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The smallest member of the macrotetrolide complex produced by a range of streptomyces species; a monovalent cation ionophore with high selectivity for ammonium and potassium. It is resistant to gram-positive bacteria, mycobacteria and fungi, and it also inhibits L cells. Synonyms: Werramycin-A; NSC 52141; BRN 0076434; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo(32.2.1.17, 10.116, 19.125, 28)tetracontane-3, 12, 21, 30-tetrone, 2,5,11,14,20,23,29,32-octamethyl-(8CI). Grades: >99% by HPLC. CAS No. 6833-84-7. Molecular formula: C40H64O12. Mole weight: 736.93.
Norcantharidin
It is an antitumor drug and a PP1 and PP2A inhibitor. It is a modified product of the natural antitumor drug cantharidin. It reduces its urinary system toxicity but not its antitumor efficacy after is demethylated. It induces cell apoptosis and acts as an antineoplastic. Synonyms: rel-(3aR,4S,7R,7aS)-Hexahydro-4,7-epoxyisobenzofuran-1,3-dione; (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-epoxyisobenzofuran-1,3-dione; 7-Oxabicyclo[2.2.1]heptane-exo-cis-2,3-dicarboxylic anhydride; Demethylcantharidin; Isocantharidin; NSC 59023; NCTD; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aR,4S,7R,7aS)-rel-; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-, (3aα, 4β, 7β, 7aα)-; 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride, exo-; exo-7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid anhydride. Grades: ≥98%. CAS No. 29745-04-8. Molecular formula: C8H8O4. Mole weight: 168.15.
Norfloxacin
Norfloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase. It is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. It is approved for use in children older than one year of age. However, it is associated with a number of rare serious adverse reactions as well as spontaneous tendon ruptures and irreversible peripheral neuropathy. Uses: Anti-bacterial agents; enzyme inhibitors; nucleic acid synthesis inhibitors. Synonyms: Noroxin; Chibroxin; AM-715; MK-366; AM 715; MK 366; AM715; MK366; 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid; Baccidal; Barazan; Chibroxine; N-Desmethylpefloxacin; Sebercim; Zoroxin. Grades: >98%. CAS No. 70458-96-7. Molecular formula: C16H18FN3O3. Mole weight: 319.33.
Nornidulin
A depsidone produced by several fungal species; has potent and selective antibacterial activity; has potential as an anti-inflammatory agent. Synonyms: Ustin; 2,4,7-Trichloro-3,8-dihydroxy-1,9-dimethyl-6-(1-methyl-1-propenyl)-11H-dibenzo(b,E)(1,4)dioxepin-11-one. Grades: >99% by HPLC. CAS No. 33403-37-1. Molecular formula: C19H15Cl3O5. Mole weight: 429.68.
Norplicacetin
It is originally isolated from Str. plicatus NCIB 11305. And it has the effect of anti-gram-positive bacteria and mycobacterium. Molecular formula: C24H33N5O7. Mole weight: 503.55.
Nothramicin
It is an anthracycline antibiotic with anti-mycobacterial activity produced by the strain of Nocardia sp. MJ 896-43F. Synonyms: 3,4,10,12-tetrahydroxy-2,7-dimethoxy-3-methyl-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-(dimethylamino)-3-methylhexopyranoside. Grades: >95%. CAS No. 205752-47-2. Molecular formula: C30H37NO11. Mole weight: 587.61.
Notonesomycin A
Notonesomycin A is originally isolated from Str. aminophilus subsp. notonesogenes 647-AV1. It has the effect of resisting plant pathogenic bacteria and fungi, and its effect is similar to that of Validamycin. Synonyms: NSC608604. CAS No. 102525-63-3. Molecular formula: C68H111NO30S. Mole weight: 1454.66.
Nourseothricin sulfate
An antibiotic in the streptothricin class of antibiotics. Synonyms: streptothricin. CAS No. 96736-11-7. Molecular formula: C19H36N8O12S. Mole weight: 600.60.
Novobiocin
Novobiocin is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, thus disrupting the interaction of both p23 and Hsp70 co-chaperones with the Hsp90 complex. (IC50=700μmol/L). Synonyms: Streptonivicin; Inamycin; Albamycin; Cathomycin; Cardelmycin; Spheromycin; Antibiotic PA-93; Novobiocina; Benzamide, N-(7-((3-O-(aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-beta-L-lyxo-hexopyranosyl)oxy)-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl)-4-hydroxy-3-(3-methyl-2-butenyl)-. Grades: >95%. CAS No. 303-81-1. Molecular formula: C31H36N2O11. Mole weight: 612.62.
