BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Urechistachykinin II | Urechistachykinin II (Uru-TK II)is an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, showing antimicrobial activities without a hemolytic effect. Synonyms: Uru-TK II; H-Ala-ala-gly-met-gly-phe-phe-gly-ala-arg-NH2. Grades: 95%. CAS No. 149097-04-1. Molecular formula: C44H66N14O10S. Mole weight: 983.15. |  |
| Urocortin III, mouse | Urocortin III a neuropeptide hormone and a member of the corticotropin-releasing factor (CRF) family, is a highly selective agonist of the CRF2 receptor and does not show affinity for the CRF binding protein. Synonyms: STRESSCOPIN (3-40) (MOUSE). CAS No. 357952-10-4. Molecular formula: C186H312N52O52S2. Mole weight: 4172.97. | |
| Ustilipid A | Ustilipid A is originally isolated from Ustilago maydie DSM 11494. It has the activity of antagonizing dopamine D1 and D2 receptors with the IC50 (μg/mL) of 30 and 5, respectively. Synonyms: [(2R,3S)-2,3,4-Trihydroxybutyl]2-O-hexanoyl-3-O-hexadecanoyl-4-O,6-O-diacetyl-beta-D-mannopyranoside. Molecular formula: C36H64O13. Mole weight: 704.88. | |
| Ustilipid B | Ustilipid B is originally isolated from Ustilago maydie DSM 11494. It has the activity of antagonizing dopamine D1 and D2 receptors with the IC50 (μg/mL) of 16 and 7, respectively. Molecular formula: C34H60O13. Mole weight: 676.83. | |
| Ustiloxin A | It is originally isolated from Ustilaginoidea virens. Ustiloxin A can inhibit the polymerization of tubulin with an IC50 of 0.7 μmol/L, and it also inhibits mitosis in various human tumor cell lines. Grades: ≥95%. CAS No. 143557-93-1. Molecular formula: C28H43N5O12S. Mole weight: 673.73. | |
| Ustiloxin B | It is originally isolated from Ustilaginoidea virens. Ustiloxin B can inhibit the polymerization of tubulin with an IC50 of 2.8 μmol/L, and it also inhibits mitosis in various human tumor cell lines. Grades: ≥98%. CAS No. 151841-41-7. Molecular formula: C26H39N5O12S. Mole weight: 645.68. | |
| Ustusol C | Ustusol C is produced by the strain of Aspergillus ustus. Synonyms: 6-O-methyl-12-hydroxy-6-epi-albrassitriol; 1,2-Naphthalenedimethanol, 1,4,4a,5,6,7,8,8a-octahydro-1-hydroxy-4-methoxy-5,5,8a-trimethyl-, (1S,4R,4aS,8aS)-. Grades: 98.0%. CAS No. 1188398-13-1. Molecular formula: C16H28O4. Mole weight: 284.39. | |
| Val-Ala-OH | Synonyms: L-Valyl-L-alanine; (S)-2-((S)-2-Amino-3-Methylbutanamido)Propanoic Acid; Val Ala OH. Grades: ≥ 98% (HPLC). CAS No. 27493-61-4. Molecular formula: C8H16N2O3. Mole weight: 188.23. | |
| Valanimycin | Valanimycin is produced by the strain of Str. viridifaciens MG456-hF10 (FERMP8146). It has anti-Gram-positive bacteria and negative bacteria action and the effect on anti-Gram-negative bacteria is stronger. In vitro, the IC50 of it on murine leukemia cell line L-1210 was 0.79 μg/mL. Synonyms: 2-[(2-methylpropyl)-ONN-azoxy]acrylic acid. CAS No. 101961-60-8. Molecular formula: C7H12N2O3. Mole weight: 172.18. | |
| Valerenic acid | Valerenic acid is a positive allosteric modulator of GABAA receptors displaying selectivity for receptors containing β2 or β3 subunits. Valerenic acid exhibits sedative, anticonvulsant and anxiolytic effects in vivo. Valerenic acid also acts as a partial agonist of 5-HT5A receptors. Synonyms: valerinic acid; (-)-valerenic acid. Grades: ≥99% by HPLC. CAS No. 3569-10-6. Molecular formula: C15H22O2. Mole weight: 234.33. | |
| Validamycin A | The major analogue of a family of cyclitol disaccharides isolated from streptomyces hygroscopicus var. Limoneus. It is a potent antifungal agent used to control fungi in crop production and acts as a potent inhibitor of trehalase, an important enzyme in carbohydrate storage and ultilisation in fungi. Synonyms: jinggangmycin; Antibiotic T 7545A. Grades: >95% by HPLC. CAS No. 37248-47-8. Molecular formula: C20H35NO13. Mole weight: 497.49. | |
