BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 9-cis-Retinoic Acid Methyl Ester | 9-cis-Retinoic Acid Methyl Ester is a derivative of Vitamin A. Synonyms: 9-cis-Methyl Retinoate; Retinoic acid, methyl ester, 9-cis-. Grade: 95%. CAS No. 58526-50-4. Molecular formula: C21H30O2. Mole weight: 314.46. |  |
| 9-cis Retinol | A metabolite of Vitamin A. Synonyms: 9-cis-Retinol; 9-cis-Vitamin A Alcohol. Grade: > 95%. CAS No. 22737-97-9. Molecular formula: C20H30O. Mole weight: 286.46. | |
| 9-cis Retinol Acetate | A retinal derivative for treatment of visual disorders. Uses: Adjuvants, immunologic. Synonyms: 9-cis-Retinyl Acetate; 9-cis-Vitamin A Acetate; 9-cis-Vitamin A1 Acetate. Grade: > 95%. CAS No. 29584-22-3. Molecular formula: C22H32O2. Mole weight: 328.5. | |
| 9-cis Retinyl Linoleate | 9-cis-Retinyl Linoleate is a fatty acid ester of Retinol isomer. Synonyms: 9-cis-Retinol Linoleate; (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl (9Z,12Z)-octadeca-9,12-dienoate; (9-cis)-[(9Z,12Z)-9,12-Octadecadienoyl]retinol. Grade: ≥95%. CAS No. 79299-81-3. Molecular formula: C38H60O2. Mole weight: 548.88. | |
| 9-cis-Retinyl Oleate | 9-cis-Retinyl Oleate is a biomedical product used in the research of age-related macular degeneration (AMD). It is a derivative of vitamin A that helps improve vision and retinal function. Uses: A fatty acid ester of retinol isomer, found mainly in the retina. Synonyms: [9-cis,15(Z)]-Retinol 9-Octadecenoate; Retinol, 15-(9Z)-9-octadecenoate, 9-cis-; (9-cis)-[(9Z)-9-Octadecenoyl]retinol. Grade: 95%. CAS No. 79433-57-1. Molecular formula: C38H62O2. Mole weight: 550.90. | |
| 9-cis-Retinyl Stearate | 9-cis-Retinyl Stearate is a biomedical compound used in the research of various dermatological conditions, including acne, psoriasis and photoaging. It is a derivative of vitamin A, specifically retinol, that exhibits potent antioxidant and anti-inflammatory properties. Uses: A fatty acid ester of retinol isomer, found mainly in the retina. Synonyms: 9-cis-Retinol Octadecanoate; Retinol, octadecanoate, 9-cis-; (9-cis)-Stearoylretinol; Retinol, (1-oxooctadecyl)-, (9-cis)-; (9-cis)-Octadecanoylretinol. Grade: 95%. CAS No. 79299-77-7. Molecular formula: C38H64O2. Mole weight: 552.91. | |
| 9-Deaza-2'-deoxyguanosine | 9-Deaza-2'-deoxyguanosine is a renowned compound in the biomedical sector, exhibiting profound versatility as a potent antiviral and antitumor compound. By virtue of its remarkable attributes, this compound showcases an exceptional potential for studying the detrimental consequences of viral infections and malignant neoplasms. Synonyms: 9-Deaza-2'-deoxyguanosine(2-amino-7-(beta-d-2-deoxyribofuranosyl)pyrrolo[3,2-d]pyrimidin-4-one). Grade: ≥ 97%. CAS No. 224946-77-4. Molecular formula: C11H14N4O4. Mole weight: 266.26. | |
| 9-Deazaguanosine | 9-Deazaguanosine is an antiviral compound, impeding viral replication and invigorating immune responses. Grade: ≥ 97%. CAS No. 102731-45-3. Molecular formula: C11H14N4O5. Mole weight: 282.26. | |
| 9-Demethyl FR-901235 | 9-demethyl FR-901235 is a polyketide fungal metabolite produced by the strain of Penicillium. Synonyms: FR-901235, 9-Demethyl; (+)-2,4,6,9-tetrahydroxy-7-methyl-2-(2-oxopropyl)-1H-phenalene-1,3(2H)-dione. Grade: >95% by HPLC. CAS No. 1029520-85-1. Molecular formula: C17H14O7. Mole weight: 330.29. | |
| 9-Deoxo-9a-aza-9a-homo 4'-Keto Erythromycin A | 9-Deoxo-9a-aza-9a-homo 4'-Keto Erythromycin A is an intermediate in the synthesis of erythromycin A, an antibiotic used to treat respiratory diseases in cattle and pigs. Synonyms: 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranos-4-ulos-1-yl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-; (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranos-4-ulos-1-yl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. CAS No. 270583-32-9. Molecular formula: C37H68N2O12. Mole weight: 732.94. | |
