BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| ACT-281959 | This molecular is a prodrug of ACT-246475 which is a selective P2Y12 receptor antagonist with a wider therapeutic window in the rat model. ACT-281959 is the phosphate of ACT-246475 and showed antithrombotic efficacy after oral administration in the rat ferric chloride model. In May 2016, Phase-I development is ongoing in France. Uses: Cardiovascular disorders;antithrombotic. Synonyms: ACT-281959; ACT 281959; ACT281959. butyl 4-((R)-3-(bis(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)-2-(6-((S)-3-methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxamido)propanoyl)piperazine-1-carboxylate. Grade: 98%. CAS No. 1159501-31-1. Molecular formula: C38H55N6O14P. Mole weight: 850.86. |  |
| ACT 335827 | ACT 335827 has been found to be an orexin OX1 receptor antagonist and could probably exhibit anxiolytic effects in vivo. Synonyms: ACT-335827; ACT 335827; ACT335827; (aR,1S)-1-[(3,4-Dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxy-N-(1-methylethyl)-a-phenyl-2(1H)-isoquinolineacetamide. Grade: ≥98% by HPLC. CAS No. 1354039-86-3. Molecular formula: C31H38N2O5. Mole weight: 518.64. | |
| ACT-389949 | ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX) with EC50 of 3 nM for FPR2/ALX internalization into monocytes. ACT-389949 exhibits anti-inflammatory activity. CAS No. 1258417-54-7. Molecular formula: C20H18F2N6O3. Mole weight: 428.4. | |
| ACT-451840 | ACT-451840 is a drug that exhibits antimalarial activity. It has potent activity against sensitive and resistant Plasmodium falciparum strains. Synonyms: ACT451840; ACT 451840. Grade: 97%. CAS No. 1984890-99-4. Molecular formula: C47H54N6O3. Mole weight: 750.99. | |
| ACT 462206 | ACT 462206 has been found to be a potent and selective dual orexin receptor antagonist and could exhibit anxiolytic-like activities. Synonyms: ACT-462206; ACT 462206; ACT462206; (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide. Grade: ≥99% by HPLC. CAS No. 1361321-96-1. Molecular formula: C20H24N2O4S. Mole weight: 388.48. | |
| ACTB-1003 | ACTB-1003 is an oral kinase inhibitor with multiple modes of action, targeting cancer mutations via FGFR inhibition FGFR1, angiogenesis through inhibition of VEGFR2, Tie-2, and induces apoptosis likely by targeting RSK and p70S6K. It is highly active with dose-dependent tumor growth inhibition in cell lines with FGFR genetic alterations - OPM2 human multiple myeloma and the murine leukemia Ba/F3-TEL-FGFR1. Synonyms: ACTB1003; ACTB 1003; ACTB-1003. Grade: >98%. CAS No. 939805-30-8. Molecular formula: C27H26F5N7O3. Mole weight: 591.53. | |
| ACTH 11-24 acetate | ACTH(11-24) is a fragment of the adrenocorticotropic hormone (ACTH) and an antagonist of the adrenocorticotropic hormone (ACTH) receptor that induces cortisol release. Synonyms: ACTH (11-24) acetate; Adrenocorticotropic Hormone (11-24) acetate. Molecular formula: C79H138N24O18. Mole weight: 1712.09. | |
| ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: SYSMEHFRWGKPV-OH. Grade: ≥98%. Molecular formula: C75H106N20O19S·xCF3COOH. Mole weight: 1623.83. | |
| ACTH (1-17) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (1-17) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (1-17); SYSMEHFRWGKPVGKKR-OH; Cortrophin; Corticotrophin. Grade: ≥98%. Molecular formula: C95H145N29O23S·xCF3COOH. Mole weight: 2093.42. | |
| ACTH (4-10) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | Adrenocorticotropic hormone (ACTH) (4-10) is an endogenous peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: Adrenocorticotropic hormone (4-10); Corticotropin (4-10); H-Met-Glu-His-Phe-Arg-Trp-Gly-OH. Grade: ≥95%. Molecular formula: C44H59N13O10S·xCF3COOH. Mole weight: 962.09. | |
