BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| TAN-1511B | TAN-1511B is a lipopeptide antibiotic isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. It induced the secretion of both granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF). Synonyms: TAN 1511B. Molecular formula: C70H126N8O17S. Mole weight: 1383.9. |  |
| TAN-1511C | TAN-1511C is a lipopeptide antibiotic isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. It induced the secretion of both granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF). Synonyms: TAN 1511C. Molecular formula: C72H129N7O15S. Mole weight: 1364.9. | |
| TAN-1518A | TAN-1518A is a naphthacenecarboxamide antibiotic isolated from a culture broth of Streptomyces sp. AL-16012. It inhibits DNA topoisomerase I. Synonyms: TAN 1518A. Molecular formula: C39H41NO15. Mole weight: 763.7. | |
| TAN-1518B | TAN-1518B is a naphthacenecarboxamide antibiotic isolated from a culture broth of Streptomyces sp. AL-16012. It inhibits DNA topoisomerase I. Synonyms: TAN 1518B. CAS No. 154163-87-8. Molecular formula: C41H45NO15. Mole weight: 791.8. | |
| TAN-1813 | TAN-1813 is a Ras-farnesyltransferase inhibitor produced by a fungus strain, FL-41510. It inhibited rat brain farnesyltransferase and geranylgeranyltransferase I activity with IC50 values of 23 and 47 μg/mL, respectively. It also inhibited the proliferation of various human cancer cells. Synonyms: TAN 1813. Molecular formula: C26H35NO6. Mole weight: 457.6. | |
| TAN 420C | TAN-420C is an antibiotic produced by Streptomyces hygroscopicus. TAN 420C is known to exhibit antitumour activity. Synonyms: Dihydroherbimycin C. Grades: >95% by HPLC. CAS No. 91700-91-3. Molecular formula: C29H42N2O9. Mole weight: 562.65. | |
| TAN 420E | Antibiotic TAN 420E is a hydroquinone analogue of herbimycin A with antibacterial, antifungal and antiprotozoan activity. Synonyms: Dihydro-Herbimycin A; Dihydroherbimycin A. Grades: >95% by HPLC. CAS No. 91700-93-5. Molecular formula: C30H44N2O9. Mole weight: 576.68. | |
| TAN-931 | TAN-931 is a nonsteroidal aromatase inhibitor produced by Penicillium funiculosum No. 8974. Synonyms: Tan-931; Tan 931. CAS No. 127448-92-4. Molecular formula: C15H10O7. Mole weight: 302.23. | |
| TAN-950A | TAN-950A is an antifungal produced by Streptomyces platensis A-136. It is effective against Candida with MIC of 0.78-3.13 μg/mL. Synonyms: TAN 950A; TAN-950 A. Molecular formula: C6H8N2O4. Mole weight: 172.14. | |
| TAN-999 | TAN-999 is an indolocarbazole derivative produced by Streptomyces sp. C-71799. It can activate macrophage in mice. Synonyms: TAN 999. CAS No. 124843-68-1. Molecular formula: C29H26N4O4. Mole weight: 494.5. | |
| TATU | Synonyms: O-(7-Azabenzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; 2-(3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; 2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; O-(7-Azabenzotriazolyl)-tetramethyluronium tetrafluoroborate; TATU [O-(7-Azabenzotriazole-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate]; ACMC-209vlk; SCHEMBL153586. Grades: 99% (HPLC). CAS No. 873798-09-5. Molecular formula: C10H16BF4N6O. Mole weight: 323.08. | |
| Tazobactam sodium | A penicillin derived beta-lactamase inhibitor and antibacterial agent. Synonyms: Tazobactam sodium salt. CAS No. 89785-84-2. Molecular formula: C10H11N4NaO5S. Mole weight: 322.27. | |
