BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
2'-(N-Hexadecanoylamino)-4'-nitrophenyl-b-D-glucopyranoside is a biomedical compound used to study enzyme reactions particularly involving glycosidases and esterases, and frequently used in research in the area of drug metabolism and absorption studies. Synonyms: N-[2-(beta-D-glucopyranosyloxy)-5-nitrophenyl]palmitamide; N-(2-(beta-D-Glucopyranosyloxy)-5-nitrophenyl)palmitamide; 2-Hexadecanoylamino-4-nitrophenyl-D-glucopyranoside; N-[2-(Hexopyranosyloxy)-5-nitrophenyl]hexadecanimidic acid; Hexadecanamide, N-(2-(beta-D-glucopyranosyloxy)-5-nitrophenyl)-; 2'-(N-HEXADECANOYLAMINO)-4'-NITROPHENYL-BETA-D-GLUCOPYRANOSIDE; N-(5-Nitro-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)palmitamide. CAS No. 61443-58-1. Molecular formula: C28H46N2O9. Mole weight: 554.67.
2-(N,N-Dimethylamino)-N6,N6-dimethyladenosine
2-(N,N-Dimethylamino)-N6,N6-dimethyladenosine, a compound under scrutiny for its therapeutic potential in alleviating neurodegenerative diseases like Alzheimer's, has exhibited immense promise in repressing the creation of amyloid-beta plaques in the brain - a signature hallmark of Alzheimer's disease. This versatile compound has also been extensively examined for its efficacy in cancer treatment. Synonyms: 2-(n,n-dimethylamino)-n6,n6-dimethyladenosine; 2305415-86-3. Grade: ≥95%. CAS No. 2305415-86-3. Molecular formula: C14H22N6O4. Mole weight: 338.36.
2-(N-Octylcarboamido)phenyl-2-acetamido-2-deoxy-b-D-glucopyranoside is widely used in the research and development of influenza drugs and may inhibit other viruses that share the salivary glycan receptors pathway. Molecular formula: C23H36N2O8. Mole weight: 468.54.
2-(N-Octylcarboamido)phenyl-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a specialized biomedical compound. It's prominent in medicinal chemistry research, mainly aiding in the development of new drugs intended for the treatment and management of diabetes and related conditions. Molecular formula: C29H42N2O11. Mole weight: 594.65.
2-(n-Propylidenehydrazino)adenosine
2-(n-Propylidenehydrazino)adenosine, a powerful and unprecedented adenosine receptor agonist, boasts a wealth of therapeutic potentialities for ailments like cancer and neurological disorders. Specifically, its exceptional capacity for stymieing the progression of cancer cells renders it game-changing in the treatment of multiple forms of cancer, while its ability to regulate neurotransmitter release endows it with the ability to ameliorate symptoms of neurodegenerative diseases like Parkinson's disease and epilepsy. Synonyms: 2-[(2E)-2-Propylidenehydrazino]adenosine; Adenosine, 2-[(2E)-2-propylidenehydrazinyl]-; 2-(n-Propylidene-hydrazino)adenosine. Grade: ≥95%. Molecular formula: C13H19N7O4. Mole weight: 337.33.
2'-(O-Allyl)-adenosine
2'- (O-Allyl)-adenosine is a nucleoside, displaying potent cytotoxic predilections. This molecular agent can impede the proliferative capabilities of considerable cancerous cell typologies. Grade: ≥ 98% by HPLC. Molecular formula: C13H17N5O4. Mole weight: 307.31.
2'-(O-Allyl)-cytidine
2'-(O-Allyl)-cytidine is a modified nucleoside commonly utilized in the biomedical realm. It's primarily used in anti-cancer research, playing a role in drug delivery systems aimed at the targeted destruction of malignant cells. Grade: ≥ 98% by HPLC. Molecular formula: C12H17N3O5. Mole weight: 283.28.
2'-(O-Allyl)-guanosine
2'-(O-Allyl)-guanosine is an intermediate in the research of select anti-cancer pharmaceutical concoctions. Grade: ≥ 98% by HPLC. Molecular formula: C13H17N5O5. Mole weight: 323.3.
2'-(O-Allyl)-uridine
2'-(O-Allyl)-uridine is a modified nucleoside often used in research of various viral diseases like Hepatitis C. Acting as a critical component in Ribavirin, it exhibits antiviral activities targeting a broad spectrum of RNA and DNA viruses. Grade: ≥ 98% by HPLC. Molecular formula: C12H16N2O6. Mole weight: 284.27.