| ACTH (4-10) Trifluoroacetate | ACTH (4-10) is a fragment of Adrenocorticotropic Hormone (ACTH), a melanocortin 4 (MC4R) receptor agonist. Synonyms: Adrenocorticotropic Hormone (ACTH) (4-10) TFA. Molecular formula: C46H60F3N13O12S. Mole weight: 1076.12. | |
| ACTH (6-24) (human, mouse, rat, porcine, bovine, ovine) trifluoroacetate salt | ACTH (6-24) is a peptide fragment of adrenocorticotropic hormone, a peptide hormone found in the brain that is involved in the biological stress response. Synonyms: HFRWGKPVGKKRRPVKVYP; Corticotropin-(6-24)-peptide. Grade: ≥95%. CAS No. 33512-65-1. Molecular formula: C111H175N35O21·xCF3COOH. Mole weight: 2335.8. | |
| Activated Protein C (390-404), human acetate | Activated Protein C (390-404) human, a peptide of the activated protein C (a vitamin K-dependent serine protease), effectively inhibits the anticoagulant activity of APC. Molecular formula: C93H134N22O25. Mole weight: 1960.19. | |
| Actoxumab | Actoxumab is a human monoclonal antibody that binds to C. difficile toxin A and thus preventing toxin from binding to host cells. Actoxumab was developed in conjunction with bezlotoxumab for the treatment of Clostridioides difficile infection. Synonyms: MK-3415; MK 3415; MK3415; GS-CDA1; CDA1. Grade: 95%. CAS No. 1245634-25-6. Molecular formula: C6476H10000N1740O2010S45. Mole weight: 145.8 kDa. | |
| Aculene D | Aculene D is a fungal metabolite and it shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026. Aculene D could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations. CAS No. 2043948-38-3. Molecular formula: C14H20O2. Mole weight: 220.31. | |
| Acumapimod | Acumapimod is a P38 mitogen-activated protein kinase inhibitor with IC50 value of less than 1 μM for p38α. Phase II clinical trials for the treatment of Chronic obstructive pulmonary disease are on-going. Uses: Chronic obstructive pulmonary disease. Synonyms: BCT-197; BCT197; BCT 197; BCT197A2201; Acumapimod; 3-(5-amino-4-(3-cyanobenzoyl)-1H-pyrazol-1-yl)-N-cyclopropyl-4-methylbenzamide. Grade: 98%. CAS No. 836683-15-9. Molecular formula: C22H19N5O2. Mole weight: 385.42. | |
| ACY-738 | ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. Synonyms: ACY-738; ACY 738; ACY738. Grade: 98%. CAS No. 1375465-91-0. Molecular formula: C14H14N4O2. Mole weight: 270.29. | |
| ACY-775 | ACY-775 is a selective Histone Deacetylase 6 (HDAC6) inhbiitor with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs. ACY-775 has the antidepressant-like properties of other HDAC inhibitors. Uses: Antidepressant. Synonyms: ACY-775; ACY 775; ACY775; 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide. Grade: 95%. CAS No. 1375466-18-4. Molecular formula: C17H19FN4O2. Mole weight: 330.36. | |
| ACY-957 | ACY-957 is a selective and orally active HDAC1 and HDAC2 inhibitor, with IC50s of 7 nM, 18 nM and 1300 nM against HDAC1/2/3, respectively. It has no inhibition on HDAC4/5/6/7/8/9. It can be used to treat diseases such as cancer, HIV and sickle cell anemia. Synonyms: N-[2-Amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-6-quinolinecarboxamide; 6-Quinolinecarboxamide, N-[2-amino-5-(2-thienyl)phenyl]-2-(1-piperazinyl)-. Grade: ≥95%. CAS No. 1609389-52-7. Molecular formula: C24H23N5OS. Mole weight: 429.54. | |
| AcycloATP | AcycloATP is a modified deoxyoligonucleotide (dNTP) that can release pyrophosphate to produce fluorescence. CAS No. 72710-15-7. Molecular formula: C8H14N5O11P3. Mole weight: 449.15. | |
