BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| dG-Thiophosphoramidite | dG-Thiophosphoramidite, a premium reagent, is widely utilized in biomedical research. Its application lies in the synthesis of DNA oligonucleotides equipped with thiophosphate links, rendering them incredibly potent agents for combating diseases such as cancer and viral infections, courtesy of enhanced nuclease resistance. Researchers entrust this reagent for its dependable performance as it is easily accessible and has a sound reputation. Synonyms: 5'-Dimethoxytrityl-N-isobutyryl-2'-deoxyGuanosine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C48H53N6O8PS2. Mole weight: 937.07. |  |
| Diaminopyrazine-C-nucleoside CEP | Acknowledged as an indispensable entity within the biomedical industry, diaminopyrazine-C-nucleoside CEP stands tall as a profound compound. Its offering extends far beyond its mere presence, encompassing an unparalleled influence in the realm of novel pharmaceutical interventions. A vast array of afflictions, including the notorious cancers and viral infections, succumb to its far-reaching medicinal dominion. Molecular formula: C57H82ClN8O6P. Mole weight: 1041.74. | |
| Diapausin precursor | Diapausin precursor is isolated from Spodoptera exigua. It has antimicrobial activity. | |
| Dicentracin precursor | Dicentracin precursor is isolated from Dicentrarchus labrax. It has antimicrobial activity. | |
| dI-CPG 1000 | dI-CPG 1000, a powerful synthetic immunostimulatory oligonucleotide that serves to activate the natural immune system. Its unique ability to act as a Toll-like receptor 9 (TLR9) agonist initiates the production of an array of cytokines and chemokines, which in turn create a domino effect that stimulates immune responses effectively. Its extensive application in cancer immunotherapy as an adjuvant and also as a vaccine adjuvant against a vast range of infectious diseases amplifies its importance in the scientific community. Synonyms: 5'-Dimethoxytrityl-2'-deoxyInosine, 3'-succinoyl-long chain alkylamino-CPG 1000. Mole weight: 314.19. | |
| dI-CPG 500 | dI-CPG 500, a fascinating synthetic molecule, is widely acknowledged as an immunostimulatory agent, leveraging Toll-like receptor 9 (TLR9) signaling to trigger immune responses in different cell types. Scientific studies propose dI-CPG 500's potential ability to be utilized as an adjuvant in cancer immunotherapy, with an emphasis on using it to treat ovarian and breast cancer. Moreover, research suggests that the molecule showcases promising prospects of treating infectious diseases such as hepatitis B and C and herpes simplex virus. Synonyms: 5'-Dimethoxytrityl-2'-deoxyInosine, 3'-succinoyl-long chain alkylamino-CPG 500. Mole weight: 314.19. | |
| Dicynthaurin | Dicynthaurin is isolated from Halocynthia aurantium. It shows antibacterial activity against both Gram-positive and Gram-negative bacteria. Dicynthaurin has no activity against the fungus C.albicans. Dicynthaurin has modest hemolytic activity. | |
| Digoxin NHS Ester | Digoxin NHS Ester, a chemical compound widely employed in the biomedical industry for protein labeling or modification, is actually a modified form of the familiar drug digoxin with the remarkable capacity to identify and quantify biological targets, including such notable entities as antibodies and receptors. It is often relied on in research pertaining to cancer and cardiovascular disease. Grades: >95% by HPLC. Molecular formula: C35H50N2O10. Mole weight: 658.79. | |
