BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Amino Adenosine | The purine nucleoside analog; has role in induction of apoptosis in multiple myeloma. Uses: The purine nucleoside analog. Synonyms: 8-Aminoadenosine; 6,8-Diamino-9-β-D-ribofuranosyl-9H-purine; NSC 90394; (2R,3R,4S,5R)-2-(6,8-diamino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Amino-D-adenosine. Grade: ≥95%. CAS No. 3868-33-5. Molecular formula: C10H14N6O4. Mole weight: 282.26. |  |
| 8-Aminoadenosine-5'-triphosphate lithium salt | 8-Aminoadenosine-5'-triphosphate lithium salt is a pivotal biochemical compound characteristically employed in cellular research to investigate the mechanisms elucidating the varied roles of ATP, encompassing signal transduction and energy transfer. Its diverse derivatives, owing to their ability to modulate the activity of an array of ion channels and transporters, display a promising potential in battling afflictions like hypertension, arrhythmia, as well as cancer. Synonyms: 8-Amino-ATP. Molecular formula: C10H17N6O13P3·xLi. Mole weight: 522.20 (free acid). | |
| 8-Aminoguanosine | A potent inhibitor of purine nucleoside phosphorylase. Synonyms: Inosine, 2,8-diamino-; NSC 90390; 2,8-Diaminoinosine; 2,8-diamino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one. Grade: 98%. CAS No. 3868-32-4. Molecular formula: C10H14N6O5. Mole weight: 298.26. | |
| 8-Aminoguanosine-13C2,15N | 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine, which is a potent inhibitor of purine nucleoside phosphorylase. Synonyms: 2,8-Diaminoinosine-13C2,15N. Molecular formula: C8[13C]2H14N5[15N]O5. Mole weight: 301.23. | |
| 8-Amino-Inosine | 8-Amino-Inosine is a derivative of Inosine, a nucleoside that is found in tRNAs and is essential for the proper translation of genetic code in a wobble base pair. Inosine is also known to exert neuroprotective properties and has been used to treat stroke patients to restore neural function. 8-Amino-Inosine have been studied as a potential chemotherapeutic agent for the treatment of leukemia function by the cytodestruction of the neoplastic cells. Synonyms: NSC 109320. Grade: 96%. CAS No. 13389-16-7. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8a-Oxo Avermectin B1a | 8a-Oxo Avermectin B1a is a metabolite of Avermectin B1a that can be used as an insecticide and acaricide on tomatoes and strawberries in permanent greenhouses and walk-in tunnels. Synonyms: 5-O-Demethyl-28-oxo-Avermectin A1a; Ivermectin 8a-oxo-H2B1a. CAS No. 102190-68-1. Molecular formula: C48H70O15. Mole weight: 887.07. | |
| 8a-oxo-eprinomectin B1a | 8a-oxo-eprinomectin B1a is an impurity of eprinomectin, a broad-spectrum endectocide used to control various species and stages of internal and external parasites. Synonyms: N-[(3S,4S,6S)-6-{[(3S,4S,6R)-6-{[(1R,2'R,2R,3'S,5R,6'S,8S,12R,14E,16S,17S,18E,20Z,24S)-2'-[(2S)-but-2-yl]-2,24-dihydroxy-3,3',15,17-tetramethyl-6,22-dioxo-2',3'-dihydrospiro[7,11,23-trioxatetracyclo[19.2.1.18,12.05,24]pentacosa-3,14,18,20-tetraene-10,6'-pyran]-16-yl]oxy}-4-methoxy-2-methyl-3,4,5,6-tetrahydro-2H-pyran-3-yl]oxy}-4-methoxy-2-methyl-3,4,5,6-tetrahydro-2H-pyran-3-yl]acetamide. Molecular formula: C50H73NO15. Mole weight: 928.13. | |
| 8-APT-cGMP | 8-APT-cGMP is an isozyme-selective stimulator of cGMP-dependent protein kinase I a with a prenference for type I a over I by a factor of 200. Synonyms: 8- (2- Aminophenylthio)guanosine- 3', 5'- monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 144509-87-5. Molecular formula: C16H16N6O7PS · Na. Mole weight: 490.4. | |
| 8-Aza-2'-beta-C-methylguanosine | 8-Aza-2'-beta-C-methylguanosine: One compound, with a rather intricate name - 8-Aza-2'-beta-C-methylguanosine, finds significant application in the biomedical sector for research and development. In fact, scientists readily exploit its synthetic forerunner role while manufacturing a range of antiviral medications targeting RNA viruses, an area of paramount importance. Its unmatched constitution and characteristics render it an indispensable asset in the realm of drug exploration and medicinal chemistry, fostering the battle against debilitating viral afflictions. Grade: ≥95%. Molecular formula: C10H14N6O5. Mole weight: 298.26. | |
| 8-Aza-2'-deoxyadenosine | 8-Aza-2'-deoxyadenosine, a potent compound widely employed in the biomedical sector, exhibits immense potential for the treatment of diverse malignancies, notably leukemia and lymphoma. Its efficacy lies in its ability to impede DNA and RNA synthesis, culminating in the robust suppression of tumor proliferation. As a pivotal research asset, this nucleoside analog enables in-depth elucidation of oncogenic mechanisms and facilitates the innovative formulation of therapeutic interventions. Molecular formula: C9H12N6O3. Mole weight: 252.23. | |
