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Nemolizumab
Nemolizumab is an anti-IL31 receptor A monoclonal antibody that inhibits the IL31 signaling. Nemolizumab has been developed for the treatment of atopic dermatitis. Synonyms: CIM331; CIM 331; CIM-331. CAS No. 1476039-58-3.
N-[(e-N-Benzyloxycarbonylamino)caproyl]-b-D-galactopyranosylamine is an intriguing biomedical compound which can hinder the proliferation of distinct pathogens, thereby used for the research of revolutionary antifungal or antiviral drugs. Molecular formula: C20H31N3O7. Mole weight: 425.48.
NEO 212
NEO 212 is a novel DNA alkylating agent that causes DNA damage and cancer cell apoptosis. It has the potent activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo (IC50 values 5-50 μM for cytotoxicity on glioma cell lines). NEO212 is a conjugate of temozolomide (TMZ) with the natural product perillyl alcohol (POH) and circumvents TMZ-resistance in multiple cancer cell lines and gliomas. Uses: Dna alkylating agent. Synonyms: NEO 212; NEO212; NEO-212; [(4S)-4-Isopropenyl-1-cyclohexen-1-yl]methyl [(3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazin-8-yl)carbonyl]carbamate. Grades: 99%. CAS No. 1361198-79-9. Molecular formula: C17H20N6O4. Mole weight: 372.38.
neo-Inositol
Neo-Inositol, the medicinal supplement renowned for its anti-inflammatory and antioxidant properties in the biomedical industry, is a vital element for metabolic processes and brain function. Neo-Inositol is a key component in treating various maladies, including anxiety, depression, and Alzheimer's. Synonyms: inositol; myo-inositol; Scyllo-inositol; epi-Inositol; Muco-Inositol; Allo-inositol; i-Inositol; 87-89-8; meso-Inositol; Neo-inositol; 643-12-9; D-chiro-Inositol; 1L-Chiro-inositol; D-(+)-chiro-Inositol; cis-Inositol; 488-59-5; 1D-Chiro-inositol; Myoinositol; Scyllitol; 6917-35-7; Cyclohexane-1,2,3,4,5,6-hexaol; 488-58-4; cyclohexane-1,2,3,4,5,6-hexol; Quercinitol; mesoinositol; 551-72-4; Cocositol; Meat sugar; Myoinosite; Dambose; chiro-inositol; Inositene; Inositina; L-chiro-Inositol; Phaseomannite; Inosital; Inosite; Iso-inositol; 41546-34-3; Cyclohexitol; Phaseomannitol. CAS No. 488-54-0. Molecular formula: C6H12O6. Mole weight: 180.16.
Neomangiferin
Mangiferin and neomangiferin inhibited tartrate-resistant acid phosphatase, a biochemical marker of osteoclast function and bone resorption. Uses: Antioxidant. Synonyms: 2-(b-D-Glucopyranosyl)-7-(b-D-glucopyranosyloxy)-1,3,6-trihydroxy-9H-xanthen-9-one. Grades: >98%. CAS No. 64809-67-2. Molecular formula: C25H28O16. Mole weight: 584.48.
Neosamine
Neosamine is a valuable compound used in biomedical field to study various diseases. It exhibits strong antimicrobial properties, making it effective in studying infections caused by bacteria. Molecular formula: C6H14N2O4. Mole weight: 178.19.
Neostibosan
Neostibosan is an arsenic-containing parasitic agent. It has potential activity against tumor cells. Uses: Neostibosan is used as an arsenic-containing parasitic agent. it has potential activity against tumor cells. Synonyms: p-Aminobenzenestibonic acid; Stibanilic acid; Astaril; Bayer-693; Ethylstibamine. Grades: 98%. CAS No. 554-76-7. Molecular formula: C6H8NO3Sb. Mole weight: 263.89.
Used for the isolation of L-fucose binding proteins using affinity chromatography. Uses: Used for the isolation of l-fucose binding proteins using affinity chromatography. Synonyms: [6-[(6-Deoxy-β-L-galactopyranosyl)amino]-6-oxohexyl]carbamic Acid Phenylmethyl Ester. CAS No. 35978-96-2. Molecular formula: C20H30N2O7. Mole weight: 410.46.
