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| Product | Description | |
|---|---|---|
| Crocacin A | It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: (+)-CrocainA; [(2Z,5Z)-6-((6S,7S,8S,9S)-(2E,4E,10E)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenyl-undeca-2,4,10-trienoylamino)-hexa-2,5-dienoylamino]-acetic acid, methyl ester; Methyl 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetate. CAS No. 157698-34-5. Molecular formula: C31H42N2O6. Mole weight: 538.67. |  |
| Crocacin B | It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: [[(2Z,5Z)-6-[[(2E,4E,6S,7S,8R,9S,10E)-7,9-Dimethoxy-3,6,8-trimethyl-1-oxo-11-phenyl-2,4,10-undecatrienyl]amino]-1-oxo-2,5-hexadienyl]amino]acetic acid; 2-[6-((2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienoylamino)(2Z,5Z)hexa-2,5-dienoylamino]acetic acid. CAS No. 237425-37-5. Molecular formula: C30H40N2O6. Mole weight: 524.65. | |
| Crocacin C | It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: (+)-Crocacin C; (2E,4E,10E)(6S,7S,9S,8R)-7,9-Dimethoxy-3,6,8-trimethyl-11-phenylundeca-2,4,10-trienamide; 7,9-dimethoxy-3,6,8-trimethyl-11-phenyl-(2E,4E,6S,7S,8R,9S,10E)-2,4,10-undecatrienamide. CAS No. 237425-38-6. Molecular formula: C22H31NO3. Mole weight: 357.49. | |
| Crocacin D | It is produced by the strain of Chondromyces crocatus sp. Cm c3. It has anti-yeast and filamentous fungal activity. It can inhibit mouse fibroblasts L929 (MIC is 0.2 ng). In the microsomes of the calf's heart, it can interrupt the bc1 segment of electronic transmission, causes redshift of 569nm peak in cytochrome B reduction spectrum. Synonyms: (+)-Crocacin D. CAS No. 237425-39-7. Molecular formula: C31H44N2O6. Mole weight: 540.69. | |
| Crotocin | It is produced by the strain of Cephalosporium crotocinigenum. It has the fungal activity of anti-cryptococcus neoforme, candida albicans, Tinea trichoderma of brewer's yeast, and can be inactivated by blood. Synonyms: Antibiotic T; 4-Isocrotonyloxy-7,8-epoxyscirp-9-ene; Trichothec-9-en-4-beta-ol, 7-beta,8-beta:12,13-diepoxy-, crotonate, (Z)-; Trichothec-9-en-4-ol, 7,8:12,13-diepoxy-, (2Z)-2-butenoate, (4beta,7beta,8beta)-. CAS No. 21284-11-7. Molecular formula: C19H24O5. Mole weight: 332.39. | |
| Cryptochlorophaeic acid | Cryptochlorophaeic acid is obtained from Cladonia cryptochlorophaea Asahina. CAS No. 2948-7-4. Molecular formula: C25H32O8. Mole weight: 460.52. | |
| Cryptophycin 1 | Cryptophycin 1, produced by Nostoc sp. GSV 224, is a potent cytotoxic anti-microtubule agent. Cryptophycin 1 can induce cell apoptosis, and has anti-tumor activity and excellent anti-proliferation ability. Synonyms: Cryptophycin A; Cryptophycin; Cyclo[(2R)-2-methyl-β-alanyl-(2S)-2-hydroxy-4-methylpentanoyl-(2E,5S,6S)-5-hydroxy-6-[(2R,3R)-3-phenyl-2-oxiranyl]-2-heptenoyl-3-chloro-O-methyl-D-tyrosyl]; 1,4-Dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone, 10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-16-[(1S)-1-[(2R,3R)-3-phenyloxiranyl]ethyl]-, (3S,6R,10R,13E,16S)-; (3S,6R,10R,13E,16S)-10-(3-Chloro-4-methoxybenzyl)-3-isobutyl-6-methyl-16-{(1S)-1-[(2R,3R)-3-phenyl-2-oxiranyl]ethyl}-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone. Grade: ≥95%. CAS No. 124689-65-2. Molecular formula: C35H43ClN2O8. Mole weight: 655.19. | |
