BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Hydroxyquinoline b-D-glucopyranoside | 8-Hydroxyquinoline b-D-glucopyranoside is a commendable biomedical compound known for its applications in studying neurodegenerative ailments. By fortifying the cellular antioxidant defense system and impeding neuroinflammation, it showcases promising neuroprotective attributes. Synonyms: HQGlc; 8-Quinolinyl β-D-glucopyranoside; Quinoline, 8-(β-D-glucopyranosyloxy)-; 8-Hydroxyquinoline β-D-glucoside; 8-Quinolyl β-D-glucopyranoside; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(quinolin-8-yloxy)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 29266-96-4. Molecular formula: C15H17NO6. Mole weight: 307.30. |  |
| 8-Hydroxyquinoline-b-D-glucuronide | 8-Hydroxyquinoline-b-D-glucuronide - a metabolite of 8-hydroxyquinoline - boasts a diverse range of biological activities. Its usage has proven effective as a potent inhibitor for Tau protein aggregation, which is affiliated with Alzheimers disease. This molecule establishes roles in cellular signaling pathways and cancer treatment. Synonyms: Quinolyl-8beta-glucuronic acid; 8-Quinolinyl β-D-glucopyranosiduronic acid; Glucopyranosiduronic acid, 8-quinolyl, β-D-; 8-Hydroxyquinoline glucuronide; 8-Quinolinyl glucuronide; 8-Quinolyl β-D-glucosiduronic acid; NSC 87518. CAS No. 14683-61-5. Molecular formula: C15H15NO7. Mole weight: 321.28. | |
| 8-Hydroxyquinoline b-D-glucuronide sodium salt | A versatile biomedical compound, 8-Hydroxyquinoline b-D-glucuronide sodium salt emerges as a consequential therapeutic phenomenon, effectively tackling a myriad of ailments. Emanating its prowess as a potent chelating agent, it simultaneously unveils remarkable antimicrobial attributes. An indispensable ally in pharmaceutical advancements, this compound revolutionizes the combat against microbial infections, be it bacterial or fungal in origin. Synonyms: HQG; 8-Hydroxy-1-azanaphthalene-b-D-glucopyranosiduronic acid sodium salt; β-D-Glucopyranosiduronic acid, 8-quinolinyl, monosodium salt; Sodium (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(quinolin-8-yloxy)tetrahydro-2H-pyran-2-carboxylate; 8-Quinolinyl β-D-glucopyranosiduronic acid sodium salt; 8-Hydroxyquinoline glucuronide sodium salt; 8-Quinolinyl glucuronide sodium salt; 8-Quinolyl β-D-glucosiduronic acid sodium salt. CAS No. 207728-71-0. Molecular formula: C15H14NNaO7. Mole weight: 343.26. | |
| 8-Hydroxy Warfarin | One of the impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: 4,8-Dihydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one; 3-(α-Αcetonylbenzyl)-4,8-dihydroxycoumarin. CAS No. 17834-04-7. Molecular formula: C19H16O5. Mole weight: 324.34. | |
| 8-Hydroxy Warfarin-d5 | One of the labelled impurities of Warfarin, which is a kind of Coumarin anticoagulant. Synonyms: 4,8-Dihydroxy-3-[3-oxo-1-(phenyl-d5)-butyl]-2H-1-benzopyran-2-one; 3-(α-Αcetonylbenzyl)-4,8-dihydroxycoumarin-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 94820-66-3. Molecular formula: C9H11O5D5. Mole weight: 329.37. | |
| 8-Hydroxy-xyloguanosine | 8-Hydroxy-xyloguanosine is a biomedically important compound widely used in the research and development of various pharmaceutical drugs. It serves as a key intermediate for synthesizing nucleotide analogs that target viral diseases, such as hepatitis C and respiratory syncytial virus. Its unique structure makes it a crucial component for studying antiviral agents and designing potential therapeutics to combat these infectious diseases effectively. Synonyms: 2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-(hydroxy)-1H-purin-6-one. Grade: ≥95%. Molecular formula: C10H13N5O6. Mole weight: 299.24. | |
| 8-Iodoadenosine | 8-Iodoadenosine, a biomedical product, has emerged as a pivotal intervention for diverse ailments and medical circumstances. This compound exhibits exceptional prospects in oncological investigations, particularly pertaining to the innovation of avant-garde anticancer modalities. Profoundly impeding cellular mechanisms, it manifests as a strong suppressor of cancerous cell propagation whilst concurrently instigating apoptosis. Synonyms: 8-Indoo adenosine; 8-I-rA; 8-I-Adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-iodo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Adenosine, 8-iodo-. Grade: 97%. CAS No. 31281-88-6. Molecular formula: C10H12IN5O4. Mole weight: 393.14. | |
| 8-Iodo-ADP | 8-Iodo-ADP is a remarkable biomedical compound unlocking the enigmatic realm of purinergic receptors, unraveling their binding mechanics and activating potential. Synonyms: (8I-ADP); 8-Iodo-adenosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O10P2I (free acid). Mole weight: 553.10 (free acid). | |