| 8-Aza-5'-AMP | 8-Aza-5'-AMP, a nucleoside analog, has been widely employed in exploring the activity of purine nucleoside phosphorylase (PNP) and its role in immune system functionality. Moreover, it maintains immense potential for conducting experiments on T-cell depletion and treating severe ailments like autoimmune diseases and cancer. Synonyms: 8- Azaadenosine- 5'- O- monophosphate. Molecular formula: C9H13N6O7P (free acid). Mole weight: 348.2 (free acid). | |
| 8-Aza-7-deaza-2'-deoxyadenosine (4-Amino-1-(2-deoxyribofuranosyl)pyrazolo[3,4-d]-pyrimidine) | 8-Aza-7-deaza-2'-deoxyadenosine (4-Amino-1-(2-deoxyribofuranosyl)pyrazolo[3,4-d]-pyrimidine), an extensively researched and scientifically proven potent anticancer drug, demonstrates exceptional efficacy in impeding DNA synthesis and growth of cancer cells. This remarkable compound exhibits impressive results in precisely targeting and inhibiting cancer progression, positioning itself as an invaluable asset within the realm of biomedicine. Grade: ≥ 95%. CAS No. 17318-21-7. Molecular formula: C10H13N5O3. Mole weight: 251.24. | |
| 8-Aza-7-deaza-2'-deoxyguanosine | 8-Aza-7-deaza-2'-deoxyguanosine, an indispensable component, significantly contributes to the advancement of antiviral pharmaceuticals aimed at countering ailments engendered by DNA viruses, including herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its paramount function lies in impeding viral duplication through the disruption of viral DNA synthesis. Grade: ≥ 95%. CAS No. 100644-70-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 8-Aza-7-deaza-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite | 8-Aza-7-deaza-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a remarkably efficient phosphoramidite building block employed in solid-phase research and development, facilitating the generation of modified RNA or DNA oligonucleotides. Through its incorporation, 8-aza-7-deaza modifications are introduced. Synonyms: 5'-Dimethoxytrityl-N-dimethylformamidine-8-aza-7-deaza-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 7-Deaza-8-aza-dG-CE Phosphoramidite (PPG). Grade: 95%. CAS No. 500891-26-9. Molecular formula: C43H53N8O7P. Mole weight: 824.91. | |
| 8-Aza-7-deaza-A CEP | 8-Aza-7-deaza-A CEP is a vital compound used in the biomedical industry. With its unique chemical properties, it plays a crucial role in the synthesis of drugs targeting various diseases. This product is extensively utilized in the research and development of pharmaceuticals aimed at treating cancer, viral infections, and neurological disorders. Molecular formula: C53H66N7O8PSi. Mole weight: 988.19. | |
| 8-Aza-7-deaza-A-CE Phosphoramidite | 8-Aza-7-deaza-A-CE Phosphoramidite, a chemical compound utilized for oligonucleotide synthesis, is a powerful tool for modifying nucleic acid structures in pharmaceutical applications and gene regulation studies. Its exceptional utility extends to therapeutic strategies in genetic disorders and cancer treatment development. Synonyms: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-aza-7-deaza-Adenosine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C49H67N8O7PSi. Mole weight: 939.16. | |
| 8-Azaadenine | 8-Azaadenine is a xanthine oxidase (XAO) inhibitor (IC50 = 0.54 μM, Ki = 0.66 μM). Synonyms: 3H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine; 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine; 1H-v-Triazolo[4,5-d]pyrimidine, 7-amino-; 6-Amino-8-azapurine; 7-Amino-1-v-triazolo[d]pyrimidine; 7-Amino-v-triazolo[d]pyrimidine; 8-Aza-6-aminopurine; NSC 32797. Grade: 95%. CAS No. 1123-54-2. Molecular formula: C4H4N6. Mole weight: 136.11. | |
| 8-Azaadenosine | 8-Azaadenosine, an exquisitely potent and remarkably discriminating inhibitor of adenosine kinasean instrumental enzyme governing the intricate regulation of the purine nucleoside reservoirholds undeniable significance in the realm of biomedical exploration. Its application in scientific inquiry is instrumental in disentangling the intricate web of adenosine kinase's involvement in multifarious physiological states, notably encompassing cancer, epilepsy, and inflammation. Synonyms: 7-Amino-3-β-D-ribofuranosyl-v-triazolo[4,5-d]pyrimidine; 3-β-D-Ribofuranosyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7-amine. Grade: ≥ 97%. CAS No. 10299-44-2. Molecular formula: C9H12N6O4. Mole weight: 268.23. | |
