BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. Synonyms: N-[(3s)-2-Oxotetrahydrofuran-3-Yl]butanamide; (S)-N-(2-Oxotetrahydrofuran-3-yl)butyramide. Grades: >98.0%. CAS No. 67605-85-0. Molecular formula: C8H13NO3. Mole weight: 171.19.
N-Carbamoyl-D-glucosamine
N-Carbamoyl-D-glucosamine N is an antibiotic produced by Streptomyces halstedii SF-1993. It has anti-gram-negative bacteria and fungi. Hexose, D-glucosamine and N-acetyl-D-glucosamine can antagonize its activity. Synonyms: D-Glucose, 2-((aminocarbonyl)amino)-2-deoxy-. CAS No. 71868-25-2. Molecular formula: C7H14N2O6. Mole weight: 222.20.
N-Deacyl-A40926 is a glycopeptide antibiotic produced by Actinomadura teichomyceticus. Synonyms: Deacyl-A-40926; DA 40; DA 40926; N-Deacylantibiotic A 40926. CAS No. 118693-63-3. Molecular formula: C71H66Cl2N8O28. Mole weight: 1550.22.
Nebramycin IV is an aminoglycoside antibiotic produced by Streptomyces tenebrarius. Nebramycin IV has a broad antibacterial spectrum and has a strong effect on Gram-positive and negative bacteria and mycobacteria. Synonyms: Nebramycin factor 4; 6''-O-Carbamoylkanamycin B; 6-O-(3-Amino-6-carbamoyl-3-deoxy-α-D-glucopyranosyl)-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine. CAS No. 51736-76-6. Molecular formula: C19H38N6O11. Mole weight: 526.54.
Negamycin
Negamycin is a peptide antibiotic that has broad-spectrum antibacterial activity. Synonyms: L-threo-Hexonic acid, 3,6-diamino-2,3,4,6-tetradeoxy-, 2-(carboxymethyl)-2-methylhydrazide; BRN 4687658. Grades: >98% by HPLC. CAS No. 33404-78-3. Molecular formula: C9H20N4O4. Mole weight: 248.28.
Neihumicin
Neihumicin is produced by the strain of Micromonospora neihuensis Wu, sp. nov. Neihumicin is resistant to beer saccharomyces yeast and Penicillium italium Wehmer, but not to bacteria. Synonyms: Neihumycin; 3,6-Dibenzylidene-2-methoxy-3,6-dihydropyrazin-5-one; NSC617674; (Z,Z)-3,6-Dihydro-5-methoxy-3,6-bis(phenylmethylene)-2(1H)-pyrazinone. CAS No. 111451-12-8. Molecular formula: C19H16N2O2. Mole weight: 304.34.
Nemadectin
The dominant member of a class of milbemycins; shows pronounced nematocidal and insecticidal activity. Synonyms: CL-287088; S541A; LL-F28249 alpha. Grades: >95% by HPLC. CAS No. 102130-84-7. Molecular formula: C36H52O8. Mole weight: 612.79.
Nemotin
It is produced by the strain of Poria corticola B-841, 71280. Nemotin has the activity against gram-positive bacteria, mycobacterium and fungus, and also against gram-negative bacteria, but the activity is weak. Synonyms: BRN 0125855; 5-(1,2-Heptadiene-4,6-diynyl)dihydro-2(3H)-furanone; 5-(Hepta-1,2-diene-4,6-diyn-1-yl)oxolan-2-one. Grades: 98%. CAS No. 502-12-5. Molecular formula: C11H8O2. Mole weight: 172.18.
Nemotinic acid
It is produced by the strain of Poria corticola B-841, 71280. Nemotinic acid has the activity against gram-positive bacteria, mycobacterium and fungus, and also against gram-negative bacteria, but the activity is weak. And its activity is stronger than Nemotin. Synonyms: BRN 1707406; 4-hydroxyundeca-5,6-diene-8,10-diynoic acid; 4-hydroxyundeca-5,6-dien-8,10-diynoic acid. Grades: ≥95%. CAS No. 539-98-0. Molecular formula: C11H10O3. Mole weight: 190.19.
