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(R)-3-Aminohex-5-enoic acid
Synonyms: D-β-Homoallylglycine; D-β-HomoGly(allyl)-OH; (R)-3-Amino-5-hexenoic acid. Grades: ≥ 98% by HPLC. CAS No. 82448-92-8. Molecular formula: C6H11NO2. Mole weight: 129.16.
Rabelomycin is originally isolated from Str.olivaceus. Rabelomycin only works against gram-positive bacteria. Synonyms: ZINC4654730. Molecular formula: C19H14O6. Mole weight: 338.31.
Racemomycin A
It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin F; Yazumycin A; Streptothricin VI; Antibiotic S 15-1A; BRN 6031385; 2-((O-(Aminocarbonyl)-2-deoxy-2-((3,6-diamino-1-oxohexyl)amino)-beta-D-gulopyranosyl)amino)-1,3,5,6,7,7a-hexahydro-7-hydroxy-4H-imidazo(4,5-c)pyridin-4-one. Grades: >98%. CAS No. 3808-42-2. Molecular formula: C19H34N8O8. Mole weight: 502.52.
Racemomycin B
It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin D; Antibiotic OP 2C; 2-{ [ (3S) -3-amino-6-{ [ (3S) -3-amino-6-{ [ (3S) -3, 6-diaminohexanoyl] amino}hexanoyl] amino}hexanoyl] amino}-4-O-carbamoyl-2-deoxy-N- [ (3aS, 7R, 7aS) -7-hydroxy-4-oxooctahydro-2H-imidazo [4, 5-c] pyridin-2-ylidene] -beta-D-gulopyranosylamine. Grades: >98%. CAS No. 3776-37-2. Molecular formula: C31H58N12O10. Mole weight: 758.86.
Racemomycin C
It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin E; Yazumycin C; Antibiotic S 15-1B; 2-((O-(Aminocarbonyl)-2-((3-amino-6-((3,6-diamino-1-oxohexyl)amino)-1-oxohexyl)amino)-2-deoxy-beta-D-gulopyranosyl)amino)-1,3a,5,6,7,7a-hexahydro-7-hydroxy-4H-imidazo(4,5-c)pyridin-4-one; BRN 4286375. CAS No. 3776-38-3. Molecular formula: C25H46N10O9. Mole weight: 630.69.
Racemomycin D
It is produced by the strain of Str. racemochromogenes 229. It has broad spectrum antibacterial activity and antifungal effect, and it can inhibit PR-8 of influenza virus in tissue culture. Synonyms: Streptothricin C; Antibiotic OP 2D. CAS No. 3776-36-1. Molecular formula: C37H70N14O11. Mole weight: 887.04.
Racemomycin E
Racemomycin E is an N-glycoside antibiotic produced by various bacteria such as Streptomyces lavendulae. It has anti-gram-positive bacteria, negative bacteria, mycobacteria and anti-fungal activity. Synonyms: Streptothricin B; A 53930C. CAS No. 3484-68-2. Molecular formula: C43H82N16O12. Mole weight: 1015.21.
Radicinin
Radicinin is produced by the strain of Curvularia lunata IAM-18010. It has anti-bacterial effect, but its activity is weak. Synonyms: Stemphylone; NSC 118343; 2,3-Dihydro-3-alpha-hydroxy-2-beta-methyl-7-propenyl-4H,5H-pyrano(4,3-b)pyran-4,5-dione. CAS No. 10088-95-6. Molecular formula: C12H12O5. Mole weight: 236.22.
Rakicidin A
Rakicidin A is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 40 μg/mL. Molecular formula: C32H54N4O7. Mole weight: 606.79.
Rakicidin B
Rakicidin B is originally isolated from Micromonospora sp. R385-2. It has anti-tumor activity in vitro with the IC50 of 200 μg/mL. Molecular formula: C33H56N4O7. Mole weight: 620.82.