| Validamycin B | Validamycin B is an impurity of Validamycin that is resistant to rice sheath blight disease and Pellicularia sasakii. Synonyms: Antibiotic T-7545-B; Val-B; (1R,2R,3S,4S,5R,6S)-2,3,5-trihydroxy-6-(hydroxymethyl)-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside; 1,5-Dideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol. CAS No. 102583-47-1. Molecular formula: C20H35NO14. Mole weight: 513.49. | |
| Validamycin C | An impurity of Validamycin. Validamycin is an antibiotic and fungicide. Synonyms: BRN 4835203; (3-{[4-(hexopyranosyloxy)-2,3-dihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-4,5,6-trihydroxycyclohex-1-en-1-yl)methyl hexopyranoside; 2-(hydroxymethyl)-6-[[3-[[5-(hydroxymethyl)-4-[6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,3-bis(oxidanyl)cyclohexyl]amino]-4,5,6-tris(oxidanyl)cyclohexen-1-yl]methoxy]oxane-3,4,5-triol. CAS No. 12650-70-3. Molecular formula: C26H45NO18. Mole weight: 659.63. | |
| Valinomycin | A hydrophobic cyclodepsipeptide with potent antitumour activity; a highly selective potassium ionophore; a biosensor to detect potassium efflux. Synonyms: Potassium ionophore I; valino; Valinomicin; NSC122023; Antibiotic N-329 B; cyclo[-D-O-Val-D-Val-L-O-Ala-L-Val]3; BRN 0078657; (3R, 6R, 9S, 12S, 15R, 18R, 21S, 24S, 27R, 30R, 33S, 36S)-3, 6, 9, 15, 18, 21, 27, 30, 33-Nonaisopropyl-12, 24, 36-trimethyl-1, 7, 13, 19, 25, 31-hexaoxa-4, 10, 16, 22, 28, 34-hexaazacyclohexatriacontane-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32,35-dodecone. Grades: >95% by HPLC. CAS No. 2001-95-8. Molecular formula: C54H90N6O18. Mole weight: 1111.32. | |
| Valnemulin | Valnemulin is a pleuromutilin antibiotic used to treat swine dysentery, ileitis, colitis and pneumonia. Synonyms: Econor; Biotilina. Grades: >99% by HPLC. CAS No. 101312-92-9. Molecular formula: C31H52N2O5S. Mole weight: 564.82. | |
| Valnemulin hydrochloride | The hydrochloride salt form of Valnemulin is a wide-spectrum antibiotic that has been found to have strong antibacterial activity especially against mycoplasma and spirochete, and is commonly used as a veterinary drug. It can prevent and control swine dysentery, ileitis, colitis and other intestinal diseases, as well as swine asthma and other respiratory diseases. Synonyms: Valnemulin HCl; UNII-W1GDP58BNQ; W1GDP58BNQ. Grades: >90%. CAS No. 133868-46-9. Molecular formula: C31H53ClN2O5S. Mole weight: 601.28. | |
| Val-Pro-OH HCl | Substrate for skin fibroblast prolidase. Synonyms: (S,S)-1-(2-Amino-3-methyl-butyryl)pyrrolidine-2-carboxylic acid hydrochloride; L-Valyl-L-proline hydrochloride; Val Pro OH HCl. Grades: ≥ 99% (TLC). CAS No. 105931-64-4. Molecular formula: C10H18N2O3HCl. Mole weight: 250.73. | |
| Val-Pro-Pro | Val-Pro-Pro is an angiotensin-converting enzyme inhibitor. Uses: Angiotensin-converting enzyme inhibitors. Synonyms: L-Valyl-L-prolyl-L-proline; L-Proline, 1-(1-L-valyl-L-prolyl)-. Grades: >98%. CAS No. 58872-39-2. Molecular formula: C15H25N3O4. Mole weight: 311.38. | |
| Vanoxonin | Vanoxonin is produced by the strain of Saccharopolyspora hirsuta. It can inhibit thymidylate synthase (IC50 = 0.7μg/mL). And the MIC of the complex against L-1210 and Ehrlich ascites cancer cells was 25 μg/mL. Synonyms: Antibiotic MG 245CF2A; N(sup 5)-Acetyl-N(sup 2)-(N-(2,3-dihydroxybenzoyl)-L-threonyl)-N(sup 5)-hydroxy-L-ornithine; (S)-2-((2S,3R)-2-(2,3-dihydroxybenzamido)-3-hydroxybutanamido)-5-(N-hydroxyacetamido)pentanoic acid. CAS No. 86933-99-5. Molecular formula: C18H25N3O9. Mole weight: 427.40. | |
