BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-CPT-cAMP-AM | 8-CPT-cAMP-AM is a precursor of 8-CPT-cAMP, the PKA activator. 8-CPT-cAMP is released after the metabolism of 8-CPT-cAMP-AM by esterases. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 663941-66-0. Molecular formula: C19H19ClN5O8PS. Mole weight: 543.9. |  |
| 8-Cyclopentyl-1,3-dimethylxanthine | 8-Cyclopentyl-1,3-dimethylxanthine is a selective and high affinity adenosine A1 receptor antagonist. Its pKi value is 7.5-8. Synonyms: 8-Cyclopentyl-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione; CPT; 8-Cyclopentyltheophylline. Grade: ≥99% by HPLC. CAS No. 35873-49-5. Molecular formula: C12H16N4O2. Mole weight: 248.28. | |
| 8-cyclopentyl-5-methyl-2,6-bis((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-5-methyl-2,6-bis[[5-(1-piperazinyl)-2-pyridinyl]amino]; Palbociclib Impurity G. CAS No. 2458234-37-0. Molecular formula: C31H39N11O. Mole weight: 581.73. | |
| 8-Dechloro-10-chloro Desloratadine | 8-Dechloro-10-chloro Desloratadine is one of Loratadine metabolites. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 10-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 10-chloro-6,11-dihydro-11-(4-piperidinylidene)-; 10-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity 3. Grade: 98%. CAS No. 1346600-61-0. Molecular formula: C19H19ClN2. Mole weight: 310.82. | |
| 8-Dechloro-10-chloro Loratadine | 8-Dechloro-10-chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(10-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(10-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate. Grade: > 98%. CAS No. 1346605-16-0. Molecular formula: C22H23ClN2O2. Mole weight: 382.88. | |
| 8-Dechloro-7-chloro Desloratadine | 8-Dechloro-7-chloro Desloratadine is one of Loratadine metabolites. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 7-chloro-6,11-dihydro-11-(4-piperidinylidene)-; 7-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity 1; 7-Chloro-11-(4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine. Grade: 98%. CAS No. 1346601-53-3. Molecular formula: C19H19ClN2. Mole weight: 310.82. | |
| 8-Dechloro-7-chloro Loratadine | 8-Dechloro-7-chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 4-(7-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(7-Chloro-5,6-dihydro-11H-benzo[5,6] cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate. Grade: > 98%. CAS No. 1346602-19-4. Molecular formula: C22H23ClN2O2. Mole weight: 382.88. | |
| 8-Dechloro-7-chloro-N-methyl Desloratadine | 8-Dechloro-7-chloro-N-methyl Desloratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 7-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; Desloratadine Impurity 4. Grade: 98%. CAS No. 1346600-30-3. Molecular formula: C20H21ClN2. Mole weight: 324.85. | |
| 8-Dechloro-9-chloro Loratadine | 8-Dechloro-9-chloro Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Loratadine (l469575) impurity. Synonyms: 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate. Grade: > 98%. CAS No. 109537-11-3. Molecular formula: C22H23ClN2O2. Mole weight: 382.88. | |
| 8-Demethoxy-8-fluoro Gatifloxacin | 8-Demethoxy-8-fluoro Gatifloxacin is a fluoroquinolone used in the synthesis of Gatifloxacin. Synonyms: 1-cyclopropyl-6,8-difluoro-7-(3-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-cyclopropyl-6,8-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-3-Quinolinecarboxylic acid; AMQ 2; CP 105532; 3-Quinolinecarboxylicacid, 1-cyclopropyl-6. Grade: > 95%. CAS No. 103460-89-5. Molecular formula: C18H19F2N3O3. Mole weight: 363.37. | |