| Teleocidin A1 | Teleocidin A1 is a powerful nematicide and acaricide produced by Streptomyces, which acts as an effective activator of protein kinase C, a tumor promoter, an inducer of colony stimulating factors, and regulator of expression of several genes. Synonyms: Lyngbyatoxin; Lyngbyatoxin-A. Grades: >98% by HPLC. CAS No. 70497-14-2. Molecular formula: C27H39N3O2. Mole weight: 437.62. | |
| Telomycin | Telomycin is an ester peptide antibiotic produced by Str. canus C-159. It has activity against gram-positive bacteria. Synonyms: A 128-HYP, A 128-OP. Grades: >98%. CAS No. 19246-24-3. Molecular formula: C59H77N13O19. Mole weight: 1272.32. | |
| Temocillin | Temocillin is a β-lactamase-resistant penicillin that effects against gram-negative bacteria. Synonyms: Temocillinum; BRL 17421; Negaban. CAS No. 66148-78-5. Molecular formula: C16H18N2O7S2. Mole weight: 414.45. | |
| Tenellin | It is a yellow pigment produced by species of the genus beauveria. It belongs to the rare 4-hydroxypyridone class containing a dienone side chain. Synonyms: 2(1H)-Pyridinone, 3-[(2E,4E,6R)-4,6-dimethyl-1-oxo-2,4-octadien-1-yl]-1,4-dihydroxy-5-(4-hydroxyphenyl)-. Grades: >95% by HPLC. CAS No. 53823-15-7. Molecular formula: C21H23NO5. Mole weight: 369.41. | |
| Tentoxin | Tentoxin, a cyclic tetrapeptide isolated from the plant pathogen A. alternata, has been found to restrain chloroplast development so that could be used as a natural herbicide. It is a selectively phytotoxic compound and used to eliminate polyphenol oxidase (PPO) activity from seedlings of higher plants. Synonyms: Cycloleucyl-N-methylalanylglycyl-N-methyl dehydrophenylalanine; (3S,6S,12Z)-12-benzylidene-1,6,7-trimethyl-3-(2-methylpropyl)-1,4,7,10-tetrazacyclododecane-2,5,8,11-tetrone; Cyclo(N-methyl-L-alanyl-L-leucyl-α,β-didehydro-N-methylphenylalanylglycyl); (Z)-Cyclic(N-methyl-L-alanyl-L-leucyl-α,β-didehydro-N-methylphenylalanylglycyl). Grades: ≥98%. CAS No. 28540-82-1. Molecular formula: C22H30N4O4. Mole weight: 414.50. | |
| Tenuazonic acid | Tenuazonic acid is a nitrogen-containing heterocyclic antibiotic produced by Alternaria tenuis Auct 430 and Asp. sp. 1404. It has inhibitory effect on enterovirus, respiratory virus, vaccinia virus and herpes simplex virus. It can inhibit KB cells and amoeba in dysentery. Synonyms: 3-acetyl-5-(butan-2-yl)-4-hydroxy-2,5-dihydro-1H-pyrrol-2-one. Grades: >98%. CAS No. 610-88-8. Molecular formula: C10H15NO3. Mole weight: 197.23. | |
| Tenuazonic acid Copper Salt | Tenuazonic Acid Copper Salt is an alternaria mycotoxin, found in common edible crops. It inhibits protein synthesis in fibroblasts. Synonyms: 3-Pyrrolin-2-one, 3-acetyl-5-sec-butyl-4-hydroxy-, L-, Copper Salt; L-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one Copper Salt; (5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one Copper Salt; AAC-toxin Copper Salt; L-Tenuazonic Acid Copper Salt. Grades: ≥98%. CAS No. 12427-40-6. Molecular formula: C20H28CuN2O6. Mole weight: 455.99. | |
| Ternatin | It is a cyclic peptide antifungal metabolite first isolated from the fungus didymocladium ternatum. It is a potent inhibitor of fat accumulation in 3T3-L1 murine adipocytes. Synonyms: cyclo[N-methyl-L-alanyl-N-methyl-D-alanyl-(3R)-3-hydroxy-D-leucyl-D-alloisoleucyl-N-methyl-L-alanyl-N-methyl-L-leucyl-L-leucyl]; 1,4,7,10,13,16,19-Heptaazacycloheneicosane; (-)-Ternatin; cyclo[DL-N(Me)Ala-DL-N(Me)Ala-DL-Leu(3-OH)-DL-xiIle-DL-N(Me)Ala-DL-N(Me)Leu-DL-Leu]. Grades: >98% by HPLC. CAS No. 148619-41-4. Molecular formula: C37H67N7O8. Mole weight: 737.97. | |