| Variamycin | Variamycin is a glycoside antibiotic originally isolated from Streptomyces olivovariabilis 6604-9. It has the effect of resisting gram-positive bacteria, fungi and tumors. Synonyms: Variamitsin; Varamycin; NSC 269146; Antibiotic 6604-9A; 3(C)-Demethyl-4(C)-O-methylmithramycin. CAS No. 12677-11-1. Molecular formula: C52H76O24. Mole weight: 1085.14. | |
| Vasoactive intestinal polypeptide | Vasoactive intestinal polypeptide is a peptide hormone with vasoactive activity in the intestine, and has the functions of neuromodulator and neurotransmitter. Synonyms: H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-OH. CAS No. 37221-79-7. Molecular formula: C147H237N43O43S. Mole weight: 3326.8. | |
| VD-846 | VD-846 is an antibiotic produced by Streptomyces sp. with activity against gram-positive and -negative bacteria. Synonyms: Antibiotic VD 846 B; VD 846 B. CAS No. 21787-66-6. Molecular formula: C6H4N2O2S2. Mole weight: 200.2. | |
| Venturicidin A | The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A1. Grades: >95% by HPLC. CAS No. 33538-71-5. Molecular formula: C41H67NO11. Mole weight: 749.97. | |
| Venturicidin B | The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A2; (1R,2E,7R,8E,10R,12R,13S,17R)-7-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-17-hydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-2,10,12,20-tetramethyl-14,21-dioxabicyclo[15.3.1]henicosa-2,8,19-trien-15-one. Grades: >95% by HPLC. CAS No. 33538-72-6. Molecular formula: C40H66O10. Mole weight: 706.94. | |
| Veratridine | Veratridine, a pentacyclic triterpene acid compound, has been found to be a steroid-derived alkaloid neurotoxin and could be used as a voltage-gated Na+ channel opener. Synonyms: Veratrin (Amorphous); (3β,4α,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3-yl 3,4-dimethoxybenzoate. Grades: ≥90% by HPLC. CAS No. 71-62-5. Molecular formula: C36H51NO11. Mole weight: 673.79. | |
| Verdamycin | It is produced by the strain of Micromonospora grisea. Verdamycin has anti-bacterial effect. In in vivo test of mice, it has protective effect on the infection of Escherichia coli, Pseudomonas aeruginosa and Staphylococcus. Synonyms: Verdamicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6-)-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-threo-hept-4-enopyranosyl-(1-4))-2-deoxy-D-streptamine. Grades: 98%. CAS No. 49863-48-1. Molecular formula: C20H39N5O7. Mole weight: 461.55. | |
| Verlamelin | It is a depsipeptide antibiotic produced by the strain of Fungi MF 4683. It has anti-fungal activity against plant pathogens. Synonyms: MSD-A-43F; Verlamelin; A-43F; Antibiotic MSD-A-43F; Antibiotic A-43F; Cyclo[D-Tyr-5-L-Val-oxytetradecanoyl-D-aThr-D-Ala-L-Pro-L-Glu(NH2)-]. CAS No. 74758-64-8. Molecular formula: C45H71N7O11. Mole weight: 886.09. | |
| Vermiculine | Vermiculine is produced by the strain of Pen. vermiculatum CCM-F-2. It has anti-protozoal and anti-tumor effects, and it also has a less potent effect against gram-positive bacteria. Synonyms: Vermiculin; NSC657321; (-)-Vermiculine; 1,11-diene-2,5,10,13-tetrone,8,16-bis(2-oxopropyl)-, (3E,8S,11E,16S)-. CAS No. 37244-00-1. Molecular formula: C20H24O8. Mole weight: 392.40. | |
| Vermistatin | It is a new metabolite from mine-dwelling Penicillium vermiculatum. It is an antibiotic with cytotoxic effects. Synonyms: (R,E)-4,6-dimethoxy-3-(4-oxo-6-(prop-1-en-1-yl)-4H-pyran-3-yl)isobenzofuran-1(3H)-one; Fijiensin; (-)-Fijiensin; NSC 656107; 1(3H)-Isobenzofuranone, 4,6-dimethoxy-3-(4-oxo-6-(1-propenyl)-4H-pyran-3-yl)-, (R)-; 5-(4,6-Dimethoxy-3R-phthalidy)-2-(1E)-propenyl-4H-pyran-4-one. CAS No. 72669-21-7. Molecular formula: C18H16O6. Mole weight: 328.32. | |
| Vernamycin B | Vernamycin B is originally isolated from Str. loidensis. Vernamycin B has an antimicrobial effect, but is less effective against gram-negative bacteria and mycobacteria. CAS No. 9040-14-6. Molecular formula: C62H85N7O16S. Mole weight: 1216.44. | |
