BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Sieber linker | Synonyms: 3-Hydroxy-xanthen-9-one; 3-Hydroxy-9H-xanthen-9-one; 3-Hydroxyxanthone; 9H-Xanthen-9-one, 3-hydroxy-; 3-oxidanylxanthen-9-one; KSC490E1T. Grades: ≥ 99% (HPLC). CAS No. 3722-51-8. Molecular formula: C13H8O3. Mole weight: 212.20. |  |
| Silver(?) trifluorometanesulfonate | Synonyms: AgOTf; CF3SO3Ag; Trifluoromethanesulfonic acid silver salt; Silver triflate; Silver(?) triflate. Grades: >98.0%(T). CAS No. 2923-28-6. Molecular formula: CF3SO3Ag. Mole weight: 256.94. | |
| Simocyclinone D4 | It is produced by the strain of Streptomyces antibioticus Tu 6040. It has moderate anti-gram-positive bacteria activity and has inhibitory effect on a variety of tumor cells. It inhibits HMO2, MCF7 and HEP G2 cells with GI50 (μmol/L) of 0.30, 5.6 and 8.5, respectively. Molecular formula: C46H43NO18. Mole weight: 897.83. | |
| Simocyclinone D8 | It is produced by the strain of Streptomyces antibioticus Tu 6040. It has moderate anti-gram-positive bacteria activity and has inhibitory effect on a variety of tumor cells. It inhibits HMO2, MCF7 and HEP G2 cells with GI50 (μmol/L) of 0.50, 0.95 and >50, respectively. Synonyms: 9-[4-O-Acetyl-3-O-[10-[(8-chloro-4,7-dihydroxy-2-oxo-2H-1-benzopyran-3-yl)amino]-1,10-dioxo-2,4,6,8-decatetraenyl]-2,6-dideoxy-beta-D-arabino-hexopyranosyl]-4a,5,6,12b-tetrahydro-4a,6,7,8,12b-pentahydroxy-3-methyl-6a,12a-epoxybenz[a]anthracene-1,12(4H,7H)-dione; (1R)-4-O-acetyl-1,5-anhydro-3-O-{(2E,4E,6E,8E)-10-[(8-chloro-4,7-dihydroxy-2-oxo-2H-chromen-3-yl)amino]-10-oxodeca-2,4,6,8-tetraenoyl}-2,6-dideoxy-1-[(4aR,6S,6aS,7S,12aS,12bR)-4a,6,7,8,12b-pentahydroxy-3-methyl-1,12-dioxo-1,4,4a,5,6,7,12,12b-octahydro-6a,12a-epoxytetraphen-9-yl]-D-arabino-hexitol. Grades: ≥95%. CAS No. 301845-97-6. Molecular formula: C46H42ClNO18. Mole weight: 932.27. | |
| Simvastatin | Simvastatin is a competitive inhibitor of HMG-CoA reductase with Ki of 0.1-0.2 nM. Synonyms: Nodinitib-1; Zocor; Synvinolin; MK-733; Sinvacor; MK 733; MK733. Grades: >98%. CAS No. 79902-63-9. Molecular formula: C25H38O5. Mole weight: 418.57. | |
| Siomycin | Siomycin is a peptide antibiotic that interacts with the 50S ribosomal subunit and inhibits binding of factor G and aminoacyl-tRNA. It exhibits antitumor activity against certain cancer cell lines. CAS No. 11017-43-9. Molecular formula: C64H88N16O22S4. Mole weight: 1561.73. | |
| Siomycin A | A macrocyclic antibiotic first isolated from S. sioyaensis with potent and selective antibacterial activity. It is a potent inhibitor of the oncogenic transcription factor, foxm1. It inhibits foxm1-induced cell growth on soft agar and selectively kills transformed but not normal cells in vitro. Synonyms: Mutabilycin; Sporangiomycin; 6741-21; NSC 285116; Antibiotic 6741-21; (1-L-valine)-[2-(2,3-didehydro-alanine)]-thiostrepton; Thiostrepton, 1-Valine-2-(2,3-didehydroalanine)-. Grades: >95% by HPLC. CAS No. 12656-09-6. Molecular formula: C71H81N19O18S5. Mole weight: 1648.84. | |
| Sirodesmin A | Sirodesmin A is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. TAN-1496 inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN-1496B; TAN 1496B. CAS No. 52988-50-8. Molecular formula: C20H26N2O8S2. Mole weight: 486.6. | |
| Sirodesmin B | It is produced by the strain of Sirodesmum diversum. It has antiviral effect. Synonyms: Spiro[furan-2 (3H), 9' (10'H)-[5, 11a] (iminomethano)[11aH]cyclopenta[4, 5]pyrrolo[2, 1-e][1, 2, 3, 4, 6]tetrathiazocine]-3, 6', 12' (5'H)-trione, 10'-(acetyloxy)-4,5,7'a,8',10'a,11'-hexahydro-10'ahydroxy-5'-(hydroxymethyl)-4,4,5,13'-tetramethyl-, (2R,5'R,7'aR,10'S,10'aS,11aR)-. CAS No. 52988-51-9. Molecular formula: C20H26N2O8S4. Mole weight: 550.69. | |
