BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Cyrmenin A | It is produced by the strain of Cystobacter armeniaca Cb a24, Archangium gephyra Ar 9944. It is a β-methoxy acrylic acid (MOA) inhibitor. Cyrmenin A inhibits NADH oxidation of bovine heart submitochondrial particles with IC50 of 27 ng/mL. The mechanism is to block the bc1 phase of electron transport in the respiratory chain. CAS No. 675150-03-5. Molecular formula: C22H34N2O5. Mole weight: 406.51. |  |
| Cyrmenin B1 | It is produced by the strain of Cystobacter armeniaca Cb a24, Archangium gephyra Ar 9944. It is a β-methoxy acrylic acid (MOA) inhibitor. Cyrmenin B1 inhibits NADH oxidation of bovine heart submitochondrial particles with IC50 of 41 ng/mL. The mechanism is to block the bc1 phase of electron transport in the respiratory chain. CAS No. 675150-04-6. Molecular formula: C21H32N2O5. Mole weight: 392.49. | |
| Cyrmenin B2 | It is produced by the strain of Cystobacter armeniaca Cb a24, Archangium gephyra Ar 9944. It is a β-methoxy acrylic acid (MOA) inhibitor. Cyrmenin B2 inhibits NADH oxidation of bovine heart submitochondrial particles with IC50 of 159 ng/mL. The mechanism is to block the bc1 phase of electron transport in the respiratory chain. CAS No. 672929-30-5. Molecular formula: C21H32N2O5. Mole weight: 392.49. | |
| Cystothiazole A | It is produced by the strain of Cystobacter fuscus. It has antifungal activity. It can inhibit candida albicans, saccharomyces cerevisiae and aspergillus smoke with MIC of 0.4 μg/mL, 0.1 μg/mL and 1.6 μg/mL, respectively. It also inhibits human tumor cell, such as HPT-116 and K562 cells with MIC of 130 ng/mL and 110 ng/mL, respectively. It has no anti-bacterial effect. Synonyms: Melithiazole E; (+)-cystothiazole A; methyl (2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-[2'-(propan-2-yl)-2,4'-bi-1,3-thiazol-4-yl]hepta-2,6-dienoate; (2E,6E)-(4R,5S)-7-(2'-Isopropyl-[2,4']bithiazolyl-4-yl)-3,5-dimethoxy-4-methyl-hepta-2,6-dienoic acid methyl ester. CAS No. 207399-36-8. Molecular formula: C20H26N2O4S2. Mole weight: 422.56. | |
| Cystothiazole B | It is produced by the strain of Cystobacter fuscus. It has no anti-bacterial effect. CAS No. 207399-38-0. Molecular formula: C20H26N2O5S2. Mole weight: 438.56. | |
| Cytochalasin A | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytochalasin A is an HIV protease inhibitor. Synonyms: NSC174119; Dehydrophomin; 5-Dehydrophomin; 5,5-Didehydrophomin; 2H-Oxacyclotetradecino(2,3-d)isoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E,9R,11E,12aS,13S,15S,15aS,16S,18aS)-; (7S,13E,16R,21E)-7-Hydroxy-16-methyl-10-phenyl-24-Oxa[14]cytochalasa-6(12),13,21-triene-1,20,23-trione; 16-Benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-2H-Oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione. Grade: >98% by HPLC. CAS No. 14110-64-6. Molecular formula: C29H35NO5. Mole weight: 477.59. | |
| Cytochalasin B | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine B has immunosuppressive effects. Synonyms: (7S,13E,16R,20R,21E)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione; (E,E)-(5R,9R,12aS,13S,15S,15aS,16S,18aS)-16-Benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione; NSC 107658; Phomin. Grade: >99% by HPLC. CAS No. 14930-96-2. Molecular formula: C29H37NO5. Mole weight: 479.61. | |
