BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| L-Rhamnose bis(ethylsulfone) | L-Rhamnose bis(ethylsulfone) is a compound commonly used as an essential intermediate for the synthesis of drugs used to study various diseases such as diabetes, cancer and inflammation. Synonyms: 1,1-Diethylsulfonyl-L-rhamnose. CAS No. 54253-49-5. Molecular formula: C10H22O8S2. Mole weight: 334.41. |  |
| L-Rhamnose diethyl mercaptal | L-Rhamnose diethyl mercaptal, an indispensable component extensively employed in the biomedical sector, assumes a pivotal function in the advancement of therapeutics intended to address an array of maladies. CAS No. 6748-70-5. Molecular formula: C10H22O4S2. Mole weight: 270.41. | |
| L-Rhamnose monohydrate - USP | L-Rhamnose monohydrate - USP is an exemplary pharmaceutical-grade biomedical product aiding in studying diverse bacterial and viral infections. Prominently utilized in the formulation of groundbreaking antimicrobial compounds and advanced vaccines, this unadulterated and USP-compliant natural sugar epitomizes exceptional reliability and efficacy in confronting formidable infectious pathogens. Synonyms: 6-Deoxy-L-mannose; a-L-Rhamnose monohydrate. Molecular formula: C6H12O5 H2O. Mole weight: 182.17. | |
| L-Rhodinose | L-Rhodinose is an innate sugar alcohol emanating enticing prospects for studying metabolic ailments and diabetes. Synonyms: 2,3,6-Trideoxy-L-threo-hexose. Molecular formula: C6H12O3. Mole weight: 132.16. | |
| L-Ribonic acid-1,4-lactone | L-Ribonic acid-1,4-lactone is a prominent constituent assuming a paramount position acknowledged for its antiviral attributes. It assumes a pivotal function in the synthesis of medicaments targeting viral ailments and susceptibilities. This compound manifests extraordinary potency in the research of a diverse array of viral maladies, such as influenza and herpes. Synonyms: L-Ribono-1,4-lactone; L-Ribonic acid gamma-lactone; (3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)dihydrofuran-2(3H)-one; 3beta,4beta-Dihydroxy-5alpha-(hydroxymethyl)-4,5-dihydrofuran-2(3H)-one; L-Ribonic acid, γ-lactone. Grades: ≥97%. CAS No. 133908-85-7. Molecular formula: C5H8O5. Mole weight: 148.12. | |
| L-Ribopyranosyl thiosemicarbazide | L-Ribopyranosyl thiosemicarbazide is a compound used in the biomedical industry for its potential in developing novel drugs to study parasitic diseases such as Chagas disease. This compound has shown promising antiparasitic activity by inhibiting specific enzymes essential for the survival and proliferation of the parasite. Molecular formula: C6H13N3O4S. Mole weight: 223.25. | |
| L-Ribose | L-Ribose is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. Synonyms: L-(+)-Ribose; aldehydo-L-ribose; aldehydo-L-ribo-pentose; L-Ribofuranose. Grades: ≥98% by HPLC. CAS No. 24259-59-4. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| L-Ribose-5-phosphate disodium salt hydrate | L-Ribose-5-phosphate disodium salt hydrate is an indispensable compound sector, exhibiting an immense significance in a multitude of intricate biochemical pathways by facilitating the amalgamation of nucleotides, DNA and RNA. Its extensive employment encompasses the realm of drug compound for studying afflictions such as cancer, viral infections and metabolic anomalies. Molecular formula: C5H9Na2O8P. Mole weight: 274.07. | |
| L-Ribulose | L-Ribulose is a pivotal carbohydrate extensively employed, assuming a fundamental role in the metabolic mechanisms prevailing within organisms, more specifically, in the illustrious Calvin cycle of photosynthesis. Synonyms: L-erythro-Pentulose; L-Adonose. CAS No. 2042-27-5. Molecular formula: C5H10O5. Mole weight: 150.13. | |