| AcycloBromoUTP | AcycloBromoUTP is a modified deoxyoligonucleotide that can release pyrophosphate to produce fluorescence. Synonyms: Acyclobromouridine-Triphosphate; Acyclic Bromo-UTP. Molecular formula: C7H12BrN2O13P3. Mole weight: 505.0. | |
| AcycloCTP | AcycloCTP is a modified deoxyoligonucleotide that can release pyrophosphate to produce fluorescence. Synonyms: Triphosphoric acid, P-[2-[(4-amino-2-oxo-1(2H)-pyrimidinyl)methoxy]ethyl] ester. CAS No. 72710-16-8. Molecular formula: C7H14N3O12P3. Mole weight: 425.12. | |
| a-Cyclodextrin octadecaacetate | a-Cyclodextrin octadecaacetate is an alpha-cyclodextrin derivative, exhibiting profound delivery potential. By virtue of its exceptional architecture, it engenders a marked augmentation in compound stability and solubility, thereby emerging as an optimal excipient in diverse pharmaceutical formulations. Synonyms: Hexakis (2,3,6-tri-O-acetyl)-a-cyclodextrin; a-Cyclodextrin, octadecaacetate; HAcACD; Peracetylated-αCD. CAS No. 23661-37-2. Molecular formula: C72H96O48. Mole weight: 1729.50. | |
| Acyclovir-5'-monophosphate | Acyclovir-5'-monophosphate is a nucleotide analog that has the potential to treat herpes virus infections. Uses: Antiviral agents. Synonyms: 2-Amino-1,9-dihydro-9-[[2-(phosphonooxy)ethoxy]methyl]-6H-purin-6-one; Acycloguanosine Monophosphate. Grade: ≥ 95% by HPLC. CAS No. 66341-16-0. Molecular formula: C8H12N5O6P (free acid). Mole weight: 305.18 (free acid). | |
| Acyclovir-5'-triphosphate | Acyclovir-5'-triphosphate is a derivative of Acyclovir, an agent resistant to herpesvirus DNA polymerase. Uses: Acyclovir-5'-triphosphate is a derivative of acyclovir. Synonyms: Acyclovir triphosphate; AcycloGTP; Acycloguanosine triphosphate; Aciclovir-triphosphate; 9-(2-Hydroxyethoxymethyl)guanine triphosphate; Aciclvir-triphosphate; Triphosphoric acid, P-(2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)ethyl) ester. Grade: 95% 100mM Sodium Solution. CAS No. 66341-18-2. Molecular formula: C8H14N5O12P3. Mole weight: 465.14. | |
| Acyclovir 7,9'-Diguanyl analog | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: 2-Amino-9-({2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethoxy}methyl)-1,7-dihydro-6H-purin-6-one. Molecular formula: C14H18N10O4. Mole weight: 390.36. | |
| Acyclovir 9,9'-Diguanyl analog | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: 1,2-Bis[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethane; O-((Guanin-9-yl)methyl) acyclovir; O-[(Guanin-9-yl)methyl] Acyclovir. CAS No. 166762-90-9. Molecular formula: C14H16N10O4. Mole weight: 388.34. | |
| Acyclovir L-Isoleucinate | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl L-isoleucinate. Grade: > 95%. CAS No. 142963-63-1. Molecular formula: C14H22N6O4. Mole weight: 338.37. | |
| Acyclovir Related Compound A | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: Acyclovir Acetate; 9-[[2-(Acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro-6H-purin-6-one; 9-(2-Acetoxyethoxymethyl)guanine; USP Acyclovir Related Compound A. Grade: > 95%. CAS No. 102728-64-3. Molecular formula: C10H13N5O4. Mole weight: 267.25. | |
| Acyclovir Related Compound F | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: N2-Acetyl Acyclovir. Grade: > 95%. CAS No. 110104-37-5. Molecular formula: C10H13N5O4. Mole weight: 267.25. | |
| Acyclovir triphosphate (triethylammonium salt form) | An impurity of Acyclovir. Acyclovir is an antiviral drug used for the treatment of infections caused by herpes simplex virus and herpes zoster virus. It acts via inhibiting the production of virus' DNA. Synonyms: 9-(2-Hydroxyethoxymethyl)guanine triphosphate triethylammonium; ACGTP (triethylammonium salt form). Grade: 90%. CAS No. 186367-53-3. Molecular formula: C8H14N5O12P3.C6H15N. Mole weight: 465.147 (free acid). | |