Neoaureothin
Neoaureothin is a metabolite produced by Streptomyces. It acts as an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50 = 1.75 nM). Synonyms: 4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[(2R,4Z)-tetrahydro-4-[(2E,4E,6E)-2,4,6-trimethyl-7-(4-nitrophenyl)-2,4,6-heptatrien-1-ylidene]-2-furanyl]-; 2-Methoxy-3,5-dimethyl-6-[(2R,4Z)-tetrahydro-4-[(2E,4E,6E)-2,4,6-trimethyl-7-(4-nitrophenyl)-2,4,6-heptatrien-1-ylidene]-2-furanyl]-4H-pyran-4-one; 4H-Pyran-4-one, 2-methoxy-3,5-dimethyl-6-[tetrahydro-4-[2,4,6-trimethyl-7-(4-nitrophenyl)-2,4,6-heptatrienylidene]-2-furanyl]-, (Z,E,E,E)-(+)-; (+)-Spectinabilin; NSC 260179; Spectinabilin; Spectinabiline. Grades: ≥98%. CAS No. 59795-94-7. Molecular formula: C28H31NO6. Mole weight: 477.55.
Neocarzinostatin chromophore
Neocarzinostatin chromophore is a macromolecular chromoprotein enediyne antitumor antibiotic produced by Streptomyces macromomyceticus. CAS No. 79633-18-4. Molecular formula: C35H33NO12. Mole weight: 659.6.
Neocopiamycin A
Neocopiamycin A is produced by the strain of Str. hygroscopicus var. crystallogenes. It is broad-spectrum resistant to gram-positive bacteria, yeast and filamentous fungi. Synonyms: Neocopiamycin. CAS No. 89989-28-6. Molecular formula: C53H93N3O17. Mole weight: 1044.31.
Neocopiamycin B
Neocopiamycin B is produced by the strain of Str. hygroscopicus var. crystallogenes. Its antifungal activity is stronger than that of copiamycin and Neocopiamycin A. Molecular formula: C54H95N3O16. Mole weight: 1042.34.
Neoenactin A
Neoenactin A is originally isolated from Streptoverticillium olivoreticuli subsp. neoenacticus. It has strong anti-yeastlike and filamentous fungal effects. Synonyms: Propanamide,2-amino-N-(3,10-dioxohexadecyl)-N,3-dihydroxy-, (S)-. CAS No. 88231-85-0. Molecular formula: C19H36N2O5. Mole weight: 372.50.
Neoenactin B1
Neoenactin B1 is originally isolated from Streptoverticillium olivoreticuli subsp. neoenacticus. It has strong anti-yeastlike and filamentous fungal effects. Molecular formula: C20H38N2O5. Mole weight: 386.52.
Neoenactin B2
Neoenactin B2 is originally isolated from Streptoverticillium olivoreticuli subsp. neoenacticus. It has strong anti-yeastlike and filamentous fungal effects. CAS No. 88231-87-2. Molecular formula: C20H38N2O5. Mole weight: 386.52.
Neogrifolin
Neogrifolin is a natural compound isolated from the edible bodies of the mushroom Albatrellus confluens, and it shows antimicrobial activities against Bacillus cereus and Enterococcus faecalis. Synonyms: 5-Methyl-6-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-1,3-benzenediol; E,E,5-Methyl-4-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-1,3-benzenediol. Grades: 98.5%. CAS No. 23665-96-5. Molecular formula: C22H32O2. Mole weight: 328.49.
Neohydroxyaspergillic acid
Neohydroxyaspergillic acid is an antibiotic produced by Aspergillus sckrotiorum, which is active against some bacteriophages and fungus. Synonyms: NSC 613947; 2(1H)-Pyrazinone, 1-hydroxy-6-[(1S)-1-hydroxy-2-methylpropyl]-3-(2-methylpropyl)-. Grades: ≥95%. CAS No. 72598-34-6. Molecular formula: C12H20N2O3. Mole weight: 240.30.