| Verrucarin A | It is produced by the strain of Myrothecium verrucaria NRRL 3003. Verrucarin A has the effect of anti-Gram-negative bacteria and fungi, inhibiting Newcastle disease virus, tobacco Mosaic virus, and S-37 sarcoma and Yoshida sarcoma in animals. Synonyms: Muconomycin A; Antibiotic 379Y; VER A; (4S, 5R, 10E, 12Z, 16R, 16aS, 17S, 18R, 19aR, 23aR)-4-hydroxy-5, 16a, 21-trimethyl-4, 5, 6, 7, 16, 16a, 22, 23-octahydro-3H, 18H, 19aH-spiro[16, 18-methano[1, 6, 12]trioxacyclooctadecino[3, 4-d]chromene-17, 2'-oxirane]-3, 9, 14-trione; NSC 126728. Grades: 95%. CAS No. 3148-9-2. Molecular formula: C27H34O9. Mole weight: 502.55. | |
| Verrucarin B | It is produced by the strain of Myrothecium verrucaria NRRL 3003. Verrucarin B has an effect on Ascites carcinoma, also has a weak inhibitory effect on fungi. Synonyms: (2'S,3'R)-2'-Deoxy-2',3'-oxyverrucarin A. CAS No. 2290-11-1. Molecular formula: C27H32O9. Mole weight: 500.54. | |
| Verrucarin J | Verrucarin J is produced by the strain of Myrothecium verrucaria NRRL 3003. The ED50 of Verrucarin J on giant cell tumor P-815 cells was about 0.001 μg/mL. Uses: For research used only. Synonyms: Muconomycin B; 2',3'-Didehydro-2'-deoxyverrucarin A; Verrucarin A, 2',?3'-didehydro-2'-deoxy-, (2'E)?-; Verrucrin J; Verrucosporin J. Grades: ≥98%. CAS No. 4643-58-7. Molecular formula: C27H32O8. Mole weight: 484.54. | |
| Verrucarin K | Verrucarin K is produced by the strain of Myrothecium verrucaria NRRL 3003. The ED50 of Verrucarin K on giant cell tumor P-815 cells was about 0.001 μg/mL. Synonyms: BRN 1276841; Verrucarin A, 12,13-deepoxy-12,13-didehydro-. CAS No. 63739-93-5. Molecular formula: C27H34O8. Mole weight: 486.55. | |
| Verrucofortine | A diketopiperazine alkaloid derived from tryptophan and leucine. It is a fungal metabolite isolated from penicillium verrucosum. It exhibits no apparent toxicity in mice even at high doses in vivo. Synonyms: Fructigenine B; Verrucosine; Verrucozine; (-)-Verrucofortine; (3S-(3alpha,5aalpha,10balpha,11abeta))-6-Acetyl-10b-(1,1-dimethyl-2-propenyl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-(3H,5aH)-dione; (3S,5aR,10bR,11aS)-6-acetyl-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grades: >99% by HPLC. CAS No. 113706-21-1. Molecular formula: C24H31N3O3. Mole weight: 409.52. | |
| Verruculogen | Verruculogen is a tremorgenic mycotoxin isolated from penicillium verruculosu. It can inhibit the K+ channel activated by ca2+, and is a cell cycle inhibitor that prevents M phase division. Synonyms: TR 1 toxin. Grades: >95% by HPLC. CAS No. 12771-72-1. Molecular formula: C27H33N3O7. Mole weight: 511.57. | |
| Versicolin | Versicolin is originally isolated from Asp. versicolor. It only has antibacterial effect on filamentous fungi, and has no inhibitory effect on yeast-like fungi and bacteria. Synonyms: 2,3,6-Trihydroxytoluene; Toluene-2,3,6-triol; BRN 2249549; 1-methyl-2,3,6-trihydroxybenzene. CAS No. 4389-44-0. Molecular formula: C7H8O3. Mole weight: 140.14. | |
| Versicolorin A | Versicolorin A is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Synonyms: Z-(-)-4,6,8-Trihydroxy-3a,12a-dihydroanthra(2,3-b)furo(3,2-d)furan-5,10-dione; NSC 274542; (3aS,12aR)-4,6,8-trihydroxy-3a,12a-dihydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione. Grades: 98%. CAS No. 6807-96-1. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Versicolorin B | Versicolorin B is a quinone antibiotic produced by the strain of Asp. versicolor. It has the effect of anti-tuberculosis Mycobacterium H37RV and other mycobacteria. Synonyms: (3aS,12aR)-4,6,8-trihydroxy-2,3,3a,12a-tetrahydroanthra[2,3-b]furo[3,2-d]furan-5,10-dione; Anthra(2,3-b)furo(3,2-d)furan-5,10-dione, 2,3,3a,12a-tetrahydro-4,6,8-trihydroxy-, cis-(+-)-. CAS No. 4331-22-0. Molecular formula: C18H12O7. Mole weight: 340.28. | |