| Sirodesmin C | It is produced by the strain of Sirodesmum diversum. It has antiviral effect. Synonyms: Spiro[furan-2 (3H), 8' (9'H)-[4, 10a] (iminomethano)[10aH]cyclopenta[4, 5]pyrrolo[2, 1-d][1, 2, 3, 5]trithiazepine]-3, 5', 11' (4'H)-trione, 9'-(acetyloxy)hexahydro-9'a-hydroxy-4'-(hydroxymethyl)-4,4,5,12'-tetramethyl-, (2R,4'R,5R,6'aR,9'S,9'aS,10aR)-. CAS No. 52988-52-0. Molecular formula: C20H26N2O8S3. Mole weight: 518.62. | |
| Sirodesmin G | It is produced by the strain of Sirodesmum diversum. It has antiviral effect. CAS No. 64599-26-4. Molecular formula: C20H26N2O8S2. Mole weight: 486.56. | |
| Sisomicin | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa. It has no cross-resistance to kanamycin, but has cross-resistance to gentamycin. 50 mg/kg of Sisomicin has protective effect on mice infected with Rickettsia spinosa. Uses: Protein synthesis inhibitors. Synonyms: D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1?6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1?4)]-2-deoxy-; Antibiotic 6640; SCH 13475; Rickamicin; Sisomycin; Sissomicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1?6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1?4)]-2-deoxy-D-streptamine; Antibiotic 66-40; BactoCeaze; Ensamycin; Sch 13475; Siseptin. Grades: ≥98%. CAS No. 32385-11-8. Molecular formula: C19H37N5O7. Mole weight: 447.53. | |
| Sisomicin B | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: Sisomicin B; 6-O-[3-Deoxy-3-(methylamino)-α-D-xylopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40B; 6640B; D-Streptamine, O-3-deoxy-3-(methylamino)-alpha-D-xylopyranosyl-(1-6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-. CAS No. 53797-16-3. Molecular formula: C18H35N5O7. Mole weight: 433.50. | |
| Sisomicin D | It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: 6-O-[3-Deoxy-3-(methylamino)-β-L-arabinopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40D; 66-40D. CAS No. 53759-50-5. Molecular formula: C18H35N5O7. Mole weight: 433.50. | |
| Sisomicin Sulfate | Sisomicin Sulfate is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria. Uses: Protein synthesis inhibitors. Synonyms: D-Streptamine, 4-O-[(2S,3R)-3-amino-6-(aminomethyl-3,4-dihydro-2H-pyran-2-y1]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-, sulfate (salt); D-Streptamine, 4-O-[3-amino-6-(aminomethyl-3,4-dihydro-2H-pyran-2-y1]-2-deoxy-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-, (2S-cis)-, sulfate (salt). Grades: ≥95%. CAS No. 53776-71-9. Molecular formula: C19H37N5O7.xH2O4S. Mole weight: 447.52 (free base). | |
| SM 196A | SM 196A is a quinone antibiotic produced by Streptomyces sp. DMS 4769. It exhibits activity against gram-positive bacteria. Synonyms: SM-196A. CAS No. 135635-82-4. Molecular formula: C20H20O5. Mole weight: 340.4. | |
| SM 196B | SM 196B is a quinone antibiotic produced by Streptomyces sp. DMS 4769. Its activity against gram-positive bacteria is more potent than that of SM 196A. It also has anti-Herpes simplex virus activity. Synonyms: SM-196B. CAS No. 135635-83-5. Molecular formula: C20H18O5. Mole weight: 338.4. | |
| Small cardioactive peptide B | Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulates adenylate cyclase activity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0 μM, respectively. Synonyms: SCPB; Met-asn-tyr-leu-ala-phe-pro-arg-met-NH2. Grades: 98%. CAS No. 84746-43-0. Molecular formula: C52H80N14O11S2. Mole weight: 1141.41. | |
| S-Methyl-L-thiocitrulline acetate | S-Methyl-L-thiocitrulline is a potent nitric oxide synthase (NOS) inhibitor with selectivity for neuronal isoform versus eNOS and iNOS (Ki = 1.2, 11, and 40 nM for nNOS, eNOS, and iNOS, respectively). Synonyms: H-ThioCit(S-Me)-OH AcOH; L-Ornithine, N5-[imino(methylthio)methyl]-, acetate (1:1); L-Ornithine, N5-[imino(methylthio)methyl]-, monoacetate; (S)-2-Amino-5- ( (imino (methylthio)methyl)amino)pentanoic acid acetate. Grades: ≥95%. CAS No. 174063-92-4. Molecular formula: C9H19N3O4S. Mole weight: 265.33. | |
| SMTP-1 | SMTP-1 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C25H35NO5. Mole weight: 429.5. | |