Ramage Linker
Ramage Linker, also known as Ramage-Linker can be used for preparation of peptide amides specially as an acid-labile peptide amide linker. Synonyms: Fmoc-suberol; 2-[[5-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-2-yl]oxy]acetic Acid; (R,S)-2-[[5-(9-FLUORENYLMETHYLOXYCARBONYLAMINO)-DIBENZO[A,D]CYCLOHEPTANE-2-YL]OXY]-ACETIC ACID; 5-FMoc-aMino-2-carboxyMethoxy-10,11-dihydro-5H-dibenzo[a,d]cycloheptene; Fmoc-Suberol; 5-FMOC-AMINO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTENE-2-HYDROXY ACETIC ACID; REF DUPL: Ramage Linker,Fmoc-Suberol. Grades: 98% (HPLC). CAS No. 212783-75-0. Molecular formula: C32H27NO5. Mole weight: 505.56.
Ramulosin
It is produced by the strain of Pestalotia ramulosa NRRL 2826. Ramulosin has an antifungal effect and inhibits the germination of fungal meristems. Synonyms: Ramulosine; NSC-112906; Ramulosin, (+)-; (3S,4AR)-8-hydroxy-3-methyl-3,4,4A,5,6, 7-hexahydro-1h-isochromen-1-one. CAS No. 29914-01-0. Molecular formula: C10H14O3. Mole weight: 182.22.
Rancinamycin III
Rancinamycin III is an antibiotic that has antibacterial properties originally isolated from Str. lincolnensis. Synonyms: SCHEMBL16431322. Grades: >97%. CAS No. 60925-60-2. Molecular formula: C7H10O5. Mole weight: 174.15.
Rasfonin
Rasfonin is a fungal metabolite that has been found in Talaromyces sp. 3656-A1. It is a Ras-dependent apoptosis inducer that induces apoptosis in Ras-dependent cells such as Ba/F3-V12 cells. Synonyms: (-)-Rasfonin; (2E,4E,6S)-8-hydroxy-6-(hydroxymethyl)-4-methyl-2,4-octadienoic acid, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester. Grades: >95%. CAS No. 303156-68-5. Molecular formula: C25H38O6. Mole weight: 434.56.
Rat CGRP-(8-37)
CGRP 8-37 (rat) is a peptide antagonist for CGRP1 receptors. Synonyms: Calcitonin Gene-Related Peptide 8-37 (rat); 8-37-a-Calcitoningene-related peptide (human reduced), 25-L-aspartic acid, 35-L-glutamic acid-; Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; CGRP 8-37 rat; L-valyl-L-threonyl-L-histidyl-L-arginyl-L-leucyl-L-alanyl-glycyl-L-leucyl-L-leucyl-L-seryl-L-arginyl-L-seryl-glycyl-glycyl-L-valyl-L-valyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-phenylalanyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grades: ≥95%. CAS No. 129121-73-9. Molecular formula: C138H224N42O41. Mole weight: 3127.51.
Rebeccamycin
Rebeccamycin, an antitumor antibiotic, inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I and has negligible effect on protein kinase C and topoisomerase II. Synonyms: 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-beta-D-glucopyranosyl)-; 1,11-dichloro-12-(4-O-methyl-beta-D-glucopyranosyl)-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione; (Rebeccamycin)1,11-dichloro-12-(3,4-dihydroxy-6-hydroxymethyl-5-methoxytetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; 1,11-dichloro-12-(3,4-dihydroxy-6-hydroxymethyl-5-methoxytetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; 1,11-dichloro-12-(3,4-dihydroxy-6-hydroxymethyl-5-methoxytetrahydro-2H-2-pyranyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione(rebeccamycin); 1,11-dichloro-12-[3,4-dihydroxy-6-hydroxymethyl-5-methoxy-(2R,3R,4S,5R,6R)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione; dichloro-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxy-tetrahydropyran-2-yl][?]dione. Grades: >98.0%. CAS No. 93908-02-2. Molecular formula: C27H21Cl2N3O7. Mole weight: 570.38.
