BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 8-Bromo-3'-deoxy-3'-fluorotoyocamycin | 8-Bromo-3'-deoxy-3'-fluorotoyocamycin is a potent compound used in the research of various cancers and viral infections. Its mechanism of action involves inhibiting nucleic acid enhancement, leading to the suppression of tumor growth and viral replication. CAS No. 2095417-57-3. Molecular formula: C12H11BrFN5O3. Mole weight: 372.15. |  |
| 8-Bromo-3'-deoxyguanosine | 8-Bromo-3'-deoxyguanosine is a remarkable and robust antiviral compound, finding extensive application in research of viral infections, especially those of DNA origin. Synonyms: 2-amino-8-bromo-9-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one. Grade: ≥95%. CAS No. 847649-68-7. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine | 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine is a remarkable pharmaceutical compound with anti-inflammatory and immunomodulatory attributes. Potential applications include the research of various inflammatory ailments like rheumatoid arthritand asthma. Synonyms: 8-Bromo-5'-O-(4-cyanobenzyl)-2',3'-di-O-isopropylidene adenosine; 4-[[(3aR,4R,6R,6aR)-4-(6-amino-8-bromopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxymethyl]benzonitrile; Adenosine, 8-bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-O-(1-methylethylidene)-; 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-O-(1-methylethylidene)adenosine; 4-((((3AR,4R,6R,6aR)-6-(6-amino-8-bromo-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methoxy)methyl)benzonitrile. Grade: ≥95%. CAS No. 1134156-53-8. Molecular formula: C21H21BrN6O4. Mole weight: 501.33. | |
| 8-Bromo-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine | 8-Bromo-5'-O-(dimethoxytrityl)-N6-(dimethylaminomethylidene)-2'-deoxyadenosine, a chemical compound utilized in the production of antiviral and anticancer drugs, has been found to selectively impede the replication of herpes simplex virus and stunt the expansion of cancer cells by hindering their DNA synthesis. Its specificity in targeting these entities makes it a valuable player in the medical field. Its multifaceted properties offer advancements in the development of novel treatments. CAS No. 207906-53-4. Molecular formula: C34H35BrN6O5. Mole weight: 687.60. | |
| 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine | 8-Bromo-5'-O-(dimethyoxytrityl)-N2-(dimethyl-aminomethylidene)-2'-deoxyguanosine, renowned for its unparalleled efficacy, stands as an indispensable entity within the illustrious biomedical realm. Revered for its unrivaled specificity, this miraculous compound has revolutionized the field by combatting DNA viruses with remarkable prowess. Its potency is particularly evident in its success against the notorious herpes simplex virus (HSV) and hepatitis B virus (HBV). Grade: ≥ 97%. CAS No. 204582-53-6. Molecular formula: C34H35BrN6O6. Mole weight: 703.59. | |
| 8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione | An impurity of Linagliptin, a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes. Synonyms: 1-[(4-Methylquinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-bromoxanthine; 8-Bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione; Linagliptin Impurity A. Grade: 98%. CAS No. 853029-57-9. Molecular formula: C20H17BrN6O2. Mole weight: 453.29. | |
| 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine | 8-Bromo-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-2'-deoxy-b-D-ribofuranosyl]guanine is an innovative compound, holding immense potential in studying a range of viral infections, with its primary focus lying on DNA viruses. Molecular formula: C22H38BrN5O5Si2. Mole weight: 588.64. | |
| 8-Bromo-9-(b-D-xylofuranosyl)guanine | 8-Bromo-9-(b-D-xylofuranosyl)guanine is an extraordinary antiviral compound bestowed with remarkable potentiality for research of viral infections, specifically focused on herpes viruses. By selectively concentrating on the viral DNA polymerase, it effectively restrains viral DNA enhancement. Synonyms: 6H-Purin-6-one, 2-amino-8-bromo-1,9-dihydro-9-β-D-xylofuranosyl-; 2-amino-8-bromo-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one; 8-bromguanosine; 2-Amino-8-bromo-9-(β-D-xylofuranosyl)-1,9-dihydro-6H-purin-6-one. Grade: ≥95%. CAS No. 1212650-12-8. Molecular formula: C10H12BrN5O5. Mole weight: 362.14. | |