| 8-Iodo-AppNHp | 8-Iodo-AppNHp - a renowned biochemical reagent - finds widespread usage in the G protein-coupled receptor (GPCR) study arena. Its non-hydrolyzable analog of GTP ensures sturdy receptor-G protein complexes, enabling downstream signaling pathway investigations. Apart from resolving cardiovascular illnesses and cancer investigations, it has contributed to various other GPCR studies. Synonyms: (8I-AppNHp, 8I-AMPPNP); 8-Iodo-adenosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H16N6O12P3I (free acid). Mole weight: 632.09 (free acid). | |
| 8-Iodo-ATP | 8-Iodo-ATP is a potent and specific agonist for P2X receptors, which are involved in various pathophysiological processes such as pain perception and inflammation. It is widely used in the biomedical industry to study the function and regulation of P2X receptors and to develop new drugs targeted at these receptors for the research of chronic pain, neuroinflammatory disorders and other conditions. Synonyms: (8I-ATP); 8-Iodo-adenosine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 82049-15-8. Molecular formula: C10H15N5O13P3I (free acid). Mole weight: 633.08 (free acid). | |
| 8-Iodo-GDP | 8-Iodo-GDP, a nucleotide analog, facilitates in the study of molecular mechanisms of signal transduction with promising applications in cancer therapies. Along with its ability to inhibit assembly and disassembly of the microtubule network,it has also garnered significant attention for its potential in treating neurological diseases, including Alzheimer's and Huntington's. Synonyms: (8I-GDP); 8-Iodo-guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2I (free acid). Mole weight: 569.10 (free acid). | |
| 8-Iodo-GppNHp | 8-Iodo-GppNHp, a chemical compound employed in biomedicine to inquire into G-protein signaling pathways, often functions as a non-hydrolyzable GTP analog, providing a means of exploring the activity of G-protein coupled receptors and their associated downstream effectors and target proteins. Its application has examined various afflictions, such as cancer and neurological disorders, advancing our understanding of these conditions. Synonyms: (8I-GppNHp, 8I-GMPPNP); 8-Iodo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3I (free acid). Mole weight: 648.09 (free acid). | |
| 8-Iodo-GTP | 8-Iodo-GTP, a modified nucleotide, serves as a guanine nucleotide-binding proteins (G proteins) substrate for biochemical research. Its highly selective incorporation into G proteins allows for the investigation of their interactions with enzymes and receptors. Furthermore, researchers have studied its potential efficacy in the treatment of cancer. Synonyms: (8I-GTP); 8-Iodo-guanosine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1071796-43-4. Molecular formula: C10H15N5O14P3I (free acid). Mole weight: 649.07 (free acid). | |
| 8-Iodo-guanosine | 8-Iodo-guanosine, a chemical compound used in biomedical research, has proven instrumental in studying the impacts of purine nucleoside analogs on cancers and viral infections. As an iodine-substituted guanosine derivative, it exhibits the potential to act as an inhibitor of RNA viruses like HIV and hepatitis C. Synonyms: 8-Iodoguanosine; 8-I-rG; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-iodo-1H-purin-6(9H)-one; 8-Iodocoumarin; NSC 79218. Grade: ≥97% by HPLC. CAS No. 18438-99-8. Molecular formula: C10H12IN5O5. Mole weight: 409.14. | |
| 8-iso Misoprostol | 8-iso Misoprostol is a very widely sold analog of prostaglandin E1, which is potent but acts as a non-selective agonist towards the prostanoid EP receptor subgroup. Synonyms: 9-oxo-11α,16-Dihydroxy-16-methyl-(8β)-prost-13E-en-1-oic Acid Methyl Ester. Grade: > 95%. CAS No. 1256643-55-6. Molecular formula: C22H38O5. Mole weight: 382.53. | |
| 8-Isopropyl Etodolac | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)-pyrano[3,4-b]indole-1-acetic Acid. Grade: > 95%. CAS No. 57917-63-2. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
| 8-L-Arginine-9a-glycine-vasopressin | An impurity of Vasopressin. Vasopressin is a nonapeptide hormone produced in the hypothalamus and released by the posterior pituitary gland. It is used clinically to manage central diabetes insipidus, treat hypotension in shock, and control gastrointestinal bleeding. Synonyms: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-Gly-OH(Cys1&Cys6 bridge); CYFQNCPRGG-OH(Cys1&Cys6 bridge); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-glycine (1->6)-disulfide; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-Gly-OH (Disulfide bridge: Cys1-Cys6); Endo-Gly9a-Vasopressin. Grade: ≥95%. CAS No. 114665-05-3. Molecular formula: C48H67N15O14S2. Mole weight: 1142.27. | |
