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Alalevonadifloxacin
Alalevonadifloxacin is a quinolone antibacterial. It is a DNA gyrase and DNA topoisomerase inhibitor. Alalevonadifloxacin is potentially useful to treat bacterial Gram-positive, Gram-negative and anaerobic infections. Phase II clinical trials for the treatment of Methicillin-resistant Staphylococcus aureus infections and Skin and soft tissue infections are on-going. Uses: Methicillin-resistant staphylococcus aureus infections; skin and soft tissue infections. Synonyms: WCK2349; WCK 2349; WCK-2349; (5S)-8-[4-(L-alanyloxy)piperidin-1-yl]-9-fluoro-5-methyl-1-oxo-6,7-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid. Grade: 98%. CAS No. 706809-20-3. Molecular formula: C22H26FN3O5. Mole weight: 431.46.
Alaproclate hydrochloride
Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal studies. Alaproclate is a selective serotonin reuptake inhibitor (SSRI) and inhibits depletion of a serotonin (5-HT) induced by 4-methyl-α-methyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus and striatum. It has also been found to act as a non-competitive NMDA receptor antagonist although without discriminative stimulus properties similar to phencyclidine. Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons. Synonyms: GEA 654; A03. Grade: ≥95%. CAS No. 60719-83-7. Molecular formula: C13H18ClNO2·HCl. Mole weight: 292.20.
Alaptide
Permeation of Indomethacin through Skin Using Nanonized Alaptide. Synonyms: Cyclo(1-amino-1-cyclopentanecarbonyl-L-alanyl). Grade: > 95%. CAS No. 90058-29-0. Molecular formula: C9H14N2O2. Mole weight: 182.22.
a-L-Arabinopyranosylnitromethane
a-L-Arabinopyranosylnitromethane, a compound with remarkable potential in the biomedical industry due to its noteworthy anti-inflammatory and antioxidant properties, finds application in the treatment of a plethora of diseases including cancer, diabetes, and cardiovascular disorders. Synonyms: 2,6-Anhydro-1-deoxy-1-nitro-L-mannitol. CAS No. 113972-91-1. Molecular formula: C6H11NO6. Mole weight: 193.15.
Alarelin
Alarelin is a synthetic analog of Gonadotropin-releasing hormone (GnRH) used primarily for its effects on the reproductive system. It acts as a GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Alarelin is used in the treatment of conditions such as endometriosis, uterine fibroids, and prostate cancer, as well as in assisted reproductive technologies. Synonyms: 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-; Luteinizing hormone-releasing factor (pig), 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-; AY 25205; Dalarelin; Dalareline; L 4513; LHRH-A2; LRH-A2; Luteinizing hormone-releasing hormone analog 2; Surfagon; TAP 127; Wy 18481; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide; (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH; Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; LHRH-A; 6-D-Ala-10-D-gly-LHRH-ethylamide; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide. Grade: 95%. CAS No. 52435-06-0. Molecular formula: C56H78N16O12. Mole weight: 1167.32.
Alatrofloxacin Mesylate
Alatrofloxacin Mesylate is the mesylate salt form of the fluoroquinolone derivative Alatrofloxacin, a type II DNA topoisomerase inhibitor that has been developed as an antibacterial agent. Synonyms: L-Alaninamide, L-alanyl-N-[(1α,5α,6α)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, methanesulfonate (1:1); L-Alaninamide, L-alanyl-N-[(1α,5α,6α)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, monomethanesulfonate; L-Alaninamide, L-alanyl-N-[3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, (1α,5α,6α)-, monomethanesulfonate; Adrenochrome monoaminoguanidine mesilate; CP 116517; CP 116517-27; Trovan IV; Turvel IV; 7-((1R,5S,6s)-6-((S)-2-((S)-2-aminopropanamido)propanamido)-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid compound with methanesulfonic acid (1:1). Grade: ≥95%. CAS No. 146961-77-5. Molecular formula: C27H29F3N6O8S. Mole weight: 654.61.
