BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| MLN-9708 | ixazomib is an orally bioavailable second generation proteasome inhibitor (PI) with potential antineoplastic activity. Ixazomib inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome, which results in an accumulation of unwanted or misfolded proteins; disruption of various cell signaling pathways may follow, resulting in the induction of apoptosis. Compared to first generation PIs, second generation PIs may have an improved pharmacokinetic profile with increased potency and less toxicity. Proteasomes are large protease complexes that degrade unneeded or damaged proteins that have been ubiquinated. Synonyms: Ixazomib; MLN-9708; MLN 9708; MLN9708. CAS No. 1201902-80-8. Molecular formula: C20H23BCl2N2O9. Mole weight: 517.12. |  |
| MLS-573151 | MLS-573151 is a specific and cell-permeable inhibitor of Cdc42, a GTPase of the Rho family. Synonyms: 4-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide. Grades: ≥98%. CAS No. 10179-57-4. Molecular formula: C21H19N3O2S. Mole weight: 377.5. | |
| m-Methoxytopolin-9-glucoside | m-Methoxytopolin-9-glucoside is an intricate and potent bioactive compound, used for studying a myriad of afflictions including cancer, inflammation and neurodegenerative disorders. Synonyms: 6-(3-Methoxybenzylamino)-9-b-Dglucopyranosylpurine. CAS No. 1226978-21-7. Molecular formula: C19H23N5O6. Mole weight: 417.42. | |
| MMPIP | MMPIP hydrochloride is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits agonist-induced intracellular calcium mobilization and cAMP accumulation (IC50 = 26 and 610 nM). MMPIP also exhibits intrinsic activity and acts as an inverse agonist. Synonyms: 6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one hydrochloride. Grades: ≥98% by HPLC. CAS No. 479077-02-6. Molecular formula: C19H15N3O3. Mole weight: 333.3. | |
| MN-201 | MN-201 is an orally administered vitamin D5 analog for the treatment of cancer. MN-201 is the first synthetic vitamin D5 receptor ligand (VDRL) to be advanced into clinical trials for a variety of cancers including breast, prostate and colon cancers. In preclinical studies, MN-201 demonstrated broad anti-tumor activity in cancer cells. In animal models, oral administration of MN-201 also resulted in anti-tumor activity including tumor regression in xenograft models of major solid tumor types. In contrast to treatment with other vitamin D(3) analogs and the naturally occurring vitamin D hormone, calcitriol, favorable anticancer effects with MN-201 were observed in the absence of significantly raised calcium levels. Synonyms: MN 201; MN201; 1alpha-hydroxy-24-ethylcholecalciferol. CAS No. 187935-17-7. Molecular formula: C29H48O2. Mole weight: 428.70. | |
| MNI 137 | MNI 137 is a noverl allosteric modulator of regulating CNS function through the group II metabotropic glutamate receptors. MNI 137 is a selective negative modulator of group II mGlu receptors (IC50 = 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization), without effect at mGlu1, mGlu4, mGlu5 or mGlu8 receptors in a calcium mobilization assay. Synonyms: 4-(8-Bromo-2,3-dihydro-2-oxo-1H-1,5-benzodiazepin-4-yl)-2-pyridinecarbonitrile; MNI-137; MNI 137; MNI137. Grades: ≥98% by HPLC. CAS No. 946619-21-2. Molecular formula: C15H9BrN4O. Mole weight: 341.16. | |
| MNI-caged-D-aspartate | MNI-caged-D-aspartate, a photolabelled derivative of D-aspartate, is photolyzed by UV light with a quantum efficiency of 0.09 at pH 7.4. MNI-caged-D-aspartate is agonist at NMDA receptors and EAAT substrate. Synonyms: (R)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-γ-oxo-1H-indole-1-butanoic acid. Grades: ≥98% by HPLC. CAS No. 845555-94-4. Molecular formula: C13H15N3O6. Mole weight: 309.27. | |
| MNI-caged-L-glutamate | MNI-caged-L-glutamate, a new caged neuroactive amino acid, rapidly and efficiently releases glutamate when photolysed (300-380 nm excitation). MNI-caged-L-glutamate uses 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. Synonyms: (S)-α-Amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid. Grades: ≥98% by HPLC. CAS No. 295325-62-1. Molecular formula: C14H17N3O6. Mole weight: 323.3. | |
| MNS | MNS (3,4-methylenedioxy-beta-nitrostyrene) prevented platelet aggregation caused by various stimulators, and this action was accompanied by inhibition of tyrosine kinases. Synonyms: 3,4-Methylenedioxy-beta-nitrostyrene; Syk Inhibitor III; NSC 170724; 5-(2-Nitrovinyl)benzodioxole. Grades: 98%. CAS No. 1485-00-3. Molecular formula: C9H7NO4. Mole weight: 193.16. | |