| L-Sorbose | L-Sorbose is an intriguing monosaccharide, having garnered particular interest in studying diseases such as diabetes and cancer. Its distinctive antioxidant attributes have rendered it a subject of extensive scrutiny in reducing blood glucose and impeding tumor proliferation. Synonyms: (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one. CAS No. 87-79-6. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| L-Sorbose-1-phosphate | L-Sorbose-1-phosphate is a pivotal compound operating indispensably as a vital intermediary within the metabolic cascade, aiding in studying the intricate affliction known as hereditary fructose intolerance, an exceedingly rare metabolic anomaly. Synonyms: L-Sorbose-1-phosphate; 1-o-phosphonohex-2-ulose; D-Fructose 1-phosphate; 15978-08-2; 49594-02-7; SCHEMBL19512307; DTXSID70864651; 91746477-33C4-4DC4-A606-4E772E044460. CAS No. 49594-02-7. Molecular formula: C6H13O9P. Mole weight: 260.14. | |
| L-Sorbose-1-phosphate potassium salt | L-Sorbose-1-phosphate potassium salt is a multifaceted compound assuming a pivotal role in the progressive field, steering the development of groundbreaking pharmaceuticals. Its unparalleled attributes are harnessed aptly to pinpoint and modulate intricate metabolic pathways, intricately associated with targeted disorders. Molecular formula: C6H12KO9P. Mole weight: 298.23. | |
| L-Tagatose | L-Tagatose, derived from d-tagatose, is a low-calorie natural sweetener used in studying diseases related to high blood sugar levels, such as diabetes. Synonyms: L-Tagatose; 17598-82-2; L-LYXO-2-hexulose; Tagatose, L-; (3R,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one; L-Tagatose [MI]; keto-L-tagatose; 41IX5VHE3I; 551-68-8; 41847-60-3; UNII-41IX5VHE3I; L - tagatose; D-Psicose, >=95%; SCHEMBL9710274; BJHIKXHVCXFQLS-LFRDXLMFSA-N; CHEBI:134275; DTXSID901318451; MFCD00083478; HY-W145570; CS-0214560; T2535; C21523; D92607; Q27258441. CAS No. 17598-82-2. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| L-Talitol | L-Talitol is a biomedical compound used in the treatment of diabetes-related nerve damage and fibromyalgia symptoms. As a polyol, it acts as a sugar substitute and exhibits antioxidant properties. L-Talitol aids in inhibiting advanced glycation end products (AGEs) formation and reducing oxidative stress, thus preserving nerve function and alleviating pain associated with these conditions. Synonyms: (2S,3R,4S,5S)-Hexane-1,2,3,4,5,6-hexaol; (2S,3S,4R,5S)-hexane-1,2,3,4,5,6-hexol; Altritol, L-; (2S,3R,4S,5S)-HEXANE-1,2,3,4,5,6-HEXOL. CAS No. 60660-58-4. Molecular formula: C6H14O6. Mole weight: 182.17. | |
| L-Talose | L-Talose is an extraordinary biomedical product, aiding in studying intricate metabolic disorders. Notably, the prodigious implications of L-Talose burgeon in the realm of studying diabetes and diverse metabolic predicaments, courtesy of its active engagement in the multifaceted labyrinth of carbohydrate metabolism pathways. Synonyms: L-Talose; 23567-25-1; L-(-)-TALOSE; (2R,3R,4R,5S)-2,3,4,5,6-pentahydroxyhexanal; aldehydo-L-talose; EINECS 245-744-9; L(-)-Talose; SCHEMBL16164349; CHEBI:86058; DTXSID701319160; GEO-04669; MFCD00135850; AKOS027320154; HY-W145580; AS-56035; CS-0214572; FT-0624556; T1767; D92524; A878210; W-201988; Q27158868. CAS No. 23567-25-1. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| L-TBOA ammonia salt | L-TBOA is a potent and competitive blocker of human excitatory amino acid transporters (EAAT1-3; IC50 values 23 μM, 3.8 μM, 7.0 μM for EAAT1, EAAT2, and EAAT3, respectively). L-TBOA is the most active isomer of DL-TBOA, and exhibits high selectivity for EAATs over ionotropic and metabotropic glutamate receptors. Synonyms: (2S,3S)-2-amino-3-phenylmethoxybutanedioic acid ammonia salt. Grades: 99%. Molecular formula: C11H13NO5.NH3. Mole weight: 256.26. | |