ALB-109564
ALB 109564(a) is a semi-synthetic derivative of the vinka alkaloid vinblastine with potential antineoplastic activity. Tubulin inhibitor ALB 109564(a) binds to tubulin monomers and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle. Synonyms: ALB-109564; ALB 109564; ALB109564; ALB 109564(a); Vincaleukoblastine, 12'-(methylthio)-, hydrochloride (1:2). CAS No. 854756-74-4. Molecular formula: C47H60N4O9S. Mole weight: 857.07.
ALB 109564(a) dihydrochloride
ALB 109564(a) is a Tubulin inhibitor as a semi-synthetic derivative of the vinka alkaloid originated by AMRI. It can bind to tubulin monomers and inhibit microtubule formation, this leads to the disruption of mitotic spindle assembly and arrest of tumor cells in the G2/M phase of the cell cycle. Phase I clinical trials for Solid tumours is on going. Uses: Solid tumours. Synonyms: ALB-109564 dihydrochloride; ALB 109564 dihydrochloride; ALB109564 dihydrochloride; Vincaleukoblastine 12(methylthio) hydrochloride (1:2); (3aR,3a1R,4R,5S,5aR,10bR)-methyl 4-acetoxy-3a-ethyl-9-((3S,5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-13-(methylthio)-2,4,5,6,7,8,9,10-octahydro-1H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate. Grade: 98%. CAS No. 1300114-12-8. Molecular formula: C47H60N4O9S. Mole weight: 930.00.
Albaconazole
Albaconazole is a triazole antifungal agent. It shows potent activity against species of Candida, Cryptococcus and Aspergillus. Synonyms: 7-chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one. CAS No. 187949-02-6. Molecular formula: C20H16ClF2N5O2. Mole weight: 431.8.
AlbA-DCA
AlbA-DCA induces a marked increase in intracellular ROS and alleviates the accumulation of lactic acid in tumor microenvironment (TME), and also selectively kills cancer cells and induces apoptosis. CAS No. 2413716-79-5. Molecular formula: C43H67Cl2NO12. Mole weight: 860.90.
Albendazole-2-aminosulfone hydrochloride
Albendazole-2-aminosulfone hydrochloride is an impurity of Albendazole. Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations. Synonyms: 5-(Propane-1-sulfonyl)-1H-benzoimidazol-2-ylamine hydrochloride. Molecular formula: C10H13N3O2S.HCl. Mole weight: 275.759.
Albendazole EP Impurity A
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). Synonyms: Desmethoxycarbonyl Albendazole; 5-(Propylsulphanyl)-1H-benzimidazol-2-amine. Grade: > 95%. CAS No. 80983-36-4. Molecular formula: C10H13N3S. Mole weight: 207.3.
Albendazole EP Impurity C
A metabolite of Albendazole. Albendazole is a benzimidazole compound used as a medication indicated for the treatment of a variety of worm infestations. Uses: Anthelmintics. Synonyms: [5-(Propane-1-sulfonyl)-1H-benzoimidazol-2-yl]-carbamic acid methyl ester; Albendazole sulfone. Grade: > 95%. CAS No. 75184-71-3. Molecular formula: C12H15N3O4S. Mole weight: 297.33.
Albendazole EP Impurity D
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). Synonyms: Desmethoxycarbonyl Albendazole Sulfone. Grade: > 95%. CAS No. 80983-34-2. Molecular formula: C10H13N3O2S. Mole weight: 239.3.
Albendazole EP Impurity F
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). Synonyms: Methyl [5-(methylsulphanyl)-1H-benzimidazol-2-yl]carbamate. Grade: > 95%. CAS No. 80983-45-5. Molecular formula: C10H11N3O2S. Mole weight: 237.28.
Albendazole EP Impurity G
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). Synonyms: Methyl (6-chloro-1H-benzo[d]imidazol-2-yl)carbamate. CAS No. 20367-38-8. Molecular formula: C9H8ClN3O2. Mole weight: 225.63.