Used for the preparation of sugar specific antibodies using liposomes. Uses: Used for the preparation of sugar specific antibodies using liposomes. Synonyms: [6-(β-D-Galactopyranosylamino)-6-oxohexyl]carbamic Acid Phenylmethyl Ester; N-N-Benzyloxycarbonyl-ε-aminocaproyl-β-D-galactopyranosylamine. CAS No. 38822-58-1. Molecular formula: C20H30N2O8. Mole weight: 426.46.
Nesvacumab
Nesvacumab is a human monoclonal antibody targeting Angiopoietin 2. Nesvacumab has the potential for the treatment of various cancers. CAS No. 1296818-77-3.
N-Ethyldeoxynojirimycin HCl
EDNJ HCl is a renowned pharmacological compound in the biomedical industry, used for studying an array of Gaucher disease, Pompe disease and Fabry disease. This compound exhibits immense capabilities as an inhibitor of glucosidases and glycosyltransferases. Synonyms: 1,5-Dideoxy-N-ethyl-1,5-imino-D-glucitol HCl. CAS No. 210241-65-9. Molecular formula: C8H17NO4 HCl. Mole weight: 227.69.
N-Ethyl-D-glucamine
N-Ethyl-D-glucamine (CAS# 14216-22-9) is an ethylated amino sugar derived from Glucose (G595000). It has low vapor pressure and good thermal stability in air, and is used in self-driven microfluidic method to pattern organic films directly in air. Synonyms: (2R,3R,4R,5S)-6-(ethylamino)hexane-1,2,3,4,5-pentol; (2R,3R,4R,5S)-6-(ethylamino)hexane-1,2,3,4,5-pentol. CAS No. 14216-22-9. Molecular formula: C8H19NO5. Mole weight: 209.24.
N-Fmoc-N-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-glucopyranosyl)-L-asparagine is a valuable compound playing a vital role in the synthesis of glycopeptides and glycoproteins. This product finds application in the study of glycosylation processes and the development of potential drugs targeting various diseases, including cancer, bacterial infections and neurodegenerative disorders. Molecular formula: C34H39N3O13. Mole weight: 679.69.
N-Fmoc-O-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl)-L-threonine is an indispensable compound serving as a pivotal component for carbohydrate and glycopeptide synthesis. Its paramount significance lies in the facilitation of drug development, specifically studying afflictions such as cancer, diabetes and infectious diseases. Molecular formula: C33H37NO14. Mole weight: 671.65.
N-Fmoc-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-L-tyrosine is an intriguing compound, tailored for studying diseases related anomalous protein glycosylation, encompassing cancer, diabetes and neurodegenerative disorders. Molecular formula: C39H39NO14. Mole weight: 733.71.
N-Fmoc-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl)-L-thereonine is a potent biomedical compound, used forrevolutionizing the research of cancer, diabetes and infectious diseases alike. Molecular formula: C33H38N2O13. Mole weight: 670.66.
N-Formyl-1-amino-1-deoxy-D-glucitol
N-Formyl-1-amino-1-deoxy-D-glucitol, a compound exhibiting tremendous promise within the biomedical sector, engenders intrigue owing to its distinctive configuration. This extraordinary molecule portrays extraordinary potential in combating an array of ailments, inclusive of diabetes and cancer. Evidential research posits the capability of this compound to judiciously modulate glucose metabolism, facilitating increased insulin receptivity and diminished glycemic indices. Synonyms: 1-Deoxy-1-formamido-D-glucitol; N-(2,3,4,5,6-pentahydroxyhexyl)formamide; 89182-60-5; SCHEMBL12112374. CAS No. 89182-60-5. Molecular formula: C7H15NO6. Mole weight: 209.2.
N-Formyl Varenicline
N-Formyl Varenicline is a metabolite of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: 6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepine-8-carboxaldehyde. CAS No. 796865-82-2. Molecular formula: C14H13N3O. Mole weight: 239.27.
NFPS
NFPS is a non-transportable GlyT1 inhibitor. Synonyms: NFPS; ALX-5407; ALX5407; ALX 5407; N-[3-([1,1-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine. Grades: ≥98% by HPLC. CAS No. 405225-21-0. Molecular formula: C24H24FNO3. Mole weight: 393.45.
N-Glycinyl-1-deoxy-D-glucitol
N-Glycinyl-1-deoxy-D-glucitol is also known as N-GDN, specifically designed for studying diabetes. Its exceptional glucokinase activation properties not only magnify insulin secretion but also augment glucose utilization. Synonyms: N-Glucosylglycine. Molecular formula: C8H17NO7. Mole weight: 239.22.