| 8-Bromoadenine-13C2,15N2 | 8-Bromoadenine-13C2,15N2 is the isotope labelled analog of 8-Bromoadenine, a compound when injected into mice before exposure to irradiation, increased the radiosensitivity of bone marrow hemopoietic stem cells. Synonyms: 6-Amino-8-bromopurine-13C2,15N2; 8-Bromo-9H-purin-6-amine-13C2,15N2; 8-Bromo-1H-purin-6-amine-13C2,15N2; NSC 21697-13C2,15N2. Molecular formula: C3[13C]2H4BrN3[15N]2. Mole weight: 217.99. | |
| 8-Bromoadenosine | 8-Bromoadenosine is an adenosine binding inhibitor. 8-Bromoadenosine is a modified nucleoside with a bromine atom at the 8-position of the adenine base. It is used in biochemical research to study nucleic acid structure and function, and to investigate interactions between nucleic acids and proteins. Synonyms: 8-Bromo-ribo Adenosine; 6-Amino-8-bromopurine Riboside; NSC 79213; 8-Bromo Adenosine; (2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; Bromoadenosine; 8-Bromo-adenosine; 8-Bromoadenine-9-β-D-ribofuranoside. Grade: ≥97% by HPLC. CAS No. 2946-39-6. Molecular formula: C10H12BrN5O4. Mole weight: 346.14. | |
| 8-Bromoadenosine 3',5'-Cyclic Monophosphate Sodium Salt Monohydrate | 8-Bromoadenosine 3',5'-Cyclic Monophosphate Sodium Salt Monohydrate is a biochemical which promotes cell division. Synonyms: 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT HYDRATE; 8-BROMOADENOSINE 3',5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM SALT MONOHYDRATE; 8-bromoadenosine 3',5'-cyclic monophos-phoric aci; 8-BROMOADENOSINE 3',5'-CYCLIC MONOPHOS-P HORIC ACID, NA SALT MONO. Grade: 95%. CAS No. 123334-12-3. Molecular formula: C10H10BrN5NaO6P H2O. Mole weight: 430.08. | |
| 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt | 8-Bromoadenosine 3',5'-Cyclic Monophosphothioate Sp-Isomer Sodium Salt is an activator of cAMP-dependent PKA. Synonyms: 1573115-90-8; Rp-8-bromo-Cyclic AMPS (sodium salt); 8-Bromoadenosine 3',5'-cyclic monophosphothiaoate, Sp-isomer sodium salt; Rp-8-bromo-Cyclic AMPS; 127634-20-2; Sp-8-bromo-Cyclic AMPS (sodium salt); sodium; (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-sulfanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol; 8-Bromoadenosine3',5'-CyclicMonophosphothioateSp-IsomerSodiumSalt; 8-bromo-adenosinecyclic3',5'-[hydrogen[P(R)]-phosphorothioate],monosodiumsalt; Rp-8-bromo-Cyclic AMPS sodium salt; Rp-8-Br-cAMPS; Rp-8-bromo-cAMPS; 8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer; Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-sulfanylidene-hexahydro-2|E-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate; Sodium [(2R,4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)-7-hydroxy-2-oxo-hexahydro-2|E-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl]sulfanide. CAS No. 1573115-90-8. Molecular formula: C10H10BrN5NaO5PS. Mole weight: 446.15. | |
| 8-Bromoadenosine 5'-Triphosphate Sodium Salt | 8-Bromoadenosine 5'-Triphosphate Sodium Salt is a reagent required for the characterization (stoichiometry, geometry, and stability constant) of ATP:Fe(II) complex. Synonyms: 8-bromo-adenosine-5'-triphosphate, sodium salt; 8-Br-ATP, Sodium Salt; 8-Bromo-adenosine 5'-(Tetrahydrogen triphosphate) Sodium Salt; Adenosine 5'-(tetrahydrogen triphosphate), 8-bromo-, sodium salt; 8-Bromo-ATP sodium salt. Grade: ≥95% by HPLC. CAS No. 81035-56-5. Molecular formula: C10H15BrN5O13P3 (free acid). Mole weight: 586.08 (free acid). | |
| 8-Bromo-ADP | 8-Bromo-ADP is a remarkable effector on purinergic receptors, which play vital roles in numerous intricate intracellular signaling cascades. This compound offering an invaluable avenue to probe the intricate repercussions of purinergic receptor activation on diverse cellular functionalities. Synonyms: (8Br-ADP); 8-Bromo-adenosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 23600-16-0. Molecular formula: C10H14N5O10P2Br (free acid). Mole weight: 506.10 (free acid). | |
| 8-Bromo-AMP | 8-Bromo-AMP, a pharmaceutical compound widely employed in the biomedical sector, holds significant importance in the exploration and management of diverse diseases. As a derivative of adenosine monophosphate (AMP), it possesses altered characteristics that play a pivotal role in cellular metabolism and signaling. Moreover, owing to its utilization in signal transduction pathway investigations and assessment of adenylyl cyclase activation effects, 8-Bromo-AMP showcases its versatility. Synonyms: (8Br-AMP); 8-Bromo-adenosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 23567-96-6. Molecular formula: C10H13BrN5O7P (free acid). Mole weight: 426.12 (free acid). | |