| Moexipril acyl-b-D-glucuronide | Moexipril acyl-b-D-glucuronide is an essential compound deployed within the biomedical sector, serving as an active metabolite of the revered antihypertensive medication, moexipril. Its multifaceted prowess extends to the research of disorders encompassing hypertension with the suppression of angiotensin-converting enzyme (ACE). Synonyms: (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenyl-D5-propyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylate b-D-glucopyranuronic acid. Molecular formula: C33H42N2O13. Mole weight: 674.69. | |
| Moexiprilat acyl D-glucuronide | | |
| Mogroside Ive | Mogroside Ive is extracted from the fruit of Siraitia grosvenorii Swingle. Synonyms: (24R)-3β-(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyloxy)-24-(2-O-β-D-glucopyranosyl-β-D-glucopyranosyloxy)cucurbita-5-ene-11α,25-diol; Mogroside IV-E. Grades: >98%. CAS No. 88915-64-4. Molecular formula: C54H92O24. Mole weight: 1125.3. | |
| moiramide B | Moiramide B is an antibacterial drug that competitively inhibits malonyl-CoA (Ki = 5 nM), which is broadly conserved in bacteria. Synonyms: (2E,4E)-Hexa-2,4-dienoic acid {(S)-2-[(S)-2-methyl-1-((3R,4S)-4-methyl-2,5-dioxo-pyrrolidine-3-carbonyl)-propylcarbamoyl]-1-phenyl-ethyl}-amide. CAS No. 155233-31-1. Molecular formula: C25H31N3O5. Mole weight: 453.53. | |
| Monalizumab | Monalizumab is a first-in-class immune checkpoint inhibitor that targets Natural Killer Group 2A (NKG2A). Monalizumab increased degranulation and IFN-γ production by NKG2A+ NK cell against HLA-E+ target cells, thereby promoting NK cell effector functions. Synonyms: IPH2201. CAS No. 1228763-95-8. | |
| Monastrol | Monastrol is a kinesin Eg5 inhibitor. Induction of apoptosis by monastrol is independent of the spindle checkpoint. Monastrol binds to the KSP-ADP complex, forming a KSP-ADP-monastrol ternary complex, which cannot bind to microtubules productively and cannot undergo further ATP-driven conformational changes. Uses: Antimitotic agents. Synonyms: DL-Monastrol; (S)-Monastrol; (+/-)-Monastrol; 4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic Acid Ethyl Ester. CAS No. 254753-54-3. Molecular formula: C14H16N2O3S. Mole weight: 292.36. | |
| Monogalactosyldiacylglycerol | Monogalactosyldiacylglycerol is a vital component in the biomedical industry used extensively in the formulation of pharmaceuticals. It exhibits anti-inflammatory properties, making it an ideal candidate for developing drugs targeting inflammatory conditions like arthritand asthma. Synonyms: 1,2-Diacyl-3-O-b-D-galactosyl-sn-glycerol; MGDG. Molecular formula: C45H74O10. Mole weight: 775.06. | |
| Montelukast-Acyl-Glucuronide | An impurity of Montelukast Sodium, which is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Synonyms: 1-O-[2-[1-[[ (R) -1-[3-[ (E) -2- (7-Chloroquinolin-2-yl) ethenyl]phenyl]-3-[2- (1-methyl-1-hydroxyethyl) phenyl]propylthio]methyl]cyclopropan-1-yl]acetyl]-beta-D-glucopyranuronic acid. Grades: >95%. CAS No. 188717-17-1. Molecular formula: C41H44ClNO9S. Mole weight: 762.31. | |
| Mosunetuzumab | Mosunetuzumab is an anti-CD20 and anti-CD3 bispecific monoclonal antibody approved for the treatment of follicular lymphoma. It redirects T cells to engage and eliminate malignant B cells. Synonyms: BTCT-4465A; Lunsumio. CAS No. 1905409-39-3. | |
| Motexafin gadolinium | Motexafin gadolinium is a synthetic metallotexaphyrin with radiosensitizing and chemosensitizing properties. Motexafin gadolinium accumulates in tumor cells preferentially due to their increased rates of metabolism, generating reactive oxygen species (ROS) intracellularly and lowering the tumor cell apoptotic threshold to ionizing radiation and chemotherapy. Uses: Antineoplastic agents. Synonyms: PCI 0120; PCI-0120; PCI0120; API-GP 3; Gd texaphyrin; Gd-Texgadolinium; texaphyrin; Gd (III) Texaphryin; gadolinium texaphyrin; Gd (III) Texaphryin. CAS No. 246252-06-2. Molecular formula: C52H72GdN5O14. Mole weight: 1148.41. | |
| Motexafin lutetium | Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects. Uses: Photosensitizing agents. Synonyms: Antrin; Lu texaphyrin; Lu-Tex; Lutetium texaphyrin; Lutrin; Optrin; PCI 0123; PCI-0123; PCI0123. CAS No. 246252-04-0. Molecular formula: C52H72LuN5O14. Mole weight: 1166.14. | |