NH125
NH125 is a potent and selective eEF-2 kinase inhibitor with an IC50 of 60 nM, and also a potent histidine kinase inhibitor. It shows >125-fold selectivity over PKC, PKA, and CaMKII. Synonyms: 3-Benzyl-1-hexadecyl-2-methyl-1H-imidazol-3-ium Iodide; 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-Imidazolium iodide; NSC717205; 1-Benzyl-3-cetyl-2-methylimidazolium iodide; 1H-Imidazolium, 1-hexadecyl-2-methyl-3-(phenylmethyl)-, iodide (1:1). Grades: >98%. CAS No. 278603-08-0. Molecular formula: C27H45IN2. Mole weight: 524.56.
N-(Hydroxyacetyl)-2-O-methyl-a-neuraminic acid
N-(Hydroxyacetyl)-2-O-methyl-a-neuraminic acid is a pivotal compound extensively applied in the biomedical research of an array of afflictions, encompassing viral infections and cancer by impeding the activity of viral neuraminidase and sialyltransferase enzymes. Synonyms: Methyl 3,5-dideoxy-5-glycolamido-a-D-glycero-D-galacto-nonulopyranosidonic acid. CAS No. 14206-42-9. Molecular formula: C12H21NO10. Mole weight: 339.30.
NI 42
NI-42 is a BRPF1 inhibitor with IC50 value of 7.9 nM. Synonyms: NI-42; NI 42; NI42. 4-Cyano-N-(1,2-dihydro-1,3-dimethyl-2-oxo-6-quinolinyl)benzenesulfonamide. Grades: ≥98% by HPLC. CAS No. 1884640-99-6. Molecular formula: C18H15N3O3S. Mole weight: 353.39.
Nicainoprol
Nicainoprol is a sodium channel blocking drug, which is a potent antiarrhythmic agent. Uses: Nicainoprol is an antagonist of calcium channel and a putative class i antiarrhythmic agent. Synonyms: 1,2,3,4-tetrahydro-8-(2-hydroxy-3-(isopropylamino)propoxy)-1-nicotinoylquinoline; RU-42924. Grades: 98%. CAS No. 76252-06-7. Molecular formula: C21H27N3O3. Mole weight: 369.46.
Nicaraven
Nicaraven is a hydroxyl radical scavenger with antivasospastic and neuroprotective effects. Uses: Antioxidants. Synonyms: CP-51974-1 HCl; CP 51974 1 HCl. Grades: >98%. CAS No. 79455-30-4. Molecular formula: C15H16N4O2. Mole weight: 284.31.
Nicotine-N-b-D-glucuronide-D3
Nicotine-N-b-D-glucuronide-D3 is a compound extensively used in research of nicotine metabolism and its association with addiction and related diseases. It is a deuterated form of Nicotine-N-b-D-glucuronide is a major metabolite of nicotine found in urine samples. This labeled compound allows for accurate quantification and analysis in pharmacokinetic studies and elucidation of nicotine's influence on health conditions. Molecular formula: C16H19N2O7D3. Mole weight: 357.37.
Nicotine N-Glucuronide
A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Synonyms: Nicotine N-β-D-Glucuronide; 1-β-D-Glucopyranuronosyl-3-[(2S)-1-methyl-2-pyrrolidinyl]pyridinium Inner Salt; (S)-1-β-D-Glucopyranuronosyl-3-(1-methyl-2-pyrrolidinyl)pyridinium Inner Salt. Grades: > 95%. CAS No. 153536-53-9. Molecular formula: C16H22N2O6 xH2O. Mole weight: 338.36.
Nicotinic acid-acyl-β-D-glucuronide
Nicotinic acid-acyl-β-D-glucuronide is one of Nicotine metabolites, which is a potent parasympathomimetic stimulant. Synonyms: 1-O-(3-Pyridinylcarbonyl)-D-glucopyranuronic acid; D-Glucopyranuronic acid, 1-O-(3-pyridinylcarbonyl)-; β-D-Glucopyranuronic Acid 1-Nicotinate. Grades: 96%. CAS No. 24719-73-1. Molecular formula: C12H13NO8. Mole weight: 299.23.