| 9-Deoxydoxorubicin Hydrochloride | 9-Deoxydoxorubicin is an anthracycline antibiotic used in the treatment off cancer cells. Synonyms: (8R,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-12-naphthacenedione Hydrochloride; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8R-trans)-; 9-Dehydroxydoxorubicin Hydrochloride; NSC 298225; (1S,3R)-3-Glycoloyl-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1). Grade: ≥95%. CAS No. 73027-02-8. Molecular formula: C27H30ClNO10. Mole weight: 563.98. | |
| 9-Desaminoethyl Pixantrone | 9-Desaminoethyl Pixantrone is a derivative of Pixantrone, which is a synthetic and noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Synonyms: 9-amino-6-((2-aminoethyl)amino)benzo[g]isoquinoline-5,10-dione; Benz[g]isoquinoline-5,10-dione, 9-amino-6-[(2-aminoethyl)amino]-. Grade: ≥95%. Molecular formula: C15H14N4O2. Mole weight: 282.30. | |
| 9-Deschloro Mometasone | An impurity of Mometasone furoate, which is a topical corticosteroid used as an anti-inflammatory agent. Molecular formula: C22H27ClO4. Mole weight: 390.90. | |
| 9-Desmethyl-alpha-Dihydro-Tetrabenazine | 9-Desmethyl-alpha-Dihydro-Tetrabenazine is one of Tetrabenazine derivatives. Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders. Synonyms: (+)-9-O-Desmethyl-a-dihydrotetrabenazine; 1H-Naphtho[2,3-c]pyran-3-aceticacid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R,3S); Desoxyfrenolicin; (2R,3R,11bR)-9-O-desmethyldihydrotetrabenazine; (+)-deoxyfrenolicin; 1H-Naphtho(2,3-c)pyran-3-acetic acid,3,4,5,10-tetrahydro-9-hydroxy-5,10-dioxo-1-propyl-,(1R-trans); 9-o-Desmethyl-alpha-dihydrotetrabenazine; 3-isobutyl-10-methoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinoline-2,9-diol. Grade: ≥95%. CAS No. 1065193-59-0. Molecular formula: C18H27NO3. Mole weight: 305.41. | |
| 9-Desmethyl-beta-Dihydro Tetrabenazine | 9-Desmethyl-beta-Dihydro Tetrabenazine is an impurity of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: (2S,3R,11bR)-3-Isobutyl-10-methoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline-2,9-diol; 9-o-Desmethyl-beta-htbz; 9-o-Desmethyl-beta-dihydrotetrabenazine; 2H-Benzo(a)quinolizine-2,9-diol, 1,3,4,6,7,11b-hexahydro-10-methoxy-3-(2-methylpropyl)-, (2S,3R,11bR)-. CAS No. 1214267-68-1. Molecular formula: C18H27NO3. Mole weight: 305.41. | |
| 9-Desmethyl Tetrabenazine | 9-Desmethyl Tetrabenazine is a derivative of Tetrabenazine, which is a VMAT inhibitor used in the treatment of hyperkinetic movement disorder. Synonyms: 1,3,4,6,7,11b-Hexahydro-9-hydroxy-10-methoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one; 9-Hydroxy-3-isobutyl-10-methoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one; Desmethyl tetrabenazine; 9-Hydroxy-3-isobutyl-10-methoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one. Grade: ≥95%. CAS No. 149183-89-1. Molecular formula: C18H25NO3. Mole weight: 303.40. | |
| 9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 | 9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 is the major DNA adduct formed by the liver carcinogen aflatoxin B1. Synonyms: 2-Amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6,9-dihydro-7-(1,2,3,6a,8,9,9a,11-octahydro-9-hydroxy-4-methoxy-1,11-dioxocyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-8-yl)-6-oxo-1H-purinium; AFB1-N7-Gua; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran, 1H-purinium deriv. CAS No. 64585-66-6. Molecular formula: C27H26N5O11. Mole weight: 596.52. | |
| 9-Epimitomycin B | 9-Epimitomycin B is an intermediate in the formation of mitomycin B, an antitumor antibiotic. Synonyms: Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-6-methoxy-, (1aS-(1a-alpha,8-beta,8a-alpha,8b-alpha))-; 9-epi-Mitomycin B. Grade: 95%. CAS No. 13164-90-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. | |
