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Nicarbazin
Nicarbazine is used as a preventive anticoccidial drug in chicken feed. It can reduce the egg hatching rate of urban bird pest species. Uses: Coccidiostats. Synonyms: Nicarbazine; Nicoxin; Nicrazin. Grades: >95%. CAS No. 330-95-0. Molecular formula: C19H18N6O6. Mole weight: 426.38.
Niddamycin
It is a new macrolide antibiotic produced by the strain of Str. rimosus NRRL 3016. Niddamycin is resistant to gram-positive bacteria. Synonyms: 3-Desacetylcarbomycin-B; 9-Deoxy-9-oxoleucomycin V 4B (3-methylbutanoate); F-3463. Grades: ≥98%. CAS No. 20283-69-6. Molecular formula: C40H65NO14. Mole weight: 783.94.
Nidulin
Nidulin is produced by the strain of Asp. nidulans NRRL 2006. It is resistant to mycobacterium but not very effective. Synonyms: Methylustin; O-Methylustin; 4,2-Cresotic acid, 3,5-dichloro-6-(5-chloro-2-hydroxy-4-methoxy-6-(1-methylpropenyl)-m-tolyloxy)-, epsilon-lactone. CAS No. 1329-04-0. Molecular formula: C20H17Cl3O5. Mole weight: 443.70.
Nifalatide
Nifalatide is a gastrointestinal compound. Synonyms: L-Tyrosyl-S-oxido-D-methionylglycyl-4-nitro-L-phenylalanyl-L-prolinamide. Grades: >98%. CAS No. 73385-60-1. Molecular formula: C30H39N7O9S. Mole weight: 673.74.
Nigerloxin
It is originally isolated from Aspergillus niger CFR-W-105. Nigerloxin inhibited the activity of rat lens aldose reductase (RLAR) and lipid oxidase (LOX-1) with IC50 of 69 μmol/L and 79 μmol/L, respectively. Molecular formula: C13H15NO5. Mole weight: 265.26.
Nikkomycin Lx
Nikkomycin Lx is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components. Molecular formula: C21H27N5O9. Mole weight: 493.47.
Nikkomycin Lz
Nikkomycin Lz is originally isolated from Streptomyces tendae TU901. Although it is a microcomponent, it is relatively stable and has stronger anti-candida albicans activity than other components. Molecular formula: C20H25N5O9. Mole weight: 479.44.
H-His(Trt)-OMe Hydrochloride is used to prepare Nα-methyl-Nα-(nitrobenzenesulfonyl)amino acids and their incorporation into dipeptides. It is also used to synthesize azaproline-based peptide analogs of TRH. Synonyms: L-His(Trt)-OMe HCl; methyl(2S)-2-amino-3-(1-tritylimidazol-4-yl)propanoate hydrochloride; H-His(Trt)-OMe. Grades: ≥ 99.5% (HPLC). CAS No. 32946-56-8. Molecular formula: C26H25N3O2·HCl. Mole weight: 448.00.
Niphimycin is an antimicrobial metabolized from Streptomyces. Synonyms: Scopafungin. CAS No. 11056-18-1. Molecular formula: C59H103N3O18. Mole weight: 1142.45.
Nisamycin
Nisamycin is originally isolated from Str. sp. K106. It has stronger anti-gram-positive bacteria and weaker anti-fungal and individual gram-negative bacteria activities. And it has weak cytotoxic effect. The IC50 of mouse leukemia P388 cells was 4.8 μg/mL. Synonyms: 2,4,6-Heptatrienoic acid, 7-(4-((5-cyclohexyl-1-oxo-2,4-pentadienyl)amino)-2-hydroxy-5-oxo-7-oxabicyclo(4.1.0)hept-3-en-2-yl)-, (1S-(1alpha, 2beta, 2(2E, 4E, 6E), 4(2E, 4E), 6alpha))-. CAS No. 150829-93-9. Molecular formula: C24H27NO6. Mole weight: 425.47.