| L-Threitol | L-Threitol is a useful synthetic intermediate. It was used to synthesize novel aza-sugar-based metalloproteinase MMP/ADAM inhibitors. It is also a diastereomer of Erythritol which is a food additive. Synonyms: 1,3,5-orthoformate-myo-inositol; meso-D-myo-inositol-1,3,5-O-orthoformate; L-1,2,3,4-Butanetetrol; myo-inositol 1,3,5-monoorthoformate; (2s,3s)-butane-1,2,3,4-tetraol. Grades: ≥ 95%. CAS No. 2319-57-5. Molecular formula: C4H10O4. Mole weight: 122.12. | |
| L-threo-PPMP hydrochloride | L-threo-PPMP is an inhibitor of glucosylceramide synthetase. Synonyms: L-threo-PPMP HCl; L-threo-1-phenyl-2-Palmitoylamino-3-morpholino-1-propanol hydrochloride; N-[(1R,2R)-1-hydroxy-3-morpholin-4-yl-1-phenylpropan-2-yl]hexadecanamide hydrochloride. Grades: ≥98%. CAS No. 207278-87-3. Molecular formula: C29H50N2O3·HCl. Mole weight: 511.18. | |
| L-Threose | L-Threose is an intricately structured carbohydrate compound assuming an indispensable function in the amalgamation of a myriad of pharmaceutical compounds vital for studying bacterial and viral assailants. Its pivotal involvement extends to the research of remedies targeting a spectrum of afflictions, encompassing cancer and diabetes. CAS No. 95-44-3. Molecular formula: C4H8O4. Mole weight: 120.1. | |
| L-Turicine | L-Turicine is a biomedically inclined natural compound, extensively investigated for its neurological safeguarding attributes. L-Turicine exhibits considerable potential in studying neurodegenerative ailments like Alzheimer's and Parkinson's disease. Synonyms: N,N-Dimethyl cis-4-hydroxy-L-proline; cis-Betonicine; (-)-Turicine; Allohydroxy-L-proline betaine; Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, inner salt, (2S,4S)-; Pyrrolidinium, 2-carboxy-4-hydroxy-1,1-dimethyl-, inner salt, (2S-cis)-. CAS No. 174851-67-3. Molecular formula: C7H13NO3. Mole weight: 159.18. | |
| LTURM34 | LTURM34, with antiproliferative activity of a wide range of tumor cell lines in vitro, is a potent and selective DNA-PK inhibitor (IC50 = 0.034 μM) with excellent selectivity over the Class I PI3K isoforms. Synonyms: LTURM34; LTURM 34; LTURM-34; 8-dibenzothiophen-4-yl-2-morpholin-4-yl-1,3-benzoxazin-4-one; CHEMBL3764883; LTURM 34; BDBM50147675. CAS No. 1879887-96-3. Molecular formula: C24H18N2O3S. Mole weight: 414.48. | |
| Lucanthone | Lucanthone is orally available thioxanthone-based DNA intercalator and inhibitor of the DNA repair enzyme apurinic-apyrimidinic endonuclease 1 (APEX1 or APE1), with anti-schistosomal and potential antineoplastic activity. Lucanthone intercalates DNA and interferes with the activity of topoisomerases I and II during replication and transcription, thereby inhibiting the synthesis of macromolecules. In addition, this agent specifically inhibits the endonuclease activity of APE1, without affecting its redox activity, resulting in unrepaired DNA strand breaks which may induce apoptosis. Therefore, lucanthone may sensitize tumor cells to radiation and chemotherapy. Furthermore, lucanthone inhibits autophagy through the disruption of lysosomal function. The multifunctional nuclease APE1 is a key component for DNA repair; its expression is often correlated with tumor cell resistance to radio- and chemotherapy. Uses: Schistosomicides. Synonyms: Lucanthonum; 1-{[2-(Diethylamino)ethyl]amino}-4-methyl-9H-thioxanthen-9-one; CCRIS 1106. CAS No. 479-50-5. Molecular formula: C20H24N2OS. Mole weight: 340.48. | |