| Acyline | Acyline is a novel GnRH antagonist found in animal studies to be a potent suppressor of circulating gonadotropin and testosterone (T) levels. Synonyms: MER-104; MER104; MER 104. CAS No. 170157-13-8. Molecular formula: C80H102ClN15O14. Mole weight: 1533.23. | |
| AD 01 | FKBPL (FK506-binding protein like)-based peptide. Binds to and upregulates expression of CD44. Inhibits breast cancer stem cell (BCSC) growth. Decreases pluripotency markers and promotes differentiation of BCSCs. Also inhibits endothelial cell migration as well as tubule and microvessel formation in vitro and in vivo. Blocks tumor growth in xenograft models. Synonyms: AD 01; 959961-23-0; EX-A7468; H-Gln-Ile-Arg-Gln-Gln-Pro-Arg-Asp-Pro-Pro-Thr-Glu-Thr-Leu-Glu-Leu-Glu-Val-Ser-Pro-Asp-Pro-Ala-Ser-OH. Grade: ≥95%. CAS No. 959961-23-0. Molecular formula: C115H187N33O42. Mole weight: 2703.94. | |
| a-D-1,5-Difluoroglucose | a-D-1,5-Difluoroglucose is an exquisite and indispensable biomedical compound aptly tailored for its pivotal role in the realm of positron emission tomography (PET) imaging. It acts as a scintillating radiotracer emulating the very essence of glucose. Synonyms: 5-C-Fluoro-a-D-glucopyranosyl fluoride. CAS No. 173349-22-9. Molecular formula: C6H10F2O5. Mole weight: 200.14. | |
| AD 198 | AD 198 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: N-Benzyladriamycin-14-Valerate; 2-[(2S,4S)-4-{[3-(Benzylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy}-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-2-tetracenyl]-2-oxoethyl valerate; Pentanoic acid, 2-(1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-4-((2,3,6-trideoxy-3-((phenylmethyl)amino)-α-L-lyxo-hexopyranoxyl)oxy)-2-naphthacenyl)-2-oxoethyl ester, (2S-cis)-. CAS No. 98983-21-2. Molecular formula: C39H43NO12. Mole weight: 717.76. | |
| AD57 | AD57 is a multikinase inhibitor that inhibits RET, BRAF, S6K and Src. It is used in cancer therapeutic. Synonyms: 1-(4-(4-Amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea. Grade: >98.0%. CAS No. 1093380-42-7. Molecular formula: C22H20F3N7O. Mole weight: 455.45. | |
| AD57 hydrochloride | AD57 is a polypharmacological cancer therapeutic, in that it is designed to modulate multiple targets related to cancer. Grade: ≥98%. Molecular formula: C22H20F3N7O·HCl. Mole weight: 491.9. | |
| A,D-6-di-acetyl-beta-Cyclodextrin | A,D-6-di-acetyl-beta-Cyclodextrin is a pharmaceutical excipient extensively used in the biomedical industry for its ability to enhance drug solubility and stability. It is commonly employed in the formulation of various drugs, including nonsteroidal anti-inflammatory drugs (NSAIDs), antifungals and anticancer drugs. Grade: 97%. Molecular formula: C46H74O37. Mole weight: 1219.06. | |
| AD80 | AD80, also called as A-196, is a multikinase inhibitor that inhibits against human BRAF, S6K, and SRC and shows strong activity against RET inhibitor. Synonyms: 1-[4-(4-amino-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-3-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea; AD80; AD-80; AD 80; s8518. CAS No. 1384071-99-1. Molecular formula: C22H19F4N7O. Mole weight: 473.43. | |
| Adalimumab | Adalimumab is a monoclonal antibody that targets tumor necrosis factor-alpha (TNFα). Adalimumab has been used to treat inflammatory conditions including rheumatoid arthritis, Crohn's disease, and ankylosing spondylitis. CAS No. 331731-18-1. Molecular formula: C6428H9912N1694O1987S46. Mole weight: 144 kDa. | |
