BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Alfuzosin Impurity E HCl | An impurity of Alfuzosin. Synonyms: N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl]formamide hydrochloride. Grade: > 95%. CAS No. 1026411-59-5. Molecular formula: C15H21N5O3. HCl. Mole weight: 319.37 36.46. |  |
| a-L-Galactose-1-phosphate dipotassium salt | a-L-Galactose-1-phosphate dipotassium salt is a crucial compound playing a significant role in studying enzymes involved in the Leloir pathway, such as galactose-1-phosphate-uridyltransferase. This salt is employed in the research of potential drugs for studying galactosemia, a metabolic disorder caused by the deficiency of aforementioned enzymes. Synonyms: Dipotassium [(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] phosphate. Grade: ≥ 99%. CAS No. 262856-84-8. Molecular formula: C6H11K2O9P. Mole weight: 336.33. | |
| a-L-galactose-1-phosphate disodium salt | a-L-galactose-1-phosphate disodium salt, a highly significant compound in the realm of biomedicine, exhibits immense potential for therapeutic application in diverse metabolic disorders. It serves as a pivotal precursor for sphingolipid synthesis, thereby facilitating the effective management of afflictions such as Gaucher disease and Farber disease. Due to its indispensable involvement in enzymatic reactions, a-L-galactose-1-phosphate disodium salt harbors substantial promise for the forefront of novel drug advancement within the biomedical industry. Synonyms: β-L-Galactopyranose, 1-(dihydrogen phosphate)?, disodium salt. CAS No. 210100-25-7. Molecular formula: C6H11Na2O9P. Mole weight: 304.10. | |
| Algestone | A pregnane steroid, its acetonide is used as anti-inflammatory drug (topical) and combination with enanthate as injectable contraceptive. Uses: Progestins. Synonyms: (16α)-16,17-Dihydroxy-pregn-4-ene-3,20-dione; 16α,17-Dihydroxyprogesterone; 4-Pregnen-16α,17α-diol-3,20-dione; Alfasone; Alphasone. Grade: > 95%. CAS No. 595-77-7. Molecular formula: C21H30O4. Mole weight: 346.47. | |
| Algestone Acetonide | A steroidal progestin used as a contraceptive drug. Synonyms: 16alpha,17-Isopropylidendioxy-4-pregnen-3,20-dion; 16alpha,17-(Isopropylidenedioxy)pregn-4-ene-3,20-dione. Grade: > 95%. CAS No. 4968-9-6. Molecular formula: C24H34O4. Mole weight: 386.54. | |
| Algestone Acetophenide | Algestone Acetophenide is a progestational steroid that has been shown to increase the proteins in milk and serum in goats and decrease the weight gain of kids. Uses: Contraceptives, oral, synthetic. Synonyms: Alphasone Acetophenide; Deladroxone; Dihydroxyprogesterone Acetophenide; Droxone; Neolutin Depositum; 2H-Naphth[1',2':6,7]indeno[1,2-d][1,3]dioxole, Pregn-4-ene-3,20-dione derivative; [16α(R)]-16,17-[(1-Phenylethylidene)bis(oxy)]-pregn-4-ene-3,20-dione. Grade: > 95%. CAS No. 24356-94-3. Molecular formula: C29H36O4. Mole weight: 448.6. | |
| Alginic acid | In tablet and capsule formulations, alginic acid is used as a binder and disintegrating agent. Alginic acid is widely used as a thickener and suspension agent in various pastes, creams and gels. It is also used as a stabilizer for oil-in-water emulsions and as an antacid in therapy. Synonyms: Acidum alginicum; E400; Kelacid; L-gulo-D-mannoglycuronan; Polymannuronic acid; Protacid; Satialgine H8; Alginate 8; Alginate LV; Alginex; Kimica Acid; Laminal; Lamitex LV; Landalgine; Medisorb A; Norgine; OligoG; Rebasol; Satialgine; Snow acid algin G; Verdyol Super. CAS No. 9005-32-7. Molecular formula: (C6H8O6)n. | |
| Alibendol | Alibendol is an antispasmodic,choleretic, and cholekinetic. Synonyms: EB 1856; EB1856; EB-1856. Grade: >98%. CAS No. 26750-81-2. Molecular formula: C13H17NO4. Mole weight: 251.28. | |
| Aliconazole | An antifungal azole derivative. Synonyms: 1-[(Z)-2-(4-chlorophenyl)-3-(2,4-dichlorophenyl)prop-2-enyl]imidazole. CAS No. 63824-12-4. Molecular formula: C18H13Cl3N2. Mole weight: 363.67. | |