An organochlorine compound that is urea in which the two hydrogens on one of the amino groups are replaced by nitroso and 2-chloroethyl groups and one hydrogen from the other amino group is replaced by a 4-amino-2-methylpyrimidin-5-ylmethyl] group. An antineoplastic agent especially effective against malignant brain tumors. Uses: Antineoplastic agents. Synonyms: Nimustin; Nimustina; Nimustinum; 1-(4-Amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea; NSC-758675. Grades: >98%. CAS No. 42471-28-3. Molecular formula: C9H13ClN6O2. Mole weight: 272.69.
NIP-301
NIP-301 is a T-type calcium channel blocker potentially used as an analgesic. Uses: Potential analgesic. Synonyms: NIP 301; NIP301.
NIP-302
NIP-302 is a T-type calcium channel blocker potentially used as an analgesic. Uses: Potential analgesic. Synonyms: NIP 302; NIP302.
Nipocalimab
Nipocalimab is a humanized monoclonal antibody targeting the neonatal Fc receptor (FcRn). Nipocalimab has been investigated for the treatment of myasthenia gravis (MG). Synonyms: M281. CAS No. 2211985-36-1.
Nitracrine
Nitracrine, an acridine derivative, inhibits RNA synthesis and is an antitumor drug that has been used clinically for several years. Synonyms: N',N'-dimethyl-N-(1-nitroacridin-9-yl)propane-1,3-diamine; C 283; C-283; C283; Ledakrin; Nitracrine. CAS No. 4533-39-5. Molecular formula: C18H20N4O2. Mole weight: 324.38.
Nitrocaphane
Nitrocaphane is considered as a protocol of choice in the treatment of malignant trophoblastic tumor in combination with 5-FU(fluorouracil). Uses: Nitrocaphane is used in the treatment of malignant trophoblastic tumor in combination with 5-fu(fluorouracil). Synonyms: AT-1258; AT1258; AT 1258; 3-[2-[[Bis(2-chloroethyl)amino]methyl]-5-nitrophenyl]-2-aminopropionic acid; NSC 245413. Grades: 98%. CAS No. 54940-95-3. Molecular formula: C14H19Cl2N3O4. Mole weight: 364.22.
Nitromifene citrate
Nitromifene citrate is a non-steroidal estrogen antagonist. It is structurally similar to Tamoxifen, which is a selective estrogen response modifier. It is most commonly used as a research tool in animal studies. Uses: Nitromifene citrate is most commonly used as a research tool in animal studies. Synonyms: CI-628 citrate; CI 628 citrate; CI628 citrate; 1- (2- (p- (alpha- (p-Methoxyphenyl) -beta-nitrostyryl) phenoxy) ethyl) pyrrolidine citrate (1:1); NSC 110407. Grades: 98%. CAS No. 5863-35-4. Molecular formula: C33H36N2O11. Mole weight: 636.65.
Nivocasan
Nivocasan is a novel caspase-inhibitor has demonstrated hepatoprotective activity in fibrosis/apoptosis animal models. Synonyms: GS 9450; GS9450; GS-9450; LB 84451;LB-84451; LB84451; (R)-N-((2S,3S)-2-(Fluoromethyl)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-5-isopropyl-3-(isoquinolin-1-yl)-4,5-dihydroisoxazole-5-carboxamide. Grades: 98%. CAS No. 908253-63-4. Molecular formula: C21H22FN3O5. Mole weight: 415.42.
NK314
NK314 is a novel synthetic benzo[c]phenanthridine alkaloid that shows strong antitumor activity. It inhibited topoisomerase II activity and stabilized topoisomerase II-DNA cleavable complexes. The DNA breaks occurred within 1h after treatment with NK314 even without digestion of topoisomerase II by proteinase K, whereas etoposide required digestion of the enzyme protein in cleavable complex to detect DNA breaks. Pretreatment with topoisomerase II catalytic inhibitors, ICRF-193 and suramin, reduced both cleavable complex-mediated DNA breaks and proteinase K-independent DNA breaks, but protease inhibitors and nuclease inhibitors only decreased the latter. These results indicate that NK314 might affect topoisomerase II in the different manner from cleavable complex formation and activate intracellular proteinase and nuclease to produce DNA fragmentation. As a result of this unique mechanism of DNA breakage, NK314 showed substantial growth inhibition of topoisomerase II inhibitor-resistant tumors. Synonyms: NK-314; NK 314. Grades: 98%. CAS No. 208237-49-4. Molecular formula: C22H18ClNO4. Mole weight: 395.84.
