BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Oxo-Benzygluanine-d5 | 8-Oxo-Benzygluanine-d5. Synonyms: 2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one-d5. Molecular formula: C12H6D5N5O2. Mole weight: 262.28. |  |
| 8-Oxo-Benzylguanine | As a derivative of O-Benzylguanine, 8-Oxo-Benzylguanine is a reversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase and O-Benzylguanine is known to assist in the protection against carcinogenic and therapeutic alkylating agents. Synonyms: 2-Amino-7,9-dihydro-6-(phenylmethoxy)-8H-purin-8-one; NU 6043. CAS No. 158754-46-2. Molecular formula: C12H11N5O2. Mole weight: 257.25. | |
| 8-Oxo-dATP | 8-Oxo-dATP is a nucleotide analog mainly acting as a substrate for DNA polymerase during DNA enhancement and repair. 8-Oxo-dATP is involved in cellular processes related to oxidative stress and DNA damage. It can be used to study the effects of oxidative DNA damage and its association with diseases such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyadenosine-5'-Triphosphate; 8-Hydroxy-2'-deoxyadenosine 5'-triphosphoric acid. Grade: ≥ 95% by HPLC. Molecular formula: C10H16N5O13P3 (free acid). Mole weight: 507.18 (free acid). | |
| 8-Oxo-desacetylated famciclovir | An impurity of Famciclovir. Famciclovir is used for the treatment of various herpesvirus infections, most commonly for herpes zoster. Synonyms: 4-(2-amino-8-oxo-7H-purin-9(8H)-yl)-2-(hydroxymethyl)butyl acetate. Grade: > 95%. Molecular formula: C12H17N5O4. Mole weight: 295.30. | |
| 8-oxo-dG-CE Phosphoramidite | 8-oxo-dG-CE Phosphoramidite is an indispensable compound assuming a pivotal role in oligonucleotide research and development. Its contributes to the exploration of therapeutic drugs aimed at DNA repair and ailments associated with oxidative stress. Synonyms: 5'-Dimethoxytrityl-N2-isobutyryl-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-dG(ibu) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(2-isobutyramido-6,8-dioxo-1,6,7,8-tetrahydro-9H-purin-9-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; DNA 8-oxo-G(iBu) amidite. Grade: 95%. CAS No. 143060-53-1. Molecular formula: C44H54N7O9P. Mole weight: 855.93. | |
| 8-OXO-dG(dmf) Phosphoramidite | 8-OXO-dG(dmf) Phosphoramidite is a modified phosphoramidite in which the guanine base is oxidized at the 8-position to form 8-oxo-guanine, with the exocyclic amine at the 2-position protected by a dimethylformamidine (dmf) group. The sugar moiety is functionalized with a 3'-cyanoethyl (CE) phosphoramidite group for incorporation into oligonucleotides via automated DNA synthesis. This modification mimics oxidative DNA damage, making it a valuable tool for studying the biological effects of oxidative stress, DNA repair mechanisms, and mutagenesis. It is widely used in molecular biology and biochemistry research to investigate the role of 8-oxo-guanine in genomic stability and disease processes. Synonyms: OXO-dG(N-dmf) Phosphoramidite; OXO-dG(N-dmf) CE Phosphoramidite; 5'-Dimethoxytrityl-N2-dimethylformamidine-8-oxo-deoxyguanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-OXO-2'-deoxy-G(DMF) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-dimethylformamidine-8-oxo-2'-deoxyguanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 8-OXO-dG(dmf) CE Phosphoramidite; 8-OXO-dG(dmf) 3'-CE Phosphoramidite. Grade: ≥98%. CAS No. 1850359-96-4. Molecular formula: C43H53N8O8P. Mole weight: 840.92. | |
| 8-Oxo-dGDP | 8-Oxo-dGDP, a nucleotide analog, serves as a substrate for DNA polymerases and as a regulator for those enzymes associated with DNA repair in biochemical studies. Furthermore, it is employed to explore the involvement of oxidative stress in cancer and neurodegenerative diseases, such as Alzheimer's and Parkinson's. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H15N5O11P2 (free acid). Mole weight: 443.20 (free acid). | |