| Lucatumumab | Lucatumumab is a human anti-CD40 monoclonal antibody. Lucatumumab blocks the interaction of CD40 and its ligand CD40L, inhibiting CD40L-mediated proliferation of normal B cells, CLL cells and non-Hodgkin lymphoma cells. Lucatumumab also mediates antibody-dependent cell-mediated cytotoxicity (ADCC). Synonyms: HCD122. CAS No. 903512-50-5. | |
| Lufepirsen | Lufepirsen is a gap junction alpha-1 protein synthesis reducer. Synonyms: 2'-deoxyguanylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxycytidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxycytidylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxycytidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxycytidine. CAS No. 287122-58-1. Molecular formula: C296H371N112O180P29. Mole weight: 9276.09. | |
| lugdunin | Lugdunin is a novel antibiotic seperated from lugdunensis in human nose. Study showed that it could kill some superbugs. Uses: Antibiotic. Synonyms: (1R,4R,7S,10R,13S,16R,19S)-7-[(1H-indol-3-yl)methyl]-10-(2-methylpropyl)-4,13,16,19-tetra(propan-2-yl)-21-thia-3,6,9,12,15,18,23-heptaazabicyclo[18.2.1]tricosane-2,5,8,11,14,17-hexone. CAS No. 1989698-37-4. Molecular formula: C40H62N8O6S. Mole weight: 783.05. | |
| Lumefantrine b-D-Glucuronide | Lumefantrine b-D-Glucuronide is an indispensable pharmaceutical compound in the study of malaria, exemplifing a glucuronide conjugate derivative of lumefantrine. Synonyms: (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-a-[(dibutylamino)methyl]-9H-fluorene-4-methanol b-D-Glucopyranosiduronic Acid. Molecular formula: C36H40Cl3NO7. Mole weight: 705.06. | |
| Lumefantrine glucuronide - (mixture of diasteromers) | Lumefantrine glucuronide is a complex mixture comprising diastereomers, harnessed within the pharmaceutical domain for the purpose of robustly studying the notorious scourge of malaria. Operating as a potent antimalarial compound, it remarkably displays tremendous efficacy in research of Plasmodium species. Molecular formula: C36H40Cl3NO7. Mole weight: 705.06. | |
| Lumiracoxib Acyl-β-D-glucuronide | Lumiracoxib Acyl-β-D-glucuronide is a metabolite of Lumiracoxib. Synonyms: 1-[2-[(2-Chloro-6-fluorophenyl)amino]-5-methylbenzeneacetate] β-D-Glucopyranuronic Acid. Grades: > 95%. CAS No. 697287-17-5. Molecular formula: C21H21ClFNO8. Mole weight: 469.84. | |
| Lurtotecan | liposomal lurtotecan is a liposome-encapsulated formulation of lurtotecan with antineoplastic activity. Lurtotecan, a semisynthetic analogue of camptothecin, selectively stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex during S phase of the cell cycle, thereby inhibiting religation of topoisomerase I-mediated single-stranded DNA breaks. This ultimately results in an inhibition of DNA replication, inducing double-stranded DNA breakages, obstruction of RNA and protein synthesis and triggering apoptosis. Furthermore, this agent also stimulates degradation of topoisomerase I, likely mediated through ubiquitin-proteasomal pathway. Liposomal delivery of lurtotecan improves its penetration and delivery into tumors while lowering systemic side effects. Synonyms: OSI-221; OSI 221; OSI221; NX211; NX 211; NX-211; (S)-8-ethyl-8-hydroxy-15-((4-methylpiperazin-1-yl)methyl)-11,14-dihydro-2H-[1,4]dioxino[2,3-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-9,12(3H,8H)-dione. CAS No. 149882-10-0. Molecular formula: C28H30N4O6. Mole weight: 518.57. | |
| Lusvertikimab | Lusvertikimab is a humanized monoclonal antibody and interleukin-7 receptor antagonist. Synonyms: OSE-127. CAS No. 2375835-91-7. | |
