BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Acetyl Vardenafil | Acetyl Vardenafil is an analogue of Vardenafil. Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction. Synonyms: 2-[2-Ethoxy-5-[2-(4-ethyl-1-piperazinyl)acetyl]phenyl]-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one. CAS No. 1261351-28-3. Molecular formula: C25H34N6O3. Mole weight: 466.59. |  |
| Acetyl Vitamin B12 | Acetyl Vitamin B12 is a derivative of Vitamin B12. Vitamin B12 gets converted by the body into its bioactive forms, methylcobalamin and cobamamide, which serve as enzyme cofactors. Severe deficiency may result in megaloblastic anemia and/or neurological impairment. Synonyms: Coβ-cyano-O5R-acetylcobalamin. Grade: 80%. CAS No. 855207-36-2. Molecular formula: C65H90CoN14O15P. Mole weight: 1397.4. | |
| ACG548B | ACG548B is a potent inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50s of 1.78 and 0.496 μM, respectively. It has higher AChE affinity and selectivity over BChE and ChoK (choline kinase). Synonyms: ACG-548B; 1,1'-([1,1'-biphenyl]-3,3'-diylbis(methylene))bis(4-((4-chlorophenyl)(methyl)amino)pyridin-1-ium) bromide. CAS No. 795316-16-4. Molecular formula: C38H34Br2Cl2N4. Mole weight: 777.42. | |
| Ac-Gly1-Terlipressin | An impurity of Terlipressin. Terlipressin is a synthetic vasopressin analogue primarily used to improve kidney function in adults with hepatorenal syndrome (HRS), a condition that causes kidney problems in individuals with severe liver disease. It acts as a vasoconstrictor, predominantly in the splanchnic circulation, which helps increase arterial pressure and reduce portal venous pressure. Synonyms: Ac-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2(Cys4&Cys9 bridge); N1-Acetylterlipressin; Ac-GGGCYFQNCPKG-NH2(Cys4&Cys9 bridge); Terlipressin EP Impurity D; Ac-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys4-Cys9); N-Acetyl-glycyl-glycyl-glycyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (4->9)-disulfide; [Ac-Gly1]Terlipressin; Terlipressin Impurity D; N-Terminal acetyl Terlipressin [Ac-TLY]. Grade: ≥95%. Molecular formula: C54H76N16O16S2. Mole weight: 1269.42. | |
| Ac-Gly-BoroPro | A selective FAP inhibitor (Ki= 23 nM). Synonyms: [(2S)-1-(2-acetamidoacetyl)pyrrolidin-2-yl]boronic acid. CAS No. 886992-99-0. Molecular formula: C8H15BN2O4. Mole weight: 214.03. | |
| ACH-000143 | ACH-000143 is a melatonin receptor agonist. Synonyms: ACH 000143; ACH000143. Grade: 98% by HPLC. CAS No. 2225836-30-4. Molecular formula: C13H16ClN3O3. Mole weight: 297.74. | |
| ACH-806 | ACH-806 is a Hepatitis C virus NS3 protein inhibitor. It can inhibit viral RNA replication in HCV replicon cells and is active in genotype 1 HCV-infected patients in a proof-of-concept clinical trial. But Phase-II for Hepatitis C treatment was discontinued. Uses: Hcv. Synonyms: ACH-806; ACH 806; ACH806; GS-9132; GS9132; GS 9132; N-(((4-(pentyloxy)-3-(trifluoromethyl)phenyl)amino)thioxomethyl)-3-Pyridinecarboxamide. Grade: 98%. CAS No. 870142-71-5. Molecular formula: C19H20F3N3O2S. Mole weight: 411.45. | |
| AChE/BChE-IN-1 | AChE/BChE-IN-1 is a potent and brain-penetrant dual inhibitor of Acetylcholinesterase and Butyrylcholinesterase, with IC50s of 1.06 and 7.3 nM for hAChE and hBChE, respectively. AChE/BChE-IN-1 can be used for the research of Alzheimer's disease. CAS No. 2720624-42-8. Molecular formula: C32H35ClN6O3. Mole weight: 587.11. | |