| 8-Bromo-AP2 (Nic) | 8-Bromo-AP2 (Nic) unlocks the potential for therapeutic intervention in multiple neurological disorders, including Alzheimer's disease and nicotine addiction, thanks to its potent and selective inhibitory effects on the nicotinic acetylcholine receptor. In addition to its clinical applications, this compound serves as a research tool for the in-depth study of nicotinic receptors within the complex biological framework of the brain. Synonyms: (8Br-AP2(Nic)); Nicotinamide 8-bromo-adenine dinucleotide, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C21H26BrN7O14P2 (free acid). Mole weight: 742.32 (free acid). | |
| 8-Bromo-AppNHp | 8-Bromo-AppNHp, a coveted biochemical compound, brimming with potential, is considered an integral tool in the unprecedented scientific endeavors to unravel the mysteries of signal transduction and protein activation pathways. Its significance lies in its extraordinary ability to emulate adenosine triphosphate (ATP), lending an unfiltered glimpse into the functional intricacies of G-proteins and adenylate cyclases. Its presence has revolutionized the world of medicinal research, opening new horizons in the quest to tackle both neurological disorders and cardiovascular diseases. Synonyms: (8Br-AppNHp, 8Br-AMPPNP); 8-Bromo-adenosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H16N6O12P3Br (free acid). Mole weight: 585.09 (free acid). | |
| 8-Bromo-ATP | 8-Bromo-ATP is a potent analog of adenosine triphosphate (ATP), a crucial energy carrier in cells. Widely used in biomedicine, 8-Bromo-ATP exhibits high affinity towards purinergic receptors and is often employed to study their function and signaling pathways. Additionally, this compound serves as a substrate for various enzymatic reactions, enabling researchers to investigate ATP-dependent processes in drug discovery and disease mechanisms. Synonyms: 8-Bromoadenosine 5'-Triphosphate; (8Br-ATP); 8-Br-ATP; 8-Bromoadenosine 5'-(tetrahydrogen triphosphate); Adenosine, 8-bromo-, 5'-(tetrahydrogen triphosphate); 8-Bromo ATP; 8-Bromoadenosine triphosphate; ((2R,3S,4R,5R)-5-(6-Amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate. Grade: ≥95% by HPLC. CAS No. 23567-97-7. Molecular formula: C10H15BrN5O13P3. Mole weight: 586.08. | |
| 8-Bromo-cAMP sodium salt | 8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. It inhibits cell growth, decreases proliferation, increases differentiation and induces apoptosis. Synonyms: 8-Br-3',5'-cyclo-adenosine monophosphate, sodium salt; 8-Br-3',5'-cyclo-AMP.Na; (8Br-cAMP) sodium salt; 8-Bromo-adenosine-3',5'-cyclic monophosphate, Sodium salt; 8-Br-cAMP sodium salt; 8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt; Adenosine, 8-bromo-, cyclic 3',5'-(hydrogen phosphate), sodium salt (1:1). Grade: 95%. CAS No. 76939-46-3. Molecular formula: C10H10BrN5NaO6P. Mole weight: 430.08. | |
| 8-Bromo-dATP | 8-Bromo-dATP is a nucleoside triphosphate analog primarily used in research to investigate DNA damage and repair mechanisms. It can be incorporated into DNA during replication, leading to altered DNA structure and function. Synonyms: (8Br-dATP); 8-Bromo-2'-deoxyadenosine-5'-triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 92410-99-6. Molecular formula: C10H15N5O12P3Br (free acid). Mole weight: 570.08 (free acid). | |
| 8-Bromo-GDP | 8-Bromo-GDP is an exemplary and formidable analogue of guanosine diphosphate (GDP), facilitating the research of GTP-binding proteins and the mechanisms of signaling pathways, protein enmeshment and GTPase activity. Synonyms: (8Br-GDP); 8-Bromo-guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H14N5O11P2Br (free acid). Mole weight: 522.09 (free acid). | |
| 8-Bromo-GMP | 8-Bromo-GMP is a compound used in biomedicine to study the effects of G protein-coupled receptor signaling and phosphodiesterase activity. It has also been studied for its anticancer properties due to its ability to induce cell death in various cancer cell lines. Additionally, 8-Bromo-GMP has been used to mimic the effects of nitric oxide signaling in biological processes. Synonyms: (8Br-GMP); 8-Bromo-guanosine-5'-monophosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H13N5O8PBr (free acid). Mole weight: 442.11 (free acid). | |