| Cryptoporic acid A | It is produced by the strain of Cryptoporus volvatus. Synonyms: (2R,3S)-3-Methoxycarbonyl-2-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylene-decahydro-naphthalen-1-ylmethoxy)-pentanedioic acid 1-methyl ester. CAS No. 113592-87-3. Molecular formula: C22H36O7. Mole weight: 412.52. | |
| Cryptoporic acid D | It is produced by the strain of Cryptoporus volvatus. Synonyms: 7,11,24,28-Tetraoxapentacyclo(28.4.0.0(5,34).0(13,18).0(17,22))tetratriacontane-9,26-diacetic acid,8,25-bis(methoxycarbonyl)-13,17,30,34-tetramethyl-4,21-bis(methylene)-10,27-dioxo-,(1R-(1R*,5S*,8R*,9S*,13R*,17S*,18R*,22S*,25R*,26S*,30R*,34S*))-. CAS No. 119979-95-2. Molecular formula: C44H64O14. Mole weight: 816.97. | |
| Cryptoporic acid E | It is produced by the strain of Cryptoporus volvatus. Synonyms: (3S,4R)-3-((((1R,4aS,5S,8aR)-5-((((2R,3S)-3-(carboxymethyl)-1,4-dimethoxy-1,4-dioxobutan-2-yl)oxy)methyl)-1,4a-dimethyl-6-methylenedecahydronaphthalen-1-yl)methoxy)carbonyl)-4-(((1S,4aR,5R,8aS)-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)methoxy)-5-methoxy-5-oxopentanoic acid. CAS No. 120001-10-7. Molecular formula: C45H68O15. Mole weight: 849.01. | |
| Cryptosporiopsin | It is produced by the strain of Cryptosporiopsis sp. and Sporormia affinis. It has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. It also has certain activity against gram-positive bacteria and negative bacteria. Synonyms: (+)-Cryptosporiopsin; 2-Cyclopentene-1-carboxylic acid, 5-dichloro-1-hydroxy-4-oxo-2-propenyl-, methyl ester, (E)-(1S,5S)-(+)-. CAS No. 25707-30-6. Molecular formula: C10H10Cl2O4. Mole weight: 265.09. | |
| Cryptosporiopsin A | It is produced by the strain of Cryptosporiopsis sp. and Sporormia affinis. It has antibacterial activity to many kinds of basidiomycetes, algal fungi, ascomycetes and hemiplegia fungi that cause wood rot, and can inhibit spore germination of Phytophthora potatoes. It also has certain activity to gram-positive bacteria and negative bacteria. Synonyms: (3R,9E)-13-Chloro-4,5,7,8-tetrahydro-14-hydroxy-16-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,6,11(3H,12H)-trione. CAS No. 1402990-52-6. Molecular formula: C19H21ClO6. Mole weight: 380.82. | |
| Cryptosporioptide E | A bioactive polyketide produced by an endophytic fungus Cryptosporiopsis sp. | |
| Cryptothamnolic acid | Cryptothamnolic acid. Synonyms: 3-[(3-Formyl-2-hydroxy-4-methoxy-6-methylbenzoyl)oxy]-4,6-dihydroxy-2,5-dimethylbenzoic acid. CAS No. 258862-16-7. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Cuevaene A | It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. Synonyms: (2E,4Z,6E)-7-(8-hydroxy-1,2,3,4-tetrahydrodibenzo[b,d]furan-1-yl)-4-methoxy-6-methylhepta-2,4,6-trienoic acid. CAS No. 1246172-08-6. Molecular formula: C21H22O5. Mole weight: 354.40. | |
| Cuevaene B | It is produced by the strain of Streptomyces sp. HKI 0180. It has a moderate level of activity against gram-positive bacteria, Its MIC against Staphylococcus aureus and Bacillus subtilis is greater than 50 μg/mL. CAS No. 274684-11-6. Molecular formula: C21H24O7. Mole weight: 388.41. | |