Reblastatin
Reblastatin is an Ansa antibiotic produced by Streptomyces hygroscopicus subsp. hygroscopicus SANK 61995 and is a reduction product of Geldanamycin. It is a cell cycle inhibitor that can inhibit cell proliferation. The IC50 for human mesenchymal lymphoma U-93 is 0.43 μg/mL, and the reference geldanamycin is 0.0011 μg/mL. Molecular formula: C29H44N2O8. Mole weight: 548.67.
RES-1149-1
RES-1149-1 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 1.5 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5.
RES-1149-2
RES-1149-2 is an endothelin type B receptor antagonist produced by Aspergillus sp. RE-1149. It selectively inhibits the ET-1 binding to endothelin type B receptor with IC50 value of 20 μmol/L. Molecular formula: C23H30O5. Mole weight: 386.5.
RES-1214-1
RES-1214-1 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 1.5 μmol/L. Molecular formula: C17H16O8. Mole weight: 348.3.
RES-1214-2
RES-1214-2 is an endothelin type A receptor antagonist produced by Pestalotiopsis sp. RE-1214. It selectively inhibits the ET-1 binding to endothelin type A receptor with IC50 value of 20 μmol/L. Molecular formula: C17H15ClO8. Mole weight: 382.7.
RES-701-1
RES-701-1 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Uses: Endothelin receptor antagonists. Synonyms: GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP; GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH; CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP). Grades: 95%. CAS No. 151308-34-8. Molecular formula: C103H115N23O23. Mole weight: 2043.16.
RES-701-2
RES-701-2 is an endothelin type B receptor antagonist produced by Streptomyces sp. RE-701. It selectively inhibits the ET-1 binding to endothelin type B receptor. Molecular formula: C103H115N23O24. Mole weight: 2059.15.
Reserpiline
Reserpiline is an indole alkaloid that has been found in R. tetraphylla. It is an antipsychotic, antiparasitic and hypotensive agent. Synonyms: Methyl (3beta,19alpha,20alpha)-16,17-didehydro-10,11-dimethoxy-19-methyloxayohimban-16-carboxylate; Elliptamine; Reserpilin; (-)-Reserpiline; (4S,4aS,13bR,14aS)-4a,5,7,8,13,13b,14,14a-octahydro-10,11-dimethoxy-4-methyl-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylic acid, methyl ester; methyl (4S,4aS,13bR,14aS)-10,11-dimethoxy-4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate. Grades: >95% by HPLC. CAS No. 131-02-2. Molecular formula: C23H28N2O5. Mole weight: 412.48.
Resistoflavine
A rare, boat-shaped, pentacyclic polyketide isolated from several species of streptomyces; exhibits weak antibacterial activity against gram-positive and gram-negative bacteria; exhibits potent cytotoxic activity against tumour cell lines in vitro; inhibits growth, and nucleic acid and protein synthesis in bacillus subtilis. Synonyms: Resistoflavin; BRN 2491848; (-)-3,5,7,11b-Tetrahydroxy-1,1,9-trimethyl-2H-benzo(cd)pyrene-2,6,10(1H,11bH)-trione. Grades: >98% by HPLC. CAS No. 29706-96-5. Molecular formula: C22H16O7. Mole weight: 392.36.
Resomycin A
It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin A showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H18O7. Mole weight: 382.36.
Resomycin B
It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin B showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H16O6. Mole weight: 364.35.
Resomycin C
It is produced by the strain of Streptomyces sp. GW71/2497. Resomycin C showed activity of anti-staphylococcus aureus, Escherichia coli and Streptomyces green, with MIC of about 20 μg/mL. Molecular formula: C21H14O6. Mole weight: 362.33.
Resorcinomycin B
Resorcinomycin B is originally isolated from Streptoverticillum roseoverticillatum. Synonyms: N-(alpha-Guanidino-3,5-dihydroxy-4-ethylphenylacetyl)glycine. CAS No. 100234-69-3. Molecular formula: C13H18N4O5. Mole weight: 310.31.
