BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Phleomycin | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. The therapeutic index of the complex for Solid Adenocarcinoma and Sarcoma-180 are 16. The therapeutic index of Ehrlician ascites cancer is 4-8. It acts an antibiotic originally, an anticancer agent and a selection agent for transformed algae, protista, animal and fungal cells. Synonyms: Bleomycin; phleomycin complex; Phleomycins. CAS No. 11006-33-0. Molecular formula: C51H75N17O21S2. Mole weight: 1326.37. |  |
| Phleomycin E | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 12.5-25 μg/mL. It inhibits airy entity carcinoma in mice with IC50 of 0.31 μg/mL. Synonyms: N1- [4- [ [ [ [4- [ [Aminoiminomethyl]amino]butyl]amino] (imino) methyl]amino]butyl]-7, 8-dihydrobleomycinamide; Bleomycinamide, N1- [4- [ [ [ [4- [ (aminoiminomethyl) amino] butyl] amino] iminomethyl] amino] butyl] -7, 8-dihydro-. CAS No. 11031-13-3. Molecular formula: C60H97N23O21S2. Mole weight: 1540.68. | |
| Phleomycin F | It is produced by the strain of Streptoverticillium verticillum 843-1. It's a heteropeptide antibiotic. It has anti-gram-positive bacteria, negative bacteria and mycobacterium effects. It extends the survival time of mice transplanted with Ehrman's ascites cancer by 300 percent with MED of 25-50 μg/mL. Synonyms: Bleomycin B4; Dehydrophleomycin E; N1- [4- [ (Aminoiminomethyl) [4- [ (aminoiminomethyl) amino] butyl] amino] butyl] bleomycinamide; Bleomycinamide, N1-[4-[ (aminoiminomethyl) [4-[ (aminoiminomethyl) amino]butyl]amino]butyl]-. CAS No. 9060-11-1. Molecular formula: C60H95N23O21S2. Mole weight: 1538.67. | |
| Phomaligol A | Phomaligol A is an antibacterial metabolite produced from marine-derived fungus Aspergillus flavus. Synonyms: Butanoic acid, 2-methyl-, (1R,5R)-5-hydroxy-4-methoxy-1,5-dimethyl-2,6-dioxo-3-cyclohexen-1-yl ester, (2S)-. Grades: ≥98%. CAS No. 152204-32-5. Molecular formula: C14H20O6. Mole weight: 284.31. | |
| Phomopsin A | It is an acidic 13-membered cyclic hexapeptide-like metabolite with three unusual amino acids. It is a potent mycotoxin produced by the fungus, phomopsis leptostromiformis. It is an important bioprobe for understanding cellular structural proteins. It selectively binds to the dimeric tubulin at the overlap of vinblastine and maytansine, inhibits the formation of the microtubule spindle to block cell division. Synonyms: 2-Oxa-5,8-diazabicyclo[10.3.1]hexadecane, cyclic peptide deriv.; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-(2E)-2,3-didehydroisoleucyl-2,3-didehydro-aspartic acid, cyclic (15?3)-ether; NSC 381839; PMSA; Phomopsin. Grades: >98% by HPLC. CAS No. 64925-80-0. Molecular formula: C36H45ClN6O12. Mole weight: 789.23. | |
| Phomopsinamine | Phomopsinamine is a potent mycotoxin and an effective microtubule inhibitor produced by the fungus, Phomopsis leptostromiformis. Phomopsinamine is formed by hydrolysis of the dicarboxylic acid of phomopsin A. Synonyms: Isoleucinamide, (βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-, cyclic (15?3)-ether, (2E)-; Phomopsinamine A; (2E)-(βS)-3-chloro-β,5-dihydroxy-N-methyl-L-tyrosyl-3,4-didehydro-L-valyl-3-hydroxy-L-isoleucyl-3,4-didehydro-L-prolyl-2,3-didehydro-isoleucinamide, cyclic (15?3)-ether; (S)-N-((E)-1-amino-3-methyl-1-oxopent-2-en-2-yl)-1-((3R,4S,7S,10S,11S)-15-chloro-3-ethyl-16,11-dihydroxy-3-methyl-10-(methylamino)-6,9-dioxo-7-(prop-1-en-2-yl)-2-oxa-5,8-diaza-1(1,3)-benzenacycloundecaphane-4-carbonyl)-2,5-dihydro-1H-pyrrole-2-carboxamide. Grades: >95% by HPLC. CAS No. 89085-54-1. Molecular formula: C32H43ClN6O8. Mole weight: 675.17. | |