| LW6 | LW6 inhibits the accumulation of HIF-1alpha and decreases HIF-1alpha protein expression without affecting HIF-1beta expression. LW6 can rescue cardiomyocyte formation in Fgfr1-/- murine embryonic stem cells (mESC). Synonyms: 4-Hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7]dec-1-ylphenoxy)acetyl]amino]-benzoic Acid Methyl Ester. Grades: >98%. CAS No. 934593-90-5. Molecular formula: C26H29NO5. Mole weight: 435.52. | |
| L-Xylonic acid-1,4-lactone | L-Xylonic acid-1,4-lactone is an extraordinary biomedical compound, emerging as a promising solution for studying diverse recalcitrant malignancies and neurodegenerative maladies. Derived proficiently from xylose, it showcases remarkable antioxidant attributes and assumes a pivotal stance in intracellular metabolism. Molecular formula: C5H8O5. Mole weight: 148.11. | |
| L-Xylosamine | L-Xylosamine is a bioactive molecule extensively employed in the biomedical realm assuming a fundamental role when studying a plethora of ailments intertwined with glycosaminoglycan metabolism. Its pivotal function as a precursor augments the biosynthesis of heparan sulfate is a vital constituent within the extracellular matrix. Molecular formula: C5H11NO4. Mole weight: 149.15. | |
| L-Xylose-BSA | | |
| L-Xylulose - Aqueous solution | Cas No. 527-50-4. | |
| LY 134046 | LY 134046 is a centrally active PNMT (phenylethanolamine-N-methyltransferase) inhibitor. It has cardiovascular effects in spontaneously hypertensive rats. Synonyms: LY 134046; LY134046; LY-134046; Lilly 134046; 8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine. Grades: 98%. CAS No. 71274-97-0. Molecular formula: C10H11Cl2N. Mole weight: 216.11. | |
| LY 191704 | LY 191704, a hexahydrobenzoquinolin derivative, has been found to be a human type I steroid 5alpha-reductase inhibitor that could be probably effective in the treatment of Alopecia and Benign prostatic hyperplasia. It was developed by Eli Lilly and had no development reports since 2001. Uses: 5-alpha reductase inhibitors. Synonyms: LY191704; LY-191704; 8-Chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2H)-one. Grades: 98%. CAS No. 146117-78-4. Molecular formula: C14H16ClNO. Mole weight: 249.74. | |
| LY2090314 | LY2090314 is a potent GSK3 inhibitor with antiproliferative activity. It was shown to promote differentiation of intestinal progenitor cells from human iPSCs. Synonyms: LY-2090314; 3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione. Grades: >98%. CAS No. 603288-22-8. Molecular formula: C28H25FN6O3. Mole weight: 512.545. | |
| LY2119620 | LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors. Synonyms: LY2119620; LY 2119620; LY-2119620. Grades: >98%. CAS No. 886047-22-9. Molecular formula: C19H24ClN5O3S. Mole weight: 437.94. | |
| LY2140023 | LY2140023 is a prodrug of LY-404039 and a novel metabotropic glutamate 2/3 receptor agonist peptide prodrug. lt is currently in clinical development as a potential new treatment for schizophrenia. Uses: Ly2140023 was used for the treatment of post-traumatic stress disorder and for the treatment of schizophrenia. Synonyms: Pomaglumetad methionil; LY-2140023; LY 2140023. Grades: 98%. CAS No. 635318-55-7. Molecular formula: C12H18N2O7S2. Mole weight: 366.40. | |
| LY-215891 | LY-215891 shows potent Gram-(+) and Gram-(-) antibacterial activity. Uses: Ly-215891 shows potent gram-(+) and gram-(-) antibacterial activity. Synonyms: LY 215891; LY215891; 7-(((2-Aminothiazol-4-yl)hydroximinoacetyl)amino)-3-chloro-3-cephem-4-carboxylic acid. Grades: 98%. CAS No. 68403-79-2. Molecular formula: C12H10ClN5O5S2. Mole weight: 403.81. | |