| Terpendole A | Terpendole A is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.29 μmol/L, and the CD50 that causes 50% cell damage is greater than 23.4 μmol/L. Molecular formula: C32H41NO6. Mole weight: 535.67. | |
| Terpendole C | Terpendole C is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.46 μmol/L, and the CD50 that causes 50% cell damage is greater than 24.1 μmol/L. Synonyms: (3S, 4aR, 4bR, 5aS, 5bS, 7aS, 13bS, 13cR, 15aS, 16aS)-1, 1, 13b, 13c-tetramethyl-3-(2-methylprop-1-en-1-yl)-1, 4a, 4b, 6, 7, 7a, 8, 13, 13b, 13c, 14, 15, 15a, 16a-tetradecahydro-5bH-[1, 3]dioxino[5'', 4'':2', 3']oxireno[2'', 3'':4', 4a']chromeno[5', 6':6, 7]indeno[1, 2-b]indol-5b-ol; (-)-terpendole C. Grades: >98%. CAS No. 156967-65-6. Molecular formula: C32H41NO5. Mole weight: 519.67. | |
| Terpendole E | Terpendole E is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.29 μmol/L, and the CD50 that causes 50% cell damage is greater than 23.4 μmol/L. Synonyms: (2S, 4R, 4aR, 4bR, 6aS, 12bS, 12cS, 14aS)-2-(2-Hydroxypropan-2-yl)-4a, 12b, 12c-trimethyl-3, 4, 4a, 4b, 5, 6, 6a, 7, 12, 12b, 12c, 13, 14, 14a-tetradecahydro-2H-chromeno[5', 6':6, 7]indeno[1, 2-b]indol-4-ol. Grades: >98%. CAS No. 167427-23-8. Molecular formula: C28H39NO3. Mole weight: 437.61. | |
| Terpendole L | Terpendole F is an acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor produced by Albophoma yamenashiensis. The IC50 that inhibits ACAT in macrophages is 0.29 μmol/L, and the CD50 that causes 50% cell damage is greater than 23.4 μmol/L. Synonyms: (3S, 4aR, 4bR, 5aS, 5bS, 7aS, 13bS, 13cR, 15aS, 16aS)-1, 1, 13b, 13c-tetramethyl-9-(3-methylbut-2-en-1-yl)-3-(2-methylprop-1-en-1-yl)-1, 4a, 4b, 6, 7, 7a, 8, 13, 13b, 13c, 14, 15, 15a, 16a-tetradecahydro-5bH-[1, 3]dioxino[5'', 4'':2', 3']oxireno[4', 4a']chromeno[5', 6':6, 7]indeno[1, 2-b]indol-5b-ol. Molecular formula: C37H49NO5. Mole weight: 587.79. | |
| Terpentecin | Terpentecin is an antibiotic produced by Kitasatosporia sp. MF 730-N6. It has strong anti-gram-positive and gram-negative bacteria activity, and also has an effect on mycobacteria. It can prolong the survival time of mice suffering from leukemia L-1210, P388 and Ehrlich ascites cancer. Synonyms: [(2S)-2-{(1R)-1-hydroxy-2-[(1S,2S,3R,4aS,8aS)-3-hydroxy-1,2,4a,5-tetramethyl-4-oxo-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl]ethyl}oxiran-2-yl](oxo)acetaldehyde. Grades: >98%. CAS No. 100440-25-3. Molecular formula: C20H28O6. Mole weight: 364.43. | |
| Terphenyllin | Terphenyllin is a naturally abundant p-terphenyl metabolite isolated from the coral derived fungus Aspergillus candidus, has significant α-glucosidase inhibitory activity. Grades: >99% by HPLC. CAS No. 52452-60-5. Molecular formula: C20H18O5. Mole weight: 338.35. | |
| Terrecyclic acid | Terrecyclic acid is an antibiotic produced by Asptrgillus terreus No. 14. It has weak anti-Gram-positive bacteria and fungus activity, and has an inhibitory effect on leukemia cells P388. Synonyms: Terrecyclic acid A; (+)-terrecyclic acid A. Grades: >95% by HPLC. CAS No. 83058-94-0. Molecular formula: C15H20O3. Mole weight: 248.32. | |
| Terreic acid | Terreic acid is an antibiotic produced by Asp.terreus 5378 and Asp. parvulus. It has weak antibacterial and fungal activity. It also acts as an inhibitor of Bruton's tyrosine kinase (BTK). Synonyms: (-)-Terreic Acid. Grades: >98%. CAS No. 121-40-4. Molecular formula: C7H6O4. Mole weight: 154.12. | |