| Dihydrozeatin riboside-5'-monophosphate sodium salt | Dihydrozeatin riboside-5'-monophosphate sodium salt is a biomedical compound assuming a pivotal role in modulating distinct cellular signaling pathways. Synonyms: 6-(4-hydroxy-3-methylbutylamino)-9-b-D-ribofuranosyl purine-5'-monophosphate disodium monohydrate. Grades: ≥ 95% (TLC). CAS No. 31284-94-3. Molecular formula: C15H22N5Na2O8P·H2O. Mole weight: 495.33. | |
| Dimethyl DL-glutamate hydrochloride | Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes. It also potentiates the insulinotropic potential of glyburide and glucagon-like peptide Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells. Synonyms: Glutamic acid dimethyl ester; Dimethyl 2-aminopentanedioate; Dimethyl 2-aminopentanedioate hydrochloride; H-DL-Glu(OMe)-OMe.HCl; H-DL-Glu(Ome)-Ome. Grades: ≥ 98% (HPLC). CAS No. 13515-99-6. Molecular formula: C7H13NO4·HCl. Mole weight: 211.6. | |
| Dinoponeratoxin Da-1039 | Dinoponeratoxin Da-1039 has antibacterial activity. The source of Dinoponeratoxin Da-1039 is Dinoponera australis. Grades: >96% by HPLC. Molecular formula: C48H74N14O12. Mole weight: 1039.18. | |
| Dinoponeratoxin Da-1585 | Dinoponeratoxin Da-1585 has antibacterial activity. The source of Dinoponeratoxin Da-1585 is Dinoponera australis. Grades: >97% by HPLC. Molecular formula: C71H129N19O17S2. Mole weight: 1585.03. | |
| Dinoponeratoxin Da-3105 | Dinoponeratoxin Da-3105 has antibacterial activity. The source of Dinoponeratoxin Da-3105 is Dinoponera australis. | |
| Dinoponeratoxin Da-3177 | Dinoponeratoxin Da-3177 has antibacterial activity. The source of Dinoponeratoxin Da-3177 is Dinoponera australis. | |
| Diptericin | Diptericin is a 9 kDa antimicrobial peptide of flies first isolated from Sarcophaga peregrina. It is primarily active against Gram-negative bacteria, disrupting bacterial membrane integrity. | |
| Diquafosol Sodium Salt (90%) | Diquafosol Sodium Salt, is a dinucleoside derivative of uridine that acts as a selective P2Y2 receptor agonist. Diquafosol is used as a therapeutic agent in the treatment of dry eye syndrome. Synonyms: Uridine 5'-(Pentahydrogen Tetraphosphate), P'''?5'-Ester with Uridine Sodium Salt; P1,P4-Diuridine 5'-Tetraphosphate Sodium Salt. Grades: 90%. Molecular formula: C18H26N4O23P4 xNa. Mole weight: 790.31. | |
| Distinctin | The antimicrobial peptide distinctin consists of two peptide chains linked by a disulfide bridge. It presents a peculiar fold in water resulting from noncovalent dimerization of two heterodimeric molecules. | |
| Distinctin-like peptide | Distinctin-like peptide is produced by Phyllomedusa azurea. It has antimicrobial activity. | |
| Disulfo-Cyanine 7 Azide | Disulfo-Cyanine 7 Azide is a fluorescent dye used in biomedical applications such as labeling biomolecules for imaging. It can be conjugated to biomolecules via click chemistry and has excitation and emission wavelengths of 750 nm and 773 nm, respectively. Disulfo-Cyanine 7 Azide is also used in drug delivery systems and in cancer research. Synonyms: Potassium 3-[1-[1-(N-(3-azidopropyl)hexamid-6-yl)-2,3-dimethyl-5-sulfonato-indol-2-ylidene]-ethylidene]-cyclohexen-1-yl-ethynyl-2-(1,3,3-trimethylindolium-5-sulfonate. Molecular formula: C40H50KN6O7S2. Mole weight: 829.08. | |
| Dithioerythritol | Reagent for the reduction of disulfide group. Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis. Cleavage of disulfide bonds in proteins. Uses: White crystals. Synonyms: 1,4-Dithioerythritol; (2R,3S)-1,4-bis(sulfanyl)butane-2,3-diol. Grades: ≥98%. CAS No. 6892-68-8. Molecular formula: C4H10O2S2. Mole weight: 154.25. | |