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt is a chromogenic substrate for plasmin determination, serine protease activity and fibrinogen decomposition determination. Synonyms: N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt; Tos-GPK-pNA; Tos-Gly-Pro-Lys-pNA acetate; N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate. Grades: ≥98% by TLC. CAS No. 88793-79-7. Molecular formula: C28H38N6O9S. Mole weight: 634.7.
NS
NS is a mixture of polysaccharides produced by Streptomyces flavochromogenes 280, consisting of NS1~NS17. It has inhibitory effect against α-amylase and glucoamylase.
NS-5
NS-5 is a beta-lactam antibiotic produced by Streptomyces cattaleya. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Molecular formula: C11H16N2O3S. Mole weight: 256.32.
N-Succinimidyl 11-(maleimido)undecanoate
Maleimide-C10-NHS ester is a PROTAC linker, which is composed of alkyl chains. Maleimide-C10-NHS ester can be used to synthesize a range of PROTACs. Synonyms: KMUS; Maleimide-C10-NHS ester; N-Succinimidyl 11-maleimidoundecanoate; 11-Maleimidoundecanoic Acid N-Succinimidyl Ester; 2,5-dioxopyrrolidin-1-yl 11-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoate; Maleimide-(CH2)10-COONHS; 11-Maleimidoundecanoicacid-NHS; 11-(Maleimido)undecanoic acid N-succinimidyl ester; VZ21668; 11-Maleimidoundecanoic acid-NHS (KMUS); 2,5-Dioxo-3-pyrroline-1-undecanoic acid succinimidyl ester. Grades: 95%. CAS No. 87981-04-2. Molecular formula: C19H26N2O6. Mole weight: 378.42.
NT-2
NT-2 is a toxin produced by Fusarium sporotrichioides M-1. Molecular formula: C19H26O8. Mole weight: 382.4.
NT-3
NT-3 is a toxin produced by Fusarium sporotrichioides M-1. Molecular formula: C17H24O7. Mole weight: 340.37.
OA-6129 A is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Synonyms: Antibiotic OA 6129A; OA 6129A; OA-6129A. CAS No. 82475-11-4. Molecular formula: C20H31N3O7S. Mole weight: 457.5.
OA-6129 B1
OA-6129 B1 is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Synonyms: Antibiotic OA 6129B1; OA 6129B1; OA-6129B1. Molecular formula: C20H31N3O8S. Mole weight: 473.5.
OA-6129 B2
OA-6129 B2 is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Synonyms: Antibiotic OA 6129B2; OA 6129B2; OA-6129B2. CAS No. 82475-10-3. Molecular formula: C20H31N3O8S. Mole weight: 473.5.
OA-6129 C
OA-6129 C is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. Synonyms: Antibiotic OA 6129C; OA 6129C; OA-6129C. Molecular formula: C20H31N3O11S2. Mole weight: 553.6.
OA-6129 D
OA-6129 D is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. It is also effective against dehydrodipeptidase and Comamonas terrigena B-996. Synonyms: Antibiotic OA 6129D; OA 6129D; OA-6129D. CAS No. 85414-25-1. Molecular formula: C20H33N3O8S. Mole weight: 475.6.
OA-6129 E
OA-6129 E is a carbapenem antibiotic produced by Streptomyces sp. OA-6129. It inhibits gram-positive, gram-negative bacteria and beta-lactamase. It is also effective against dehydrodipeptidase and Comamonas terrigena B-996. Synonyms: Antibiotic OA 6129E; OA 6129E; OA-6129E. CAS No. 85414-26-2. Molecular formula: C21H35N3O8S. Mole weight: 489.6.
O-Acetylcrinipellin A
It is produced by the strain of Crinipellis stipitaria. It has anti-gram-positive bacteria and Aldrin ascites carcinoma activity. Synonyms: Acetylcrinipellin A; Crinipellin; Crinipellin A acetate; 7a,9a-dimethyl-3-methylidene-2,9-dioxo-7-(propan-2-yl)decahydro-1aH,5H-pentaleno[6a',1':5,6]pentaleno[1,6a-b]oxiren-8-yl acetate. CAS No. 97315-00-9. Molecular formula: C22H28O5. Mole weight: 372.46.