| 8-Aza-ATP | 8-Aza-ATP, a powerful and discriminating activator of the P2Y1 receptor, plays a critical role in an array of physiological processes, including platelet aggregation and neuroprotection. Its therapeutic uses have been explored in a litany of conditions, ranging from stroke and traumatic brain injury to glaucoma, and even hold promise for treating cancer via its potent antiproliferative and antitumor qualities. Synonyms: 8-Azaadenosine-5'-Triphosphate. Grade: ≥90% by AX-HPLC. Molecular formula: C9H15N6O13P3. Mole weight: 508.1. | |
| 8-Aza-cAMP | 8-Aza-cAMP is a paramount compound manifesting as a chemical mimic of cyclic adenosine monophosphate (cAMP). This compound exerts preferential impediment upon the aberrant proliferation of neoplastic cells. Synonyms: 8- Azaadenosine- 3', 5'- cyclic monophosphate. CAS No. 67190-31-2. Molecular formula: C9H10N6O6P · Na. Mole weight: 352.2. | |
| 8-Azaguanosine | 8-Azaguanosine is a modified nucleoside where a nitrogen atom replaces the carbon at the eighth position of the guanine base. This alteration can impact base pairing and hydrogen bonding properties. It is used in biochemical and molecular biology research to study nucleic acid interactions, enzyme activity, and the structural effects of nucleobase modifications. Additionally, 8-azaguanosine is investigated for its potential antiviral and anticancer properties due to its ability to interfere with nucleic acid metabolism. Synonyms: Azaguanosine; NSC 46788; NSC 130283; 5-Amino-3,6-dihydro-3-β-D-ribofuranosyl-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 3H-v-Triazolo[4,5-d]pyrimidin-7(6H)-one, 5-amino-3-β-D-ribofuranosyl-; 3H-v-Triazolo[4,5-d]pyrimidin-7-ol, 5-amino-3-β-D-ribofuranosyl-; 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,4-dihydro-3-β-D-ribofuranosyl-; 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 5-amino-3,6-dihydro-3-β-D-ribofuranosyl-. Grade: ≥95%. CAS No. 2133-80-4. Molecular formula: C9H12N6O5. Mole weight: 284.23. | |
| 8-Azahypoxanthine | 8-Azahypoxanthine is an antimalarial agent that inhibits hypoxanthine-guanine-xanthine phosphoribosyl transferase. Synonyms: 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 3,6-dihydro-; 3,6-Dihydro-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 7H-1,2,3-Triazolo[4,5-d]pyrimidin-7-one, 1,4-dihydro-; 7H-v-Triazolo[4,5-d]pyrimidin-7-one, 1,6-dihydro-; 1H,4H,7H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-one; 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-ol; 1H-v-Triazolo[4,5-d]pyrimidin-7-ol; 2,3-Dihydrotriazolo[4,5-d]pyrimidin-7-one; 7-Hydroxy-1,2,3,4,6-pentaazaindene; 7-Hydroxy-v-triazolo[d]pyrimidine; NSC 22709. Grade: ≥95%. CAS No. 2683-90-1. Molecular formula: C4H3N5O. Mole weight: 137.10. | |
| 8-Azanebularine CE-Phosphoramidite | DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite is a chemical compound used in oligonucleotide synthesis. It protects the 5'-hydroxyl group with a DMTr group and stabilizes the ribose sugar with a 2'-O-TBDMS modification. Additionally, it incorporates 8-azanebularine as a modified nucleoside. The 3'-CE phosphoramidite facilitates nucleotide addition during synthesis. This compound allows for the controlled synthesis of oligonucleotides with specific modifications, important for various applications in molecular biology and biotechnology. Synonyms: DMTr-2'-O-TBDMS-8-azanebularine-3'-CE-Phosphoramidite. Grade: ≥95%. CAS No. 771494-03-2. Molecular formula: C45H60N7O7PSi. Mole weight: 870.08. | |
| 8-Azido-2'-deoxyadenosine | 8-Azido-2'-deoxyadenosine is a potent nucleoside analogue extensively for its ability to selectively inhibit DNA enhancement. This versatile compound finding application in the research of various diseases, including cancers and viral infections. Synonyms: (2R,3S,5R)-5-(6-amino-8-azido-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; Adenosine, 8-azido-2'-deoxy-. Grade: ≥95%. CAS No. 131265-35-5. Molecular formula: C10H12N8O3. Mole weight: 292.17. | |
| 8-Azido-adenosine | 8-Azido-adenosine, a highly versatile compound employed extensively in the realm of biomedical research, serves as an invaluable vehicle for investigating intricate nucleotide metabolism and underlying biological processes. Renowned for its prowess as a tool compound, it ensures precise nucleoside labeling, facilitates comprehensive enzymatic studies, and facilitates the unmasking of intricate protein-protein interactions. The azido functional group it harbors empowers researchers to venture into the realm of bioorthogonal chemistry, enabling thorough exploration of diverse drug targets and mechanisms intricately tied to the realm of disease. Synonyms: 8-Azidoadenosine; (2R,3R,4S,5R)-2-(6-amino-8-azido-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Azido Adenosine. Grade: ≥95% by HPLC. CAS No. 4372-67-2. Molecular formula: C10H12N8O4. Mole weight: 308.25. | |