| 9-Ethylguanine | 9-Ethylguanine, a chemical compound utilized by the biomedical industry to probe the mechanisms of DNA repair, may also serve as a biomarker for carcinogenic effects caused by substances like tobacco smoke. Studies have indicated its potential involvement in the pathogenesis of bladder cancer and other malignancies. Synonyms: 2-Amino-9-ethyl-1,9-dihydro-6H-purin-6-one; NSC 22755; 2-amino-9-ethyl-1H-purin-6(9H)-one; 2-amino-9-ethyl-3H-purin-6-one; 2-Amino-9-ethyl-6-hydroxypurine; 6-Amino-9-ethyl-2-hydroxypurine; NSC 22755. Grade: ≥98% by HPLC. CAS No. 879-08-3. Molecular formula: C7H9N5O. Mole weight: 179.18. | |
| 9H-?Purin-?2-?amine, 9-?[2-?O-?acetyl-?3-?azido-?3-?deoxy-?5-?O-?(4-?methylbenzoyl)?-?β-?D-?ribofuranosyl]?-?6-?chloro-?N-?[(4-?methoxyphenyl)?diphenylmethyl]?- | 9H-Purin-2-amine, 9-[2-O-acetyl-3-azido-3-deoxy-5-O-(4-methylbenzoyl)-β-D-ribofuranosyl]-6-chloro-N-[(4-methoxyphenyl)diphenylmethyl] is a novel biomedical compound utilized in the research of various viral infections and certain types of cancer. It exhibits potent antiviral and anticancer properties, targeting specific pathways involved in viral replication and cancer progression. CAS No. 2299278-18-3. Molecular formula: C40H35ClN8O6. Mole weight: 759.21. | |
| 9-Hydroxy Benzopyrene | A metabolite of Benzopyrene.Benzopyrene is a carcinogenic component of tobacco smoke implicated in lung cancer. Synonyms: Benzo[a]pyren-9-ol; 9-Hydroxybenzo[a]pyrene. Grade: > 95%. CAS No. 17573-21-6. Molecular formula: C20H12O. Mole weight: 268.32. | |
| 9-Hydroxyellipticine hydrochloride | 9-Hydroxyellipticine hydrochloride is a potent and selective topoisomerase II and RyR inhibitor with IC50s of 1.6 and 1.2 μM in Hela S-3 and 293T cells, respectively. It has antitumor, antioxidant and catecholamine-releasing activities. Synonyms: NSC264136; 6H-Pyrido(4,3-b)carbazol-9-ol, 5,11-dimethyl-, monohydrochloride; 6H-Pyrido[4,3-b]carbazol-9-ol, 5,11-dimethyl-, hydrochloride (1:1). Grade: >98%. CAS No. 52238-35-4. Molecular formula: C17H15ClN2O. Mole weight: 298.77. | |
| 9-Hydroxymethyl-10-carbamoylacridan | 9-Hydroxymethyl-10-carbamoylacridan is an impurity of Carbamazepine which is used in treatment of pain associated with trigeminal neuralgia. Uses: Carbamazepine. Synonyms: 9-(Hydroxymethyl)-10(9H)-acridinecarboxamide. CAS No. 68011-71-2. Molecular formula: C15H14N2O2. Mole weight: 254.28. | |
| 9-Hydroxy Prednisolone | 9-Hydroxy Prednisolone is an impurity of Prednisolone, which is a synthetic glucocorticoid, a derivative of cortisol, and can be used to treat a variety of inflammatory and auto-immune conditions. Synonyms: Prednisolone Impurity. Grade: >95%. Molecular formula: C21H28O5. Mole weight: 360.45. | |
| 9-ing-41 | 9-ING-41 is a potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3). 9-ING-41 induces cell cycle arrest, autophagy and apoptosis in bladder cancer cells. Synonyms: elraglusib. CAS No. 1034895-42-5. Molecular formula: C22H13FN2O5. Mole weight: 404.35. | |
| 9-Keto Risperidone | An impurity of Paliperidone which is an active metabolite of RISPERIDONE and used as a second generation (atypical) antipsychotic agent. Synonyms: Paliperidone ketone; 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-7,8-dihydro-2-methyl-4H-pyrido[1,2-a]pyrimidine-4,9(6H)-dione. Grade: > 95%. CAS No. 1189516-65-1. Molecular formula: C23H25FN4O3. Mole weight: 424.48. | |
| 9-L-β-Aspartic acid-daptomycin | 9-L-β-Aspartic acid-daptomycin is an impurity of Daptomycin, which is a lipopeptide antibiotic used to treat systemic infections and life-threatening infections caused by gram-positive organisms. Synonyms: Daptomycn β-Isomer; Daptomycin, 9-L-β-aspartic acid-; CB 131010; LY 213846; N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithyl-L-α-aspartyl-D-alanyl-L-β-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-(αS)-α,2-diamino-γ-oxobenzenebutanoic acid (13→4)-lactone; N-decanoyl-L-tryptophyl-D-asparginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-β-aspartylglycyl-D-serylthreo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine (ε1-lactone). Grade: ≥95%. CAS No. 123180-72-3. Molecular formula: C72H101N17O26. Mole weight: 1620.67. | |