| CYTOCHALASIN D | It is produced by the strain of Metarrhizium anisopliae, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Uses: Anti-hypertensive. Synonyms: (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1,11(2H)-dione; (7S,13E,16S,18R,19E,21R)-[11]21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenylcytochalasa-6(12),13,19-triene-1,17-dione; (-)-Cytochalasin D; 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-; NSC 209835; Zygosporin A; Cytohalasin D; Lygosporin A. Grade: >98%. CAS No. 22144-77-0. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
| Cytochalasin E | It is produced by the strain of Rosellina necatrix. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: (7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione; NSC 175151; [4S-(1E,4R*,6S*,7E,11aR*,14R*,14aR*,15R*,15aS*,16aR*,16bR*)]-3,13,14,14a,15,15a,16a,16b-Octahydro-6-hydroxy-4,6,15,15a-tetramethyl-14-(phenylmethyl)-[1,3]Dioxacyclotridecino[4,5-d]oxireno[f]isoindole-5,10,12(4H,6H)-trione. Grade: >99% by HPLC. CAS No. 36011-19-5. Molecular formula: C28H33NO7. Mole weight: 495.56. | |
| Cytochalasin F | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: (7S,13E,16R,20R,21E)-6,7-Epoxy-20-hydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-13,21-diene-1,23-dione; 24-Oxa(14)cytochalasa-13,21-diene-1,23-dione,6,7-epoxy-20-hydroxy-16-methyl-10-phenyl-, (7S,13E,16R,20R,21E)-. CAS No. 36084-18-1. Molecular formula: C29H37NO5. Mole weight: 479.61. | |
| Cytochalasin G | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. CAS No. 54874-57-6. Molecular formula: C29H34N2O4. Mole weight: 474.59. | |
| Cytochalasin H | It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine H has immunosuppressive effects. Synonyms: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-[11]Cytochalasa-6(12),13,19-trien-1-one; (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-15-(Acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; Cytochalasin H; Kodocytochalasin 1; Paspalin P I; [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-15-(Acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; Paspalin; SC 305222; NSC305222; NSC-305222; (11)Cytochalasa-6(12),13,19-trien-1-one; phenyl-(11)cytochalasa-6(12),13,19-triene-1-one. Grade: >95% by HPLC. CAS No. 53760-19-3. Molecular formula: C30H39NO5. Mole weight: 493.63. | |
| Cytochalasin J | It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine J has immunosuppressive effects. Synonyms: Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II; [3S-(3R*,3aS*,4R*,6R*,6aS*,7E,10R*,12S*,13E,15S*,15aS*)]-2,3,3a,4,5,6,6a,9,10,11,12,15-Dodecahydro-6,12,15-trihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; (7S,13E,16S,18R,19E,21R)-7,18,21-Trihydroxy-16,18-dimethyl-10-phenyl-[[11]cytochalasa-6(12),13,19-trien-1-one. Grade: ≥ 95%. CAS No. 56144-22-0. Molecular formula: C28H37NO4. Mole weight: 451.60. | |
| Cytochalasin K | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 3H-Cyclotridec(d)oxireno(f)isoindole-8,11,12(13H)-trione, 7-(acetyloxy)-4,7,14,14a,15,15a,16a,16b-octahydro-4,6,15,15a-tetramethyl-14-(phenylmethyl)-, (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,15aR,16aS,16bR)-. CAS No. 79648-72-9. Molecular formula: C32H37NO6. Mole weight: 531.64. | |