| 8-Desacetyl-8-carboxy daunorubicin hydrochloride | 8-Desacetyl-8-carboxy Daunorubicin Hydrochloride is an impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Uses: Doxorubicin analog. antitumor drug. Synonyms: Doxorubicin Impurity 5; (2S-cis)-4-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid hydrochloride (1:1); NSC 235816; (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-2-tetracenecarboxylic acid hydrochloride (1:1). Grade: ≥95%. CAS No. 58199-96-5. Molecular formula: C26H28ClNO11. Mole weight: 565.96. | |
| 8-Desacetyl-8-carboxy Daunorubicin Hydrochloride Hydrate | 8-Desacetyl-8-carboxy Daunorubicin Hydrochloride Hydrate is an analog of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic acid hydrochloride hydrate; NSC 235816 Hydrate; 2-Naphthacenecarboxylic acid, 3,6-trideoxy-α-L-Lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-, (2S-cis)-, hydrochloride, Hydrate (1:1:x). Grade: ≥95%. Molecular formula: C26H27NO11.HCl.xH2O. Mole weight: 565.96 (anhydrous). | |
| 8-Deschloro-8-bromo Loratadine | 8-Deschloro-8-bromo Loratadine is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Grade: 98%. CAS No. 130642-60-3. Molecular formula: C22H23BrN2O2. Mole weight: 427.33. | |
| 8-Deschloro-8-bromo-N-methyl Desloratadine | 8-Deschloro-8-bromo-N-methyl Desloratadine is one of Loratadine derivatives. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Bromo-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 8-Bromo-11-(1-methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 8-bromo-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-; Desloratadine Impurity 18. Grade: ≥95%. CAS No. 130642-57-8. Molecular formula: C20H21BrN2. Mole weight: 369.30. | |
| 8-[DY-547]-AET-2'-O-Me-cAMP | 8-[DY-547]-AET-2'-O-Me-cAMP is a fluorescent activator (λexc557 nm, λem574 nm) of the exchange protein activated by cAMP (Epac) or cAMP-GEF. Synonyms: 8-(2-[DY-547]-aminoethylthio)-2'-O-methyladenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C43H51N8Na2O13PS3. Mole weight: 1061.1. | |
| 8-[DY-547]-AET-cAMP | 8-[DY-547]-AET-cAMP is a fluorescent cAMP analogue (λexc 557 nm, λem 574 nm). It can be used for research focussed on activation studies of HCN2 channels and other cAMP-responsive binding proteins detailed technical information available. Synonyms: 8-(2-[DY-547]-aminoethylthio)adenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C42H49N8Na2O13PS3. Mole weight: 1047.1. | |
| 8-[DY-547]-AET-cGMP | 8-[DY-547]-AET-cGMP is a fluorescent cGMP analogue (λexc557 nm, λem574 nm). It can be used for kinetic studies of CNG ion channels and other cGMP-reponsive binding proteins. Synonyms: 8-(2-[DY-547]-aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C42H49N8Na2O14PS3. Mole weight: 1063. | |
| 8-[DY-647]-AET-cGMP | 8-[DY-647]-AET-cGMP is a fluorescent cGMP analogue (λexc649 nm, λem666 nm). It can be used for kinetic studies of CNG ion channels and other cGMP-reponsive binding proteins. Synonyms: 8-(2-[DY-647]-aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C44H51N8Na2O14PS3. Mole weight: 1089.1. | |
| 8-epi-10-Deacety Baccatin III | An impurity of Baccatin III which is a precursor to the anti-cancer drug paclitaxel (Taxol). Synonyms: 92999-93-4; 8-epi-10-Deacetylbaccatin III7,11-Methano-5H-cyclodeca(3,4)benz(1,2-b)oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR-(2aalpha,4beta,4aalpha,6beta,9alpha,11alpha,12alpha,12aalpha,12balpha))-. Grade: > 95%. CAS No. 92999-93-4. Molecular formula: C29H36O10. Mole weight: 544.6. | |