Albendazole EP Impurity H
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). CAS No. 2469260-71-5. Molecular formula: C15H19N3O3S. Mole weight: 321.40.
Albendazole EP Impurity J
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). CAS No. 946498-41-5. Molecular formula: C9H7Cl2N3O2. Mole weight: 260.07.
Albendazole EP Impurity K
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). CAS No. 70484-51-4. Molecular formula: C13H17N3O2S. Mole weight: 279.36.
Albendazole EP Impurity L
An impurity of Albendazole, a medication used to treat certain tapeworm infections (such as neurocysticercosis and hydatid disease). Synonyms: Methiazole. CAS No. 108579-67-5. Molecular formula: C12H15N3O2S. Mole weight: 265.33.
Albendazole Impurity 1
An impurity of Albendazole. Synonyms: 4-(Propylthio)-1,2-phenylenediamine. Grade: > 95%. CAS No. 66608-52-4. Molecular formula: C9H14N2S. Mole weight: 182.29.
Albendazole oxide
Albendazole Oxide is a tubulin polymerization or assembly inhibitor. It can be used for livestock and poultry nematode disease, tapeworm disease and trematodiasis. Synonyms: Albendazole EP Impurity B; Ricobendazole; RS 8852; RS-8852; RS8852. Grade: >98%. CAS No. 54029-12-8. Molecular formula: C12H15N3O3S. Mole weight: 281.33.
Albitiazolium bromide
Albitiazolium bromide is a choline analogue acts as a cholinergic receptor antagonists, inhibits choline transport into Plasmodium-infected erythrocytes, thus preventing parasite PC biosynthesis, and also to interact with plasmodial haemoglobin degradation in the food vacuole. Uses: Cholinergic receptor antagonists. Synonyms: SAR97276; SAR-97276; SAR 97276; Albitiazolium bromide1,12-bis[4-Methyl-5-(2-hydroxyethyl)thiazol-3-ium-3-yl]dodecane dibromide; 2-[3-[12-[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]dodecyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol; dibromide. Grade: ≥95%. CAS No. 321915-72-4. Molecular formula: C24H42Br2N2O2S2. Mole weight: 614.54.
Albomitomycin C
Albomitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. Synonyms: (1S,2S,4S,5R,6S,6aR,10aS,11S)-8-Amino-6-[[(aminocarbonyl)oxy]methyl]-2,3,6,6a-tetrahydro-5-methoxy-9-methyl-1,2,5-metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione; Antibiotic CX 1; [1S-(1α,2α,4β,5β,6α,6aα,10aR*,11R*)]-8-amino-6-[[(aminocarbonyl)oxy]methyl]-2,3,6,6a-tetrahydro-5-methoxy-9-methyl-1,2,5-Metheno-1H,5H-imidazo[2,1-i]indole-7,10-dione; Mitomycin EP Impurity D. Grade: > 95%. CAS No. 111750-67-5. Molecular formula: C15H18N4O5. Mole weight: 334.33.
Albuterol Aldehyde
An impurity of salbutamol.Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Salbutamol EP Impurity D; Levalbuterol USP RC D; Salbutamol Aldehyde Impurity; 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)-2-hydroxybenzaldehyde. Grade: ≥98%. CAS No. 156339-88-7. Molecular formula: C13H19NO3. Mole weight: 237.29.
Albuterol Related Compound A
An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: α-[[(1,1-Dimethylethyl)amino]methyl]-4-hydroxy-3-methylbenzenemethanol. Grade: > 95%. CAS No. 18910-68-4. Molecular formula: C13H21NO2. Mole weight: 223.32.
Albuterol Related Compound D
An impurity of salbutamol. Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Synonyms: Salbutamol sulfate impurity L [EP]; (+/-)-Chloroalbuterol; Chloroalbuterol. CAS No. 898542-81-9. Molecular formula: C13H20ClNO3. Mole weight: 273.75.