| LY2228820 | LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38αMAPK and p38βMAPK were 7 nM and 3 nM, respectively). Synonyms: Ralimetinib; LY2228820; LY 2228820; LY-2228820. Grades: >98%. CAS No. 862505-00-8. Molecular formula: C24H29FN6. Mole weight: 420.53. | |
| LY 2365109 hydrochloride | Cas No. 868265-28-5. | |
| LY2457546 | LY2457546 is a potent and orally bioavailable inhibitor of multiple receptor tyrosine kinases involved in angiogenic and tumorigenic signalling. Synonyms: LY 2457546; LY-2457546. CAS No. 908265-94-1. Molecular formula: C28H20F4N4O. Mole weight: 504.48. | |
| LY 274614 | LY 274614 is a competitive Glutamate receptor antagonist originated by Eli Lilly. It is a promising therapeutic agent for conditions where glutamate plays a role in the pathology of neuronal degeneration. But no development was reported for the treatment of Alzheimer's disease, Epilepsy, Huntington's disease, Neuroprotection and Parkinson's disease yet. Uses: Alzheimer's disease; epilepsy; huntington's disease; neuroprotection; parkinson's disease. Synonyms: LY 274614; LY 274614; LY 274614. (3alpha,4aalpha,6beta,8aalpha)-decahydro-6-(phosphonomethyl)- 3-Isoquinolinecarboxylic acid. Grades: 98%. CAS No. 136109-04-1. Molecular formula: C11H20NO5P. Mole weight: 277.26. | |
| LY 290324 | LY 290324, a quinoline derivative, has been found to be a Leukotriene D4 receptor antagonist that could be probably effective as antiallergic and antiasthmatic agent. It has no development-reported since 1998. Synonyms: LY290324; LY-290324; 5-(2-(1-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)benzyl)indol-7-yl)ethyl)-1H-tetrazole. Grades: 98%. CAS No. 146554-87-2. Molecular formula: C29H24Cl2N6. Mole weight: 527.45. | |
| LY 294002 hydrochloride | LY 294002 hydrochloride is a PI 3-kinase inhibitor with IC50 values of 0.31μM for PI 3-Kβ, 0.73μM for PI 3-Kα, 1.06μM for PI 3-Kδ and 6.60μM for PI 3-K&gamma. It can inhibit proliferation and induce apoptosis in human colon cancer cells. Synonyms: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride. Grades: ≥99% by HPLC. CAS No. 934389-88-5. Molecular formula: C19H17NO3.HCl. Mole weight: 343.81. | |
| LY3039478 | LY3039478 is an orally active inhibitor of Notch and γ-secretase, with an IC50 of 1 nM in most of the tumor cell lines tested. Synonyms: Crenigacestat; N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide; 4,4,4-Trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6,7-dihydro-5H-benzo[d]pyrido[2,3-b]azepin-7-yl)amino)-1-oxopropan-2-yl)butanamide; Butanamide, N-((1S)-2-(((7S)-6,7-dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido(3,2-a)(3)benzazepin-7-yl)amino)-1-methyl-2-oxoethyl)-4,4,4-trifluoro-. Grades: >98%. CAS No. 1421438-81-4. Molecular formula: C22H23F3N4O4. Mole weight: 464.44. | |
| LY-3177833 | LY-3177833 is a selective CDC7 (IC50 = 3.3 nM) and pMCM2 (IC50 = 290nM) inhibitor. It exhibits an antitumor activity in a wide range of cancers. Uses: Antitumor drug. Synonyms: (3R)-3-(5-Fluoro-4-pyrimidinyl)-2,3-dihydro-3-methyl-6-(1H-pyrazol-4-yl)-1H-isoindol-1-one; LY-3177833; LY 3177833; LY3177833. CAS No. 1627696-51-8. Molecular formula: C16H12FN5O. Mole weight: 309.3. | |
| LY-364947 | LY364947 is a selective inhibitor of TGF-β type-I receptor with potential anticancer activity. LY364947 inhibits TGF-β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3). Uses: Reprogramming. Synonyms: LY364947; LY-364947; LY 364947; HTS 466284; HTS466284; HTS-466284. Grades: 98%. CAS No. 396129-53-6. Molecular formula: C17H12N4. Mole weight: 272.31. | |