| 8-Oxo-dGMP | 8-Oxo-dGMP is a nucleotide derivative commonly used in research to study DNA damage and repair mechanisms. It is often used to detect and quantify oxidation damage to DNA induced by reactive oxygen species, as well as to investigate the role of 8-oxo-dG in mutagenesis and carcinogenesis. 8-Oxo-dGMP has potential therapeutic applications for the treatment of diseases associated with oxidative stress, such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O8P (free acid). Mole weight: 363.22 (free acid). | |
| 8-Oxo-dGP4 | 8-Oxo-dGP4 is a chemical compound used in biomedical research for the study of DNA damage and repair mechanisms. It is a modified form of the nucleoside guanosine and is commonly utilized to identify and quantify oxidative damage to DNA caused by reactive oxygen species. Additionally, 8-Oxo-dGP4 has potential in the development and screening of drugs for the treatment of diseases related to DNA damage, such as cancer and neurodegenerative disorders. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-tetraphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H17N5O17P4 (free acid). Mole weight: 603.16 (free acid). | |
| 8-Oxo-dGTP | 8-Oxo-dGTP can increase the rate of genetic mutation via interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. Uses: 8-oxo-dgtp is an agent that increase the rate of genetic mutation. Synonyms: 8-Oxo-2'-deoxyguanosine-5'-Triphosphate; 8-Oxodeoxyguanosine triphosphate; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate. Grade: ≥95% by AX-HPLC. CAS No. 139307-94-1. Molecular formula: C10H16N5O14P3 (free acid). Mole weight: 523.18 (free acid). | |
| 8-Oxo-GTP | 8-Oxo-GTP, a nucleotide with modifications, is a valuable tool in discovering RNA oxidative and repair mechanisms. Its versatile use also includes investigations into Alzheimer's and Parkinson's, as well as cancer. Its potential to provide antioxidant properties demonstrates promise for defending against oxidative stress in various disease states. Synonyms: 8-Oxoguanosine-5'-Triphosphate; 7,8-Dihydro-8-oxoguanosine 5'-(tetrahydrogen triphosphate); Purine-6,8(1H,9H)-dione, 2-amino-9-β-D-ribofuranosyl-, 5'-(tetrahydrogen triphosphate); 8-Ketoguanosine 5'-triphosphate. Grade: ≥95% by HPLC. CAS No. 21238-36-8. Molecular formula: C10H16N5O15P3. Mole weight: 539.18. | |
| 8-Oxo-N2-isobutyryl-2'-deoxyguanosine | 8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an exceptional biomedical compound, rendered as a discerning indicator for DNA impairment. It assumes an integral role as a substrate for DNA reparation. Its utilization propels extensive investigation into oxidative species-induced DNA lesions, thereby furnishing profound elucidation into an array of afflictions spanning cancer to neurodegenerative disorders. Synonyms: 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE; 8-HYDROXY-N2-ISOBUTRYL-2/'-DEOXYGUANOSINE; N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-1,7-dihydropurin-2-yl]-2-methylpropanamide; DTXSID40721580; MFCD22373349; N2-Isobutyryl-8-oxo-2'-deoxyguanosine; 2'-Deoxy-N-(2-methylpropanoyl)-8-oxo-7,8-dihydroguanosine; N-(8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grade: ≥ 90%. CAS No. 136859-76-2. Molecular formula: C14H19N5O6. Mole weight: 353.33. | |
| 8-pCPT-2'-O-Me-5'-AMP | 8-pCPT-2'-O-Me-5'-AMP is a potential metabolite of 8-pCPT-2'-O-Me-cAMP, the specific Epac activator. Synonyms: 8-(4-Chlorophenylthio)-2'-O-methyladenosine-5'-O-monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 1187179-94-7. Molecular formula: C17H19ClN5O7PS (free acid). Mole weight: 503.85 (free acid). | |
| 8-pCPT-2'-O-Me-Ado | 8-pCPT-2'-O-Me-Ado is the potential metabolite of 8-pCPT-2'-O-Me-cAMP, a specific Epac activator. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine. Grade: ≥ 98% by HPLC. CAS No. 1187179-96-9. Molecular formula: C17H18ClN6O4S. Mole weight: 423.9. | |
| 8-pCPT-2'-O-Me-cAMP | 8-pCPT-2'-O-Me-cAMP is a PDE-stable activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has high lipophilicity and membrane permeability. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥98% by HPLC. CAS No. 634207-53-7. Molecular formula: C17H16ClN5O6PS · Na. Mole weight: 507.8. | |