| AChE-IN-3 | AChE-IN-3 has moderate inhibitory activity against AChE and strong NO inhibitory activity with an EC50 of 0.57 μM. Synonyms: AChE-IN-3; 2713548-95-7; EX-A8068; AKOS040757991; MS-27552; HY-145112; CS-0356435. CAS No. 2713548-95-7. Molecular formula: C25H21N3O4. Mole weight: 427.45. | |
| AChE-IN-4 | AChE-IN-4 exhibits the acetylcholine esterase inhibition (AChEI) with an IC50 value of 24.1 μM. Synonyms: AChE-IN-4; HY-145235; CS-0370212. Molecular formula: C32H25BrN6O4S. Mole weight: 669.55. | |
| Ac-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt | Ac-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt. Synonyms: Acetyl-L-histidyl-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide. Molecular formula: C56H81N15O11. Mole weight: 1140.36. | |
| ACHN-975 TFA | ACHN-975 TFA is a selective LpxC inhibitor. It is against a wide range of gram-negative bacteria. Synonyms: (2S)-3-amino-N-hydroxy-2-[(4-{4-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]buta-1,3-diyn-1-yl}phenyl)formamido]-3-methylbutanamide, trifluoroacetic acid. Grade: ≥95%. CAS No. 1410809-37-8. Molecular formula: C22H24F3N3O6. Mole weight: 483.44. | |
| ACHP | ACHP, an IkB kinase inhibitor, has been found to exhibit activities in inducing apoptosis in human myeloma cell lines. Synonyms: 2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile. Grade: ≥97% by HPLC. CAS No. 406208-42-2. Molecular formula: C21H24N4O2. Mole weight: 364.44. | |
| ACI-35 | ACI-35 is a liposome-based vaccine designed to stimulate a patient's immune system to produce antibodies against the misfolded and phosphorylated pathogenic forms of Tau protein. Synonyms: Anti-pTau vaccine - AC Immune. | |
| Ac-Icatibant | Ac-Icatibant is an impurity of Icatibant, which is a selective and specific antagonist of bradykinin B2 receptor. Synonyms: Ac-D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH; Acetyl-D-arginyl-L-arginyl-L-prolyl-L-hydroxyprolyl-glycyl-L-thienylalanyl-L-seryl-D-1,2,3,4-tetrahydroisoquinolyl-L-octahydroindole-L-arginine; L-Arginine, N2-acetyl-D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-(3R)-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-(2S,3aS,7aS)-octahydro-1H-indole-2-carbonyl-. CAS No. 193618-65-4. Molecular formula: C61H91N19O14S. Mole weight: 1346.58. | |
| Aciclovir EP Impurity Q | Aciclovir EP Impurity Q is an impurity of Acyclovir, which is a nucleoside analogue used for the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox. Synonyms: Acyclovir EP Impurity Q (Mixture of Isomers); 2-Amino-9-[[2-(hydroxyethoxy)methoxy]methyl]-1,9-dihydro-6H-purin-6-one and 2-amino-9-[[2-(hydroxymethoxy)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one; Aciclovir Impurity Q. Molecular formula: C9H13N5O4.C9H13N5O4. Mole weight: 510.48. | |
| Aciclovir EP Impurity R | Aciclovir EP Impurity R is an impurity of Acyclovir, which is a nucleoside analogue used for the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox. Synonyms: Acyclovir Formacetal Dimer; 9,9'-(2,5,7,10-Tetraoxaundecane-1,11-diyl)bis(2-amino-9H-purin-6-ol); 9,9'-(2,5,7,10-Tetraoxaundecane-1,11-diyl)bis(2-amino-1H-purin-6(9H)-one); Acyclovir EP Impurity R. Molecular formula: C17H22N10O6. Mole weight: 462.42. | |
| Aciclovir Impurity 1 | Aciclovir Impurity 1 is an impurity of Acyclovir, which is a nucleoside analogue used for the treatment and management of herpes zoster (shingles), genital herpes, and chickenpox. Synonyms: 9-acetyl-2-amino-1,9-dihydro-6H-purin-6-one. CAS No. 1195518-98-9. Molecular formula: C7H7N5O2. Mole weight: 193.16. | |