| Phoslactomycin A | It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Propanoic acid, 2-methyl-, (1S,3R)-3-[(1Z,3Z,5R,7R,8R,9E)-8-(2-aminoethyl)-10-[(2S,3S)-3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl]-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrien-1-yl]cyclohexyl ester; Propanoic acid, 2-methyl-, 3-[8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl]cyclohexyl ester, [2S-[2a[1Z(1R*, 3S*), 3Z, 5S*, 7S*, 8S*, 9E], 3a]]-; (+)-Phoslactomycin A. CAS No. 122856-25-1. Molecular formula: C29H46NO10P. Mole weight: 599.65. | |
| Phoslactomycin B | It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: (+)-Phoslactomycin B; 2H-Pyran-2-one, 6-[(1E,3R,4R,6R,7Z,9Z)-3-(2-aminoethyl)-10-cyclohexyl-3,6-dihydroxy-4-(phosphonooxy)-1,7,9-decatrien-1-yl]-5-ethyl-5,6-dihydro-, (5S,6S)-. CAS No. 122856-26-2. Molecular formula: C25H40NO8P. Mole weight: 513.56. | |
| Phoslactomycin C | It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Phosphazomycin C1; Butanoic acid, 3-methyl-, 3-[8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl]cyclohexyl ester. CAS No. 122856-27-3. Molecular formula: C30H48NO10P. Mole weight: 613.67. | |
| Phoslactomycin D | It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Pentanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-28-4. Molecular formula: C31H50NO10P. Mole weight: 627.70. | |
| Phoslactomycin E | It is produced by the strain of Str. nigrescens. It is the main component, which has weak effect against gram-positive bacteria, but has strong effect against fungi. Synonyms: Cyclohexanecarboxylic Acid, 3-(8-(2-Aminoethyl)-10-(3-Ethyl-3,6-Dihydro-6-Oxo-2H-Pyran-2-Yl)-5,8-Dihydroxy-7-(Phophonooxy)-1,3,9-Decatrienyl)Cyclohexyl Ester. CAS No. 122856-29-5. Molecular formula: C32H50NO10P. Mole weight: 639.71. | |
| Phoslactomycin F | It is produced by the strain of Str. nigrescens. The main component E has weak effect against gram-positive bacteria, but has strong effect against fungi. Its antimicrobial activity is similar to Phoslactomycin E. Synonyms: Hexanoic acid, 4-methyl-, 3-(8-(2-aminoethyl)-10-(3-ethyl-3,6-dihydro-6-oxo-2H-pyran-2-yl)-5,8-dihydroxy-7-(phosphonooxy)-1,3,9-decatrienyl)cyclohexyl ester. CAS No. 122856-30-8. Molecular formula: C32H52NO10P. Mole weight: 641.73. | |
| Phosmidosine | It is produced by the strain of Str. sp. RK-16. It can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. It has antifungal effect. Synonyms: Phosmidosine A; Adenosine, 7,8-dihydro-8-oxo-, 5'- (methyl (2-pyrrolidinylcarbonyl) phosphoramidate) , (S)-; 5'-O-[Methoxy[[[(2S)-pyrrolidin-2α-yl]carbonyl]amino]phosphinyl]-7,8-dihydro-8-oxoadenosine; Adenosine, 7,8-dihydro-8-oxo-, 5'-[methyl N- [ (2S) -2-pyrrolidinylcarbonyl] phosphoramidate]. CAS No. 134966-01-1. Molecular formula: C16H24N7O8P. Mole weight: 473.38. | |
| Phosmidosine B | It is produced by the strain of Str. sp. RK-16. It can inhibit the cell cycle progression and cell morphology recovery of srcts-NRK cells. Synonyms: Adenosine, 7,8-dihydro-8-oxo-, 5'- [hydrogen [ (2S) -2-pyrrolidinylcarbonyl] phosphoramidate] ; Adenosine, 7,8-dihydro-8-oxo-, 5'-[hydrogen (2-pyrrolidinylcarbonyl) phosphoramidate], (S)-. CAS No. 146425-23-2. Molecular formula: C15H22N7O8P. Mole weight: 459.35. | |