| Cytochalasin L | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 24-Oxa(14)cytochalasa-13,17,21-triene-1,20,23-trione, 19-(acetyloxy)-6,7-epoxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,17E,19R,21E)-; 3H-Oxacyclotetradecino(2,3-d)oxireno(f)isoindole-8,11,13(14H)-trione, 7-(acetyloxy)-4,7,15,15a,16,16a,17a,17b-octahydro-4,6,16,16a-tetramethyl-15-(phenylmethyl)-, (1E,4S,5E,7R,9E,12aS,15S,15aS,16S,16aR,17aS,17bS)-. CAS No. 79637-87-9. Molecular formula: C32H37NO7. Mole weight: 547.64. | |
| Cytochalasin M | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 24-Oxa(14)cytochalasa-13,17-diene-1,19,23-trione, 6,7-epoxy-20-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,17E,20S)-; 3H-Oxacyclotetradecino(2,3-d)oxireno(f)isoindole-7,11,13(4H,8H,14H)-trione,9,10,15,15a,16,16a,17a,17b-octahydro-8-hydroxy-4,6,16,16a-tetramethyl-15-(phenylmethyl)-, (4S-(1E,4R*,5E,8R*,12ar*,15R*,15ar*,16R*,16as*,17ar*,17br*))-. CAS No. 79648-73-0. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
| Cytogenin | It is produced by the strain of Streptoverticillium eurocidicum. It has weak cytotoxicity. Synonyms: Antibiotic MI 43-37F 11; 8-Hydroxy-3-(hydroxymethyl)-6-methoxy-1H-2-benzopyran-1-one; 1H-2-Benzopyran-1-one,8-hydroxy-3-(hydroxymethyl)-6-methoxy-. CAS No. 132971-59-6. Molecular formula: C11H10O5. Mole weight: 222.19. | |
| Cytorhodin A | It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It can inhibit the growth of P388 murine lymphocytic leukemia cells with IC50 of 2.9 ng/mL. Synonyms: 1-Deoxyobelmycin B; A-447C; Antibiotic A-447C; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-, (7R,8R,10S)-; [7R-(7a,8b,10b)]-8-Ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[[2S-[2a,5b(2R*,5R*,6R*),6b]]-tetrahydro-6-methyl-5-[(tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione. CAS No. 95599-38-5. Molecular formula: C60H88N2O20. Mole weight: 1157.34. | |
| Cytorhodin X | It is produced by the strain of Streptomyces sp. HPLY-11472 (DSM 2658). It belongs to Rhodimycin group antibiotic. The ED50 of L1210 cell is 0.36 μmol/L (The ED50 of adriamycin in the control group is 0.036 μmol/L). Synonyms: Cytorhodin A, 7-de((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2-alpha,5-beta(2R*,5R*,6R*),6-beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-9-O-(2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)-. CAS No. 133914-58-6. Molecular formula: C48H68N2O15. Mole weight: 913.06. | |
| Cytosaminomycin A | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin A without cleavage in chicken embryo cells is 0.3-0.6 μg/mL. Synonyms: N-[3-(Methylthio)acryloyl]-1-[4-O-[4-(dimethylamino)-4,6-dideoxy-alpha-D-glucopyranosyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]cytosine. CAS No. 157878-02-9. Molecular formula: C22H34N4O8S. Mole weight: 514.59. | |
| Cytosaminomycin B | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin B without cleavage in chicken embryo cells is 0.3-0.6 μg/mL. Synonyms: 2(1H)-pyrimidinone, 1-[2,6-dideoxy-4-o-[4,6-dideoxy-4-(dimethylamino)-alpha-D-glucopyranosyl]-beta-L-arabino-hexopyranosyl]-4-[[4-(methylamino)benzoyl]amino]-. CAS No. 157878-03-0. Molecular formula: C26H37N5O8. Mole weight: 547.60. | |
| Cytosaminomycin C | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin C without cleavage in chicken embryo cells is 0.3-0.6 μg/mL. CAS No. 157878-04-1. Molecular formula: C23H36N4O8. Mole weight: 496.55. | |
| Cytosaminomycin D | It is produced by the strain of Streptomyces sp. KO-8119. It has anti-eimeria Tenella activity. The concentration of Cytosaminomycin D without cleavage in chicken embryo cells is 2.5 μg/mL. Synonyms: N-(2-Methyl-2-butenoyl)-1-[4-O-[4-(dimethylamino)-4,6-dideoxy-alpha-D-glucopyranosyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]cytosine. CAS No. 157878-05-2. Molecular formula: C23H36N4O8. Mole weight: 496.55. | |