| 8-pCPT-2'-O-Me-cAMP-AM | 8-pCPT-2'-O-Me-cAMP-AM is a precursor of 8-pCPT-2'-O-Me-cAMP, the specific Epac agonist. 8-pCPT-2'-O-Me-cAMP is released after the metabolism of 8-pCPT-2'-O-Me-cAMP-AM by esterases. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 1152197-23-3. Molecular formula: C20H21ClN5O8PS. Mole weight: 557.9. | |
| 8-pCPT-2'-O-Me-cGMP | 8-pCPT-2'-O-Me-cGMP is a PDE-stable, high lipophilic and membrane-permeant analogue. It can be used as a control since it has no activated effect on protein kinase G or Epac. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 625112-42-7. Molecular formula: C17H16ClN5O7PS · Na. Mole weight: 523.8. | |
| 8-pCPT-2'-O-Me-cXMP | 8-pCPT-2'-O-Me-cXMP can be used as a control since it has no activated effect on protein kinase G or Epac. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methylxanthosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C17H15ClN4O8PS · Na. Mole weight: 524.8. | |
| 8-pCPT-2'-O-Me-Guo | 8-pCPT-2'-O-Me-Guo is the potential metabolite of the PKG- and Epac-inactive cGMP analogue8-pCPT-2'-O-Me-cGMP. Synonyms: 8- (4- Chlorophenylthio)- 2'- O- methylguanosine. Grade: ≥ 97 % by HPLC. CAS No. 966936-60-6. Molecular formula: C17H18ClN6O6S. Mole weight: 439.9. | |
| 8-pCPT-5'-AMP | 8-pCPT-5'-AMP is a potential metabolite of 8-pCPT-cAMP that inhibits 5'-IMP dehydrogenase. Synonyms: 8-(4-chlorophenylthio)adenosine-5'-O-monophosphate. Grade: ≥ 97 % by HPLC. CAS No. 78710-84-6. Molecular formula: C16H17ClN5O7PS. Mole weight: 489.83. | |
| 8-pCPT-Ado | 8-pCPT-Ado is the potential metabolite of 8-CPT-cAMP. Synonyms: 8- (4- Chlorophenylthio)adenosine. Grade: ≥ 97 % by HPLC. CAS No. 86362-87-0. Molecular formula: C16H16ClN6O4S. Mole weight: 409.9. | |
| 8-pCPT-cGMP | 8-pCPT-cGMP is a selective activator of cGMP-dependent protein kinase type I α and type II, as well as of cGMP-gated ion channels. It has higher membrane permeability and stability towards many phosphodiesterases. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 99% by HPLC. CAS No. 51239-26-0. Molecular formula: C16H14ClN5O7PS · Na. Mole weight: 509.8. | |
| 8-pCPT-cGMP-AM | 8-pCPT-cGMP-AM is a precursor of 8-pCPT-cGMP, the PKG activator. 8-pCPT-cGMP is released after the metabolism of 8-pCPT-cGMP-AM by esterases. Synonyms: 8- (4- Chlorophenylthio)guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. CAS No. 272445-72-4. Molecular formula: C19H19ClN5O9PS. Mole weight: 559.9. | |
| 8-pCPT-Guo | 8-pCPT-Guo, a remarkable agonist with potent effects on the adenosine receptors, specifically targeting adenosine A1R and A3R. Scientific research has found it instrumental in exploring the diverse physiological mechanisms of these receptors. Furthermore, the drug holds immense potential as a treatment option for a range of debilitating conditions such as inflammation, cancer, and neurological disorders. With its multidimensional qualities, 8-pCPT-Guo stands as a compelling player in the medical research landscape. Molecular formula: C16H16ClN6O6S. Mole weight: 426.9. | |
| 8-pCPT-PET-cGMP | 8-pCPT-PET-cGMP is an activator of cyclic GMP-dependent protein kinase as well as an inhibitor of the retinal type cGMP-gated ion channel, thus it can be used for distinction between kinase and ion channel mediated effects. It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Compared to 8-Br-PET-cGMP, 8-pCPT-PET-cGMP is much more lipophilic and membrane-permeant. Synonyms: 8- (4- Chlorophenylthio)- β- phenyl- 1, N2- ethenoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C24H18ClN5O7PS · Na. Mole weight: 609.9. | |
| 8-[φ-450]-cAMP | 8-[φ-450]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Synonyms: 8-[Pharos-450]-adenosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. | |
| 8-[φ-450]-cGMP | 8-[φ-450]-cGMP can be used for studies with intact cells for its excellent lipophilicity and bright green fluorescence. Synonyms: 8-[Pharos-450]-guanosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. | |