| Terrein | Terrein is an antibiotic produced by Asp. terreus 45 and AC 100. Activity against Gram-positive bacteria. Synonyms: 4S,5R-dihydroxy-3-(1E)-1-propen-1-yl-2-cyclopenten-1-one. Grades: >98%. CAS No. 582-46-7. Molecular formula: C8H10O3. Mole weight: 154.16. | |
| Terreulactone A | Tetracycline A is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.23 μmol/L. Synonyms: 13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4, 14, 19, 19-tetramethyl-5, 9, 18-trioxapentacyclo[14.2.1.01, 14.04, 13.06, 11]nonadeca-6(11), 7-diene-10, 15, 17-trione. Molecular formula: C28H30O9. Mole weight: 510.53. | |
| Terreulactone B | Tetracycline B is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.09 μmol/L. Molecular formula: C27H30O7. Mole weight: 466.52. | |
| Terreulactone C | Tetracycline C is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.06 μmol/L. Molecular formula: C27H32O7. Mole weight: 468.54. | |
| Terreulactone D | Tetracycline D is an acetylcholinesterase (AchE, EC3. 1.1.7) inhibitor produced by Aspergillus terreus. It has a strong inhibition of AchE activity with IC50 of 0.42 μmol/L. Molecular formula: C30H36O10. Mole weight: 556.60. | |
| Territrem B | Territrem B is a mycotoxin originally isolated from Aspergillus terreus that irreversibly inhibits acetylcholinesterase (AChE). Synonyms: (4aR,6aR,12aS,12bS)-4a,6,6a,12,12a,12b-Hexahydro-4a,12a-dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-trimethoxyphenyl)-4H,11H-naphtho[2,1-b]pyrano[3,4-e]pyran-1,11(5H)-dione; [4aR-(4aα, 6aβ, 12aα, 12bβ)]-4a, 6, 6a, 12, 12a, 12b-Hexahydro-4a, 12a-dihydroxy-4, 4, 6a, 12b-tetramethyl-9-(3, 4, 5-trimethoxyphenyl)-4H, 11H-naphtho[2, 1-b]pyrano[3, 4-e]pyran-1, 11(5H)-dione. Grades: ≥95%. CAS No. 70407-20-4. Molecular formula: C29H34O9. Mole weight: 526.57. | |
| Tert-Butyldimethylsilyl chloride | Used to protect alcohols during organic synthesis. Synonyms: tert-Butyldimethylchlorosilane; TBDMSCL; t-Butyldimethylchlorosilane; TBDMS chloride; tert-Butyl(chloro)dimethylsilane; TBSCl; Silane, chloro(1,1-dimethylethyl)dimethyl-; t-butyldimethylsilyl chloride; Chloro-tert-butyldimethylsilane; Chloro(1,1-dimethylethyl)dimethylsilane; TBS-Cl; bdcs; tbdms-cl. Grades: ≥ 99% (GC). CAS No. 18162-48-6. Molecular formula: C6H15ClSi. Mole weight: 150.72. | |
| tert-Butyldiphenylsilyl chloride | Synonyms: tert-Butylchlorodiphenylsilane; Diphenyl-tert-butylchlorosilane. Grades: ≥ 98% (GC). CAS No. 58479-61-1. Molecular formula: C16H19ClSi. Mole weight: 274.84. | |
| tert-Butyl Hydrogen Hexadecanedioate | Synonyms: 16-(tert-butoxy)-16-oxohexadecanoic acid; Hexadecanedioic acid mono-tert-butyl ester. Grades: ≥98%. CAS No. 843666-27-3. Molecular formula: C20H38O4. Mole weight: 342.5. | |
| Tetracycline | Tetracycline is an antibiotic produced by various Streptomyces such as Str. viridifaciens BL-567201 and Str. aureofacies NRRL 2209. It has antibacterial and mycobacterial activity, and has cross-resistance with oxytetracycline and chlortetracycline. Human serum does not affect its antibacterial activity. It has the effect of inhibiting large viruses and the main gram. It is widely used in clinics to treat chlamydia, rickettsia, mycoplasma and bacterial infections. Uses: Antibiotics, tetracycline; protein synthesis inhibitors. Synonyms: Oxytetracycline EP Impurity B; (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide; Abramycin; Achromycin; (-)-Tetracycline; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α, 4aα, 5aα, 6β, 12aα)]-; NSC 108579; Dispatetrin; Economycin; Biocycline; Cytome; Limecycline; Medocycline; Veracin; Oxytetracycline Dihydrate EP Impurity B; Oxytetracycline Hydrochloride EP Impurity B. Grades: >98% by HPLC. CAS No. 60-54-8. Molecular formula: C22H24N2O8. Mole weight: 444.43. | |