2'-(O-Methyl)-5-iodo-uridine
2'-(O-Methyl)-5-iodo-uridine is a biochemical applied in the research and development of antiviral drugs, particularly against influenza viruses. Grade: ≥ 98% by HPLC. Molecular formula: C10H13IN2O6. Mole weight: 384.12.
2'-(O-Methyl)-5-methyl-cytidine
2'-(O-Methyl)-5-methyl-cytidine is an altered nucleoside, earmarking its utility in delineating RNA methylation studies. Grade: ≥ 98% by HPLC. Molecular formula: C11H17N3O5. Mole weight: 271.27.
2'-(O-Methyl)-5-propynyl-cytidine
2'-(O-Methyl)-5-propynyl-cytidine is an analog of cytidine, mainly used for research in antiviral treatment. Its altered structure could inhibit viral RNA replication, potentially curbing diseases like hepatitis C and influenza. Grade: ≥ 98% by HPLC. Molecular formula: C13H17N3O5. Mole weight: 295.29.
2'-(O-Methyl)-5-propynyl-uridine
2'-(O-Methyl)-5-propynyl-uridine is a uridine derivative used in the research and development of antiviral drugs, specifically against Hepatitis C. It acts as a potent inhibitor of HCV replication and showcases a strong broad-spectrum antiviral activity. Grade: ≥ 98% by HPLC. Molecular formula: C13H16N2O6. Mole weight: 296.28.
2'-(O-Methyl)-adenosine
2'-(O-Methyl)-adenosine is a methylation product used in biomedical research towards understanding RNA's functional modifications. It aids in studies of neuropsychiatric conditions and autoimmune diseases, focusing on utilizing RNA modification detection. Grade: ≥ 98% by HPLC. Molecular formula: C11H15N5O4. Mole weight: 281.27.
2'-(O-Methyl)-cytidine
2'-(O-Methyl)-cytidine is a nuanced nucleoside modification, having pronounced applications in the research and development of antiviral medicaments. Grade: ≥ 98% by HPLC. Molecular formula: C10H15N3O5. Mole weight: 257.24.
2'-(O-Methyl)-guanosine
2'-(O-Methyl)-guanosine is a modified guanosine used mostly in molecular biology studies. It is involved in the biological regulation of RNA structures and protein synthesis. It has potential therapeutic applications in research of viral disease and neurodegenerative disorders. Grade: ≥ 98% by HPLC. Molecular formula: C11H15N5O5. Mole weight: 297.27.
2'-(O-Methyl)-uridine
2'-(O-Methyl)-uridine is a modified nucleoside employed in biomedical sectors, fulfilling an elemental part within the exploration and regulation operations of RNA. Its significance emanates from its utilitarian approach towards pathologies instigated by RNA viruses, exemplified by Hepatitis C and HIV. Grade: ≥ 98% by HPLC. Molecular formula: C10H14N2O6. Mole weight: 258.23.
2'-(O-Propargyl)-adenosine
2'-(O-Propargyl)-adenosine is a biochemical agent widely used in biomedical research. The product plays a critical role in modulating Adenosine Receptors, and it's commonly used in experiments aimed at treating cardiovascular diseases, neurological disorders, and cancer. Grade: ≥ 98% by HPLC. Molecular formula: C13H15N5O4. Mole weight: 305.29.
2'-(O-Propargyl)-guanosine
2'-(O-Propargyl)-guanosine is an indispensable element in the modification of oligonucleotides, enabling the scientific insertion of critical functional groups. This compound further advances as a promising tool within RNA research. Synonyms: 2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; SCHEMBL26509; 2'-(O-Propargyl)-guanosine; 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(prop-2-yn-1-yloxy)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one. Grade: ≥ 98% by HPLC. Molecular formula: C13H15N5O5. Mole weight: 321.29.
2'-(O-Propargyl)-uridine
2'-(O-Propargyl)-uridine is an RNA nucleoside derivative, exhibiting potential applications toward the synthesis of an expansive array of RNA-targeting pharmaceuticals. Its significant usage lies in crafting modified therapeutic oligonucleotides. Synonyms: 2'-o-propargyluridine; 129778-58-1; 2'-O-propargyl-uridine; 2'-(O-Propargyl)-uridine; SCHEMBL3445155. Grade: ≥ 98% by HPLC. Molecular formula: C12H14N2O6. Mole weight: 282.25.