| LY 43578 | LY 43578 is an aromatase inhibitor. Synonyms: bis(4-chlorophenyl)-pyrimidin-5-ylmethanol; LY 43578; LY 43578; LY 43578. Grades: >98%. CAS No. 26766-35-8. Molecular formula: C17H12Cl2N2O. Mole weight: 331.2. | |
| LY 56110 | LY 56110, a Pyrimidine derivative, is a novel class of nonsteroidal aromatase inhibitor. LY 56110 inhibited ethinamate-induced sleeping time in rats in vivo. Synonyms: 5-[bis(4-chlorophenyl)methyl]pyrimidine; LY 56110; LY-56110; LY56110. Grades: >98%. CAS No. 26766-37-0. Molecular formula: C17H12Cl2N2. Mole weight: 315.2. | |
| LY83583 | LY83583 is an Msp1 inhibitor, a guanylate cyclase inhibitor and a cGMP modulator. LY83583 inhibits soluble guanylate cyclase in human platelets with an IC50 of 2 μM. LY83583 also inhibits leukotriene synthesis in guinea pig lung and rat peritoneal cells with an IC50 of 1.8 μM, and is a noncompetitive inhibitor of glutathione reductase in bovine intestinal mucosa with a Ki of 3 μM. Uses: Enzyme inhibitors. Synonyms: 6-Anilino-5,8-quinolinedione; 6-(Phenylamino)quinoline-5,8-dione; 6-(Phenylamino)-5,8-quinolinedione; 6-Anilinoquinoline-5,8-quinone; 6-(phenylamino)quinoline-5,8-dione. Grades: ≥95%. CAS No. 91300-60-6. Molecular formula: C15H10N2O2. Mole weight: 250.25. | |
| (+)-Lyoniresinol-3a-O-(6-3,5-dimethoxy-4-hydroxybenzoyl)-b-D-glucopyranoside | | |
| (+)-Lyoniresinol-3a-O-(6-3-methoxy-4-hydroxybenzoyl)-b-D-glucopyranoside | (+)-Lyoniresinol-3a-O-(6-3-methoxy-4-hydroxybenzoyl)-b-D-glucopyranoside is a naturally occurring compound, sought after in the biomedical industry for its noteworthy capacity to act against tumors and inflammation. Research indicates that this compound has shown efficacy in thwarting the proliferation of human lung cancer cells and holds promise in the treatment of other malignancies. Moreover, it has demonstrated the ability to forestall the release of pro-inflammatory cytokines, and thus holds prospects for use in alleviating inflammatory disorders. | |
| M 1145 | M 1145 is a selective and potent galanin receptor 2 (GAL2) agonist with Ki value of 6.55 nM and EC50 value of 38 nM. It has an additive effect on the signal transduction of galanin. Synonyms: M 1145; M1145; M-1145. CAS No. 1172089-00-7. Molecular formula: C128H205N37O32. Mole weight: 2774.26. | |
| M2N12 | M2N12 is a potent and selective inhibitor of cell division cycle 25C protein phosphatase (Cdc25C) with IC50 of 0.09 ?μM. M2N12 exhibits anti-tumor activity. CAS No. 2376577-06-7. Molecular formula: C20H16ClN5O2. Mole weight: 393.83. | |
| M617 | M617 is a chimeric peptide that acts as a selective galanin GAL1 receptor agonist with Ki values of 0.23 and 5.71 nM for GAL1 and GAL2 receptors respectively. It enhances food consumption in rats following i.c.v. administration and reduces CAP-induced inflammatory pain. Synonyms: M617; M 617; M-617; Galanin(1-13)-Gln14-bradykinin(2-9)amide. CAS No. 860790-38-1. Molecular formula: C112H161N29O28. Mole weight: 2361.68. | |
| M7824 | M7824 is a bifunctional anti-PD-L1/TGFβ Trap fusion protein that comprises the extracellular domain of human TGFβRII (TGFβ Trap) linked to the C-terminus of human anti-PD-L1 heavy chain (αPD-L1). M7824 can be used in the treatment of various cancers. Synonyms: MSB0011395C. | |
| Macimorelin | Macimorelin (also known as AEZS-130, EP-1572) is a novel synthetic small molecule, acting as a ghrelin agonist, that is orally active and stimulates the secretion of growth hormone (GH). Based on results of Phase 1 studies, AEZS-130 has potential applications for the treatment of cachexia, a condition frequently associated with severe chronic diseases. In addition to the therapeutic application, a Phase 3 trial with AEZS-130 as a diagnostic test for growth hormone deficiencies in adults has been completed. Synonyms: AEZS-130; AEZS 130; AEZS130; EP-1572; EP1572; EP 1572; JMV 1843; JMV-1843; 2-amino-N-((R)-1-(((R)-1-formamido-2-(1H-indol-3-yl)ethyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-2-methylpropanamide. Grades: 98%. CAS No. 381231-18-1. Molecular formula: C26H30N6O3. Mole weight: 474.56. | |