| Phosphonomycin Calcium salt | It is produced by the strain of Str. fradiae NRRL-3417, Str. viridchromogenes NRRL-3413. It's an antibiotic that contains phosphorus. It has anti-gram positive bacterial and negative bacterial activity, inorganic phosphorus and sodium chloride can reduce its activity. It has protective effect on mice infected with Staphylococcus aureus, Salmonella typhi and Salmonella paratyphi B by oral administration. Synonyms: (-)-Phosphonomycin Calcium salt; Calcium fosfomycin; fosfomycin calcium; Fosmicin; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1); Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-; Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1); Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-. Grades: 98%. CAS No. 26016-98-8. Molecular formula: C3H5O4P.Ca. Mole weight: 176.12. | |
| Phosphoramidon | Phosphoramide is an inhibitor of pyrolytic enzyme derived from the culture of Streptomyces tanashiensis. Synonyms: N-(alpha-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan. Grades: >98%. CAS No. 119942-99-3. Molecular formula: C23H34N3O10P.xNa. Mole weight: 543.50 (free acid). | |
| Pht-Gly-β-Ala-OH | Synonyms: Phthaloyl-glycyl-β-alanine; 3-(2-(1,3-Dioxoisoindolin-2-yl)acetamido)propanoic acid; Pht Gly β Ala OH. Grades: ≥ 99%. CAS No. 17896-84-3. Molecular formula: C13H12N2O5. Mole weight: 276.25. | |
| Phthaloyl-β-alanine | Synonyms: Pht-β-Ala-OH; 3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)propionic acid; 3-(1,3-Dioxoisoindolin-2-yl)propanoic acid; 3-Phthalimidopropionic acid; 2H-Isoindole-2-propanoic acid, 1,3-dihydro-1,3-dioxo-; 3-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid; 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid; N-PHTHALOYL-BETA-ALANINE; PHT-BETA-ALA-OH; PHT BETA ALA OH. Grades: ≥ 98% (HPLC). CAS No. 3339-73-9. Molecular formula: C11H9NO4. Mole weight: 219.19. | |
| Phyllosinol | It is produced by the strain of Phyllosticta sp. pH-A. It's an antifungal antibiotic. It has the same effect as Sphaeropsidin and Epoxydon. Synonyms: Epoxydon; Epoxydone; (+)-Parasitenone; (+)-Epoxydon; NSC 93049; Antibiotic 212T2; 7-Oxabicyclo[4.1.0]hept-3-en-2-one, (1R,5R,6R)-; 7-Oxabicyclo[4.1.0]hept-3-en-2-one, [1R-(1alpha,5beta,6alpha)]-. Grades: 95%. CAS No. 24292-29-3. Molecular formula: C7H8O4. Mole weight: 156.14. | |
| Physciosporin | Physciosporin (PHY) is an effective secondary metabolite found in lichens and isolated from Pseudocyphellaria coriacea. It inhibits the motility of lung cancer cells. Synonyms: 2-Chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-11H-dibenzo[b,e][1,4]dioxepin-7-carboxylic acid methyl ester; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 2-chloro-4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-, methyl ester; methyl 8-chloro-10-formyl-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylate; Chlorgranulatin; Methyl 5-chlorovirensate. CAS No. 64662-25-5. Molecular formula: C19H15ClO8. Mole weight: 406.77. | |
| PI-083 | PI-083 is a platelet aggregation inhibitor produced by Streptomyces matensis A-6621. It is active against gram-positive bacteria with MIC of 0.39-3.13 μg/mL. It inhibits platelet aggregation induced by ADP, Arachidonic Acid and collagen with MIC of 30.4, 1.9 and 3.8 μmol/L. It also inhibits KB cell growth with IC50 of 0.026 μmol/L. Synonyms: PI 083; PI083. CAS No. 119341-57-0. Molecular formula: C43H50O16. Mole weight: 822.8. | |