A bis(ethoxyacetic acid) impurity of Cetirizine. Synonyms: Cetirizine N-(2-Ethoxyacetate). Grade: > 95%. Molecular formula: C25H32ClN2O6. Mole weight: 492.00.
2-(p-Chlorophenoxy)-2-methylpropionic acid
Clofibric acid is a PPAR agonist. Uses: Anticholesteremic agents. Synonyms: 2-(4-chlorophenoxy)-2-methylpropanoic acid. Grade: > 98 %. CAS No. 882-09-7. Molecular formula: C10H11ClO3. Mole weight: 214.65.
2-(p-Cyanophenylmethylidenehydrazino)adenosine
2-(p-Cyanophenylmethylidenehydrazino)adenosine is a selective A2A adenosine receptor agonist used for the treatment of Parkinson's disease. It has potential advantages over other A2A agonists because it does not cause dyskinesia, a common and serious side effect of anti-Parkinsonian drugs. Synonyms: 4-[(E)-[[6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]hydrazinylidene]methyl]benzonitrile; 2-(p-Cyanophenylmethylidene-hydrazino)adenosine. Grade: ≥95%. Molecular formula: C18H18N8O4. Mole weight: 410.39.
2-(Pentylsulfanyl)pyrimidine-4,6-diol
2-(Pentylsulfanyl)pyrimidine-4,6-diol is a GRP84 agonist. Synonyms: 4(3H)-Pyrimidinone, 6-hydroxy-2-(pentylthio)-; 4(1H)-Pyrimidinone, 6-hydroxy-2-(pentylthio)-; 6-Hydroxy-2-(pentylthio)-4(3H)-pyrimidinone; 2-(Pentylthio)pyrimidine-4,6-diol; 6-Hydroxy-2-(pentylsulfanyl)-3,4-dihydropyrimidin-4-one. Grade: ≥95%. CAS No. 489403-70-5. Molecular formula: C9H14N2O2S. Mole weight: 214.28.
2-(Phenylmethoxy)-1-propanol β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate can be used as an intermediate in the synthesis of metabolites of propylene glycol, as well as in the synthesis of N-terminal kinase inhibitors with cellular activity. Acts as a solvent for various pharmaceutical compounds. Molecular formula: C23H30O11. Mole weight: 482.48.
2-(Piperidinylmethyl) Hydroxy Donepezil
2-(Piperidinylmethyl) Hydroxy Donepezil is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer's disease. Synonyms: 2,3-Dihydro-2-[hydroxyl-1-phenylmethyl)-4-piperidinyl]methyl]-5,6-dimethoxy-2-(piperidinylmethyl)-1H-inden-1-one. Grade: 98%. CAS No. 1391052-12-2. Molecular formula: C30H40N2O4. Mole weight: 492.65.
(2-Pyridyl) 2,3,4,6-tetra-O-acetyl-1-deoxy-a-D-manno-1-C-pyranoside, a carbohydrate derivative extensively employed in biomedicine investigations for the evaluation of enzymes implicated in carbohydrate metabolism, stands as an indispensable compound. Its utility also extends to the study of glycosyltransferases and glycosidases as well as to the discovery and production of antiviral and anticancer therapeutic agents, making it a significant molecular entity in the field of biochemical research. Mole weight: 409.39.
(2-Pirydyl) 2,3,4,6-tetra-O-acetyl-1-deoxy-b-D-galacto-1-C-pyranoside is an intermediary compound of paramount importance in the vast realm of biomedical research, serving as a ubiquitous piece in the intricate puzzle of antiviral and anticancer drug synthesis. It aids in stopping the proliferation and invasion of pathogenic cells. Mole weight: 409.39.
2-Propenyl O-2,?3,?4,?6-Tetra-O-acetyl-α-D-glucopyranosyl-(1→4)?-O-2,?3,?6-tri-O-acetyl-α-D-glucopyranosyl-(1→4)?-β-D-glucopyranoside Triacetate can be used as an intermediate in the synthesis of 6-α-D-Glucopyranosyl Maltotriose. Sugar composition of sake. Synonyms: β-D-Glucopyranoside, 2-propenyl O-2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl-(1→4)-O-2,3,6-tri-O-acetyl-α-D-glucopyranosyl-(1→4)-, triacetate. CAS No. 142831-55-8. Molecular formula: C41H56O26. Mole weight: 964.87.