| 8-[φ-575]-2'-O-Me-cAMP | 8-[φ-575]-2'-O-Me-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. Synonyms: 8-[Pharos-575]-2'-O-methyladenosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. Mole weight: 731. | |
| 8-[φ-575]-cAMP | 8-[φ-575]-cAMP can be used for studies with intact cells for its excellent lipophilicity and bright red fluorescence. A tiny hypsochromic shift would be developed while binding to PKA. Synonyms: 8-[Pharos-575]-adenosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. | |
| 8-[φ-575]-cGMP | 8-[φ-575]-cGMP is a fuorescent analogue of cGMP, which can be used for studies with intact cells on account of its high lipophilicity and bright red fluorescence. Synonyms: 8-[Pharos-575]-guanosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. Mole weight: 500.4. | |
| 8-pHPT-2'-O-Me-cAMP | 8-pHPT-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It has superior lipophilicity, membrane permeability and PDE stability. Synonyms: 8- (4- Hydroxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate , sodium salt. Grade: ≥ 98% by HPLC. CAS No. 612513-15-2. Molecular formula: C17H17N5O7PS · Na. Mole weight: 489.4. | |
| 8-PIP-cAMP | 8-PIP-cAMP is a selective cAMP analogue with a preference for site A of protein kinase A type I and for site B of type II. Compared to cAMP, it has superior stability and membrane permeability. Synonyms: 8- Piperidinoadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 31357-06-9. Molecular formula: C15H20N6O6P · Na. Mole weight: 434.3. | |
| 8-pMeOPT-2'-O-Me-cAMP | 8-pMeOPT-2'-O-Me-cAMP is a specific activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It is highly lipophilic, membrane-permeant and stable for PDE. Synonyms: 8- (4- Methoxyphenylthio)- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 612513-16-3. Molecular formula: C18H19N5O7PS · Na. Mole weight: 503.4. | |
| 8-pMeOPT-Ado | 8-pMeOPT-Ado is a remarkably potent and preferential activator of adenosine receptors, has established itself as an indispensable tool within the realm of biomedical investigation. This exquisite compound serving as an unrivaled agent for deciphering the intricate involvements of adenosine receptors in multifarious pathological states, encompassing cardiac afflictions, inflammatory cascades is as well as neurodegeneration. Synonyms: 8- (4- Methoxyphenylthio)adenosine. Grade: ≥ 97 % by HPLC. CAS No. 696674-66-8. Molecular formula: C17H19N6O6S. Mole weight: 406.4. | |
| 8-Propyl Etodolac | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-propyl-pyrano[3,4-b]indole-1-acetic Acid. Grade: > 95%. CAS No. 57817-27-3. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
| 8-PT-Ado | 8-PT-Ado, a nucleoside analog employed for biomedical research, holds promise as an antiviral and anticancer drug. Notably, potency against leukemia and herpes simplex virus has been found. Engaging apoptosis induction, DNA synthesis inhibition, and DNA methyltransferase interference, 8-PT-Ado has also been seen to suppress the NF-κB pathway. This pathway is critical for the progression of inflammation and cancer. Synonyms: 8- Phenylthioadenosine. Grade: ≥ 97 % by HPLC. Molecular formula: C16H17N6O4S. Mole weight: 376.4. | |
| 8(S)-HETE | 8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. Synonyms: 8S-hydroxy-5Z,9E,11Z,14Z-eicosatetraenoic acid. Grade: ≥98%. CAS No. 98462-03-4. Molecular formula: C20H32O3. Mole weight: 320.5. | |
| 8S-Isopropyl-3β-hydroxytropanium Bromide | 8S-Isopropyl-3β-hydroxytropanium Bromide is an impurity of Ipratropium Bromide, which is a muscarinic antagonist and a bronchodilator. Synonyms: (1R,3s,5S,8s)-3-Hydroxy-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane Bromide; (1R,3s,5S,8s)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-ol bromide. Molecular formula: C11H22BrNO. Mole weight: 264.21. | |
| 8-Styryl-dG CEP | 8-Styryl-dG CEP, an indispensable compound within the realm of biomedicine, assumes a pivotal role. It facilitates the creation of modified nucleosides and oligonucleotides, thus serving as a fundamental constituent. This compound's distinct structural attributes contribute significantly to drug development and therapies associated with DNA alterations, genetic manipulation, and gene suppression. CAS No. 1101864-12-3. Molecular formula: C51H59N8O7P. Mole weight: 927.04. | |