| 8-Epi-11,12-epoxy Erythromycin A | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: 8-Epi-11,12-epoxy Erythromycin A. Grade: > 95%. Molecular formula: C37H65NO12. Mole weight: 715.93. | |
| 8-epi Limaprost | an impurity of Limaprost. Grade: > 95%. Molecular formula: C22H36O5. Mole weight: 380.53. | |
| 8-epi-Misoprostol | 8-epi-Misoprostol is an intricate synthetic analog of prostaglandin E1, finding pivotal application in the research of gastric ulcers. Grade: > 95%. Molecular formula: C22H38O5. Mole weight: 382.55. | |
| 8-epi-Prostaglandin F2α | A metabolite of PGF2α. Prostaglandin F2α is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. Uses: Vasoconstrictor agents. Synonyms: (5Z,8β,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic Acid; 7-[3,5-Dihydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl]-5-Heptenoic Acid; 15(S)-8-Iso-PGF2α; 15-F2t-IsoP; 15-F2t-Isoprostane; 8-Isoprostaglandin F2α; 8-epi-PGF2α; 8-iso-Prostaglandin F2α; Isoprostaglandin F2α type-III; 8-Iso-PGF2α. Grade: > 95%. CAS No. 27415-26-5. Molecular formula: C20H34O5. Mole weight: 354.49. | |
| 8-Ethoxycarbonylheptyl N,N-di-O-acetyl-b-chitobioside | 8-Ethoxycarbonylheptyl N,N-di-O-acetyl-β-chitobioside is a pivotal compound extensively utilized in the biomedical sector, garners attention due to its multifaceted applications. Owing to its distinctive composition, it exhibits a remarkable capability to selectively target distinctive pathological routes, thus presenting an optimistic avenue for studying afflictions like rheumatoid arthritis asthma and chronic obstructive pulmonary disease (COPD). Molecular formula: C26H46N2O13. Mole weight: 594.65. | |
| 8-Ethoxycarbonylheptyl N,N'-di-O-acetyl-b-chitobioside | 8-Ethoxycarbonylheptyl N,N'-di-O-acetyl-b-chitobioside is an extraordinary compound specimen with the ability to selectively impact pivotal enzymes and receptors implicated in the pathogenesis of manifold malignancies, encompassing those of the mammary gland, pulmonary region and prostatic milieu. Molecular formula: C26H46N2O13. Mole weight: 594.65. | |
| 8-Ethoxycarbonyloctanoyl-2',3',4',6-tetra-O-acetyl-β-D-galactopyranoside | 8-Ethoxycarbonyloctanoyl-2',3',4',6-tetra-O-acetyl-β-D-galactopyranoside is a compound useful in organic synthesis. Molecular formula: C24H38O12. Mole weight: 518.55. | |
| 8-Ethoxycarbonyloctyl N,N'-Diacetyl-β-chitobioside | A synthetic antigen which may be linked to proteins. Synonyms: 8-(((2R,3R,4R,5S,6R)-3-Acetamido-5-(((2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octyl propionate. Molecular formula: C27H48N2O13. Mole weight: 608.69. | |
| 8-Ethoxy Moxifloxacin HCl | An impurity of Moxifloxacin, which is fourth generation antibacterial agent. Synonyms: Moxifloxacin EP Impurity C; 1-Cyclopropyl-8-ethoxy-6-fluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Hydrochloride. Grade: > 95%. Molecular formula: C22H26FN3O4. HCl. Mole weight: 451.92. | |
| 8-Ethyl Daunorubicin | An impurity of Daunorubicin, which is an anthracycline antibiotic used in the treatment of acute myeloid and lymphocytic leukemia, with adverse reactions such as cardiotoxicity and bone marrow suppression. Synonyms: Daunorubicin Impurity F; 14-Methyldaunorubicin; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-1-methoxy-8-propanoyl-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunorubicin EP Impurity F; Daunorubicin hydrochloride EP Impurity F; NSC 279509; Ethyl Daunorubicin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-8-(1-oxopropyl)-, (8S-cis)-; 8-Ethyldaunorubicin. Grade: >95%. CAS No. 771423-67-7. Molecular formula: C28H31NO10. Mole weight: 541.55. | |