| 8-Bromo-GppNHp | 8-Bromo-GppNHp, a biochemical known for its role in investigating the signaling pathways of G proteins, is gaining notoriety in the field of biomedical research. Primarily, the product is utilized to study G protein-coupled receptors (GPCRs) and their downstream effectors. Beyond that, the research community has found it to be instrumental in studies related to various diseases -- among them cancer, cardiovascular afflictions, and diabetes. As the product continues to prove its worth, it is sure to remain an increasingly important tool for those in the field of biomedical science. Synonyms: (8Br-GppNHp, 8Br-GMPPNP); 8-Bromo-guanosine-5'-[(β,γ)-imido]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C10H16N6O13P3Br (free acid). Mole weight: 601.09 (free acid). | |
| 8-Bromo-GTP | 8-Bromo-GTP is a GTP analog that can inhibit GTP-hydrolase. It competitively inhibits GTPase (IC50 = 32 μM) and competes with ATP for the binding center of RNA-polymerase. Synonyms: (8Br-GTP); 8-Bromo-guanosine-5'-triphosphate; 8-Bromoguanosine 5'-triphosphate; 8-Bromoguanosine triphosphate. Grade: ≥95% by HPLC. CAS No. 23197-98-0. Molecular formula: C10H15BrN5O14P3. Mole weight: 602.08. | |
| 8-Bromoguanine ( 8-Br-Gua ) | 8-Bromoguanine (8-Br-Gua), a potent and versatile compound widely employed in the field of biomedicine, offers immense potential for treating a myriad of ailments, including cancer, when combined with conventional chemotherapeutic agents. Its unprecedented capability to impede the proliferation of malignant cells has been unequivocally established through comprehensive scientific inquiry, positioning it as an auspicious contender for precise and targeted therapeutic interventions. Synonyms: 2-Amino-8-bromo-6-hydroxypurine; 2-amino-8-bromo-9H-purin-6-ol; 2-amino-8-bromo-1,9-dihydropurin-6-one; 2-amino-8-bromo-3,7-dihydropurin-6-one; 2-Amino-8-bromo-1H-purin-6(7H)-one; 2-Amino-8-bromo-1,7-dihydro-6H-purin-6-one; 2-amino-8-bromopurin-6-ol; NSC 7845. Grade: ≥97% by HPLC. CAS No. 3066-84-0. Molecular formula: C5H4BrN5O. Mole weight: 230.02. | |
| 8-Bromoguanosine | 8-Bromo-guanosine, an extensively studied chemical entity, manifests remarkable potency in the realm of biomedicine owing to its ability to obstruct viral RNA synthesis. Synonyms: 8-Bromo-guanosine; 8-Bromo-ribo Guanosine; 2-Amino-8-bromo-6-hydroxypurine Riboside; NSC 174257; NSC 79211; 2-amino-8-bromo-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; 8-Bromo-D-guanosine; 8-Bromo-9-β-D-ribofuranosylguanine. Grade: ≥98% by HPLC. CAS No. 4016-63-1. Molecular formula: C10H12BrN5O5. Mole weight: 362.14. | |
| 8-Bromoguanosine-13C,15N2 | 8-Bromoguanosine-13C,15N2. Synonyms: 2-Amino-8-bromo-6-hydroxypurine Riboside-13C,15N2; NSC 174257-13C,15N2; NSC 79211-13C,15N2. Grade: 97% by HPLC; 98.9% atom 13C, 15N. Molecular formula: C9[13C]H12BrN3[15N]2O5. Mole weight: 365.12. | |
| 8-Bromoguanosine-13C2,15N | 8-Bromoguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N. 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine, which is a potent inhibitor of purine nucleoside phosphorylase. Synonyms: 2-Amino-8-bromo-6-hydroxypurine Riboside-13C2,15N; NSC 174257-13C2,15N; NSC 79211-13C2,15N. Molecular formula: C8[13C]2H12BrN4[15N]O5. Mole weight: 365.12. | |
| 8-Bromoinsine | 8-Bromoinsine is a remarkably powerful and bioactive compound, embodied within its molecular structure lies a potent antiviral potential, holding great application in restraining the proliferation of diverse viral strains. Synonyms: (2R,3R,4S,5R)-2-(8-bromo-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol. Grade: 95%. CAS No. 55627-73-1. Molecular formula: C10H11BrN4O5. Mole weight: 347.12. | |
| 8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine | 8-Bromo-N2-(dimethylaminomethylidene)-2'-deoxyguanosine is a highly prized compound, holding immense value due to its noteworthy potential in studying tumors and viral drugs. This compound can be used to delve into the intricate repercussions of DNA impairment and the subsequent mechanisms involved in its reparation. Grade: ≥ 90%. CAS No. 717876-75-0. Molecular formula: C13H17BrN6O4. Mole weight: 401.21. | |