(2R)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile
(2R)-1-(2-Chloroacetyl)-2-pyrrolidinecarbonitrile is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 12; Vildagliptin Chloroacetyl Nitrile (R)-Isomer. CAS No. 565452-98-4. Molecular formula: C7H9ClN2O. Mole weight: 172.61.
(2R)-2-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-4-propylidene-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of Lincomycin, which is a lincosamide antibiotic from the actinomycete Streptomyces lincolnensis. Synonyms: tert-butyl (R)-2-(((tert-butyldimethylsilyl)oxy)methyl)-4-propylidenepyrrolidine-1-carboxylate; 2-Methyl-2-propanyl (2R)-2-({[dimethyl(2-methyl-2-propanyl)silyl]oxy}methyl)-4-propylidene-1-pyrrolidinecarboxylate; 1-Pyrrolidinecarboxylic acid, 2-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-4-propylidene-, 1,1-dimethylethyl ester, (2R)-. Molecular formula: C19H37NO3Si. Mole weight: 355.59.
(2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine is an intermediate in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: Intermediate in the preparation of enantiomerically pure aprepitant diastereomers and derivatives. Synonyms: Aprepitant dehydro dealkyl; Desfluro Aprepitant; 2H-1,4-Oxazine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-, (2R)-; (R)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-5-(4-fluorophenyl)-3,6-dihydro-2H-1,4-oxazine; 2alpha-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-5,6-dihydro-2H-1,4-oxazine; Aprepitant Impurity 6. Grade: ≥95%. CAS No. 380499-07-0. Molecular formula: C20H16F7NO2. Mole weight: 435.33.
An impurity of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. CAS No. 2055912-03-1. Molecular formula: C24H32FN5O. Mole weight: 425.5.
An impurity of safinamide, which is a selective monoamine oxidase B inhibitor reducing degradation of dopamine. Synonyms: Safinamide Impurity 4; (R)-N2-{4-[(3-fluorobenzyl)oxy]benzyl}alaninamide. Grade: ≥ 98%. CAS No. 174756-44-6. Molecular formula: C17H19FN2O2. Mole weight: 302.349.
[2R-(2a,3a,4b,5a)]-3,4,5-Trihydroxy-2-piperidinecarboxylic acid methyl ester, a prominent biomedical compound extensively employed as an essential chemical intermediate in the synthesis of pharmaceutical drugs, assumes paramount significance in the realm of medicinal advancements. Its exceptional architectural configuration, coupled with distinctive functional groups, bestows it with the pivotal capacity to orchestrate the creation of potent therapeutic agents tailored to address a wide spectrum of diseases encompassing cardiovascular disorders and neurological afflictions. Synonyms: 2-Piperidinecarboxylic acid, 3,4,5-trihydroxy-, methyl ester, [2R-(2α,3α,4β,5α)]-. CAS No. 116366-70-2. Molecular formula: C7H13NO5. Mole weight: 191.18.
[2R-[2α(S*),3β,5β]]-5-Ethyltetrahydro-3-methyl-α-(methylamino)-2-furanacetic Acid is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 2-Furanacetic acid, 5-ethyltetrahydro-3-methyl-α-(methylamino)-, [2R-[2α(S*),3β,5β]]-. CAS No. 127605-69-0. Molecular formula: C10H19NO3. Mole weight: 201.26.
Pivmecillinam EP Impurity B is an impurity of Pivmecillinam, which is an orally active prodrug of the broad-spectrum penicillin antibiotic Mecillinam. Synonyms: Pivmecillinam Impurity B; [2R-[2α(S*),4β]]-4-[[(2,2-Dimethyl-1-oxopropoxy)methoxy]carbonyl]-α-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-5,5-dimethyl-2-thiazolidineacetic Acid; 2-Thiazolidineacetic acid, 4-[[(2,2-dimethyl-1-oxopropoxy)methoxy]carbonyl]-α-[[(hexahydro-1H-azepin-1-yl)methylene]amino]-5,5-dimethyl-, [2R-[2α(S*),4β]]-. CAS No. 72584-25-9. Molecular formula: C21H35N3O6S. Mole weight: 457.58.
