while reduces the loss of chiral integrity. Synonyms: 1,1'-[Carbonylbis(oxy)]bis-2,5-pyrrolidinedione; 1-[[[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl]oxy]-2,5-pyrrolidinedione; Bis(2,5-dioxopyrrolidin-1-yl) Carbonate; Bis(N-succinimidyl) Carbonate; Bis(succinimidyl) Carbonate; Carbonic Acid bis(2,5-dioxopyrrolidin-1-yl) Ester; Di(2,5-dioxopyrrolidin-1-yl) Carbonate; Disuccimidyl carbonate; Disuccinimidyl Carbonate; N,N-Disuccinimidyl Carbonate; N,N'-Disuccinimido Carbonate; DSC; N-Succinimidyl carbonate; EINECS 277-730-3. Grade: 98%. CAS No. 74124-79-1. Molecular formula: C9H8N2O7. Mole weight: 256.17.
N,N'-Di(t-butoxycarbonyl)cystamine
A building block for the synthesis of thioethyl-modified peptides. Synonyms: Di-Boc-Cystamine; (Boc-NH-EtS)2; Bis-Boc-cystamine; N,N'-Bis-tert-butoxycarbonyl-cystamine; tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyldisulfanyl]ethyl]carbamate; [2-(2-tert-butoxycarbonylamino-ethylsulfanyl)-thioethyl]carbamic acid tert-butyl ester; di-tert-Butyl(disulfanediylbis(ethane-2,1-diyl))dicarbamate; tert-butyl 2,2'-disulfanediylbis(ethane-2,1-diyl)dicarbamate; N,N-di-(tert-butyloxycarbonyl)-cystamine. Grade: ≥ 98% (TLC). CAS No. 67385-10-8. Molecular formula: C14H28N2O4S2. Mole weight: 352.51.
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride, often abbreviated as TMPD or TMPD dihydrochloride, is a chemical compound used as a redox indicator. It is commonly used in biochemical assays and tests, such as the oxidase test, to detect the presence of certain oxidase enzymes. In the presence of these enzymes, TMPD changes color, indicating a positive result. Uses: Indicators and reagents. Synonyms: TMPD; 1,4-Benzenediamine, N,N,N',N'-tetramethyl-, dihydrochloride; 1,4-Benzenediamine, N1,N1,N4,N4-tetramethyl-, hydrochloride (1:2); Wurster's reagent dihydrochloride; p-Phenylenediamine, N,N,N',N'-tetramethyl-, dihydrochloride; 1,4-Bis(dimethylamino)benzene dihydrochloride; N,N,N',N'-Tetramethyl-1,4-benzenediamine dihydrochloride; N,N,N',N'-Tetramethyl-1,4-phenylenediamine dihydrochloride; Tetramethyl-p-phenylenediamine dihydrochloride. Grade: 98% by HPLC. CAS No. 637-01-4. Molecular formula: C10H18Cl2N2. Mole weight: 237.17.
N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate is a reagent used in the preparation of hindered Barton esters from hindered carboxylic acid precursors. N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is also used as a coupling reagents for peptide bond formations and amidation reactions. Synonyms: S-(1-OXIDO-2-PYRIDYL)-N,N,N',N'-TETRAMETHYLTHIURONIUM-PF6; N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuron; S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuron; HOTT N,N,N'',N''-TETRAMETHYL-S-(1-OXIDO-2-PYRIDYL)THIURONIUM HEXAFLUOROPHOSPHATE; HOTT; S-(2-Pyridyl)-N,N,N',N'-tetramethylthiuronium N-oxide hexafluorophosphate; hott; AmbotzRL-1156; S-(1-Oxido-2-pyridinyl) 1,1,3,3-tetramethylthiouronium Hexafluorophosphate. Grade: 98%. CAS No. 212333-72-7. Molecular formula: C10H16F6N3OPS. Mole weight: 371.28.
Used for preparation of an inhibitor of the NLS-derived BC peptides. Synonyms: N-Methoxymethylamine hydrochloride. Grade: ≥ 99 % (GC). CAS No. 6638-79-5. Molecular formula: C2H7NO·HCl. Mole weight: 97.55.
It is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist. It is used as an additive in whitening or spot corrective products. Synonyms: Melanostatine-5 acetate salt; H-Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2.CH3CO2H; L-methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide acetic acid. Grade: ≥98%. Molecular formula: C61H87N15O9S.C2H4O2. Mole weight: 1266.56.