Neomethymycin
Neomethymycin is a macrolide antibiotic produced by Str. venezuelae WC-3627 and WC-3629. It has activity against gram-positive bacteria and a few gram-negative bacteria. CAS No. 497-73-4. Molecular formula: C25H43NO7. Mole weight: 469.61.
Neomycin B
Neomycin B is originally isolated from Str. fradiae 3535. It is mainly resistant to bacteria and mycobacteria, and its activity is the strongest of the three components. Synonyms: Framycetin; Mycifradin; Soframycin; Dekamycin II; O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?3)-O-β-D-ribofuranosyl-(1?5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1?4)]-2-deoxy-D-streptamine. Grades: ≥95%. CAS No. 119-04-0. Molecular formula: C23H46N6O13. Mole weight: 614.64.
Neomycin C
Neomycin C is originally isolated from Str. fradiae 3535. It is mainly resistant to bacteria and mycobacteria. Synonyms: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside. Grades: 99%. CAS No. 66-86-4. Molecular formula: C23H46N6O13. Mole weight: 614.64.
Neomycin trisulfate
Neomycin trisulfate is an aminoglycoside antibiotic. It can be used to prevent and treat gastrointestinal infections caused by gram-negative bacteria such as Salmonella and Escherichia coli. Synonyms: (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((2R,3S,4R,5S)-5-(((1R,2R,3S,5R,6S)-3,5-diamino-2-(((2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl)oxy)-6-hydroxycyclohexyl)oxy)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)oxy)tetrahydro-2H-pyran-3,4-diol trisulfate; Framycetin sulfate; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-b-L-idopyranosyl)-b-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-a-D-glucopyranoside trisulfate salt. CAS No. 879480-48-5. Molecular formula: C23H46N6O13.3H2SO4. Mole weight: 908.88.
Neosolaniol
Neosolaniol is a kind of type A trichothecene mycotoxin found in Fusarium. Synonyms: Solaniol. Grades: ≥98% by HPLC. CAS No. 36519-25-2. Molecular formula: C19H26O8. Mole weight: 382.40.
Neosordarin
Neosordarin is originally isolated from Sordaria araneosa Cain. Neosordarin has antifungal activity and inhibits S. Cerevisia with the IC50 of 0.2-0.3 μg/mL. Molecular formula: C36H50O11. Mole weight: 658.77.
Neotelomycin
Neotelomycin is originally isolated from Str. sp. 128 and it is resistant to gram-positive bacteria. CAS No. 11015-47-7. Molecular formula: C59H77N13O19. Mole weight: 1272.32.
Neoviridogrisein I
It is produced by the strain of Str. griseoviridus P8648. Neoviridogrisein I has been used to resist gram-positive bacteria and mycoplasma. Synonyms: (3-D-proline)-[6-(L-2-amino-butyric acid)]-etamycin-A. CAS No. 66002-39-9. Molecular formula: C45H64N8O10. Mole weight: 877.03.
Neoviridogrisein II
It is produced by the strain of Str. griseoviridus P8648. Neoviridogrisein II has been used to resist gram-positive bacteria and mycoplasma. Synonyms: 3-Phenyl-4,6,10,13,22-pentamethyl-9-(1,2-dimethylpropyl)-18-(2-methylpropyl)-21-[[(3-hydroxy-2-pyridyl)carbonyl]amino]-15,16-propano-1-oxa-4,7,10,13,16,19-hexaazacyclodocosane-2,5,8,11,14,17,20-heptone; neoviridogrisein ii. Molecular formula: C44H62N8O10. Mole weight: 863.01.