| Tetradecanoyl-L-homoserine lactone | It is an active quorum sensing modulator first recognised in rhodobacter capsulatus. It has been detected in hundreds of bacterial species. Synonyms: C14-HSL; tDHL; N-Tetradecanoyl-L-homoserine lactone; (S)-N-(tetrahydro-2-oxo-3-furanyl)tetradecanamide; N-[(3S)-Tetrahydro-2-oxo-3-furanyl]tetradecanamide; (S)-N-tetradecanoyl-HSL; Tetradecanoylhomoserine lactone; N-Myristoyl-L-homoserine lactone. Grades: >99% by HPLC. CAS No. 202284-87-5. Molecular formula: C18H33NO3. Mole weight: 311.46. | |
| Tetrafibricin | Tetrafibricin is a fibrinogen antagonist produced by Str. neyagawaensis NR0577. Tetrafibricin has a strong inhibitory effect on the binding of fibrinogen to the GP IIb/IIIa receptor with an IC50 of 46 nmol/L, and an IC50 of 46 mol/L for the inhibition of HeLa cell toxicity. Synonyms: 11,15,17,19,23,25,27,29,33,37-Decahydroxy-12-methyl-13-oxo-40-amino-2,4,6,8,20,30,34-tetracontaheptaenoic acid; 2,4,6,8,20,30,34-Tetracontaheptaenoic acid, 40-amino-11,15,17,19,23,25,27,29,33,37-decahydroxy-12-methyl-13-oxo-. CAS No. 151705-56-5. Molecular formula: C41H67NO13. Mole weight: 781.97. | |
| Tetrahymanol | Tetrahymanol is a natural compound isolated from Rhodopseudomonas palustris. Synonyms: Gammaceran-3β-ol; Wallichiniol; gammaceran-3beta-ol; 5α-Gammaceran-3β-ol; Gammaceran-3-ol, (3β)-. Grades: 98.0%. CAS No. 2130-17-8. Molecular formula: C30H52O. Mole weight: 428.73. | |
| Tetrahymanol acetate | Tetrahymanol acetate is a natural compound isolated from Bradyrhizobium japonicum. Synonyms: Tetrahymanolacetate; Acetic acid 5alpha-gammaceran-3beta-yl ester; tetrahymanyl acetate; Gammaceran-3-ol, 3-acetate, (3β)-; Acetic acid (3S,6aR,14bR)-4,4,6a,6b,9,9,12a,14b-octamethyl-docosahydro-picen-3-yl ester. Grades: 98.0%. CAS No. 2130-22-5. Molecular formula: C32H54O2. Mole weight: 470.77. | |
| Tetrahymanone | Tetrahymanone is isolated from Bradyrhizobium japonicum. Synonyms: Gammaceran-3-one; (6aR,14bR)-4,4,6a,6b,9,9,12a,14b-Octamethyl-icosahydro-picen-3-one. Grades: ≥96%. CAS No. 17822-06-9. Molecular formula: C30H50O. Mole weight: 426.72. | |
| Tetrakis (triphenylphosphine)palladium (0) | Pd(PPh3)4 is widely used as a catalyst for palladium-catalyzed coupling reactions. Prominent applications include the Heck reaction, Suzuki coupling, Stille coupling, Sonogashira coupling, and Negishi coupling. Synonyms: Pd(PPh3)4. Grades: ≥ 99.5% (≥ 9% Pd, Assay). CAS No. 14221-01-3. Molecular formula: [(C6H5)3P]4Pd. Mole weight: 1155.58. | |
| Tetranactin | It is a member of the macrotetrolide complex produced by a range of streptomyces sp. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Unlike the other macrotetrolides, tetranactin exhibits potent insecticidal activity. It is a glycoprotein transportation inhibitor, an immunosuppressant, an antiproliferative and an antiallergic agent. Synonyms: 5,14,23,32-Tetrademethyl-5,14,23,32-tetraethylnonactin; S-3466-C; 4, 13, 22, 31, 37, 38, 39, 40-Octaoxapentacyclo[32.2.1.17, 10.116, 19.125, 28]tetracontane-3, 12, 21, 30-tetrone, 5,14,23,32-tetraethyl-2,11,20,29-tetramethyl-, (1R, 2R, 5R, 7R, 10S, 11S, 14S, 16S, 19R, 20R, 23R, 25R, 28S, 29S, 32S, 34S)-. Grades: >95% by HPLC. CAS No. 33956-61-5. Molecular formula: C44H72O12. Mole weight: 793.04. | |