Resormycin
It is originally isolated from Str. platensis MJ953-SF5. It has a strong herbicide effect, especially on the seeds of dicotyledonous plants. Resormycin also has anti-fungal action, resisting some plant pathogenic fungi, but not resisting bacteria and yeast. Molecular formula: C21H31ClN4O7. Mole weight: 486.95.
Resorthiomycin
It is produced by the strain of Str. collinus 45H6 and it can inhibit L5178Y of leukemia cells in vitro. Synonyms: 6-Acetyl-4-(3-hydroxybutyl)-2-methyl-5-methylthioresorcinol. CAS No. 126651-92-1. Molecular formula: C14H20O4S. Mole weight: 284.37.
Respinomycin A1
Respinomycin A1 is produced by the strain of Str. xanthocidicus RK-483 and it causes the differentiation of leukemic K-562 cells. Synonyms: 13-[(6-Deoxy-3-C-methyl-2-O-methylhexopyranosyl)oxy]-23-(dimethylamino)-11, 15, 22-trihydroxy-12-methoxy-1, 11-dimethyl-6, 17-dioxo-20, 25-dioxahexacyclo[19.3.1.02, 19.05, 18.07, 16.09, 14]pentacosa-2, 4,7(16),8,14,18-hexaen-24-yl 3-amino-2,3,6-trideoxy-4-O-(6-deoxy-3-C-methyl-2-O-methylhexopyranosyl)-3-methylhexopyranoside. Grades: >99%. CAS No. 138843-19-3. Molecular formula: C51H72N2O20. Mole weight: 1033.12.
Respinomycin A2
Respinomycin A2 is produced by the strain of Str. xanthocidicus RK-483 and it causes the differentiation of leukemic K-562 cells. Synonyms: 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-9,16-dione, 3,4,5,6,11,12,13,14-octahydro-5-((3-amino-2,3,6-trideoxy-4-O-(6-deoxy-3-C-methyl-2-O-methyl-alpha-mannopyranosyl)-3-C-methyl-beta-ribo-hexopyranosyl)oxy)-6,12-dimethyl-4-(dimethylamino)-13-methoxy-3,12,15-trihydroxy-, (2-alpha,3-beta,4-alpha,5-alpha,6-alpha,12-beta,13-alpha)-(+)-. CAS No. 151233-04-4. Molecular formula: C43H58N2O15. Mole weight: 842.92.
Reticulol
An isocoumarin metabolite produced by selected species of streptomyces. It is a potent inhibitor of cyclic nucleotide phosphodiesterase. It also causes dose-dependent inhibition of lung metastasis in the B16F10 melanoma model. Synonyms: 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin; 6,8-Dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one; K 251-1; NSC 294978. Grades: >95% by HPLC. CAS No. 26246-41-3. Molecular formula: C11H10O5. Mole weight: 222.19.
Reumycin
It is originally isolated from Act. sp. Reumycin is toxic to Airy carcinoma, sarcoma-180, sarcoma-37, lymphosarcoma and other tumor cells. Synonyms: Reumitsin; Rheumygin; 1-demethyltoxoflavin; NSC 99733; 6-Methylpyrimido(5,4-e)-as-triazine-5,7(1H,6H)-dione. CAS No. 5016-18-2. Molecular formula: C6H5N5O2. Mole weight: 179.14.
Reveromycin A
The dominant analogue of complex of spiroketals isolated from streptomyces sp. It is an inhibitor of the mitogenic activity of EGF and a G1 phase cell cycle inhibitor. It selectively inhibits isoleucyl-trna synthetase. It has anti-proliferation effect on human cell lines KB and K562, and has potent antifungal activity. Synonyms: (-)-Reveromycin A; [2S-[2α(1E, 3E), 3β, 6α[8S*(2E, 4E, 6R*, 7R*, 8E), 9R*]]]-butanedioic acid mono[3-butyl-8-(9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl)-2-(4-carboxy-3-methyl-1,3-butadienyl)-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester; Butanedioic Acid Mono[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrienyl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] Ester. Grades: >99% by HPLC. CAS No. 134615-37-5. Molecular formula: C36H52O11. Mole weight: 660.79.