(2'R)-2'-deoxy-2'-fluoro-2'-C-methyluridine
PSI-6206 is a selective HCV RNA polymerase inhibitor. It is the unphosphorylated parent compound of triphosphate analog PSI-7409, which is a potent inhibitor of the HCV NS5B RNA dependent RNA polymerase. Synonyms: RO-2433; RO 2433; RO2433; PSI6206; PSI 6206; PSI-6206; GS331007; GS-331007; GS 331007; 2'-Deoxy-2'-fluoro-2'-C-methyluridine; Sofosbuvir Metabolite GS331007; 1-((2R,3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; (2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine; ZL-01 metabolite M9; 2'-Deoxy-2'-Fluoro-2'-methyluridine. Grade: ≥95%. CAS No. 863329-66-2. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
(2'R)-2'-Deoxy-2'-fluoro-2'-Methyl-uridine 3',5'-dibenzoate, a remarkable therapeutic agent, demonstrates potential in the fight against cancer, prohibiting tumor growth and prompting apoptosis in cancer cells. Synonyms: ((2R,3R,4R,5R)-3-(Benzoyloxy)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-4-methyltetrahydrofuran-2-yl)methyl benzoate; Uridine, 2'-deoxy-2'-fluoro-2'-methyl-, 3',5'-dibenzoate, (2'R)-; [(2R,3R,4R,5R)-3-Benzoyloxy-5-(2,4-dioxopyrimidin-1-yl)-4-fluoro-4-methyl-tetrahydrofuran-2-yl]methyl benzoate; (2R,3R,4R,5R)-2-[(benzoyloxy)methyl]-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-4-methyloxolan-3-yl benzoate. Grade: 98%. CAS No. 863329-65-1. Molecular formula: C24H21FN2O7. Mole weight: 468.43.
(2'R)?-2'-?Deoxy-?2'-?fluoro-?2'-?methyl-uridine 5'-?Triphosphate Triethylammonium Salt
(2'R)?-2'-Deoxy-2'-fluoro-2'-methyl-uridine 5'-Triphosphate Tetrasodium Salt is an impurity of Sofosbuvir. That prodrug could be metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate. Synonyms: Sofosbuvir Impurity; RO 2433 Triphosphate Triethylammonium Salt. Grade: 95%. Molecular formula: C28H61FN5O14P3. Mole weight: 803.73.
(2R)-(2R)-2-(4-Hydroxyphenyl)glycyl-(2R)-2-[(2S,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]glycyl-(2R)-2-(4-hydroxyphenyl)glycyl-2-[(2S,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]-glycine is an intermediate in the synthesis of Amoxicillin, which is an antibiotic used to treat a number of bacterial infections including middle ear infections, strep throat, pneumonia, skin infections, and urinary tract infections. Synonyms: (2S,4S)-2-[(1R)-1-{[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino}-2-{[(1R)-2-({(R)-carboxy[(2S,4S)-4-carboxy-5,5-dimethyl-1,3-thiazolidin-2-yl]methyl}amino)-1-(4-hydroxyphenyl)-2-oxoethyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid; 2-Thiazolidineacetic acid, α-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-2-[(2S,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]acetyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-4-carboxy-5,5-dimethyl-, (αR,2S,4S)-. Grade: 98%. CAS No. 297175-63-4. Molecular formula: C32H40N6O11S2. Mole weight: 748.82.
(2'R,2S,cis)-Saxagliptin
An impurity of Saxagliptin. Saxagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) used as a hypoglycemic drug. It was approved to treat type 2 diabetes. Synonyms: (1S,3S,5S)-2-[(2R)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile. Grade: 95%. CAS No. 1564265-93-5. Molecular formula: C18H25N3O2. Mole weight: 315.417.
(2R,3R,11bR)-Dihydrotetrabenazine D-Val
(2R,3R,11bR)-Dihydrotetrabenazine D-Val is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3R,11bR)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-2-yl D-valinate; D-Valine (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester. CAS No. 1025504-59-9. Molecular formula: C24H38N2O4. Mole weight: 418.57.
(2R,3R,11bS)-Dihydrotetrabenazine
(2R,3R,11bS)-Dihydrotetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: Tetrabenazine Related Impurity 8 (2R,3R,11bS); (2R,3R,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11bhexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol. Grade: 98%. CAS No. 862377-29-5. Molecular formula: C19H29NO3. Mole weight: 319.44.