Albutrepenonacog alfa is a long-acting recombinant coagulation factor IX albumin fusion protein. It was approved for the treatment of hemophilia B. It can reduce the risk of bleeding episodes in patients with hemophilia B. Uses: The treatment of hemophilia b. Synonyms: Idelvion; rIX-RFP.
Alcaftadine
Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis. Uses: Histamine h1 antagonists. Synonyms: Lastacaft. Grade: 0.98. CAS No. 147084-10-4. Molecular formula: C19H21N3O. Mole weight: 307.397.
Alcaftadine-13C-D3
Alcaftadine-13C-D3 is a labelled Alcaftadine. Alcaftadine is an antihistamine used for the prevention of itching of the eyes caused by allergies. Synonyms: 6,11-Dihydro-11-[1-(methyl-d3)-4-piperidinylidene]-5H-imidazo[2,1-b][3]benzazepine-3-carboxaldehyde. Grade: > 95%. Molecular formula: C19H18N3OD3. Mole weight: 311.41.
Alcaftadine 3-Carboxylic Acid
An analogue of Alcaftadine. Synonyms: 6,11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-Imidazo[2,1-b][3]benzazepine-3-carboxylic Acid. Grade: > 95%. CAS No. 147083-93-0. Molecular formula: C19H21N3O2. Mole weight: 323.4.
Alcaftadine N-Oxide
An analogue of Alcaftadine. Synonyms: 6,11-Dihydro-11-(1-methyl-1-oxido-4-piperidinylidene)-5H-imidazo[2,1-b][3]benzazepine-3-carboxaldehyde. Grade: > 95%. CAS No. 952649-75-1. Molecular formula: C19H21N3O2. Mole weight: 323.4.
Alclometasone Dipropionate
Alclomethasone-17,21-dipropionate is the dipropionate salt form of alclometasone, which is a synthetic corticosteroid with low to medium potency. It is used in dermatology as an anti-inflammatory, antiallergic, antipruritic, vasoconstrictive and antiproliferative agent. It is also used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. It was developed by Fougera Pharmaceuticals and has been listed. Uses: Alclomethasone-17,21-dipropionate is used in dermatology as an anti-inflammatory, antiallergic, antipruritic, vasoconstrictive and antiproliferative agent. it is also used for the relief of the inflammatory and pruritic manifestations of corticosteroid-re. Synonyms: Delonal; Vaderm; Aclosone; Alclomethasone-17,21-dipropionate; (7alpha,11beta,16alpha)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione. Grade: 95%. CAS No. 66734-13-2. Molecular formula: C28H37ClO7. Mole weight: 521.05.
Alclometasone Dipropionate Impurity 1
An Impurity of Alclometasone Dipropionate. Synonyms: 11β,17,21-Trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17,21-Dipropionate. Grade: > 95%. CAS No. 71868-53-6. Molecular formula: C28H38O7. Mole weight: 486.61.
Alcophosphamide
Alcophosphamide is a metabolite of the chemotherapeutic agent Cyclophosphamide. Synonyms: N,N-Bis(2-chloroethyl)phosphorodiamidic Acid 3-Hydroxypropyl Ester; NSC 153182; NSC 227248; O-(3-Hydroxypropyl) N,N-Bis(2-chloroethyl)phosphorodiamidate. Grade: > 95%. CAS No. 52336-54-6. Molecular formula: C7H17Cl2N2O3P. Mole weight: 279.1.
Alda 1
ALDH2 is the activator of both the wild-type ALDH2*1 and the asian E487K mutant ALDH2*2 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2). Uses: Activator of aldehyde dehydrogenase 2 (aldh2). Synonyms: Alda-1; Alda1; Alda 1. N-(1,3-Benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide. Grade: ≥98%. CAS No. 349438-38-6. Molecular formula: C15H11Cl2NO3. Mole weight: 324.16.
Aldehydo-D-glucose phthalazin-1-yl hydrazone
Aldehydo-D-glucose phthalazin-1-yl hydrazone is an extensively employed chemical compound in the biomedical industry, exhibiting potential for studying diverse ailments such as cancer and diabetes. Molecular formula: C14H18N4O5. Mole weight: 322.32.