Reveromycin B
Reveromycin B is a polyketide antibiotic isolated from Streptomyces, which can inhibit mitotic activity. Synonyms: BDBM50217842; ZINC49871994. Grades: >98% by HPLC. CAS No. 144860-68-4. Molecular formula: C36H52O11. Mole weight: 660.79.
Reveromycin C
Reveromycin C is a polyketide isolated from Streptomyces. It is an antibiotic inhibitor with mitotic activity that responds to EGF. Grades: >95% by HPLC. CAS No. 144860-69-5. Molecular formula: C37H54O11. Mole weight: 674.82.
Reveromycin D
Reveromycin D is a bacterial metabolite isolated from Streptomyces. It inhibits EGF-induced mitotic activity in Balb/MK cells and has pH-dependent antifungal activity against Candida albicans. Grades: >95% by HPLC. CAS No. 144860-70-8. Molecular formula: C37H54O11. Mole weight: 674.82.
Rhizoxin
Rhizoxin is an antitumor antibiotic produced by Rhizopus sp. No. F-1360. It was highly active against leukemia L1210 and melanoma B16. Synonyms: Antibiotic WF-1360; WF-1360. Grades: >98%. CAS No. 90996-54-6. Molecular formula: C35H47NO9. Mole weight: 625.7.
Rhodirubin A
It is produced by the strain of Str. sp. ME505-HE1. Rhodirubin A has a strong anti-gram-positive bacteria effect, and also has an effect on Mycobacterium. It can also prolong the survival time of mice inoculated with leukemia L-1210. Synonyms: 1-Hydroxy-MA-144-N1; MA144 N2; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-4-0-(2,6-dideoxy-4-O-((2S-(2-alpha,5-beta,6-beta))-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 64253-73-2. Molecular formula: C42H55NO16. Mole weight: 829.88.
Rhodirubin B
It is produced by the strain of Str. sp. ME505-HE1. Rhodirubin B has a strong anti-gram-positive bacteria effect, and also has an effect on Mycobacterium. It can also prolong the survival time of mice inoculated with leukemia L-1210. Synonyms: 1-Naphthacenecarboxylic acid, 1,2,3,4,6,11-hexahydro-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-4-O-((2S-(2-alpha,5-beta(2R*,5R*,6R*),6-beta))-tetrahydro-6-methyl-5-((tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)oxy)-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-. CAS No. 64502-82-5. Molecular formula: C42H55NO15. Mole weight: 813.88.
Rhodomycin
Rhodomycin are a family of antibiotics produced by a red-pigmented mutant of Streptomyces griseus. They possess anti-gram-positive bacteria, anti-gram-negative bacteria and antifungal properties. Synonyms: Epsilon-Rhodomycin. CAS No. 1401-16-7.
Rhodomycin A
Rhodomycin A is originally isolated from Str. purpurascens 340. It has the activity of anti-gram-positive bacteria and weak effect on anti-gram-negative bacteria and fungi. Synonyms: beta-Rhodomycin II; NSC-136044; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R,8R,10S)-. CAS No. 23666-50-4. Molecular formula: C36H48N2O12. Mole weight: 700.77.
Rhodomycin B
Rhodomycin B is originally isolated from Str. purpurascens 340. It has the activity of anti-gram-positive bacteria and weak effect on anti-gram-negative bacteria and fungi. Synonyms: beta-Rhodomycin I; Betaclamycin T; BRN 0073612. Grades: ≥95%. CAS No. 1404-52-0. Molecular formula: C28H33NO10. Mole weight: 543.56.
Rhodopeptin C1
Rhodopeptin C1 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively. Synonyms: (3S,6S)-6-(3-aminopropyl)-3-isopropyl-13-(7-methylnonyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetrone. Molecular formula: C25H47N5O4. Mole weight: 481.67.