| Moxifloxacin acyl D-glucuronide | Moxifloxacin acyl D-glucuronide is a pivotal pharmaceutical compound extensively employed within the biomedical domain, representing a derivative of Moxifloxacin, a revered fluoroquinolone antibiotic. Manifesting itself as an active metabolite, this particular product is used for the analysis of intricate interplay of pharmacokinetics and efficacy of Moxifloxacin and proficiently studying an array of bacterial infections, including pneumonia, bronchitis and sinusitis. | |
| Moxifloxacin acyl glucuronide | An impurity of Moxifloxacin, which is fourth generation antibacterial agent. Synonyms: 1-[1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylate] b-D-glucopyranuronic acid. Grades: > 95%. CAS No. 733002-61-4. Molecular formula: C27H32FN3O10. Mole weight: 577.56. | |
| MPPG | MPPG is a potent antagonist of L-AP4-induced effects in rat spinal cord, thalamic and hippocampal neurons, showing selectivity over (1S,3S)-ACPD-induced effects. MPPG should be useful in determining the roles of group II and III mGluRs in the central nervous system. Synonyms: (RS)-α-Methyl-4-phosphonophenylglycine. CAS No. 169209-65-8. Molecular formula: C9H12NO5P. Mole weight: 245.17. | |
| MPT0B098 | MPT0B098 is a potent microtubule inhibitor through binding to the colchicine-binding site of tubulin. MPT0B098 is active against the growth of various human cancer cells, including chemoresistant cells with IC50 values ranging from 70 to 150 nmol/L. MPT0B098 arrests cells in the G2-M phase and subsequently induces cell apoptosis. In addition, MPT0B098 effectively suppresses VEGF-induced cell migration and capillary-like tube formation of HUVECs. Distinguished from other microtubule inhibitors, MPT0B098 not only inhibited the expression levels of HIF-1α protein but also destabilized HIF-1α mRNA. The mechanism of causing unstable of HIF-1α mRNA by MPT0B098 is through decreasing RNA-binding protein, HuR, translocation from the nucleus to the cytoplasm. Notably, MPT0B098 effectively suppresses tumor growth and microvessel density of tumor specimens in vivo. Taken together, our results provide a novel mechanism of inhibiting HIF-1α of a microtubule inhibitor MPT0B098. MPT0B098 is a promising anticancer drug candidate with potential for the treatment of human malignancies. Synonyms: MPT 0B098; MPT-0B098; 1-(4-methoxyphenylsulfonyl)-7-(pyridin-4-yl)indoline. CAS No. 1254363-89-7. Molecular formula: C20H18N2O3S. Mole weight: 366.43. | |
| MPT0B214 | MPT0B214 is a novel and potent microtubule inhibitor with potential anticancer activity. MPT0B214 inhibited tubulin polymerization through strongly binding to the tubulin's colchicine-binding site and had cytotoxic activity in a variety of human tumor cell lines. After treatment with MPT0B214, KB cells were arrested in the G2-M phase before cell death occurred, which were associated with upregulation of cyclin B1, dephosphorylation of Cdc2, phosphorylation of Cdc25C and elevated expression of the mitotic marker MPM-2. Furthermore, the compound induced apoptotic cell death through mitochondria/caspase 9-dependent pathway. Notably, several KB-derived multidrug-resistant cancer cell lines were also sensitive to MPT0B214 treatment. Synonyms: MPT0B214; MPT 0B214; MPT-0B214. Grades: 98%. CAS No. 1215208-65-3. Molecular formula: C20H20N2O5. Mole weight: 368.38. | |
| MPT0E028 | MPT0E028 is a novel N-hydroxyacrylamide-derived HDAC inhibitor, inhibited human colorectal cancer HCT116 cell growth in vitro and in vivo. The results of NCI-60 screening showed that MPT0E028 inhibited proliferation in both solid and hematological tumor cell lines at micromolar concentrations, and was especially potent in HCT116 cells. MPT0E028 had a stronger apoptotic activity and inhibited HDACs activity more potently than SAHA, the first therapeutic HDAC inhibitor proved by FDA. In vivo murine model, the growth of HCT116 tumor xenograft was delayed and inhibited after treatment with MPT0E028 in a dose-dependent manner. Based on in vivo study, MPT0E028 showed stronger anti-cancer efficacy than SAHA. No significant body weight difference or other adverse effects were observed in both MPT0E028-and SAHA-treated groups. Taken together, our results demonstrate that MPT0E028 has several properties and is potential as a promising anti-cancer therapeutic drug. Synonyms: 3-(1-(Benzenesulfonyl)-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide; MPT-0E028; MPT 0E028. Grades: 98%. CAS No. 1338320-94-7. Molecular formula: C17H16N2O4S. Mole weight: 344.38. | |