(2R,3R,11bS)-Dihydrotetrabenazine D-Val
(2R,3R,11bS)-Dihydrotetrabenazine D-Val is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3R,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-2-yl D-valinate; D-Valine (2R,3R,11bS)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester. Molecular formula: C24H38N2O4. Mole weight: 418.57.
(2R,3R,11bS)-Dihydrotetrabenazine L-Val
(2R,3R,11bS)-Dihydrotetrabenazine L-Val is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2R,3R,11bS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-2-yl L-valinate; L-Valine (2R,3R,11bS)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo(a)quinolizin-2-yl ester. Molecular formula: C24H38N2O4. Mole weight: 418.57.
(2R,3R)-2-benzhydryl-N-benzylquinuclidin-3-amine-(D)-10-camphorsulfonate is an impurity of Maropitant. Maropitant is a neurokinin (NK1) receptor antagonist. Synonyms: Maropitant Impurity 1. Grade: 99% by HPLC. CAS No. 2243127-08-2. Molecular formula: C37H46N2O4S. Mole weight: 614.85.
(2R,3R)-3-[(3aR,4R,6aS)-2,2-Diethyltetrahydro-5-(phenylmethyl)-4H-1,3-dioxolo[4,5-c]pyrrol-4-yl]-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2-propanediol, a remarkable and highly promising pharmaceutical compound, stands as a potential breakthrough in the realm of cancer therapeutics. This potent substance exhibits profound anticancer properties, acting on specific molecular pathways intrinsic to tumor growth and progression. Intriguingly, diverse preclinical investigations have unveiled its ability to effectively combat various malignancies, thus warranting extensive research endeavors and clinical trials aimed at deciphering its safety, efficacy, and untapped potential as a pioneering therapeutic agent, heralding a new era in cancer treatment. Molecular formula: C25H43NO5Si. Mole weight: 465.71.
(2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-3a-methyl-6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one is a potent biomedicine used in the treatment of various diseases. Its unique chemical structure allows it to target specific receptors involved in inflammatory responses, making it highly effective against autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. Extensive research has shown promising results in inhibiting the overactivation of immune cells, thereby reducing inflammation associated with these conditions. Synonyms: 2,2'-Anhydro-2'-C-methyl-1-(beta-D-arabinofuranosyl)uracil; (2R,3R,3aS,9aR)-3-hydroxy-2-(hydroxymethyl)-3a-methyl-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one. Molecular formula: C10H12N2O5. Mole weight: 240.22.
(2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-6-imino-3a-methyl-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, commonly known as THHIMP, is a groundbreaking biomedicine widely employed for the eradication of bacterial infections. Its remarkable antimicrobial properties have been substantiated against an extensive spectrum of pathogens, rendering it an indispensable tool in combating the onslaught of diverse ailments triggered by unchecked bacterial proliferation. Synonyms: 2,2'-Anhydro-4-imino-2'-C-methyl-D-arabino-uridine. Molecular formula: C10H13N3O4. Mole weight: 239.23.
(2R,3R,3aS,9aR)-6-Amino-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5][1,3]oxazolo[3,2-a]pyrimidin-3-ol is a potential therapeutic agent. It's commonly used in biomedical research focusing on treatment of neurodegenerative diseases, particularly Alzheimer's, targeting the beta-amyloid peptides that aggregate in the brains of patients. Synonyms: 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 6-amino-2,3,3a,9a-tetrahydro-3-hydroxy-, (2R,3R,3aS,9aR)-; (2R,3R,3aS,9aR)-6-amino-2-(hydroxymethyl)-2,3,3a,9a-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-3-ol. Grade: 95%. CAS No. 782400-39-9. Molecular formula: C9H13N3O4. Mole weight: 227.22.
An impurity of Desoximetasone, which is a synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity. Synonyms: ((2R,3R,4aS,4bS,10aS,10bR,11S,12aS)-10b-fluoro-2,11-dihydroxy-3,10a,12a-trimethyl-1,8-dioxo-1,2,3,4,4a,4b,5,6,8,10a,10b,11,12,12a-tetradecahydrochrysen-2-yl)methyl dihydrogen phosphate; 1,8(2H,4bH)-Chrysenedione, 10b-fluoro-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2,11-dihydroxy-3,10a,12a-trimethyl-2-[(phosphonooxy)methyl]-, (2R,3R,4aS,4bS,10aS,10bR,11S,12aS)-. Molecular formula: C22H30FO8P. Mole weight: 472.44.