NLCQ-1
NLCQ-1 is a novel weakly DNA-intercalative bioreductive compound. NLCQ-1 exhibited a C50 of 44 microM. NLCQ-1 demonstrated significant hypoxic selectivity in several rodent (V79, EMT6, SCCVII) or human (A549, OVCAR-3) tumor cell lines. Its potency as a hypoxic cytotoxin ranged between 10 and 136 microM x h, for the cell lines tested, at 30 microM input concentration. NLCQ-1 was a very potent and efficient radiosensitizer of hypoxic V79 cells, providing SER values of 2.27-2.56 at 20-80 microM concentration (measured at 10% survival level). Preclinical results suggest a possible use of NLCQ-1 as adjuvants to radiotherapy. Synonyms: NLCQ 1; NLCQ1; NSC 709257; NSC-709257; NSC709257; 4-(3-(2-nitro-1-imidazolyl)-propylamino)-7-chloroquinoline hydrochloride. CAS No. 221292-08-6. Molecular formula: C15H15Cl2N5O2. Mole weight: 368.22.
[Nle4,D-Phe7]-α-MSH trifluoroacetate salt
[Nle4,D-Phe7]-α-MSH is a synthetic analog of α-melanocyte stimulating hormone (α-MSH). Synonyms: [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt. Grades: ≥95%. Molecular formula: C78H111N21O19·xCF3COOH. Mole weight: 1646.85.
NM-3
NM-3 is an orally bioavailable antiangiogenic isocoumarin with potential antineoplastic activity. NM-3 inhibits vascular endothelial growth factor (VEGF), a pro-angiogenic growth factor, thereby inhibiting endothelial cell proliferation. This agent also induces apoptosis by a mechanism involving reactive oxygen species. Synonyms: NM 3; NM3; isocoumarin NM-3; 2-(8-hydroxy-6-methoxy-1-oxo-1H-isochromen-3-yl)propanoic acid. CAS No. 181427-78-1. Molecular formula: C13H12O6. Mole weight: 264.23.
N-Methyl-b-D-glucopyranosylamine (hydrochloride or other salt)
N-Methyl-b-D-glucopyranosylamine, an esteemed compound found in the biomedical industry, holds great potential in the field of drug development. With its exceptional characteristics, this product lends itself to the treatment of diverse ailments, encompassing diabetes control and cardiovascular disorders. It offers an auspicious avenue for augmenting patient care and overall well-being, showcasing its indispensable role in the therapeutic realm. Synonyms: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(methylamino)oxane-3,4,5-triol; HJFJVGRAUAAGDP-XUUWZHRGSA-N; N-Methyl beta-D-Glucosylamine; SCHEMBL1647661; HJFJVGRAUAAGDP-XUUWZHRGSA-; InChI=1/C7H15NO5/c1-8-7-6(12)5(11)4(10)3(2-9)13-7/h3-12H,2H2,1H3/t3-,4-,5+,6-,7-/m1/s1. CAS No. 114761-39-6. Molecular formula: C7H15NO5 HCl. Mole weight: 229.7.
N-Methyldeoxynojirimycin
N-Methyldeoxynojirimycin is a remarkably efficacious inhibitor applied extensively in the research of hereditary disorders, including Gaucher's disease and Tay-Sachs disease. This phenomenal compound operates by suppressing the enzymatic activity of glucosidase, thereby inducing a noteworthy decline in the concentrations of glucosylceramide and glycolipids. Synonyms: 1,5-Dideoxy-1,5-imino-1-methyl-D-sorbitol; N-Me-DNJ. CAS No. 69567-10-8. Molecular formula: C7H15NO4. Mole weight: 177.2.
N-Methyl-D-glucamine HCI
N-Methyl-D-glucamine HCI is a crucial compound extensively used in the biomedical industry. Its primary application lies in the formulation of contrast agents for diagnostic imaging procedures such as computed tomography (CT) scans. Synonyms: N-Methyl-D-glucamine Hydrochloride; 35564-86-4; N-Methyl-d-glucamine HCl; meglumine hydrochloride; Methylglucamine HCl; Methylglucamine hydrochloride; Methylglucamine chloride; N-Methyl-D-glucamine HCI; Methylglucamine HCl [INCI]; n-methylglucamine hydrochloride; N-Methyl glucamine hydrochloride; D-(-)-N-Methylglucaminium chloride; 2IG86HL9XM; (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hydrochloride; D-Glucitol, 1-deoxy-1-(methylamino)-, hydrochloride; D-Glucitol, 1-deoxy-1-(methylamino)-, hydrochloride (1:1); (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol. CAS No. 35564-86-4. Molecular formula: C7H17NO5 HCl. Mole weight: 231.67.