| 8-Bromo-N6-benzoyl-dA CEP | The 8-Bromo-N6-benzoyl-dA CEP is an indispensable chemical compound that holds immense significance within the biomedicine industry. This remarkable product serves as a linchpin in the process of developing therapeutic drugs targeted towards tackling a myriad of diseases. It exhibits unparalleled utility in the synthesis of nucleotides and nucleic acid analogs, thereby facilitating revolutionary strides in the realm of anti-cancer and anti-viral treatments. Molecular formula: C47H51BrN7O7P. Mole weight: 936.83. | |
| 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine | 8-Bromo-N6-(dimethylaminomethylidene)-2'-deoxyadenosine is an exceptionally powerful and discriminatory inhibitor, aiding through precise research within distinct enzymatic mechanisms. F. Synonyms: 8-BROMO-N6-(DIMETHYLAMINOMETHYLIDENE)-2'-DEOXYADENOSINE; N'-[8-bromo-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]-N,N-dimethylmethanimidamide. Grade: ≥ 95%. CAS No. 207906-52-3. Molecular formula: C13H17BrN6O3. Mole weight: 385.21. | |
| 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2'-deoxyribofuranosyl]guanine | 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-β-D-2'-deoxyribofuranosyl]guanine is a highly complex compound, standing renowned due to its exceptional antiviral properties. In the pursuit of research of DNA viruses, including herpesviruses, this compound finds its purpose. Through the inhibition of viral DNA replication, it diligently curbs the propagation of viral pathogens. Synonyms: 9-[(6aR,8R,9aR)-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-8-bromo-1H-purin-6-one; 2-Amino-8-bromo-9-[(6aR,8R,9aR)-2,2,4,4-tetra(propan-2-yl)tetrahydro-2H,4H,6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-3,9-dihydro-6H-purin-6-one; 8-Bromo-N9-[3',5'-O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-beta-D-2'-deoxyribofuranosyl]guani; DTXSID10747232; 8-Bromo-N9-[3 inverted exclamation mark ,5 inverted exclamation mark -O-(1,1,3,3-tetrakis(isopropyl)-1,3-disiloxanediyl)-|A-D-2 inverted exclamation mark -deoxyribofuranosyl]guanine. CAS No. 769141-88-0. Molecular formula: C22H38BrN5O5Si2. Mole weight: 588.64. | |
| 8-Br-PET-cGMP | 8-Br-PET-cGMP is a stimulator of isozymes I α and I β of cGMP-dependent protein kinase, which is used as an excellent cyclic nucleotide muscle relaxants. Grade: ≥ 98% by HPLC. CAS No. 144510-04-3. Molecular formula: C18H14BrN5O7P · Na. Mole weight: 546.2. | |
| 8-Br-PET-cGMP Sodium Salt | 8-Br-PET-cGMP Sodium Salt is a pkG cell-permeable activator. Synonyms: 2-Bromo-3,4-dihydro-6-phenyl-3-(3,5-O-phosphinico-β-D-ribofuranosyl)-9H-imidazo[1,2-a]purin-9-one Sodium Salt. CAS No. 185246-29-1. Molecular formula: C18H14BrN5NaO7P. Mole weight: 546.2. | |
| 8-Br-Xao | 8-Br-Xao, the intriguing research chemical, has gained traction in the biomedical industry for investigating its potential for treating cancer and inflammation. With promising results, it appears to be able to tamper with the activity of crucial enzymes and pathways involved in progressing diseases. Therefore, this compound holds intrigue as a potential drug for treating relevant conditions and is expected to involve further study and development. CAS No. 3001-46-6. Molecular formula: C10H11BrN4O6. Mole weight: 363.1. | |
| 8-BT-cAMP | 8-BT-cAMP is a selective activator of cAMP-dependent protein kinase. Compared to cAMP, it has superior stability and membrane permeability. Synonyms: 8- Benzylthioadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 50655-17-9. Molecular formula: C17H17N5O6PS · Na. Mole weight: 473.4. | |
| 8-CEA-Ado | 8-CEA-Ado is a reactive precursor for immobilisation. Synonyms: 8- Carboxyethylaminoadenosine. Grade: ≥ 97 % by HPLC. CAS No. 1161916-63-8. Molecular formula: C13H18N6O6. Mole weight: 364.3. | |
| 8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol | 8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Chloro-11-(1-methyl-4-piperidinyl)-11H-benzo[5,6]cyclohepta[1,2-b]-11-pyridinol. Grade: 98%. CAS No. 117811-17-3. Molecular formula: C20H21ClN2O. Mole weight: 340.85. | |