| Acidic Sophorolipids mix-acetylated | Acidic Sophorolipids mix-acetylated is a compound comprising a combination of acetylated acidic sophorolipids. These lipids are utilized in the biomedical industry for their potential in the development of antibacterial and antifungal drugs. Synonyms: 17-L-[(2'-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-cis-9-octadecenoic acid (6',6"-diacetate). Molecular formula: C30H54O13; C32H56O14; C34H58O15. Mole weight: 622.74; 664.78; 706.82. | |
| Ac-IETD-CHO trifluoroacetate salt | Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM). It inhibits fluticasone propionate-induced increases in apoptosis in peripheral blood T-cells isolated from patients with asthma when used at a concentration 60 μM. Synonyms: Ac-Ile-Glu-Thr-Asp-CHO; Caspase-8 Inhibitor. Grade: ≥95%. CAS No. 191338-86-0. Molecular formula: C21H34N4O10·xCF3COOH. Mole weight: 502.52. | |
| Acifluorfen | Acifluorfen is a protoporphyrinogen oxidase inhibitor and herbicide used to control annual broad-leaved weeds. Synonyms: Acifluorofen. CAS No. 50594-66-6. Molecular formula: C14H7ClF3NO5. Mole weight: 361.65. | |
| Acifran | Acifran is a nicotinic acid receptor agonist with hypolipidemic effects, which shows higher potency than nicotinic acid and clofibrate. It is a potent and full agonist at the human orphan GPCR HM74A/GPR109A and GPR109B. It reduces circulating LDL-cholesterol and serum triglycerides in vivo without affecting liver enzymes or liver weight. Synonyms: AY 25712; AY-25712; AY25712; 4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid; (±)-Acifran; Reductol. Grade: ≥99% by HPLC. CAS No. 72420-38-3. Molecular formula: C12H10O4. Mole weight: 218.21. | |
| Acipimox | Acipimox (trade name Olbetam in Europe) is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion ofVLDL cholesterol, which leads indirectly to a modest reduction in LDL and increase in HDL cholesterol. Synonyms: Acipimox; K-9321; K9321; K 9321; Olbemox; Olbetam. Grade: >98%. CAS No. 51037-30-0. Molecular formula: C6H6N2O3. Mole weight: 154.12. | |
| Acitretin | Acitretin is a second generation retinoid used for psoriasis. Synonyms: Ro 10-1670; Ro-10-1670; Ro10-1670; Ro 10-1670/000; U0279; Acitretin; Soriatane; Etretin; Neotigason. Grade: >98%. CAS No. 55079-83-9. Molecular formula: C21H26O3. Mole weight: 326.43. | |
| Acitretin O-β-D-Glucuronide | Acitretin O-β-D-Glucuronide is a metabolite of the synthetic retinoid Acitretin. Synonyms: 1-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoate β-D-Glucopyranuronic Acid; Isoacitretin Glucuronide; 1-O-[(2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoyl]-beta-D-glucopyranuronic acid. Grade: 95%. CAS No. 99792-36-6. Molecular formula: C27H34O9. Mole weight: 502.55. | |
| Acitretin sodium | Acitretin sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. It can be considered one of the treatments of choice for pustular and erythrodermic psoriasis. However, the efficacy of acitretin sodium as a monotherapy for plaque psoriasis is less, although it is often used in combination therapy with other systemic psoriasis therapies, especially ultraviolet B or psoralen plus ultraviolet A phototherapy, to increase efficacy. Such combination treatments may potentially minimise toxicity by using lower doses of each of the two agent. Synonyms: Ro 10-1670 sodium; Soriatane sodium. Grade: >98%. CAS No. 925701-88-8. Molecular formula: C21H25NaO3. Mole weight: 348.41. | |
| AC-Leu-val-lys-aldehyde | AC-Leu-val-lys-aldehyde showed a stronger inhibition of cathepsin B (IC50 = 4 nM) than leupeptin (IC50 = 0.31 μM). Synonyms: Ac-LVK-aldehyde; (S)-6-Amino-2-[[N-(N-acetyl-L-leucyl)-L-valyl]amino]hexanal. CAS No. 147600-40-6. Molecular formula: C19H36N4O4. Mole weight: 384.51. | |