| 9-methoxy-7-ethylcamptothecin | 9-methoxy-7-ethylcamptothecin is an impurity of irinotecan and camptothecin analogues. It is also an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: (S)-4,11-Diethyl-4-hydroxy-10-methoxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione; Camptothecin Impurity 17. CAS No. 200619-39-2. Molecular formula: C23H22N2O5. Mole weight: 406.43. | |
| 9-Methyl Acridine | An derivative of Acridine. Synonyms: 9-Methylacridine; 611-64-3; ACRIDINE, 9-METHYL-; 5-Methylacridine; 9-Methylakridin; 1F3Q4U9UIS; NSC-1234; MFCD00143523; 9-methyl acridine; 9-Methylakridin [Czech]; 5-Methylacridine (European); 88813-63-2; NSC 1234; EINECS 210-272-4; UNII-1F3Q4U9UIS; BRN 0133084; 9-Methylacridin; Carbamazepine Imp. B (EP); 9-Methylacridine; Carbamazepine Impurity B; 9-Methyl-acridine; SCHEMBL50940; 5-20-08-00253 (Beilstein Handbook Reference); MLS001178347; CHEMBL1883643; FLDRLXJNISEWNZ-UHFFFAOYSA-; DTXSID60862287; NSC1234; WLN: T C666 BNJ I1; HMS2795J23; 9-METHYLACRIDINE [USP-RS]; AMY41959; CARBAMAZEPINE IMPURITY B [IP]; AKOS005208327; CS-W015767; DS-7478; SMR000475881; SY051181; FT-0762093; M1237; CARBAMAZEPINE IMPURITY B [EP IMPURITY]; EN300-235746; F30121; AE-641/02557061; J-640193; Q27252344; F2174-0001; 9-Methylacridine, United States Pharmacopeia (USP) Reference Standard; InChI=1/C14H11N/c1-10-11-6-2-4-8-13(11)15-14-9-5-3-7-12(10)14/h2-9H,1H3. Grade: > 95%. CAS No. 611-64-3. Molecular formula: C14H11N. Mole weight: 193.25. | |
| 9-Methyladenine | A receptor adenine derivative binding membrane brain animal cell line. Synonyms: N9-Methyladenine; 6-Amino-9-methylpurine; 9-Methyl Adenine; 9-Methyl-9H-purin-6-amine; NSC 7843; 9-Methyl-9H-adenine; 9-methyl-9H-purin-6-ylamine. Grade: ≥95% by HPLC. CAS No. 700-00-5. Molecular formula: C6H7N5. Mole weight: 149.15. | |
| 9-Monodemethyl Minocycline | 9-Monodemethyl Minocycline is a tetracycline derivative used in antibiotic pharmaceutical compositions. Grade: > 95%. CAS No. 4769-39-5. Molecular formula: C22H25N3O7. Mole weight: 443.45. | |
| 9-Nitrooleate | 9-Nitrooleate is an activator of PPARγ. OA-NO2 is found in human plasma as the free acid and esterified in phospholipids at concentrations of 619 ± 52 nM and 302 ± 369 nM, respectively. OA-NO2 activates PPARγ approximately 7-fold at a concentration of 1 μM and effectively promotes differentiation 3T3-L1 preadipocytes to adipocytes at 3 μM. Synonyms: 9-nitro-9E-octadecenoic acid; 9-Nitro Oleic Acid; 9-Nitrooleic acid; 9-nitro-9-trans-Octadecenoic acid. Grade: ≥98%. CAS No. 875685-44-2. Molecular formula: C18H33NO4. Mole weight: 327.46. | |
| 9-(N-Methyl-L-valine)cyclosporin A | 9-(N-methyl-L-valine)cyclosporin A is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane, cyclic peptide deriv.; N-Methyl-valyl-4-cyclosporin A; N-Methyl-Val-4-CsA; SDZ 220-384; cyclo[Abu-Sar-N(Me)Val-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; cyclo[((2S)-2-aminobutyryl)-sarcosyl-N-methyl-L-valyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-N-methyl-(4R)-4-[(E)-but-2-enyl]-4-methyl-L-threonyl]; Cyclosporin A, 9-(N-methyl-L-valine)-. CAS No. 156047-28-8. Molecular formula: C61H109N11O12. Mole weight: 1188.58. | |
| 9-Norketo FK-506 | 9-Norketo FK-506 is an impurity of FK-506, a novel immunosuppressant isolated from the fermentation broth of Streptomyces tsukubaenis. Grade: 95%. CAS No. 123719-19-7. Molecular formula: C43H69NO11. Mole weight: 776.01. | |