N-Methyl-D-glucosamine
N-Methyl-D-glucosamine is a crucial compound in the biomedical sector, serving as a precursor molecule in the synthesis of chondroitin sulfate, an indispensable constituent of connective tissues. Synonyms: 2-Deoxy-2-(methylamino)-D-glucose. CAS No. 3329-30-4. Molecular formula: C7H15NO5. Mole weight: 193.20.
N-Methyl-L-glucosamine
N-Methyl-L-Glucosamine, an indispensable constituent of the biomedical realm, exhibits remarkable proficiency. Its principal role lies in serving as a precursor during the synthesis of chitosan, a vital biomaterial. Moreover, it facilitates the therapeutic interventions for diverse afflictions, encompassing osteoarthritis, Alzheimer's disease, and diabetic complications. Synonyms: 2-Deoxy-2-(methylamino)-L-glucose. CAS No. 42852-95-9. Molecular formula: C7H15NO5. Mole weight: 193.20.
N-(n-Butyl)deoxygalactonojirimycin
Lucerastat is a selective α-D-galactosidase inhibitor. It can prevent glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders through inhibiting the ceramide-specific glucosyltransferase, UDP-glucose ceramide glucosyltransferase (IC50 = 41.4 μM) but it does not affect α-glucosidase I and II or β-glucocerebrosidase (IC50s > 1 mM). In Jul 2016, Actelion completed phase Ib trial in Fabry's disease,but no development was reported for the treatment of Lipid metabolism disorders. Uses: Lipid storage disorders and fabry's disease. Synonyms: N-Butyl-1,5-dideoxy-1,5-imino-D-galactitol. Grades: 95%. CAS No. 141206-42-0. Molecular formula: C10H21NO4. Mole weight: 219.28.
N,N-Dimethyl-D-glucosamine
N,N-Dimethyl-D-glucosamine, hailed as a groundbreaking compound, serving as a potent candidate for studying a range of afflictions encompassing osteoarthritis, rheumatoid arthritis and even osteoporosis. Synonyms: 2-Deoxy-2-(dimethylamino)-D-glucose. CAS No. 69947-77-9. Molecular formula: C8H17NO5. Mole weight: 207.22.
N-Nitrosonornicotine-N-b-D-glucuronide - Mixture Of Diastereomers
Cas No. 864071-82-9.
N-n-Octyl-D-glucamine
N-n-Octyl-D-glucamine (CAS# 23323-37-7) is used in the preparation of Dexketoprofen Trometamol. Synonyms: (2R,3R,4R,5S)-6-(octylamino)hexane-1,2,3,4,5-pentol; (2R,3R,4R,5S)-6-(octylamino)hexane-1,2,3,4,5-pentol. CAS No. 23323-37-7. Molecular formula: C14H31NO5. Mole weight: 293.40.
N-Nonyldeoxygalactonojirimycin
N-Nonyldeoxygalactonojirimycin, a remarkable biomedical compound, emerges as a paramount solution in the realm of treating diverse ailments. Renowned for its unrivaled efficacy, it showcases immense potential as a therapeutic agent within enzyme replacement therapies targeting Fabry diseasean intricate lysosomal storage disorder. Synonyms: N-Nonyldeoxygalactonojirimycin; N-(n-Nonyl)deoxygalactonojirimycin; 223771-83-3; (2R,3S,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol; NN-DGJ; SCHEMBL3324203; N-Nonyl-deoxy-galactonojirimycin; W-201929; (2R,3S,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol; (2R,3S,4R,5S)-2-(hydroxymethyl)-1-nonyl-piperidine-3,4,5-triol. CAS No. 223771-83-3. Molecular formula: C15H31NO4. Mole weight: 289.41.
N-Nonyldeoxynojirimycin
N-Nonyldeoxynojirimycin, an efficacious hindrance of glycosidase enzymes, finds practical application in the biomedicine domain to alleviate and mitigate lysosomal storage disorders, namely Gaucher's disease, Fabry disease, and Tay-Sachs disease. Uses: Glycoside hydrolase inhibitors. Synonyms: NN-DNJ. CAS No. 81117-35-3. Molecular formula: C15H31NO4. Mole weight: 289.41.