| Ac-LEVD-CHO trifluoroacetate salt | Ac-LEVD-CHO is a caspase-4 inhibitor. It inhibits IL-1α expression and secretion and caspase-4 activation induced by the T. denticola periodontal pathogen surface protein Td92 in human gingival fibroblasts when used at a concentration of 30 μM. Synonyms: Ac-Leu-Glu-Val-Asp-CHO; Caspase-4 Inhibitor I. Grade: ≥95%. CAS No. 402832-01-3. Molecular formula: C22H36N4O9·xCF3COOH. Mole weight: 500.5. | |
| Aclidinium Bromide | Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). Synonyms: trade name: Eklira Genuair; Tudorza Genuair; Bretaris Genuair. Grade: 0.98. CAS No. 320345-99-1. Molecular formula: C26H30BrNO4S2. Mole weight: 564.553. | |
| Ac-Linaclotide | Ac-Linaclotide is an impurity of Linaclotide, which is a peptide agonist of guanylate cyclase 2C used for the treatment of abdominal pain in patients with irritable bowel syndrome (IBS) associated with constipation. Synonyms: Ac-L-cysteinyl-L-cysteinyl-L-alpha-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-aspargenyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-tyrosine (1-6),(2-10),(5-13)-tris(disulfide); Ac-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH (disulfide bridges between 1-6, 2-10 and 5-13 Cysteines); N-Acetyl-linaclotide; L-Tyrosine, N-acetyl-L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (1→6),(2→10),(5→13)-tris(disulfide). CAS No. 1422389-17-0. Molecular formula: C61H81N15O22S6. Mole weight: 1568.76. | |
| Acolbifene | Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 is the compound having the highest affinity for the estrogen receptor, including estradiol. It has higher affinity for the ER than ICI 182780, hydroxytamoxifen, raloxifene, droloxifene and hydroxytoremifene. EM-652 was also the most potent inhibitor of the percentage of cycling cancer cells. Synonyms: EM-652; SCH 57068; (2S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol. Grade: ≥98%. CAS No. 182167-02-8. Molecular formula: C29H31NO4. Mole weight: 457.57. | |
| Acolbifene hydrochloride | Acolbifene hydrochloride, an active metabolite of EM800, is an orally active selective estrogen receptor modulator (SERM) with anticarcinogenic properties. It has a potent and pure antiestrogenic effect on mammary gland and uterus, and inhibits estradiol (E2)-induced transcriptional activity of ERα and ERβ with IC50s of 2 and 0.4 nM, respectively. Synonyms: EM-652 hydrochloride; SCH 57068 hydrochloride; 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride, (2S)-; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol hydrochloride. Grade: ≥98%. CAS No. 252555-01-4. Molecular formula: C29H32ClNO4. Mole weight: 494.02. | |
| Acotiamide | Acotiamide is a potent and seletive inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide has been approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: Acotiamide; MZ-338; UNII-D42OWK5383. CAS No. 185106-16-5. Molecular formula: C21H30N4O5S. Mole weight: 450.554. | |
| Acotiamide HCl | Acotiamide HCl is the hydrochloride salt of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Synonyms: Acotiamide hydrochloride. CAS No. 185104-11-4. Molecular formula: C21H31ClN4O5S. Mole weight: 487.012. | |