| Alifedrine hydrochloride | Alifedrine hydrochloride is a beta-adrenergic partial agonist and a positive inotropic agent, which moderately reduces the severity of ischaemia and reperfusion-induced ventricular arrhythmias. Synonyms: Alifedrine HCl. CAS No. 72913-80-5. Molecular formula: C18H27NO2.HCl. Mole weight: 325.9. | |
| Aligeron | Aligeron is a non-selective prostaglandin (PG) antagonist with vasodilatory properties. Synonyms: 1-(Diphenylmethyl)-4-(2-propenyl)piperazine; BRN 0543456. CAS No. 70713-45-0. Molecular formula: C20H24N2. Mole weight: 292.42. | |
| Alimemazine Hemitartrate Dimer Impurity | An impurity of Alimemazine (Trimetazidine), which is an antihistaminic compound and a phenothiazine derivative. Synonyms: Trimeprazine Hemitartrate Dimer Impurity; (2RS)-N,N,2-Trimethyl-3-(10H-3,10'-biphenothiazin phenothiazin-10-yl)propan-1-amine; (R)-3-(10H-[3,10'-biphenothiazin]-10-yl)-N,N,2-trimethylpropan-1-amine. Molecular formula: C30H29N3S2. Mole weight: 495.70. | |
| Alimemazine Impurity A | An impurity of Trimetazidine. Trimetazidine is a drug for angina pectoris. Synonyms: Trimeprazine Sulfoxide. Molecular formula: C18H22N2OS. Mole weight: 314.45. | |
| Alipamide | Alipamide is a bio-active chemical with a sequence-specific threading tetra-intercalator with an extremely slow dissociation rate constant. Uses: A bio-active chemical. Synonyms: Alipamide; Alipamidum; CI-546; CN 38474; CN-38,474; D-1721; D 1721; D1721; UNII-PE8925K9EY; 4-Chloro-N',N'-dimethyl-3-sulfamoylbenzohydrazide; Alipamid; CI 546; 2-chloro-5-(dimethylaminocarbamoyl)benzenesulfonamide. Grade: ≥98%. CAS No. 3184-59-6. Molecular formula: C9H12CLN3O3S. Mole weight: 277.03. | |
| Alirocumab | Alirocumab is a human monoclonal antibody that acts as a PCSK9 inhibitor. Alirocumab is indicated to reduce the risk of myocardial infarction, stroke, and unstable angina requiring hospitalization in adults with established cardiovascular disease. Synonyms: REGN-727; REGN 727; REGN727; SAR-236553; SAR 236553; SAR236553. Grade: 95%. CAS No. 1245916-14-6. Molecular formula: C6472H9996N1736O2032S42. Mole weight: 146.0 kDa. | |
| Alisertib | MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation. Synonyms: MLN8237; MLN-8237; MLN 8237; alisertib. Benzoic acid, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-. Grade: 0.98. CAS No. 1028486-01-2. Molecular formula: C27H20ClFN4O4. Mole weight: 518.9. | |
| Alisertib sodium | Alisertib sodium is a salt of Alisertib which is an inhibitor of Aurora A kinase with potential antineoplastic activity. Alisertib sodium induces apoptosis and autophagy through targeting the AKT/mTOR/AMPK/p38 pathway in leukemic cells. Synonyms: MLN 8237 sodium; Alisertib sodium anhydrous; Benzoic acid, 4-((9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido(5,4-d)(2)benzazepin-2-yl)amino)-2-methoxy-, sodium salt (1:1). CAS No. 1028486-06-7. Molecular formula: C27H19ClFN4NaO4. Mole weight: 540.90. | |
| Aliskiren | Aliskiren hemifumarate appears to bind to both the hydrophobic S1/S3-binding pocket and to a large, distinct subpocket that extends from the S3-binding site towards the hydrophobic core of renin. Oral bioavailability of Aliskiren hemifumarate is 2.4% in rats, 16% in marmosets and about 2.5% in humans. Aliskiren hemifumarate (< 10 mg/kg, oral) inhibits plasma renin activity and lowers blood pressure in sodium-depleted marmosets.Once-daily oral treatment with Aliskiren hemifumarate lowers blood pressure effectively, with a safety and tolerability profile, in patients with mild-to-moderate hypertension. Uses: Antihypertensive agent; renin; antagonists and inhibitors. Synonyms: CGP 60536; CGP60536B; Rasilez; SPP 100; Tekturna. Grade:>98%. CAS No. 173334-57-1. Molecular formula: C30H53N3O6. Mole weight: 551.76. | |
| Aliskiren Acid Impurity | An impurity of Aliskiren. Synonyms: Aliskiren Carboxylic Acid. Grade: > 95%. CAS No. 173400-13-0. Molecular formula: C30H52N2O7. Mole weight: 552.76. | |