| 8-[Fluo]-AHT-PET-cGMP | 8-[Fluo]-AHT-PET-cGMP is a fluorescent cGMP analogue (λexc494 nm, λem517 nm), which can be used for receptor studies. It has the potential to be a CNG channel inhibitor. Synonyms: 8-(6-[Fluoresceinyl]aminohexylthio)-β-phenyl-1,N2-ethenoguanosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C45H39N7NaO12PS2. Mole weight: 987.9. | |
| 8-[Fluo]-cAMP | 8-[Fluo]-cAMP is a fluorescent cAMP analogue (λexc494 nm, λem517 nm). Synonyms: 8-(2-[Fluoresceinyl]aminoethylthio)adenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 293296-57-8. Molecular formula: C33H27N7NaO11PS2. Mole weight: 815.7. | |
| 8-[Fluo]-cGMP | 8-[Fluo]-cGMP is a fluorescent cGMP analogue (λexc494 nm, λem517 nm). Synonyms: 8-(2-[Fluoresceinyl]aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C33H27N7NaO12PS2. Mole weight: 831.7. | |
| 8-Fluoro-2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine-7-carbonitrile | 8-Fluoro-2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine-7-carbonitrile is an impurity of Varenicline, which is a nicotinic receptor partial agonist used to treat cigarette addiction. Synonyms: 8-Fluoro-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepine-7-carbonitrile; 5-Fluoro-10-azatricyclo[6.3.1.02,7]dodeca-2,4,6-triene-4-carbonitrile; 1,5-Methano-1H-3-benzazepine-7-carbonitrile, 8-fluoro-2,3,4,5-tetrahydro-. CAS No. 328056-66-2. Molecular formula: C12H11FN2. Mole weight: 202.23. | |
| 8-Fluoroadenosine | 8-Fluoroadenosine is an extraordinary compound, acting as a highly selective inhibitor of S-adenosylhomocysteine hydrolase (SAHH) within the dynamic realm of cellular biochemistry. Synonyms: 8-fluoro-adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS No. 23205-67-6. Molecular formula: C10H12FN5O4. Mole weight: 285.23. | |
| 8-Gingerdione | 8-Gingerdione is a remarkable compound exhibiting immense potential in the research of arthritis, cardiovascular diseases and cancer. Renowned for its exceptional anti-inflammatory and antioxidant attributes, it proves advantageous in studying various conditions. Synonyms: (8)-Gingerdione; 8-Gingerdione; [8]-Gingerdione; 77334-06-6; UNII-70E1Y63Q2L; 70E1Y63Q2L; 3,5-Dodecanedione, 1-(4-hydroxy-3-methoxyphenyl)-; 1-(4-Hydroxy-3-methoxyphenyl)dodecane-3,5-dione; 4-Dodecen-3-one, 5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-, (4Z)-; CHEBI:175095; QDSRAFNZQKMHPZ-UHFFFAOYSA-N; DTXSID801316888; 3-(octadecylcarbamoyl)-2-sulfo-propanoic Acid; 8-GINGERDIONE: N=6 (CONSTITUENT OF GINGER); Q27265857; 1-(4-Hydroxy-3-methoxyphenyl)-3,5-dodecanedione, 9CI; 8-GINGERDIONE : N=6 (CONSTITUENT OF GINGER) [DSC]; 1339934-25-6. Grade: > 95%. CAS No. 77334-06-6. Molecular formula: C19H28O4. Mole weight: 320.43. | |
| 8-HA-cAMP | 8-HA-cAMP is a selective analogue of cAMP preferring site B of PKA I. It has high membrane permeability and superior stability towards phosphodiesterases. Synonyms: 8- Hexylaminoadenosine- 3', 5'- monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 59212-44-1. Molecular formula: C16H24N6O6P · Na. Mole weight: 450.4. | |
| 8-Hydrazinoadenosine | 8-Hydrazinoadenosine is a key compound utilized in the field of biomedicine. With its potent properties, it plays a crucial role in the development of drugs targeting various diseases. Its applications include therapies for cancer, as well as neurological and cardiovascular disorders. Synonyms: Adenosine, 8-hydrazinyl-; 8-hydrazino-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-hydrazineyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 3868-34-6. Molecular formula: C10H15N7O4. Mole weight: 297.27. | |