Aldehydo-D-glucose Phthalazin-1-ylhydrazone
Aldehydo-D-glucose Phthalazin-1-ylhydrazone is a carbohydrate derivative of hydrazinophthalazine with anti-inflammatory activity. Synonyms: 1-(2-D-Glucopyranosylhydrazino)phthalazine; 1-Deoxy-1-[2-(1-phthalazinyl)hydrazinyl]-D-glucopyranose; D-Glucopyranose, 1-deoxy-1-[2-(1-phthalazinyl)hydrazinyl]-; Phthalazine, 1-(2-D-glucopyranosylhydrazino)-. Grade: 95%. CAS No. 881180-23-0. Molecular formula: C14H18N4O5. Mole weight: 322.32.
Aldicarb sulfone
Aldicarb Sulfone is an analog of Aldicarb detected in agricultural products as pesticide residue. Synonyms: Temik sulfone. Grade: >98%. CAS No. 1646-88-4. Molecular formula: C7H14N2O4S. Mole weight: 222.26.
Aldometanib
Aldometanib is an active aldolase inhibitor. It prevents FBP from binding to v-ATPase-associated aldolase and activates lysosomal AMPK. Aldometanib can be used for the research of metabolic homeostasis. Grade: >98.0%. CAS No. 2904601-67-6. Molecular formula: C27H43Cl2IN2. Mole weight: 593.46.
Aldose reductase-IN-1
Aldose reductase-IN-1, an aldose reductase inhibitor, could have potential biological usage in the study of breast cancer. IC50: 28.9 pM. Uses: Aldose reductase-in-1 is an aldose reductase inhibitor that could have potential biological usage in the study of breast cancer. Synonyms: Aldose reductase-IN-1; SCHEMBL359604; CS-5128; HY-18967; AT-001; CS 5128; HY 18967; AT 001; CS5128; HY18967; AT001. Grade: 98%. CAS No. 1355612-71-3. Molecular formula: C17H10F3N5O3S. Mole weight: 421.35.
Aldosterone
An adrenocortical steroid which exerts regulatory influence on metabolism of electrolytes and water. Synonyms: (11β)-11,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; 11β,21-Dihydroxypregn-4-ene-3,18,20-trione; 18-Formyl-11β,21-dihydroxy-4-pregnene-3,20-dione; 18-Oxocorticosterone; Electrocortin; Aldocortin; Aldocorten. Grade: > 95%. CAS No. 52-39-1. Molecular formula: C21H28O5. Mole weight: 360.45.
ALE-0540
ALE-0540 is a novel nonpeptidic molecule that inhibits the binding of NGF to tyrosine kinase (Trk) A or both p75 and TrkA, as well as signal transduction and biological responses mediated by TrkA receptors. Synonyms: 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-((2-hydroxyethyl)amino)-5-nitro-. Grade: >95.0%. CAS No. 234779-34-1. Molecular formula: C14H11N3O5. Mole weight: 301.26.
Alectinib
Alectinib, marketed as Alecensa, is an oral drug that blocks the activity of anaplastic lymphoma kinase (ALK) and is used to treat non-small-cell lung cancer (NSCLC). Alectinib has a low potential for interactions. While it is metabolised by the liver enzyme CYP3A4, and blockers of this enzyme accordingly increase its concentrations in the body, they also decrease concentrations of the active metabolite M4, resulting in only a small overall effect. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. Interactions via other CYP enzymes and transporter proteins cannot be excluded but are unlikely to be of clinical significance. Synonyms: CH-5424802; CH5424802; CH 5424802; AF-802; RG-7853; RO5424802. Grade: ≥95%. CAS No. 1256580-46-7. Molecular formula: C30H34N4O2. Mole weight: 482.62.
Aleglitazar
Aleglitazar is a potent dual agonist of peroxisome proliferator-activated receptor (PPAR) α/γ. Synonyms: RO-0728804; RO 0728804; RO0728804; RG-1439; R-1439; R 1439; R1439; Aleglitazar. Grade: >98%. CAS No. 475479-34-6. Molecular formula: C24H23NO5S. Mole weight: 437.51.