| Adamantane | Adamantane is a colorless, crystalline chemical compound with a camphor-like odor. With a formula C10H16, it is a cycloalkane and also the simplest diamondoid. Adamantane molecules consist of four connected cyclohexane rings arranged in the "armchair" configuration. It is unique in that it is both rigid and virtually stress-free. A boat-shaped configuration can also exist. Adamantane is the most stable among all the isomers with formula C10H16, which include the somewhat similar twistane. The spatial arrangement of carbon atoms in adamantane molecule is the same as in the diamond crystal. This motivates the name adamantane, which is derived from the Greek adamantinos (relating to steel or diamond).The discovery of adamantane in petroleum in 1933 launched a new field of chemistry dedicated to studying the synthesis and properties of polyhedral organic compounds. Adamantane derivatives have found practical application as drugs, polymeric materials and thermally stable lubricants. Uses: Building blocks. Synonyms: adamantane. Grade: > 98 %. CAS No. 281-23-2. Molecular formula: C10H16. Mole weight: 136.23. | |
| Adamantane-1,3,5,7-tetraol | Adamantane-1,3,5,7-tetraol is an impurity of Vildagliptin. It is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Synonyms: Vildagliptin Impurity 28. Grade: ≥95%. CAS No. 16104-28-2. Molecular formula: C10H16O4. Mole weight: 200.23. | |
| Adamantane-2 (1-Nitro-3,5-Dimethyladamantane) | An analogue of Adamantane. Synonyms: 3,5-Dimethyl-1-nitroadamantane. Grade: > 95%. CAS No. 6588-68-7. Molecular formula: C12H19NO2. Mole weight: 209.29. | |
| Adamantanine | Adamantanine, a γ-turn inducer, is a potential cholecystikinin-B (CCK-B) receptor selective ligand that inhibits the transport of L-leucine and L-methionine into Ehrlich ascites cells. Synonyms: Tricyclo[3.3.1.13,7]decane-2-carboxylic acid, 2-amino-; 2-Aminotricyclo[3.3.1.13,7]decane-2-carboxylic acid; NSC 145160. Grade: 95%. CAS No. 42381-05-5. Molecular formula: C11H17NO2. Mole weight: 195.26. | |
| ADAMTS-5 inhibitor | ADAMTS-5 (A Disintegrin And Metalloproteinase with ThromboSpondin motifs 5) is an aggrecanase-2. ADAMTS-5 is involved in the catabolism of aggrecan and collagen in the articular cartilage matrix during Osteoarthritis (OA). Synonyms: ADAMTS-5 Inhibitor; ADAMTS 5 Inhibitor; ADAMTS5 Inhibitor; 5-[[5-[(4-chlorophenyl)methylsulfanyl]-1-methyl-3-(trifluoromethyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one. Grade: 99%. CAS No. 929634-33-3. Molecular formula: C16H11ClF3N3OS3. Mole weight: 449.92. | |
| Adapalene | Adapalene is more active than indomethacin, betamethasone valerate, tretinoin, isotretinoin or etretinate in inhibiting lipoxygease activity, but it has little activity against cyclo-oxygenase. Synonyms: ADAPALENE; Differin; Adaferin; Adapaleno; Adapalenum; CD-271; CD271; CD 271. Grade: >98%. CAS No. 106685-40-9. Molecular formula: C28H28O3. Mole weight: 412.52. | |
| Adapalene-13C6 | Labelled Adapalene. Adapalene is a topical retinoid commonly used to treat acne. Synonyms: 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid 13C6. Grade: > 95%. Molecular formula: C22[13C]6H28O3. Mole weight: 418.47. | |
| Adapalene-1',4'-dione | Adapalene-1',4'-dione is an impurity of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid; 6-(3-((3r,5r,7r)-Adamantan-1-yl)-4-methoxyphenyl)-1,4-dioxo-1,4-dihydronaphthalene-2-carboxylic Acid. Molecular formula: C28H26O5. Mole weight: 442.50. | |