| Cytosporin A | Cytosporin A is an angiotensin II receptor antagonist produced by Cytospora sp. Cytosporin A selectively inhibits the binding of angiotensin II to the AT2 site of the receptor with IC50 of 1.5-3.0 mol/L (0.5 to 1 μg/mL). Molecular formula: C17H24O5. Mole weight: 308.37. | |
| Cytosporin B | Cytosporin B is a minor component produced by Cytospora sp. Molecular formula: C17H27ClO5. Mole weight: 346.85. | |
| Cytosporin C | Cytosporin C is a minor component produced by Cytospora sp. Molecular formula: C17H26O5. Mole weight: 310.38. | |
| Cytovaricin | Cytovaricin is an antibiotic produced by Streptomyces sp. H-230 and Str. collinus H-230. It has the activity of inhibiting Yoshida sarcoma cells and has weak anti-phytopathogenic fungi and chlorella activity. CAS No. 79553-45-0. Molecular formula: C47H80O16. Mole weight: 901.13. | |
| Cytovaricin B | Cytovaricin B is a Janus kinase-signal transducer and activation protein (JAK-STAT) inhibitor produced by Streptamyces torulosus 3197-GM1. CAS No. 129985-88-2. Molecular formula: C48H82O16. Mole weight: 915.15. | |
| Cytoxazone | Cytoxazone is a cytokine regulator produced by Streptornyces sp. RK95-31. It inhibits the production of IL-4 and IL-10 induced by Pokeween mitogen (PWM) at 6.25-25 μg/mL, but does not inhibit the production of GM-CSF induced by PWM. Synonyms: (-)-Cytoxazone. Grade: >98%. CAS No. 42902-32-9. Molecular formula: C11H13NO4. Mole weight: 223.22. | |
| D2-eprinomectin B1a | D2-eprinomectin B1a. | |
| D788-1 | D788-1 is produced by the strain of Streptomyces sp. D788. It had inhibitory activity against L1210 with IC50 of 0.027 μg/mL. Synonyms: 10-Carboxy-13-deoxycarminomycin; D-788-1; Carbolbicin; 4-[(3-Amino-2,3,6-trideoxyhexopyranosyl)oxy]-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylic acid. CAS No. 97583-07-8. Molecular formula: C27H29NO11. Mole weight: 543.52. | |
| Dactimicin | Dactimicin is an aminoglycoside antibiotic produced by Dactilosporangium matsuzakiense SF-2O52. It has anti-gram-positive and negative bacteria activity. Synonyms: SF-2052. Grade: >98%. CAS No. 73196-97-1. Molecular formula: C18H36N6O6. Mole weight: 432.51. | |
| Dactimicin sulfate | Dactimicin sulfate is an aminoglycoside antibiotic produced by Dactilosporangium matsuzakiense SF-2O52. It has anti-gram-positive and negative bacteria activity. Synonyms: Antibiotic SF 2052 sulfate; L-chiro-Inositol, 4-amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(2-(formimidoylamino)-N-methylacetamido)-, sulfate (1:2), hydrate. Grade: >98%. CAS No. 73245-91-7. Molecular formula: C18H40N6O14S2. Mole weight: 628.67. | |
| Dactylarin | Dactylarin is an antibiotic produced by Dactylaria lutea. It has strong anti-Leishmania and Enterobacter activity, anti-Gram-positive bacteria activity, but no anti-negative bacteria, yeast and mold activity. Synonyms: Altersolanol B. Grade: >98%. CAS No. 22350-90-9. Molecular formula: C16H16O6. Mole weight: 304.29. | |
| Dactylfungin A | Dactylfungin is an antifungal antibiotic produced by Dactylaria parvispora D500 and separates the two components A and B. A and B have no antibacterial activity. Synonyms: 2H-Pyran-2-one, 3-(4-deoxy-beta-xylo-hexopyranosyl)-4-hydroxy-6-(2-hydroxy-7-(hydroxymethyl)-1,1,5,9,11,13,17,19-octamethyl-3,5,13,15,17-heneicosapentaenyl)-. CAS No. 146935-35-5. Molecular formula: C41H64O9. Mole weight: 700.94. | |