| Culpin | It is produced by the strain of Preussia sp. It has weak antibacterial and antifungal activity. Synonyms: 2-(3-Methyl-2-butenyl)-5-(3-methyl-3-buten-1-ynyl)-1,4-benzenediol. Grade: ≥ 98%. CAS No. 125213-21-0. Molecular formula: C16H18O2. Mole weight: 242.31. | |
| Curromycin A | It is produced by the strain of Streptomyces hygroscipicus 358AV2. It has antibacterial activity against gram-positive bacteria such as Bacillus subtilis. It can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells. Synonyms: Triedimycin A; 4,6,8-Decatrienamide, 3-hydroxy-N-(6-hydroxy-9-(8-hydroxy-1-(methoxymethyl)-5,7-dimethyl-3,6-dioxo-2-oxa-5-azaspiro(3.4)oct-8-yl)-9-methoxy-7-methyl-2,4-nonadienyl-2,2,4-trimethyl-10-(2-methyl-5-oxazolyl)-. CAS No. 97412-76-5. Molecular formula: C38H55N3O10. Mole weight: 713.87. | |
| Curromycin B | It is produced by the strain of Streptomyces hygroscipicus 358AV2. It has antibacterial activity against gram-positive bacteria such as Bacillus subtilis. It can inhibit the replication of human immunodeficiency virus (HIV), inhibit mouse melanoma B16 and leukemia P388 cells. Synonyms: Triedimycin B; 4,6,8-Decatrienamide, 3-hydroxy-N-(6-hydroxy-9-(8-hydroxy-1,5,7-trimethyl-3,6-dioxo-2-oxa-5-azaspiro(3.4)oct-8-yl)-9-methoxy-7-methyl-2,4-nonadienyl-2,2,4-trimethyl-10-(2-methyl-5-oxazolyl)-; 30-Demethoxycurromycin A. CAS No. 97412-77-6. Molecular formula: C37H53N3O9. Mole weight: 683.84. | |
| Curtisian A | It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.15 μg/mL. Synonyms: 3',5',6'-tris(acetyloxy)-4,4''-dihydroxy-1,1':4',1''-terphenyl-2'-yl benzoate; 2',3',6'-Triacetoxy-5'-(benzoyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C31H24O10. Mole weight: 556.52. | |
| Curtisian B | It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.17 μg/mL. Synonyms: 3',5',6'-tris(acetyloxy)-4,4''-dihydroxy-1,1':4',1''-terphenyl-2'-yl 3-phenylpropanoate; 2',3',6'-Triacetoxy-5'-(phenethylcarbonyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C33H28O10. Mole weight: 584.57. | |
| Curtisian C | It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.24 μg/mL. Synonyms: [4-acetyloxy-2,5-bis(3-acetyloxybutanoyloxy)-3,6-bis(4-hydroxyphenyl)phenyl] 3-hydroxybutanoate. Molecular formula: C36H38O15. Mole weight: 710.68. | |
| Curtisian D | It is produced by the strain of Paxillus curtisii. It is a free radical scavenger. It inhibits lipid peroxidation with IC50 of 0.24 μg/mL. Synonyms: 5',6'-bis(acetyloxy)-4,4''-dihydroxy-3'-[(3-phenylpropanoyl)oxy]-1,1':4',1''-terphenyl-2'-yl 3-hydroxybutanoate; 5',6'-Diacetoxy-2'-(3-phenylpropanoyloxy)-3'-(3-hydroxybutanoyloxy)-1,1':4',1''-terbenzene-4,4''-diol. Molecular formula: C35H32O11. Mole weight: 628.62. | |
| Curvularin | It is produced by the strain of Curvularia sp., Penicillum gilmanii and Pen. citroviride. It strongly inhibits cell division and is a toxin harmful to plants. Synonyms: S-Curvularin; NSC 166071; 11,13-Dihydroxy-4-methyl-4,5,6,7,8,9-hexahydro-2H-3-benzoxacyclododecine-2,10(1H)-dione; 2H-3-Benzoxacyclododecin-2,4,5,6,7,8,9-hexahydro-11,13-dihydroxy-4-methyl-, (S)-. Grade: >99% by HPLC. CAS No. 10140-70-2. Molecular formula: C16H20O5. Mole weight: 292.33. | |