| Tetrangomycin | Tetrangomycin is a quinone antibiotic produced by Str. rimosus var. sp. NRRL 3016. It has activity against gram-positive bacteria, but has no protective effect on mice infected with the Smith strain of golden staphylococcus aureus. Synonyms: (+)-3,4-dihydro-3,8-dihydroxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione; (-)-tetrangomycin; Benzanthramycin. CAS No. 7351-8-8. Molecular formula: C19H14O5. Mole weight: 322.31. | |
| Tetranolin | Tetranolin is a lactone antibiotic produced by Act. sp. SS-1018. It has anti-Gram-positive bacteria activity and weak anti-mycobacterial activity. Synonyms: Lissoclinolide; Kissoclinolide; lissoclinolide tetrenolin. Grades: >98%. CAS No. 132074-82-9. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Tetrazomine | Tetrazomine is an antibiotic produced by Saccharothrix mulabilis subsp. chichijimaensis. It is active against gram-positive bacteria, gram-negative bacteria and mycobacteria. It has cytotoxic activity and inhibits lymphoid leukemia L1210 and leukemia P388 with IC50 of 0.047 and 0.0140 μg/mL, respectively. CAS No. 132073-72-4. Molecular formula: C24H34N4O5. Mole weight: 458.55. | |
| Tetrodecamycin | It is produced by the strain of Streptomyces nashvillensis MJ885-mF8. It has anti-gram-positive bacteria (MIC is 6.25-12.5 μg/mL) and PasteureRci pisciccida (MIC is 1.56-3.12 μg/mL) activity. Synonyms: (-)-tetrodecamycin; 5,11-Methanofuro(3,4-d)(3)benzoxonin-1,12(3H,5H)-dione,6,6a,7,8,9,10,10a,11-octahydro-6,6a-dihydroxy-11,13-dimethyl-3-methylene-, (5R-(5R*,6S*,6aR*,10aR*,11S*,13R*))-. CAS No. 156980-57-3. Molecular formula: C18H22O6. Mole weight: 334.36. | |
| Tetromycin A | An unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. It is an antibiotic produced by Streptomyces. It has pronounced activity against antibiotic susceptible and resistant gram-positive bacteria including MRSA. It appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: [1S-(1R*, 4R*, 4aR*, 6aS*, 7E, 11E, 12aS*, 15S*, 16aR*, 20aR*, 20bS*)]-4-(acetyloxy)-2, 3, 4, 4a, 6a, 9, 10, 12a, 15, 16, 20a, 20b-dodecahydro-21-hydroxy-1, 6, 7, 11, 12a, 14, 15, 20a-octamethyl-18H-16a, 19-Metheno-16aH-benzo[b]naphth[2, 1-j]oxacyclotetradecin-18, 20(1H)-dione; 8-Demethyl-17,32-dideoxy-12,20-dimethyl-kijanolide 9-Acetate. Grades: >99% by HPLC. CAS No. 180027-83-2. Molecular formula: C36H48O6. Mole weight: 576.76. | |
| Tetromycin B | An unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. It is an antibiotic produced by Streptomyces. It has pronounced activity against antibiotic susceptible and resistant gram-positive bacteria including MRSA. It appears to target the phosphatidylinositide-3-kinase/akt signalling pathway. Synonyms: 8-Demethyl-17,32-dideoxy-12,20-dimethyl-kijanolide; [1S-(1R*, 4R*, 4aR*, 6aS*, 7E, 11E, 12aS*, 15S*, 16aR*, 20aR*, 20bS*)]-2, 3, 4, 4a, 6a, 9, 10, 12a, 15, 16, 20a, 20b-Dodecahydro-4, 21-trihydroxy-1, 6, 7, 11, 12a, 14, 15, 20a-octamethyl-18H-16a, 19-metheno-16aH-benzo[b]naphth[2, 1-j]oxacyclotetradecin-18, 20(1H)-dione. Grades: >99% by HPLC. CAS No. 180027-84-3. Molecular formula: C34H46O5. Mole weight: 534.73. | |
| Tetronasin | Tetronasin is extracted from Streptomyces longisporoflavus. It has anti-gram-positive bacteria and anti-eimeria tenella activity. Synonyms: Tetronasina; Tetronasine; Tetronasinum; Antibiotic M 139603; ICI 139603; M 139603. Molecular formula: C35H54O8. Mole weight: 602.80. | |