Non-β-Amyloid component of Alzheimer's Disease (NAC) (8-18)
Non-β-Amyloid component of Alzheimer's Disease (NAC) (8-18) is the 8-18 amino acid residue of Non-β-Amyloid component of Alzheimer's Disease (NAC). NAC is the second component in the amyloid from brain tissue of patients affected with Alzheimer's disease. Synonyms: Gly-Ala-Val-Val-Thr-Gly-Val-Thr-Ala-Val-Ala; Non-Aβ component of Alzheimer's Disease (NAC) (8-18); Non-Abeta component of Alzheimer's Disease (NAC) (8-18). Molecular formula: C41H73N11O14. Mole weight: 944.15.
Non-disulfide-bridged peptide 43
Non-disulfide-bridged peptide 43 is an antimicrobial peptide found in Opisthacanthus cayaporum (South American scorpion), and has antibacterial activity. Synonyms: Trp-Ala-Thr-Leu-Ala-Lys-Gly-Ala-Leu-Lys-Leu-Ile-Pro-Thr-Ile-Ala-Asn-Ala-Phe-Ser-Ser-Lys-Ser; NDBP-43. Grade: ≥95%. Molecular formula: C111H182N28O30. Mole weight: 2388.84.
Non-disulfide-bridged peptide 5.5
Non-disulfide-bridged peptide 5.5 is an antimicrobial peptide found in Hadrurus gertschi (Scorpion, Hadrurus gertschi), and has antibacterial activity. Synonyms: Ile-Phe-Ser-Ala-Ile-Ala-Gly-Leu-Leu-Ser-Asn-Leu-Leu; NDBP-5.5. Grade: ≥97%. Molecular formula: C63H106N14O17. Mole weight: 1331.62.
Non-disulfide-bridged peptide 5.6
Non-disulfide-bridged peptide 5.6 is an antimicrobial peptide found in Hadrurus gertschi (Scorpion, Hadrurus gertschi), and has antibacterial activity. Synonyms: Phe-Ile-Phe-Asp-Leu-Leu-Lys-Lys-Leu-Val; NDBP-5.6. Grade: ≥97%. Molecular formula: C63H102N12O13. Mole weight: 1235.58.
Non-disulfide-bridged peptide 57
Non-disulfide-bridged peptide 57 is an antimicrobial peptide found in Opisthacanthus cayaporum (South American scorpion), and has antibacterial activity. Synonyms: Leu-Ser-Ala-Ile-Trp-Ser-Gly-Ile-Lys-Ser; NDBP-57. Grade: ≥96%. Molecular formula: C49H80N12O14. Mole weight: 1061.25.
Non-disulfide-bridged peptide 58
Non-disulfide-bridged peptide 58 is an antimicrobial peptide found in Opisthacanthus cayaporum (South American scorpion), and has antibacterial activity. Synonyms: Ile-Leu-Gly-Lys-Ile-Trp-Glu-Gly-Val-Lys-Ser; NDBP-58. Grade: ≥97%. Molecular formula: C58H96N14O15. Mole weight: 1229.49.
Non-specific lipid-transfer protein 1
Non-specific lipid-transfer protein 1 is an antimicrobial peptide found in Nigella sativa (Black cumin), and has antifungal activity. Synonyms: LTP 1; Ile-Ser-Cys-Gln-Asp-Val-Lys-Gln-Ser-Leu-Ala-Pro-Cys-Leu-Pro-Tyr-Val-Thr-Gly-Arg-Ala-Pro-Lys-Pro-Ala; StnsLTP1. Grade: ≥96%.
Nonspecific lipid-transfer protein 1
Nonspecific lipid-transfer protein 1 is an antimicrobial peptide found in Vigna radiata var. radiata (mung bean), and has antibacterial and antifungal activity. Synonyms: Met-Thr-Cys-Gly-Gln-Val-Gln-Gly-Asn-Leu-Ala-Gln-Cys-Ile-Gly-Phe-Leu-Gln-Lys-Gly-Gly. Grade: ≥98%.
Nosiheptide precursor
Nosiheptide precursor is an antimicrobial peptide found in Streptomyces actuosus, and has antibacterial activity. Synonyms: Cys-Thr-Thr-Cys-Glu-Cys-Cys-Cys-Ser-Cys-Ser. Grade: ≥90%.