| PI-200 | PI-200 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 3.8 x 10(-4) M. Synonyms: PI 200; PI200. CAS No. 143605-57-6. Molecular formula: C17H26O2. Mole weight: 262.4. | |
| PI-201 | PI-201 is a platelet aggregation inhibitor produced by Streptomyces sp. A7498. It inhibited ADP-induced aggregation of rabbit platelets with IC50 of 7.1 x 10(-4) M. Synonyms: PI 201; PI201. CAS No. 143605-56-5. Molecular formula: C17H28O3. Mole weight: 280.4. | |
| Piericidin A | Piericidin A (AR-054) is a natural mitochondrial NADH-ubiquinone oxidoreductase (complex I) inhibitor. Piericidin A is a potent neurotoxin and inhibits mitochondrial respiration by disrupting the electron transport system through its action on NADH-ubiquinone reductase. Piericidin A is also a potential quorum-sensing inhibitor that suppresses the expression of the virulence genes of Erwinia carotovora subsp. atroseptica (Eca). Piericidin A is an ADC cytotoxin and has anti-bacterial, anticancer, insecticidal activity. Synonyms: Shaoguanmycin B. Grades: >95.0%. CAS No. 2738-64-9. Molecular formula: C25H37NO4. Mole weight: 415.57. | |
| Piericidin B | It is produced by the strain of Str. mobaraensis 16-24. It has anti-fungal, gram-positive bacteria and insect effects, but also has weak anti-gram-negative bacteria effect. Synonyms: Piericidin B1; (-)-Piericidin B1; 4-Pyridinol, 2,3-dimethoxy-6-(10-methoxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-5-methyl-, (S-(R*,R*-(all-E)))-; 4-Pyridinol, 2,3-dimethoxy-6-[(2E,5E,7E,9R,10R,11E)-10-methoxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5-methyl-. CAS No. 16891-54-6. Molecular formula: C26H39NO4. Mole weight: 429.59. | |
| Pikromycin | Pikromycin is a macrolide antibiotic that is biosynthesised by Streptomyces venezuelae. It is an inhibitor of Prolyl endopeptidase (PREP) and has an inhibitory effect on E. coli, S. aureus, B. subtilis and mycobacteria. Synonyms: (3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradec-11-ene-2,4,10-trione; Albomycetin; Amaromycin; Antibiotic B 62169A; [3R-(3R*,5R*,6S*,7S*,9R*,11E,13S*,14R*)]-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradec-11-ene-2,4,10-trione; Picromycin. Grades: ≥95% by HPLC. CAS No. 19721-56-3. Molecular formula: C28H47NO8. Mole weight: 525.67. | |
| Pilatin | It is produced by the strain of Flagelloscypha pilatii JK 322. Like Marasmic acid, it has inhibitory effects on bacteria and fungi, and has strong inhibitory effects on the incorporation of thymidin and ureidin into DNA and RNA in Ehrlich carcinoma ascites cells. It can cause frameshift mutations in Salmonella typhimuium TA98. Synonyms: 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-3,5a-dihydroxy-7,7-dimethyl-4-formyl-1-oxo-3H,6H,3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3-alpha,3a-beta,5a-beta,6-alpha(E),8a-beta,9b-beta))-; 2-Hexenoic acid, 5a,7,8,8a-tetrahydro-4-formyl-3,5a-dihydroxy-7,7-dimethyl-1-oxo-3H,6H-3a,8b-methano-1H-indeno(4,5-c)furan-6-yl ester, (3S-(3alpha, 3abeta, 5abeta, 6alpha(E), 8abeta, 9bbeta))-. CAS No. 119525-97-2. Molecular formula: C21H26O7. Mole weight: 390.43. | |
| Piloquinone | It is produced by the strain of Str. pilosus. It's a phenanthrene compound. It has inhibitory effect on mycobacterium and protozoa, but the effect is not strong. Synonyms: 9,10-Phenanthrenedione, 1,8-dihydroxy-2-methyl-3-(4-methyl-1-oxopentyl)-; 1,8-Dihydroxy-2-methyl-3-(4-methylpentanoyl)-9,10-phenanthrenedione. CAS No. 25414-26-0. Molecular formula: C21H20O5. Mole weight: 352.38. | |