| 8-Hydroxy-2'-Deoxy-Guanosine-13C,15N3 | 8-Hydroxy-2'-Deoxy-Guanosine-13C,15N3 is a labelled analogue of Guanosine. Guanosine is a nucleoside component of nucleotide, which is the primary unit of DNA and RNA. Grade: > 95%. Molecular formula: C9[13C]H13N2[15N]3O5. Mole weight: 287.21. | |
| 8-Hydroxy-3'-deoxy-3'-fluoroguanosine | 8-Hydroxy-3'-deoxy-3'-fluoroguanosine is a profoundly potent antiviral compound widely applied in the biomedical domain, exbiting formidable inhibitory attributes in research of viral infections, encompassing influenza and herpes. Its intrinsic mechanism revolves around perturbing viral replication processes. Grade: ≥95%. Molecular formula: C10H12FN5O5. Mole weight: 301.23. | |
| 8-Hydroxy-3'-deoxyguanosine | 8-Hydroxy-3'-deoxyguanosine, a vital biomarker in the field of biomedicine, assumes a pivotal role in the investigation of oxidative DNA damage. Renowned for its applicability in assessing and diagnosing ailments associated with oxidative stress, including cancer, cardiovascular diseases, neurodegenerative disorders, and aging, this product proves invaluable. Grade: ≥95%. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-Hydroxy-5-nitroquinoline | Nitroxoline is a urinary antibacterial agent had proven to be very effective at combating biofilm infections. Uses: An antibiotic. Synonyms: 5-nitroquinolin-8-ol. Grade: ≥ 95 %. CAS No. 4008-48-4. Molecular formula: C9H6N2O3. Mole weight: 190.16. | |
| 8-Hydroxycarvedilol | 8-Hydroxy Carvedilol is a metabolite of Carvedilol found in humans, rats, dogs and mice. 8-Hydroxy Carvedilol is a β androneceptor antagonist with antioxidant and free radical scavenger activity. Synonyms: 5-[2-Hydroxy-3-[[2-(2-methoxyphenoxy)ethyl]amino]propoxy]-9H-carbazol-1-ol; BM 910162. Grade: > 95%. CAS No. 159426-95-6. Molecular formula: C24H26N2O5. Mole weight: 422.49. | |
| 8-Hydroxy Chlorpromazine | A metabolite of Chlorpromazine. Chlorpromazine is an antipsychotic medication. It can be used to treat psychotic disorders such as schizophrenia. Synonyms: 8-Chloro-10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-ol. Grade: > 95%. CAS No. 3926-67-8. Molecular formula: C17H19ClN2OS. Mole weight: 334.87. | |
| 8-Hydroxy Coumarin | 8-Hydroxy Coumarin is a metabolite of Coumarin. Synonyms: 8-hydroxy-2H-chromen-2-one. Grade: > 95%. CAS No. 2442-31-1. Molecular formula: C9H6O3. Mole weight: 162.14. | |
| 8-Hydroxydeoxyguanosine 5'-monophosphate sodium salt | 8-Hydroxydeoxyguanosine 5'-monophosphate sodium salt is an indispensable resource, playing a pivotal role in probing intricate oxidative DNA impairment and mending mechanisms. It finds extensive utility in uncovering the ramifications inflicted by reactive oxygen species on afflictions like cancer and neurodegenerative ailments. Synonyms: 5'-Guanylic acid, 2'-deoxy-7,8-dihydro-8-oxo-, sodium salt (1:2). CAS No. 1679384-24-7. Molecular formula: C10H14N5O8P.2Na. Mole weight: 409.2. | |
| 8'-Hydroxy-Dihydro Ergocristine | An impurity of 2-Bromo α-Ergocryptine Mesylate. Synonyms: (5'α,8'RS,10α)-9,10-Dihydro-8',12'-dihydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione. Grade: > 95%. Molecular formula: C35H41N5O6. Mole weight: 627.75. | |
| 8-Hydroxy-DPAT hydrobromide | 8-Hydroxy-DPAT hydrobromide is a selective 5-HT1A agonist with moderate affinity for 5-HT7 receptors (pKi = 6.6 at the human 5-HT7 receptor expressed in HEK 293 cells). Synonyms: (±)-8-Hydroxy-2-dipropylaminotetralin hydrobromide. Grade: ≥98% by HPLC. CAS No. 76135-31-4. Molecular formula: C16H25NO.HBr. Mole weight: 328.29. | |