(-)-Neplanocin A
(-)-Neplanocin A potently and irreversibly inactivates SAH hydrolase (Ki = 8.39 nM). It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity. Neplanocin A is more potent against vesicular stomatitis than the reversible SAH hydrolase inhibitor 3-deazaneplanocin (ID50 = 0.07 and 0.3 μg/ml, respectively). Uses: Antibiotics, antineoplastic. Synonyms: NPC-A; (-)-9-(trans-2,trans-3-Dihydroxy-4-(hydroxymethyl)-cyclopent-4-enyl)-adenine; 5-(6-Amino-purin-9-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol. Grades: ≥98%. CAS No. 72877-50-0. Molecular formula: C11H13N5O3. Mole weight: 263.25.
N-ε-Acetimidoyl-L-lysine
L-NIL is a potent and selective inhibitor of inducible NO synthase with IC50s of 92 and 3.3 μM for rat brain constitutive NO synthase and mouse inducible NO synthase, respectively. Synonyms: H-Lys(Acetimidoyl)-OH; N-(5-Amino-5-carboxypentyl)acetamidine; 6-Acetimidamido-2-aminohexanoic acid; L-NIL. Grades: 99%. CAS No. 53774-63-3. Molecular formula: C8H17N3O2. Mole weight: 187.24.
N(6)-Carboxymethyllysine (CML), also known as N(epsilon)-(carboxymethyl)lysine, is an advanced glycation endproduct(AGE). CML has been the most used marker for AGEs in food analysis. Uses: Cel and cml are two stable, nonenzymatic chemical modifications of protein lysine residues resulting from glycation and oxidation reactions. Synonyms: Lys(Cm); 2-Amino-6-(carboxymethyl-amino)-hexanoic Acid; N6-(Carboxymethyl)lysine; N6-(Carboxymethyl)-L-lysine; CML; Nε-(1-Carboxymethyl)-L-lysine; Ne-Carboxymethyl-L-lysine; NECML; N(epsilon)-(Carboxymethyl)lysine; (S)-2-Amino-6-(carboxymethylamino)hexanoic acid; (2S)-2-amino-6-(carboxymethylamino)hexanoic acid; n'-(carboxymethyl)lysine. Grades: ≥ 97% (Assay by titration). CAS No. 5746-4-3. Molecular formula: C8H16N2O4. Mole weight: 204.22.
N-ε-Isopropyl-L-lysine is an alkylated version of Lysine. H-Lysine(Isopropyl)-OH was found in the plasma and urine of rats fed with isopropylated casein. Synonyms: H-Lys(Isopropyl)-OH. CAS No. 5977-9-3. Molecular formula: C9H20N2O2. Mole weight: 188.27.
Netilmicin Sulfate is a semisynthetic, water-soluble aminoglycoside antibiotic obtained by chemical modification of sisomicin. It is active against both Gram-positive and Gram-negative bacteria. Uses: Anti-bacterial agents. Synonyms: Netilmicin Sulfate; Sch-20569; Sch 20569; Sch20569. Grades: >98%. CAS No. 56391-57-2. Molecular formula: C42H92N10O34S5. Mole weight: 1441.55.
Netropsin
Netropsin is isolated from Streptomyces netropsis as a basic polypeptide. It can specific bind to A-T areas of DNA that is very useful to genetic research. Netropsin can disrupt the cell cycle, prolonging G and arresting in G. Netropsin has antibiotic and antiviral activity. It has been shown that Netropsin is active against Gram-positive and Gram-negative bacteria. Synonyms: Antibiotic 1142; Antibiotic T-1384; Antibiotic T 1384; Sinanomycin; Congocidin; Congocidine; F6; F-9; IA-887; IA 887; K-117; K 117; N-(3-amino-3-iminopropyl)-4-(4-(2-guanidinoacetamido)-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxamide. Grades: ≥98%. CAS No. 1438-30-8. Molecular formula: C18H26N10O3. Mole weight: 430.47.