| Dithiol Serinol Phosphoramidite | Dithiol Serinol Phosphoramidite is a key component in the synthesis of mRNA vaccines used to combat diseases like COVID-19. This compound provides a crucial thiol group that creates a stable linkage between mRNA and its delivery vehicle, enabling efficient cellular uptake and protein translation. Synonyms: 3-Dimethoxytrityloxy-2-(3-((R)-α-lipoamido)propanamido)propyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C44H61N4O7PS2. Mole weight: 853.08. | |
| dithymidine 3',5'-phosphate | Dithymidine 3',5'-phosphate, a biochemical of great scientific significance, features prominently in research circles as it allows the study of protein-DNA interactions and enzyme reactions. In addition, its synthesis of oligonucleotides proves instrumental in analyzing nucleic acid metabolism and DNA repair pathways. Its versatile properties make it an essential instrument of contemporary scientific pursuit. Synonyms: d(Tpt); thymidylyl(3'-5')thymidine; dTpdT DNA Dinucleotide (5'-3'). Grades: ≥95% by AX-HPLC. Molecular formula: C20H27N4O12P. Mole weight: 546.40. | |
| Divercin V41 | Divercin V41 is a new bacteriocin produced by Carnobacterium divergens V41, a lactic acid bacterium isolated from fish viscera. Synonyms: Divercin V41. Molecular formula: C55H79N13O15S2. Mole weight: 1226.4. | |
| dK-CE Phosphoramidite | dK-CE Phosphoramidite, a critical ingredient utilized in the creation of customized oligonucleotides, holds exceptional value within the biomedical realm, affording myriad benefits for the management of diverse viral ailments and cancers. Its proficiency is underscored by an elevated chemical yield and its minimal purification needs foster streamlined, cost-efficient production of therapeutic nucleic acids. Synonyms: 9-[2'-Deoxy-5'-dimethoxytrityl-ß-D-ribofuranosyl]-2-dimethylaminomethyleneamino-6-methoxyaminopurine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 136986-37-3. Molecular formula: C44H56N9O7P. Mole weight: 853.96. | |
| DL-α-Methylproline hydrobromide | Synonyms: α-Me-DL-Pro-OH HBr; (R,S)-2-Methyl-pyrrolidine-2-carboxylic acid hydrobromide. Grades: ≥ 98% (NMR). CAS No. 1346136-61-5. Molecular formula: C6H11NO2·HBr. Mole weight: 210.08. | |
| D-Leucinol | The alcohol form of D-Leucine, a dietary amino acid involved in human protein synthesis. Synonyms: 1-Pentanol, 2-amino-4-methyl-, (2R)-. Grades: ≥ 99 % (Assay). CAS No. 53448-09-2. Molecular formula: C6H15NO. Mole weight: 117.2. | |
| DLPC | DLPC (1,2-Dilauroyl-sn-glycero-3-phosphocholine) is a LRH-1 agonist and the dilauroyl diester of phosphatidylcholine, one of the most common cell membrane lipids. Synonyms: Dilauroyl phosphatidylcholine; 1,2-Didodecanoyl-sn-glycero-3-phosphocholine; 1,2-Dilauroyl-sn-glycero-3-PC; L-α-Dilauroyl Phosphatidylcholine; L-α-Dilauroylglyceryl-3-phosphorylcholine. Grades: ≥98%. CAS No. 18194-25-7. Molecular formula: C32H64NO8P. Mole weight: 621.83. | |
| DL-Serine | Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2. Synonyms: Serine; Serine, DL-; (±)-Serine; 2-Azaniumyl-3-hydroxypropanoate; DL-Ser; NSC 9960. Grades: ≥95%. CAS No. 302-84-1. Molecular formula: C3H7NO3. Mole weight: 105.09. | |
| [D-Lys3]-GHRP-6 | [D-Lys3]-GHRP-6 is an antagonist at the ghrelin receptor (GHS-R1a) (IC50 = 0.9 μM), and a GHRP-6 antagonist. Synonyms: [D-Lys3]-Growth Hormone Releasing Peptide-6. CAS No. 136054-22-3. Molecular formula: C49H63N13O6. Mole weight: 930.12. | |
| Dm-AMP1 | DmAMP1, an antifungal plant defensin from dahlia (Dahlia merckII), interacts with sphingolipids from Saccharomyces cerevisiae. | |