| Vertimycin | It is a cyclopentane derivative of antibiotic produced by the strain of Streptoverticillium sp. JA 4498. It has anti-gram-positive bacteria and fungal effects. It has weak effect on Ehrlich ascites cancer cells in vitro. Synonyms: Cyclopentanone, 2-(2-hydroxyethoxy)-5-(hydroxymethyl)-; 1-Ethylenodiolo-3-methylolo-cyclopentanone-2; 1-(Aethylendiol-1,2)-methylol-3-cyclopentanon-2. CAS No. 14477-60-2. Molecular formula: C8H14O4. Mole weight: 174.19. | |
| Vertisporin | It is an antibiotic produced by the strain of Verticimonosporium diffractum TM-2098 and TM-2492. It has the effect against a few fungal. It is cytotoxic to HeLa cells with ED50 of 0.001 μg/mL. Synonyms: Spiro[4H-3a, 22-(epoxyethano)-10, 12-methano-17H, 18H-furo[2', 3':10, 11][1, 6]dioxacyclohexadecino[3, 4-d][1]benzopyran-11(12H), 2'-oxirane]-8, 20(5H, 22aH)-dione, 2, 3, 10, 10a, 13a, 16-hexahydro-2, 3-dihydroxy-10a, 15-dimethyl-, (2R, 2'S, 3R, 3aR, 6Z, 10R, 10aS, 12R, 13aR, 17aR, 21E, 21bR)-. CAS No. 57100-32-0. Molecular formula: C29H36O10. Mole weight: 544.59. | |
| Vibralactone B | Vibralactone B is an antibacterial compound produced from liquid fermentations of Stereum hirsutum that inhibits the growth of E. coli and Pseudomonas aeruginosa. Synonyms: (1beta)-2alpha-Prenyl-3beta-hydroxy-5beta-(hydroxymethyl)-6-oxabicyclo[3.1.0]hexane-2-carboxylic acid 2,3-lactone; 3,7-Dioxatricyclo[4.2.0.02,4]octan-8-one, 4-(hydroxymethyl)-1-(3-methyl-2-buten-1-yl)-, (1S,2R,4R,6S)-; (1S,2R*,3R*,5S)-2,3-epoxyvibralactone. Grades: ≥98%. CAS No. 1093230-95-5. Molecular formula: C12H16O4. Mole weight: 224.25. | |
| Vibralactone D | Vibralactone D is isolated from Boreostereum vibrans and exhibits weak inhibitory effect against isozymes of 11beta-hydroxysteroid dehydrogenases (HSD). Synonyms: (1S,5R,6S)-6-hydroxy-5-(3-methylbut-2-enyl)-3-oxabicyclo[3.2.1]octan-4-one; 3-Oxabicyclo[3.2.1]octan-2-one, 7-hydroxy-1-(3-methyl-2-buten-1-yl)-, (1R,5S,7S)-. Grades: ≥98%. CAS No. 1251748-32-9. Molecular formula: C12H18O3. Mole weight: 210.27. | |
| Vibralactone K | Vibralactone K is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Synonyms: 1H-Cyclopenta[c]furan-1-one, hexahydro-6-hydroxy-5-(3-methyl-2-buten-1-yl)-, (3aS,5S,6R,6aR)-. Grades: ≥98%. CAS No. 1623786-66-2. Molecular formula: C12H18O3. Mole weight: 210.27. | |
| Vibralactone L | Vibralactone L is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Synonyms: 3-Furanpropanoic acid, 2,5-dihydro-α-(3-methyl-2-buten-1-yl)-5-oxo-, ethyl ester, (+)-. Grades: ≥98%. CAS No. 1623786-67-3. Molecular formula: C14H20O4. Mole weight: 252.31. | |
| Vicenistatin | It is a macrocyclic lipid antibiotic produced by the strain of Str. sp. HC34. In vitro it is cytotoxic to human leukemia HL-60 cells and human colon cancer Co-LO205 cells with IC50 (μg/mL) of 0.12 and 0.19, respectively. Synonyms: Azacycloeicosa-3,5,10,13,15-pentaen-2-one, 7,11,13,19-tetramethyl-8-[[2,4,6-trideoxy-4-(methylamino)-β-D-ribo-hexopyranosyl]oxy]-, (3E,5E,7S,8S,10E,13E,15E,19S)-; Antibiotic HC34; NSC 641691; Vicenistatine. CAS No. 150999-05-6. Molecular formula: C30H48N2O4. Mole weight: 500.71. | |
| Victoxinine | Victoxinine is a toxic metabolite of Helminthosporium victoriae. Synonyms: (4aalpha,8aalpha)-Decahydro-8-methyl-9-methylene-5beta-isopropyl-4beta,8beta-methanoisoquinoline-2-Ethanol; Victoxinin; 4,8-Methanoisoquinoline-2(1H)-Ethanol, octahydro-8-methyl-9-methylene-5-(1-methylethyl)-, (4R,4aR,5R,8R,8aS)-rel-(+)-. Grades: ≥98%. CAS No. 39965-06-5. Molecular formula: C17H29NO. Mole weight: 263.42. | |