| MRK003 | MRK003 is a γ-secretase inhibitor exhibits promising in vitro pre-clinical activity in multiple myeloma and non-Hodgkin's lymphoma. MRK003 treatment induced caspase-dependent apoptosis and inhibited proliferation of MM and NHL cell lines and patient cells. Examination of signaling events after treatment showed time-dependent decrease in levels of the notch intracellular domain, Hes1 and c-Myc. MRK003 downregulated cyclin D1, Bcl-Xl and Xiap levels in NHL cells and p21, Bcl-2 and Bcl-Xl in MM cells. In addition, MRK003 caused an upregulation of pAkt, indicating crosstalk with the PI3K/Akt pathway. Uses: Gamma secretase inhibitors and modulators. Synonyms: MRK-003; MRK 003. CAS No. 623165-93-5. Molecular formula: C25H31F6N3O2S. Mole weight: 551.59. | |
| MRS 1523 | MRS 1523 is a potent and selective adenosine A3 receptor antagonist (Ki= 18.9 nM for human A3R). Uses: Purinergic p1 receptor antagonists. Synonyms: MRS1523; MRS 1523; MRS-1523. Propyl 6-ethyl-5-ethylsulfanylcarbonyl-2-phenyl-4-propylpyridine-3-carboxylate. Grades: 98%. CAS No. 212329-37-8. Molecular formula: C23H29NO3S. Mole weight: 399.55. | |
| MRS 1706 | MRS 1706 is a potent and selective A2B inverse agonist. Uses: Adenosine a2 receptor antagonists. Synonyms: MRS1706; MRS 1706; MRS-1706. N-(4-Acetylphenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]acetamide. CAS No. 264622-53-9. Molecular formula: C27H29N5O5. Mole weight: 503.56. | |
| MRS 1754 | MRS 1754 is a selective A2B antagonist. Synonyms: MRS1754; MRS-1754; MRS 1754; N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide. CAS No. 264622-58-4. Molecular formula: C26H26N6O4. Mole weight: 486.52. | |
| MS-073 | MS-073 is a Type II DNA topoisomerase inhibitor under the development of Nihon Schering. MS-073 can overcome MDR in vitro and in vivo compare to verapamil. MS-073 at 0.1 mM can almost completely reverse in vitro resistance to vincristine in vincristine-resistant P388 cells. MS-073 can also reverse in vitro vincristine, adriamycin, etoposide, and actinomycin D resistance in adriamycin-resistant human myelogenous leukemia K562 cells. MS-073 reverses MDR through competitively inhibiting drug binding to P-glycoprotein. Treatment for cancer was discontinued. Uses: Cancer. Synonyms: MS-073; MS073; MS 073; CP-162398; CP-162398; CP 162398; CP162398; 1-(Quinolin-5-yloxy)-3-[4-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten)-5-yl]piperazin-1-yl]-2-propanol. Grades: 98%. CAS No. 129716-45-6. Molecular formula: C31H33N3O2. Mole weight: 479.62. | |
| MSC-2032964A | MSC-2032964A acts as a selective apoptosis signal-regulating kinase 1(ASK1) inhibitor suppressing neuroinflammation with IC50 value of 93 nM in mice. It blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. It suppresses neuroinflammation in a mouse EAE model. It is orally bioavailable and brain penetrant. Synonyms: MSC2032964A; MSC 2032964A; N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide; N-(5-(cyclopropylamino)-7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide; 3-Pyridinecarboxamide, N-[5-(cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-. Grades: >98%. CAS No. 1124381-43-6. Molecular formula: C16H13F3N6O. Mole weight: 362.32. | |
| MS-PPOH | MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes. It potently inhibits two CYP450 epoxygenases CYP2C9 and CYP2C11 (IC50 = 11-16 μM). Synonyms: N-methylsulfonyl-6-(2-propargyloxyphenyl)hexanamide. Grades: ≥98%. CAS No. 206052-02-0. Molecular formula: C16H21NO4S. Mole weight: 323.4. | |
| MT477 | MT477 is PKC-α inhibitor. MT477 interfered with PKC activity as well as phosphorylation of Ras and ERK1/2 in H226 human lung carcinoma cells. It also induced poly-caspase-dependent apoptosis. MT477 had a dose-dependent (0.006 to 0.2 mM) inhibitory effect on cellular proliferation of H226, MCF-7, U87, LNCaP, A431 and A549 cancer cell lines as determined by in vitro proliferation assays. Synonyms: MT 477; MT-477; tetramethyl 6'-[(2,5-dioxopyrrolidin-1-yl)acetyl]-7'-methoxy-5',5'-dimethyl-5',6'-dihydrospiro[1,3-dithiole-2,1'-thiopyrano[2,3-c]quinoline]-2',3',4,5-tetracarboxylate. CAS No. 328069-91-6. Molecular formula: C31H30N2O12S3. Mole weight: 718.77. | |
| m-Topolin-9-glucoside | m-Topolin-9-glucoside is a powerful compound with potent anti-inflammatory attributes, warranting its utilization in the research of afflictions like rheumatoid arthritand inflammatory bowel disease. Synonyms: 6-(3-hydroxybenzylamino)-9-b-D-glucopyranosyl purine. CAS No. 179528-30-4. Molecular formula: C18H21N5O6. Mole weight: 403.39. | |