| dmf-5-Me-isodC-CE Phosphoramidite | DMF-5-Me-isodC-CE Phosphoramidite, a chemical reagent, finds its essential utility in oligonucleotide synthesis in biomedicine. To be precise, it plays a crucial role in integrating the modified nucleoside, 5-methyl-2'-deoxycytidine into oligonucleotides. This state-of-the-art approach has proven its efficacy in battling formidable diseases such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-5-methyl-N-dimethylformamidine-2'-deoxyisoCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C43H55N6O7P. Mole weight: 798.91. | |
| dmf-isodG-CE Phosphoramidite | DMF-isodG-CE Phosphoramidite, a reagent used in chemical synthesis of nucleosides and nucleotides for medicinal purposes, is applied in diagnostic and therapeutic arenas of biomedicine. Its primary capacity lies in the modification of DNA and RNA. By introducing 5'-DMF-isodG-CE, these molecules become more stable and specific, augmenting precision in assorted biological assays. Its clinical utilization has demonstrated efficacy against diseases such as cancer and genetic disorders. Synonyms: 5'-Dimethoxytrityl-O2-diphenylcarbamoyl-N6-dimethylaminomethylidene-2'-deoxyisoGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C56H62N9O8P. Mole weight: 1020.13. | |
| DMPC | DMPC (1,2-Dimyristoyl-sn-glycero-3-phosphocholine) is a synthetic phospholipid utilized in liposomes and lipid bilayers for the study of biological membranes. Synonyms: 1,2-Dimyristoyl-sn-glycero-3-PC; 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine; (R)-2,3-Bis(tetradecanoyloxy)propyl [2-(Trimethylammonio)ethyl] Phosphate. Grades: > 97.0% (T) (HPLC). CAS No. 18194-24-6. Molecular formula: C36H72NO8P. Mole weight: 677.93. | |
| DMPE | DMPE (1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine) is a high purity phospholipid utilized for liposome production. Synonyms: 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine. Grades: ≥98%. CAS No. 998-07-2. Molecular formula: C33H66NO8P. Mole weight: 635.85. | |
| D-NAME hydrochloride | N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME). D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Synonyms: D-NG-Nitroarginine methyl ester; N(G)-Nitro-D-Arginine methyl ester; D-NAME, NG-Nitro-D-arginine methyl ester hydrochloride. Grades: ≥95%. CAS No. 50912-92-0. Molecular formula: C7H15N5O4·HCl. Mole weight: 269.7. | |
| D-Norvalinol | D-Norvalinol (CAS# 80696-30-6) is a useful research chemical compound. Synonyms: H-D-Nva-ol; (R)-2-Amino-1-pentanol; (R)-2-Aminopentan-1-ol; (R)-(-)-2-Amino-1-pentanol; (2R)-2-aminopentan-1-ol. Grades: ≥ 98 %. CAS No. 80696-30-6. Molecular formula: C5H13NO. Mole weight: 103.17. | |
| DNP CE Phosphoramidite | DNP CE Phosphoramidite is a paramount compound, serving as a multifaceted and adaptable solution for the orchestrated fabrication of personalized DNA oligonucleotides. Its pivotal role as a phosphoramidite building component in solid-phase synthesis fosters the precise integration of a DNP moiety at designated locales within the DNA sequence. Grades: >95% by HPLC. Molecular formula: C21H34N5O6P. Mole weight: 483.51. | |
| DO3A tert-Butyl ester | DOTA tert-Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Synonyms: Tri-tert-butyl 1,4,7,10-tetraazacyclododecane-1,4,7-triacetate; DO3A-t-Bu-ester; 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Tri-tert-butyl Ester. Grades: >98%. CAS No. 122555-91-3. Molecular formula: C26H50N4O6. Mole weight: 514.70. | |