| 8-TEMPO-aminoadenosine Cyclic 3',5'-Monophosphate | 8-TEMPO-aminoadenosine Cyclic 3',5'-Monophosphate, a spin-labeled cyclic nucleotide used for the mapping of the cAMP site of protein kinase I from rabbit skeletal muscle. Synonyms: 4-[[6-Amino-9-(3,5-O-phosphinico-β-D-ribofuranosyl)-9H-purin-8-yl]amino]-2,2,6,6-tetramethyl-1-piperidinyloxy; 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, 1-Piperidinyloxy Deriv. CAS No. 54606-91-6. Molecular formula: C19H29N7O7P. Mole weight: 498.45. | |
| 8-Thioguanosine | 8-Thioguanosine is a significant compound exhibiting remarkable capabilities in studying viral infections and cancer. By proficiently curtailing viral RNA and DNA replication, it effectively subdues the menace of virulence, while concurrently impeding the enhancement of nucleic acids within cancerous cells. Uses: Adjuvants, immunologic. Synonyms: 8-Mercaptoguanosine; 8-SH-Guo; 2-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-mercapto-1H-purin-6(9H)-one; 7,8-Dihydro-8-thioxoguanosine; 8-Mercapto-7,8-dihydroguanosin; 8-Tio-Guanosine; Guanosine, 8-mercapto-; NSC 79216; SQ 12760. Grade: ≥97% by HPLC. CAS No. 26001-38-7. Molecular formula: C10H13N5O5S. Mole weight: 315.31. | |
| 8-Trifluoromethyl-ADP | 8-Trifluoromethyl-ADP is a nucleoside diphosphate that plays a crucial role in energy metabolism. It serves as a substrate for enzymes involved in the synthesis of ATP, which is a key currency of cellular energy. Additionally, it is also used in research to study the regulation of various ion channels and transporters, as well as to investigate signal transduction pathways implicated in a variety of diseases such as cancer and neurological disorders. Synonyms: 8-Trifluoromethyl-adenosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C11H14N5O10P2F3 (free acid). Mole weight: 495.20 (free acid). | |
| 8-(trifluoromethyl)-Guanosine | 8-(Trifluoromethyl)-Guanosine is a potent and selective antiviral compound employed in the biomedical sector, used in research of viral infections, specifically RNA viruses like hepatitis C and Zika. Synonyms: Guanosine, 8-(trifluoromethyl)-. CAS No. 36799-14-1. Molecular formula: C11H12F3N5O5. Mole weight: 351.24. | |
| 8-Vinyl-dA CEP | 8-Vinyl-dA CEP is a cutting-edge biomedical compound, acting as a fundamental building block for custom nucleotides and oligonucleotides. CAS No. 851228-42-7. Molecular formula: C45H55N8O6P. Mole weight: 834.94. | |
| 9,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin Hydrochloride | 9,10-Anhydro-8-desacetyl-8-carboxy Daunorubicin Hydrochloride is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (S)-4-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,12-dihydroxy-7-methoxy-6,11-dioxo-3,4,6,11-tetrahydrotetracene-2-carboxylic acid hydrochloride. Grade: >85%. Molecular formula: C26H26ClNO10. Mole weight: 547.94. | |
| 9,10-Anhydro-8-desacetyl-8-carboxy Desamino-N-trifluoroacetamide Daunorubicin | 9,10-Anhydro-8-desacetyl-8-carboxy Desamino-N-trifluoroacetamide Daunorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Methyl (4S)-5,12-dihydroxy-7-methoxy-6,11-dioxo-4-({2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl}oxy)-3,4,6,11-tetrahydro-2-tetracenecarboxylate; 2-Naphthacenecarboxylic acid, 3,4,6,11-tetrahydro-5,12-dihydroxy-7-methoxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, methyl ester, (4S)-. Molecular formula: C29H26F3NO11. Mole weight: 621.52. | |
| 9,10-Anhydro-8-desacetyl-8-carboxy Doxorubicin N-Trifluoroacetamide | 9,10-Anhydro-8-desacetyl-8-carboxy Doxorubicin N-Trifluoroacetamide is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: N-((2S,3S,4S,6R)-6-(((S)-5,12-dihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)-2,2,2-trifluoroacetamide; 5,12-Naphthacenedione, 9,10-dihydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (S)-. CAS No. 68168-15-0. Molecular formula: C29H26F3NO11. Mole weight: 621.51. | |