| Aliskiren hemifumarate | Aliskiren is a direct renin inhibitor used for the treatment of essential hypertension. Synonyms: (αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeno-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-nonaoyl-2-methyl-propyl)-amide hemifumarate. Grade: 99%. CAS No. 173334-58-2. Molecular formula: C30H53N3O6·1/2C4H4O4. Mole weight: 1219.6. | |
| Aliskiren Hemifumarate (SSSRisomer) Impurity | An impurity of Aliskiren. Synonyms: (αS,γS,δS,ζR)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,ζ-bis(1-methylethyl)benzeneoctanamide (2E)-2-Butenedioate (2:1). Grade: > 95%. CAS No. 1630036-82-6. Molecular formula: C30H53N3O6.1/2(C4H4O4). Mole weight: 609.79. | |
| Alisporivir | Alisporivir, also known as DEB-025, a non-immunosuppressive cyclosporine A derivative, is acyclophil ininhibitor molecule with potent anti-hepatitis C virus (HCV) activity. Treatment with alisporivir alone or combined with PEGylated IFNalpha2a reduced the viral load in patients with chronic HCV infection. Synonyms: cyclo[Abu-N(Me)D-Ala-Xaa-Val-N(Me)Leu-Ala-D-Ala-N(Me)Leu-N(Me)Leu-N(Me)Val-N(Me)Bmt(E)]; (3S,6S,9S,12R,15S,18S,21S,24S,27R,30S,33S)-25,30-diethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,27,28-nonamethyl-6,9,18-tris(2-methylpropyl)-3,21,24-tri(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone; alisporivir; DEBIO-025; MeAla(3)EtVal(4)-cyclosporin; UNIL 025; UNIL-025; UNIL025. Grade: 98.15%. CAS No. 254435-95-5. Molecular formula: C63H113N11O12. Mole weight: 1216.64. | |
| Alizapride | Alizapride is a dopamine antagonist. It has prokinetic and antiemetic effects and is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides. It has been listed. Uses: Alizapride has prokinetic and antiemetic effects and is used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Synonyms: N-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide; 1H-benzotriazole-5-carboxamide,6-methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)met; 6-Methoxy-n-((1-(2-propenyl)-2-pyrrolidinyl)methyl)-1h-benzotriazole-5-carbo; 6-Methoxy-N-{[1-(2-propny. Grade: 98%. CAS No. 59338-93-1. Molecular formula: C16H21N5O2. Mole weight: 315.37. | |
| Alizapride hydrochloride | Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Synonyms: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Hydrochloride; Limican; Nausilen; Plitican; Vergentan; N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1). Grade: >98%. CAS No. 59338-87-3. Molecular formula: C16H22ClN5O2. Mole weight: 351.83. | |
| ALK2-IN-4 | ALK2-IN-4 is a potent ALK2 inhibitor. Synonyms: ALK2-IN-4; 2248154-85-8; 8DLP7XK3VH; KER047; KER-047; UNII-8DLP7XK3VH; Quinoline, 7-fluoro-6-methoxy-4-(6-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)pyrazolo(1,5-a)pyrimidin-3-yl)-; SCHEMBL22027704; BDBM603696; EX-A4395; US11654147, Compound 15; US11654147, Compound 45; US11654147, Compound 346; US11654147, Compound 351; AKOS040757480; MS-28824; HY-136773; CS-0133581; 7-fluoro-6-methoxy-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline. Grade: 98%. CAS No. 2248154-85-8. Molecular formula: C26H30FN7O. Mole weight: 475.56. | |
| ALK2-IN-4 succinate | ALK2-IN-4 succinate is a potent ALK2 inhibitor. Synonyms: ALK2-IN-4 (succinate). Grade: 98%. CAS No. 2416307-25-8. Molecular formula: C30H36FN7O5. Mole weight: 593.65. | |
| ALK4290 | ALK4290 is a potent and orally active CCR3 inhibitor with a Ki value of 3.2 nM for hCCR3. ALK4290 is used to study neovascular age-related macular degeneration and Parkinson's disease. (Extracted from patent US20130261153A1, compound Example 2). Synonyms: AKST4290; Lazucirnon; 2-({1-[1-(4-Chloro-3-methylbenzyl)-4-piperidinyl]-5-oxo-D-prolyl}amino)-N,N,6-trimethylisonicotinamide; 4-Pyridinecarboxamide, 2-[[[(2R)-1-[1-[(4-chloro-3-methylphenyl)methyl]-4-piperidinyl]-5-oxo-2-pyrrolidinyl]carbonyl]amino]-N,N,6-trimethyl-; ALK-4290. Grade: ≥95%. CAS No. 1251528-23-0. Molecular formula: C27H34ClN5O3. Mole weight: 512.04. | |