Rhodopeptin C2
Rhodopeptin C2 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively. Synonyms: (3S,6S)-6-(3-aminopropyl)-13-(7-methylnonyl)-3-sec-butyl-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetrone. Molecular formula: C26H49N5O4. Mole weight: 495.70.
Rhodopeptin C3
Rhodopeptin C3 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively. Synonyms: (3S,6S)-6-(3-aminopropyl)-3-isopropyl-13-(9-methyldecyl)-1,4,7,10-tetrazacyclotridecane-2,5,8,11-tetrone. Molecular formula: C26H49N5O4. Mole weight: 495.70.
Ribostamycin is an antibiotic produced by Streptomyces ribosidifcus. It is active against gram-positive bacteria. Synonyms: Vistamycin; Hetangmycin; Xylostatin; Antibiotic SF 733; SF-733; SF 733. Grades: 95%. CAS No. 25546-65-0. Molecular formula: C17H34N4O10. Mole weight: 454.47.
Ribostamycin sulfate
Ribostamycin is an aminoglycoside antibiotic, containing a neutral sugar moiety, and is produced by Streptomyces ribosidificus. Synonyms: Vistamycin Sulfate; Landamycine; Ribomycine. Grades: >98%. CAS No. 53797-35-6. Molecular formula: C17H36N4O14S. Mole weight: 552.55.
Ridaforolimus
Ridaforolimus is a small molecule and non-prodrug analogue of the lipophilic macrolide antibiotic rapamycin with potential antitumor activity. Ridaforolimus binds to and inhibits the mammalian target of rapamycin (mTOR), which may result in cell cycle arrest and, consequently, the inhibition of tumor cell growth and proliferation. Upregulated in some tumors, mTOR is a serine/threonine kinase involved in regulating cellular proliferation, motility, and survival that is located downstream of the PI3K/Akt signaling pathway. Synonyms: AP23573; AP 23573; AP-23573; MK8669; MK 8669; MK-8669; Deforolimus. Grades: >95% by HPLC. CAS No. 572924-54-0. Molecular formula: C53H84NO14P. Mole weight: 990.20.
Rifampicin
It is a semi-synthetic antibiotic of the rifamycin group. It is an inhibitor of bacterial RNA polymerase and has antibacerial activity. Uses: Antibiotics, antitubercular; enzyme inhibitors; leprostatic agents; nucleic acid synthesis inhibitors. Synonyms: Rimactane; 3-[[(4-Methyl-1-piperazin-yl)imino]methyl]rifamycin; Abrifam; Eremfat; Famcin; NSC 113926; Rifa; Rifacap; Rifadin; Rifadine; Rifaldazine; Rifampicin SV; Rifamycin AMP; Rifaprodin; Rifoldin; Riforal; Rimactan; Rimactane; Rimapen; Sinerdol; Tubocin. Grades: 95% by HPLC. CAS No. 13292-46-1. Molecular formula: C43H58N4O12. Mole weight: 822.94.
Rifamycin B
Cas No. 13929-35-6.
Rifamycin L
Rifamycin L is produced by the strain of Amycolatopsis mediterranei ME/83. It has the antibacterial action of rifamycin. Synonyms: Rifamycin, 4-(hydroxyacetate). Grades: >98%. CAS No. 26117-02-2. Molecular formula: C39H49NO14. Mole weight: 755.80.
Rifamycin SV
Cas No. 6998-60-3.
Rifamycin W
Rifamycin W is originally isolated from Amycolatopsis mediterranei ME/83. It has anti-gram-positive bacterial activity. CAS No. 53904-81-7. Molecular formula: C35H45NO11. Mole weight: 655.73.
Rimocidin
It is originally isolated from Str. rimosus and it has antifungal and protozoan effects. Synonyms: Rimocidine. Grades: >98%. CAS No. 1393-12-0. Molecular formula: C39H61NO14. Mole weight: 767.90.