| Curvularol | It is produced by the strain of Curvularia sp. RK97-F166. It has weak anti-fungal activity and no anti-bacterial effect. Curvularol of 150 ng/mL inhibits the cell cycle progression of NRK in normal rats at G1 stage. Curvularol of 100 ng/mL can restore the morphology of SRC TS-deformed NRK cells. Like Cycloheximide, it inhibits protein synthesis. Synonyms: (2S,4S,5S,5aR,9aS,10S)-5,5a,8-trimethyl-5a,6,7,9a-tetrahydro-5H-spiro[2,5-methano[1]benzoxepine-4,2'-oxirane]-2,10(3H)-diol. CAS No. 339293-67-3. Molecular formula: C15H22O4. Mole weight: 266.33. | |
| Curvulic acid | It is produced by the strain of Curvularia siddiqui, Penicillum janthynellum C-268. It has weak activity against gram-positive and negative bacteria. Para-aminobenzoic acid can antagonize its action. Synonyms: 2-Acetyl-3,5-dihydroxy-4-methoxy-phenylessigsaeure; 2-Acetyl-3,5-dihydroxy-4-methoxybenzeneacetic acid. CAS No. 652-55-1. Molecular formula: C11H12O6. Mole weight: 240.21. | |
| Curvulinic acid | Curvulinic acid is a phytotoxin isolated from C. siddiqui. Grade: >95% by HPLC. CAS No. 19053-94-2. Molecular formula: C10H10O5. Mole weight: 210.18. | |
| CV-1 | CV-1 is an antibiotic produced by Streptomyces sp. CO-1. It has anti-Escherichia coli activity in combination with spiramycin, and its mechanism is to inhibit lipopolysaccharide synthesis. Synonyms: 1,2-Diamino-1,2-N,N'-carbonyl-1,2-dideoxyglucose hydrate. CAS No. 108351-34-4. Molecular formula: C7H14N2O6. Mole weight: 222.20. | |
| Cyathin A3 | It is produced by the strain of Cyathus helenae, C. africanus. It has weak activity against gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model). CAS No. 38598-35-5. Molecular formula: C20H30O3. Mole weight: 318.45. | |
| Cyathin A4 | It is produced by the strain of Cyathus helenae, C. africanus. It has weak activity against gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model). Molecular formula: C20H30O4. Mole weight: 334.45. | |
| Cyclacidin | It is produced by the strain of Streptomyces capoamus 4670-IA 37. It has anti-individual gram-positive bacteria (subtilis, Gambosia occidentalis) activity, and has inhibitory effect on sarcoma 180 and so on. Synonyms: Bisanhydrorutilantinone; pi-Pyrromycinone; Bisanhydropyrromycinone; eta-Pyrromycinone; 1-Naphthacenecarboxylic acid, 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-, methyl ester; Methyl 6,11-dihydro-6,11-dioxo-2-ethyl-5,7,9-trihydroxy-1-naphthacenecarboxylate; ciclacidine. CAS No. 749-18-8. Molecular formula: C22H16O7. Mole weight: 392.36. | |
| Cyclipostin A | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C23H41O7P. Mole weight: 460.54. | |
| Cyclipostin P | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 30 nmol/L against HSL in rats. Synonyms: (1beta)-4beta-(Hexadecyloxy)-6-methyl-8-oxo-3,5,9-trioxa-4-phosphabicyclo[5.3.0]deca-6-ene 4-oxide; (6S)-6alpha-(Hexadecyloxy)-8-methyl-3,3abeta-dihydro-1H,4H,6H-2,5,7-trioxa-6-phosphaazulene-1-one 6-oxide. Molecular formula: C23H41O6P. Mole weight: 444.54. | |
| Cyclipostin P2 | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 40 nmol/L against HSL in rats. Molecular formula: C23H41O6P. Mole weight: 444.54. | |
| Cyclipostin S | It is produced by the strain of Streptomyces sp. DSM 13381. It is a hormone-sensitive lipase (HSL) inhibitor with a MIC of 20 nmol/L against HSL in rats. Molecular formula: C24H43O6P. Mole weight: 458.57. | |