| ALK5 Inhibitor II hydrochloride | ALK5 inhibitor II was identified as a cell permeable, selective inhibitor of the TGF-β type 1 activin like kinase receptor ALK5 (ALK5 autophosphorylation, IC50s = 4 nM, TGF-β cellular assay, IC50s = 18 nM, ALK5 binding in HepG2 cells, IC50s = 23 nM). This compound has been used to induce stem cell pluripotency by replacing the reprogramming transcription factor Sox2 via inhibition of the TGF-β signaling pathway and induction of Nanog transcription. This product is a hydrochloride form. Synonyms: E 616452; RepSox; SJN 2511. Grade: ≥98%. CAS No. 446859-33-2. Molecular formula: C17H13N5·HCl. Mole weight: 323.8. | |
| ALK-IN-12 | ALK-IN-12 is a potent and orally active ALK inhibitor with an IC50 of 0.18 nM. It also inhibits IGF1R and InsR (IC50 = 20.3 and 90.6 nM). Synonyms: ALK-IN-12; CHEMBL3822611; 1197958-53-4; SCHEMBL11916443; BCP25205; BDBM50185280; AKOS040756539; HY-108230; CS-0027595; 5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]-2,4-pyrimidinediamine. CAS No. 1197958-53-4. Molecular formula: C24H30ClN6O2P. Mole weight: 500.96. | |
| ALK-IN-13 | ALK-IN-13 is an ALK inhibitor. Synonyms: 2,4-Pyrimidinediamine, 5-chloro-N4-[4-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-. CAS No. 1197953-88-0. Molecular formula: C29H39ClN7O2P. Mole weight: 584.09. | |
| ALK-IN-5 | ALK-IN-5 is a potent, selective, and brain-penetrant inhibitor of anaplastic lymphoma kinase (ALK, IC50 = 2.9 nM). CAS No. 2351929-66-1. Molecular formula: C24H25FN6O3. Mole weight: 464.49. | |
| ALK-IN-9 | ALK-IN-9 is a potent ALK inhibitor. ALK-IN-9 inhibits cell proliferation with IC50s of <0.2 nM, <0.2 nM, 0.2 nM for Ba/F3-EML4-ALK, KM 12 (TPM3-TRKA), KG-l cell (OP2-FGFR1), respectively. CAS No. 2359662-39-6. Molecular formula: C20H21FN6O3. Mole weight: 412.42. | |
| ALK inhibitor 1 | ALK inhibitor 1 is a novel and selective inhibitor for the ALK kinase. Synonyms: Benzenesulfonamide, 2-[[5-bromo-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grade: >98%. CAS No. 761436-81-1. Molecular formula: C23H28BrN7O3S. Mole weight: 562.48. | |
| ALK inhibitor 2 | ALK inhibitor 2 is a novel and selective inhibitor for the ALK kinase. Synonyms: Benzenesulfonamide, 2-[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grade: >98%. CAS No. 761438-38-4. Molecular formula: C23H28ClN7O3S. Mole weight: 518.03. | |
| ALK/ROS1-IN-1 | ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor, with IC50s of 0.174 μM and 0.530 μM for ALK and ROS1 enzyme, respectively. CAS No. 2365497-07-8. Molecular formula: C30H35F3N6O3. Mole weight: 584.63. | |
| Alkylsophorolipids | Alkylsophorolipids, custom-synthesized complex carbohydrates, consist of oligosaccharides and methylated sugars that are fluorinated at the C3 position. This modification increases the molecule's hydrophobicity, making it more soluble in organic solvents such as chloroform. | |
| Alkyne-Modifier dT CE Phosphoramidite | Alkyne-Modifier dT CE Phosphoramidite is a modified nucleotide reagent designed for solid-phase oligonucleotide synthesis, enabling site-specific incorporation of an alkyne functional group into DNA or RNA strands. This alkyne moiety serves as a versatile chemical handle for post-synthetic conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) ''click'' chemistry, allowing attachment of diverse azide-functionalized molecules such as fluorophores, quenchers, biotin, or other labels. The reagent is compatible with standard synthesis and deprotection protocols, and its alkyne modification minimally disrupts oligonucleotide structure, making it ideal for applications like dual-labeled hydrolysis probes (e.g., TaqMan probes), molecular beacons, and therapeutic oligonucleotides requiring precise functionalization. Synonyms: Alkyne-Modifier dT Phosphoramidite. Grade: ≥95%. Molecular formula: C54H69N6O11P. Mole weight: 1009.15. | |