| Tetronomycin Sodium | Tetronomycin Sodium is a polycyclic ionophore polyether antibiotic produced by Str. sp. nov. S53161/A. It has anti-Gram-positive bacteria, Neisseria and Mycoplasma activity. Molecular formula: C34H49NaO8. Mole weight: 608.74. | |
| Tetronothiodin | Tetronothiodin is a trypsin secretin type B receptor antagonist produced by Str. sp. NR0489. Tetronothiodin can inhibit the binding of trypsin C-terminal 8 peptide to rat cortical trypsin B receptor, with IC50 of 3.6 μmol/L. CAS No. 139643-79-1. Molecular formula: C31H38O8S. Mole weight: 570.69. | |
| Thailanstatin B | Thailanstatin B is a pre-mRNA splicing inhibitor. Thailanstatin B is used as a cytotoxin for ADCs. Synonyms: EX-A5053. CAS No. 1426953-23-2. Molecular formula: C28H42ClNO9. Mole weight: 572.1. | |
| Thailanstatin C | Thailanstatin C is an antiproliferative agent and pre-mRNA splicing inhibitor (IC50 = 6.84 μM) from Burkholderia thailandensis MSMB43. Synonyms: (1S,5R)-1,5-Anhydro-1-(carboxymethyl)-3-C-(chloromethyl)-2-deoxy-5-{(1E,3E)-5-[(2S,3S,5R,6R)-5-{[(2Z,4S)-4-(isobutyryloxy)-2-pentenoyl]amino}-3,6-dimethyltetrahydro-2H-pyran-2-yl]-3-methyl-1,3-pentadien-1-yl}-D-erythro-pentitol; D-arabino-Heptonic acid, 3,7-anhydro-5-C-(chloromethyl)-2,4-dideoxy-7-C-[(1E,3E)-3-methyl-5-[(2S,3S,5R,6R)-tetrahydro-3,6-dimethyl-5-[[(2Z,4S)-4-(2-methyl-1-oxopropoxy)-1-oxo-2-penten-1-yl]amino]-2H-pyran-2-yl]-1,3-pentadien-1-yl]-, (7R)-. Grades: ≥95%. CAS No. 1426953-24-3. Molecular formula: C30H46ClNO9. Mole weight: 600.14. | |
| Thailanstatin D | Thailanstatin D inhibits AR-V7 gene splicing by interfering the interaction between U2AF65 and SAP155 and preventing them from binding to polypyrimidine tract located between the branch point and the 3' splice site. Thailanstatin D exhibits a potent tumor inhibitory effect on human CRPC xenografts leading to cell apoptosis. Synonyms: Spliceostatin C. CAS No. 1609105-89-6. Molecular formula: C28H41NO8. Mole weight: 519.63. | |
| Thapsigargicin | It is a hexaoxygenated tetra-acylated sesquiterpene lactone tetraester isolated from roots of Thapsia garganica. It induces mast cell degranulation and histamine release. Synonyms: Hexanoic acid, (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-buten-1-yl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl ester. Grades: ≥90%. CAS No. 67526-94-7. Molecular formula: C32H46O12. Mole weight: 622.70. | |
| Thapsigargin | Potent, cell-permeable, IP3-independent intracellular calcium releaser. Blocks the transient increase in intracellular Ca2+ induced by angiostatin and endostatin. Induces apoptosis by disrupting intracellular free Ca2+ levels; incorporated into chemotherapeutic prodrug formulations. In cells, sarco/endoplasmic calcium ATPases (SERCAs) transport free calcium into the sarcoplasmic and endoplasmic reticula, lowering intracellular calcium levels to stop signaling through this cation. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM). Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells. In vivo, thapsigargin and related sesquiterpene lactones have anti-inflammatory and anti-cancer effects. Uses: Enzyme inhibitors. Synonyms: Octanoic acid. Grades: >99%. CAS No. 67526-95-8. Molecular formula: C34H50O12. Mole weight: 650.75. | |