| Vinaxanthone | It is a semaphorin inhibitor produced by the strain of Penicillinm sp. SPF-3059. It inhibits Semaphorin with IC50 of 0.1 μg/mL. Synonyms: Antibiotic 411F; Antibiotic Ro-09-1450; 9H-Xanthene-1-carboxylic acid, 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxo-4H-1-benzopyran-3-yl)-2,3-dihydroxy-9-oxo-. CAS No. 133293-89-7. Molecular formula: C28H16O14. Mole weight: 576.42. | |
| Vinylamycin | It is a depsipeptide antibiotic produced by the strain of Streptomyces sp. M1982-63F1. It has activity against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 1.56-3.13 μg/mL. Synonyms: (8E,12S,15R)-3-(1-Methylheptyl)-4-(2-hydroxyethyl)-7-methylene-12-methyl-15-isopropyl-2-oxa-6,11,14-triazacyclopentadecane-8-ene-1,5,10,13-tetraone; 1-Oxa-4,7,12-triazacyclotetradec-9-ene-2,5,8,13-tetrone, 14-[1-(2-hydroxyethyl)-2-methyloctyl]-6-methyl-11-methylene-3-(1-methylethyl)-, (3R,6S,9E)-. CAS No. 224427-91-2. Molecular formula: C26H43N3O6. Mole weight: 493.64. | |
| Violacein | It is a nitrogenous heterocyclic indole antibiotic produced by the strain of Chromobacterium violaceum. It has anti-gram-positive bacteria, fungi and protozoa effects. The serum has an effect on its activity. Synonyms: (3E)-3-[5-(5-Hydroxy-1H-indol-3-yl)-2-oxo-1,2-dihydro-3H-pyrrol-3-yliden]-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 3-[1,2-dihydro-5-(5-hydroxy-1H-indol-3-yl)-2-oxo-3H-pyrrol-3-ylidene]-1,3-dihydro-, (3E)-. Grades: ≥ 95% (violacein and deoxyviolacein)?Violacein ≥ 80%. CAS No. 548-54-9. Molecular formula: C20H13N3O3. Mole weight: 343.34. | |
| Violaceol II | It is a mycotoxin isolated from Emericella violacea and Aspergillus spp. It has weak activity against Gram-positive bacteria, Gram-negative bacteria, fungi and yeast. Synonyms: violacerol-II; 3-(2,6-dihydroxy-4-methylphenoxy)-5-methylbenzene-1,2-diol; 5-methyl-2-[5-methyl-2,3-bis(oxidanyl)phenoxy]benzene-1,3-diol; 2-(2,3-dihydroxy-5-methyl-phenoxy)-5-methyl-resorcinol. CAS No. 81827-49-8. Molecular formula: C14H14O5. Mole weight: 262.26. | |
| Viomycin | Tuberactinomycin B is a member of the tuberactinomycin family of antibiotics used for the treatment of multidrug-resistant tuberculosis. Tuberactinomycin B inhibits group I intron splicing and prokaryotic protein synthesis, and freezes bacterial ribosomes in either the pre-or post-translational state. Uses: The treatment of multidrug-resistant tuberculosis. Synonyms: Tuberactinomycin B; Celiomycin; Florimycin; Viomicina; Viomycine; Viomycinum. CAS No. 32988-50-4. Molecular formula: C25H43N13O10. Mole weight: 685.69. | |
| Viomycin trihydrochloride | It is a peptide antibiotic produced by the strain of Str. puniceus 1314-5 and Str. floridae A5014. It has broad-spectrum antibacterial and strong anti-mycobacterium effect. 1-10 μg/mL of Viomycin can inhibit the growth of most tuberculosis bacilli, the main effect is to inhibit the protein synthesis of bacteria, but bacteria are prone to develop drug resistance. In clinical application, it is only used as a second-line drug to treat tuberculosis. Synonyms: Florimycin trihydrochloride; Viomycinum trihydrochloride; Vinacetin A trihydrochloride; Hexanamide, 3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[[(aminocarbonyl)amino]methylene]-3-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,1 3-pentaazacyclohexadec-15-yl]-, (3S)-, hydrochloride (1:3). CAS No. 39750-31-7. Molecular formula: C25H43N13O10.3HCl. Mole weight: 795.07. | |
| Vioxanthin | Vioxanthin is an antibiotic produced by Malbranchea pulchella var. sulfurea. It is active against gram-positive bacteria and bacteroides fragilis. Synonyms: Tf-26Vx. CAS No. 15447-05-9. Molecular formula: C30H26O10. Mole weight: 546.5. | |