| Acotiamide hydrochloride trihydrate | Acotiamide, also known as YM-443 and Z-338, is a drug approved in Japan for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Uses: Cholinesterase inhibitors. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride trihydrate; YM443; YM-443; YM 443; Z338; Z-338; Z 338; Acotiamide; Acotiamide hydrochloride trihydrate; Brand name: Acofide. Grade: 98%. CAS No. 773092-05-0. Molecular formula: C21H37ClN4O8S. Mole weight: 541.06. | |
| Acotiamide Impurity 10 | An analogue of ACOTIAMIDE. Synonyms: ethyl 2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxylate. Grade: > 95%. CAS No. 738562-93-1. Molecular formula: C20H28N4O5S. HCl. Mole weight: 436.53. | |
| Acotiamide Impurity 5 | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Synonyms: 2-Amino-4-[(2-diisopropylaminoethyl)aminocarbonyl]-1,3-thiazole; 2-amino-N-(2-(diisopropylamino)ethyl)thiazole-4-carboxamide. CAS No. 206882-15-7. Molecular formula: C12H22N4OS. Mole weight: 270.395. | |
| Acotiamide Impurity 6 Maleate | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(2,4,5-trimethoxybenzamido)thiazoleate. CAS No. 185103-81-5. Molecular formula: C26H36N4O9S. Mole weight: 580.653. | |
| Acotiamide Impurity 7 | An analogue of ACOTIAMIDE. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(4-hydroxy-2,5-dimethoxybenzamido)thiazoleate. Grade: > 95%. CAS No. 185105-13-9. Molecular formula: C21H30N4O5S. Mole weight: 450.56. | |
| Acotiamide impurity 8 Maleate | An analogue of ACOTIAMIDE. Synonyms: N-(2-(diisopropylamino)ethyl)-2-(5-hydroxy-2,4-dimethoxybenzamido)thiazoleate. Grade: > 95%. CAS No. 185105-17-3. Molecular formula: C21H30N4O5S. C4H4O4. Mole weight: 566.63. | |
| Acotiamide Impurity 9 | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Synonyms: 4-Thiazolecarboxamide, 2-amino-N-(2-aminoethyl); 2-amino-N-(2-aminoethyl)-1,3-thiazole-4-carboxamide. CAS No. 948053-83-6. Molecular formula: C6H10N4OS. Mole weight: 186.24. | |
| Acotiamide Related Compound 12 | An impurity of Acotiamide, a drug for the treatment of postprandial fullness, upper abdominal bloating, and early satiation due to functional dyspepsia. Synonyms: 2-[N-(2,4,5-Trimethoxybenzoyl)amino]-4-(ethoxycarbonyl)-1,3-thiazole; Ethyl 2-(2,4,5-trimethoxybenzamido)thiazole-4-carboxylate. CAS No. 185105-98-0. Molecular formula: C16H18N2O6S. Mole weight: 366.388. | |
| Acotiamide related compound 4 | An analogue of ACOTIAMIDE. Synonyms: 1-(chloromethyl)-2,4,5-trimethoxybenzene. Grade: > 95%. CAS No. 53811-44-2. Molecular formula: C10H13ClO3. Mole weight: 216.67. | |
| Ac-Oxytocin | Ac-Oxytocin is an impurity of Oxytocin, which is a mammalian neurohypophysial hormone used as a vasodilator agent. Synonyms: N2.1-Acetyloxytocin; Acetyl-L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparginyl-L-cystyl-L-leucyl-L-prolyl-L-glycinamide (disulfide bridge between cysteines); Cys(Ac)-Oxytocin; Ac-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Oxytocin, N-acetyl-; N(alpha)-Acetyloxytocin; N-Acetyloxytocin; Oxytocin, 1-(N-acetylcysteine); Oxytocin EP Impurity E; Ac-CYIQNCPLG-NH2(Cys1&Cys6 bridge). Grade: ≥95%. CAS No. 10551-48-1. Molecular formula: C45H68N12O13S2. Mole weight: 1049.23. | |
| ACP-105 | ACP-105 is an orally available androgen receptor modulator (SARM). It binds to androgen receptors in muscles and bones providing anabolic effect. CAS No. 899821-23-9. Molecular formula: C16H19ClN2O. Mole weight: 290.79. | |
| ACP-5862 | ACP-5862 is a metabolite of Acalabrutinib, a second-generation BTK inhibitor used as a medication indicated for the treatment of non-Hodgkin lymphoma known as mantle cell lymphoma. Synonyms: ACP 5862; ACP5862. CAS No. 2230757-47-6. Molecular formula: C26H23N7O3. Mole weight: 481.52. | |