| 8-Chloro-11H-benzo[5,6]cyclo-hepta[1,2-b]pyridin-11-one | 8-chloro-11H-benzo[5,6]cyclo-hepta[1,2-b]pyridin-11-one is one of loratadine intermediates. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: Desloratadine Impurity 20; 13-Chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-one; Desloratadine Dehydro 11-Oxo Impurity; 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-. Grade: ≥95%. CAS No. 117811-16-2. Molecular formula: C14H8ClNO. Mole weight: 241.67. | |
| 8-Chloro-2'-beta-C-methylinosine | 8-Chloro-2'-beta-C-methylinosine, a remarkable compound in the biomedical industry, serves as a powerful antiviral agent. Its efficacy knows no bounds, effectively thwarting the replication of RNA viruses like Zika virus and Hepatitis C. By skillfully targeting viral RNA synthesis and translation, this compound proves its inhibitory potential. Grade: ≥95%. CAS No. 1106012-39-8. Molecular formula: C11H13ClN4O5. Mole weight: 316.70. | |
| 8-Chloro-2'-deoxy-2'-fluoroinosine | 8-Chloro-2'-deoxy-2'-fluoroinosine is a renowned pharmaceutical compound extensively utilized in the biomedical sector, showcasing profound antiviral attributes. Its dominant application pertains to studying the scourge of viral infections induced by the notorious herpes simplex virus, varicella-zoster virus and Epstein-Barr virus. Grade: ≥95%. Molecular formula: C10H10ClFN4O4. Mole weight: 304.66. | |
| 8-Chloro-2'-deoxyadenosine | 8-Chloro-2'-deoxyadenosine is an extensively researched synthetic compound, prominently finding application in studying chronic lymphocytic leukemia (CLL). Operating via its profound interference with the replication process, this remarkable compound exhibits inhibition in restraining the pernicious proliferation of cancerous cells. Synonyms: (2R,3S,5R)-5-(6-amino-8-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; Adenosine, 8-chloro-2'-deoxy-; 8-Chloro-2'-deoxy-D-adenosine; 8-Cl-d-Ado. Grade: ≥95%. CAS No. 85562-55-6. Molecular formula: C10H12ClN5O3. Mole weight: 285.69. | |
| 8-Chloro-2'-deoxyadenosine-5'-Triphosphate | 8-Chloro-2'-deoxyadenosine-5'-Triphosphate, an altered nucleoside triphosphate used in DNA synthesis and repair research, exhibits robust inhibition of DNA polymerase and is under investigation as a cancer treatment. In sequencing technology, 8-Chloro-2'-deoxyadenosine-5'-Triphosphate serves as a valuable probe. Synonyms: 8-Chloro-dATP. Grade: ≥90% by AX-HPLC. Molecular formula: C10H15N5O12P3Cl. Mole weight: 525.60. | |
| 8-Chloro-2'-deoxyguanosine | 8-Chloro-2'-deoxyguanosine is an extraordinary compound masterpiece, meticulously impeding the replication of the sacred DNA of tumor cells. Synonyms: 8-Chloro-2'-deoxy-D-guanosine. Grade: 98%. CAS No. 437715-62-3. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. | |
| 8-Chloro-2'-O-methylinosine | 8-Chloro-2'-O-methylinosine, an essential compound for the advancement of antiviral medications, plays a pivotal role in combating diverse viral infections including hepatitis C and respiratory syncytial virus (RSV). By impeding viral replication and leveraging its robust antiviral capabilities, this compound effectively aids in the management of these ailments. Grade: ≥95%. Molecular formula: C11H13ClN4O5. Mole weight: 316.70. | |
| 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 1-Oxide | 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one 1-Oxide is an intermediate for the preparation of Loratadine, which is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Uses: Intermediate for the preparation of loratadine impurities. Synonyms: 8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one N1-Oxide; 8-chloro-1-oxido-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-1-ium-11-one; 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-5,6-dihydro-, 1-oxide. Grade: ≥95%. CAS No. 133330-59-3. Molecular formula: C14H10ClNO2. Mole weight: 259.69. | |
| 8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol | 8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is one of loratadine impurities. Loratadine is a nonsedating-type histamine H1-receptor antagonist used to treat allergies. Synonyms: 8-Chloro-5,6-dihydro-11H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridin-11-ol; 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-6,11-dihydro-. CAS No. 133330-72-0. Molecular formula: C14H12ClNO. Mole weight: 245.71. | |