| 9-O-(6-O-Malonyl-β-D-glucopyranosyl) Alternariol | 9-O-(6-O-Malonyl-β-D-glucopyranosyl) Alternariol is a derivative of Alternariol which is an alternaria mycotoxin and genotoxin, found in common edible crops. Alternariol inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks. Alternariol 3- Sulfate Ammonium Salt is currently suspected of being formed during metabolism in contaminated plants. Synonyms: 9-O-(6-O-Malonyl-beta-D-glucopyranosyl) alternariol; 1779520-66-9. CAS No. 1779520-66-9. Molecular formula: C23H22O13. Mole weight: 506.41. | |
| 9-Oxo Epinastine HBr | An impurity of Epinastine. Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H3 receptors and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Synonyms: 3-Amino-1,13b-dihydro-9H-dibenz[c,f]imidazo[1,5-a]azepin-9-one. Grade: > 95%. CAS No. 745761-19-7. Molecular formula: C16H13N3O. HBr. Mole weight: 263.30 80.91. | |
| 9-Phenanthrol | 9-Phenanthrol, a cell permeable hydroxytricyclic derivative, functions as a selective inhibitor of TRPM4 (IC50 = 20 μM in HEK293 cells) and exhibits no effect on CFTR or TRPM5 (at 0.25 and 1 mM respectively). 9-Phenanthrol was used to investigate C K-edge and O K-edge near-edge X-ray absorption fine structure (NEXAFS) spectra of single-wall carbon nanotubes. Uses: Protein kinase inhibitors. Synonyms: phenanthren-9-ol. CAS No. 484-17-3. Molecular formula: C14H10O. Mole weight: 194.23. | |
| 9-Piperazine Levofloxacin | An impurity of Levofloxacin, which is as efficacious as or more efficacious than that with ciprofloxacin in systemic as well as pyelonephritis infections in mice. Synonyms: Levofloxacin EP Impurity I; (-)-(S)-10-Fluoro-2,3-dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid. Grade: > 95%. CAS No. 178912-62-4. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| 9-Piperazino Ofloxacin | An impurity of Ofloxacin, which is a synthetic broad-spectrum antimicrobial agent. Synonyms: 10-Fluoro-2,3-dihydro-3-methyl-9-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid. Grade: > 95%. CAS No. 197291-75-1. Molecular formula: C18H20FN3O4. Mole weight: 361.38. | |
| 9(R)-HETE | 9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE. Synonyms: 9R-hydroxy-5Z,7E,11Z,14Z-eicosatetraenoic acid. Grade: ≥98%. CAS No. 107656-14-4. Molecular formula: C20H32O3. Mole weight: 320.5. | |
| 9-Ribofuranosyl-9H-Purine-6-thiol | 9-Ribofuranosyl-9H-Purine-6-thiol, utilized as an antiviral therapy to hinder viral replication, has been demonstrated to treat viral infections including, but not limited to, Hepatitis B and HIV. Its selectivity enables the targeted impact on infected CD4 T-helper cells, subsequently leading to a decrease of the viral load while simultaneously heightening the CD4 cell count. Synonyms: 9H-Purine-6-thiol, 9-ribofuranosyl-; 6H-Purine-6-thione, 3,9-dihydro-9-D-ribofuranosyl-; 6-Mercapto-9β-D-ribofuranosyl-9H-purine; 9-(D-Ribofuranosyl)-3,9-dihydro-6H-purine-6-thione; 9-(D-ribofuranosyl)-9H-purine-6-thiol. Grade: ≥97% by HPLC. CAS No. 4988-64-1. Molecular formula: C10H12N4O4S. Mole weight: 284.29. | |
| 9(Z),11(E),13(E)-Octadecatrienoic acid | 9(Z),11(E),13(E)-Octadecatrienoic acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. Synonyms: α-Eleostearic acid; α-ESA; LAF 237; alpha-Eleostearic acid. Grade: ≥95%. CAS No. 506-23-0. Molecular formula: C18H30O2. Mole weight: 278.4. | |
| 9(Z),11(E),13(E)-Octadecatrienoic acid ethyl ester | 9(Z),11(E),13(E)-Octadecatrienoic acid ethyl ester (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. Synonyms: α-ESA ethyl ester; Ethyl α-eleostearate; 9Z,11E,13E-Octadecatrienoic acid ethyl ester. Grade: ≥98%. CAS No. 42021-86-3. Molecular formula: C20H34O2. Mole weight: 306.5. | |
| 9(Z),11(E),13(E)-Octadecatrienoic acid methyl ester | 9Z,11E,13E-Octadecatrienoic acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. Synonyms: α-ESA methyl ester; Methyl α-eleostearate. Grade: ≥98%. CAS No. 4175-47-7. Molecular formula: C19H32O2. Mole weight: 292.5. | |