| Pimprinethine | Pimprinethine is a pyrazoloisoquinolinone antibiotic produced by Streptoverticillium griseocarneum. It has weak anti-Gram-positive bacteria activity. Synonyms: APHE-1. CAS No. 146426-35-9. Molecular formula: C13H12N2O. Mole weight: 212.25. | |
| Pinselin | It is produced by the strain of Penicillium sp., Pen. amarum. It is a nitrogen-containing heterocyclic antibiotic. It has anti-yeast activity. Synonyms: Pincelin; 9H-Xanthene-1-carboxylic acid, 2,8-dihydroxy-6-methyl-9-oxo-, methyl ester; Cassiollin; 1,7-Dihydroxy-8-methoxycarbonyl-3-methylxanthon. CAS No. 476-53-9. Molecular formula: C16H12O6. Mole weight: 300.26. | |
| Pintulin | It is produced by the strain of Penicillium vulpinum F-4148. In in vitro test, it can inhibit P388, L 1210, HL-60, KB and other tumor cell lines with IC50 (μg/mL) of 0.8, 0.8, 0.8, 0.25, respectively. It has only very weak antibacterial activity against the microorganisms tested. Molecular formula: C14H12O5. Mole weight: 260.24. | |
| Pipacycline | A semi-synthetic tetracycline formed by a mannich condensation of formaldehyde and 4-hydroxyethylpiperazine with tetracyclin. It inhibits the formation of penicillinase, the enzyme that inactivates penicillin in bacteria. It is used in salt form with penicillin V for parenteral use. Synonyms: Mepicycline; Pipacyclinum. Grades: >98% by HPLC. CAS No. 1110-80-1. Molecular formula: C29H38N4O9. Mole weight: 586.63. | |
| Pipemidic acid | Pipemidic acid is a synthetic quinolone antibiotic agent as an ATP-sensitive K+ channel blocker. Uses: Atp-sensitive k+ channel blocker. Synonyms: Deblaston; Pipram; Uromidin; RB 1489; RB-1489; RB1489. Grades: ≥95%. CAS No. 51940-44-4. Molecular formula: C14H17N5O3. Mole weight: 303.32. | |
| Piperafizine A | It is a methylated diketopiperazine formed by the condensation of phenylalanine and is produced by many species in the genus Streptomyces. It exhibits little activity in vitro but potentiates vincristine antitumour potency. Synonyms: 3,6-Dibenzylidene-1-methyl-2,5-dioxopiperazine. Grades: >99% by HPLC. CAS No. 130603-59-7. Molecular formula: C19H16N2O2. Mole weight: 304.34. | |
| Piperazinomycin | It is produced by the strain of Streptoverticillium olivoreticuli subsp. neoenacticus. It has anti-fungal, yeast, some mycobacterium effects, but no anti-bacterial effect. Synonyms: (+)-piperazinomycin; 13-Oxa-4, 20-diazatetracyclo[12.2.2.23, 6.18, 12]heneicosa-8, 10, 12(19), 14, 16, 17-hexaen-11-ol, (3S,6S)-. CAS No. 83858-82-6. Molecular formula: C18H20N2O2. Mole weight: 296.36. | |
| Piptamine | It is produced by the strain of Piptoporus sp. Lu 9-1. It has broad antibacterial spectrum, it inhibits Staphylococcus aureus, enterococcus faecalis, Bacillus subtilis, Escherichia coli, Candida albicans with MIC (μg/mL) of 0.78-6.25, 1.56, 1.00, 12.5, 6.25, respectively. Molecular formula: C23H41N. Mole weight: 331.58. | |
| Pirarubicin hydrochloride | Pirarubicin Hydrochloride is an analogue of the anthracycline anti-neoplastic doxorubicin, which is an inhibitor of Topo II. It intercalates into DNA and interacts with topoisomerase II, thereby inhibiting replication and repair of DNA and RNA, and protein synthesis. It is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines. Uses: Antineoplastic agents. Synonyms: THP Hydrochloride. Grades: >98%. CAS No. 95343-20-7. Molecular formula: C32H38ClNO12. Mole weight: 664.10. | |
