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Enterocin P precursor
Enterocin P precursor is an antibacterial peptide isolated from Enterococcus faecium. Synonyms: preEntP.
Enterocin Q
Enterocin Q is an antibacterial peptide isolated from Enterococcus faecium.
Enterocin RJ-11
Enterocin RJ-11 is an antibacterial peptide isolated from Enterococcus faecium. Enterocin RJ-11 also effectively inhibited a spore-forming Bacillus that often contaminates food production processes.
Enterocin SE-K4
Enterocin SE-K4 is an antibacterial peptide isolated from Enterococcus faecium.
Enterocin X
Enterocin X, a novel two-peptide bacteriocin from Enterococcus faecium KU-B5, has an antibacterial spectrum entirely different from those of its component peptides.
Enterocin X beta
Enterocin X beta has antibacterial activity. Enterocin X beta was found in Enterococcus faecium KU-B5. Grades: >97% by HPLC. Molecular formula: C187H293N53O49. Mole weight: 4067.64.
Entianin
Entianin is a novel subtilin-like lantibiotic from Bacillus subtilis subsp. spizizenii DSM 15029T with high antimicrobial activity. Molecular formula: C150H247N39O46S5. Mole weight: 3493.12.
ent-Lamivudine Triphosphate Triethylammonium Salt
ent-Lamivudine Triphosphate Triethylammonium Salt is a metabolite of Lamivudine, a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has also been used for treatment of chronic hepatitis B. Synonyms: ((2R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl Tetrahydrogen Triphosphate Triethylammonium Salt. Grades: 96%. Molecular formula: C8H14N3O12P3S.xC6H15N. Mole weight: 469.20 (free acid).
ent-Sofosbuvir Desphosphate
ent-Sofosbuvir Desphosphate is a possible metabolite of prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
EP2
EP2 belongs to the antibacterial vermipeptide family (AVPF). It has antimicrobial activity. The source of EP2 is Eisenia fetida. Molecular formula: C26H43N5O10S. Mole weight: 617.71.
EP2B protein
EP2B is an antimicrobial protein produced by Macaca mulatta.
EP3
EP3 belongs to the antibacterial vermipeptide family (AVPF). It has antimicrobial activity. EP3 was found in Eisenia fetida.
EP5-1
EP5-1 belongs to the antibacterial vermipeptide family (AVPF). It has antibacterial activity. EP5-1 was found in Eisenia foetida. Molecular formula: C14H26N6O6S. Mole weight: 406.46.
Epicidin 280
Epicidin 280 is a novel type A lantibiotic produced by Staphylococcus epidermidis BN 280.
Epidermin
Epidermin is a type A lantibiotic that is a tetracyclic 21-amino-acid peptide which contains meso-lanthionine, 3-methyllanthionine, and S-(2-aminovinyl)-D-cysteine. It is obtained from Staphylococcus epidermidis Tue 3298 and exhibits antibiotic activity against many Gram-positive bacteria. It has a role as a metabolite and an antibacterial agent. Synonyms: Staphylococcin 1580. CAS No. 99165-17-0. Molecular formula: C98H141N25O23S4. Mole weight: 2165.58.
Epilancin 15X
Epilancin 15X is a novel lantibiotic from a clinical strain of Staphylococcus epidermidis.
Epinecidin-1
Epinecidin-1 is a highly potent marine antimicrobial peptide with anticancer and immunomodulatory activities. The synthetic peptide Epinecidin-1 has the potential to serve as a therapeutic drug used against bacterial infectious diseases. It also showed antiviral activity against non-enveloped, spherical virus (betanodavirus). Molecular formula: C114H176N30O21S. Mole weight: 2334.86.