| MTPG | MTPG is a group II/group III metabotropic glutamate receptor antagonist. MTPG inhibited the induction of ischemia tolerance indicating the involvement of mGluR2/3 in the induction of the protective mechanism. Synonyms: (RS)-α-Methyl-4-tetrazolylphenylglycine. CAS No. 169209-66-9. Molecular formula: C10H11N5O2. Mole weight: 233.23. | |
| Mucic acid | Mucic acid (CAS# 526-99-8) is used to study functionalization of onodisperse magnetic nanoparticles by organic acid and polymers. Synonyms: (2S,3R,4S,5R)-2,3,4,5-tetrahydroxyhexanedioic acid. Grades: 98 %. CAS No. 526-99-8. Molecular formula: C6H10O8. Mole weight: 210.14. | |
| muco-Inositol | muco-Inositol is an indispensable biomedical substance, manifesting its paramount significance in the intricate regulations of insulin signaling cascades, thus exhibiting advantageous prospects in the research of diabetes. CAS No. 488-55-1. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| Mupadolimab | Mupadolimab is a humanized anti-CD73 monoclonal antibody that inhibits production of immunosuppressive adenosine in the tumour microenvironment, binding to CD73 on B cells leads to their activation (including increased antibody production). Mupadolimab was developed for the treatment of head and neck cancer, and NSCLC. Synonyms: CPI-006; CPI 006; CPI006. CAS No. 2451856-97-4. | |
| Muramic acid hydrate | Muramic acid hydrate is an intriguing compound serving as a pivotal constituent within bacterial peptidoglycan. It assumes an indispensable position in the exploration of antibiotics and the intricate mechanisms of drug resistance. CAS No. 1114-41-6. Molecular formula: C9H17NO7 H2O. Mole weight: 269.25. | |
| Muromonab | Muromonab is a monoclonal antibody targeting CD3 receptor. Muromonab can be used as an immunosuppressant drug that reduces the natural immunity of patients who receive organ transplants. CAS No. 140608-64-6. | |
| Muscarine tosylate | Muscarine tosylate is an invaluable compound within the realm of pharmacology, aiding in the research of various afflictions rooted in disruptions of the parasympathetic nervous system. Manifesting its efficacy as a cholinergic receptor agonist, this compound predominantly directs its actions towards the muscarinic receptors. | |
| Muzolimine | Muzolimine is a pyrazole and high-ceiling loop diuretic with long duration and high capacity of action. It was used for kidney failure and hypertension but was withdrawn worldwide because of severe neurological effects. Uses: Muzolimine was used for kidney failure and hypertension. Synonyms: Edrul; Muzolimina; BAY G 2821; 3-amino-1-(1-(3,4-dichlorophenyl)ethyl)-1H-pyrazol-5(4H)-one. Grades: 98%. CAS No. 55294-15-0. Molecular formula: C11H11Cl2N3O. Mole weight: 272.13. | |
| MV151 | MV151 is a fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. MV151 specifically targets all active subunits of the proteasome and immunoproteasome in living cells, allowing for rapid and sensitive in-gel detection. The inhibition profile of a panel of commonly used proteasome inhibitors could be readily determined by MV151 labeling. Administration of MV151 to mice allowed for in vivo labeling of proteasomes, which correlated with inhibition of proteasomal degradation in the affected tissues. This probe can be used for many applications ranging from clinical profiling of proteasome activity, to biochemical analysis of subunit specificity of inhibitors, and to cell biological analysis of the proteasome function and dynamics in living cells. Synonyms: MV-151; MV 151; MV151; Bodipy TMR-Ahx(3)L(3)VS. Grades: 98%. CAS No. 945611-88-1. Molecular formula: C59H91BF2N8O9S. Mole weight: 1137.27. | |
| Mycaminose | Mycaminose is an exceptional biomedical compound, emerging as a resolute solution tailored to study the ailment of cardiovascular diseases and diabetes. Synonyms: 3,6-Dideoxy-3-(dimethylamino)-D-glucose; 3,6-Didesoxy-3-(dimethylamino)-β-D-glucopyranose; β-D-Glucopyranose, 3,6-dideoxy-3-(dimethylamino)-; 3-(Dimethylamino)-3,6-dideoxy-D-glucose; 3-dimethylamino-3,6-dideoxy-β-D-glucopyranose. Grades: ≥95%. CAS No. 519-21-1. Molecular formula: C8H17NO4. Mole weight: 191.22. | |