| Dolabellanin-B2 | Dolabellanin-B2 has antibacterial activity against Gram-negative bacteria E.coli JM109 and DH5-alpha, H.influenza IID 983, and V.vulnificus RIMD 2219009. Dolabellanin-B2 has antibacterial activity against Gram-positive bacteria S.aureus IID 1677, B.subtilis RIMD 0225014 and L.monocytogenes VIU206. It also possesses antifungal activity against S.cerevisiae A581A, S.pombe IFO 1628, C.albicans and TIMM-1623, and C.tropicalis TIMM-0313. | |
| Dominulin-A | Dominulin A has antibacterial activity. The source of Dominulin A is the social paper wasp, Polistes dominulus. Grades: >97% by HPLC. | |
| Dominulin-B | Dominulin-B shows antimicrobial activity against the Gram-positive bacteria B.subtilis, and the Gram-negative bacteria E.coli JM109 (MIC=8 μg/ml). | |
| dP-CE Phosphoramidite | dP-CE Phosphoramidite is a chemical compound widely used in the production of nucleic acid sequences for biomedical research. It is typically used as a building block for the synthesis of modified DNA or RNA that can be used for various applications including gene editing, drug development, and disease diagnosis. Its unique chemical properties make it highly efficient in the synthesis of oligonucleotides with enhanced binding affinity, specificity, and stability towards specific drugs or targets. Synonyms: 6H,8H-3,4-dihydro-pyrimido[4,5-c][1,2]oxazin-7-one, 8-[(5'-dimethoxytrityl-ß-D-deoxyribofuranosyl), 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C41H50N5O8P. Mole weight: 771.85. | |
| [D-p-Cl-Phe6,Leu17]-VIP | [D-p-Cl-Phe6,Leu17]-VIP is a selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM) with no activity at glucagon, secretin or GRF receptors. Synonyms: [D-p-Cl-Phe6, Leu17]-Vasoactive Intestinal Peptide human, porcine, rat. CAS No. 102805-45-8. Molecular formula: C148H239ClN44O42. Mole weight: 3342.24. | |
| DPDPE | DPDPE is a synthetic enkephalin peptide and acts as a δ-opioid receptor agonist. Opioid receptors are divided into three types called, μ, κ and δ, depending upon their ligands. DPDPE has greater than 250-fold selectivity for the δ-opioid receptor over the μ- and κ-opioid receptors in rat brain homogenates (Kis = 713 and >1,500 nM, respectively). Uses: Neurotransmitter agents. Synonyms: DPDPE; [D-Pen2,5]Enkephalin; [D-Pen2,D-Pen5]Enkephalin. Grades: ≥95%. CAS No. 88373-73-3. Molecular formula: C30H39N5O7S2. Mole weight: 645.79. | |
| D-Phenylalaninol | D-Phenylalaninol (CAS# 5267-64-1 ) is a useful research chemical. Synonyms: (R)-2-Amino-3-phenyl-1-propanol; D-Phe-ol; (R)-2-Amino-3-phenylpropan-1-ol; D(+)-Phenylalaninol; (+)-D-Phenylalaninol; (2R)-2-amino-3-phenylpropan-1-ol. Grades: > 95 % by HPLC. CAS No. 5267-64-1. Molecular formula: C9H13NO. Mole weight: 151.21. | |
| D-Phenylglycinol | A chiral building block for the synthesis of novel fluorescent chemosensors for amino acid. Synonyms: H-D-Phg-ol; (R)-2-Amino-2-phenylethanol; (R)-(-)-2-Phenylglycinol; (R)-2-Phenylglycinol. Grades: ≥ 99 %. CAS No. 56613-80-0. Molecular formula: C8H11NO. Mole weight: 137.2. | |
| DPPS | Synonyms: 3,3'-[(Diphenylsilylene)di-4,1-phenylene]bispyridine, Diphenyl-bis(4-(pyridin-3-yl)phenyl)silane. CAS No. 1152162-74-7. Molecular formula: C34H26N2Si. Mole weight: 490.67. | |
| D-Prolinol | A reagent used for asymmetric synthesis. Synonyms: (R)-2-Hydroxymethyl-pyrrolidine; (R)-2-Pyrrolidinemethanol; (R)-(-)-2-Pyrrolidinemethanol. Grades: > 95 % by HPLC. CAS No. 68832-13-3. Molecular formula: C5H11NO. Mole weight: 101.2. | |