| 9,10-Anhydro-8-desacetyl-N-(trifluoroacetyl)daunorubicin Methyl Ester | 9,10-Anhydro-8-desacetyl-N-(trifluoroacetyl)daunorubicin Methyl Ester is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (S)-5,12-dihydroxy-4-(((2R,4S,5S,6S)-5-hydroxy-6-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-6,11-dioxo-3,4,6,11-tetrahydrotetracene-2-carboxylic acid. Molecular formula: C28H24F3NO11. Mole weight: 607.49. | |
| 9,10-Anhydro doxorubicin | 9,10-Anhydro doxorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity 8; 9,10-Anhydroadriamycin; (1S)-3-Glycoloyl-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,6,11-tetrahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 9,10-Anhydrodoxorubicin; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-9,10-dihydro-6,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (10S)-; (S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-9,10-dihydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione. Grade: ≥95%. CAS No. 80996-23-2. Molecular formula: C27H27NO10. Mole weight: 525.50. | |
| 9,10-Anhydro Doxorubicin TFA salt | 9,10-Anhydro Doxorubicin TFA salt is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 9,10-Anhydroadriamycin TFA salt; 9,10-Anhydrodoxorubicin TFA salt; Doxorubicin Impurity 8 TFA salt; (1S)-3-Glycoloyl-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,6,11-tetrahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside TFA salt; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-9,10-dihydro-6,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (10S)-, TFA salt (1:1); (S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-9,10-dihydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione TFA salt. Molecular formula: C29H28F3NO12. Mole weight: 639.53. | |
| 9,10-Dehydro Folitixorin-(phenylene-d4) Chloride | 9,10-Dehydrofluorothioxanthene-(phenylene-d4) chloride is an isotopically labelled intermediate for the preparation of calcium folinate. Synonyms: 3-Amino-8-[4-[[[(1S)-1,3-dicarboxypropyl]amino]carbonyl]phenyl]-2,5,6,6a,7,8-hexahydro-1-oxo-1H-imidazo[1,5-f]pteridin-10-ium-d4 Chloride. Molecular formula: C20H20D4ClN7O6. Mole weight: 497.93. | |
| 9,10-Dimethoxy-pterocarpane-3-O-b-D-glucoside | 9,10-Dimethoxy-pterocarpane-3-O-b-D-glucoside. | |
| 9,11-Dehydro 17(α)-Dihydroequilin Dibenzoate | 9,11-Dehydro 17(α)-Dihydroequilin Dibenzoate is a metabolite of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Synonyms: (17α)-Estra-1(10),2,4,6,8-pentaene-3,17-diyl dibenzoate; Estra-1(10),2,4,6,8-pentaene-3,17-diol, dibenzoate, (17α)-. Molecular formula: C32H28O4. Mole weight: 476.56. | |
| 9,11-Dehydro Ethylnyl Estradiol (Impurity B) | An impurity of Estradiol. Estradiol? is the major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Synonyms: (17α)-19-Norpregna-1,3,5(10),9(11)-tetraen-20-yne-3,17-diol; 19-Nor-17α-pregna-1,3,5(10),9(11)-tetraen-20-yne-3,17-diol; USP Ethinyl Estradiol Related Compound B; Ethinyl Estradiol Impurity B (EP). Grade: > 95%. CAS No. 1231-96-5. Molecular formula: C20H22O2. Mole weight: 294.40. | |
| 9,11-Dehydro Flunisolide | An impurity of Flunisolide. Flunisolide is a corticosteroid used primarily for its anti-inflammatory properties, particularly in the treatment of respiratory conditions such as asthma and allergic rhinitis. It is administered via inhalation and works by reducing inflammation in the airways. Synonyms: Pregna-1,4,9(11)-triene-3,20-dione, 6α-fluoro-16α,17,21-trihydroxy-, cyclic 16,17-acetal with acetone; 6α-Fluoro-21-hydroxy-16α,17-(isopropylidenedioxy)pregna-1,4,9(11)-triene-3,20-dione; (6α,16α)-6-Fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-pregna-1,4,9(11)-triene-3,20-dione. Grade: ≥95%. CAS No. 21365-80-0. Molecular formula: C24H29FO5. Mole weight: 416.48. | |
| 9,12-Octadecadiynoic acid | 9,12-Octadecadiynoic acid is an inhibitor of both COX and lipoxygenase. Synonyms: Ro 3-1314; 9a-12a-Octadecadiynoic acid. Grade: ≥98%. CAS No. 2012-14-8. Molecular formula: C18H28O2. Mole weight: 276.4. | |