epoxyqueuosine
Epoxyqueuosine is a crucial compound used in biomedical field for the development of drugs to study antibiotic-resistant bacterial infections. It plays a vital role in synthesizing modified queuosine, which enhances the efficacy of antibiotics against resistant pathogens. Synonyms: 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-5-[[(3,4-dihydroxy-6-oxobicyclo[3.1.0]hex-2-yl) amino]methyl]-1,7-dihydro-7-b-D-ribofuranosyl-; 7-(5-((2,3-Epoxy-4,5-dihydroxycyclopent-1-yl)amino)methyl)-7-deazaguanosine; 6-Amino-3-(((3,4-dihydroxy-6-oxabicyclo(3.1.0)hex-2-yl)amino)methyl)-1,5-dihydro-1-beta-D-ribofuranosyl-4H-pyrrolo(2,3-d)pyrimidin-4-one. Grades: ≥98%. CAS No. 107865-20-3. Molecular formula: C17H23N5O8. Mole weight: 425.4.
ε-5'-dAMP
ε-5'-dAMP is a fluorescent analogue of 2'-deoxyadenosine-5'-monophosphate. Synonyms: 2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97 % by HPLC. CAS No. 60508-81-8. Molecular formula: C12H14N5O6P (free acid). Mole weight: 355.3 (free acid).
ε-ADPR
ε-ADPR is a fluorescent analogue of ADP-ribose (λexc300 nm, λem410 nm) which is used in fluorometric assays. Synonyms: 1, N6- Ethenoadenosine- 5'- O- diphosphoribose, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 69699-76-9. Molecular formula: C17H23N5O14P2 (free acid). Mole weight: 583.3 (free acid).
ε-ADPRP
ε-ADPRP is a metabolite of ε-NADP+ and ε-NAADP+. Synonyms: 1, N6- Ethenoadenosine- 5'- O- diphosphoribose phosphate. Grades: ≥ 95% by HPLC. CAS No. 98088-66-5. Molecular formula: C17H24N5O17P3 (free acid). Mole weight: 663.3 (free acid).
ε-cAMP
ε-cAMP is a fluorescent cAMP analogue. Synonyms: 1, N6- Ethenoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 103213-51-0. Molecular formula: C12H11N5O6P ยท Na. Mole weight: 375.21.
ε-dATP
ε-dATP is a fluorescent dATP analogue. Synonyms: 2'- Deoxy- 1, N6- ethenoadenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 81004-54-8. Molecular formula: C12H16N5O12P3 (free acid). Mole weight: 515.2 (free acid).
ε-NAADP?
ε-NAADP+ is a fluorescent analogue of the Ca2+ -releasing messenger β-NAADP+, the Ca2+ -releasing messenger. Synonyms: β- Nicotinic acid- 1, N6- ethenoadenine dinucleotide phosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 217313-72-9. Molecular formula: C23H27N6O18P3 (free acid). Mole weight: 768.4 (free acid).
ε-NADP?
ε-NADP? is a fluorescent analogue of β-NADP+(λexc300 nm, λem410 nm), which can be used for analysis of binding and coenzyme activity of β-NADP+. Synonyms: β- Nicotinamide- 1, N6- ethenoadenine dinucleotide phosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 104809-28-1. Molecular formula: C23H28N7O17P3 (free acid). Mole weight: 767.4 (free acid).
Ericin A
Ericin A is a bacteriocin from Bacillus subgroups that has been reported to only inhibit the growth of gram-positive bacteria.
Ericin S
Ericin S is a bacteriocin from Bacillus subgroups that has been reported to only inhibit the growth of gram-positive bacteria.
Eryngin
An antifungal peptide with a molecular mass of 10k Da was isolated from fruiting bodies of the mushroom Pleurotus eryngii. The peptide, designated as eryngin, inhibited mycelial growth in Fusarium oxysporum and Mycosphaerella arachidicola.
Esculentin-1ARb is isolated from the crawfish frog, Rana areolata. It shows antibacterial activity against Gram-negative and Gram-positive bacterial species. It also has anti-HIV activity. Molecular formula: C226H381N59O61S3. Mole weight: 4996.98.