| Pirlimycin | A semi-synthetic lincosamide prepared from clindamycin by hydrolysing the propyl N-methylproline and re-annealing a 4-ethylpipecolic acid. It is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans by binding to the 23S ribosomal subunit, blocking protein synthesis. Synonyms: U-57930E; methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside. Grades: >99% by HPLC. CAS No. 79548-73-5. Molecular formula: C17H31ClN2O5S. Mole weight: 410.96. | |
| Pirlimycin Hydrochloride | A salt of the semi-synthetic tetracycline analogue, pirlimycin. It is a broad spectrum lincosaminide antibiotic with activity against anaerobic bacteria and protozoans by binding to the 23S ribosomal subunit, blocking protein synthesis. It is also an impurity of Clindamycin. Synonyms: Pirsue; U 57930E; (2S-cis)-methyl 7-Chloro-6,7,8-trideoxy-6-[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside Monohydrochloride. Grades: >99% by HPLC. CAS No. 78822-40-9. Molecular formula: C17H31ClN2O5S.HCl. Mole weight: 447.42. | |
| Platelet Factor 4 (58-70), human | It is the 58-70 amino acid fragment of Platelet Factor 4 (PF-4) that contains the major heparin-binding domain and is insufficient to fully exert its antiangiogenic activity. Synonyms: PF4 (58-70) (human); Pro-Leu-Tyr-Lys-Lys-Ile-Ile-Lys-Lys-Leu-Leu-Glu-Ser; L-prolyl-L-leucyl-L-tyrosyl-L-lysyl-L-lysyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-lysyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-serine; platelet factor 4 fragment 58-70 human. Grades: 95%. CAS No. 82989-21-7. Molecular formula: C76H133N17O18. Mole weight: 1572.97. | |
| Platencin | Platencin is a broad-spectrum Gram-positive antibiotic produced by Streptomyces. Platencin is an effective antibiotic against FabF and FabH proteins. No toxicity was observed. Grades: >99% by HPLC. CAS No. 869898-86-2. Molecular formula: C24H27NO6. Mole weight: 425.47. | |
| Platenomycin C3 | Platenomycin C3 is a macrolide antibiotic produced by Str. platensis subsp. malvinus MCRL-0388 (FERM-P289). Activity against gram-positive bacteria. Synonyms: Maridomycin I; Turimycin EP5; Antibiotic B 5050A; Antibiotic yl-704C3. Grades: >98%. CAS No. 35908-44-2. Molecular formula: C43H71NO16. Mole weight: 858.02. | |
| Platensimycin | Platensimycin is a broad spectrum, gram-positive antibiotic produced by strains of streptomyces platensis. It inhibits bacterial growth by selectively inhibiting the elongation enzyme, b-ketoacyl acyl carrier protein synthase (fabf) of the fatty acid synthesis pathway. Synonyms: (-)-Platensimycin. Grades: >95% by HPLC. CAS No. 835876-32-9. Molecular formula: C24H27NO7. Mole weight: 441.47. | |
| Pluracidomycin A1 | Pluracidomycin A1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 7-oxo-3-sulfo-6-(1-(sulfooxy)ethyl)-, (5R-(5alpha,6beta(S*)))-; Pluracidomycin; Pluracidomycin A; SF 2103 A. Grades: >98%. CAS No. 82138-64-5. Molecular formula: 9H11NO10S2. Mole weight: 357.31. | |
| Pluracidomycin B | Pluracidomycin B is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. CAS No. 82138-65-6. Molecular formula: C11H13NO10S2. Mole weight: 383.35. | |
| Pluracidomycin C1 | Pluracidomycin C1 is a carbapenem antibiotic produced by Str. pluracidomyceticus nov. sp. It has anti-gram-positive bacteria and gram-negative bacteria activity, and has the effect of inhibiting β-lactamase. Synonyms: Pluracidomycin C. CAS No. 82138-66-7. Molecular formula: C10H13NO10S2. Mole weight: 371.34. | |