| 8-Azidoadenosine 5'-monophosphate sodium salt | 8-Azidoadenosine 5'-monophosphate sodium salt is a biomedical compound commonly used in drug discovery and development. This product plays a vital role in studying the detailed mechanisms of various diseases, including cancer, viral infections, and neurological disorders. By acting as a precursor to adenosine triphosphate (ATP), it aids in investigating and evaluating potential therapeutic targets and drug candidates for these conditions. CAS No. 60731-47-7. Molecular formula: C10H13N8O7P. Mole weight: 388.23. | |
| 8-Azidoadenosine-5'-Triphosphate | 8-Azidoadenosine-5'-Triphosphate is a crucial tool in compound for studying ATP-dependent processes. With its azido group, it enables selective photo-crosslinking to ATP-binding proteins and subsequent identification. Widely used in drug discovery and proteomics, it aids in investigating ATP-dependent diseases like cancer and neurodegenerative disorders. Uses: Affinity labels. Synonyms: 8-Azido-ATP; 8-Azidoadenosine 5'-(tetrahydrogen triphosphate); 8-Azido ATP; 8-Azidoadenosine 5'-triphosphate; 8-Azidoadenosine triphosphate. Grade: ≥90% by AX-HPLC. CAS No. 53696-59-6. Molecular formula: C10H15N8O13P3. Mole weight: 548.19. | |
| 8-Azidoadenosine 5'-triphosphate tetralithium salt | 8-Azidoadenosine 5'-triphosphate tetralithium salt, a pivotal agent in the field of biomedicine, serves as an indispensable resource for the investigation of kinase activity and phosphorylation occurrences. Through its utilization as a photoaffinity probe, this compound facilitates the identification and characterization of proteins that bind to adenosine triphosphate (ATP). Its remarkably potent nature renders it a valuable asset in the realm of drug discovery and development. Grade: 85%. Molecular formula: C10H15N8O13P3. Mole weight: 548.19. | |
| 8-Azido-ADP | 8-Azido-ADP is a renowned nucleotide analogue, profoundly disrupting a spectrum of enzymes engaged in DNA replication and repair. Synonyms: 8-Azido-adenosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N8O10P2 (free acid). Mole weight: 468.21 (free acid). | |
| 8-Azido-AMP | 8-Azido-AMP is also known as 8-Azidoadenosine monophosphate, facilitating the meticulous examination of intricate protein functionality, intricate protein-protein associations is and intricate enzymatic behavior. Additionally, it profoundly contributes to the elucidation and understanding of complex drug-target relationships and the enlightenment of promising therapeutic candidates targeting a wide spectrum of ailments. Synonyms: 8-Azido-adenosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H13N8O7P (free acid). Mole weight: 388.23 (free acid). | |
| 8-Benzyloxy-2'-deoxyadenosine | 8-Benzyloxy-2'-deoxyadenosine, an exceptionally powerful antiviral agent, finds its application in combating formidable viral adversaries like HIV and hepatitis B. Remarkably, its inhibitory effect on viral replication and consequential hinderance of viral dissemination unveil its therapeutic prowess. This extraordinary compound, when integrated into nucleic acids, induces a perturbation in viral RNA synthesis, culminating in the abatement of viral replication. Synonyms: (2R,3S,5R)-5-(6-Amino-8-(benzyloxy)-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 8-BENZYLOXY-2/'-DEOXYADENOSINE; (2R,3S,5R)-5-(6-amino-8-phenylmethoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol; (2R,3S,5R)-5-[6-amino-8-(benzyloxy)-9H-purin-9-yl]-2-(hydroxymethyl)oxolan-3-ol. Grade: ≥ 97%. CAS No. 142948-07-0. Molecular formula: C17H19N5O4. Mole weight: 357.37. | |
| 8-Benzyloxy-2'-deoxyguanosine | 8-Benzyloxy-2'-deoxyguanosine is a synthetic compound inhibiting the replication of viruses, including Herpes Simplex Virus (HSV). This compound has shown potential in the research of viral infections by specifically targeting the replication process. Synonyms: 2'-Deoxy-8-(phenylmethoxy)guanosine; 8-(benzyloxy)deoxyguanosine; 8-Benzyloxy-2'-deoxy-D-guanosine. Grade: ≥95%. CAS No. 96964-90-8. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine | 8-Benzyloxy-3'-deoxy-3'-fluoroguanosine, a highly significant compound utilized in the field of biomedicine, assumes a pivotal function in combating diverse viral infections and cancers. Its unique mechanism involves the inhibition of specific viruses, thereby showcasing potent antiviral characteristics. Moreover, its exceptional potential as an agent against cancer lies in its capacity to impede the growth and proliferation of malignant cells. Synonyms: 2-amino-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grade: ≥95%. CAS No. 2389988-61-6. Molecular formula: C17H18FN5O5. Mole weight: 391.35. | |