| D-?Ribitol, 1, ?4-?anhydro-?5-?O-? [bis (4-?methoxyphenyl) ?phenylmethyl] ?-?2-?O-?methyl-?1-?C-?phenyl-?, 3-?[2-?cyanoethyl N, ?N-?bis (1-?methylethyl)?phosphoramidite]?, (1S)?- | D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-1-C-phenyl-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], (1S)- is an indispensable phosphoramidite with application in oligonucleotide synthesis enabling the intricate modification and functionalization of nucleic acids. Synonyms: (2R, 3R, 4S, 5S)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-methoxy-5-phenyltetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1418182-88-3. Molecular formula: C42H51N2O7P. Mole weight: 726.84. | |
| D-?Ribitol, 1, ?4-?anhydro-?5-?O-?[bis (4-?methoxyphenyl) ?phenylmethyl]?-?2-?O-?methyl-?, 3-?[2-?cyanoethyl N, ?N-?bis (1-?methylethyl)?phosphoramidite] | D-Ribitol, 1,4-anhydro-5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-methyl-, 3-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a phosphoramidite acting as a fundamental constituent in the intricate construction of oligonucleotides. Playing a crucial role in the modification of nucleic acids, it bestows researchers with the ability to delve into the complexities of RNA and DNA configurations. Synonyms: (2R, 3S, 4S)-2- ( (bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 1470023-72-3. Molecular formula: C36H47N2O7P. Mole weight: 650.74. | |
| D-?Ribitol, 1-?C-?(7-?aminoisothiazolo[4, ?3-?d]?pyrimidin-?3-?yl)?-?1, ?4-?anhydro-?, (1R)?- | D-Ribitol, 1-C-(7-aminoisothiazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-, (1R)- is a remarkable compound product, deftly targeting specific receptors and pathways, thereby engendering hope in studyting drug-resistant strains. CAS No. 1821192-02-2. Molecular formula: C10H12N4O4S. Mole weight: 284.29. | |
| Drosomycin | Drosomycin is an inducible antifungal peptide of 44 residues initially isolated from bacteria-challenged Drosophila melanogaster. Drosomycin exhibits a narrow antimicrobial spectrum and is only active against some filamentous fungi. | |
| Drosomycin-2 | Drosomycin-2 is an antiparasitic peptide which shows inhibitory effect on the ookinete development of the parasite Plasmodium berghei with differential potency. | |
| DRP-PBN1 | PBN1 is an antimicrobial peptide found in Phyllomedusa bicolor (South American two-colored leaf frog), and has antibacterial activity. Synonyms: PBN1; H-Phe-Leu-Ser-Leu-Ile-Pro-His-Ile-Val-Ser-Gly-Val-Ala-Ala-Leu-Ala-Lys-His-Leu-Gly-OH; Antimicrobial peptide, Dermaseptin-like peptide PBN1. Grades: ≥96%. Molecular formula: C97H159N25O23. Mole weight: 2043.48. | |
| D-Ser(Bzl)-ol HCl | Synonyms: O-Benzyl-D-serinol hydrochloride. Molecular formula: C10H15NO2·HCl. Mole weight: 217.69. | |
| DSP Crosslinker | DSP Crosslinker is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: Disuccinimido dithiobispropionate; Di(N-succinimidyl) 3,3'-dithiodipropionate. Grades: 98.0 %. CAS No. 57757-57-0. Molecular formula: C14H16N2O8S2. Mole weight: 404.42. | |
| dT-H-Phosphonate, TEA Salt | dT-H-Phosphonate, TEA Salt, is classified as a potent biomedical ingredient, used in research of anti-cancer regimens and nucleotide analog manipulation. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-H-phosphonate, TEA salt. Molecular formula: C37H48N3O9P. Mole weight: 709.78. | |
| dT-Me Phosphonamidite | The dT-Me Phosphonamidite, a reagent of exemplary quality, is a favored instrument in the synthesis of modulated oligonucleotides that can be leveraged to study the intricacies of gene expression and regulation. Its utilization in the creation of therapeutic agents meant to combat genetic maladies - including but not limited to the likes of cancer and viral infections - is an established norm. Its unmatched construction renders it exceptionally stable whilst augmenting binding affinity, ultimately rendering it a precious asset in the realm of biomedicine. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(methyl)-(N,N-diisopropyl)]-phosphonamidite. Molecular formula: C38H48N3O7P. Mole weight: 689.79. | |