Netropsin Dihydrochloride
It is a basic cytotoxic polypeptide produced by the strain of Streptomyces netropsis. It is a DNA minor groove binding ligand. Synonyms: Congocidin Dihydrochloride; Sinanomycin Dihydrochloride; Netropsin Dihydrochloride; Congocidine Dihydrochloride; N'-(2-amidinoethyl)-4-(2-guanidinoacetamido)-1,1'-dimethyl-N,4'-Bi[pyrrole-2-carboxamide] Dihydrochloride; 4-[[2-[ (Aminoiminomethyl) amino]acetyl]amino]-N-[5-[[ (3-amino-3-iminopropyl) amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-1-methyl-1H-pyrrole-2-carboxamide Dihydrochloride. Grades: ≥98%. CAS No. 18133-22-7. Molecular formula: C18H26N10O3.2HCl. Mole weight: 503.40.
Neuchromenin
Neuchromenin is purified from the culture broth of Eupenicillium javanicum var. meloforme PF1181. Neuchromenin is an inducer of neurite outgrowth of PC12 cells at concentration of 2.5-10 ug/ml. Synonyms: (-)-2,3-Dihydrocitromycin; 4H,5H-Pyrano[3,2-c][1]benzopyran-4-one, 2,3-dihydro-8,9-dihydroxy-2-methyl-, (2S)-; (-)-Neuchromenin. Grades: 98.0%. CAS No. 180964-26-5. Molecular formula: C13H12O5. Mole weight: 248.23.
Neuromedin C
Neuromedin C (NMC) is a decapeptide that acts as a growth factor in a variety of tumors. Synonyms: Neuromedin C (porcine); Gly-asn-his-trp-ala-val-gly-his-leu-met-NH2; GRP (18-27) (human, porcine, canine); Bombesin decapeptide; Grp-10; Gastrin releasing peptide 10; Canine gastrin-releasing peptide 10; Gastrin releasing peptide (18-27); glycyl-L-asparagyl-L-histidyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide. Grades: ≥95% by HPLC. CAS No. 81608-30-2. Molecular formula: C50H73N17O11S. Mole weight: 1120.29.
Neuromedin (U8), porcine
Neuromedin (U8), porcine has potent agonist activity for neuromedin resceptors NMUR1 and NMUR2. Synonyms: Neuromedin U-8; L-tyrosyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-asparaginamide; H-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2. Grades: 95% by HPLC. CAS No. 98395-75-6. Molecular formula: C54H78N16O10. Mole weight: 1111.30.
Neuropeptide Y (free acid) (human, rat)
Neuropeptide Y is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. Synonyms: H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2; NPY (free acid) (human, rat); Neuropeptide Y, human, rat. Grades: ≥95%. CAS No. 99575-89-0. Molecular formula: C189H285N55O57S. Mole weight: 4271.74.
N-Formylfortimicin A
N-Formylfortimicin A is produced by the strain of Micromonospora SF-1854. It has anti-gram positive and negative bacteria activity. The activity was 8-16 times weaker than that of Fortimycin A, but the effect on Salmonella, pseudomonas, and Streptococcus faecalis is similar to that of Fortimycin A. Synonyms: N-((1R,2R,3S,4S,5R,6R)-4-amino-3-(((2R,3R,6R)-3-amino-6-((R)-1-aminoethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,5-dihydroxy-6-methoxycyclohexyl)-2-formamido-N-methylacetamide. Grades: >98%. CAS No. 74228-81-2. Molecular formula: C18H35N5O7. Mole weight: 433.50.
N-Hexadecanoylhomoserine lactone is a herbicide produced by Methanol-utilising bacteria. Synonyms: N-hexadecanoyl-L-Homoserine lactone; C16-HSL; N-(hexadecanoyl)-homoserine lactone; Hexadecanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-. Grades: >99% by HPLC. CAS No. 87206-01-7. Molecular formula: C20H37NO3. Mole weight: 339.51.
Additive in to DCC method of peptide synthesis used to improve yield of optically pure product. Synonyms: 2-Hydroxy-1H-isoindole-1,3(2H)-dione Phthaloxime. Grades: ≥ 99% (Assay). CAS No. 524-38-9. Molecular formula: C8H5NO3. Mole weight: 163.13.