| 8-Benzyloxy-3'-deoxyguanosine | 8-Benzyloxy-3'-deoxyguanosine, an extensively studied biomedicine, stands as a beacon of hope in combating viral infections, especially within the realm of antiviral therapeutics. Notably, this remarkable compound unveils an impressive repertoire, showcasing its potent antiviral prowess against an array of DNA and RNA viruses. Lending credence to its potential for drug development, it boasts a mechanism of action centered around inhibiting viral replication. Synonyms: Guanosine, 3'-deoxy-8-(phenylmethoxy)-; 2-amino-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grade: ≥95%. CAS No. 2389988-57-0. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-Benzyloxy-5-(2-bromoacetyl)-2-(1H)-quinolinone | 8-Benzyloxy-5-(2-bromoacetyl)-2-(1H)-quinolinone is used in the preparation of phenylethanolamine derivatives as β2 adrenoreceptor agonists. Synonyms: 5-(Bromoacetyl)-8-(phenylmethoxy)-2(1H)-quinolinone; 5-(2-Bromo-1-oxoethyl)-8-benzyloxy-2(1H)-quinolinone; 5-Bromoacetyl-8-benzyloxycarbostyril; 8-(Benzyloxy)-5-(bromoacetyl)quinolin-2(1H)-one; 8-Benzyloxy-5-(2-Bromoacetyl)-1H-quinolin-2-one; 8-Benzyloxy-5-bromoacetylcarbostyril. Grade: ≥95%. CAS No. 100331-89-3. Molecular formula: C18H14BrNO3. Mole weight: 372.21. | |
| 8-Benzyloxy-5-((R)-2-bromo-1-hydroxyethyl)-1H-quinolinone | 8-Benzyloxy-5-((R)-2-bromo-1-hydroxyethyl)-1H-quinolinone emerges as an exceptional pharmaceutical compound harnessed for studying designated ailment manifestations like protracted inflammatory. Uses: Used in the preparation of phenylethanolamine derivatives as β2 adrenoreceptor agonists. Synonyms: 5-[(1R)-2-Bromo-1-hydroxyethyl]-8-(phenylmethoxy)-2(1H)-quinolinone; (R)-8-Benzyloxy-5-(2-bromo-1-hydroxyethyl)carbostyril; 5-(2-Bromo-(R)-1-hydroxyethyl)-8-benzyloxy-2(1H)-quinolinone; 8-(Benzyloxy)-5-((1R)-2-bromo-1-hydroxyethyl)quinolin-2(1H)-one. Grade: ≥95%. CAS No. 530084-79-8. Molecular formula: C18H16BrNO3. Mole weight: 374.23. | |
| 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine | 8-Benzyloxy-9-(b-D-xylofuranosyl)guanine, a formidable antiviral compound widely utilized in the biomedical sector, boasts a remarkable repertoire of vital functions. Its exceptional potency enables the efficacious extermination of herpes simplex virus (HSV) and varicella-zoster virus (VZV) infections, cementing its significance in combating viral afflictions. Unraveling its dynamic mechanism of action reveals an intricate disruption of viral DNA replication, debilitating the pernicious proliferation of these malevolent entities. Synonyms: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-phenylmethoxy-1H-purin-6-one. Grade: ≥95%. Molecular formula: C17H19N5O6. Mole weight: 389.36. | |
| 8-Benzyloxyadenosine | 8-Benzyloxyadenosine is a key compound in biomedicine used for its potential therapeutic benefits in treating various diseases. It acts as an adenosine receptor agonist, primarily targeting A1 and A3 receptors. This unique property makes it an essential tool in studying the role of adenosine receptors in conditions such as cardiovascular diseases, cancer, and neurodegenerative disorders. Synonyms: Adenosine, 8-(phenylmethoxy)-; (2R,3R,4S,5R)-2-(6-Amino-8-(benzyloxy)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 131265-29-7. Molecular formula: C17H19N5O5. Mole weight: 373.36. | |
| 8-(Benzyloxy)guanosine | 8-(Benzyloxy)guanosine is a vital bioactive compound exhibiting potential in studying various diseases, such as cancer. With its inhibition abilities, it targets specific cellular pathways. Synonyms: 8-Benzyloxy-Guanosine; 8-(Phenylmethoxy)guanosine; NSC 90391; 8-Benzyloxyguanosine; 2-Amino-8-(benzyloxy)-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 8-(phenylmethoxy)-; Guanosine, 8-(benzyloxy)-. Grade: ≥95%. CAS No. 3868-36-8. Molecular formula: C17H19N5O6. Mole weight: 389.36. | |
| 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine | 8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine is an antiviral compound, holding immense potential in the development of antiviral therapeutics. Synonyms: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-phenylmethoxy-1H-purin-2-yl]-2-methylpropanamide; 8-BENZYLOXY-N2-ISOBUTYRYL-2/'-DEOXYGUANOSINE; 8-(Benzyloxy)-2'-deoxy-N-(2-methylpropanoyl)guanosine; N-(8-(benzyloxy)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grade: ≥ 90%. CAS No. 136859-75-1. Molecular formula: C21H25N5O6. Mole weight: 443.46. | |
| 8-Br-2',3',6'-TAc-Guo | 8-Br-2',3',6'-TAc-Guo is a bioactive compound, used for studying bacterial and viral afflictions by impeding the proliferation of malignant cells. CAS No. 16717-46-0. Molecular formula: C16H18N6O8Br. Mole weight: 488.6. | |