| Viranamycin A | It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 5.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 6.4 ng/mL. Synonyms: Concanamycin A, 23-O-(3-carboxy-1-oxo-2-propenyl)-23-O-de[4-O-(aminocarbonyl)-2,6-dideoxy-b-D-arabino-hexopyranosyl]-25-de(1-propenyl)-25-methyl-. CAS No. 139595-03-2. Molecular formula: C41H64O13. Mole weight: 764.94. | |
| Viranamycin B | It is produced by the strain of Str. sp. CH 41. It can inhibit the growth of murine leukemia cell P388 with IC50 of 2.8 ng/mL, and it can also inhibit KB human multi-squamous cell carcinoma cells with IC50 of 1.9 ng/mL. Synonyms: Concanamycin A, 25-de(1-propenyl)-25-methyl-. CAS No. 139595-04-3. Molecular formula: C44H73NO14. Mole weight: 840.05. | |
| Virensic acid | It is a lichen acid with enzyme inhibitory potential. Synonyms: 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 4-formyl-3,8-dihydroxy-1,6,9-trimethyl-11-oxo-; 10-formyl-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylic acid; Granulatine; NSC 685587. CAS No. 668-14-4. Molecular formula: C18H14O8. Mole weight: 358.30. | |
| Virginiamycin S2 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin-S2; 4-L-Phenylalanine-5-(cis-4-hydroxy-L-2-piperidinecarboxylic acid)virginiamycin S1; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-L-Phe-[(4R)-4-hydroxy-L-pipecoloyl]-L-phenyl-Gly-]; N-[(3-Hydroxy-2-pyridyl)carbonyl]-cyclo[L-Thr*-D-Abu-L-Pro-L-Phe-4β-hydroxy-L-Hpr-L-phenyl-Gly-]. CAS No. 33477-38-2. Molecular formula: C42H49N7O10. Mole weight: 811.88. | |
| Virginiamycin S3 | It is a depsipeptide antibiotic produced by the strain of Str. virginiae and Str. virginiae var. sp. It has anti-gram-positive bacteria and mycobacterium effects, and the antibacterial activity of component M of Virginiamycin against cocci is stronger than component S, while the activity is stronger than component M. Synonyms: Staphylomycin S3; Virginiamycin S1, 5-(5-hydroxy-4-oxo-L-2-piperidinecarboxylic acid)-; N-[(3-Hydroxy-2-pyridinyl)carbonyl]cyclo[L-Thr*-D-Abu-L-Pro-N-methyl-L-Phe-4-oxo-5-hydroxy-L-pipecoloyl-L-phenyl-Gly-]. CAS No. 33477-39-3. Molecular formula: C43H49N7O11. Mole weight: 839.89. | |
| Viridicatin | It is a quinoline aromatic antibiotic produced by the strain of Pen. viridicatum, Pen. cyclopium SM-72 and Pen. puberulum. It has anti-gram-positive bacteria and mycobacteria effects. Synonyms: 2,3-dihydroxy-4-phenylquinoline; 2(1H)-Quinolinone, 3-hydroxy-4-phenyl-. Grades: >99% by HPLC. CAS No. 129-24-8. Molecular formula: C15H11NO2. Mole weight: 237.25. | |
| Viridicatol | Viridicatol is a fungal metabolite found in various Penicillium species as well as Phoma. It suppresses the expression of COX-2 and inducible nitric oxide synthase (iNOS) and inhibits production of nitric oxide and prostaglandin E2 (PGE2) in LPS-stimulated RAW 264.7 and BV2 cells. Synonyms: 2(1H)-Quinolinone, 3-hydroxy-4-(3-hydroxyphenyl)-; Carbostyril, 3-hydroxy-4-(m-hydroxyphenyl)-; 3-hydroxy-4-(3-hydroxyphenyl)carbostyril; 4-(3-Hydroxyphenyl)-2,3-quinolinediol. Grades: ≥95%. CAS No. 14484-44-7. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| Viridicatumtoxin | A tetracycline-like metabolite produced by several species of penicillium. It causes myocardial deterioration, renal tubule necrosis and spleen atrophy. It is a mycotoxin and a potent antibacterial with activity against S. Aureus including MRSA and QRSA strains. Synonyms: NSC 159628; viridicatumtoxin A; (1R,7'aR,11'aR,12'R)-rel-(-)-7',7'a,8',11',11'a,12'-hexahydro-5',6',7'a,10',11'a,12'-hexahydroxy-3'-methoxy-2,6,6-trimethyl-7',8'-dioxo-spiro[2-cyclohexene-1,2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide; (2'α, 7'aβ, 11'aβ, 12'β)-(-)-7', 7'a, 8', 11', 11'a, 12'-Hexahydro-5', 6', 7'a, 10', 11'a, 12'-hexahydroxy-3'-methoxy-2, 6, 6-trimethyl-7', 8'-dioxo-spiro[2-cyclohexene-1, 2'(1'H)-cyclopenta[de]naphthacene]-9'-carboxamide. Grades: >98% by HPLC. CAS No. 39277-41-3. Molecular formula: C30H31NO10. Mole weight: 565.57. | |