| Dactylfungin B | Dactylfungin is an antifungal antibiotic produced by Dactylaria parvispora D500, and two components A and B are separated. A and B have no antibacterial activity. B is resistant to individual Candida and Saccharomyces fungi (MIC 3.1-6.2 μg/mL), and has a weak effect on important pathogenic fungi such as Candida albicans (MIC >100μg/mL). Synonyms: 4H-Pyran-4-one, 3-(4-deoxy-beta-xylo-hexopyranosyl)-2-hydroxy-6-(2-hydroxy-7-(hydroxymethyl)-1,1,5,9,11,13,17,19-octamethyl-3,5,13,15,17-heneicosapentaenyl)-. CAS No. 146935-36-6. Molecular formula: C41H64O9. Mole weight: 700.94. | |
| Dactylocycline A | Dactylocycline is a tetracycline antibiotic produced by Dactylospoangium sp. Dactylocycline A has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity, and is not cross-resistant with tetracycline-resistant bacteria. Synonyms: 7-chloro-4-(dimethylamino)-3,4a,10,12,12a-pentahydroxy-6-((4-(hydroxyamino)-5-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-8-methoxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide. CAS No. 125622-12-0. Molecular formula: C31H40ClN3O13. Mole weight: 698.11. | |
| Dactylocycline B | Dactylocycline is a tetracycline antibiotic produced by Dactylospoangium sp. Dactylocycline B has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity, and is not cross-resistant with tetracycline-resistant bacteria. Synonyms: 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-methyl-1,11-dioxo-6-((2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitro-alpha-L-arabino-hexopyranosyl)oxy)-, (4R-(4alpha,4aalpha,5aalpha,6alpha,12aalpha))-; 7-chloro-4-(dimethylamino)-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-((5-methoxy-4,6-dimethyl-4-nitrotetrahydro-2H-pyran-2-yl)oxy)-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide. CAS No. 125622-13-1. Molecular formula: C31H38ClN3O14. Mole weight: 712.10. | |
| Dactylocycline D | Dactylocycline is a tetracycline antibiotic produced by Dactylospoangium sp. Dactylocycline D has anti-Gram-positive bacteria activity. Synonyms: 6-((4-(acetoxyamino)-5-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-chloro-4-(dimethylamino)-3,4a,10,12,12a-pentahydroxy-8-methoxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide. CAS No. 146064-00-8. Molecular formula: C33H42ClN3O14. Mole weight: 740.15. | |
| Dactylocycline E | Dactylocycline is a tetracycline antibiotic produced by Dactylospoangium sp. Dactylocycline E has anti-Gram-positive bacteria activity. CAS No. 146064-01-9. Molecular formula: C31H39ClN2O13. Mole weight: 683.11. | |
| D-Alanine methyl ester | D-Alanine methyl ester. CAS No. 21705-13-5. Molecular formula: C4H9NO2. Mole weight: 103.1. | |
| Dalbavancin hydrochloride | Dalbavancin is a semi-synthetic glycopeptide by introducing a positively charged lipophilic moiety in a previously unexplored region of the natural glycopeptide. This modification provides a longer in vivo half life, and improved in vitro activity against a variety of Gram-positive and multi-drug resistant isolates such as MRSA and MRSE. Synonyms: Dalbavancin HCl; Ristomycin A aglycone, 5,31-dichloro-38-de(methoxycarbonyl)-7-demethyl-19-deoxy-56-O-[2-deoxy-2-[(10-methyl-1-oxoundecyl)amino]-beta-D-glucopyranuronosyl]-38-[[[3-(dimethylamino)propyl]amino]carbonyl]-42-O-alpha-D-mannopyranosyl-N15-methyl-. CAS No. 2227366-51-8. Molecular formula: C88H101Cl3N10O28. Mole weight: 1853.1. | |