| Cyclochlorotine | It is produced by the strain of Penicillium islandicum. It can accelerate the degradation of glycogen and make the Liver glycogen particles disappear. Synonyms: Chloropeptide; Cyclic(L-3-phenyl-beta-alanyl-L-seryl-(3S-cis)-3,4-dichloro-L-prolyl-L-alpha-aminobutyryl-L-seryl). Grade: ≥ 98%. CAS No. 12663-46-6. Molecular formula: C24H31Cl2N5O7. Mole weight: 572.44. | |
| Cyclo(delta-Ala-L-Val) | It is a diketopiperazine formed by the fusion of δ-alanine and valine and is a secondary metabolite of fungi and bacteria. It can activate N-acylhomoserine lactones (AHLs) and can also activate or antagonize other LuxR-based quorum-sensing systems. Synonyms: 3-Methylene-6S-(1-methylethyl)-2,5-piperazinedione; 2,5-Piperazinedione, 3-methylene-6-(1-methylethyl)-, (S)-; Cyclo(Δ-Ala-L-Val). Grade: >98% by HPLC. CAS No. 25516-00-1. Molecular formula: C8H12N2O2. Mole weight: 168.19. | |
| Cyclo[D-Leu-L-Pro-] | Cyclo(D-Leu-L-Pro) is a cyclodipeptide found in Phellinus igniarius. It exhibits antitumor and antifungal effects. Synonyms: Cyclo(L-prolyl-D-leucyl); Cyclo(S-Pro-R-Leu); Cyclo-L-prolyl-D-leucine. Grade: 96.0%. CAS No. 36238-67-2. Molecular formula: C11H18N2O2. Mole weight: 210.27. | |
| Cyclo (D-Pro-L-Val) | It is produced by the strain of Aspergillus sp. F70609. It can inhibit β-glucoside enzyme activity with IC50 of 75 μg/mL. It has no or only weak inhibitory effect on other glycosidases. Synonyms: (3S,8aR)-3-isopropylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(1-methylethyl)-, (3S,8aR)-. CAS No. 156617-55-9. Molecular formula: C10H16N2O2. Mole weight: 196.25. | |
| Cycloechinulin | An unusual diketopiperazine isolated from aspergillus ochraceus. It exhibits insecticidal activity against the lepidopteran crop pest, helicoverpa zea. It is used as a secondary metabolite standard for polyphasic taxonomy in aspergillus. Synonyms: (3S)-2,3,8,9-Tetrahydro-11-methoxy-3,8,8-trimethylpyrazino[1',2':1,2]azocino[5,4-b]indole-1,4-dione; (S)-2,3,8,9-Tetrahydro-11-methoxy-3,8,8-trimethyl-pyrazino[1',2':1,2]azocino[5,4-b]indole-1,4-dione. Grade: >99% by HPLC. CAS No. 143086-29-7. Molecular formula: C20H21N3O3. Mole weight: 351.40. | |
| Cycloepoxydon | It is produced by the strain of Duteromycete 45-93. It can inhibit TPA induced expression of k gene binding nuclear factor (NF-KB) and activator protein-1 (APT-1) mediated secreted alkaline phosphatase (SEAP), with IC50 of 4.2-9.4 mol/L and 4.2-9.4 mol/L, respectively. Molecular formula: C12H16O5. Mole weight: 240.25. | |
| Cyclogregatin | It is produced by the strain of Aspergillus panamensis. It has anti-bacterial and fungal activity, but its antibacterial and fungal activity is lower than polymyxin A. It inhibits airy ascites carcinoma with MIC of 10 μg/mL (Gregatin A is 2 μg/mL). Synonyms: 4H-Furo(2,3-b)pyran-3,4(2H)-dione, 2-(1,3-hexadienyl)-5,6-dihydro-2,6-dimethyl-. CAS No. 120167-25-1. Molecular formula: C15H18O4. Mole weight: 262.30. | |
| Cycloheptamycin | It is produced by the strain of Streptomyces sp. MZ 1158. It has anti-gram-positive bacterial and mycobacterium activity. CAS No. 30270-78-1. Molecular formula: C48H68N8O12. Mole weight: 949.10. | |