It is a β-lactone antibiotic that is found in Pseudomonas fluorescens and is active against Staphylococcus aureus, Streptococcus faecalis, Klebsiella pneumoniae and Pseudomonas vulgaris. Synonyms: Benzamide, 2,3-dihydroxy-N-[(2R,3S)-2-[(4-nitrophenyl)methyl]-4-oxo-3-oxetanyl]-; 2,3-dihydroxy-N-((2R,3S)-2-(4-nitrobenzyl)-4-oxooxetan-3-yl)benzamide; Benzamide, 2,3-dihydroxy-N-[2-[(4-nitrophenyl)methyl]-4-oxo-3-oxetanyl]-, (2R-cis)-; (+)-Obafluorin; N-[(3S)-2-Oxo-4β-(4-nitrobenzyl)oxetan-3β-yl]-2,3-dihydroxybenzamide. Grades: ≥98%. CAS No. 92121-68-1. Molecular formula: C17H14N2O7. Mole weight: 358.30.
Obscurolide A1 is a weak phosphodiesterase inhibitor isolated from Streptomyces viridochromogenes. Synonyms: 4-[[2-[(E)-3-hydroxybut-1-enyl]-5-oxooxolan-3-yl]amino]benzoic acid. Grades: ≥98%. CAS No. 144397-99-9. Molecular formula: C15H17NO5. Mole weight: 291.30.
O-Carbamoyl-D-serine
O-Carbamoyl-D-serine is an antibiotic produced by Str. polychromogenes. It can inhibit the synthesis of bacterial cell wall and has weak anti-gram-positive bacteria activity. Molecular formula: C4H8N2O4. Mole weight: 148.12.
Ochracenomicin A
It is produced by the strain of Amicolatopsis sp. MJ 950-891. Ochracenomicin A has a strong effect against gram-positive bacteria (including MRSA strain), and also against gram-negative bacteria and candida albicans. Synonyms: 4a,8,12b-trihydroxy-3-methyl-3,4,4a,12b-tetrahydrotetraphene-1,7,12(2H)-trione. Molecular formula: C19H16O6. Mole weight: 340.33.
Ochracenomicin C
It is produced by the strain of Amicolatopsis sp. MJ 950-891. Ochracenomicin C has a weak antibacterial effect. Molecular formula: C19H20O5. Mole weight: 328.36.
Ochratoxin B
Ochratoxin B is an analogue of Ochratoxin A. Ochratoxins are mycotoxins produced by Aspergillus and Penicillium. Grades: >99% by HPLC. CAS No. 4825-86-9. Molecular formula: C20H19NO6. Mole weight: 369.37.
Ochratoxin C
A minor component of the ochratoxin complex produced by Aspergillus orchraceus and penicillium sp. It is a mycotoxin associated with food spoilage. It is the ethyl ester of ochratoxin A and represents a different hazard to the acidic major components ochratoxins A and B. Synonyms: Ochratoxin A ethyl ester; ethyl ((R)-5-chloro-8-hydroxy-3-methyl-1-oxoisochromane-7-carbonyl)-L-phenylalaninate; L-Phenylalanine, N-((5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl)-, ethyl ester, (R)-; N-[[(3R)-5-chloro-3,4-dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine, ethyl ester. Grades: >95% by HPLC. CAS No. 4865-85-4. Molecular formula: C22H22ClNO6. Mole weight: 431.87.
Octacosamicin A
Octacosamicin A is originally isolated from Amycolatops azurea MG 398-hF9 (FERM P-8865). It has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak. Synonyms: Antibiotic MG 398HF9A; Glycine, N-(28-((aminoiminomethyl)hydroxyamino)-2,3,5,7-tetrahydroxy-1,19-dioxo-12,14,20,22-octacosatetraenyl)-. Grades: >95%. CAS No. 122005-25-8. Molecular formula: C31H52N4O9. Mole weight: 624.76.
Octacosamicin B
Octacosamicin B is originally isolated from Amycolatops azurea MG 398-hF9 (FERM P-8865). It has the function of resisting bacterium, yeast, and filamentous fungus, but the function of resisting bacterium is weak. CAS No. 122005-24-7. Molecular formula: C32H54N4O9. Mole weight: 638.79.