| Alkyne-Modifier Serinol Phosphoramidite | Alkyne-Modifier Serinol Phosphoramidite is a potent chemical reagent that pervasively aids in the synthesis of oligonucleotides for biomedical research purposes. Its proficiency lies in the assortment, stability, solubility enhancement and augmented bioavailability of DNA and RNA modification. Not only that, it proficiently gets the job done in developing gene therapies with targeted drug delivery systems for treating ailments like cancer, viral infections, and genetic disorders. Synonyms: 3-Dimethoxytrityloxy-2-(3-(5-hexynamido)propanamido)propyl-1-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 3-[bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl ester; 3-[Bis(4-methoxyphenyl)phenylmethoxy]-2-[[1-oxo-3-[(1-oxo-5-hexyn-1-yl)amino]propyl]amino]propyl 2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite. Grade: 95%. CAS No. 2084118-98-7. Molecular formula: C42H55N4O7P. Mole weight: 758.88. | |
| Alkyne-NHS Ester | Alkyne-NHS Ester, a vital chemical compound, is increasingly employed in bioconjugation reactions to append alkyne groups to proteins, peptides, or other molecules. This action enables the detection or labeling of biomolecules with a plethora of techniques, including fluorescent microscopy or mass spectrometry. Alkyne-NHS Ester is particularly valuable in drug discovery and development research as well as diagnostic applications for infectious diseases, thereby reinforcing its significance in the world of science. Synonyms: 3-propargyloxypropanoic acid N-hydroxysuccinimidyl ester. Molecular formula: C10H11NO5. Mole weight: 225.20. | |
| Alkynyl-modifier-C6-dT CEP | Alkynyl-modifier-C6-dT CEP is a renowned compound extensively utilized in the biomedical sector, serving as a pivotal chemical modification compound employed for labeling and detection purposes across diverse applications in compound research and disease analysis. Molecular formula: C48H58N5O9P. Mole weight: 879.98. | |
| Allantoxanamide | Allantoxanamide was reported to be a novel inhibitor of uricase in vivo. Synonyms: 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxamide; 4,6-dioxo-1H-1,3,5-triazine-2-carboxamide; 4-Hydroxy-6-oxo-1,6-dihydro-1,3,5-triazine-2-carboxamide. Grade: 95%. CAS No. 69391-08-8. Molecular formula: C4H4N4O3. Mole weight: 156.1. | |
| Allatostatin IV TFA | Allatostatin IV TFA is a pleiotropic neuropeptide that inhibits the synthesis of juvenile hormones in insects. Molecular formula: C47H69F3N12O14. Mole weight: 1083.13. | |
| all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester | all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester is an omega-3 fatty acid agent. It is important polyunsaturated fatty acid of the marine food chain. It serves as a precursor of the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid by the extra double bond between the third and fourth carbons from the "methyl end" of the molecule. It reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase A2, apolipoprotein B, very low-density lipoprotein cholesterol, and total cholesterol. It reduces the TG levels and improved other lipid parameters without significantly increasing the LDL cholesterol levels. It is used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. It has anti-inflammatory and cardiovascular benefits. It may alter the expression of genes related to fatty acid metabolism. It was the second class of fish oil-based drug to be approved for use as a drug. It was developed by Amarin Corporation. It has been listed. Uses: All cis-5,8,11,14,17-eicosapentaenoic acid ethyl ester reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase a2, apolipoprotein b, very low-density lipoprotein cholesterol, and total cholesterol. it has anti-inflammatory and cardiovascular benefits. Synonyms: Eicosapentaenoic Acid Ethyl Ester; (5Z, | |