| cyclo(L-Ala-L-Leu) | Cyclo(L-Ala-L-Leu) is a cyclic diketopiperazine found in fungi and bacteria. It has antiviral activity. Grade: >95% by HPLC. CAS No. 24676-83-3. Molecular formula: C9H16N2O2. Mole weight: 184.24. | |
| Cycloleucomelone | It is produced by the strain of Boletopsis leucomelaena. Synonyms: Cycloleucomelon; 2,7,8-Trihydroxy-3-(4-hydroxy-phenyl)-dibenzofuran-1,4-dione. CAS No. 112209-48-0. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Cyclo(L-Leu-L-Trp) | Cyclo(L-Leu-L-Trp) is a diketopiperazine metabolite originally isolated from Penicillium. It is active against various bacteria and fungi, and it also inhibits the production rate of hydroxy radicals in an electron spin resonance (ESR) spectroscopy-based assay (IC50 = 1.8 μM). Synonyms: 3S-(1H-indol-3-ylmethyl)-6S-(2-methylpropyl)-2,5-piperazinedione; Cyclo(L-leucyl-L-tryptophyl); Cyclo(leu-trp); Cyclo(L-Trp-L-Leu); 2,5-Piperazinedione, 3-(1H-indol-3-ylmethyl)-6-(2-methylpropyl)-, (3S-cis)-. Grade: ≥95%. CAS No. 15136-34-2. Molecular formula: C17H21N3O2. Mole weight: 299.37. | |
| Cyclo(L-Leu-trans-4-hydroxy-L-Pro) | Cyclo(L-Leu-trans-4-hydroxy-L-Pro) is a natural compound isolated from Phellinus igniarius. It is a plant growth regulator. Synonyms: Cyclo(L-leucyl-trans-4-hydroxy-L-proline); Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-3-(2-methylpropyl)-, (3S,7R,8aS)-; L-hydroxyprolyl-L-leucine anhydride; cyclo[L-(4-hydroxyprolinyl)-L-leucine]; 7-Hydroxygancidin W. Grade: ≥95%. CAS No. 115006-86-5. Molecular formula: C11H18N2O3. Mole weight: 226.27. | |
| Cyclo(L-phenylalanyl-trans-4-hydroxy-L-proline) | Cyclo(L-Phe-trans-4-hydroxy-L-Pro) is a cyclodipeptide from the fermentation broth of Streptomyces sp. YIM67005. It is a plant growth regulator. Synonyms: L-Phe-trans-4-hydroxy-L-Pro; (4R)-4-Hydroxycyclo(L-Pro-L-Phe-); Cyclo-(L-phenylalanyl-4R-hydroxy-L-proline); Cyclo[(4-hydroxyprolinyl)-L-phenylalanine]; cyclo-(L-phenylalanine-trans-4-hydroxy-L-proline). Grade: 95%. CAS No. 118477-06-8. Molecular formula: C14H16N2O3. Mole weight: 260.29. | |
| cyclo(L-Tyr-L-Val) | Cyclo(L-Tyr-L-Val) is a diketopiperazine metabolite isolated from marine actinomycetes (Nocardiopsis gilva). Synonyms: Cyclo(Tyr-Val). Grade: >95% by HPLC. CAS No. 21754-25-6. Molecular formula: C14H18N2O3. Mole weight: 262.3. | |
| Cyclononylprodiginine | Cyclononylprodiginine is a prodigiosin antibiotic. CAS No. 34852-35-2. Molecular formula: C23H29N3O. Mole weight: 363.49. | |
| Cyclooctatin | It is produced by the strain of Sreptomyces melanosporofaciens M1614-43F2. It can inhibit the hemolysis phospholipase [EC 3.1.1.5] (Lyso-PL) activity. Terpentecin as substrates, it inhibits Lyso-PL, PL-A2, PL-C and PL-D with IC50 of 2.9 μg/mL, 65.0 μg/mL, 70.0 μg/mL and >100 μg/mL, respectively. Ki is 4.8 X 10-6 mol/L. Synonyms: Dicyclopenta(a,d)cyclooctene-3,4-diol,1,2,3,3a,4,5,7,8,9,9a,10,10a-dodecahydro-4,9a-dimethyl-1-(hydroxymethyl)-7-(1-methylethyl)-; 1-(Hydroxymethyl)-7-isopropyl-4,9a-dimethyl-1,2,3,3a,4,5,7,8,9,9a,10,10a-dodecahydrodicyclopenta[a,d]cyclooctene-3,4-diol. CAS No. 139552-97-9. Molecular formula: C20H34O3. Mole weight: 322.49. | |