Octadecanoyl-L-homoserine lactone
An active quorum sensing modulator first recognised in sinorhizobium meliloti. Synonyms: C18-HSL; N-Octadecanoyl-L-homoserine lactone; N-(2-oxooxolan-3-yl)octadecanamide; N-stearoyl-L-homoserine lactone; C18-L-HSL; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octadecanamide. Grades: >99% by HPLC. CAS No. 479050-96-9. Molecular formula: C22H41NO3. Mole weight: 367.57.
Octanoyl-L-homoserine lactone
An active quorum sensing modulator first recognised in yersinia pseudotuberculosis. It is produced by the strain of Agrobacterium vitis and Nitrosomonas europeae. Synonyms: C8-HSL; OHL; N-Octanoyl-L-homoserine lactone; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide; HTF. Grades: >99% by HPLC. CAS No. 147852-84-4. Molecular formula: C12H21NO3. Mole weight: 227.30.
Octapeptin C1
It is a peptide antibiotic produced by the strain of Bacillus circulans 333-25. It has anti-gram-positive and gram-negative bacteria activity, but no effect on pseudomonas aeruginosa. It inhibits E. coli and Klebsiella pneumoniae with IC50 of 0.95 mg/kg (Mice, subcutaneous). Synonyms: Antibiotic 333-25; Octapeptin A1, 1-(N(sup 2)-(3-hydroxy-6-methyl-1-oxooctyl)-D-2,4-diaminobutanoic acid)-4-D-phenylalanine-; N2-[N2-(3-Hydroxy-6-methyl-1-oxooctyl)-D-DAB-]cyclo[L-DAB*-L-DAB-D-Phe-L-Leu-L-DAB-L-DAB-L-Leu-]. CAS No. 59217-95-7. Molecular formula: C50H87N13O10. Mole weight: 1030.31.
O-Demethylpaulomycin A
O-Demethylpaulomycin A is a quinone antibiotic produced by Streptomyces paulus. It has the effect of anti-gram-positive bacteria, and its activity is lower than that of Pauloycin. Synonyms: 5-[6-(acetyloxymethyl)-4-[4,5-dihydroxy-6-methyl-5-[1-(2-methylbutanoyloxy)ethyl]oxan-2-yl]oxy-3-hydroxy-5-[(E)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylic acid, 5-(6-O-acetyl-3-O-(2,6-dideoxy-4-C-((S(S))-1-(2-methyl-1-oxobutoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-4-O-((Z)-2-isothiocyanato-1-oxo-2-butenyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-, (S)-. CAS No. 113603-74-0. Molecular formula: C33H44N2O17S. Mole weight: 772.77.
O-Demethylpaulomycin B
O-Demethylpaulomycin B is a quinone antibiotic produced by Streptomyces paulus. It has the effect of anti-gram-positive bacteria, and its activity is lower than that of Pauloycin. Synonyms: 5-[6-(acetyloxymethyl)-4-[4,5-dihydroxy-6-methyl-5-[1-(2-methylpropanoyloxy)ethyl]oxan-2-yl]oxy-3-hydroxy-5-[(E)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylic acid, 5-(6-O-acetyl-3-O-(2,6-dideoxy-4-C-((S)-1-(2-methyl-1-oxopropoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-4-O-(2-isothiocyanato-1-oxo-2-butenyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-, (S)-. CAS No. 113592-08-8. Molecular formula: C32H42N2O17S. Mole weight: 758.74.
OF4949 I
OF4949 I is an aminopeptidase B produced by Penicillum rugulosum OF4949. Synonyms: OF 4949I; OF 4949-I; OF4949I. CAS No. 93375-51-0. Molecular formula: C23H26N4O8. Mole weight: 486.5.
OF4949 II
OF4949 II is an aminopeptidase B produced by Penicillum rugulosum OF4949. Synonyms: OF 4949II; OF 4949-II; OF4949II. CAS No. 93375-50-9. Molecular formula: C22H24N4O8. Mole weight: 472.4.
OF4949 III
OF4949 III is an aminopeptidase B produced by Penicillum rugulosum OF4949. Synonyms: OF 4949III; OF 4949-III; OF4949III. CAS No. 107140-32-9. Molecular formula: C23H26N4O7. Mole weight: 470.5.
OF4949 IV
OF4949 IV is an aminopeptidase B produced by Penicillum rugulosum OF4949. Synonyms: OF 4949IV; OF 4949-IV; OF4949IV. CAS No. 107140-31-8. Molecular formula: C22H24N4O7. Mole weight: 456.4.