Alemtuzumab
Alemtuzumab is a monoclonal antibody directed against CD52. Alemtuzumab is indicated for the treatment of B-cell chronic lymphocytic leukemia and relapsing multiple sclerosis. Synonyms: Campath-IH. Grade: 95%. CAS No. 216503-57-0. Molecular formula: C6468H10066N1732O2005S40. Mole weight: 145.5 kDa.
Alendronate sodium trihydrate
Alendronate, a nitrogen-containing bisphosphonate, is a potent inhibitor of bone resorption used for the treatment and prevention of osteoporosis. Synonyms: G-704650, MK-217; G 704650, MK 217; G704650, MK217. Grade: >98%. CAS No. 121268-17-5. Molecular formula: C4H13NO7P2.3H2O.Na. Mole weight: 326.13.
Alendronic Acid Dimeric Anhydride
Alendronic Acid Dimeric Anhydride is an impurity of Alendronic Acid, which is a bone resorption inhibitor used to treat postmenopausal osteoporosis. Synonyms: Alendronic Acid Impurity 1; [3,6-Bis(3-aminopropyl)-2,5-dihydroxy-2,5-dioxido-1,4,2,5-dioxadiphosphinane-3,6-diyl]bis(phosphonic acid); Phosphonic acid, [3,6-bis(3-aminopropyl)-2,5-dihydroxy-2,5-dioxido-1,4,2,5-dioxadiphosphorinane-3,6-diyl]bis-; Alendronic Acid Dimeric Anhydride (Impurity). Grade: ≥95%. CAS No. 165043-20-9. Molecular formula: C8H22N2O12P4. Mole weight: 462.16.
Alendronic Acid Related Impurity 2
Alendronic Acid Related Impurity 2 is an impurity of Alendronic Acid, which is a bone resorption inhibitor used to treat postmenopausal osteoporosis. Synonyms: Cyclic Alendronic Acid; Alendronic Acid Related Impurity 2Q; 5-(3-Aminopropyl)-1,3,2,4,6-dioxatriphosphinane-4,5,6-triol 2,4,6-trioxide. Grade: ≥95%. CAS No. 165043-19-6. Molecular formula: C4H12NO8P3. Mole weight: 295.06.
aleplasinin
Aleplasinin is a selective and potent inhibitor of PAI-1 (Plasminogen activator inhibitor-1). It has been used in the treatment of Alzheimer's disease. Synonyms: PAZ-417; PAZ 417; PAZ417. Grade: 95%. CAS No. 481629-87-2. Molecular formula: C28H27NO3. Mole weight: 425.52.
Alexidine
Alexidine is a potent and selective protein tyrosine phosphatase localized to the mitochondrion 1(PTPMT1) inhibitor. Alexidine is an antimicrobial of the biguanide class. Synonyms: 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-; N,N''-Bis(2-ethylhexyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide; 1,1'-Hexamethylenebis[5-(2-ethylhexyl)biguanide]; 1,6-Bis(2-ethylhexylbiguanido)hexane; Bisguadine; Bisguanidine; QR 711; Sterwin 904; Win 21904. Grade: ≥95%. CAS No. 22573-93-9. Molecular formula: C26H56N10. Mole weight: 508.79.