| Pluraflavin A | Pluraflavin A is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. Pluraflavin A has the effect of inhibiting the transcription of glucose-6-phosphatase gene and has good anti-proliferation activity on tumor cells. Molecular formula: C43H54N2O14. Mole weight: 822.89. | |
| Pluraflavin C | Pluraflavin C is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C43H56N2O15. Mole weight: 840.91. | |
| Pluraflavin E | Pluraflavin E is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells. Molecular formula: C36H41NO14. Mole weight: 711.71. | |
| Pluviatolide | Pluviatolide is a butyrolactone lignan first isolated from the Australian native plant, Zanthoxylum pluviatile. It has a variety of biological activities, including antioxidant, enzyme inhibitory effect and antispasmodic properties. Synonyms: (-)-Pluviatolide; 2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-; 3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one; 4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one; trans-Pluviatolide; (3R,4R)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one. Grades: ≥95% by HPLC. CAS No. 28115-68-6. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| PM-94128 | PM-94128. Synonyms: PM 94128; PM94128. CAS No. 182292-49-5. Molecular formula: C22H34N2O6. Mole weight: 422.5. | |
| PM-Toxin A | PM-Toxin A is a toxin produced by Phyllosticta maydis. Synonyms: PM Toxin A. CAS No. 88212-12-8. Molecular formula: C33H60O8. Mole weight: 584.8. | |
| PM-Toxin B | PM-Toxin B is a toxin produced by Phyllosticta maydis. Synonyms: PM Toxin B. CAS No. 87879-56-9. Molecular formula: C33H62O8. Mole weight: 586.8. | |
| PM-Toxin C | PM-Toxin C is a toxin produced by Phyllosticta maydis. Synonyms: PM Toxin C. CAS No. 87879-55-8. Molecular formula: C35H66O9. Mole weight: 630.9. | |
| PM-Toxin D | PM-Toxin D is a toxin produced by Phyllosticta maydis. Synonyms: PM Toxin D. CAS No. 88212-13-9. Molecular formula: C33H62O9. Mole weight: 602.8. | |
| Pneumocandin A4 | Pneumocandin A4 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Synonyms: 10,12-Dimethyl-tetradecanoic acid {3-(2-carbamoyl-1-hydroxy-ethyl)-11,25-dihydroxy-15-(1-hydroxy-ethyl)-6-[2-(4-hydroxy-phenyl)-ethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaaza-tricyclo[22.3.0.0~9,13~]heptacos-18-yl}-amide. Molecular formula: C51H82N8O13. Mole weight: 1015.24. | |
| Pneumocandin B2 | Pneumocandin B2 is a lipopeptide antibiotic produced by Zalerion arboricola. It has a strong anti-Candida effect. It has the effect of inhibiting the synthesis of 1,3 early-glucan in vitro, with an IC50 of 0.07-0.5 μg/mL. Synonyms: 10,12-Dimethyl-tetradecanoic acid [3-(2-carbamoyl-1-hydroxy-ethyl)-6-[1,2-dihydroxy-2-(4-hydroxy-phenyl)-ethyl]-11,25-dihydroxy-15-(1-hydroxy-ethyl)-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaaza-tricyclo[22.3.0.0~9,13~]heptacos-18-yl]-amide. Molecular formula: C50H80N8O15. Mole weight: 1033.21. | |
| p-Nitrophenylacetic acid N-hydroxysuccinimide ester | Synonyms: Succinimidyl-p-nitrophenylacetate. Grades: ≥ 98% (HPLC). CAS No. 68123-33-1. Molecular formula: C12H10N2O6. Mole weight: 278.22. | |
| Polyhydroxybutyrate | Polyhydroxybutyrate is a polyester that is produced by microorganisms. Synonyms: PHB; Poly[oxy(1-methyl-3-oxo-1,3-propanediyl)]; Poly(oxycarbonylpropylene); (R,S)-β-butyrolactone homopolymer. CAS No. 26744-04-7. Molecular formula: (C4H6O2)n. | |