| dT-PACE Phosphoramidite | dT-PACE Phosphoramidite is a vital constituent within the biomedical arena, serving as a pivotal recompound solely dedicated to the solid-phase synthesis of oligonucleotides. Proficiently facilitating the assimilation of dT-PACE is a distinctly altered nucleoside analog, into the intricate framework of oligonucleotide chains. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate. Molecular formula: C44H55N4O9P. Mole weight: 814.90. | |
| dT-Thiophosphoramidite | dT-Thiophosphoramidite, a chemical compound utilized in the synthetic process of oligonucleotides, characterized as a class of biomolecules with vast implications in the biomedical arena, specifically for diagnostics, gene therapy, and drug development, adds to the the structural and functional modification of oligonucleotides as an indispensable building block. Synonyms: 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(ß-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite; 5'-O- (4, 4'-Dimethoxytrityl) -3'-O-[pyrrolizino[[2- (benzoylthio) ethyl]thio]phosphino]thymidine. Molecular formula: C44H48N3O8PS2. Mole weight: 841.97. | |
| Duck AvBD9 | AvBD9 was differentially expressed in the tissues, with especially high levels of expression in liver, kidney, crop, and trachea. Duck AvBD9 exhibited antimicrobial activity against several bacterial strains. Synonyms: avian beta-defensins 9. | |
| dU-CPG 500 | dU-CPG 500, a synthetic oligonucleotide, is a robust immunostimulatory agent that has shown promising results in augmenting the immune response to vaccines and cancer immunotherapy. Additionally, its potential as a therapeutic agent to treat autoimmune and inflammatory diseases is the subject of ongoing investigations in the scientific community. Its versatility in these contexts attests to its potency as an indispensable tool for researchers and clinicians alike. Synonyms: 5'-Dimethoxytrityl-2'-deoxyUridine, 3'-succinoyl-long chain alkylamino-CPG 500. | |
| Duramycin | It is produced by the strain of Streptomyces cinnamomeus. It has activity against gram-positive bacteria, gram-negative bacteria (individual, weak), Mycobacterium and Candida albicans. Synonyms: 27, 46- (Methaniminopentaniminomethano) -6, 43: 15, 40-bis (methanothiomethano) pyrrolo [2, 1-d1] [1, 4, 7, 10, 13, 16, 19, 22, 2 5, 28, 31, 34, 37, 40, 43, 46, 49, 5 2] thiaheptadecaazacyclopentapentaco ntine, cyclic peptide deriv.; Antibiotic PA 48009; Lancovutide; Leucopeptin; Ancovenin, 2-L-lysine-6-(3-aminoalanine)-10-L-phenylalanine-12-L-phenylalanine-13-L-valine-15-(erythro-3-hydroxy-L-aspartic acid)-, cyclic 6-19)-imine; Duramycin A. Grades: ≥90%. CAS No. 1391-36-2. Molecular formula: C88H123N23O25S3. Mole weight: 1999.25. | |
| Duramycin B | Duramycins B is a new lanthionine containing antibiotic, has been isolated from Streptoverticillium strain R2075. Duramycins B is a potent inhibitor of human phospholipase A2. It exhibits only a weak antibacterial activity against B.subtilis, and does not display antimicrobial activity against S.aureus, S.mitis, E.coli, K.pneumoniae, P.vulgaris and C.albicans. Grades: ≥98%. CAS No. 132246-31-2. Molecular formula: C86H127N25O25S3. Mole weight: 2007.27. | |