Alexidine dihydrochloride
Alexidine dihydrochloride is a potent and selective protein tyrosine phosphatase localized to the mitochondrion 1(PTPMT1) inhibitor with IC50 value of 1.08 μM in vitro. It induces apoptosis in cancer cell lines with ED50 value of 1.8-2.6 μM. It is an alkyl bis(biguanide) antiseptic and has been used in mouthwashes to eliminate plaque forming microorganisms. It binds to lipopolysaccharide and lipoteichoic acid, and inhibits fungal phospholipase B with IC50 value of 250 nM. It stimulates increased insulin secretion by isolated rat pancreatic islets and displays antitcancer properties in FaDu cells. It has antibacterial, antiplaque properties against streptococcus mutans, actinomyces naesludii and actinomyces ciscosus. Synonyms: 2,4,11,13-Tetraazatetradecanediimidamide, N1,N14-bis(2-ethylhexyl)-3,12-diimino-, hydrochloride (1:2); 2,4,11,13-Tetraazatetradecanediimidamide, N,N''-bis(2-ethylhexyl)-3,12-diimino-, dihydrochloride; Biguanide, 1,1'-hexamethylenebis[5-(2-ethylhexyl)-, dihydrochloride; 1,6-Bis(2-ethylhexylbiguanido)hexane dihydrochloride; Alexidine hydrochloride; Hexamethylenebis(2-ethylhexyl)biguanide dihydrochloride. Grade: >98%. CAS No. 1715-30-6. Molecular formula: C26H58N10Cl2. Mole weight: 581.71.
A synthetic analog of Calcitiol (the hormonal form of vitamin D3), which shows identical potency with respect to stimulation of intestinal calcium absorption and bone mineral mobilization. Vitamin D source. Synonyms: 1-Hydroxycholecalciferol; Alfarol; EinsAlpha; Alpha-Calcidol; One-Alpha; (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol. Grade: >98%. CAS No. 41294-56-8. Molecular formula: C27H44O2. Mole weight: 400.65.
Alfacalcidol EP Impurity A
Alfacalcidol EP Impurity A is an impurity of Alfacalcidol, which is a non-selective VDR activator medication. Alfacalcidol improves mechanical bone strength and bone mass and suppresses osteoclastic bone resorption in vivo. Synonyms: 5,6-trans-alfacalcidol; trans-alfacalcidol; (5E,7E)-9,10-secocholesta- 5,7,10(19)-triene-1α,3β-diol. CAS No. 65445-14-9. Molecular formula: C27H44O2. Mole weight: 400.64.
Alfacalcidol EP Impurity B
Alfacalcidol EP Impurity B is an impurity of Alfacalcidol, which is a non-selective VDR activator medication. Alfacalcidol improves mechanical bone strength and bone mass and suppresses osteoclastic bone resorption in vivo. Synonyms: 1-Belta-Calcidol; (1β,3β,5Z,7E)- 9,10-Secocholesta-5,7,10(19)-triene-1,3-diol; 1β-Calcidol; (5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1β,3β-diol. CAS No. 63181-13-5. Molecular formula: C27H44O2. Mole weight: 400.65.
Alfacalcidol EP Impurity C
Alfacalcidol EP Impurity C is an impurity of Alfacalcidol, which is a non-selective VDR activator medication. Alfacalcidol improves mechanical bone strength and bone mass and suppresses osteoclastic bone resorption in vivo. Synonyms: Impurity C of Alfacalcidol; 6ξ-[(3S,5R)-3,5-Dihydroxy-2-methylcyclohex-1-en-1-yl]-17β-[(2R)-6-methylheptan-2-yl]-2-phenyl-2,5,10-triaza-4-nor-9ξ-estr-7-ene-1,3-dione; (6aR,7R,9aR)-11-((3S,5R)-3,5-Dihydroxy-2-methylcyclohex-1-en-1-yl)-6a-methyl-7-((R)-6-methylheptan-2-yl)-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione. Grade: >98%. CAS No. 82266-85-1. Molecular formula: C35H49N3O4. Mole weight: 575.78.