| MYCi361 | MYCi361 is a MYC inhibitor with a Kd of 3.2 μM when combined with MYC. It can inhibit tumor growth and enhance anti-PD1 immunotherapy. Synonyms: 6-((4-Chlorobenzyl)Oxy)-3-(1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)-3',5'-Bis(Trifluoromethyl)-[1,1'-Biphenyl]-2-Ol; SCHEMBL21786589; BCP34061; EX-A3659. Grades: 98%. CAS No. 2289690-31-7. Molecular formula: C26H16ClF9N2O2. Mole weight: 594.9. | |
| MYCi975 | MYCi975 is an orally active MYC inhibitor that can disrupt the MYC/MAX interaction, promote MYC T58 phosphorylation and MYC degradation, and impair MYC-driven gene expression. It exhibits strong anti-tumor efficacy and good tolerance, increases tumor immune cell infiltration, and makes tumors sensitive to anti-PD1 immunotherapy. Synonyms: 4'-Chloro-6-((4-Chlorobenzyl)Oxy)-3-(1-Methyl-3-(Trifluoromethyl)-1H-Pyrazol-5-Yl)-3'-(Trifluoromethyl)-[1,1'-Biphenyl]-2-Ol. Grades: 98%. CAS No. 2289691-01-4. Molecular formula: C25H16Cl2F6N2O2. Mole weight: 561.3. | |
| Mycophenolic Acid Acyl Glucoside | An impurity of Mycophenolic which inhibits an enzyme needed for the growth of T cells and B cells. Synonyms: 1-[(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoate] b-D-glucopyranose. Grades: > 95%. CAS No. 344562-78-3. Molecular formula: C23H30O11. Mole weight: 482.48. | |
| Mycophenolic acid b-D-glucuronide | Mycophenolic acid b-D-glucuronide is a vital tool in the biomedical industry commonly used as an immunosuppressive compound to study transplant rejection after kidney, heart, or liver transplantation. This product effectively inhibits T-cell and B-cell proliferation. Synonyms: mycophenolic acid glucuronide; 31528-44-6; Mycophenolic acid glucosiduronate; Mycophenolic acid 7-O-glucuronide; 54TS5J9T0K; Mycophenolic Acid beta-D-Glucuronide; (2S,3S,4S,5R,6S)-6-[[5-[(E)-5-carboxy-3-methylpent-2-enyl]-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-4-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid; UNII-54TS5J9T0K; Mycophenolic Acid-d3 Glucuronide; 31528-44-6 (unlabeled); BYFGTSAYQQIUCN-HGIHDBQLSA-N; DTXSID401043388; Mycophenolic Acid ?-D-Glucuronide; Mycophenolic Acid-d3 Glucosiduronate; Mycophenolic acid beta -D-glucuronide; MS-29220; Mycophenolic Acid-d3 beta -D-Glucuronide; HY-137301; CS-0137607; (2S,3S,4S,5R,6S)-6-((5-((E)-5-Carboxy-3-methylpent-2-en-1-yl)-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-4-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid.BETA.-D-GLUCOPYRANOSIDURONIC ACID, 5-((2E)-5-CARBOXY-3-METHYL-2-PENTEN-1-YL)-1,3-DIHYDRO-6-METHOXY-7-METHYL-3-OXO-4-ISOBENZOFURANYL. CAS No. 31528-44-6. Molecular formula: C23H28O12. Mole weight: 496.46. | |
| Mycophenolic Acid Phenolic beta-D-Glucoside | An impurity of Mycophenolic which inhibits an enzyme needed for the growth of T cells and B cells. Synonyms: (4E)-6-[4-(b-D-Glucopyranosyloxy)-1,3-dihydro-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl]-4-methyl-4-hexenoic acid. Grades: > 95%. CAS No. 55533-52-3. Molecular formula: C23H30O11. Mole weight: 482.48. | |
| myo-Inositol 1,2,3,4,6-pentakisphosphate | myo-Inositol 1,2,3,4,6-pentakisphosphate, a bioactive molecule, has proved its worth in the biomedical industry as an effective cancer cell growth inhibitor with potential for treating hepatocellular and colorectal cancers. This powerful compound inhibits ROCK signaling pathways, which are implicated in cancer cell migration and invasion, making it an important target for new drug development. Researchers also believe that myo-Inositol 1,2,3,4,6-pentakisphosphate could help to regulate glucose metabolism, opening up possibilities for novel diabetes treatments. Synonyms: InsP5. CAS No. 861922-14-7. Molecular formula: C6H17O21P5. Mole weight: 580.06. | |
| myo-Inositol 1,2,3,5,6-pentakisphosphate | myo-Inositol 1,2,3,5,6-pentakisphosphate is a prominent inositol polyphosphate widely employed in the biomedical sector, exhibiting significant intricacy in signal transduction pathways and cellular mechanisms. Its pivotal function as a modulator of intracellular calcium levels aids in scientific research, particularly in relation to cancer, diabetes and neurodegenerative ailments. Synonyms: InsP5. CAS No. 26326-85-2. Molecular formula: C6H17O21P5. Mole weight: 580.06. | |
| myo-Inositol 1,2,4,5,6-pentakisphosphate | myo-Inositol 1,2,4,5,6-pentakisphosphate is a signaling molecule used for biomedical research of cardiovascular adversaries and the insidious threats of diabetes. Synonyms: InsP5. Molecular formula: C6H17O21P5. Mole weight: 580.06. | |