(2R,3R,4R)-2-(Hydroxymethyl)-2-methyl-3,4-pyrrolidinediol is a crucial compound in the biomedicine industry. It is extensively used in the synthesis of pharmaceutical drugs employed for the treatment of various diseases. Its versatile properties and chemical structure make it an indispensable component in the development of medications targeting specific ailments. Synonyms: 3,4-Pyrrolidinediol, 2-(hydroxymethyl)-2-methyl-, (2R,3R,4R)-. CAS No. 1262539-33-2. Molecular formula: C6H13NO3. Mole weight: 147.17.
(2R,3R,4R)-3,4-Difluoro-1-(phenylmethyl)-2-pyrrolidinemethanol, a remarkable biomedicine, exhibits exceptional potential in the treatment of diverse ailments. Synonyms: 2-Pyrrolidinemethanol, 3,4-difluoro-1-(phenylmethyl)-, (2R,3R,4R)-. CAS No. 1701465-52-2. Molecular formula: C12H15F2NO. Mole weight: 227.25.
(2R,3R,4R)-3,4-Dihydroxy-2-(hydroxymethyl)-1-pyrrolidinepropanoic acid, also known as (2R,3R,4R)-DHMPA, holds immense importance in the biomedical field. This remarkable compound showcases tremendous potential as a therapeutic agent for an array of ailments. Its profound impact lies in its ability to enhance immune response, curtail viral replication, and alleviate inflammation. As a result, (2R,3R,4R)-DHMPA has emerged as a highly promising contender for the treatment of viral infections, inflammatory disorders, and immune-related maladies. Synonyms: 1-Pyrrolidinepropanoic acid, 3,4-dihydroxy-2-(hydroxymethyl)-, (2R,3R,4R)-; N-(2-carboxyethyl)-1,4-dideoxy-1,4-imino-d-arabinitol. CAS No. 1207674-35-8. Molecular formula: C8H15NO5. Mole weight: 205.21.
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: benzoic acid [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-2-oxolanyl]methyl ester; D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, γ-lactone, 3,5-dibenzoate, (2R)-; (2R)-2-Deoxy-2-fluoro-2-methyl-D-erythro-pentonic acid γ-lactone 3,5-dibenzoate. Grade: ≥95%. CAS No. 874638-80-9. Molecular formula: C20H17FO6. Mole weight: 372.34.
(2R,3R,4R,5R)-2-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxyl methyl)tetrahydrofuran-3,4-diyl diacetate is an impurity of 5-Azacytidine, an antiproliferative/cytotoxic agent for leukemia therapy. Synonyms: (2R,3R,4R,5R)-2-(4-Amino-2-oxo-1,3,5-triazin-1(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diyl diacetate; 1415316-72-1. CAS No. 1415316-72-1. Molecular formula: C12H16N4O7. Mole weight: 328.28.
(2R,3R,4R,5R)-2-{4-amino-7h-pyrrolo[2,3-d]pyrimidin-7-yl}-3-ethenyl-5-(hydroxymethyl)oxolane-3,4-diol is an uniquely antiviral tool. It primarily assists in the fight against HIV infection and its basic action relies on blocking reverse transcriptase, a key enzyme in viral replication. Synonyms: 4-amino-7-(2-c-vinyl-beta-d-ribofuranosyl)-7h-pyrrolo[2,3-d]pyrimidine. CAS No. 443642-57-7. Molecular formula: C13H16N4O4. Mole weight: 292.29.
(2R,3R,4R,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). CAS No. 2271248-78-1. Molecular formula: C21H25ClO6. Mole weight: 408.88.
(2R,3R,4R,5R)-2-((Benzoyloxy)methyl)-5-(4'-chloro-5,5'-diiodo-7H-[4,7'-bipyrrolo[2,3-d]pyrimidin]-7-yl)tetrahydrofuran-3,4-diyl dibenzoate is a synthetic compound with potential anti-cancer efficacy. It mainly interferes with DNA replication and transcription, and is used in studies targeting genetic diseases and cancer. Synonyms: 4'-Chloro-5,5'-diiodo-7-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4,7'-bi-7H-pyrrolo[2,3-d]pyrimidine. Grade: 98%. Molecular formula: C38H25ClI2N6O7. Mole weight: 966.90.