| 8-Br-2'-O-Me-cAMP | 8-Br-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF without affecting protein kinase A. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 612513-13-0. Molecular formula: C11H12BrN5O6P · Na. Mole weight: 444.1. | |
| 8-Br-2'-O-Me-cAMP-AM | 8-Br-2'-O-Me-cAMP-AM is a precursor of 8-Br-2'-O-Me-cAMP, the specific Epac agonist. 8-Br-2'-O-Me-cAMP is released after the metabolism of 8-Br-2'-O-Me-cAMP-AM by esterases. Synonyms: 8- Bromo- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C14H17BrN5O8P. Mole weight: 494.2. | |
| 8-Br-2'-O-Me-cGMP | 8-Br-2'-O-Me-cGMP is an analogue of cGMP that does not activate both protein kinase G and Epac. It is often used as an inactive control versus 8-Br-cGMP. Synonyms: 8- Bromo- 2'- O- methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C11H12BrN5O7P · Na. Mole weight: 460.1. | |
| 8-Br-2'-O-Me-Guo | 8-Br-2'-O-Me-Guo is an exceptional antiviral compound massively employed within the biomedical sector, showcasing Inhibitory efficacy in the research of diverse viral maladies such as influenza and respiratory syncytial virus. Synonyms: 8- Bromo- 2'- O- methylguanosine. CAS No. 847649-49-4. Molecular formula: C11H14N6O6Br. Mole weight: 376.2. | |
| 8-Br-5'-GMP | 8-Br-5'-GMP is an analogue of 5'-GMP used as a starting structure for 8-modified 5'-GMP derivatives. Synonyms: 8- Bromoguanosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 21870-09-7. Molecular formula: C10H13BrN5O8P (free acid). Mole weight: 442.1 (free acid). | |
| 8-Br-cAMP | 8-Br-cAMP, a synthetic cyclic adenosine monophosphate (cAMP) analog, demonstrates versatile potential in medical and biological sciences. From inhibiting platelet aggregation and inducing cellular differentiation, to regulating gene expression and advancing therapeutic research - its applications span across cancer, cardiovascular, and endocrine disorders. Its potential for enhancing cellular signaling and invigorating treatment research sets it apart as a tool for shaping the future of life sciences. Uses: Reprogramming. Synonyms: 8-Br-cAMP; BCAMP; 8-Bromo-cyclic AMP; 8-Bromoadenosine 3',5'-cyclic monophosphate; 8-bromo-cAMP; 8-Bromo-cyclic 3',5'-AMP; 8-Bromoadenosine cyclic 3',5'-phosphate; Cyclic 8-bromoadenosine 3',5'-monophosphate; 8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; 8-Bromoadenosine 3',5'-monophosphate; 8-bromo-3',5'-cyclic AMP; Cyclic AMP, 8-bromo; 5QO1UW05Q5; CHEBI:64211; MFCD00075580; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate); 8-bromoadenosine 3',5'-(hydrogen phosphate); (4AR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide1111. Grade: 0.98. CAS No. 23583-48-4. Molecular formula: C10H11BrN5O6P. Mole weight: 408.1. | |
| 8-Br-cAMP-AM | 8-Br-cAMP-AM is a precursor of the PKA activator 8-Br-cAMP. The polar active analogue is released after metabolism of 8-Br-cAMP-AM by esterases. Synonyms: 8- Bromoadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 190522-24-8. Molecular formula: C13H15BrN5O8P. Mole weight: 480.2. | |
| 8-Br-c-diGMP | 8-Br-c-diGMP is an analogue of c-diGMP, the bacterial second messenger, which can be used for binding studies and precursor for further modifications with spacers or labels. Synonyms: 8- Bromo- cyclic diguanosine monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H23BrN10O14P2 (free acid). Mole weight: 769.3 (free acid). | |
| 8-Br-cGMP | 8-Br-cGMP is a stimulator of cGMP dependent protein kinases I α, I β & type II and cGMP-gated ion channels (cGMP agonist). Compared to cGMP, it has a superior stability. Synonyms: 8- Bromoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 99% by HPLC. CAS No. 51116-01-9. Molecular formula: C10H10BrN5O7P · Na. Mole weight: 446.1. | |
| 8-Br-cGMP-AM | 8-Br-cGMP-AM is a precursor of 8-Br-cGMP, the PKG activator. The polar active analogue is released after the metabolism of 8-Br-cGMP-AM by esterases. Synonyms: 8- Bromoguanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 272445-71-3. Molecular formula: C13H15BrN5O9P. Mole weight: 496.2. | |
| 8-Br-dA-CE Phosphoramidite | 8-Br-dA-CE Phosphoramidite is a valuable compound used in compound for the research and development of DNA and RNA oligonucleotides. It acting as a building block during the solid-phase research and development of modified DNA and RNA strands, enabling the incorporation of the 8-bromodeoxyadenosine (8-Br-dA) nucleoside. These modified nucleotides find applications in various research areas, including drug discovery, genetic engineering is and diagnostics. Synonyms: 5'-Dimethoxytrityl-N6-dimethylaminomethylidene-8-bromo-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grade: 95%. CAS No. 207906-54-5. Molecular formula: C43H52N8O6PBr. Mole weight: 887.81. | |