| Dalfopristin | A semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains. Synonyms: Dalfopristinum. Grade: >98% by HPLC. CAS No. 112362-50-2. Molecular formula: C34H50N4O9S. Mole weight: 690.85. | |
| Damavaricin D | Damavaricin D is an ansamycin antibiotic isolated from the Streptovaricin complex produced by Streptomyces spectabilis. It is the biosynthetic precursor of Streptomycin D, and also has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-fungal effects. CAS No. 59556-95-5. Molecular formula: C37H47NO12. Mole weight: 697.77. | |
| D-Arginine methyl ester | D-Arginine methyl ester. Synonyms: D-Arginine, methyl ester. CAS No. 65160-70-5. Molecular formula: C7H16N4O2. Mole weight: 188.2. | |
| D-Argininol | D-Argininol. Synonyms: H-D-Arg-ol. CAS No. 1313054-61-3. Molecular formula: C6H16N4O. Mole weight: 160.20. | |
| Darlucin A | Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin A has antibacterial and fungi activity, and weak cytotoxicity. CAS No. 162341-15-3. Molecular formula: C19H16N2O3. Mole weight: 320.34. | |
| Darlucin B | Darlucin is a diisocyanid compound produced by Darluca filum. Darlucin B has antibacterial and fungi activity, and weak cytotoxicity. CAS No. 162341-16-4. Molecular formula: C19H20N2O3. Mole weight: 324.37. | |
| D-Aspartamide | D-Aspartamide. CAS No. 114818-26-7. Molecular formula: C4H9N3O2. Mole weight: 131.1. | |
| D-Aspartic acid dimethyl ester | D-Aspartic acid dimethyl ester. Synonyms: dimethyl D-aspartate; (R)-Dimethyl 2-aminosuccinate; d-aspartic acid dimethyl ester. CAS No. 88067-96-3. Molecular formula: C6H11NO4. Mole weight: 161.20. | |
| Davercin | Erythromycin Cyclocarbonate, a derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome. Synonyms: Erythromycin A 11,12-carbonate; Erythromycin A cyclic 11,12-carbonate; Erythromycin cyclic carbonate. Grade: >98%. CAS No. 55224-05-0. Molecular formula: C38H65NO14. Mole weight: 759.92. | |
| DC-102 | DC-102 is produced by the strain of Streptomyces sp. It has anti-gram-positive bacteria activity and anti-tumor effect. Synonyms: DC 102 Antibiotic; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-7-((4,6-dideoxy-3-C-methyl-4-(methylamino)-alpha-L-mannopyranosyl)oxy)-11-methoxy-2-propylidene-. CAS No. 115722-50-4. Molecular formula: C24H35N3O6. Mole weight: 461.55. | |
| DC 81 | DC 81 is originally isolated from Streptomyces roseiscleroticus DO-81. It has weak anti-gram-positive, anti-gram-negative and tumor activity. Synonyms: Antibiotic DC 81; (+)-1,2,3,11a-Tetrahydro-8-hydroxy-7-methoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one; 7-Methoxy-8-hydroxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 8-hydroxy-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one. CAS No. 81307-24-6. Molecular formula: C13H14N2O3. Mole weight: 246.26. | |
| DC 86M | It is originally isolated from Streptomyces lugeogriseus 86. DC 86M has anti-Gram-positive bacteria and weak anti-Gram-negative bacteria activity, and can inhibit mouse sarcoma 180 cells. Synonyms: 6-(1-((Hydroxyacetyl)oxy)ethyl)-1-phenazinecarboxylic acid; DC-86-M; DC-86M; DC 86 M; 6-{1-[(Hydroxyacetyl)oxy]ethyl}phenazine-1-carboxylic acid. Grade: >98%. CAS No. 94448-15-4. Molecular formula: C17H14N2O5. Mole weight: 326.30. | |