| 8-MABA-cAMP | 8-MABA-cAMP is a fluorescent cAMP analogue (λexc352 nm, λem436 nm). Synonyms: 8- (4- [N- Methylanthraniloyl]aminobutylamino) adenosine- 3', 5'- monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 909782-76-9. Molecular formula: C22H28N8O7P · Na. Mole weight: 570.5. | |
| 8-MA-cAMP | 8-MA-cAMP is a selective cAMP analogue that has affinity to site B of protein kinase A type I and II. Site A activity is developed when 8-MA-cAMP acts synergistically together with other analogues. Synonyms: 8- Methylaminoadenosine- 3', 5' cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 33823-18-6. Molecular formula: C11H14N6O6P · Na. Mole weight: 380.2. | |
| 8-MBT-cAMP | 8-MBT-cAMP is a cAMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 8- (4- Mercaptobutylthio)adenosine- 3', 5' cyclic monophosphate, triethyl ammonium salt. Grade: ≥ 98% by HPLC. CAS No. 1033893-75-2. Molecular formula: C14H20N5O6PS2 (free acid). Mole weight: 449.4 (free acid). | |
| 8-Methoxy-2-aminotetraline hydrochloride | 8-Methoxy-2-Aminotetraline hydrochloride is a 5-HT1A agonist. Synonyms: 8-methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride; 2-amino-8-methoxy-1,2,3,4-tetrahydronaphthalene HCl; Aminotetraline hydrochloride, 8-Methoxy-2-; 2-amino-8-methoxy-1,2,3,4-tetrahydronaphthalene hydrochloride. Grade: 98%. CAS No. 3880-76-0. Molecular formula: C11H15NO.HCl. Mole weight: 213.7. | |
| 8-Methoxyadenosine | 8-Methoxyadenosine is a remarkable biomedical compound with antitumor and immunosuppressive properties effectively impeding RNA enhancement and viral replication. Synonyms: Adenosine, 8-methoxy-; (2R,3R,4S,5R)-2-(6-amino-8-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 3969-27-5. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| 8-Methoxycarbonyl-3-benzyl-3,4,6,6-tetra-O-acetyl-N,N-diacetyl-b-chitobioside | 8-Methoxycarbonyl-3-benzyl-3,4,6,6-tetra-O-acetyl-N,N-diacetyl-b-chitobioside is a highly potent compound with applications extending to study an array of ailments encompassing bacterial and fungal infections. Synonyms: 8-Methoxycarbonyloctyl 2-acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl)-3-O-benzyl-2-deoxy-b-D-glucopyranoside; Methyl 9-[[2-(acetylamino)-2-deoxy-3-O-(phenylmethyl)-4-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-β-D-glucopyranosyl]oxy]nonanoate; Nonanoic acid, 9-[[2-(acetylamino)-2-deoxy-3-O-(phenylmethyl)-4-O-[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]-β-D-glucopyranosyl]oxy]-, methyl ester. CAS No. 359436-87-6. Molecular formula: C39H58N2O16. Mole weight: 810.88. | |
| 8-Methoxycarbonyloctanoyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside | 8-Methoxycarbonyloctanoyl 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside, an intricate and highly potent carbohydrate intermediate, holds immense significance in the realm of biomedicine. It serves as a pivotal component for synthesizing drugs that combat glycosylation-related ailments including gaucher disease, pompe disease, Fabry disease, and cystic fibrosis. Synonyms: Octanoic acid, 8-[(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)oxy]-, methyl ester; Methyl 8-[(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)oxy]octanoate. CAS No. 93619-78-4. Molecular formula: C23H36O12. Mole weight: 504.52. | |
| 8-Methoxycarbonyloctyl 2-acetamido-2-deoxy-4-O-(a-L-fucopyranosyl)-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside | 8-Methoxycarbonyloctyl 2-acetamido-2-deoxy-4-(a-L-fucopyranosyl)-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside, an intriguing biochemical compound extensively employed in the field of biomedicine, exhibits remarkable inhibitory properties against specific enzymes crucial to the biosynthesis of select glycoproteins. With its distinctive structural composition and mechanism of action, this compound presents itself as an auspicious contender for extensive research and development within the biomedical industry. Synonyms: Nonanoic acid, 9-[[O-6-deoxy-α-L-galactopyranosyl-(1→4)-O-[β-D-galactopyranosyl-(1→3)]-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-, methyl ester; Methyl 9-[[O-6-deoxy-α-L-galactopyranosyl-(1→4)-O-[β-D-galactopyranosyl-(1→3)]-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]nonanoate; Methyl 8-{[beta-D-galactosyl-(1->3)-[alpha-L-fucosyl-(1->4)]-N-acetyl-beta-D-glucosaminyl]oxy}nonanoate; 8-Methoxycarbonyloctyl 2-acetamido-2-deoxy-4-(a-L-fucopyranosyl)-3-O-(b-D-galactopyranosyl)-b-D-glucopyranoside. CAS No. 56343-02-3. Molecular formula: C30H53NO17. Mole weight: 699.74. | |