| 8-Br-dGTP | 8-Br-dGTP is an analogue of dGTP used for receptor mapping studies and a starting structure for 8-modified dGTP derivatives. Synonyms: 8- Bromo- 2'- deoxyguanosine- 5'- O- triphosphate. Grade: ≥ 95% by HPLC. CAS No. 66891-23-4. Molecular formula: C10H15BrN5O13P3 (free acid). Mole weight: 586.1 (free acid). | |
| 8-Bromo-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol | 8-Bromo-11-(1-methylpiperidin-4-yl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is an impurity of Desloratadine, which is a tricyclic H1 inverse agonist used to treat allergies. Synonyms: 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-bromo-6,11-dihydro-11-(1-methyl-4-piperidinyl)-; 8-Bromo-11-(1-methyl-4-piperidinyl)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol. Molecular formula: C20H23BrN2O. Mole weight: 387.31. | |
| 8-Bromo-1,3,7-trimethylxanthine | 8-Bromo-1,3,7-trimethylxanthine is one of Caffeine derivatives. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Synonyms: 7-Methyl-8-bromotheophylline; 8-Bromo-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione-8-bromocaffeine; NSC 11255; 8-Caffeine bromide; 8-Bromocaffeine; 8-Bromo-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione. Grade: 98%. CAS No. 10381-82-5. Molecular formula: C8H9BrN4O2. Mole weight: 273.09. | |
| 8-Bromo-2',3',5'-tri-O-acetyladenosine | 8-Bromo-2',3',5'-tri-O-acetyladenosine is a potent and selective inhibitor to study the role of adenosine receptors in various diseases, such as cancer, cardiovascular disorders and inflammatory conditions. It has the ability to modulate adenosine signaling pathways. Synonyms: 8-Bromo-adenosine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acetyl-8-bromoadenosine; NSC 79212. Grade: 95%. CAS No. 31281-86-4. Molecular formula: C16H18BrN5O7. Mole weight: 472.25. | |
| 8-Bromo-2',3',5'-tri-O-acetylguanosine | 8-Bromo-2',3',5'-tri-O-acetylguanosine is an exquisitely intricate and exceptionally useful biochemical compound, tailored with intrinsic antiviral capabilities. It is revered for its profound potential in dissecting the intricate dynamics of viral RNA-dependent RNA polymerases. Synonyms: 8-Bromo-guanosine 2',3',5'-Triacetate; 2',3',5'-Tri-O-acetyl-8-bromoguanosine; NSC 174056; NSC 79210. Grade: 98%. CAS No. 15717-45-0. Molecular formula: C16H18BrN5O8. Mole weight: 488.25. | |
| 8-Bromo-2',3',5'-tri-O-acetylguanosine-13C2,15N | 8-Bromo-2',3',5'-tri-O-acetylguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N. 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine, which is a potent inhibitor of purine nucleoside phosphorylase. 8-Bromo-2',3',5'-tri-O-acetylguanosine-13C2,15N is also a labelled analog of 8-Bromo-2',3',5'-tri-O-acetylguanosine. Synonyms: 8-Bromo-guanosine 2',3',5'-Triacetate-13C2,15N; 2',3',5'-Tri-O-acetyl-8-bromoguanosine-13C2,15N; NSC 174056-13C2,15N; NSC 79210-13C2,15N. Molecular formula: C14[13C]2H18BrN4[15N]O8. Mole weight: 491.23. | |
| 8-Bromo-2',5'-pAp | 8-Bromo-2',5'-pAp, a nucleotide analog, is widely applied as a substrate in enzymatic assays to explore RNA polymerase and RNA ligase abilities. Its versatility extends to the development of modified RNA molecules that serve as valuable tools in numerous biomedical fields. These applications include gene therapy for malignancies and genetic dysfunctions. Synonyms: (8Br-2',5'-pAp); 8-Bromo-adenosine-2',5'-bisphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14BrN5O10P2 (free acid). Mole weight: 506.10 (free acid). | |
| 8-Bromo-2'-deoxyadenosine | It is a brominated DNA adduct produced by human DNA polymerases. Synonyms: 8-Bromo-9-(2'-deoxyribofuranosyl)adenine; 8-Bromodeoxyadenosine; NSC 79220; (2R,3S,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-Deoxy-8-bromoadenosine. Grade: ≥98% by HPLC. CAS No. 14985-44-5. Molecular formula: C10H12BrN5O3. Mole weight: 330.14. | |
| 8-Bromo-2'-deoxyadenosine-13C2,15N | Isotope labelled 8-Bromo-2'-deoxyadenosine is a brominated DNA adduct generated by human DNA polymerases. Synonyms: 8-Bromo-2'-deoxyadenosine-13C2,15N; 8-Bromo-9-(2'-deoxyribofuranosyl)adenine-13C2,15N; 8-Bromodeoxyadenosine; NSC 79220-13C2,15N. Molecular formula: C8[13C]2H12BrN4[15N]O3. Mole weight: 333.12. | |