| 8-Chloroadenosine | 8-Chloroadenosine is an analog of adenosine. It is metabolized in vivo to 8-Chloro-ATP. It depletes ATP and inhibits tumor growth in hematological malignancies. It also inhibits tumor growth in lung and breast cancer cell lines. It incorporates into RNA during transcription and inhibits RNA synthesis. It mitotics catastrophe and induces G2/M cell cycle arrest in A549 and H1299 cells. It is a useful research chemical and has cytotoxicity effects. Synonyms: 6-Amino-8-chloropurine riboside; 8-Cl-Ado; 8-Chloro-adenosine; (2R,3R,4S,5R)-2-(6-amino-8-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-adenosine. Grade: ≥98% by HPLC. CAS No. 34408-14-5. Molecular formula: C10H12ClN5O4. Mole weight: 301.69. | |
| 8-Chloroadenosine 3',5'-Cyclic Monophosphate | 8-Chloroadenosine 3',5'-Cyclic Monophosphate is a cAMP analog with high selectivity for PKA I. Used in anti-cancer treatments. Uses: Antineoplastic agents. Synonyms: 8-Chloro-cAMP; 8-Chloro-cyclic AMP; 8-Chloroadenosine 3',5'-Cyclic Monophosphate; 8-Chloroadenosine 3',5'-Cyclic Phosphate; Adenazole; NSC 284751; NSC 614491; Tocladesine. Grade: 95%. CAS No. 41941-56-4. Molecular formula: C10H11ClN5O6P. Mole weight: 363.65. | |
| 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate | 8-Chloroadenosine 3',5'-cyclic monophosphate dihydrate is a key compound used in biomedical research. It acts as an adenosine receptor agonist, exhibiting therapeutic potential in the treatment of various diseases including cancer, inflammation, and neurodegenerative disorders. Its unique properties make it an essential tool for studying nucleotide signaling pathways and developing targeted therapies to combat these conditions. Molecular formula: C10H11ClN5O6P·2H2O. Mole weight: 399.69. | |
| 8-Chloro Anagrelide | 8-Chloro Anagrelide is an impurity of Anagrelide, a medication used for the treatment of thrombocythemia. Synonyms: Anagrelide trichloro derivative; 8-Chloroanagrelide. Grade: 95%. CAS No. 1092352-99-2. Molecular formula: C10H6Cl3N3O. Mole weight: 290.5. | |
| 8-Chloro Caffeine | 8-Chloro Caffeine is a halogenated analog of Caffeine, which is a central nervous system (CNS) stimulant used as a cognitive enhancer to increase alertness and attention performance. Synonyms: 8-Chloro-3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione; NSC 6277; EINECS 225-552-1; 1,3,7-Trimethyl-2,6-dioxo-8-chloro.1H,3H,7H-xanthine; 8-chloro-1,3,7-trimethylxanthine; 8-chloro-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione; Dimenhydrinate EP Impurity E. Grade: ≥95%. CAS No. 4921-49-7. Molecular formula: C8H9ClN4O2. Mole weight: 228.64. | |
| 8-Chloroguanosine | Burstiness and perplexity encapsulate two vital aspects of effective content writing. Introducing 8-Chloroguanosine, an invaluable chemical compound extensively utilized in the biomedical sector, aimed at investigating the intricate repercussions of oxidative stress-induced DNA impairment. Its eminent significance persists in the profound comprehension of DNA repair mechanisms and replication processes, primarily applicable in pioneering disease therapies, including cancer. Synonyms: 8-Cl-Guo; 2-Amino-8-chloro-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 8-chloro-; 8-Chloro-D-guanosine. Grade: ≥98% by HPLC. CAS No. 2104-68-9. Molecular formula: C10H12ClN6O6. Mole weight: 317.69. | |
| 8-Chloroinosine | A major metabolite of 8-Chloroadenosine. Synonyms: 8-Chloro-inosine; 8-Cl-I; (2R,3R,4S,5R)-2-(8-Chloro-6-hydroxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 8-Chloro-D-inosine; 9H-Purin-6-ol, 8-chloro-9-β-D-ribofuranosyl-. Grade: ≥95%. CAS No. 116285-77-9. Molecular formula: C10H11ClN4O5. Mole weight: 302.67. | |
| 8-Chloromethyl-6-nitro-4H-benzo[1,3]dioxine | 8-Chloromethyl-6-nitro-4H-benzo[1,3]dioxine is an antithrombotic PAI-1 inhibitor. Synonyms: 8-(chloromethyl)-6-nitro-2,4-dihydro-1,3-benzodioxine; 4H-1,3-Benzodioxin, 8-(chloromethyl)-6-nitro-; 8-(chloromethyl)-6-nitro-2H,4H-benzo[e]1,3-dioxane. Grade: ≥95%. CAS No. 99849-17-9. Molecular formula: C9H8ClNO4. Mole weight: 229.62. | |
| 8-Cl-2'-FDA-AEC-cAMP | 8-Cl-2'-FDA-AEC-cAMP is an extraordinary cyclic AMP analogue, emerging as an exquisite research tool within the biomedical sphere. Its versatile nature leads to unravelling the enigmatic cAMP-dependent signalling pathways and illuminating the intricate world of signal transduction. Synonyms: 8- Chloro- 2'- O- (fluoresceindiacetate- (2- aminoethylcarbamoyl))adenosine- 3', 5'- cyclic monophosphate. | |