| Adapalene-d15 | Labelled Adapalene. Adapalene is a topical retinoid commonly used to treat acne. Synonyms: 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid D15. Grade: > 95%. Molecular formula: C28H13O3D15. Mole weight: 427.62. | |
| Adapalene Dimer Impurity | Adapalene Dimer Impurity is an impurity of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: Di-6-(4-methoxyphenyl)-2-naphthoic Acid Adamantane; 6,6'-[Tricyclo[3.3.1.13,7]decane-1,2-diylbis(4-methoxy-3,1-phenylene)]di(2-naphthoic acid); 2-Naphthalenecarboxylic acid, 6,6'-[tricyclo[3.3.1.13,7]decane-1,2-diylbis(4-methoxy-3,1-phenylene)]bis-; 6,6'-(adamantane-1,2-diylbis(4-methoxy-3,1-phenylene))bis(2-naphthoic acid). Molecular formula: C46H40O6. Mole weight: 688.80. | |
| Adapalene EP Impurity A | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: [2,2'-Binaphthalene]-6,6'-dicarboxylic Acid; 2,2'-Binaphthalene-6,6'-dicarboxylic Acid; Adapalene Related Compound E. CAS No. 932033-58-4. Molecular formula: C22H14O4. Mole weight: 342.34. | |
| Adapalene EP Impurity B | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: Hydroxy Adapalene; Hydroxyadapalene; 6-(3-(3-Hydroxytricyclo(3.3.1.13,7)dec-1-yl)-4-methoxyphenyl)naphthalene-2-carboxylic acid. Grade: >95%. CAS No. 1346599-76-5. Molecular formula: C28H28O4. Mole weight: 428.53. | |
| Adapalene EP Impurity C | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: 1-(2-Methoxyphenyl)ticyclo[3.3.1.13,7]decane; 1-(o-Methoxyphenyl)adamantane; o-Adamantylanisole; Adapalene Related Compound C. CAS No. 43109-77-9. Molecular formula: C17H22O. Mole weight: 242.36. | |
| Adapalene EP Impurity D | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: 1,1'-(4,4'-Dimethoxy[1,1'-biphenyl]-3,3'-diyl)bistricyclo[3.3.1.13,7]decane; 2,2'-Bis-(1-adamantyl)-4,4'-dimethoxybiphenyl; Adapalene Related Compound D. CAS No. 932033-57-3. Molecular formula: C34H42O2. Mole weight: 482.70. | |
| Adapalene Glucuronide | Adapalene Glucuronide is a possible metabolite of Adapalene, which is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne. Synonyms: CD-271-glucuronide; (2S,3S,4S,5R,6S)-6-((6-(3-(adamantan-1-yl)-4-methoxyphenyl)-2-naphthoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid; β-D-Glucopyranuronic Acid 1-[6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylate]; Adapalene Acylglucuronide. Grade: ≥95%. CAS No. 359699-07-3. Molecular formula: C34H36O9. Mole weight: 588.64. | |
| Adapalene Related Compound A | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: Methyl 6-bromo-2-naphthoate; methyl 6-bromo-2-napthoate. Grade: 98 %. CAS No. 33626-98-1. Molecular formula: C12H9BrO2. Mole weight: 265.10. | |
| Adapalene Related Compound B | An impurity of the third-generation topical retinoid Adapalene, which is commonly used to treat skin conditions such as acne and keratosis pilaris. Synonyms: Methyl 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylate; 6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic Acid Methyl Ester; Adapalene Methyl Ester. Grade: > 95%. CAS No. 106685-41-0. Molecular formula: C29H30O3. Mole weight: 426.56. | |
| Adapalene sodium salt | Adapalene sodium salt, a synthetic retinoid, is a Retinoic acid receptor agonist (RAR). It is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. It is possibly more effective than tretinoin 0.025% gel in the treatment of acne vulgaris. Synonyms: CD 271 sodium salt; Differin sodium salt; 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid sodium salt; 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid sodium salt; Sodium 6-[3-(adamantan-1-yl)-4-methoxyphenyl]-2-naphthoate; 2-Naphthalenecarboxylic acid, 6-(4-methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-, sodium salt (1:1). Grade: >98%. CAS No. 911110-93-5. Molecular formula: C28H27NaO3. Mole weight: 434.50. | |