| 8-Hydroxy Efavirenz | 8-Hydroxy Efavirenz is a metabolite of Efavirenz. Synonyms: (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz. Grade: > 95%. CAS No. 205754-33-2. Molecular formula: C14H9ClF3NO3. Mole weight: 331.67. | |
| 8-Hydroxy Entecavir | A derivative of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Synonyms: Entecavir EP Impurity C; 2-amino-9-((1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3H-purine-6,8(7H,9H)-dione. Grade: > 95%. CAS No. 2204369-23-1. Molecular formula: C12H15N5O4. Mole weight: 293.28. | |
| 8-Hydroxyguanine | A crucial nucleotide derivative, 8-Hydroxyguanine, reigns supreme in the biomedical industry for its multifaceted functions. Serving as a DNA damage biomarker for several human diseases, including cancer, it plays a significant role in furthering our understanding of complicated cellular mechanisms. Moreover, its use in research facilitates the evaluation of the efficacy of certain chemotherapy drugs, greatly assisting the development of effective cancer treatments. A product of immense importance, 8-Hydroxyguanine is the key to unlocking the mysteries of DNA repair mechanisms and expanding the frontiers of medical science. Uses: An 8-oxo-guanine repair pathway coordinated by mutyh glycosylase and dna polymerase λ. Synonyms: 2-Amino-6,8-purinediol; 8-Oxo-7,8-dihydroguanine; NSC 22720; 2-Amino-6,8-dihydroxypurine; 7,8-dihydro-8-oxoguanine; 2-Aminopurine-6,8-diol; 2-amino-7,9-dihydro-3H-purine-6,8-dione. Grade: ≥95% by HPLC. CAS No. 5614-64-2. Molecular formula: C5H5N5O2. Mole weight: 167.13. | |
| 8-Hydroxyguanine Hydrochloride | 8-Hydroxyguanine Hydrochloride is a remarkable biomedical compound, standing valiantly as the vanguard against oxidative turmoil inflicted upon our precious DNA by malevolent reactive oxygen species. It unveils the intricacies of oxidative stress-induced DNA harm while appraising the prowess of antioxidant interventions with utmost precision. Synonyms: 2-Amino-6,8-dihydroxypurine Hydrochloride; 2-Amino-7H-purine-6,8-diol hydrochloride; 8-Oxoguanine Hydrochloride. CAS No. 1246818-54-1. Molecular formula: C5H6ClN5O2. Mole weight: 203.59. | |
| 8-Hydroxyguanosine | It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells. It is also an RNA adduct. Uses: Adjuvants, immunologic. Synonyms: 2-Amino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione; 8-OHG; 8-Oxo-7,8-dihydroguanosine; 8-Oxoguanosine; NSC 90393; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-hydroxy-1H-purin-6(9H)-one; 7,8-dihydro-8-oxoguanosine. Grade: ≥97%. CAS No. 3868-31-3. Molecular formula: C10H13N5O6. Mole weight: 299.24. | |
| 8-Hydroxy Guanosine 5'-Triphosphate Triethylammonium Salt | 8-Hydroxy Guanosine 5'-Triphosphate is an oxidized ribonucleotide cDNA induced mutations, suggesting disturbance of genetic information during transcription and/or reverse transcription. It is a potential antiviral drug that causes mutations in genomic RNA. Synonyms: 7,8-Dihydro-8-oxoguanosine 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 2-Amino-9-β-D-ribofuranosylpurine-6,8(1H,9H)-dione 5'-(Tetrahydrogen Triphosphate) Triethylammonium Salt; 8-Ketoguanosine 5'-Triphosphate Bis(triethylammonium) Triethylammonium Salt; 8-OH-GTP Di-TEA Triethylammonium Salt. Grade: 95%. Molecular formula: C10H16N5O15P3 xNEt3. Mole weight: 539.18. | |
| 8-Hydroxy Loxapine | 8-Hydroxy Loxapine is the inactive metabolite of Loxapine. Synonyms: 2-Chloro-11-(4-methyl-1-piperazinyl)dibenz[b,f][1,4]oxazepin-8-ol. Grade: > 95%. CAS No. 61443-77-4. Molecular formula: C18H18ClN3O2. Mole weight: 343.81. | |