| 9,13-Di-cis-retinoic Acid | 9,13-Di-cis-retinoic Acid is a metabolite of 9-cis Retinoic Acid that induces liver fibrosis through activating transforming growth factor-β. Synonyms: (9-cis,13-cis)-Retinoic Acid; (2Z,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid; Isotretinoin EP Impurity B. CAS No. 5352-74-9. Molecular formula: C20H28O2. Mole weight: 300.44. | |
| 9,14-Deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxorapamycin | It can be prepared as an immunosuppressant. Synonyms: Rapamycin, 9,14-deepoxy-15-deoxo-14-deoxy-9,15-epoxy-15-hydroxy-14-oxo-. CAS No. 150821-39-9. Molecular formula: C51H79NO13. Mole weight: 914.17. | |
| 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine | 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a vital compound exhibiting promising anti-viral properties and employed in the research of various viral diseases. With its unique chemical structure, It acts effectively against specific DNA and RNA viruses. Synonyms: 2'-C-Methyl-2',3',5'-tri-O-benzoyl-beta-D-6-methylpurine riboside; 6-Methyl-9-(2-C-methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)purine. Grade: ≥95%. CAS No. 2095417-61-9. Molecular formula: C33H28N4O7. Mole weight: 592.60. | |
| 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine | 9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine, an essential constituent utilized in the advancement of antiviral treatments, requires thorough investigation due to its significant implications in restraining the duplication of viral DNA. Hence, owing to its unparalleled configuration and biochemical characteristics, this compound exhibits substantial promise as a potential intervention against diverse viral infections. Moreover, its distinctive attributes may facilitate the targeting of drug-resistant variants, rendering it highly effective in combating a spectrum of viral maladies. Synonyms: 9-(2-C-Methyl-2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)purine; 9-(2',3',5'-Tri-O-benzoyl-2'C-methyl-b-D-ribofuranosyl)purine. Grade: ≥95%. CAS No. 2095417-45-9. Molecular formula: C32H26N4O7. Mole weight: 578.57. | |
| 9-(2',3',5'-tri-O-benzoyl-5'-(R)-C-Methyl-b-D-ribofuranosyl)-6-chloropurine | 9-(2',3',5'-tri-O-benzoyl-5'-(R)-C-Methyl-b-D-ribofuranosyl)-6-chloropurine. | |
| 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine | 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine, commonly known as TBA, is an immensely powerful antiviral compound that displays inhibitory efficacy in research of a wide array of malignancies such as leukemia, lymphoma and solid tumors. By obstructing the propagation of viral DNA and RNA, this pharmacological compound successfully impedes the proliferation and dissemination of malignant cells. Synonyms: 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl) adenine. CAS No. 3257-73-6. Molecular formula: C31H31N5O4. Mole weight: 537.61. | |
| 9-(2,5-Dioxo-L-3-amino-1-pyrrolidineacetic acid)-10-deglycine-daptomycin | 9-(2,5-Dioxo-L-3-amino-1-pyrrolidineacetic acid)-10-deglycine-daptomycin is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-Succinimidylglycyl-D-serylthreo-3-Methyl-L-glutamyl-3-Anthraniloyl-L-alanine (ε1-lactone); Daptomycin dehydrate; Daptomycin Impurity 2; Benzenebutanoic acid, N-(1-oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-(3S)-3-amino-2,5-dioxo-1-pyrrolidineacetyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-, (12→4)-lactone, (αS)-; Daptomycin, 9-(2,5-dioxo-L-3-amino-1-pyrrolidineacetic acid)-10-deglycine-; CB 130952; LY 178480; Anhydro-Daptomycin. Grade: >95%. CAS No. 121869-35-0. Molecular formula: C72H99N17O25. Mole weight: 1602.66. | |
| 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine | 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a bioactive compound used in biomedicine to treat various diseases. It exhibits potent antiviral activity against certain types of viruses by inhibiting their replication. Additionally, it has been investigated as a potential therapeutic agent for certain cancers and autoimmune diseases due to its ability to modulate immune responses. Synonyms: 2'-C-Methyl-beta-D-6-methylpurine riboside; 6-Methyl-9-(2-C-methyl-beta-D-ribofuranosyl)purine. Grade: ≥95%. CAS No. 2095417-06-2. Molecular formula: C12H16N4O4. Mole weight: 280.28. | |