| Adaphostin | Adaphostin is a p210bcr/abl tyrosine kinase inhibitor with IC50 value of 14 μM. It shows anti-proliferative activity in human prostate cancer cell line PC-3, leukemia models and other cancer cell lines. It is a potent inducer of myeloid cell death. It could induce a degradation of WT and mutated Bcr/Abl and induce apoptosis in tumor cells. It shows selectivity for chronic myelogenous leukemia (CML) myeloid progenitors in vitro. It is used as a novel antitumor agent. Synonyms: 4-[[(2,5-Dihydroxyphenyl)methyl]amino]benzoic acid tricyclo[3.3.1.13,7]dec-1-yl ester; AG 957 Adamantyl Ester; NSC 680410; AG957 Adamantyl Ester; NSC680410; AG-957 Adamantyl Ester; NSC-680410. Grade: ≥98% by HPLC. CAS No. 241127-58-2. Molecular formula: C24H27NO4. Mole weight: 393.48. | |
| Adaptaquin | Adaptaquin is an inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase 2 (PHD2) with IC50 value of 2 μM in a reporter assay using SH-SY5Y-ODD-Luc cells. It displays neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models by inhibition of ATF4 dependent genes. It reduces neuronal death and behavioral deficits after intracerebral hemorrhage (ICH) in several rodent models. It blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. It stabilizes HIF-1α protein and induces expression of the HIF1-regulated genes EPO and VEGF in SH-SY5Y human neuroblastoma cells. It is used in ischemic injury research, renal anemia, and used as an antioxidant. It is also used in pyruvate dehydrogenase (PDH) related research. Synonyms: 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol. Grade: ≥97% by HPLC. CAS No. 385786-48-1. Molecular formula: C21H16ClN3O2. Mole weight: 377.82. | |
| a-D-Arabinopyranosyl azide | a-D-Arabinopyranosyl azide is a compound used in the biomedical industry for its potential role in treating cancer. It functions as an azide-based probe to label and visualize cancer cells through bioorthogonal chemistry. Synonyms: Alpha-D-arabinopyranosyl azide. CAS No. 138892-04-3. Molecular formula: C5H9N3O4. Mole weight: 175.14. | |
| Adarotene | Adarotene is an atypical retinoid and a promising anti-tumour agent with selective apoptotic activity on the leukaemic blast. The anti-tumour activity of the compound has been associated with its capacity to induce DNA double stranded breaks. Synonyms: ST1926; ST 1926; ST-1926. Grade: 0.98. CAS No. 496868-77-0. Molecular formula: C25H26O3. Mole weight: 374.47. | |
| Adavivint | Adavivint is a Wnt signaling pathway inhibitor. Adavivint was reported to induce differentiation of hMSC into functional chondrocytes, and decrease cartilage catabolic marker levels. Uses: Anti-inflammatory agents. Synonyms: Butanamide, N-[5-[3-[7-(3-fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl]-3-pyridinyl]-3-methyl-; N-[5-[3-[7-(3-Fluorophenyl)-3H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl]-3-pyridinyl]-3-methylbutanamide; Lorecivivint; SM 04690; SM-04690; SM04690. Grade: >98%. CAS No. 1467093-03-3. Molecular formula: C29H24FN7O. Mole weight: 505.55. | |
| Adecatumumab | Adecatumumab is a human IgG1 monoclonal antibody directed against the epithelial cell adhesion molecule (EpCAM). EpCAM is expressed in almost all adenocarcinomas and its activity is not dependent of K-Ras status. Adecatumumab acts as a drug candidate for the treatment of cancers. Synonyms: MT-201; MT 201; MT201. Grade: 95%. CAS No. 503605-66-1. Molecular formula: C6552H10080N1740O2052S46. Mole weight: 147.5 kDa. | |