| Duramycin C | Duramycin C is a new lanthionine containing antibiotic, has been isolated from Streptomyces griseoluteus (R2107). Duramycin C is a potent inhibitor of human phospholipase A2. It exhibits only a weak antibacterial activity against B.subtilis, and does not display antimicrobial activity against S.aureus, S.mitis, E.coli, K.pneumoniae, P.vulgaris and C.albicans. Grades: ≥98%. CAS No. 132268-38-3. Molecular formula: C82H115N23O27S3. Mole weight: 1951.12. | |
| D-Valinol | D-Valinol (CAS# 4276-09-9) is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer's disease. Synonyms: H-D-Val-ol; (R)-(-)-2-Amino-3-methyl-1-butanol. Grades: ≥ 99 % (GC). CAS No. 4276-9-9. Molecular formula: C5H13NO. Mole weight: 103.2. | |
| dW-CE Phosphoramidite | dW-CE Phosphoramidite, an invaluable reagent in the DNA synthesis process, boasts a dimethylaminopropyl modification that enables seamless coupling with other bases during solid-phase synthesis. Oligonucleotide therapeutics, extensively utilized to combat ailments as diverse as cancer and viral infections, owe their development to the consistent efficacy of this premium product. Synonyms: 3-Methyl-2-pivaloyloxy-5-[2'-deoxy-3'-O-(2-cyanoethyl-N,N-diisopropylamino)-phosphino-5'-O-(dimethoxytrityl)-beta-D-ribofuranos-1'-yl]-6-(triisopropylsilylethynyl)-pyridine. Molecular formula: C57H78N3O8PSi. Mole weight: 992.30. | |
| DX600 | DX600 is an inhibitor of angiotensin-converting enzyme 2 (ACE2). Synonyms: DX-600; Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2 (Disulfide bridge: Cys6-Cys17); N-{ [ (6S, 9R, 14R, 17S, 20S, 23S, 25aS, 31S, 34S, 37S, 40S, 42aS) -9- [ (N-Acetylglycyl-L-α -aspartyl-L-tyrosyl-L-seryl-L-histidyl) amino] -17- (4-aminobutyl) -37- (3-carbamimidamidopropyl) -31, 34-bis (4-hydroxybenzyl) -6- (hydroxymethyl) -20, 23-bis (1H-indol-3-ylmethyl) -40-isobutyl-5, 8, 16, 19, 22, 25, 30, 33, 36, 39, 42-undecaoxooctatriacontahydro-1H, 13H-dipyrrolo [2, 1-p: 2', 1'-e1] [1, 2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32, 35] dithiaundecaazacyclooctatriacontin-14-yl] carbonyl}-L-threonyl-L-tyrosyl-L-prolyl-L-α -aspartyl-L-prolyl-L-α -glutamylglycylglycylglycinamide; N-acetyl-glycyl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-histidyl-L-cysteinyl-L-seryl-L-prolyl-L-leucyl-L-arginyl-L-tyrosyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-tryptophyl-L-lysyl-L-cysteinyl-L-threonyl-L-tyrosyl-L-prolyl-L-alpha-aspartyl-L-prolyl-L-alpha-glutamyl-glycyl-glycyl-glycinamide (6->17)-disulfide. Grades: ≥95%. CAS No. 478188-26-0. Molecular formula: C141H185N35O40S2. Mole weight: 3074.32. | |
| dX-CE Phosphoramidite | dX-CE Phosphoramidite, an indispensable reagent for DNA and RNA synthesis, possesses a phosphoramidite moiety, a chemical group facilely inserted into oligonucleotides for solid-phase synthesis. With superior quality, dX-CE Phosphoramidite transforms DNA and RNA sequences alike, thus arming researchers with an irreplaceable implement to investigate gene expression, drug discovery, and genetic engineering. Synonyms: 5'-(4,4'-Dimethoxytrityl)-2,6-O-bis(2-(4-nitrophenyl)ethyl)-2'-deoxyXanthosine, 3'-[(2-cyanoethyl)-N,N-diisopropyl)]-phosphoramidite. Molecular formula: C56H61N8O12P. Mole weight: 1069.10. | |
| Dybowskin-1CDYa | Dybowskin-1CDYa is an antimicrobial peptide produced by Rana dybowskii. It has activity against the Gram-positive bacterium S.aureus (MIC=6 μM) and the Gram-negative bacterium E.coli (MIC=3 μM). Dybowskin-1CDYa lacks hemolytic activity against human erythrocytes. | |
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