| 9-(2-C-Methyl-b-D-ribofuranosyl)purine | 9-(2-C-Methyl-b-D-ribofuranosyl)purine is a formidable nucleoside analogrenowned for its unwavering antiviral prowess. This exceptional compound operates as a potent nucleoside reverse transcriptase inhibitor, skillfully impeding viral replication via the artful blockade of the reverse transcriptase enzyme. Synonyms: 9-(2-C-Methyl-β-D-ribofuranosyl)purine; 9H-Purine, 9-(2-C-methyl-beta-D-ribofuranosyl)-; (2R,3R,4R,5R)-5-(Hydroxymethyl)-3-methyl-2-(9H-purin-9-yl)tetrahydrofuran-3,4-diol; 9-(2-C-Methyl-β-D-ribofuranosyl)-9H-purine. Grade: ≥95%. CAS No. 690269-86-4. Molecular formula: C11H14N4O4. Mole weight: 266.25. | |
| 9-(2'-Deoxy-2'-fluoro-a-D-arabinofuranosyl)-9H-purin-6-amine | 9-(2'-Deoxy-2'-fluoro-α-D-arabinofuranosyl)-9H-purin-6-amine, a remarkable compound renowned for its potent antiviral properties, is extensively utilized within the esteemed biomedical sector. This exceptional therapeutic agent plays a pivotal role in combatting a plethora of viral infections triggered by the herpes simplex, varicella-zoster, and Epstein-Barr viruses. By impeding the replication of viral DNA, it actively thwarts the proliferation and recurrence of these notorious viral maladies. Synonyms: (2R,3R,4S,5S)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 20187-82-0. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxantine | 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)hypoxanthine, a remarkable antiviral agent and immunosuppressant, exhibits significant potential in combating viral infections such as herpes simplex virus and cytomegalovirus. A potent mechanism arises from its ability to impede viral DNA replication through chain termination, thereby obstructing viral DNA elongation. Synonyms: 2'-FANA-I. Grade: 97%. Molecular formula: C10H11FN4O4. Mole weight: 270.22. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine | 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-2-fluoroadenine, an extraordinary antiviral compound, exhibits immense potential in the biomedical field for combating viral infections induced by DNA viruses. Its exceptional efficacy stems from its ability to disrupt viral DNA synthesis, thereby impeding viral replication. This nucleoside analogue has demonstrated remarkable effectiveness against a multitude of viruses, including herpes simplex virus type 1 (HSV-1) and 2 (HSV-2), varicella-zoster virus (VZV), and Epstein-Barr virus (EBV). Synonyms: 2'-Deoxy-2'-fluoro-2-fluoroadenosine. Grade: 95%. CAS No. 147048-53-1. Molecular formula: C10H11F2N5O3. Mole weight: 287.23. | |
| 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine | 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine, an esteemed biomedical compound, stands as a paramount weapon in combatting egregious viral entities. Harnessing its remarkable antiviral potential, this compound seamlessly infiltrates viral life cycles by selectively impeding the replication of viral enzymes. Synonyms: 2'-Deoxy-2'-fluoroisoguanosine. Grade: 98%. Molecular formula: C10H12FN5O4. Mole weight: 285.24. | |
| 9-(2-Deoxy-2-fluoro-b-D-xylofuranosyl)-9H-purin-6-amine | 9-(2-Deoxy-2-fluoro-b-D-xylofuranosyl)-9H-purin-6-amine, commonly known as DFXY, is a remarkable antiviral agent employed for combatting specific viral infections, including hepatitis B and C. With its precise mechanism of action targeting the viral polymerase enzyme, DFXY displays remarkable effectiveness in hindering viral replication. Synonyms: (2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol; 9H-Purin-6-amine, 9-(2-deoxy-2-fluoro-β-D-xylofuranosyl)-; 9-(2-Deoxy-2-fluoro-β-D-xylofuranosyl)-9H-purin-6-amine; 2'-Fluoro-2'-deoxy-β-D-xylo-adenosine. Grade: ≥97% by HPLC. CAS No. 123334-75-8. Molecular formula: C10H12FN5O3. Mole weight: 269.23. | |
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