Nitroarginine
Nitroarginine, or Nω-nitro-L-arginine, is a nitro derivative of the amino acid arginine. It is an inhibitor of nitric oxide synthase and hence a vaso-constrictor and coronary constrictor. As such, it finds widespread use as a biochemical tool in the study of nitric oxide and its biological effects. Nitroarginine has been used in research studying coronary constriction, in the presence of midazolam vasodilatation was unaffected by nitroarginine. Nitroarginine is currently in clinical trials for treating patients with advanced solid tumors. Uses: Enzyme inhibitors. Synonyms: Nitroarginine; N5-(nitroamidino)-L-Ornithine; (+)-NG-Nitroarginine; NG-nitro-L-Arginine, L-NG-Nitroarginine; L-NNA; L-NOARG; NG-Nitro-L-arginine; NG-Nitroarginine; NOLA; NSC 53662; NSC-53662; NSC53662; Nitro-L-arginine; Nω-Nitro-L-arginine; Nω-Nitro-L-arginine; ω-Nitro-L-arginine; ω-Nitroarginine. Grades: >98%. CAS No. 2149-70-4. Molecular formula: C6H13N5O4. Mole weight: 219.20.
Nitroferroin
Nitroferroin is a high potential oxidation-reduction indicator. Synonyms: 5-Nitro-1,10-Phenanthroline. CAS No. 4199-88-6. Molecular formula: C12H7N3O2. Mole weight: 225.20.
NK 1001
NK 1001 is produced by the strain of Streptomyces kanamyceticus var. NK 1001 has weak activity against gram-positive, gram-negative and mycobacterium bacteria. Synonyms: Antibiotic NK 1001; 4,6-Diamino-3-(hexopyranosyloxy)-2-hydroxycyclohexyl 6-amino-6-deoxyhexopyranoside. CAS No. 53025-93-7. Molecular formula: C18H35N3O12. Mole weight: 485.48.
NK-1013-1
NK-1013-1 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive bacteria. Synonyms: Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-N(sup 3)-acetyl-, D-. CAS No. 102612-61-3. Molecular formula: C20H38N4O13. Mole weight: 542.5.
NK-1013-2
NK-1013-2 is an aminoglycoside antibiotic isolated from Streptomyces kanamyceticus var.21-16. It is active against gram-positive and gram-negative bacteria. Molecular formula: C22H40N4O14. Mole weight: 584.6.
NK10958P
NK10958P is a plant growth regulator produced by Streptomyces sp. NK10958. Synonyms: NK-10958P. Molecular formula: C18H30O4. Mole weight: 310.4.
NK 154183A
NK 154183A is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183A; (4E, 18E)-11, 12, 13, 14, 16, 17, 27a-Heptahydroxy-6'-(2-hydroxybutyl)-2, 2, 11, 15, 17, 28-hexamethyl-2, 3, 3', 3a, 4', 5', 6, 6', 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 26, 27, 27a-tetracosahydro-20H-spiro[22, 26-methanofuro[2, 3-h][1, 5]dioxacyclohexacosine-24, 2'-pyran]-20-one. CAS No. 152986-47-5. Molecular formula: C41H70O13. Mole weight: 771.
NK 154183B
NK 154183B is a 24-membered macrolide antibiotic isolated from the fermentation broth of Streptomyces sp. NK154183. It exhibits antifungal and antitumor activity against the human colon adenocarcinoma. Synonyms: NK154183B; (4E, 18E)-13-{[5-(Dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-11, 12, 14, 16, 17, 27a-hexahydroxy-6'-(2-hydroxybutyl)-2, 2, 11, 15, 17, 28-hexamethyl-2, 3, 3', 3a, 4', 5', 6, 6', 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 22, 23, 26, 27, 27a-tetracosahydro-20H-spiro[22, 26-methanofuro[2, 3-h][1, 5]dioxacyclohexacosine-24, 2'-pyran]-20-one. CAS No. 152986-49-7. Molecular formula: C49H85NO14. Mole weight: 912.2.