| Cyclopaldic acid | It is produced by the strain of Penicillum cyclopium var. album, Pen. cyclopium 77. Cyclopaldic acid of 2.5 μg/mL can inhibit the spore germination of Garlic botrytis spore 95%-100%. Synonyms: 3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-1,3-dihydro-2-benzofuran-4-carbaldehyde; 1,3-Dihydro-3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-4-isobenzofurancarboxaldehyde; Cyclopaldsaeure. CAS No. 477-99-6. Molecular formula: C11H10O6. Mole weight: 238.19. | |
| (±)-Cyclopenin | (±)-Cyclopenin is produced by a benzodiazepine metabolite produced by Penicillium. It is almost non-toxic to mammalian cells, bacteria or fungi in vitro. Synonyms: Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'R)-rel-. Grade: >99% by HPLC. CAS No. 19553-26-5. Molecular formula: C17H14N2O3. Mole weight: 294.30. | |
| Cyclopentanone, 2-(5-bromo-2-methoxy-4-methylphenyl)-2-methyl- | Cyclopentanone, 2-(5-bromo-2-methoxy-4-methylphenyl)-2-methyl-. Synonyms: 2-(5-Bromo-2-methoxy-4-methylphenyl)-2-methylcyclopentanone. CAS No. 23963-91-9. Molecular formula: C14H17BrO2. Mole weight: 297.19. | |
| Cyclopeptine | A benzodiazepine metabolite produced by a number of species of penicillium. Synonyms: (S)-cyclopeptine; (3S)-3-benzyl-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione. Grade: >99% by HPLC. CAS No. 50886-63-0. Molecular formula: C17H16N2O2. Mole weight: 280.32. | |
| Cyclophellitol | Cyclophellitol, originally isolated from a species of Phellinus mushroom, is a potent and irreversible beta-glucosidase inhibitor. Synonyms: (1R,2S)-1β,2β-Epoxy-6β-hydroxymethylcyclohexane-3α,4β,5α-triol; D-Myo-inositol, 1,2-anhydro-3-deoxy-3-(hydroxymethyl)-; (+)-Cyclophellitol; epi-CPL; 1,6-epi-Cyclophellitol; 7-Oxabicyclo[4.1.0]heptane-2,3,4-triol, 5-(hydroxymethyl)-, (1S,2R,3S,4R,5R,6R)-; 1,2-Anhydro-3-deoxy-3-(hydroxymethyl)-D-myo-inositol. Grade: ≥95%. CAS No. 126661-83-4. Molecular formula: C7H12O5. Mole weight: 176.17. | |
| Cyclophostin | It is produced by the strain of Streptomyces lavendulae NK901093. It strongly inhibits AChE activity, it inhibits the AchE of houseflies with IC50 of 7.6 X 10-10 mol/L. Synonyms: Rac-Cyclophostin; 1H,6H-Furo(3,4-e)(1,3,2)dioxaphosphepin-6-one,8,8a-dihydro-3-methoxy-5-methyl-, 3-oxide, (3R-cis)-. CAS No. 144773-26-2. Molecular formula: C8H11O6P. Mole weight: 234.14. | |
| Cyclosporine Impurity 3 Sodium Salt | Cyclosporine Impurity 3 Sodium Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Grade: ≥90% by HPLC. Molecular formula: C7H14NO3Na. Mole weight: 183.18. | |
| Cyclothialidine | It is produced by the strain of Streptomyces filipinensis NR 0484. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.3 μmol/L, and the reference neomycin was 1.2 μmol/L. Synonyms: Cyclothialidine A; (2S)-2-[[(5S,8R)-5-[[(2S,3R)-1-(2-amino-3-hydroxypropanoyl)-3-hydroxypyrrolidine-2-carbonyl]amino]-13,15-dihydroxy-16-methyl-2,6-dioxo3-oxa-10-thia-7-azabicyclo[10.4.0]hexadeca-1(16),12,14-triene-8-carbonyl]amino]propanoic acid; N-[[(4R,7S)-1,3,4,5,6,7,8,10-octahydro-12,14-dihydroxy-7-[[(3R)-3-hydroxy-1-L-seryl-L-prolyl]amino]-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecin-4-yl]carbonyl]-L-alanine. CAS No. 147214-63-9. Molecular formula: C26H35N5O12S. Mole weight: 641.65. | |
| Cyclothialidine B | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-76-1. Molecular formula: C25H33N5O11S. Mole weight: 611.62. | |