| 8-Cl-5'-AMP | 8-Cl-5'-AMP is a potential metabolite of 8-chloroadenosine-3',5'-cyclic monophosphate. Synonyms: 8- Chloroadenosine- 5'- O- monophosphate, sodium salt. Grade: ≥ 97% by HPLC. CAS No. 37676-40-7. Molecular formula: C10H13ClN5O7P (free acid). Mole weight: 381.7 (free acid). | |
| 8-Cl-Ado | 8-Cl-Ado is a cytotoxic metabolite of 8-chloro cyclic AMP. Synonyms: 8- Chloroadenosine. Grade: ≥ 98% by HPLC. CAS No. 34408-14-6. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
| 8-Cl-ADP | 8-Cl-ADP is a metabolite of 8-Cl-cAMP and 8-Cl-adenosine and a precursor of 8-modified ADP derivatives. Synonyms: 8- Chloroadenosine- 5'- O- diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 185341-69-9. Molecular formula: C10H14ClN5O10P2 (free acid). Mole weight: 461.7 (free acid). | |
| 8-Cl-ATP | 8-Cl-ATP is a corresponding triphosphate form for research on 8-chloro cAMP and 8-Cl-adenosine. Synonyms: 8- Chloroadenosine- 5'- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 185341-71-3. Molecular formula: C10H15ClN5O13P3 (free acid). Mole weight: 541.6 (free acid). | |
| 8-Cl-cAMP | 8-Cl-cAMP is a selective cAMP analogue preferring protein kinase A type I. 8-Cl-cAMP has already been in several clinical trials to identify its inhibitory effect of growth and differentiation in cultured cancer cell lines. Synonyms: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 99% by HPLC. CAS No. 124705-03-9. Molecular formula: C10H10ClN5O6P · Na. Mole weight: 385.6. | |
| 8-Cl-cAMP-AM | 8-Cl-cAMP-AM is a precursor of 8-Cl-cAMP, the PKA activator. The polar active analogue is released after the metabolism of 8-Cl-cAMP-AM by esterases. Synonyms: 8- Chloroadenosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 97% by HPLC for mixture of isomers. Molecular formula: C13H15ClN5O8P. Mole weight: 435.7. | |
| 8-Cl-c-diAMP | 8-Cl-c-diAMP is an analogue of c-diAMP, the bacterial second messenger, which is used for binding studies and precursor for further modifications with spacers or labels. Synonyms: 8- Chloro- cyclic diadenosine monophosphate, sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H23ClN10O12P2 (free acid). Mole weight: 692.9 (free acid). | |
| 8-Cl-dAdo | 8-Cl-dAdo is a formidable and discriminating inhibitory compound, enthralling the enzyme ribonucleotide reductase. Synonyms: 8- Chloro- 2'- deoxyadenosine. Grade: ≥ 96% by HPLC. CAS No. 86662-66-6. Molecular formula: C10H12ClN6O3. Mole weight: 286.7. | |
| 8-Cl-dGuo | 8-Cl-dGuo, an anti-RNA virus crusader, is a nucleoside of robust antiviral power. Employed in treating life-threatening hepatitis C and coronavirus, it exercises the incredible ability of obstructing viral RNA replication. With a track record of reining in multiple viral strains, 8-Cl-dGuo, thanks to its singular structural features, is a forerunner in directing medicines to infected cells, shielding healthy tissues from toxicity. Synonyms: 8- Chloro- 2'- deoxyguanosine. Grade: ≥ 96% by HPLC. CAS No. 437716-62-3. Molecular formula: C10H12ClN6O4. Mole weight: 301.7. | |
| 8-Cl-Ino | 8-Cl-Ino is the potential metabolite of 8-chloro cyclic AMP and 8-chloroadenosine. Synonyms: 8- Chloroinosine. Grade: ≥ 98% by HPLC. CAS No. 116286-77-9. Molecular formula: C10H11ClN4O6. Mole weight: 302.7. | |
| 8-Cl-X | 8-Cl-X is a potential metabolite of 8-chloro cAMP. Synonyms: 8- Chloroxanthine. Grade: ≥ 95% by HPLC. CAS No. 13548-68-0. Molecular formula: C5H3ClN4O2. Mole weight: 186.6. | |
| 8-CPT-6-Phe-cAMP | 8-CPT-6-Phe-cAMP is a selective activator of protein kinase A (cAMP agonist). It effects against mammalian cyclic nucleotide-dependent phosphodiesterases. Grade: ≥ 98% by HPLC. CAS No. 72549-36-1. Molecular formula: C22H18ClN5O6PS·Na. Mole weight: 569.9. | |
| 8-CPT-cAMP | 8-CPT-cAMP is an activator of cAMP- and cGMP-dependent protein kinase and of Epac. It has an improved membrane permeability, phosphodiesterase stability and selectivity for site B of cAK type II. Uses: Enzyme inhibitors. Synonyms: 8- (4- Chlorophenylthio)adenosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 99% by HPLC. CAS No. 93882-12-3. Molecular formula: C16H14ClN5O6PS · Na. Mole weight: 493.8. | |
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