| myo-Inositol 2,3,4,5,6-pentakisphosphate decasodium salt | Introducing myo-Inositol 2,3,4,5,6-pentakisphosphate decasodium salt is a profoundly significant biochemical compound extensively employed in the biomedical realm. Exhibiting its prowess as a potent intracellular messenger, this compound plays a pivotal role in the intricate regulation of a multitude of physiological processes. It is involved in the research of manifold maladies, encompassing cancer, diabetes and neurodegenerative disorders. Synonyms: InsP5. Molecular formula: C6H7Na10O21P5. Mole weight: 799.87. | |
| Myrsinoic acid A | Myrsinoic acid A is an anti-chronic inflammatory agent that is also a DNA polymerase λ-specific inhibitor. Synonyms: 3-Geranyl-4-hydroxy-5-(3'-methyl-2'-butenyl)benzoic acid. CAS No. 135743-12-3. Molecular formula: C22H30O3. Mole weight: 342.47. | |
| N106 | N106 is an activator of SUMO-activating enzyme, E1 ligase. It can improve ventricular function in animal models. Synonyms: N106; N 106; N-106; 4-Methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl-2-benzothiazolamine. Grades: ≥98% by HPLC. CAS No. 862974-25-2. Molecular formula: C17H14N4O3S. Mole weight: 354.38. | |
| N1-a-L-Arabinopyranosylamino-guanidine HNO3 | N1-a-L-Arabinopyranosylamino-guanidine HNO3, a biomedical compound, exhibits its crucial role in treating diverse ailments. Its remarkable efficacy lies in its ability to suppress targeted enzymatic functions, thereby exhibiting promise in impeding the advancement of select cancers and autoimmune disorders. CAS No. 109853-80-7. Molecular formula: C6H14N4O4 HNO3. Mole weight: 269.21. | |
| N-1-b-D-Arabinopyranosylamino guanidine HNO3 | N-1-b-D-Arabinopyranosylamino guanidine HNO3, a newly discovered compound, has garnered significant attention in the field of biomedicine due to its potential therapeutic applications in diverse disease treatments. Research conducted thus far suggests its efficacy in impeding the proliferation of malignant cells, highlighting its role in the development of targeted cancer therapies. Furthermore, this compound exhibits remarkable antimicrobial properties, rendering it a plausible weapon against bacterial infections. Synonyms: N-1-b-D-Arabinopyranosylamino guanidine HNO3; 368452-60-2; nitric acid; 2-[[(2R,3S,4R,5R)-3,4,5-trihydroxyoxan-2-yl]amino]guanidine; W-202524. CAS No. 368452-60-2. Molecular formula: C6H13N3O4 HNO3. Mole weight: 254.2. | |
| N1-b-D-Galactopyranosylamino-guanidine HCl | N1-b-D-Galactopyranosylamino-guanidine HCl is an esteemed biomedical compound, offering profound utility in the research of diabetes and chronic kidney disease. It demonstrates remarkable prowess as a potent inhibitor that effectively counters the formation of advanced glycation end products. Synonyms: 2-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino]guanidine; hydrochloride; N1-b-D-galactopyranosylamino-guanidine hydrochloride;N1-Beta-d-galactopyranosyl amino-guanidine hydrochloride; N''-[(2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbonohydrazonic diamide--hydrogen chloride (1/1) (non-preferred name); N-{[(2R,3R,4S,5R,6R)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]AMINO}GUANIDINE HYDROCHLORIDE. CAS No. 109853-84-1. Molecular formula: C7H16N4O5 HCl. Mole weight: 272.69. | |
| N1-b-D-Galactopyranosylamino-guanidine HNO3 | N1-b-D-Galactopyranosylamino-guanidine HNO3 is a specialized compound utilized in biomedicine for its potential in treating diabetes. Acting as a potential antiglycation agent, it aims to regulate blood glucose levels by inhibiting the formation of Advanced Glycation End Products (AGEs). Synonyms: N1-B-D-GALACTOPYRANOSYLAMINO-GUANIDINE HNO3; Nitric acid; 2-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino]guanidine; N1-b-D-Galactopyranosylamino-guanidine nitrate salt; W-200809. CAS No. 109853-86-3. Molecular formula: C7H16N4O5 HNO3. Mole weight: 299.24. | |
| N1-b-D-Glucopyranosylamino-guanidine HCl | N1-b-D-Glucopyranosylamino-guanidine HCl is a biomedicine employed in the treatment of diabetes. Acting as an insulin sensitizer, it improves glucose metabolism and enhances insulin sensitivity. This product effectively manages blood sugar levels, specifically targeting hyperglycemia associated with type 2 diabetes. Synonyms: N1-Glycopyranosylamino-guanidines HCl. CAS No. 109853-81-8. Molecular formula: C7H16N4O5 HCl. Mole weight: 272.69. | |