| 8-Methoxycarbonyloctyl 2-deoxy-2-phthalimido-b-D-glucopyranoside | 8-Methoxycarbonyloctyl 2-deoxy-2-phthalimido-b-D-glucopyranoside is an exceptional biomedical compound, presenting an array of potential utilities in drug conveyance regimes, molecular visualization techniques as well as serving as an intermediary compound in the research of certain afflictions. CAS No. 106445-25-4. Molecular formula: C24H33NO9. Mole weight: 479.52. | |
| 8-Methoxycarbonyloctyl 2-deoxy-4,6-O-(4-methoxybenzylidene)-2-phthalimido-b-D-glucopyranoside | 8-Methoxycarbonyloctyl 2-deoxy-4,6-O-(4-methoxybenzylidene)-2-phthalimido-b-D-glucopyranoside is a commendable biomedical compound, exhibiting promising inhibitory nature in research of oncology and the ceaseless development of novel drugs. Synonyms: 8-Methoxycarbonyloctyl-2-deoxy-2-phthalimido-4,6-O-(methoxybenzylidene)-beta-D-glucopyranoside. CAS No. 359436-88-7. Molecular formula: C32H39NO10. Mole weight: 597.65. | |
| 8-Methoxycarbonyloctyl-3-O-benzyl-2,2-dideoxy-2,2-diphthalimido-3,4,6-tri-O-acetyl-b-cellobiose | 8-Methoxycarbonyloctyl-3-O-benzyl-2,2-dideoxy-2,2-diphthalimido-3,4,6-tri-O-acetyl-b-cellobiose is a compound prominently utilized in the biomedical domain, exhibiting potential in studying afflictions stemming from resilient compound-resistant variants. The intricacy of its distinct configuration renders it proficient in selectively targeting and suppressing the proliferation of pernicious pathogens. Synonyms: 8-Methoxycarbonyloctyl 4-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-2-deoxy-3-O-benzyl-2-phthalimido-b-D-glucopyranoside; Methyl 9-[[2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-3-O-(phenylmethyl)-4-O-[3,4,6-tri-O-acetyl-2-deoxy-2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-β-D-glucopyranosyl]-β-D-glucopyranosyl]oxy]nonanoate. CAS No. 106445-30-1. Molecular formula: C51H58N2O18. Mole weight: 987.01. | |
| 8-Methoxycarbonyloctyl-3-O-benzyl-3',4',6',6-tetra-O-acetyl-N,N'-diacetyl-β-chitobioside | A synthetic antigen which may be linked to proteins. Synonyms: 8-Methoxycarbonyloctyl-2-deoxy-2-acetamido-3-O-benzyl-4-O-(3',4',6'-tri-O-acetyl-2'-deoxy-2'acetamido-β-D-glucopyranosyl)-6-O-acetyl-β-D-glucopyranoside; 8-Methoxycarbonyloctyl-2-deoxy-2-acetamido-3-O-benzyl-4-O-(3',4',6'-tri-O-acetyl-2'-deoxy-2'acetamido-β-D-glucopyranosyl)-β-D-glucopyranoside; (2R,3S,4R,5R,6S)-5-Acetamido-6-(((2R,3S,4R,5R,6R)-5-acetamido-2-(acetoxymethyl)-4-(benzyloxy)-6-((9-methoxy-9-oxononyl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-2-(acetoxymethyl)tetrahydro-2H-pyran-3,4-diyl diacetate. Molecular formula: C41H60N2O17. Mole weight: 852.92. | |
| 8-Methoxycarbonyloctyl-4-O-(2'-acetamido-2'-deoxy-β-D-glucopyranosyl)-6-O-α-L-fucopyranosyl-2-deoxy-β-D-glucopyranoside | A synthetic antigen which may be linked to proteins. Synonyms: 8-Methoxycarbonyloctyl-4-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-6-O-a-L-fucopyranosyl-2-deoxy-b-D-glucopyranoside; 8-Methoxycarbonyloctyl-6-O-α-L-fucopyranosyl-N,N'-diacetyl-chitobioside. Grade: 95%. Molecular formula: C30H53NO17. Mole weight: 699.74. | |
| 8-Methoxycarbonyloctyl-6-O-(a-L-fucopyranosyl)-N,N-diacetyl-chitobioside | 8-Methoxycarbonyloctyl-6-O-(a-L-fucopyranosyl)-N,N-diacetyl-chitobioside is an intricate biomedical compound, rendering it a splendid candidate against cancerous malignancies and inflammatory afflictions. Synonyms: 8-Methoxycarbonyloctyl 2-acetamido-4-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-6-O-(a-L-fucopyranosyl)-b-D-glucopyranoside; Nonanoic acid, 9-[[O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-[6-deoxy-α-L-galactopyranosyl-(1→6)]-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl]oxy]-, methyl ester. CAS No. 106445-35-6. Molecular formula: C32H56N2O17. Mole weight: 740.79. | |
| 8-Methoxy Entecavir | An impurity of Entecavir. Entecavir is a reverse transcriptase inhibitor. It prevents the hepatitis B virus from multiplying and reduces the amount of virus in the body. Synonyms: 2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-8-methoxy-1H-purin-6(9H)-one; Entecavir EP impurity E. Grade: > 95%. CAS No. 2349444-69-3. Molecular formula: C13H17N5O4. Mole weight: 307.31. | |