| Allethrin | Allethrin is a synthetic pyrethroid derivative used as an insecticide. Allethrin induces oxidative stress, apoptosis and calcium release in rat testicular carcinoma cells (LC540). Allethrin induces BCL-2, caspase-3 activation and release of intracellular calcium. Synonyms: Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl ester (ACI). CAS No. 584-79-2. Molecular formula: C19H26O3. Mole weight: 302.41. | |
| Allisartan isoproxil | Allisartan isoproxil is a nonpeptide angiotensin II receptor blocker (ARB) precursor drug that is used to treat hypertension and reduce the risk of heart disease. Allisartan isoproxil alleviates diabetic cardiomyopathy by attenuating diabetes - induced oxidative stress and inflammation through the SIRT1/Nrf2/NF - κB signalling pathway. Synonyms: 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, (((1-methylethoxy)carbonyl)oxy)methyl ester; SB16810; SB-16810; SB 16810. CAS No. 947331-05-7. Molecular formula: C27H29ClN6O5. Mole weight: 553.02. | |
| ALLO-1 | ALLO-1 is a SMO antagonist that inhibits both wild-type (IC50 = 50 nM) and mutant SMO, including the D473H SMO mutant (IC50s = 300-1000 nM). ALLO-1 is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif. This compound binds to the SMO cysteine-rich domain, which is a different mechanism of interaction compared to other known SMO ligands that bind the transmembrane pocket. Synonyms: 3-(4-Chlorophenyl)-5-methyl-1-(phenylmethyl)-2,4-imidazolidinedione. Grade: ≥98%. CAS No. 37468-32-9. Molecular formula: C17H15ClN2O2. Mole weight: 314.8. | |
| Allo-3a-tetrahydro cortisol 21-O-b-D-glucuronide | Allo-3a-tetrahydro cortisol 21-O-b-D-glucuronide is a vital compound used in the biomedical industry commonly employed for studying the metabolism and excretion of cortisol, a hormone involved in stress response. This compound aids in investigations related to cortisol's glucuronidation process, providing insights into the research of various disorders, such as Cushing's syndrome or adrenal insufficiency. Synonyms: (3a,5a,11b)-3,11,17-Trihydroxy-20-oxopregnan-21-yl b-D-glucopyranosiduronic acid; allo-tetrahydrocortisol 21-glucuronide. CAS No. 131061-62-6. Molecular formula: C27H42O11. Mole weight: 542.62. | |
| Allo-3a-tetrahydro cortisol 3-O-b-D-glucuronide | Allo-3a-tetrahydro cortisol 3-O-b-D-glucuronide is a highly intricate and sophisticated compound that is widely employed in the in-depth investigations pertaining to the metabolism. Its paramount significance lies in its pivotal role in the exploration of adrenal function and the precise quantification of cortisol. Synonyms: (3a,5a,11b)-11,17,21-trihydroxy-20-oxopregnan-3-yl b-D-glucopyranosiduronic acid; 5a-Tetrahydrocortisol-3-monoglucuronide; Allotetrahydrocortisol 3-glucuronide. CAS No. 30954-21-3. Molecular formula: C27H42O11. Mole weight: 542.62. | |
| allo-Inositol | Allo-Inositol is a naturally occurring compound, exhibiting innate importance in conducting intricate cellular signaling and metabolic processes. Its profound presence within the biomedical industry remains notable due to its pivotal role in research of a myriad of ailments, including diabetes, polycystic ovary syndrome (PCOS) and neurodegenerative disorders. Synonyms: myo-inositol; Scyllo-inositol. Grade: >98.0%(LC). CAS No. 643-10-7. Molecular formula: C6H12O6. Mole weight: 180.16. | |
| Allopurinol EP Impurity A | 3-Amino-4-pyrazolecarboxamide hemisulfate salt is an impurity of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: 3-Amino-4-pyrazolecarboxamide hemisulfate; 1H-Pyrazole-4-carboxamide, 3-amino-, sulfate (2:1); 3-Amino-1H-pyrazole-4-carboxamide Hemisulfate; 5-Aminopyrazole-4-carboxamide hemisulphate. Grade: 98 %. CAS No. 27511-79-1. Molecular formula: C8H14N8O6S. Mole weight: 350.32. | |
| Allopurinol Impurity A | A metabolite of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: 3-Amino-1H-pyrazole-4-carboxamide. Grade: > 95%. CAS No. 5334-31-6. Molecular formula: C4H6N4O. Mole weight: 126.12. | |