| Cyclothialidine C | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 161161-54-2. Molecular formula: C26H35N5O11S. Mole weight: 625.66. | |
| Cyclothialidine D | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-78-3. Molecular formula: C24H31N5O11S. Mole weight: 597.60. | |
| Cyclothialidine E | It is produced by the strain of Streptomyces sp. NR 0659. It and its homologues inhibit escherichia coli DNA helicases with IC50 of 0.7 μmol/L, and the reference neomycin was 1.2 μmol/L. CAS No. 194276-79-4. Molecular formula: C25H33N5O11S. Mole weight: 611.63. | |
| Cyclothiazomycin | It is produced by the strain of Streptomyces sp. NR0516. It selectively inhibits renin activity and does not inhibit pepsin, aspartic acid, serine, mercaptan protease and metalloproteinases. In addition, it has weak antifungal activity. Synonyms: cyclothiazomycin A; 5102-II. CAS No. 133352-26-8. Molecular formula: C59H64N18O14S7. Mole weight: 1473.71. | |
| Cyclothiocurvularin A | Cycuriocurvularin is a 12-membered macrolide isolated from Penicillium and Curvularia sp. Grade: >95% by HPLC. Molecular formula: C19H22O8S. Mole weight: 410.44. | |
| Cycloviracin B1 | Cycloviracin B1 is produced by the strain of Kibdelosporangium albatum sp. R761-7. It has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-gram-positive bacterial activity. Synonyms: (1S,3R,8R,9S,10S,11S,12R,14R,19S,20S,21R,22S)-3-((16R)-16,22-bis(((2S,3R,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)oxy)tricosyl)-14-(14-(((2S,3R,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)oxy)-20-hydroxyhenicosyl)-9,10,11,20,21,22-hexahydroxy-2,6,13,17,23,24-hexaoxatricyclo[17.3.1.18,12]tetracosane-5,16-dione. CAS No. 142382-45-4. Molecular formula: C83H152O33. Mole weight: 1678.07. | |
| Cycloviracin B2 | Cycloviracin B2 is produced by the strain of Kibdelosporangium albatum sp. R761-7. It has anti-herpes simplex virus Type I (HSV-1) activity and has weak anti-gram-positive bacterial activity. CAS No. 142382-46-5. Molecular formula: C83H150O33. Mole weight: 1676.06. | |
| CYL-2 | CYL-2 is a cyclic tetrapeptide produced by the strain of Cylindrocladium scoparium. It has anti-bacterial activity. Synonyms: (3s,6r,15as)-9-[(2s)-butan-2-yl]-6-(4-methoxybenzyl)-3-[6-(oxiran-2-yl)-6-oxohexyl]octahydro-2h-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3h,12h)-tetrone; Cyclo(O-methyltyrosine-L-isoleucine-L-pipecolic acid-2-amino-8-oxo-9,10-epoxydecanoic acid). CAS No. 42002-26-6. Molecular formula: C32H46N4O7. Mole weight: 598.73. | |
| Cymbimicin A | It is produced by the strain of Micromonospora sp. A92-313709. Cymbimicin A had a strong affinity with cyclosporin-binding protein, and the affinity between Cymbimicin B and cyclosporin-binding protein was about 100 times lower than that of Cymbimicin A. CAS No. 200563-97-9. Molecular formula: C59H92N4O14. Mole weight: 1053.36. | |
| Cymbimicin B | It is produced by the strain of Micromonospora sp. A92-313709. Cymbimicin B had a strong affinity with cyclosporin-binding protein, and the affinity between Cymbimicin B and cyclosporin-binding protein was about 100 times lower than that of Cymbimicin A. CAS No. 200564-07-4. Molecular formula: C58H86N2O13. Mole weight: 1019.31. | |
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