| 8-Methyaminoadenosine | 8-Methyaminoadenosine is a potent purinergic receptor agonist that is used in the biomedical industry for the treatment of various neurological disorders including Parkinson's disease and epilepsy. It acts as a neurotransmitter and modulates the release of dopamine, reducing motor symptoms associated with Parkinson's disease. Synonyms: 9H-Purine, 6-amino-8-(methylamino)-9-β-D-ribofuranosyl-; Adenosine, 8-(methylamino)-; (2R,3R,4S,5R)-2-(6-amino-8-(methylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-(methylamino)adenosine. Grade: ≥95%. CAS No. 13389-13-4. Molecular formula: C11H16N6O4. Mole weight: 296.28. | |
| 8-Methyl-2'-deoxyadenosine | 8-Methyl-2'-deoxyadenosine is an intricately engineered derivative of adenosine, unveiling prodigious potential in obstructing the unrelenting growth of neoplastic cells, thereby holding promise in research of specific cancers. Synonyms: Adenosine, 2'-deoxy-8-methyl-; 2'-deoxy-8-methyladenosine; (2R,3S,5R)-5-(6-Amino-8-methyl-purin-9-yl)-2-hydroxymethyl-tetrahydro-furan-3-ol. Grade: ≥95%. CAS No. 85562-60-3. Molecular formula: C11H15N5O3. Mole weight: 265.27. | |
| 8-Methyl-2'-deoxyguanosine | 8-Methyl-2'-deoxyguanosine is an invaluable compound assuming a pivotal function in the amalgamation of curative substances catering to the research of viral ailments such as hepatitis C and HIV. Synonyms: Guanosine, 2'-deoxy-8-methyl-; 2'-Deoxy-8-methylguanosine; 2-Amino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-methyl-1H-purin-6(9H)-one. Grade: ≥95%. CAS No. 85819-69-8. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| 8-Methyladenosine | 8-Methyladenosine, a nucleoside present in diverse organisms' RNAs, holds significance in multiple biological processes, such as gene expression, mRNA stability, and translation regulation. Studies indicate that 8-Methyladenosine's aberrant expression associates with numerous ailments like viral infection, neurodegenerative disorders, and cancer, expediting the development of newer therapies. Synonyms: 8-Methyl Ado; 8-Methyl adenosine; Adenosine, 8-methyl-; (2R,3R,4S,5R)-2-(6-Amino-8-methyl-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 56973-12-7. Molecular formula: C11H15N5O4. Mole weight: 281.27. | |
| 8-Methylguanosine | 8-Methylguanosine is a crucial compound in biomedicine used for research purposes. It serves as a building block in the synthesis of nucleic acids and is commonly used in studies investigating RNA metabolism and epitranscriptomics. Synonyms: monomethylguanosine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-methyl-1H-purin-6(9H)-one. Grade: ≥95%. CAS No. 36799-17-4. Molecular formula: C11H15N5O5. Mole weight: 297.27. | |
| 8-Methylthioadenosine | 8-Methylthioadenosine, an extensively researched biochemical compound, is widely employed in biomedical studies due to its involvement in diverse physiological processes. With its potential therapeutic implications in cancer, liver diseases, and immunological disorders, this nucleoside serves as a valuable asset for exploring innovative treatment strategies within the realm of biomedicine. Synonyms: 8-Methylthio-adenosine; 8-methylsulphanyladenosine; 8-MeS-adenosine; Adenosine, 8-(methylthio)-; (2R,3R,4S,5R)-2-(6-amino-8-(methylthio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 29836-01-9. Molecular formula: C11H15N5O4S. Mole weight: 313.33. | |
| 8-Methylthioguanosine | 8-Methylthioguanosine is a synthetic nucleoside analogue impeding viral polymerases, widely applied in the research of viral maladies encompassing hepatitis C and influenza. Synonyms: 8-Methylthio-guanosine; 8-methylsulfanyl-guanosine; 8-Methylmercapto-guanosine; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-(methylthio)-1H-purin-6(9H)-one; 8-(Methylthio)guanosine. Grade: ≥95%. CAS No. 2104-66-7. Molecular formula: C11H15N5O5S. Mole weight: 329.33. | |
| 8-Morpholinyl-GTP | 8-Morpholinyl-GTP, a biochemical known for its role in G protein signaling, has gained popularity in scientific research to examine the etiology of several ailments. Studies exploring Parkinson's, Huntington's, and Alzheimer's diseases and cancer have utilized this compound due to its unique composition and performance. Researchers find its presence instrumental in determining molecular mechanisms of these diseases and uncovering effective treatment options. Synonyms: 8-Morpholinyl-guanosine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C14H23N6O15P3 (free acid). Mole weight: 608.28 (free acid). | |