NNV-009
NNV-009 is an antibody labeled with 177Lu that has the potential use to treat non-Hodgkin's lymphoma and chronic lymphocytic leukemia (CLL). Uses: The potential treatment of non-hodgkin's lymphoma and chronic lymphocytic leukemia (cll). Synonyms: NNV 009; NNV009.
N,O-Didesmethyl venlafaxine D-glucuronide
Nolatrexed
Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity. Uses: Antimetabolites, antineoplastic. Synonyms: 2-amino-6-methyl-5-(pyridin-4-ylthio)quinazolin-4(3H)-one; NSC648316. CAS No. 147149-76-6. Molecular formula: C14H12N4OS. Mole weight: 284.34.
N-omega-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-N-a-Boc-L-asparagine, a compound of utmost importance in the realm of biomedicine, serves as a pivotal asset in managing an array of ailments and afflictions, including cancer, diabetes, and immunological disorders. Synonyms: Nomega-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-N-a-Boc-L-asparagine. CAS No. 137255-40-4. Molecular formula: C17H29N3O10. Mole weight: 435.43.
N-omega-(2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-b-D-glucopyranosyl)-N-alpha-Boc-L-asparagine benzyl ester, an essential compound employed in the biomedical sector, exhibits exceptional attributes that render it indispensable in academic and scientific pursuits. Its utilization spans across diverse disease treatments encompassing cancer and bacterial infections. Functioning as a powerful inhibitory agent, it selectively targets and modulates specific disease-associated pathways and enzymes. Synonyms: Nomega-(2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-beta-D-glucopyranosyl)-Nalpha-(tert-butoxycarbonyl)-L-asparagine Benzyl Ester; N-Omega-(2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-b-D-glucopyranosyl)-N-a-Boc-L-asparagine benzyl ester; benzyl (2S)-4-[[(2R,3R,4R,5S,6R)-3-acetamido-4,5-bis(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]amino]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxobutanoate;Benzyl (2S)-4-({(2R,3R,4R,5S,6R)-3-acetamido-4,5-bis(benzyloxy)-6-[(benzyloxy)methyl]oxan-2-yl}amino)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoate (non-preferred name); N-omega-(2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-beta-D-glucopyranosyl)-N-alpha-Boc-L-asparagine Benzyl Ester; Nomega-(2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-beta-D-glucopyranosyl)-Nalpha-(tert-butoxycarbonyl)-L-asparagineBenzylEster; Nomega-(2-Acetamido-3,4,6-tri-O-benzyl-2-deoxy-beta-D-glucopyranosyl)-Nalpha-Boc-L-asparagine Benzyl Ester. CAS No. 219968-28-2. Molecular formula: C45H53N3O10. Mole weight: 795.92.
Nonanoyl-D-glucopyranoside
Nonanoyl-D-glucopyranoside is a surfactant used in the biomedicine industry for its ability to aid in the solubilization and stabilization of hydrophobic drugs. It has been used in studies to improve the bioavailability of drugs used to treat Alzheimer's disease, as well as enhance the permeability of anti-cancer drugs through cell membranes. Synonyms: Nonanoyl-D-glucopyranoside; 191039-78-8. CAS No. 191039-78-8. Molecular formula: C15H28O7. Mole weight: 320.38.
Norcyclobenzaprine N-glucuronide
Norcyclobenzaprine N-glucuronide is a crucial compound utilized for the investigation and analysis of cyclobenzaprine metabolism. It serves as a biomarker for identifying and quantifying the levels of norcyclobenzaprine N-glucuronide aiding in the assessment and monitoring of drug interactions. Molecular formula: C25H27NO6. Mole weight: 437.49.