| 8-Bromo-2'-deoxyguanosine | 8-Bromo-2'-deoxyguanosine is a fundamental constituent in compound assuming a crucial role in the exploration and development of antivirals. this compound serves as an elemental building block for nucleoside analogues employed in studying an array of ailments such as herpes, hepatitis B and human immunodeficiency virus (HIV). Synonyms: 8-Bromo-2'-deoxy-guanosine; NSC 105830; 2-Amino-8-bromo-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 8-Bromo-2'-dG; 8-Br-2'-dG; 8-Bromodeoxyguanosine; 8-Bromo-2'-deoxy-D-guanosine. Grade: ≥98% by HPLC. CAS No. 13389-03-2. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromo-2'-deoxyguanosine-13C,15N2 | 8-Bromo-2'-deoxyguanosine-13C,15N2. Synonyms: 8-Bromo-2'-deoxy-guanosine-13C,15N2; 8-Bromo-2'-deoxyguanosine-13C,15N2; NSC 105830-13C,15N2. Molecular formula: C9[13C]H12BrN3[15N]2O4. Mole weight: 349.12. | |
| 8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N2-DMF-5'-O-DMT-guanosine 3'-CE phosphoramidite is a cutting-edge synthetic compound based on guanosine, effectively incorporating 8-bromo modification and DMF-5'-O-DMT protection into guanosine residuals while carrying out oligonucleotide research and development. Synonyms: 5'-Dimethoxytrityl-N2-dimethylaminomethylidene-8-bromo-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-Br-dG-CE Phosphoramidite; 8-Bromo-N2-DMF-5'-O-DMT-2'-deoxyguanosine 3'-CE phosphoramidite. CAS No. 198080-37-4. Molecular formula: C43H52N8O7PBr. Mole weight: 903.9. | |
| 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is an imperative compound, serving as an indispensable phosphorylation recompound engendering the amalgamation of oligonucleotides. Its pervasive utilization in the research of pharmacological exploration, primarily within the domain of nucleotide-based therapeutics spanning antisense oligonucleotides and siRNA. Synonyms: 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-D-adenosine 3'-CE phosphoramidite; 8-Bromo-N6-DMF-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite. Molecular formula: C43H52BrN8O6P. Mole weight: 887.82. | |
| 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine | 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine is a key compound used in biomedical research for studying DNA enhancement and repair. It is primarily utilized in the development of antiviral drugs and therapies targeting viral DNA replication as well as in understanding the mechanisms underlying cell signaling pathways involved in cancer progression and autoimmune diseases. Synonyms: 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxy-guanosine; 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-2'-deoxyguanosine. Molecular formula: C22H40BrN5O4Si2. Mole weight: 574.66. | |
| 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine | 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine is an exceptionally influential compound integral to the research of investigating nucleosides, DNA enhancement and the development of antiviral/anticancer drugs. Synonyms: 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxy-guanosine; 8-Bromo-3',5'-Di-O-tert-butyldimethylsilyl-6-O-benzyl-2'-deoxyguanosine. Molecular formula: C29H46BrN5O4Si2. Mole weight: 664.78. | |
| 8-Bromo-3,7-dihydro-7-(2-methoxyethyl)-3-methyl-1H-purine-2,6-dione | 8-Bromo-3,7-dihydro-7-(2-methoxyethyl)-3-methyl-1H-purine-2,6-dione is one of Caffeine metabolites. Caffeine is a CNS stimulant. Alkaloid, purified from plants of Coffea genus, Rubiaceae. Synonyms: 8-bromo-7-(2-methoxyethyl)-3-methyl-1H-purine-2,6(3H,7H)-dione; 8-bromo-3-methyl-7-beta-methoxyethylxanthine; 8-bromo-6-hydroxy-7-(2-methoxyethyl)-3-methyl-3,7-dihydro-2H-purin-2-one. Grade: ≥95%. CAS No. 313470-45-0. Molecular formula: C9H11BrN4O3. Mole weight: 303.11. | |
| 8-Bromo-3,9-dihydro-3-methyl-1H-purine-2,6-dione | 8-Bromo-3,9-dihydro-3-methyl-1H-purine-2,6-dione is an impurity of Linagliptin. Linagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4) that is a medication used to treat type 2 diabetes in conjunction with exercise and diet. Synonyms: Linagliptin Impurity 45; 3-Methyl-8-bromoxanthine; 8-Bromo-3-methyl-3,7-dihydropurine-2,6-dione; 8-Bromo-3-methylxanthine; Linagliptin 8-Bromo Impurity; 8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione. Grade: ≥95%. CAS No. 93703-24-3. Molecular formula: C6H5BrN4O2. Mole weight: 245.04. | |
| 8-Bromo-3'-deoxy-3'-fluoroguanosine | 8-Bromo-3'-deoxy-3'-fluoroguanosine, an intriguing biomedical compound, holds immense potential in the realm of antiviral drug research and development. Its proven efficacy against formidable viruses such as herpes simplex and human immunodeficiency virus (HIV) fuels scientific curiosity. By delving into the enzymatic activities, mechanisms, and inhibition of viral replication, this compound serves as a vital tool driving progress in the field of antiviral therapeutics. Synonyms: 2-amino-8-bromo-9-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one. Grade: ≥95%. CAS No. 847649-50-7. Molecular formula: C10H11BrFN5O4. Mole weight: 364.13. | |
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