| N1-b-D-Glucopyranosylamino-guanidine HNO3 | N1-b-D-Glucopyranosylamino-guanidine HNO3, a biomedical compound extensively utilized for diabetes treatment, exerts its efficacy as a potent hypoglycemic agent. Its mechanism involves the inhibition of the α-glucosidase enzyme, effectively retarding carbohydrate breakdown and absorption. Remarkably, this compound exhibits promise in regulating postprandial glucose levels and ameliorating insulin resistance among diabetic individuals. Synonyms: N1-b-D-Glucopyranosylamino-guanidine HNO3; 109853-83-0; nitric acid; 2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]amino]guanidine; DTXSID00369548; AKOS025294077; W-200807. CAS No. 109853-83-0. Molecular formula: C7H16N4O5 HNO3. Mole weight: 299.24. | |
| N-(1-Deoxy-D-fructos-1-yl)-L-serine | N-(1-Deoxy-D-fructos-1-yl)-L-serine is a highly potent and meticulously selective pharmaceutical compound, used for studying multifarious afflictions such as diabetes and cancer. Operating through the proficient targeting of precise molecular pathways, this compound actively regulates the intricate intricacies of glucose metabolism. CAS No. 34393-26-5. Molecular formula: C9H17NO8. Mole weight: 267.23. | |
| N-[2-(2-Fluorobenzylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-b-D-glucopyranoside | N-[2-(2-Fluorobenzylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-b-D-glucopyranoside is a biomedical compound utilized for various applications. This product serves as a valuable tool in the investigation of cellular processes and drug development for the research of specific diseases. I. Molecular formula: C34H49FN2O9. Mole weight: 648.76. | |
| N-[2-(2-Hydroxyphenylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside | N-[2-(2-Hydroxyphenylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a pivotal compound extensively employed across the biomedical sector for diverse purposes, aiding in studying select diseases. Molecular formula: C34H50N4O10. Mole weight: 674.78. | |
| N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)triphenylphosphine imide | N-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)triphenylphosphine imide is a chemical compound used in the biomedical industry for research purposes. It has potential applications in the treatment or diagnosis of various diseases such as cancer and diabetes. The compound can also be used as a reagent in chemical synthesis for drug discovery and development. Grades: 98%. CAS No. 6920-4-3. Molecular formula: C32H34NO9P. Mole weight: 607.59. | |
| N-[2-(3-Nitrophenylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside | N-[2-(3-Nitrophenylacetonitrile)]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a biomedical product holding inhibitory effects against specific enzymes involved in the progression of certain ailments such as chronic illnesses. Molecular formula: C34H49N3O11. Mole weight: 675.77. | |
| N-[2-(4-Chlorophenylacetonitrile)]-2,3,4,6-tetra-pivaloyl-D-glucopyranoside | N-[2-(4-Chlorophenylacetonitrile)]-2,3,4,6-tetra-pivaloyl-D-glucopyranoside is a cutting-edge and remarkable compound with remarkable prowess in selectively targeting and obstructing particular enzymes that are intricately involved in the research of manifold diseases such as drug-resistant malignancies and inflammatory ailments. Molecular formula: C34H49ClN2O8. Mole weight: 649.23. | |
| N-[2-(4-Dimethylaminophenyl)-1-cyano-3-butene]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside | N-[2-(4-Dimethylaminophenyl)-1-cyano-3-butene]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside, prevalently employed in the research for various ailments such as cancer and inflammatory disorders. Notably, it serves as an invaluable instrument in the realm of drug design and development, owing to its adeptness in selectively targeting specific cellular pathways. Molecular formula: C39H59N2O9. Mole weight: 699.91. | |
| N-[2-(4'-Dimethylaminophenyl)-1-cyano-3-butene]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside | N-[2-(4'-Dimethylaminophenyl)-1-cyano-3-butene]-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a cutting-edge compound with an extensive range of applications in the domain of inflammatory ailments, particularly focusing on the research of rheumatoid arthritis. It has remarkable inhibitory activity towards vital enzymes implicated in inflammatory pathway. Molecular formula: C39H59N2O9. Mole weight: 699.91. | |
Our database is helping our users find suppliers everyday.