Esculentin-1B
Esculentin-1B is an antimicrobial peptide from Pelophylax saharicus (Sahara frog). It stimulates insulin secretion by BRIN-BD11 cells in vitro.
ETD130
ETD130 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=1.56 microg/ml), A. fumigatus GASP4707 (MIC50=25 microg/ml).
ETD131
ETD131 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=3.125 microg/ml), A. fumigatus GASP4707 (MIC50=3.125 microg/ml), C. neoformans A (MIC50=12.5 microg/ml).
ETD132
ETD132 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=6.25 microg/ml), A. fumigatus GASP4707 (MIC50=6.25 microg/ml).
ETD133
ETD133 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=6.25 microg/ml), A. fumigatus GASP4707 (MIC50=12.5 microg/ml).
ETD134
ETD134 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=1.56 microg/ml), A. fumigatus GASP4707 (MIC50=3.125 microg/ml).
ETD135
ETD135 is a synthetic construct peptide. It has antifungal activity.
ETD140
ETD140 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=3.125 microg/ml), A. fumigatus GASP4707 (MIC50=12.5 microg/ml).
ETD150
ETD150 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=3.125 microg/ml), A. fumigatus GASP4707(MIC50=6.25 microg/ml).
ETD151
ETD151 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=3.125 microg/ml), C. albicans No. 245962 (MIC50=0.4 microg/ml) , A. fumigatus GASP4707 (MIC50=6.25 microg/ml), C. neoformans A (MIC50=1.56 microg/ml) , F. solani FFUS 8591 (MIC50=0.4 microg/ml) and S. prolificans FSSP 8591 (MIC=0.1 microg/ml).
ETD152
ETD152 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=3.125 microg/ml), A. fumigatus GASP4707(MIC50=25 microg/ml).
ETD154
ETD154 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=6.25 microg/ml), A. fumigatus GASP4707(MIC50=12.5 microg/ml).
ETD156
ETD156 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=3.125 microg/ml), A. fumigatus GASP4707(MIC50=25 microg/ml).
ETD179
ETD179 is a synthetic construct peptide. It has antifungal activity against C. albicans IHEM 8060 (MIC50=1.56 microg/ml), A. fumigatus GASP4707 (MIC50=12.5 microg/ml).
Etheno-dA-CE Phosphoramidite
Etheno-dA-CE Phosphoramidite, a phosphoramidite chemical compound, finds critical application in synthesizing modified nucleotides for scientific investigations on cellular biology. More specifically, the compound participates in the synthesis of etheno-modified deoxyadenosine (etheno-dA), which enables researchers to examine the molecular effects of DNA damage and repair in instances of afflictions like cancer. Synonyms: 5'-Dimethoxytrityl-etheno-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. CAS No. 160702-08-9. Molecular formula: C42H48N7O6P. Mole weight: 777.86.
Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate
HOCt is a triazole-based coupling reagent that is used in solid-phase peptide synthesis with Fmoc-protected amino acids. Synonyms: 1-Hydroxy-1H-1,2,3-triazole-4-carboxylic Acid Ethyl Ester; ethyl 1-hydroxytriazole-4-carboxylate; 1H-1,2,3-Triazole-4-carboxylic acid, 1-hydroxy-, ethyl ester; HOCT [Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate]; ACMC-209cav; KSC497A3R; SCHEMBL4532875; AC-7874; AM83835; AK-58693; HOCT. Grades: 99 % (HPLC). CAS No. 137156-41-3. Molecular formula: C5H7N3O3. Mole weight: 157.13.
Ethyl 5-(4-fluorophenyl)isoxazole-3-carboxylate (CAS# 640291-92-5 ) is a useful research chemical. Synonyms: ethyl 5-(4-fluorophenyl)-1,2-oxazole-3-carboxylate. CAS No. 640291-92-5. Molecular formula: C12H10FNO3. Mole weight: 235.21.