| Mafosfamide | Mafosfamide is an oxazaphosphorine (cyclophosphamide-like) alkylating agent under investigation as a chemotherapeutic. Uses: Adjuvants, immunologic. Synonyms: Z-7557; Z7557; Z 7557; Mafosfamid. CAS No. 88859-04-5. Molecular formula: C9H19Cl2N2O5PS2. Mole weight: 401.25. | |
| Magrolimab | Magrolimab is a humanized anti-CD47 monoclonal antibody that selectively binds to CD47 expressed on tumor cells and blocks the interaction of CD47 with its ligand signal regulatory protein alpha (SIRPa), a protein expressed on phagocytic cells. Synonyms: anti-CD47; Hu5F9-G4. CAS No. 2169232-81-7. | |
| MAIT 203 | MAIT 203 inhibits interaction of APC and Asef (RhoGEF4). It also inhibits colorectal cancer cell migration and invasion in vitro. Synonyms: MAIT 203; MAIT203; MAIT-203; N- [ (Benzyl oxy) carbonyl ] -L-alanyl glycyl -L- α -glutamyl -L-alanyl -3-cyclopentyl -L-alanyl -L-tyrosyl -L- α -glutamyl glycyl glycyl glycyl glycyl glycyl -L-arginyl -L-lysyl -L-lysyl -L-arginyl -L-arginyl -L-glutaminyl -L-arginyl -L-arginyl -L-argininamide. Molecular formula: C106H177N43O29. Mole weight: 2517.83. | |
| Maltooligosaccharides | | |
| Maltopyranosyl-CTP | Maltopyranosyl-CTP is a distinctive derivative of Cytidine triphosphate (CTP) assuming an indispensable role in multifarious cellular processes. Its paramount significance lies in orchestrating nucleic acid synthesand facilitating energy transfer. Synonyms: 2-Deoxycytidine 5-triphosphate-a-D-maltopyranoside sodium salt. Molecular formula: C21H32N2Na3O24P3. Mole weight: 858.37. | |
| Maltosyl-ascorbic acid | | |
| Malvidin 3,5-diglucoside | Malvidin 3,5-diglucoside is a significant compound present in diverse fruits and vegetables, exhibiting remarkable antioxidant attributes and has been subject to extensive investigation regarding its prospective role in averting chronic ailments such as cancer, cardiovascular diseases and neurodegenerative disorders. Synonyms: Malvoside; Malvidin chloride 3,5-diglucoside; Malvin(chloride). CAS No. 16727-30-3. Molecular formula: C29H35O17Cl. Mole weight: 691.03. | |
| Malvidin-3-galactoside chloride | Malvidin-3-galactoside chloride is a profoundly influential compound widely employed in the biomedical industry due to its immense therapeutic potential. With well-established acclaim for its formidable antioxidant prowess and remarkable anti-inflammatory attributes, this product showcases exceptional efficacy in combating an extensive range of afflictions including cancer, cardiovascular disorders, and neurodegenerative conditions. Synonyms: Primulin. CAS No. 30113-37-2. Molecular formula: C23H25ClO12. Mole weight: 528.9. | |
| Malvidin 3-glucoside | Cas No. 7228-78-6. | |
| Mannoheptulose | Mannoheptulose is a biochemical compound widely used in the biomedicine industry. Derived from mannose, it possesses potential therapeutic applications in treating diabetes and obesity. Mannoheptulose works by inhibiting the enzyme glucokinase, playing a crucial role in cellular glucose metabolism. Its efficacy and safety profiles make it a promising candidate for further research and development in managing metabolic disorders. CAS No. 654-29-5. Molecular formula: C7H14O7. Mole weight: 210.182. | |
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