| Allopurinol Impurity B | A metabolite of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: 3-(Formylamino)-1H-pyrazole-4-carboxamide. Grade: > 95%. CAS No. 22407-20-1. Molecular formula: C5H6N4O2. Mole weight: 154.13. | |
| Allopurinol Impurity C | A metabolite of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: Allopurinol Related Compound C; 3-(4H-1,2,4-Triazol-4-yl)-1H-pyrazole-4-carboxamide. Grade: > 95%. CAS No. 1346604-13-4. Molecular formula: C6H6N6O. Mole weight: 178.15. | |
| Allopurinol Impurity D | A metabolite of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: 3-Amino-4-carbethoxypyrazole; Ethyl 3-amino-4-pyrazolecarboxylate; Allopurinol Related Compound D; Allopurinol EP Impurity D; Allopurinol USP Related Compound D; 5-Amino-1H-pyrazole-4-carboxylic acid ethyl ester; Ethyl 3-aminopyrazole-4-carboxylate. Grade: > 95 %. CAS No. 6994-25-8. Molecular formula: C6H9N3O2. Mole weight: 155.16. | |
| Allopurinol Impurity E | A metabolite of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 31055-19-3. Molecular formula: C7H9N3O3. Mole weight: 183.17. | |
| Allopurinol Impurity F | A metabolite of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: (E/Z)-3-[(2-Cyano-3-ethoxy-3-oxo-1-propenyl)amino]-1H-Pyrazole-4-carboxylic Acid Ethyl Ester. Grade: > 95%. CAS No. 321571-07-7. Molecular formula: C12H14N4O4. Mole weight: 278.27. | |
| Allopurinol Nitrile Impurity | Allopurinol Nitrile Impurity is an impurity of Allopurinol, a xanthine oxidase inhibitor used to treat gout. Synonyms: 3-Amino-4-pyrazolecarbonitrile; 3-Amino-1H-pyrazole-4-carbonitrile; 1H-Pyrazole-4-carbonitrile, 3-amino-; 5-Aminopyrazole-4-carbonitrile. Grade: 95 %. CAS No. 16617-46-2. Molecular formula: C4H4N4. Mole weight: 108.10. | |
| Allopurinol riboside | Allopurinol riboside is a noteworthy compound, astutely used in research of kidney stones and hyperuricemia, wielding its powers as a potent xanthine oxidase inhibitor. By hindering uric acid compoundion, it proficiently mitigates the jeopardy of crystal deposition. Uses: Antiprotozoal agents. Synonyms: Allopurinol riboside; 16220-07-8; Allopurinol ribonucleoside; Allopurinol-1-ribonucleoside; WZS8452SEC; 4-Hydroxy[3,4-d]pyrazolopyrimidine riboside; CHEMBL1688966; CHEBI:74074; 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5-dihydro-1-beta-D-ribofuranosyl-; 4-Hydroxy(3,4-d)pyrazolopyrimidine riboside; 1-[(2R,3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE; 1-beta-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4-one; 4H-Pyrazolo(3,4-d)pyrimidin-4-one, 1,5-dihydro-1-.beta.-D-ribofuranosyl-1111. Grade: ≥ 97%. CAS No. 16220-07-8. Molecular formula: C10H12N4O5. Mole weight: 268.23. | |
| Allopurinol Sodium | Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM. Synonyms: Sodium allopurinol; Allopurinol sodium salt; NSC 108836; 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one,monosodiumsalt. Grade: >98%. CAS No. 17795-21-0. Molecular formula: C5H3N4NaO. Mole weight: 158.09. | |
| Allotetrahydrocortisol | Allotetrahydrocortisol is a metabolite of Cortisol, which is a glucocorticoid secreted by the adrenal cortex used to treat immune, inflammatory, and neoplastic conditions. Synonyms: Pregnan-20-one, 3,11,17,21-tetrahydroxy-, (3α,5α,11β)-; (3α,5α,11β)-3,11,17,21-Tetrahydroxypregnan-20-one; 5α-Pregnan-20-one, 3α,11β,17,21-tetrahydroxy-; 3α,11β,17,21-Tetrahydroxy-5α-pregnan-20-one; 3α,11β,17α,21-Tetrahydroxy-5α-pregnan-20-one; 3α,5α-Tetrahydrocortisol; 5α-Pregnane-3α,11β,17α,21-tetraol-20-one; 5α-Pregnane-3α,11β,17α,21-tetrol-20-one; 5α-Tetrahydrocortisol; 5α-THF; AL 3308; Allo-3α-tetrahydrocortisol; allo-Tetrahydrocortisol; Allopregnane-3α,11β,17α,21-tetrol-20-one; Allotetrahydrocompound F; ATHF; Cortisol, allotetrahydro-; Kendall's compound C; NSC 86469; Reichstein's substance C; Wintersteiner's compound D; α-THF. Grade: ≥95%. CAS No. 302-91-0. Molecular formula: C21H34O5. Mole weight: 366.49. | |