NK30424A
NK30424A is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 1 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8.
NK30424B
NK30424B is an inhibitor of lipopolysaccharide-induced tumour necrosis factor alpha production with IC50 value of 0.9 μmol/L. It is produced by Streptomyces sp. NA30424. Molecular formula: C30H46N2O10S. Mole weight: 626.8.
Prolyl-histidine is a dipeptide composed of proline and histidine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-Pro-His-OH; H-PH-OH; L-prolyl-L-histidine; Prolyl-Histidine; L-Histidine, L-prolyl-; (S)-3-(1H-Imidazol-4-yl)-2-((S)-pyrrolidine-2-carboxamido)propanoic acid; N-prolyl histidine. Grades: ≥95%. CAS No. 92027-43-5. Molecular formula: C11H16N4O3. Mole weight: 252.27.
N-Methyl-L-alanine is a reactant used in the preparation of site-specific trastuzumab maytansinoid antibody-drug conjugates with improved therapeutic activity. Synonyms: N-Me-L-Ala-OH HCl; N-Methyl-L-alanine; (2S)-2-(methylamino)propanoic acid. Grades: ≥ 98% (TLC). CAS No. 3913-67-5. Molecular formula: C4H9NO2·HCl. Mole weight: 139.62.
N-Methylstreptothricin F is a streptomycin antibiotic produced by Actinomyces sp. A37812. It has good antibacterial activity against Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae. Synonyms: A 37812. Grades: >98%. CAS No. 99237-10-2. Molecular formula: C20H36N8O8. Mole weight: 516.55.
N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate is a reagent used in the preparation of hindered Barton esters from hindered carboxylic acid precursors. N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiouronium Hexafluorophosphate is also used as a coupling reagents for peptide bond formations and amidation reactions. Synonyms: S-(1-OXIDO-2-PYRIDYL)-N,N,N',N'-TETRAMETHYLTHIURONIUM-PF6; N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuron; S-(1-Oxido-2-pyridyl)-N,N,N',N'-tetramethylthiuron; HOTT N,N,N'',N''-TETRAMETHYL-S-(1-OXIDO-2-PYRIDYL)THIURONIUM HEXAFLUOROPHOSPHATE; HOTT; S-(2-Pyridyl)-N,N,N',N'-tetramethylthiuronium N-oxide hexafluorophosphate; hott; AmbotzRL-1156; S-(1-Oxido-2-pyridinyl) 1,1,3,3-tetramethylthiouronium Hexafluorophosphate. Grades: 98%. CAS No. 212333-72-7. Molecular formula: C10H16F6N3OPS. Mole weight: 371.28.
No. 17927 D
No. 17927 D is a beta-lactam antibiotic produced by Streptomyces fulvoviridis SANK 61278, SANK 60183 and SANK 69283. The antibacterial activity is weak. Molecular formula: C13H19N2O5SNa. Mole weight: 338.35.
It is a polyether antibiotic produced by the strain of Str. noboritoensis NRRL 8123. Noboritomycin A has the effect of anti-gram-positive bacteria. Grades: >98%. CAS No. 68508-45-2. Molecular formula: C43H64O14. Mole weight: 804.96.
Nocamycin
Nocamycin is produced by the strain of Nocandiopsis syringae sp. nov. and it has anti-tumor effect. Synonyms: 3-[6-(2,5-Dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)-1,3-dimethyl-6-oxohexa-2,4-dienyl]-α,1,4-trimethyl-6-oxospiro[2,9-dioxabicyclo[3.3.1]nonane-8,2'-oxirane]-3'-acetic acid methyl ester. Grades: ≥98%. CAS No. 63748-09-4. Molecular formula: C26H33NO9. Mole weight: 503.54.