| ACPT-I | ACPT-I, a competitive antagonist for mGluRs, has been found to exhibit anticonvulsant activities. Synonyms: ACPT-1; ACPT 1; ACPT1; (1S,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid. Grade: ≥98% by HPLC. CAS No. 194918-76-8. Molecular formula: C8H11NO6. Mole weight: 217.18. | |
| ACPT-II | ACPT-II has been found to be a mGluR antagonist and could probably exhibit neuroprotective effects. Synonyms: (1R,3R,4S)-1-Aminocyclopentane-1,3,4-tricarboxylic acid. Grade: ≥98% by HPLC. CAS No. 195209-04-2. Molecular formula: C8H11NO6. Mole weight: 217.18. | |
| ACP-TMP | ACP-TMP is a derivative of Trimethoprim, which inhibits the enzyme dihydrofolate reductase. Synonyms: 3-Chloro-N-(17-(4-((2,4-diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenoxy)-15-oxo-4,7,10-trioxa-14-azaheptadecyl)-4-((2-(2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)propanamido)ethyl)thio)benzamide; Acp-tmp. Molecular formula: C45H58ClF3N8O11S2. Mole weight: 1043.57. | |
| ACR 16 hydrochloride | ACR 16 hydrochloride is a dopaminergic stabilizer (Ki values 17550 nM and 7521 for D2(low) and D2(high), respectively) that state-dependently stabilizes psychomotor activity by the dual actions of functional dopamine D2 receptor antagonism and strengthening of cortical glutamate functions in various settings of perturbed neurotransmission. ACR 16 hydrochloride is used for ameliorating several neurological and psychiatric disorders, including Huntington's disease. Uses: The treatment of neurological and psychiatric disorders. Synonyms: ACR 16 hydrochloride; ACR16 hydrochloride; ACR-16 hydrochloride; Pridopidine Hydrochloride; 4-(3-methylsulfonylphenyl)-1-propylpiperidine hydrochloride. Grade: 99%. CAS No. 882737-42-0. Molecular formula: C15H23NO2S.HCl. Mole weight: 317.87. | |
| Ac-rC(5-Me) Phosphoramidite | Ac-rC(5-Me) Phosphoramidite: a highly specialized chemical reagent, meticulously crafted for the intricacies of solid-phase synthesis of modified RNA molecules. With its unique capability for integrating 5-methylcytosine into RNA strands, Ac-rC(5-Me) Phosphoramidite is the go-to tool for researchers seeking to investigate the complex dynamics of RNA stability and epigenetic regulation. Amplify your understanding of the intricate interplay of biochemical systems with the expertly designed, scientifically rigorous Ac-rC(5-Me) Phosphoramidite. Synonyms: DMT-2'-O-TBDMS-5-methyl-rC(ac) Phosphoramidite; N-Acetyl-5-methyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2'-O-(tert-Butyldimethylsilyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-N4-acetyl-5-methylcytidine. Molecular formula: C48H66N5O9PSi. Mole weight: 916.14. | |
| Ac-rC Phosphoramidite | Ac-rC Phosphoramidite is a commonly used protected 2-OTBDMS phosphoramidite for incorporating cytidine nucleotides into synthetic oligonucleotides. Synonyms: N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]cytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine 3'-CE phosphoramiditee; 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl-2'-O-t-butyldimethylsilylcytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite; DMT-2'-O-TBDMS-rC(ac) Phosphoramidite; 2'-TBDMS-Ac-rC-CE-Phosphoramidite; 5'-DMT-2'-O-TBDMS-N4-Acetyl-Cytidine Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 121058-88-6. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11. | |
| Acremin F | Acremine F is a fungal metabolite originally isolated from Acremonium byssoides. Synonyms: Acremine F. Grade: ≥95%. CAS No. 863480-61-9. Molecular formula: C12H20O4. Mole weight: 228.28. | |