| Allo-UDCA | Allo-UDCA is an impurity of ursodeoxycholic acid (UDCA), a naturally occurring hydrophilic bile acid. Synonyms: 3alpha,7beta-Dihydroxy-5alpha-cholan-24-oic Acid; Ursodesoxycholsaure; Alloursodeoxycholic acid. CAS No. 105227-28-9. Molecular formula: C24H40O4. Mole weight: 392.57. | |
| Alloxazine | Alloxazine is a selective adenosine A2B-R (A2B adenosine receptor) antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor. Synonyms: Benzo[g]pteridine-2,4(1H,3H)-dione; 10H-Benzo[g]pteridine-2,4-dione; 1H,2H,3H,4H-Benzo[g]pteridine-2,4-dione; 2,4-Dioxobenzo[g]pteridine; 6,7-Benzolumazine; Benzo[g]pteridine-2,4(3H,10H)-dione; Flavoquinone; Isoalloxazine; NSC 203056; NSC 402746. Grade: ≥95%. CAS No. 490-59-5. Molecular formula: C10H6N4O2. Mole weight: 214.18. | |
| All-rac-alfa-Tocopherol EP Impurity A | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. Molecular formula: C29H50O2. Mole weight: 430.72. | |
| All-rac-alfa-Tocopherol EP Impurity A (Mixture of Diastereomers) | An intermediate in the synthesis of (all-rac)-α-Tocopherol and an impurity of Vitamin E. Uses: An intermediate in the synthesis of (all-rac)-α-tocopherol. Synonyms: 2,3-DIHYDRO-2,3,4,6,7-PENTAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-5-BENZOFURANOL; 2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol. Grade: 95%. CAS No. 185672-33-7. Molecular formula: C29H50O2. Mole weight: 430.70. | |
| All-rac-alfa-Tocopherol EP Impurity B | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. Molecular formula: C29H50O2. Mole weight: 430.72. | |
| All-rac-alfa-Tocopherol EP Impurity C | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. Synonyms: (E)-4-methoxy-2,3,6-trimethyl-5-(3,7,11,15-tetramethylhexadec-2-en-1-yl)phenol. CAS No. 90510-39-7. Molecular formula: C30H52O2. Mole weight: 444.73. | |
| all-rac-cis-2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol | All-rac-cis-2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol is an impurity of Tocopherol. Synonyms: (2R,3R)-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-3H-1-benzofuran-5-ol; All-rac-alfa-Tocopherol EP Impurity B; (2R,3R)-2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydro-1-benzofuran-5-ol; 5-Benzofuranol, 2,3-dihydro-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-, (2R,3R)-. Molecular formula: C29H50O2. Mole weight: 430.70. | |
| all-rac-trans-2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol | All-rac-trans-2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydrobenzofuran-5-ol is an impurity of Tocopherol. Synonyms: (2R,3S)-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-3H-1-benzofuran-5-ol; All-rac-alfa-Tocopherol EP Impurity A; (2R,3S)-2,3,4,6,7-Pentamethyl-2-(4,8,12-trimethyltridecyl)-2,3-dihydro-1-benzofuran-5-ol; 5-Benzofuranol, 2,3-dihydro-2,3,4,6,7-pentamethyl-2-(4,8,12-trimethyltridecyl)-, (2R,3S)-. Molecular formula: C29H50O2. Mole weight: 430.70. | |
| all-trans-18-Hydroxy Retinoic Acid | all-trans-18-Hydroxy Retinoic Acid is a hydroxylated metabolite of all-trans-Retinoic Acid. Synonyms: 18-Hydroxy-all-trans-retinoic acid; 18-Hydroxyretinoic acid; Ro 12-4825; 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(6,6-dimethyl-2-(hydroxymethyl)-1-cyclohexen-1-yl)-, (E)-; all-trans-9-(2-(Hydroxymethyl)-6,6-dimethyl-1-cyclohexen-1-yl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid. Grade: ≥95%. CAS No. 63531-93-1. Molecular formula: C20H28O3. Mole weight: 316.43. | |
| all-trans-3,4-Didehydro Retinoic Acid | all-trans-3,4-Didehydro Retinoic Acid is a Retinoic Acid derivative for the treatment of neuroinflammatory conditions. Synonyms: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4,6,8-nonatetraenoic Acid; 3-Dehydroretinoic Acid; 3,4-Didehydro-all-trans-retinoic Acid; 3,4-Didehydroretinoic Acid; Ro 8-7057; Vitamin A2 Acid; all-trans-Vitamin A2 Acid; all-trans-Vitamin A2 Acid. Grade: 96%. CAS No. 4159-20-0. Molecular formula: C20H26O2. Mole weight: 298.42. | |
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