| A01 | A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Study showed that it potentiated BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells. Synonyms: Smurf1-IN-A01; Smurf1INA01; Smurf1 IN A01; Smurf1 inhibitor A01; Smurf1-inhibitor-A01; A01; A 01; A-01; [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone; SMURF1 inhibitor A01. Grade: ≥98% by HPLC. CAS No. 1007647-73-5. Molecular formula: C22H20ClF3N4O3S. Mole weight: 512.93. | |
| A-1155463 | A-1155463, an effective and selective BCL-XL inhibitor, has been studied to have probable effect in restraining the growth of small cell lung cancer xenograft tumors. IC50: <0.01 nM (Ki). Uses: A-1155463 is an effective and selective bcl-xl inhibitor that has been studied to have probable effect in restraining the growth of small cell lung cancer xenograft tumors. Synonyms: CHEMBL3342332; A-1155463; A 1155463; A1155463; SCHEMBL2501550; BDBM50030754; CS-5398; HY-19725; CS 5398; HY 19725; CS5398; HY19725. Grade: 98%. CAS No. 1235034-55-5. Molecular formula: C35H32FN5O4S2. Mole weight: 669.79. | |
| A-1165442 | A-1165442 is a potent, competitive and orally available modality-differentiated second-generation TRPV1 antagonist with good analgesic efficacy and a temperature-neutral profile (IC50 = 9 nM for human TRPV1). Synonyms: A1165442; A 1165442; A-1165442; 1-[(4R)-7-chloro-2,2-bis(fluoromethyl)-3,4-dihydrochromen-4-yl]-3-(3-methylisoquinolin-5-yl)urea; 1-(7-chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea. CAS No. 1221443-94-2. Molecular formula: C22H20ClF2N3O2. Mole weight: 431.86. | |
| A-1210477 | A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over other Bcl-2 family members. Synonyms: A 1210477; A1210477; Abbvie Mcl-1 Inhibitor; 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid. Grade: 98%. CAS No. 1668553-26-1. Molecular formula: C46H55N7O7S. Mole weight: 850.04. | |
| A-1331852 | A-1331852, a substituted benzothiazole, is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL (Ki ≤ 10 pM). A-1331852 is an orally apoptosis-inducing agent that may have potential as improved cancer therapeutics. Synonyms: 3-(1-(((3r,5r,7r)-adamantan-1-yl)methyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)picolinic acid; A-1331852; A 1331852; A1331852; ABT-263; ABT-199; ABT 199; ABT199. CAS No. 1430844-80-6. Molecular formula: C38H38N6O3S. Mole weight: 658.81. | |
| A-192621 | A-192621 is a selective antagonist at endothelin ETB receptor with more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmented constrictor responses to ET-1. Synonyms: (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-(4-propoxyphenyl)pyrrolidine-3-carboxylic acid; (2R-(2alpha,3beta,4alpha)-4-(1,3-benzodioxol-5-yl)-1-(2-(2,6-diethylphenyl)amino)-2-oxoethyl)-2-(4-propoxyphenyl)-3-pyrrolidinecarboxylic acid; A 192621; A-192621; A192621. Grade: >98%. CAS No. 195529-54-5. Molecular formula: C33H38N2O6. Mole weight: 558.675. | |
| A-205804 | A-205804 is a potent, selective and orally bioavailable lead inhibitor of E-selectin and ICAM-1 expression, with IC50s of 20 and 25 nM for E-selectin and ICAM-1, respectively. It can be used in the study of chronic inflammatory diseases. Synonyms: 4-(p-Tolylthio)thieno[2,3-c]pyridine-2-carboxamide; 4-[(4-methylphenyl)thio]thieno[2,3-c]pyridine-2-carboxamide; 4-(p-Tolylsulfanyl)thieno[2,3-c]pyridine-2-carboxamide. Grade: >98%. CAS No. 251992-66-2. Molecular formula: C15H12N2OS2. Mole weight: 300.40. | |
| A-317491 | A-317491 is a potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors stimulate the pronociceptive effects of ATP upon activation. Uses: P2x3 and p2x2/3 receptor antagonist. Synonyms: ABT 202; A-317491 sodium; ABT202; A317491 sodium; ABT-202; A 317491 sodium; 5-[(3-phenoxyphenyl)methyl-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl]benzene-1,2,4-tricarboxylic acid. Grade: ≥95%. CAS No. 475205-49-3. Molecular formula: C33H27NO8. Mole weight: 565.57. | |