| 8-Hydroxy Loxapine-[d8] | 8-Hydroxy Loxapine-[d8] is a labelled impurity of Loxapine. Loxapine is a typical antipsychotic of the dibenzoxazepine class. Synonyms: 8-Hydroxy Loxapine-d8; 2-chloro-11-(4-methylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)dibenzo[b,f][1,4]oxazepin-8-ol. Grade: > 95%. Molecular formula: C18H10ClN3O2D8. Mole weight: 351.86. | |
| 8-Hydroxy-loxapine-glucuronide | 8-Hydroxy-loxapine-glucuronide is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: (2S,3S,4S,5R,6S)-6-((2-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]oxazepin-8-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grade: > 95%. Molecular formula: C24H26ClN3O8. Mole weight: 519.93. | |
| 8-Hydroxy Loxapine N-Oxide | 8-Hydroxy Loxapine N-Oxide is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Synonyms: 2-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-8-ol; 2-Chloro-11-(4-methyl-1-piperazinyl)-dibenz[b,f][1,4]oxazepin-8-ol N-Oxide. Grade: > 95%. Molecular formula: C18H18ClN3O3. Mole weight: 359.81. | |
| 8-Hydroxy-loxapine-sulfate Sodium Salt | 8-Hydroxy-loxapine-sulfate Sodium Salt is a metabolite of Loxapine, a dibenzoxazepine antipsychotic agent. Grade: > 95%. Molecular formula: C18H17ClN3O5SNa. Mole weight: 445.85. | |
| 8-Hydroxymethylguanosine | 8-Hydroxymethylguanosine is a potent biomedical compound, exhibiting immense promise in studying neurodegenerative adversaries such as the notorious Alzheimer's and Parkinson's diseases. Synonyms: Guanosine, 8-(hydroxymethyl)-. Grade: ≥95%. CAS No. 54898-41-8. Molecular formula: C11H15N5O6. Mole weight: 313.27. | |
| 8-Hydroxy Mianserin | 8-Hydroxy Mianserin is a metabolite of Mianserin. Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepin-8-ol; 8-Hydroxymianserin. Grade: > 95%. CAS No. 57257-81-5. Molecular formula: C18H20N2O. Mole weight: 280.36. | |
| 8-Hydroxymianserin b-D-glucuronide | 8-Hydroxymianserin b-D-glucuronide, an imperative and indispensable constituent utilized in the domain of biomedicine, holds immense significance. This compound serves as an invaluable resource to delve into and comprehend the intricate nuances of Mianserin's pharmacokinetic properties. By shedding light on its metabolism and plausible therapeutic advantages, it enables a comprehensive exploration of Mianserin's potential in ameliorating diverse ailments like depression and insomnia. CAS No. 140695-49-4. Molecular formula: C24H28N2O7. Mole weight: 456.50. | |
| 8-Hydroxy mirtazapine | 8-Hydroxy Mirtazapine is the main metabolite of Mirtazapine. Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-8-ol; 8-Hydroxy-6-azamianserin. Grade: > 95%. CAS No. 102335-57-9. Molecular formula: C17H19N3O. Mole weight: 281.35. | |
| 8-Hydroxymirtazapine b-D-glucuronide | 8-Hydroxymirtazapine b-D-glucuronide, a significant compound utilized in the biomedical sector, serves as a potent metabolite of mirtazapine, a frequently prescribed antidepressant. Within this glucuronide derivative, an augmentation of pharmacological activity is observed, rendering it an ideal instrument for investigating the metabolism and remedial impacts of mirtazapine in the treatment of mood disorders and associated ailments. Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepin-8-yl β-D-glucopyranosiduronic acid. CAS No. 155239-47-7. Molecular formula: C23H27N3O7. Mole weight: 457.49. | |