Ripromycin
Ripromycin is produced by the strain of Streptomyces sp Tu 6239. It has moderate anti-gram-positive bacterial activity, but not anti-gram-negative bacteria or fungi. It inhibited the proliferation of HM02 and MCF cells with IC50 of 1.6 and 2.0 μg/mL, respectively. Molecular formula: C30H40N2O6. Mole weight: 524.65.
RIT D-2214
RIT D-2214 is a penicillin antibiotic produced by Acremonium chrysogenum. It is active against gram-positive and gram-negative bacteria. Molecular formula: C13H19N3O6S2. Mole weight: 377.4.
RK-1009
RK-1009 is an antibiotic produced by Streptomyces sp. RK-1009. Synonyms: RK 1009; RK1009. Molecular formula: C45H64N2O10. Mole weight: 793.
RK-286C
RK-286C is a protein kinase C (PKC) inhibitor produced by Streptomyces sp. RK-286. It inhibits PKC activity with IC50 of 3.0 μmol/L, as well as suppresses platelet aggregation induced by collagen and ADP. Synonyms: RK 286C; RK286C. CAS No. 126572-73-4. Molecular formula: C27H23N3O4. Mole weight: 453.5.
RK-397
RK-397 is a macrolide antibiotic produced by Streptomyces sp. 87-397. It is cytotoxic against human leukemia HL-60 and K-562 cells at a concentration of 50 μg/mL. It induces bleb-formation on K-562 cells at the concentrations over 0.05 μg/mL. Synonyms: RK 397; RK397; 14-demethyl-mycoticin; 14-demethylmycoticina. CAS No. 154396-73-3. Molecular formula: C35H56O10. Mole weight: 636.8.
RK-682 calcium salt
It is a dimeric calcium complex of the major analogue of tetronic acid complex isolated from streptomyces. It inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. Synonyms: TAN 1364B; CI 010; Calcium bis[(R)-2-oxo-3-hexadecanoyl-5-(hydroxymethyl)-2,5-dihydrofuran-4-olate]; (5R)-4-hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone, calcium salt (2:1); RK-682 calcium salt (2:1). Grades: >95% by HPLC. CAS No. 332131-32-5. Molecular formula: C42H70CaO10. Mole weight: 775.09.
RNAIII-inhibiting peptide
RNAIII-inhibiting peptide, a potent staphylococcus aureus inhibitor, is effective against cellulitis, keratitis, septic arthritis, osteomyelitis and mastitis, among other diseases. Synonyms: H-Tyr-Ser-Pro-Trp-Thr-Asn-Phe-NH2; L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparagyl-L-phenylalaninamide; L-Phenylalaninamide, L-tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-; L-Tyrosyl-L-seryl-L-prolyl-L-tryptophyl-L-threonyl-L-asparaginyl-L-phenylalaninamide; RNAIII-inhibiting peptide (synthetic). Grades: ≥95%. CAS No. 661485-29-6. Molecular formula: C45H56N10O11. Mole weight: 912.99.
Ro 09-1679
Ro 09-1679 is a thrombin inhibitor produced by Mortierella alpina NR6773. It inhibits thrombin, Factor Xa, trypsin and papain with IC50 values of 33.6, 3.3, 0.04 and 0.0346 μmol/L. Synonyms: L-Leucinamide, N2-(3-carboxy-1-oxo-2-propenyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (S-(E))-. CAS No. 141426-89-3. Molecular formula: C22H39N9O6. Mole weight: 525.61.
Ro 27-3225
Ro 27-3225 is a potent and selective melanocortin 4 receptor (MC4R) agonist. CAS No. 274682-89-2. Molecular formula: C39H52N12O6. Mole weight: 784.90.
Rodaplutin
Rodaplutin is a peptidylnucleoside antibiotic produced by Streptomyces sp. Sch 36605. It exhibits anti-inflammatory and moderate antibacterial activity. Synonyms: Sch-36605; Sch 36605. CAS No. 108351-49-1. Molecular formula: C24H39N9O7. Mole weight: 565.6.