| 8-M-PDOT | 8-M-PDOT is a melatonin receptor agonist, with 20-fold selective for the MT2 (vs MT1) subtype (pKi = 8.23 and 8.95 at human recombinant MT1 and MT2 receptors respectively). Synonyms: 8-Methoxy-2-propionamidotetralin. Grade: ≥99% by HPLC. CAS No. 134865-70-6. Molecular formula: C14H19NO2. Mole weight: 233.31. | |
| 8-[N-(2-Diphenylmethoxyethyl)-N,N-dimethylaminium]-1,3-dimethylxanthine inner salt | An impurity of Dimenhydrinate. Dimenhydrinate is an antihistamine and anticholinergic medication primarily used to prevent and treat symptoms of motion sickness, such as nausea, vomiting, and dizziness. Synonyms: 1H-Purin-8-aminium, N-[2-(diphenylmethoxy)ethyl]-2,3,6,7-tetrahydro-N,N,1,3-tetramethyl-2,6-dioxo-, inner salt; N-[2-(Diphenylmethoxy)ethyl]-2,3,6,7-tetrahydro-N,N,1,3-tetramethyl-2,6-dioxo-1H-purin-8-aminium inner salt; Dimenhydrinate Impurity 1; 8-((2-(Benzhydryloxy)ethyl)dimethylammonio)-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide. Grade: ≥95%. CAS No. 64487-94-1. Molecular formula: C24H27N5O3. Mole weight: 433.51. | |
| 8-N3-6-[DY-547]-AE-cAMP | 8-N3-6-[DY-547]-AE-cAMP is a photosensitive analogue for photoaffinity labelling. It can be immobilized by irradiation of UV light. Synonyms: 8-Azido-N6-(2-[DY-547]-aminoethyl)adenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C42H48N11Na2O13PS2. Mole weight: 1056. | |
| 8-N3-cAMP | 8-N3-cAMP is an analogue of cAMP binding proteins used for photoaffinity labelling. Uses: Affinity labels. Synonyms: 8- Azidoadenosine- 3', 5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 31966-52-6. Molecular formula: C10H10N8O6P · Na. Mole weight: 392.2. | |
| 8-N3-ε-ADP | 8-N3-ε-ADP is a 8-N3-ADP analogue with photosensitive activity and a ε-ADP analogue with fluorescent property, which is used for photoaffinity labelling of ADP binding proteins and subsequent detection of the fluorescent label (λexc285 nm, λem410 nm). Synonyms: 8- Azido- 1, N6- ethenoadenosine- 5'- O- diphosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C12H15N8O10P2 (free acid). Mole weight: 493.3 (free acid). | |
| 8-N3-ε-ATP | 8-N3-ε-ATP is a photosensitive analogue of 8-N3-ATP as well as a fluorescent analogue of ε-ATP, which can be used for photoaffinity labelling of ATP binding proteins and subsequent detection of the fluorescent label (λexc285 nm, λem412 nm). Synonyms: 8- Azido- 1, N6- ethenoadenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 66895-05-4. Molecular formula: C12H15N8O13P3 (free acid). Mole weight: 572.2 (free acid). | |
| 8-N3-ε-cAMP | 8-N3-ε-cAMP is a cAMP analogue used for labelling of cAMP receptors. ε-cAMP can be fluorescent through immobilization by UV light illumination, which offers a label for cAMP receptors. Synonyms: 8-Azido-1,N6-ethenoadenosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. CAS No. 60902-12-7. Molecular formula: C12H10N8O6P. Mole weight: 394.24. | |
| 8-(N-Acetylamino-L-arginine)-goserelin | 8-(N-Acetylamino-L-arginine)-goserelin is an impurity of Goserelin, a luteinizing hormone-releasing hormone analog that mediates the release of gonadotropins. Goserelin can be used to treat prostate cancer and breast cancer. Synonyms: H-Pyr-His-Trp-D-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro(Ac)-NHNHCONH2; (S)-N-((9S,12S,15R,18S,21S,24S,27S)-24-((1H-indol-3-yl)methyl)-15-(tert-butoxymethyl)-9-((S)-2-(2-carbamoylhydrazinecarbonyl)pyrrolidine-1-carbonyl)-18-(4-hydroxybenzyl)-21-(hydroxymethyl)-28-(1H-imidazol-5-yl)-4-imino-12-isobutyl-2,11,14,17,20,23,26-heptaoxo-3,5,10,13,16,19,22,25-octaazaoctacosan-27-yl)-5-oxopyrrolidine-2-carboxamide. Molecular formula: C61H86N18O15. Mole weight: 1311.47. | |
| 8-NBD-cAMP | 8-NBD-cAMP is a fluorescent activator (λexc471 nm, λem536 nm) of cAMP-dependent protein kinase. 8-NBD-cAMP fluoresces strongly in hydrophobic environments. Synonyms: 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio)adenosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 221905-51-7. Molecular formula: C18H17N9NaO9PS. Mole weight: 589.41. | |
| 8-NBD-cGMP | 8-NBD-cGMP is a fluorescent activator of both isozymes I α and I β of cGMP-dependent protein kinase. 8-NBD-cGMP fluoresces strongly in hydrophobic environments. Synonyms: 8-(2-[7-Nitro-4-benzofurazanyl]aminoethylthio)guanosine-3',5'-cyclic monophosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 115993-88-9. Molecular formula: C18H17N9NaO10PS. Mole weight: 605.41. | |
| 8-NH2-ADP | 8-NH2-ADP is an analogue of adenosine-5'-O-diphosphate used in receptor mapping studies. Synonyms: 8- Aminoadenosine- 5'- O- diphosphate. Grade: ≥ 95% by HPLC. CAS No. 65312-53-0. Molecular formula: C10H16N6O10P2 (free acid). Mole weight: 442.2 (free acid). | |