Nocamycin I
Bu-2313B is an anti-anaerobic antibiotic produced by Microtetraspora caesia. It has broad-spectrum anti-gram-positive and negative anaerobic activity. Synonyms: (-)-nocamycin I; Antibiotic BU 2313B; BU-2313B. CAS No. 69774-87-4. Molecular formula: C26H33NO9. Mole weight: 503.54.
Nocardicyclin A
It is produced by the strain of Nocardia pseudobrasiliensis IFM 0624. Nocardicyclin A is resistant to gram-positive bacteria, mycobacterium and Nocardia and it is more active than B. Synonyms: 1,6,11(2H)-Naphthacenetrione, 3,4-dihydro-3,10-dimethoxy-2-methyl-4-((2,3,6-trideoxy-3-(dimethylamino-3-C-methyl-alpha-lyxo-hexopyranosyl)oxy)-2,5,7-trihydroxy-, (2R,3R,4R)-rel-. Grades: >98% by HPLC. CAS No. 199173-81-4. Molecular formula: C30H35NO11. Mole weight: 585.60.
Nocardicyclin B
It is produced by the strain of Nocardia pseudobrasiliensis IFM 0624. Nocardicyclin B is resistant to gram-positive bacteria, mycobacterium and Nocardia. Molecular formula: C32H37NO12. Mole weight: 627.63.
Nocathiacin I
Nocathiacin I is produced by the strain of Nocardia sp. WW-12651. It is highly resistant to gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP) and multidrug resistant Enterococcus faecalis (MREF). Molecular formula: C61H60N14O18S5. Mole weight: 1437.53.
It is an antibiotic produced by the strain of Saccharopolyspora hirsuta and Nocardia argentinensis. It is a co-metabolite of nargenicin, bearing the core macrocyclic lactone but lacking the pyrrole ester. It has anti-gram-positive bacteria and anaerobic bacteria activity. Synonyms: Antibiotic U 59761; Nodusmicin 1; [3R-[1E, 3R*, 4S*(R*), 7S*, 8aS*, 10aR*, 11R*, 12R*, 13R*, 14R*, 14aS*, 14bS*]]-3, 4, 8, 8a, 10a, 11, 12, 13, 14, 14a-Decahydro-12, 14-dihydroxy-4-(1-hydroxyethyl)-7-methoxy-1, 3, 13-trimethyl-11, 14b-epoxy-14bH-naphth[2, 1-e]oxecin-6(7H)-one; (1E, 3R, 4S, 7S, 8aS, 10aR, 11R, 12R, 13R, 14R, 14aS, 14bS)-3, 4, 8, 8a, 10a, 11, 12, 13, 14, 14a-decahydro-12, 14-dihydroxy-4-[(1R)-1-hydroxyethyl]-7-methoxy-1, 3, 13-trimethyl-11, 14b-epoxy-14bH-naphth[2, 1-e]oxecin-6(7H)-one; U 59761. Grades: >99% by HPLC. CAS No. 76265-48-0. Molecular formula: C23H34O7. Mole weight: 422.51.
Noformicin
Noformicin is produced by the strain of Nocardia formica. It has inhibitory effect on mumps virus and Newcastle disease virus in chicken embryo. It also extended the survival of mice infected with swine, influenza A (PR8) and influenza B (Lee) viruses. Synonyms: (+/-)-Noformicin; DL-Noformicin; 2H-Pyrrole-2-carboxamide, 5-amino-N-(3-amino-3-iminopropyl)-3,4-dihydro-. Grades: 98%. CAS No. 155-38-4. Molecular formula: C8H15N5O. Mole weight: 197.24.
Nogalamycin
An unusual anthracycline produced by streptomyces nogalater var. Nogalater. It is a potent antibacterial and antitumor agent that interacts with DNA by intercalation. Synonyms: U 15167; Antibiotic U 15167; Nogalamicina; Nogalamycinum. Grades: >95% by HPLC. CAS No. 1404-15-5. Molecular formula: C39H49NO16. Mole weight: 787.80.