| DC92-B | It is originally isolated from Actinomadura sp. DC92-B is mainly resistant to Gram-positive bacteria, and it also has anti-tumor activity. Synonyms: DC 92B; 4H-Anthra(1,2-b)pyran-4,7,12-trione, 11-hydroxy-5-methyl-8-(2,3,6-trideoxy-3-(dimethylamino)-beta-D-arabino-hexopyranosyl)-10-(2,3,6-trideoxy-3-(dimethylamino)-5-C-hydroxy-3-C-methylhexopyranosyl)-2-(3,3',3'-trimethyl(2,2'-bioxiran)-3-yl)-. Grade: >98%. CAS No. 116988-30-8. Molecular formula: C42H52N2O12. Mole weight: 776.87. | |
| DC92-D | It is originally isolated from Actinomadura sp. and DC92-D is mainly resistant to Gram-positive bacteria. Synonyms: DC 92D; 8-(4-(dimethylamino)-3-hydroxy-2-methyl-3,4-dihydro-2H-pyran-6-yl)-10-(3-(dimethylamino)-4,6-dihydroxy-3,6-dimethyltetrahydro-2H-pyran-2-yl)-11-hydroxy-5-methyl-2-(3,3',3'-trimethyl-[2,2'-bioxiran]-3-yl)-4H-naphtho[2,3-h]chromene-4,7,12-trione. CAS No. 116988-29-5. Molecular formula: C42H50N2O12. Mole weight: 774.85. | |
| D-Cysteinamide | D-Cysteinamide. Synonyms: 2-Amino-3-Mercapto-Propionamide. CAS No. 85950-54-5. Molecular formula: C3H8N2OS. Mole weight: 120.2. | |
| D-Cysteinol | D-Cysteinol. CAS No. 23517-29-5. Molecular formula: C3H9NOS. Mole weight: 107.2. | |
| Deacetyl 19,20-epoxycytochalasin Q | Deacetyl 19,20-epoxycytochalasin Q is a cytotoxic agent obtained from Xylaria obovata, which is a plant growth regulator. Synonyms: 3H-Oxireno[f]oxireno[9,10]cycloundec[1,2-d]isoindole-3,12(4H)-dione, 1a,2,5,7a,7b,8a,9,9a,10,11,13,13a-dodecahydro-2,13-dihydroxy-2,4,8a,9-tetramethyl-10-(phenylmethyl)-, (1aR,2R,4S,6E,7aR,7bS,8aR,9S,9aR,10S,12aR,13S,13aS)-; 2H-Oxireno[f]oxireno[9,10]cycloundec[1,2-d]isoindole-3,12(1aH,4H)-dione, 5,5a,6,6a,7a,7b,10,11,13,13a-decahydro-2,13-dihydroxy-6,6a,11,13-tetramethyl-5-(phenylmethyl)-, [1aS-(1aR*,2R*,2aS*,5R*,5aS*,6R*,6aS*,7aR*,7bS*,8E,11R*,13S*,13aS*)]- (9CI); [11]Cytochalas-13-ene-1,17-dione, 6,7:19,20-diepoxy-18,21-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19R,20S,21R)-; (1aR,2R,4S,6E,7aR,7bS,8aR,9S,9aR,10S,12aR,13S,13aS)-1a,2,5,7a,7b,8a,9,9a,10,11,13,13a-Dodecahydro-2,13-dihydroxy-2,4,8a,9-tetramethyl-10-(phenylmethyl)-3H-oxireno[f]oxireno[9,10]cycloundec[1,2-d]isoindole-3,12(4H)-dione; Deacetyl 19,20-epoxycytochalasin Q. CAS No. 156616-84-1. Molecular formula: C28H35NO6. Mole weight: 481.58. | |
| Deacetylchromomycin A3 | It is produced by the strain of marine-derived Streptomyces sp. SNB-005. Synonyms: Deacetyl Chromomycin A3; (2R,3R,4R,6S)-6-(((6S,7S)-7-((1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl)-6-(((2S,4S,5R,6R)-4-(((2S,4S,5R,6R)-4-(((2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4,10-dihydroxy-3-methyl-5-oxo-5,6,7,8-tetrahydroanthracen-2-yl)oxy)-4-(((2R,4R,5S,6R)-4-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-methyltetrahydro-2H-pyran-3-yl acetate; (1S)-1-C-[(2S,3S)-7-{[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-alpha-D-arabino-hexopyranosyl)-beta-D-arabino-hexopyranosyl]oxy}-3-{[2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl-(1->3)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->3)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-5,10-dihydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydro-2-anthracenyl]-5-deoxy-1-O-methyl-D-xylulose; Olivomycin D, 3D-O-(2,6-Dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-7-methyl-; NSC 270051. CAS No. 6992-71-8. Molecular formula: C55H80O25. Mole weight: 1141.21. | |