| A-317491 sodium salt hydrate | A-317491 sodium salt hydrate is a potent, selective antagonist of P2X3 and P2X2/3 receptors, with Kis of 22, 22, 9, and 92 nM for hP2X3, rP2X3, hP2X2/3, and rP2X2/3, respectively. It reduces inflammatory and neuropathic pain by blocking P2X3 and P2X2/3 receptor-mediated calcium flux. Grade: 99%. Molecular formula: C33H29NNaO9. Mole weight: 606.57. | |
| A-317567 | Acid Sensing Ion Channels (ASICs) are a group of sodium-selective ion channels that are activated by low extracellular pH. A-317567 is a novel non-amiloride blocker. Synonyms: A317567; 6-{2-[2-methyl-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]cyclopropyl}naphthalene-2-carboximidamide. CAS No. 371217-32-2. Molecular formula: C27H31N3. Mole weight: 397.56. | |
| A-366 | A-366 is a peptide-competitive inhibitor of the G9a/GLP histone lysine methyltransferase (IC50 = 3.3 nM) and is approximately 1000-fold selective over other methyltransferases. Synonyms: A 366; A366. CAS No. 1527503-11-2. Molecular formula: C19H27N3O2. Mole weight: 329.44. | |
| A-366833 | A-366833 is a an agonist at neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Uses: Neural nicotinic acetylcholine receptors selective for the α4β2 subtype. Synonyms: A-366833; A 366833; A366833; 5-[(1R,5S)-3,6-diazabicyclo[3.2.0]heptan-6-yl]pyridine-3-carbonitrile. Grade: ≥98%. CAS No. 370882-41-0. Molecular formula: C11H12N4. Mole weight: 200.24. | |
| A-381393 | A-381393 is a potent and selective dopamine D4 receptor agonist. Synonyms: A 381393; CHEMBL127257. Grade: 98%. CAS No. 726174-00-1. Molecular formula: 20H24N4. Mole weight: 320.4. | |
| A-395 | A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions, and can effectively inhibit the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM. Synonyms: 3-Pyrrolidinamine, 1-(7-fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-[4-[4-(methylsulfonyl)-1-piperazinyl]phenyl]-, (3R,4S)-; (3R,4S)-1-(7-Fluoro-2,3-dihydro-1H-inden-1-yl)-N,N-dimethyl-4-{4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}-3-pyrrolidinamine. Grade: ≥95%. CAS No. 2089148-72-9. Molecular formula: C26H35FN4O2S. Mole weight: 486.65. | |
| A-3 HYDROCHLORIDE | A-3 HYDROCHLORIDE. Synonyms: A-3 HYDROCHLORIDE; A-3; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HCL; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULFONAMIDE HYDROCHLORIDE; N-(2-AMINOETHYL)-5-CHLORONAPHTHALENE-1-SULPHONAMIDE HYDROCHLORIDE; N-(2-AMINOETHYL)-5-CHLORO-1-NAPHTHALENESULFONA. CAS No. 78957-85-4. Molecular formula: C12H14Cl2N2O2S. Mole weight: 321.22. | |
| A-438079 HCl | A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9. Synonyms: A-438079 HCl; A 438079 HCl; A438079 HCl. Grade: 98%. CAS No. 899431-18-6. Molecular formula: C13H10Cl3N5. Mole weight: 342.61. | |
| A-443654 | A-443654 is a potent small-molecule inhibitor of all three Akt serine/threonine kinases, induces Akt Ser-473 phosphorylation in all human cancer cell lines tested, including PTEN- and TSC2-deficient lines. It inhibits Akt-dependent signal transduction in cells and in vivo in a dose-responsive manner. Synonyms: A443564; A-443564; A 443564. Grade: >98%. CAS No. 552325-16-3. Molecular formula: C24H23N5O. Mole weight: 397.47. | |
| A-485 | A-485 is an inhibitor of the histone acetyltransferase p300/CBP (IC50 = 60 nM). Synonyms: (1R)-N-[(4-Fluorophenyl)methyl]-2,3-dihydro-5-[[(methylamino)carbonyl]amino]-2',4'-dioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]spiro[1H-indene-1,5'-oxazolidine]-3'-acetamide. Grade: ≥98%. CAS No. 1889279-16-6. Molecular formula: C25H24F4N4O5. Mole weight: 536.48. | |
| A[5']P5[5']A SODIUM SALT | A[5']P5[5']A SODIUM SALT is a paramount biomedical product, standing as a distinguished tool for selective autoimmune conditions and inflammatory dysfunctions. It exhibits its might as a formidable cGAS-STING pathway stimulator. Synonyms: Adenosine 5'-(hexahydrogen pentaphosphate), 5'.5'-ester with adenosine, pentasodium salt; P1,P5-Di(adenosine-5') pentaphosphate pentasodium salt; Diadenosine pentaphosphate pentasodium salt. Grade: ≥95%. CAS No. 4097-4-5. Molecular formula: C20H24N10Na5O22P5. Mole weight: 1026.28. | |