Ethyl Adenosine-5'-carboxylate Hydrochloride
Ethyl Adenosine-5'-carboxylate Hydrochloride is an intermediate in the synthesis of Adenosine 5'-Monophosphate-5',5''-d2 Disodium Salt. Adenosine 5'-Monophosphate-5',5''-d2 Disodium Salt is the isotope labelled analogue of Adenosine 5'-Monophosphate, a nucleotide that is used as a monomer in RNA. Synonyms: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-β-D-ribofuranuronic Acid Ethyl Ester Monohydrochloride; Adenosine-5'-ethyl Carboxylate Hydrochloride; Adenosine-5'-carboxylic Acid Ethyl Ester Hydrochloride; NSC 161519. CAS No. 50663-70-2. Molecular formula: C12H15N5O5 HCl. Mole weight: 309.28.
Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is an indispensible compound, catering to the synthesis of modified oligonucleotides. Its application in drug R&D facilitates the investigation of nucleic acid interactions and chemical alterations. CAS No. 1173797-55-1. Molecular formula: C37H45N2O6P. Mole weight: 644.74.
Eumenine mastoparan-AF
Eumenine mastoparan-AF was isolated from the venom of the solitary wasp Anterhynchium flavomarginatum micado, the most common eumenine wasp found in Japan. It is a mast cell degranulating peptide. It has little hemolytic activity. Eumenine mastoparan-AF has an amphiphilic alpha-helix conformation. Eumenine mastoparan-AF shows broad-spectrum antimicrobial activity against the Gram-positive bacteria S.aureus, S.saprophyticus CS (MIC=5 μg/ml), S.epidermidis CS (MIC=5 μg/ml), B.subtilis CCT 2471 (MIC=40 μg/ml), and the Gram-negative bacteria E.coli CCT 1371 (MIC=20 μg/ml), E.coli, and P.aeruginosa. Synonyms: EMP-AF.
Eumenine mastoparan-EF
Eumenine mastoparan-EF is a linear cationic alpha-helical peptide that acts as an antimicrobial peptide by forming pore in membrane. It has antibacterial activity against both Gram-positive and Gram-negative strains. Eumenine mastoparan-EF has more potent activities against the yeast C.albicans. It shows moderate mast cell degranulation and leishmanicidal activities and has a very low hemolytic activity. Synonyms: EMP-EF.
Eumenine mastoparan-ER
Eumenine mastoparan-ER is a linear cationic alpha-helical peptide that acts as an antimicrobial peptide by forming pore in membrane. It has antibacterial activity against both Gram-positive and Gram-negative strains. Eumenine mastoparan-ER has more potent activities against the yeast C.albicans. It shows moderate mast cell degranulation and leishmanicidal activities and has a very low hemolytic activity. Synonyms: EMP-ER.
Eumenine mastoparan-OD
Eumenine mastoparan-OD has potent hemolytic activity against ovine erythrocytes at micromolar concentrations. It also exhibits strong antimicrobial activity against the fungi C.albicans and B.cinerea, and weaker activity against the Gram-negative bacterium E.coli and Gram-positive bacterium S.aureus. Synonyms: EMP-OD.
Eumenitin
Eumenitin is a cationic linear alpha-helical antimicrobial peptide that binds preferentially to charged lipid membranes as compared with zwitterionic ones. It exhibits inhibitory activity against both Gram-positive and Gram-negative bacteria, and moderately stimulates degranulation from the rat peritoneal mast cells. Eumenitin does not show hemolytic activity. It may play a role in preventing infection by microorganisms during prey consumption by their larvae. Grades: >97% by HPLC. Molecular formula: C78H137N19O19. Mole weight: 1645.03.
Eurocin
Eurocin acts against a range of Gram-positive human pathogens but not against Gram-negative bacteria.
European bumblebee abaecin
European bumblebee abaecin is a Pro-rich peptide. It is active against B. negaterium (MIC=10 ug/ml), E. coli, and A. tumefaciens (25 ug/ml). The source of European bumblebee abaecin is Bombus pascuorum (Hymenoptera, Apoidea). Grades: >98% by HPLC.