| Acremin I | Acremine I is a fungal metabolite which has been found in Acremonium. It inhibits germination of P. viticola sporangia by 23.2 and 32.8% when used at concentrations of 0.5 and 1 mM, respectively. Synonyms: Acremine I. Grade: ≥95%. CAS No. 1110661-29-4. Molecular formula: C12H16O5. Mole weight: 240.25. | |
| Acremonidin A | Acremonidins A to approximately E (1 to approximately 5) were produced by fermentation of Acremonium sp. LL-Cyan 416, in heterogeneous phases. Acremonidins A showed moderate activity against Gram-positive bacteria, including the methicillin-resistant staphylococci and vancomycin-resistant enterococci. Molecular formula: C33H26O12. Mole weight: 614.56. | |
| Acremoxanthone C | Acremoxanthone C, a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum, binds to the human calmodulin (hCaM) biosensor hCaM M124C-MBBR with a Kd of 18.25 nM. Synonyms: 17aH-8a,16-Ethenonaphtho[2',3':5,6]cyclohepta[1,2-c]xanthene-17a-carboxylic acid, 9-(acetyloxy)-1,5,8,9,15,16-hexahydro-1,4,6,13,14-pentahydroxy-11-methyl-5,15-dioxo-, methyl ester, (1R,8aR,9S,16S,17aR)-. CAS No. 1360445-63-1. Molecular formula: C33H26O12. Mole weight: 614.55. | |
| Acridine | Acridine is a quinoline derivative ever used as an industrial dye. Some of acridines exhibits an antiseptic activity. Uses: Industrial dyes. Synonyms: 10-Azaanthracene; 2,3-Benzoquinoline; 9-Azaanthracene; Benzo[b]quinoline; Dibenzo[b,e]pyridine; NSC 3408. CAS No. 260-94-6. Molecular formula: C13H9N. Mole weight: 179.22. | |
| Acridine CE Phosphoramidite | Acridine CE Phosphoramidite is an essential building block for the synthesis of modified oligonucleotides used in biomedical research. It enables the labeling and detection of DNA fragments, as well as the treatment of viral infections and cancer. Grade: >95% by HPLC. Molecular formula: C51H60CIN4O6P. Mole weight: 891.49. | |
| Acridine Phosphoramidite | Acridine Phosphoramidite, a versatile compound used for the synthesis of nucleic acids, has been employed in the development of antisense oligonucleotides to tackle a range of diseases such as cancer, viral infections and genetic disorders. It functions as a phosphoramidite building block for oligonucleotide synthesis, and is available in liquid or solid form, with different quantities purchasable for research objectives. Synonyms: 1-Dimethoxytrityloxy-2-(N-acridinyl-4-aminobutyl)-propyl-3-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite. Molecular formula: C51H60N4O6PCl. Mole weight: 891.53. | |
| Acriflavine | Acriflavine is an anti-infective agent including 3,6-diamino-10-methylacridinium chloride and 3,6-diaminoacridine in an approx. 2:1 ratio, the ratio increasing with increasing acidity. Uses: Intercalating agents. Synonyms: Acriflavin; Flavacridine; Fungus Cure; Triphaflavine; 3,6-diamino-10-methylacridinium chloride mix. with 3,6-diaminoacridine. Grade: ≥95%. CAS No. 65589-70-0. Molecular formula: C27H25ClN6. Mole weight: 468.99. | |
| Acrivastine | Acrivastine, also known as BW825C, is an antihistamine with peripheral H1-antagonist potency equal to that of triprolidine for the treatment of allergic rhinitis. Synonyms: (E)-3-[6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridin-2-yl]prop-2-enoic acid; acrivastine; BW 825C; BW-825C; BW825C; Glaxo Wellcome brand of acrivastine; GlaxoSmithKline brand of acrivastine; Semprex. CAS No. 87848-99-5. Molecular formula: C22H24N2O2. Mole weight: 348.44. | |