| Deacetylravidomycin M | Deacetylravidomycin M is an interleukin-4 signaling inhibitor produced by Streptomyces sp. WK-6326. It has little antibacterial activity, but it can inhibit the expression of CD23 induced by interleukin-4 in U937 cells, and has no cytotoxicity. Molecular formula: C28H31NO8. Mole weight: 509.55. | |
| Deacetylravidomycin N-oxide | Deacetylravidomycin N-oxide is an antibiotic produced by Streptomyces ravidus S50905. Activity against gram-positive bacteria. Deacetylravidomycin N-oxide can prolong the survival period of Meth A fibrosarcoma mice, but it is not effective for P815 mast cell tumor. Synonyms: Ravidomycin N-oxide; 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(4-O-acetyl-3,6-dideoxy-3-(dimethylamino)-alpha-altropyranosyl)-10,12-dimethoxy-8-ethenyl-1-hydroxy-, N-oxide. CAS No. 114494-30-3. Molecular formula: C31H33NO10. Mole weight: 579.59. | |
| Debromomarinone | Debromomarinone is a chemical compound isolated from marine actinomycetes. Synonyms: 4H-Benzo[d]naphtho[2.3-b]pyran-7,12-dione, 3,4a,5,12b-tetrahydro-8,10-dihydroxy-2,5-dimethyl-5-(4-methyl-3-penten-1-yl)-, (4aR,5S,12bS)-rel-. CAS No. 2378288-00-5. Molecular formula: C25H28O5. Mole weight: 408.49. | |
| Decanoyl-L-homoserine lactone | An active quorum sensing modulator first recognised in burkholderia pseudomallei. It is detected in hundreds of bacterial species. Synonyms: C10-HSL; N-Decanoyl-L-homoserine lactone; N-[(3S)-2-Oxotetrahydrofuran-3-yl]decanamide. Grade: >99% by HPLC. CAS No. 177315-87-6. Molecular formula: C14H25NO3. Mole weight: 255.35. | |
| Decaplanin | It is a kind of glycopeptide antibiotic originally isolated from Amycolatatopsis orientalis NCIB 12608 with good activity against Gram-positive bacteria. Synonyms: MM 47761; MM-47761; M86-1410; Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-D-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-19-dechloro-2'-O-(6-deoxy-alpha-D-talopyranosyl)-. CAS No. 126985-51-1. Molecular formula: C72H86ClN9O28. Mole weight: 1560.95. | |
| Decarboxy-2'-O-methyldivaricatic acid | It is a depside first isolated from the chloroform extract of the lichen Ramalina peruviana Ach. (Ramalinaceae). It belongs to Ramalina genus and is detected in the lichen Neofuscelia depsidella. Synonyms: Benzoic acid, 2-hydroxy-4-methoxy-6-propyl-, 3-methoxy-5-propylphenyl ester. Molecular formula: C21H26O5. Mole weight: 358.43. | |
| Decarboxy-2'-O-methylnorimbricaric acid | It is the new depside from the Lichen Neofuscelia depsidella. Synonyms: 3-methoxy-5-propylphenyl 2,4-dihydroxy-6-pentylbenzoate; Benzoic acid, 2,4-dihydroxy-6-pentyl-, 3-methoxy-5-propylphenyl ester. Molecular formula: C22H28O5. Mole weight: 372.45. | |
| Decarboxyalectoronic acid | Decarboxyalectoronic acid. Synonyms: 3,8-Dihydroxy-1,6-bis(2-oxoheptyl)-11H-dibenzo[b,e][1,4]dioxepin-11-one; 11H-Dibenzo[b,e][1,4]dioxepin-11-one, 3,8-dihydroxy-1,6-bis(2-oxoheptyl)-. CAS No. 184675-65-8. Molecular formula: C27H32O7. Mole weight: 468.54. | |
| Decarboxyanziaic acid | Decarboxyanziaic acid is a substance from the lichen neofuscelia depsidella. Molecular formula: C23H30O5. Mole weight: 386.5. | |
| Decarboxydivaricatic acid | Decarboxydivaricatic acid is a substance from the lichen neofuscelia depsidella. Molecular formula: C20H24O5. Mole weight: 344.4. | |
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