| Viridin | It is a steroidal antibiotic produced by the strain of Gliocladium virens. It has anti-fungal and gram-positive bacterial effects. Synonyms: (1S-(1alpha,2alpha,11balpha))-1,7,8,11b-Tetrahydro-1-hydroxy-2-methoxy-11b-methylcyclopenta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione; 18-Norandrosta-5,8,11,13-tetraeno(6,5,4-bc)furan-3,7,17-trione, 1-hydroxy-2-methoxy-, (1beta,2beta)-; Cyclopenta(7,8)phenanthro(10,1-bc)furan-3,6,9(2H)-trione, 1,7,8,11b-tetrahydro-1-hydroxy-2-methoxy-11b-methyl-, (1S,2R,11bS)-. CAS No. 3306-52-3. Molecular formula: C20H16O6. Mole weight: 352.34. | |
| Viridomycin F | It is a viridomycin antibiotic produced by the strain of Streptomyces sp. K96-0188. It has weak insecticidal and nematocidal activity. It also has weak activity against Piricularia oryzae and Acholeplasma laidlawii. Synonyms: Antibiotic K 96-0188. CAS No. 221394-79-2. Molecular formula: C21H14N3O9Fe. Mole weight: 508.20. | |
| Virustomycin A | Virustomycin A is a 18-membered macrolide antibiotic originally isolated from Streptomyces sp. AM-2604. It is effective against infectious and plant pathogenic fungi. It is active against trichomonads and various RNA and DNA viruses. Synonyms: AM 2604A; Antibiotic AM 2604A; [2R-[2R*[1S*[2R*, 4R*, 5S*, 6R*(E)], 2R*, 3S*], 3S*, 4E, 6E, 9R*, 10S*, 11S*, 12R*, 13R*, 14E, 16Z]]-2-[3-(11-Ethyl-10, 12-dihydroxy-3, 17-dimethoxy-7, 9, 13, 15-tetramethyl-18-oxooxacyclooctadeca-4, 6, 14, 16-tetraen-2-yl)-2-hydroxy-1-methylbutyl]tetrahydro-2-hydroxy-5-methyl-6-(1-propenyl)-2H-pyran-4-yl Ester 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-2-butenoic Acid; 23-O-De(4-O-aminocarbonyl-2,6-dideoxy-β-D-arabino-hexopyranosyl)-23-O-[4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-1,4-dioxo-2-butenyl]concanamycin A. Grades: ≥98%. CAS No. 84777-85-5. Molecular formula: C48H71NO14. Mole weight: 886.08. | |
| WA8242A | WA8242A is a PLA2 inhibitor consisting of A1 and A2. It is produced by Steptomyces violaceusniger No. 8242. Synonyms: WA-8242A. Molecular formula: C39H74N2O7. Mole weight: 683. | |
| WA8242B | WA8242B is a PLA2 inhibitor produced by Steptomyces violaceusniger No. 8242. Synonyms: WA-8242B. Molecular formula: C40H76N2O7. Mole weight: 697. | |
| Waol A | It is a trihydrofuran derivative with cytotoxicity produced by the strain of Myceliophthora lutea TF-0409. It has very weak anti-staphylococcus aureus activity. In cell culture, its cytoplasmic activity against HL 60, P388, T24, HeLa and A549 was 8-10 times weaker than adriamycin, but its cytoplasmic activity against HL 60/ADM was stronger than adriamycin (IC50 is 2.0 μg/mL). IC50 is 0.1 μg/mL. Synonyms: FD-211; NSC726144; NSC-726144; 5H-Furo[3,4-b]pyran-5-one, 2,3,7,7a-tetrahydro-3-hydroxy-2,7-di-(1E)-1-propen-1-yl-, (2R,3R,7S,7aR)-. Molecular formula: C13H16O4. Mole weight: 236.26. | |
| Waol B | It is a trihydrofuran derivative with cytotoxicity produced by the strain of Myceliophthora lutea TF-0409. It has very weak anti-staphylococcus aureus activity. In cell culture, its cytoplasmic activity against HL 60, P388, T24, HeLa and A549 was 8-10 times weaker than adriamycin, but its cytoplasmic activity against HL 60/ADM was stronger than adriamycin (IC50 is 2.0 μg/mL). IC50 is 0.2 μg/mL. Synonyms: FD-212; Propanoic acid, 3-[(2R,4S,5S)-dihydro-4-hydroxy-2,5-di-(1E)-1-propen-1-yl-3(2H)-furanylidene]-2-hydroxy-, methyl ester, (3E)-. Molecular formula: C14H20O5. Mole weight: 268.31. | |
| WAP-8294A II | WAP-8294A II is the main component of WAP-8294A, the anti-MRSA antibiotic isolated from the fermentation broth of Lysobacter sp. Synonyms: WAP-8294 A2. Molecular formula: C73H111N17O21. Mole weight: 1562.76. | |
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