| A-674563 | A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC. Synonyms: A674563; A 674563; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine. Grade: >98%. CAS No. 552325-73-2. Molecular formula: C22H22N4O. Mole weight: 358.44. | |
| A-674563 dihydrochloride | A-674563, an Akt1 inhibitor with a Ki of 11 nM, is moderately potent against PKA and >30-fold selective for Akt1 over PKC. Synonyms: A-674563 2HCl; Benzeneethanamine, α-[[[5-(3-methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]-, hydrochloride (1:2), (αS)-; (αS)-α-[[[5-(3-Methyl-1H-indazol-5-yl)-3-pyridinyl]oxy]methyl]benzeneethanamine dihydrochloride; (S)-1-((5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl)oxy)-3-phenylpropan-2-amine hydrochloride; A 674563 dihydrochloride; A674563 dihydrochloride. Grade: ≥95%. CAS No. 2759293-92-8. Molecular formula: C22H22N4O.2HCl. Mole weight: 431.36. | |
| A-674563 hydrochloride | A-674563 hydrochloride is a potent, orally available Akt1 inhibitor with Ki of 11 nM. Synonyms: (S)-1-(5-(3-methyl-1H-indazol-5-yl)pyridin-3-yloxy)-3-phenylpropan-2-amine hydrochloride. Grade: 98%. CAS No. 2070009-66-2. Molecular formula: C22H23ClN4O. Mole weight: 394.90. | |
| A-71623 | A-71623 is a tetrapeptide and acts as a potent CCK1 agonist (IC50 = 3.7 nM) displaying 1200-fold selectivity over the CCK2 receptor. A-71623 is used to suppress appetite and reduce food intake following central or peripheral administration. Synonyms: A 71623; A-71623; A71623; N-[(1,1-Dimethylethoxy)carbonyl]-L-tryptophyl-N6-[[(2-methylphenyl)amino]carbonyl]-L-lysyl-L-α-aspartyl-Nα-methyl-L-phenylalaninamide. CAS No. 130408-77-4. Molecular formula: C44H56N8O9. Mole weight: 840.97. | |
| A-740003 | A-740003 is potent, selective and competitive P2X7 receptor antagonist. Its IC50 values are 18 and 40 nM for rat and human receptors respectively measured by agonist-stimulated changes in intracellular calcium concentrations. It displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. It reduces nociception in animal models of persistent neuropathic and inflammatory pain. It showed weak or no activity (IC(50) > 10 muM) at other P2 receptors and an array of other neurotransmitter and peptide receptors, ion channels, reuptake sites, and enzymes. It potently blocked agonist-evoked IL-1beta release (IC(50) = 156 nM) and pore formation (IC(50) = 92 nM) in differentiated human THP-1 cells. It produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Uses: A-740003 produces significant antinociception in animal models of neuropathic and inflammatory pain in vivo. Synonyms: A-740003; A 740003; A740003; N-[1-[[(Cyanoamino)(5-quinolinylimino)methyl]amino]-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide; N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide. Grade: >98 %. CAS No. 861393-28-4. Molecular formula: C26H30N6O3. Mole weight: 474.55. | |
| A-769662 | A-769662 is a potent, reversible AMPK activator with EC50 of 0.8 μM in cell-free assays, little effect on GPPase/FBPase activity. Synonyms: 4-Hydroxy-3-(2'-hydroxy-[1,1'-biphenyl]-4-yl)-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile. Grade: ≥95%. CAS No. 844499-71-4. Molecular formula: C20H12N2O3S. Mole weight: 360.4. | |
| A-770041 | A-770041 is an selective and orally bioavailable pyrazolo[3,4-d]pyrimidine exhibiting selectivity for Lck compared with previously reported compounds. It is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling. It is currently in the preclinical developlent stage and no clinical data are available. Synonyms: A-770041; A 770041; A770041. Grade: >98%. CAS No. 869748-10-7. Molecular formula: C34H39N9O3. Mole weight: 621.73. | |
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