(2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite, an indispensable phosphoramidite reagent, demonstrates immense significance within the realm of biomedicine. Its role primarily revolves around its extensive utilization in synthesizing oligonucleotides for a diverse range of crucial applications. These include the fields of gene therapy, molecular diagnostics, and antisense therapy. CAS No. 1797762-50-6. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07.
(2R,3R,4R,5R)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2,4-dioxo-3,4-Dihydropyrimidine-1(2H)-yl)-4-(methoxy-d3)tetrahydrofuran-3-yl(2-cyanoethyl)diisopropyl phosphoramidite, a synthetic compound, is a crucial reagent in oligonucleotide synthesis, utilized in the biomedical industry. With its demonstrated efficacy in synthesizing RNA and DNA analogs, this compound has enormous potential for therapeutic use in the treatment of various diseases, including HIV, cancers, and inherited genetic disorders. Its role as a molecular building block necessitates nuanced applications in biochemistry and genetics and underscores the importance of continued research and development in molecular synthesis. CAS No. 2387921-91-5. Molecular formula: C40H46D3N4O9P. Mole weight: 763.81.
(2R,3R,4R,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)-1-pyrrolidinepropanoic acid is an organic compound used in biomedicine for the study of metabolic diseases. Its behavior in the human body assists in understanding the pathways and potential drug targets for diabetes. Synonyms: 1-Pyrrolidinepropanoic acid, 3,4-dihydroxy-2,5-bis(hydroxymethyl)-, (2R,3R,4R,5R)-; N-(2-carboxyethyl)-2,5-dideoxy-2,5-imino-d-mannitol. CAS No. 1207674-67-6. Molecular formula: C9H17NO6. Mole weight: 235.24.
(2R,3R,4R,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)-1-pyrrolidinepropanoic acid tert-butyl ester is a biomedical compound used for its potential therapeutic effects. It has shown promise in the treatment of certain diseases, possibly due to its interaction with specific molecular targets. Molecular formula: C13H25NO6. Mole weight: 291.34.
(2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-yl benzoate, a pharmaceutical intermediate of great consequence, serves as a vital component in the synthesis of antiviral drugs. It has proven to be particularly effective in the development of Tenofovir Disoproxil Fumarate, a drug that upholds a significant role in the treatment of people living with HIV/AIDS. Molecular formula: C17H17FN2O6. Mole weight: 364.33.
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-2-[(4-chlorobenzoyloxy)methyl]-4-fluoro-4-methyloxolan-3-yl 4-chlorobenzoate is an exemplarily remarkable medication for treating chronic lymphocytic leukemia and small lymphocytic leukemia. This class of drugs known as nucleoside analogues remarkably functions by interfering with cancer cells' DNA synthesis and leads to their ultimate death. Synonyms: (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(((4-chlorobenzoyl)oxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl 4-chlorobenzoate; 9H-Purin-2-amine, 9-[(2R)-3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-; 9-[(2R)-3,5-Bis-O-(4-chlorobenzoyl)-2-deoxy-2-fluoro-2-methyl-β-D-erythro-pentofuranosyl]-6-chloro-9H-purin-2-amine. Grade: 98%. CAS No. 1294481-82-5. Molecular formula: C25H19Cl3FN5O5. Mole weight: 594.81.
(2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyloxolan-3-ol is an incredibly potent antiviral compound, employed to combat both hepatitis B and HIV infections. Acting through the inhibition of the reverse transcriptase enzyme, it can reduce viral load and limit replication within the patient's bloodstream. Synonyms: 5-(2-Amino-6-chloro-purin-9-yl)-4-fluoro-2-hydroxymethyl-4-methyl-tetrahydro-furan-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-9H-purin-9-yl)-2-(hydroxymethyl)-4-fluoro-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-Amino-6-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyltetrahydrofuran-3-ol; (2R,3R,4R,5R)-5-(2-amino-6-chloro-purin-9-yl)-4-fluoro-2-(hydroxymethyl)-4-methyl-tetrahydrofuran-3-ol. CAS No. 881881-89-6. Molecular formula: C11H13ClFN5O3. Mole weight: 317.70.