| Polymyxin B1 | Polymyxin B1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Synonyms: 4,10-anhydro{N-[(6R)-6-methyloctanoyl]-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine}; polymycin B. Grades: ≥95%. CAS No. 4135-11-9. Molecular formula: C56H98N16O13. Mole weight: 1203.47. | |
| Polymyxin B1 Sulfate | It is produced by the strain of Pseudomonas sp. It is one of the polypeptide fractions in polymyxin B sulfate. Polymyxin B1 is an antibacterial compound. It has a high volume of distribution and longer elimination half-life in patients with multidrug-resistant gram-negative bacterial infection. Synonyms: Polymyxin B1 sulfate salt (1:1); N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide sulfate (1:1). Grades: >90.0%. CAS No. 108965-61-3. Molecular formula: C56H98N16O13.H2SO4. Mole weight: 1301.55. | |
| Polymyxin B2 | Polymyxin B2 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Grades: >98%. CAS No. 34503-87-2. Molecular formula: C55H96N16O13. Mole weight: 1189.45. | |
| Polymyxin B3 sulfate | It is produced by the strain of Pseudomonas sp. Polymyxin B3 sulfate is an individual fraction found in the antibiotic mixture polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grades: ≥90.0% by HPLC. Molecular formula: C55H96N16O13.xH2O4S. Mole weight: 1189.45 (free base). | |
| Polymyxin B6 sulfate | It is produced by the strain of Bacillus Polymyxa. Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Grades: >90.0%. Molecular formula: C56H98N16O14.xH2SO4. Mole weight: 1219.47 (free base). | |
| Polymyxin D1 | Polymyxin D1 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. CAS No. 10072-50-1. Molecular formula: C50H93N15O15. Mole weight: 1144.36. | |
| Polymyxin D2 | Polymyxin D2 is a cyclic peptide antibiotic of Bacillus polymyxa. The effect of anti-gram-negative bacteria is greater than that of anti-gram-positive bacteria. Grades: >98%. CAS No. 34167-45-8. Molecular formula: C49H91N15O15. Mole weight: 1130.33. | |
| Polymyxin E1 Sulfate | It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E1 Sulfate is sulfate salt form of Polymyxin E1, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin A Sulfate; Polymixin E1 Sulfate salt; Colistin IV Sulfate; N2-(6-Methyl-1-oxooctyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine Cyclic (10?4)-Peptide Sulfate. Grades: ≥90.0% by HPLC. Molecular formula: C53H100N16O13.xH2SO4. Mole weight: 1169.46 (free base). | |
| Polymyxin E2 Sulfate | It is produced by the strain of Bacillus polymyxa var. colistinus. Polymyxin E2 Sulfate is sulfate salt form of Polymyxin E2, which is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria. Synonyms: Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10?4)-Lactam Sulfate Salt. Grades: ≥90.0% by HPLC. CAS No. 1338055-88-1. Molecular formula: C52H98N16O13.xH2SO4. Mole weight: 1155.43 (free base). | |
| Polymyxin Ile-B1 Sulfate | It is produced by the strain of Pseudomonas Sp. It is one of the individual polypeptide components in polymyxin B sulfate. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram-negative bacteria leading to lysing of the cell. Synonyms: Polymyxin B1-I sulfate; Polymyxin II Sulfate; Polymyxin B1 Isoleucine sulfate. Grades: ≥90.0%. Molecular formula: C56H98N16O13.xH2O4S. Mole weight: 1203.47 (free base). | |
| Polymyxin S1 | Polymyxin S1 is a cyclic peptide antibiotic of Bacillus polymyxa RS-6. Activity against gram-positive bacteria. Synonyms: Polymyxin D1, 6-D-phenylalanine. CAS No. 63700-38-9. Molecular formula: C53H91N15O15. Mole weight: 1178.38. | |
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