NOTA-3PRGD2
NOTA-3PRGD2. Mole weight: 2500.84.
NOTA-Bis(t-butyl ester)
It is the PDC linker targeting moietie of peptide drug conjugates (PDCs). Synonyms: 1,4-Bis(1,1-dimethylethyl)hexahydro-1H-1,4,7-triazonine-1,4,7-triacetate; NOTA-bis(tBu)ester; NOTA-bis(t-Bu ester); 1H-1,4,7-Triazonine-1,4,7-triacetic acid, hexahydro-, 1,4-bis(1,1-dimethylethyl) ester; 1,4-Bis(1,1-dimethylethyl) hexahydro-1H-1,4,7-triazonine-1,4,7-triacetate; 2-(4,7-Bis(2-(tert-butoxy)-2-oxoethyl)-1,4,7-triazonan-1-yl)acetic acid. Grade: ≥95%. CAS No. 1161415-28-6. Molecular formula: C20H37N3O6. Mole weight: 415.52.
NOTA-Ser-Asn-Asp-Arg-Pro-Pro-Asn-Ile-Leu-Gln-Gln-Arg is a peptide that was used in a study to image tumors. The peptide was used in a study of two HCC subcutaneous tumor models, HepG2 and SMMC-7721.
NOTA-TATE
NOTA-TATE is a peptide conjugated with covalently bonded DOTA bifunctional chelator. NOTA-TATE can be used in PET scan for tumor imaging. Synonyms: NOTA-(D-Phe)-Cys-Tyr-(D-Trp)-Lys-Thr-Cys-Thr (Disulfide bond Cys2/Cys7); NOTA-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr (Disulfide bond Cys2/Cys7). Molecular formula: C62H84N12O17S2. Mole weight: 1333.54.
Novexatin
Novexatin is a novel antifungal peptide specifically designed for the topical treatment of onychomycosis. Synonyms: NP-213; NP213; NP 213. Grade: >98%. CAS No. 942577-31-3. Molecular formula: C42H84N28O7. Mole weight: 1093.32.
NP-12
NP-12 is a peptide antagonist of the PD-1 signaling pathway and can be used as an immunomodulator for cancer therapy. Synonyms: NP 12; NP12; L-Glutamic acid, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-; Ser-Asn-Thr-Ser-Glu-Ser-Phe-Lys(Ser-Asn-Thr-Ser-Glu-Ser-Phe)-Phe-Arg-Val-Thr-Gln-Leu-Ala-Pro-Lys-Ala-Gln-Ile-Lys-Glu-NH2. Grade: ≥98%. CAS No. 1353564-66-5. Molecular formula: C142H225N39O49. Mole weight: 3262.53.
N-palmitoylglycine
N-palmitoylglycine contains a 16-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. It inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Synonyms: palmitoyl glycine; PalGly; N-(1-Oxohexadecyl)Glycine; N-Ethanoyl-Hexadecanamide. Grade: ≥ 98% (HPLC). CAS No. 2441-41-0. Molecular formula: C18H35NO3. Mole weight: 313.50.
N-Phenylglycine is a derivative of Glycine. N-Phenylglycine is also sometimes coupled with Glycidyl methacrylate to create a surface active comonomer that promotes adhesive bonding of materials to hard tooth tissues. Synonyms: Anilinoacetic acid; 2-(phenylamino)acetic acid; Glycine, phenyl-; N-Ph-Gly-OH; Nα-Aminophenylacetic acid; (Phenylamino)acetic acid; N-Phenylaminoacetic acid; NPG; NSC 83567. Grade: > 97 %. CAS No. 103-01-5. Molecular formula: C8H9NO2. Mole weight: 151.16.
N-[(Phenylmethoxy)carbonyl]-L-phenylalanyl-L-tyrosyl-L-leucine is a synthetic peptide substrate for the protease carboxypeptidase and can be cleaved by trypsin to Z-Phe-Tyr and Leu. Synonyms: N-[(Benzyloxy)carbonyl]-L-phenylalanyl-L-tyrosyl-L-leucine; Z-Phe-Tyr-Leu; Cbz-Phe-Tyr-Leu; Cbz-Phe-Tyr-Leu-OH. CAS No. 35971-71-2. Molecular formula: C32H37N3O7. Mole weight: 575.65.