| 8-Hydroxy mirtazapine-d4 | 8-Hydroxy mirtazapine-d4 is a labelled 8-Hydroxy mirtazapine. Mirtazapine HCl is a medication used for the treatment of depression. It can improve mood via restoring the balance of neurotransmitters in the CNS. Grade: > 95%. Molecular formula: C17H15D4N3O. Mole weight: 285.38. | |
| 8-Hydroxy Naltrexone | 8-Hydroxy Naltrexone is a derivative of Naltrexone, which is used to treat alcohol dependence and prevent relapse of opioid dependence. Synonyms: (4R,4aS,5S,7aR,12bS)-3-(cyclopropylmethyl)-4a,5,9-trihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one; (5α,8β)-17-(Cyclopropylmethyl)-3,8,14-trihydroxy-4,5-epoxymorphinan-6-one; Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,8,14-trihydroxy-, (5α,8β)-; (5α,8β)-17-(Cyclopropylmethyl)-4,5-epoxy-3,8,14-trihydroxy-morphinan-6-one. Grade: ≥95%. CAS No. 2139257-33-1. Molecular formula: C20H23NO5. Mole weight: 357.40. | |
| 8-Hydroxy Ondansetron | An impurity of Ondansetron, which is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. Synonyms: 1,2,3,9-Tetrahydro-8-hydroxy-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one. Grade: > 95%. CAS No. 126671-71-4. Molecular formula: C18H19N3O2. Mole weight: 309.36. | |
| 8-Hydroxy-PIPAT | 8-Hydroxy-PIPAT is a high affinity 5-HT1A receptor agonist that has the potential for the treatment of disorders of serotonin release. Synonyms: 1-Naphthalenol, 5,6,7,8-tetrahydro-7-[[(2E)-3-iodo-2-propen-1-yl]propylamino]-; 1-Naphthalenol, 5,6,7,8-tetrahydro-7-[(3-iodo-2-propenyl)propylamino]-, (E)-(±)-; 1-Naphthalenol, 5,6,7,8-tetrahydro-7-[[(2E)-3-iodo-2-propenyl]propylamino]-; 5,6,7,8-Tetrahydro-7-[[(2E)-3-iodo-2-propen-1-yl]propylamino]-1-naphthalenol; 1-Naphthalenol, 5,6,7,8-tetrahydro-7-[(3-iodo-2-propenyl)propylamino]-, (E)-; 8-hydroxy-2-(N-n-propyl-N-(3'-iodo-2'-propenyl)amino)tetralin, E-(+-)-isomer. Grade: ≥95%. CAS No. 159651-91-9. Molecular formula: C16H22INO. Mole weight: 371.26. | |
| 8-Hydroxy-PIPAT oxalate | 8-Hydroxy-PIPAT oxalate is a high affinity 5-HT1A receptor agonist (Kd = 0.38 nM) that has the potential for the treatment of disorders of serotonin release. Synonyms: 1-Naphthalenol, 5,6,7,8-tetrahydro-7-[[(2E)-3-iodo-2-propen-1-yl]propylamino]-, ethanedioate (1:1); (RS)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin oxalate; (E)-7-((3-iodoallyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol oxalic acid; 7-{[(2E)-3-Iodo-2-propen-1-yl](propyl)amino}-5,6,7,8-tetrahydro-1-naphthalenol ethanedioate (1:1). Grade: ≥98% by HPLC. CAS No. 1451210-48-2. Molecular formula: C16H22INO.C2H2O4. Mole weight: 461.29. | |
| 8-Hydroxy Pitavastatin | 8-Hydroxy Pitavastatin is one of Pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-8-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; (3R,5S,6E)-7-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; Pitavastatin 8'-Hydroxy Impurity. Grade: ≥90%. CAS No. 224320-09-6. Molecular formula: C25H24FNO5. Mole weight: 437.46. | |
| 8-Hydroxyquinoline b-D-galactopyranoside | 8-Hydroxyquinoline b-D-galactopyranoside is a compound with diverse biomedical applications, showcasing exceptional capabilities in research of microbial infections. Its multifaceted functionality extends towards inhibiting specific cancer-associated enzymes. Synonyms: 8-Hydroxy-1-azanaphthalene b-D-galactoside; HQGal; 8-Quinolinyl β-D-galactopyranoside; Quinolin-8-yl beta-D-galactopyranoside; (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-(quinolin-8-yloxy)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 113079-84-8. Molecular formula: C15H17NO6. Mole weight: 307.30. | |
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