Exenatide
Exenatide, naturally occured in the saliva of the Gila monster, an incretin mimetic that has glucoregulatory effect. As a glucagon-like peptide-1 (GLP-1) receptor agonist, it stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways. Uses: Hypoglycemic agents. Synonyms: L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-; L-Histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide; Exendin 3 (Heloderma horridum), 2-glycine-3-L-glutamic acid-; Exendin 4 (Heloderma suspectum); AC 2993; AC 2993A; AC 2993LAR; Bydureon; Byetta; DA 3091; EQW; Exatenide; Exenatide LAR; Exendin 4; Exendin-4; ITCA 650; LAEx4; H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. CAS No. 141758-74-9. Molecular formula: C184H282N50O60S. Mole weight: 4186.56.
Exherin trifluoroacetate
Exherin trifluoroacetate is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities, which selectively and competitively binds to and blocks N-cadherin. Synonyms: ADH-1 trifluroacetate. Grades: >98%. CAS No. 1135237-88-5. Molecular formula: C24H35F3N8O8S2. Mole weight: 684.71.
EZ Cap Reagent GG
EZ Cap Reagent GG is a co-transcription capping reagent. Synonyms: EZ Cap Reagent GG for co-transcriptional capping of mRNA; m7G(5')ppp(5')(2'OMeG)pG. Grades: ≥95% by AX-HPLC. Molecular formula: C33H45N15O24P4. Mole weight: 1161.6.
EZ Cap Reagent GG (3' OMe)
EZ Cap Reagent GG (3'OMe) is a co-transcription capping reagent. Synonyms: EZ Cap Reagent GG (3' OMe) for co-transcriptional capping of mRNA; m7(3'OMeG)(5')ppp(5')(2'OMeG)pG. Grades: ≥95% by AX-HPLC. Molecular formula: C33H45N15O25P4. Mole weight: 1175.6.
Fa-AMP1
Fa-AMP1 is produced by Fagopyrum esculentum. The concentration of peptide required for 50% inhibition (IC50) of the growth of plant pathogenic fungi, and Gram-positive and -negative bacteria is 11 to 36 microg/ml. Mole weight: 3879.
Fa-AMP2
Fa-AMP2 is produced by Fagopyrum esculentum. The concentration of peptide required for 50% inhibition (IC50) of the growth of plant pathogenic fungi, and Gram-positive and -negative bacteria is 11 to 36 microg/ml. Mole weight: 3906.
Fabatin-1
Fabatin-1 is active against both Gram-negative and Gram-positive bacteria, but is inactive against the yeasts Saccharomyces cerevisiae and Candida albicans.
Fabatin-2
Fabatin-2 is active against both Gram-negative and Gram-positive bacteria, but is inactive against the yeasts Saccharomyces cerevisiae and Candida albicans.
FALL-39
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis.
Fallaxidin-3.1
Fallaxidin-3.1 was found in Litoria fallax. It has antibacterial activity.
Fallaxidin 3.2
Fallaxidin 3.2 has antibacterial activity. Fallaxidin 3.2 was found in Litoria fallax [Eastern dwarf tree frog].
Fallaxidin 4.1
Fallaxidin 4.1 was found in Litoria fallax. Fallaxidin 4.1 has antibacterial activity against L.lactis (MIC = 12 microM), M.luteus (MIC = 100 microM), S.epidermidis (MIC = 100 microM), and S.uberis (MIC = 50 microM).
FDMT-N2-iBu-dG CEP
FDMT-N2-iBu-dG CEP, an indispensable asset within the biomedical field, stands at the forefront of research endeavors. As a derivative nucleoside analogue, it houses the quintessential CEP (Cytidine 5'-O-(1,2-dihydroxypropyl) phosphoramidite) moiety. CAS No. 865758-46-9. Molecular formula: C54H57F17N7O8P. Mole weight: 1286.02.