| Thelephoric acid | Thelephoric acid is a terphenylquinone pigment found in several fungi, such as Omphalotus subilludens and Polyozellus multiplex. It is derived from atromentin, and its precusor can be from cyclovariegatin. Thelephoric acid has been shown to inhibit prolyl endopeptidase, an enzyme that plays a role in processing proteins (specifically, amyloid precursor protein) in Alzheimer's disease. Synonyms: 2,3,8,9-Tetrahydroxybenzo[1,2-b:4,5-b']bisbenzofuran-6,12-dione; Thelephorsaure; PM-B; 2,3'-Carbonyl-3,2'-carbonylbis(5,6-dihydroxybenzofuran); Thelephate. CAS No. 479-64-1. Molecular formula: C18H8O8. Mole weight: 352.25. | |
| Thermorubin | Thermorubin A is an antibiotic produced by Thermoactinomyces antibioticus TA/124. It has broad-spectrum antibacterial effect, but weaker effect on mycobacteria. Serum has the effect of reducing antibacterial activity. It has a protective effect on mice infected with Staphylococcus aureus by intraperitoneal administration. Synonyms: Thermorubin A. CAS No. 37577-75-6. Molecular formula: C32H24O12. Mole weight: 600.52. | |
| Thiamphenicol | Thiamphenicol is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol. Thiamphenicol is used to treat chicken intestinal infections caused by E. coli. Uses: Anti-bacterial agents. Synonyms: Thiophenicol. Grades: >98%. CAS No. 15318-45-3. Molecular formula: C12H15Cl2NO5S. Mole weight: 356.22. | |
| Thiazinotrienomycin A | Thiazinotrienomycin A is an ansa antibiotic produced by Str. sp. MJ672-m3. It has the effect of inhibiting cancer cells, and the IC50 for inhibiting HeLa cells is 5.0 ng/mL. CAS No. 165337-93-9. Molecular formula: C38H49N3O8S. Mole weight: 707.87. | |
| Thiazinotrienomycin E | Thiazinotrienomycin E is an ansa antibiotic produced by Str. sp. MJ672-m3. It has the effect of inhibiting cancer cells, and the IC50 for inhibiting HeLa cells is 13 ng/mL. CAS No. 165337-97-3. Molecular formula: C38H51N3O8S. Mole weight: 709.89. | |
| Thiazinotrienomycin F | Thiazinotrienomycin F is an ansa antibiotic produced by Str. sp. MJ672-m3. It can inhibit the growth of tumor cells such as NCI-H522, NCI-H469, OVCAR-5, St-4 and BSY-1. Molecular formula: C37H47N3O7S. Mole weight: 677.85. | |
| Thiazinotrienomycin G | Thiazinotrienomycin G is an ansa antibiotic produced by Str. sp. MJ672-m3. It can inhibit the growth of tumor cells such as NCI-H522, NCI-H469, OVCAR-5, St-4 and BSY-1. Molecular formula: C37H49N3O7S. Mole weight: 679.86. | |
| Thidiazuron | A cytokinin-lilke plant hormone routinely used to promote plant tissue regeneration. Synonyms: Defolit; Dropp; Urea, N-Phenyl-N'-1,2,3-Thiadiazol-5-Yl-; TDZ. Grades: ≥95%. CAS No. 51707-55-2. Molecular formula: C9H8N4OS. Mole weight: 220.25. | |
| Thielavin A | Thielavin A is a glucose-6-phosphatase (G6Pase) inhibitor produced by Chaetomium carinthiacum. Grades: >95% by HPLC. CAS No. 71950-66-8. Molecular formula: C29H30O10. Mole weight: 538.54. | |
| Thielavin B | Thiourea B is a fungal metabolite that contains O-substituted salicylic acid. It is a fungal metabolite closely related to thiobactin A. It is an effective inhibitor of phospholipase C, which can inhibit the formation of peptidoglycan and the biosynthesis of prostaglandin. Synonyms: Thielavin-B. Grades: >95% by HPLC. CAS No. 71950-67-9. Molecular formula: C31H34O10. Mole weight: 566.59. | |
| Thielavin D | Thielavin D is a glucose-6-phosphatase (G6Pase) inhibitor produced by Chaetomium carinthiacum. Molecular formula: C30H32O10. Mole weight: 552.57. | |
Our database is helping our users find suppliers everyday.