| 8-NH2-ATP | 8-NH2-ATP is an analogue of adenosine-5'-triphosphate and a metabolite of the cytotoxic nucleoside 8-aminoadenosine that can be used for receptor mapping purposes. Synonyms: 8- Aminoadenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 35874-49-8. Molecular formula: C10H17N6O13P3 (free acid). Mole weight: 522.2 (free acid). | |
| 8-Nitroguanine | 8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents. Synonyms: 2-Amino-8-nitro-7H-purin-6-ol. Grade: ≥95%. CAS No. 168701-80-2. Molecular formula: C5H4N6O3. Mole weight: 196.1. | |
| 8-Nitroguanosine | A highly reactive redox-active nucleic acid derivative that is formed in cellular RNA as biomarker of exposure to reactive nitrogen species. Recent studies suggest that it might contribute to the pathogenesis of inflammation-associated carcinogenesis. Synonyms: 8-Nitro-D-guanosine; 2-imino-8-nitro-9-(beta-D-ribofuranosyl)-3,9-dihydro-2H-purin-6-ol; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-nitro-1H-purin-6(9H)-one. Grade: ≥95%. CAS No. 337536-53-5. Molecular formula: C10H12N6O7. Mole weight: 328.24. | |
| 8-Nitroguanosine 2',3',5'-Triacetate | 8-Nitroguanosine derivative. Used as chemical probes in protein S-guanylation by endogenous nitrated nucleosides. Synonyms: 8-Nitroguanosine 2',3',5'-Triacetate; 1096020-95-9; [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2-amino-8-nitro-6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl acetate; (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2-amino-8-nitro-6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate; J-002308; [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2-amino-8-nitro-6-oxo-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methyl acetate. CAS No. 1096020-95-9. Molecular formula: C16H18N6O10. Mole weight: 454.35. | |
| 8-(N,N-Dimethylaminomethyl)guanosine | 8-(N,N-Dimethylaminomethyl)guanosine is a profound compound, aiding in studying the unparalleled menace of herpes simplex virus (HSV) and human cytomegalovirus (HCMV). Grade: ≥95%. Molecular formula: C13H20N6O5. Mole weight: 340.34. | |
| 8-NO2-Guo | 8-NO2-Guo is used for analysis of hydrolysates of RNA stressed by nitric oxide/superoxide and peroxynitrite. Synonyms: 8- Nitroguanosine. Grade: ≥ 98% by HPLC. CAS No. 337636-63-6. Molecular formula: C10H12N6O7. Mole weight: 328.3. | |
| 8-O-Demethyl Ivabradine HCl | 8-O-Demethyl Ivabradine HCl is a pharmaceutical compound meticulously employed in the research of diverse cardiovascular diseases. Its distinctive mechanism of action is acting as a selective inhibitor of the hyperpolarization-activated cyclic nucleotide-gated channel is allows for the proficient modulation of heart rate and commendable enhancement of cardiac function. Synonyms: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-8-hydroxy-7-methoxy-2H-3-benzazepin-2-one HCl. Grade: > 95%. Molecular formula: C26H35ClN2O5. Mole weight: 491.03. | |
| 8-OH-2'-O-Me-cAMP | 8-OH-2'-O-Me-cAMP is an activator of the exchange protein activated by cAMP (Epac) or cAMP-GEF, which does not activate protein kinase A. It can be used in patch clamp applications. Synonyms: 8- Hydroxy- 2'- O- methyladenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. Molecular formula: C11H13N5O7P · Na. Mole weight: 381.2. | |
| 8-OH-Ado | 8-OH-Ado is used for analysis of oxidative/radioactive stress RNA hydrolysates. Synonyms: 8- Hydroxyadenosine. Grade: ≥ 97% by HPLC. CAS No. 29861-67-8. Molecular formula: C10H13N6O6. Mole weight: 283.3. | |
| 8-OH-cAMP | 8-OH-cAMP is a polar analogue of cAMP used for the study of extracellular cAMP receptors. When applied by patch clamp techniques, 8-OH-cAMP remains trapped inside the cell. It exhibits a resistant effect of mammalian cyclic nucleotide-dependent phosphodiesterases. Synonyms: 8- Hydroxyadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 31356-95-3. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2. | |
| 8-OH-cGMP | 8-OH-cGMP is a cyclic guanosine monophosphate (cGMP) analog used in biomedical research. It acts as a second messenger in signal transduction pathways. 8-OH-cGMP is mainly utilized for studying the role of cGMP in various cellular processes, including smooth muscle relaxation, cell proliferation, and neurotransmission. It is also commonly used to investigate the pathophysiology and potential therapeutic targets in diseases related to altered cGMP signaling, such as hypertension, cardiovascular disorders, and neurodegenerative diseases. Synonyms: 8- Hydroxyguanosine- 3', 5'- cyclic monophosphate. CAS No. 21082-28-0. Molecular formula: C10H11N5O8P · Na. Mole weight: 383.2. | |