| Adefovir Dipivoxyl Impurity A | An analogue of Adefovir. Synonyms: Adefovir Monopivoxil; Mono-POM Adefovir; Mono(pivaloyloxymethyl) Adefovir; 2,2-Dimethylpropanoic Acid [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]hydroxyphosphinyl]oxy]methyl Ester. Grade: > 95%. CAS No. 142341-05-7. Molecular formula: C14H22N5O6P. Mole weight: 387.34. | |
| Adefovir Dipivoxyl Impurity C | An impurity of Adefovir, a medication used for the treatment of infections with hepatitis B virus. Synonyms: Mono-POM Ethyl Adefovir; Mono(pivaloyloxymethyl) Ethyl Adefovir; 2,2-Dimethylpropanoic Acid [[[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]ethoxyphosphinyl]oxy]methyl ester. Grade: > 95%. CAS No. 142341-04-6. Molecular formula: C16H26N5O6P. Mole weight: 415.39. | |
| Adefovir disoproxil | Adefovir disoproxil is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: O,O-Bis(isopropoxycarbonyloxymethyl) [(6-amino-9H-purin-9-yl)ethyloxy]methylphosphonate; Desmethyl Tenofovir Disoproxil; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, bis(1-methylethyl) ester, 5-oxide; (((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy)bis(methylene) isopropyl dicarbonate; [2-(6-aminopurin-9-yl)ethoxymethyl-(isopropoxycarbonyloxymethoxy)phosphoryl]oxymethyl isopropyl carbonate; [[2-(6-Amino-9H-purine-9-yl)ethoxy]methyl]phosphonic acid bis[(isopropoxycarbonyloxy)methyl] ester. Grade: ≥95%. CAS No. 365417-53-4. Molecular formula: C18H28N5O10P. Mole weight: 505.42. | |
| Adefovir disoproxil 2-butenedioate | Adefovir disoproxil 2-butenedioate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, 2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide 2-Butenedioate; ((((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) but-2-enedioic acid; Desmethyl Tenofovir Disoproxoil 2-Butenedioate. Grade: ≥95%. CAS No. 1798422-29-3. Molecular formula: C22H32N5O14P. Mole weight: 621.49. | |
| Adefovir disoproxil fumarate | Adefovir disoproxil fumarate is an impurity of Tenofovir Disoproxil Fumarate, which is a potent reverse transcriptase inhibitor used to treat chronic hepatitis B and to prevent and treat HIV/AIDS. Synonyms: Desmethyl Tenofovir Disoproxoil Fumarate; 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[2-(6-amino-9H-purin-9-yl)ethoxy]methyl]-, 1,9-bis(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1); 5-[[2-(6-Amino-9H-purin-9-yl)ethoxy]methyl]-2,4,6,8-Tetraoxa-5-phosphanonanedioic Acid Bis(1-methylethyl) Ester 5-Oxide Fumarate; ((((2-(6-amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl bis(carbonate) fumarate. Grade: ≥95%. CAS No. 2251049-67-7. Molecular formula: C18H28N5O10P.C4H4O4. Mole weight: 621.49. | |
| AdemA-GalNAc Phosphoramidite | AdemA-GalNAc Phosphoramidite is a specialized phosphoramidite reagent used for the synthesis of oligonucleotides with liver-targeting capabilities. It combines adenine and GalNAc (N-Acetylgalactosamine) moieties to facilitate targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). This reagent enhances the efficiency of oligonucleotide uptake in liver cells. Synonyms: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[2-[2-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]ethoxy]ethoxy]methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-((5-((2-(2-((((2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl)oxy)methoxy)ethoxy)ethyl)amino)-5-oxopentyl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate; GalNAc Similar. Grade: ≥95%. CAS No. 1953147-02-8. Molecular formula: C71H90N9O20P. Mole weight: 1420.50. | |
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