Alflutinib mesylate is a third-generation epidermal growth factor receptor (EGFR) inhibitor. Alflutinib has promising efficacy and acceptable safety profile for the treatment of EGFR T790M mutated NSCLC patients. Uses: Protein kinase inhibitors. Synonyms: Furmonertinib mesylate; AST2818 mesylate. CAS No. 2130958-55-1. Molecular formula: C29H35F3N8O5S. Mole weight: 664.7.
a-L-Fucose-1-phosphate
a-L-Fucose-1-phosphate is an indispensable biochemical compound prevalent in the biomedical industry orchestrating the research and development of glycans and glycoconjugates, paramount for regulating cell signaling and immune response dynamics. Molecular formula: C6H13O8P. Mole weight: 244.14.
a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt
A paramount constituent in the field of biomedicine, a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt serves as a pivotal factor in the production and analysis of enzymes related to carbohydrate metabolism. Its crucial role further extends to research on liver glycogen storage diseases, as well as in the treatment of select forms of malignancy. Indeed, this reagent proves itself to be a fundamental cornerstone in contemporary biomedical research. Synonyms: α-L-Fucose-1-phosphate (cyclohexylammonium salt); 6-Deoxy-α-L-Galactopyranose 1-(Dihydrogen Phosphate) Cyclohexanamine (1:2); α-L-Fucopyranose 1-(Dihydrogen Phosphate) Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl 1-Phosphate Di(cyclohexylammonium) Salt; α-L-Fucopyranosyl Phosphate Di(cyclohexylammonium) Salt. Grade: ≥98%. CAS No. 24333-03-7. Molecular formula: C6H13O8P.2C6H13N. Mole weight: 442.48.
Alfuzosin
Alfuzosin is a pharmaceutical drug of the alpha-1 blocker class. It works by relaxing the muscles in the prostate and bladder neck. It is used to treat benign prostatic hyperplasia (BPH). It offers an alternative to prostatectomy in patients who require surgery but are unfit for this treatment, and in patients requiring symptomatic relief while awaiting surgery. It is marketed in the United States by Sanofi Aventis under the brand name Uroxatral. It was approved by the FDA for treatment of BPH in June 2003. It has been approved the listing. Uses: Alfuzosin is used to treat benign prostatic hyperplasia (bph). Synonyms: Alfuzosina; Alfuzosine; Xatral; 2-Furancarboxamide,N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-; N-[3-[N-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-N-(methyl)amino]propyl]tetrahydrofuran-2-carboxamide; SL 77499; SL77499; SL-77499; Alfuzosinum. Grade: 99%. CAS No. 81403-80-7. Molecular formula: C19H27N5O4. Mole weight: 389.45.
Alfuzosin-d3
A labelled Alfuzosin. Alfuzosin is an alpha-1 adrenergic antagonist used for the treatment of benign prostatic hypertrophy. Synonyms: (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl]tetrahydrofuran-2-carboxamide-d3. Grade: > 95%. CAS No. 1006724-55-5. Molecular formula: C19H24N5O4D3. Mole weight: 392.48.
Alfuzosin HCl
Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH). Synonyms: (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino]propyl]tetrahydrofuran-2-carboxamide hydrochloride. Grade: >98%. CAS No. 81403-68-1. Molecular formula: C19H28ClN5O4. Mole weight: 425.91.
Alfuzosin Impurity 1
An impurity of Alfuzosin. Synonyms: 6,7-dimethoxy-N,N-dimethyl-quinazoline-2,4-diamine. Grade: > 95%. CAS No. 19216-68-3. Molecular formula: C12H16N4O2. Mole weight: 248.29.
Alfuzosin Impurity A
An impurity of Alfuzosin. Synonyms: Alfuzosin Tetradehydro Impurity ; Alfuzosin USP RC A. Grade: > 95%. CAS No. 98902-29-5. Molecular formula: C19H23N5O4. HCl. Mole weight: 421.88.
Alfuzosin Impurity C
An impurity of Alfuzosin. Synonyms: (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)amino]propyl]-N-methyltetrahydrofuran-2-carboxamide hydrochloride. Grade: > 95%. CAS No. 72104-34-8. Molecular formula: C19H27N5O4. Mole weight: 389.46.
Alfuzosin Impurity D
An impurity of Alfuzosin. Synonyms: Alfuzosin Aminopropyl Impurity ; Alfuzosin USP RC D. Grade: > 95%. CAS No. 76362-29-3. Molecular formula: C14H21N5O2. Mole weight: 291.36.