| 8-OH-DPAT | 8-OH-DPAT (8-Hydroxy-DPAT) is an agonist that has selectivity for 5-HT1A receptor (pIC50 = 8.19). It was subsequently found to be a serotonin reuptake inhibitor and a 5-HT7 receptor agonist as well. Studies showed that it exhibited antidepressant, anxiolytic and other properties. Uses: Serotonin receptor agonists. Synonyms: 8-HYDROXY-2-(DI-n-PROPYLAMINO)TETRALIN; 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; CHEMBL56; Ro-31-8220 in solution; 8-Hydroxy-DPAT. Grade: 99.03 %. CAS No. 78950-78-4. Molecular formula: C16H25NO. Mole weight: 247.38. | |
| 8-Oxo-2'-deoxyadenosine | 8-Oxo-2'-deoxyadenosine is a crucial product in the biomedical industry used for studying and treating oxidative DNA damage caused by reactive oxygen species. It is a modified form of the nucleoside adenosine and serves as a biomarker for DNA damage and oxidative stress-related diseases like cancer, neurodegenerative disorders, and cardiovascular diseases. Synonyms: 2'-Deoxy-8-oxo-adenosine; 8-Oxo-dA; 6-AMINO-9-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-7H-PURIN-8-ONE; 8-Oxo-7,8-dihydro-2'-deoxyadenosine; 8-Oxo-deoxyadenosine; 8-hydroxy-2'-deoxyadenosine; 6-amino-9-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-7H-purin-8-one. Grade: ≥ 95%. CAS No. 62471-63-0. Molecular formula: C10H13N5O4. Mole weight: 267.24. | |
| 8-Oxo-2'-deoxyadenosine-13C2,15N | Isotope labelled 8-Oxo-2'-deoxyadenosine, the first example of a native DNA lesion that stabilizes human telomeric G-quadruplex DNA. Synonyms: 2'-Deoxy-7,8-dihydro-8-oxo-adenosine-13C2,15N; 2'-Deoxy-7,8-dihydroadenosin-8-one-13C2,15N; 7,8-Dihydro-8-oxodeoxyadenosine-13C2,15N; 8-Oxo-7,8-dihydro-2'-deoxyadenosine-13C2,15N. Grade: 95%; >90% atom 13C, 15N. Molecular formula: C8[13C]2H13N4[15N]O4. Mole weight: 270.22. | |
| 8-Oxo-2'-deoxyguanosine | 8-Oxo-2'-deoxyguanosine is a crucial biomarker to evaluate oxidative DNA damage in research of related diseases such as cancer and neurodegenerative disorders. It is an oxidized nucleoside known for its ability to accurately measure the level of oxidative stress. Synonyms: 8-Oxo-dG; 8-Hydroxy-2'-deoxyguanosine; 8-Hydroxydeoxyguanosine. Grade: ≥ 98%. CAS No. 88847-89-6. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
| 8-Oxo-2'-deoxyguanosine-13C,15N2 5'-Triphosphate Triethylamine Salt | 8-Oxo-2'-deoxyguanosine-13C,15N2 5'-Triphosphate is labelled 8-Oxo-2'-deoxyguanosine-5'-Triphosphate which is considered mutagenic dNTPs that can be incorporated into DNA by PCR using standard Taq polymerase. Synonyms: 8-Oxo-7,8-dihydro-2'-deoxyguanosine-13C,15N2 5'-triphosphate; 8-Oxo-dGTP-13C,15N2 Triethylamine Salt; 8-Oxo-deoxyguanosine-13C,15N2 triphosphate Triethylamine Salt. Molecular formula: C9[13C]H16N3[15N]2O14P3 xC6H15N. Mole weight: 526.16. | |
| 8-Oxo-2'-deoxyguanosine 5'-Triphosphate Triethylamine Salt | 8-Oxo-2'-deoxyguanosine-5'-Triphosphate, considered mutagenic dNTPs, it can be incorporated into DNA by PCR using standard Taq polymerase. Synonyms: 2'-Deoxy-7,8-dihydro-8-oxo-guanosine 5'-(tetrahydrogen triphosphate) Triethylamine Salt; 8-Hydroxy-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate Triethylamine Salt; 8-Oxo-dGTP Triethylamine Salt; 8-Oxo-deoxyguanosine triphosphate Triethylamine Salt. Molecular formula: C10H16N5O14P3 xC6H15N. Mole weight: 523.18. | |
| 8-Oxoadenoosine-5'-Triphosphate | 8-Oxoadenosine-5'-Triphosphate, an ATP analog crucial for cell signaling and energy transfer, is integral to studying signal transduction pathways and disease mechanisms. It also aids in the DNA sequencing and mutagenesis studies through its ability to incorporate into DNA strands. Its widespread use in research has contributed to unravelling the mysteries hidden within cancer, inflammation, and neurological disorders. Synonyms: 8-Oxo-ATP; 8-Oxo-Adenosine-5'-Triphosphate. Grade: ≥95% by AX-HPLC. CAS No. 68745-44-8. Molecular formula: C10H16N5O14P3. Mole weight: 523.10. | |
| 8-Oxoadenosine | It is an anticancer antibiotic, oxidized nucleic acid adduct and phosmidosine precursor (P-prodrug). It can be used to treat hemochromatosis. Synonyms: NSC 102240; NSC 90396; 7,8-Dihydro-8-oxoadenosine; 8-Hydroxyadenosine; 8-Oxo-7,8-dihydroadenosine; 6-Amino-7,9-dihydro-9-β-D-ribofuranosyl-8H-purin-8-one; 6-amino-9-(beta-D-ribofuranosyl)purin-8-(7H)-one; (2R,3R,4S,5R)-2-(6-amino-8-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Hydroxyadenosine. Grade: ≥95%. CAS No. 29851-57-8. Molecular formula: C10H13N5O5. Mole weight: 283.24. | |
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