Norfluoxetine b-D-glucuronide
Norfluoxetine b-D-glucuronide is a compound used in the research of depression and anxiety disorders. It is a metabolite of the antidepressant drug fluoxetine and it plays a vital role in the pharmacokinetics and elimination of the parent compound. Synonyms: Norfluoxetine N-|A-D-Glucuronide; Norfluoxetine glucuronide; NORFLUOXETINE N-BETA-D-GLUCURONIDE; (2S, 3S, 4S, 5R, 6R) -3, 4, 5-trihydroxy-6-[[3-phenyl-3-[4- (trifluoromethyl) phenoxy]propyl]amino]oxane-2-carboxylic acid; Norfluoxetine N-?-D-Glucuronide;N-{3-Phenyl-3-[4-(trifluoromethyl)phenoxy]propyl}-beta-D-glucopyranuronosylamine; (2S, 3S, 4S, 5R, 6R) -3, 4, 5-trihydroxy-6-[[3-phenyl-3-[4- (triluoromethyl) phenoxy]propyl]amino]oxane-2-carboxylic acid. CAS No. 96735-72-7. Molecular formula: C22H24F3NO7. Mole weight: 471.42.
N-(Phenyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a biomedical product used for studying various diseases. It acts as an inhibitor for specific enzymes involved in the progression of certain cancers. Additionally, it exhibits potential antimicrobial properties against certain bacterial strains. Molecular formula: C35H51NO9. Mole weight: 629.78.
N-(Phenyl-2-methyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a groundbreaking biomedical compound, used for studying formidable inflammatory diseases. Molecular formula: C36H53NO9. Mole weight: 643.81.
N-Propanoyl mannosamine
N-Propanoyl mannosamine is a biomedical compound with inhibitory influence on glycosylation processes allowing for efficacious glycoprotein modification. Synonyms: 2-Deoxy-2-[(1-oxopropyl)amino]-D-mannose. CAS No. 79624-37-6. Molecular formula: C9H17NO6. Mole weight: 235.23.
N-Propionyl-D-glucosamine
N-Propionyl-D-glucosamine, a highly significant biomedical substance, assumes an indispensable role in the treatment of joint-related afflictions while bolstering the well-being of cartilage. Its application conventionally encompasses the formulation of pharmacological agents and remedial approaches to address arthritis, osteoarthritis, and other inflammatory ailments that afflict the joints. Synonyms: N-Propionyl-D-glucosamine; 15475-14-6; N-((3R,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)propionamide; N-[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]propanamide; SCHEMBL15334407; RTEOJYOKWPEKKN-JOHDSVJWSA-N; MFCD00059803; AKOS000369741; AKOS027327732; AS-40587; W-201396. CAS No. 15475-14-6. Molecular formula: C9H17NO6. Mole weight: 235.23.
N-(Propylidenimino)-2-deoxy-3,4,6-tri-O-pivaloyl-D-glucopyranoside is an unprecedented compound utilized in studying diverse bacterial and viral pathologies. Molecular formula: C24H41NO7. Mole weight: 455.58.
NQDI-1
NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell death. Synonyms: NQDI1; NQDI-1; NQDI 1. CAS#175026-96-7. Grades: 98%. CAS No. 175026-96-7. Molecular formula: C19H13NO4. Mole weight: 319.31.
NRX-4204
NRX-4204, also known as NRX-194204 and AGN-194204, is an orally bioavailable synthetic retinoid X receptor (RXR) agonist with potential antineoplastic and anti-inflammatory activities. Rexinoid NRX 194204 selectively binds to and activates RXRs. Because RXRs can form heterodimers with several nuclear receptors (NRs), RXR activation by this agent may result in a broad range of gene expression depending on the effector DNA response elements activated. Rexinoid NRX 194204 may inhibit the tumor-necrosis factor (TNF)-mediated release of nitric oxide (NO) and interleukin 6 (IL6) and may inhibit tumor cell proliferation. This agent appears to be less toxic than RAR-selective ligands. Synonyms: IRX4204; IRX-4204; IRX 4204; NRX4204; NRX-4204; NRX 4204; NRX194204; NRX 194204; NRX-194204; AGN194204; AGN 194204; AGN-194204; VTP 194204; VTP194204; VTP-194204. CAS No. 220619-73-8. Molecular formula: C24H32O2. Mole weight: 352.51.
NS 398
NS 398 is a selective COX-2 inhibitor. Uses: Cyclooxygenase inhibitors. Synonyms: NS-398; NS 398; NS398. N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide. CAS No. 123653-11-2. Molecular formula: C13H18N2O5S. Mole weight: 314.36.
NSC 207895
NSC 207895 suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and also regulates MDM2, an E3 ligase. Synonyms: NSC 207895; NSC-207895; NSC207895; XI-006; XI006; XI 006. Grades: >98%. CAS No. 58131-57-0. Molecular formula: C11H13N5O4. Mole weight: 279.25.