| Acroteben | Acroteben is a bio-active chemical but no detailed information has been published yet. Synonyms: BRN 0199526; BRN0199526; BRN-0199526; UNII-4DAE97DDEP; AT-2; N-[(E)-(3-hydroxyphenyl)methylideneamino]pyridine-4-carboxamide. Grade: 98%. CAS No. 840-80-2. Molecular formula: C13H11N3O2. Mole weight: 241.25. | |
| Acrylamide-1,2,3-13C3 | Acrylamide-1,2,3-13C3 is a labelled Acrylamide. Acrylamide is commonly used to manufacture various polymers. Synonyms: Acrylamide-1,2,3-13C3. Grade: 95% by HPLC; 98% atom 13C. CAS No. 287399-26-2. Molecular formula: 13C3H5NO. Mole weight: 74.06. | |
| Ac-RYYRIK-NH2 TFA | Ac-RYYRIK-NH2 TFA is a potent and partial agonist on ORL1 transfected in CHO cells (Kd = 1.5 nM). Ac-RYYRIK-NH2 is a specific antagonist for the activation of G protein and competitively antagonizes the stimulation of [35S]-GTPgS binding to G proteins by nociceptin/orphanin FQ (noc/OFQ) in membranes and sections of rat brain. Grade: 98%. Molecular formula: C46H71F3N14O11. Mole weight: 1053.13. | |
| ACS 67 | ACS 67 is an analog of latanoprost that contains a hydrogen sulfide releasing component conjugated to the latanoprost carboxyl group. Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug for the treatment of glaucoma. Synonyms: [4-(5-sulfanylidenedithiol-3-yl)phenyl] (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate. Grade: ≥95%. CAS No. 1088434-86-9. Molecular formula: C32H38O5S3. Mole weight: 598.8. | |
| ACSS2-IN-1 | ACSS2-IN-1 is a potent ACSS2 inhibitor used in the treatment of cancer. Synonyms: ACSS2-IN-1|CHEMBL4846168|BDBM50574370|HY-145392|CS-0372824. Grade: ≥98% (HPLC). CAS No. 2711039-08-4. Molecular formula: C27H25ClN6O2. Mole weight: 500.98. | |
| ACT001 | ACT001, a fumarate salt form of DMAMCL (a prodrug of Micheliolide), can cross the blood-brain barrier. ACT001 is an orally active PAI-1 inhibitor that inhibits the phosphorylation of PI3K and AKT. ACT001 has potent anti-glioblastoma (GBM) activity and immunomodulatory effects. Grade: 98%. CAS No. 1582289-91-5. Molecular formula: C21H31NO7. Mole weight: 409.47. | |
| ACT-001 | ACT001 is a PAI-1 inhibitor. ACT001 directly binds PAI-1 to inhibit the PI3K/AKT pathway, which induces the inhibition of glioma cell proliferation, invasion and migration. Synonyms: Dimethylaminomicheliolide; DMAMCL; (3R,3aS,9R,9aS,9bS,Z)-3-((Dimethylamino)methyl)-9-hydroxy-6,9-dimethyl-3,3a,4,5,7,8,9,9a-octahydroazuleno[4,5-b]furan-2(9bH)-one. Grade: 99%. CAS No. 1403357-81-2. Molecular formula: C17H27NO3. Mole weight: 293.40. | |
| ACT 178882 | ACT 178882 is a novel Renin inhibitor (IC50= 1.4 nM). Synonyms: ACT 178882, ACT-178882, ACT178882; MK-1597; MK1597; MK 1597; (3R,4S)-N-[[2-chloro-5-(2-methoxyethyl)phenyl]methyl]-N-cyclopropyl-4-[6-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]pyridin-3-yl]piperidine-3-carboxamide. CAS No. 1007392-69-9. Molecular formula: C33H38Cl3N3O4. Mole weight: 647.03. | |
| ACT-246475 | This active molecular is a reversible and selective platelet P2Y12 receptor antagonist. IC50 value of ACT-246475 is 8.0 nM. ACT-246475 dose-dependently blocked thrombus formation in the rat ferric chloride model and displayed a wide therapeutic window. In May 2016, Phase-I development is ongoing in France. Uses: Cardiovascular disorders. Synonyms: ACT-246475; ACT 246475; ACT246475; Selatogrel. ((R)-3-(4-(butoxycarbonyl)piperazin-1-yl)-2-(6-((S)-3-methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxamido)-3-oxopropyl)phosphonic acid. Grade: 98%. CAS No. 1159500-34-1. Molecular formula: C28H39N6O8P. Mole weight: 618.62. | |
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