| SMTP-2 | SMTP-2 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. The activity of SMTP-2 is weaker than SMTP-1. Molecular formula: C25H37NO7. Mole weight: 463.6. | |
| SMTP-3 | SMTP-3 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C26H35NO7. Mole weight: 473.6. | |
| SMTP-4 | SMTP-4 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C32H39NO6. Mole weight: 533.7. | |
| SMTP-5 | SMTP-5 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C29H41NO6. Mole weight: 499.6. | |
| SMTP-6 | SMTP-6 is a Staplabin homolog isolated from Stachybotrys microspora IFO30018. It enhanced the binding of Plasminogen to Fibrin. Molecular formula: C34H40N2O6. Mole weight: 572.7. | |
| SN-706 | SN-706 is an anthracycline antibiotic produced by Actinomadura reseoviolacea var miuraensis. It is active against gram-positive and gram-negative bacteria, as well as inhibits KB and HeLa cells with IC50 of 0.54 ng/mL. Synonyms: Antibiotic SN 706; SN 706. CAS No. 114511-93-2. Molecular formula: C36H45NO14. Mole weight: 715.7. | |
| SNA-4606-1 | SNA-4606-1 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 6.6 μmol/L. Molecular formula: C52H84O18. Mole weight: 997.2. | |
| SNA-4606-2 | SNA-4606-2 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor with IC50 of 8.7 μmol/L. Molecular formula: C53H86O18. Mole weight: 1011.24. | |
| SNA-4606-3 | SNA-4606-3 is an elaiophylin antibiotic isolated from Streptomyces sp. SNA-4606. It acts as a testosterone 5 alpha-reductase inhibitor. Molecular formula: C55H90O17. Mole weight: 1023.3. | |
| SNA-60-367 | SNA-60-367 are a group of aromatase inhibitors produced by soil bacterium, Bacillus sp. SNA-60-367. These inhibitors are a family of acylated decapeptides that differ from each other in terms of amino acid composition and the nature of the fatty acid side chain. | |
| SNA-8073B | SNA-8073A is an isotetracenone antibiotic isolated from the broth filtrate of Streptomyces sp. SNA-8073. It inhibited prolyl endopeptidase of Flavobacterium non-competitively with IC50 of 8.9 μmol/L. Synonyms: SNA-8073-B. Molecular formula: C20H16O5. Mole weight: 336.3. | |
| (S)-N-BOC-allylglycine | N-Boc-L-Allylglycine is a boc-protected allylglycine used in the preparation of arginine analogues including the natural amino acid enduracididine. Synonyms: (S)-2-[(tert-Butoxycarbonyl)amino]-4-pentenoic acid; BOC-L-Allylglycine; N-(tert-Butoxycarbonyl)-(S)-allylglycine. Grades: 97% (HPLC). CAS No. 90600-20-7. Molecular formula: C10H17NO4. Mole weight: 215.24. | |
| SNF-4435C | SNF-4435C is a nitrophenyl pyrone isolated from the culture broth of an actinomycete strain SNF4435. It is active against staphylococcus, mycobacteria, Candida albicans and Pyricularia oryzae. It shows a potent immunosuppressive activity in vitro and selectively suppresses B-cell proliferation induced by LPS versus T-cell proliferation induced by Con A. Synonyms: SNF4435C. Molecular formula: C28H31NO6. Mole weight: 477.5. | |
| SNF-4435D | SNF-4435D is a nitrophenyl pyrone isolated from the culture broth of an actinomycete strain SNF4435. It is active against staphylococcus, mycobacteria, Candida albicans and Pyricularia oryzae. It shows a potent immunosuppressive activity in vitro and selectively suppresses B-cell proliferation induced by LPS versus T-cell proliferation induced by Con A. Synonyms: SNF4435D. Molecular formula: C28H31NO6. Mole weight: 477.5. | |
| SNF-4794-11 | SNF-4794-11 is produced by Chaetomella sp. It inhibits α-glucosidase with IC50 of 0.09 μg/mL. Molecular formula: C33H58O8S. Mole weight: 614.9. | |
| SNF-4794-12 | SNF-4794-12 is produced by Chaetomella sp. It inhibits α-glucosidase with IC50 of 0.11 μg/mL. Molecular formula: C31H56O7S. Mole weight: 572.8. | |
| SNF-4794-7 | SNF-4794-7 is produced by Chaetomella sp. It inhibits α-glucosidase with IC50 of 0.18 μg/mL. CAS No. 89596-52-1. Molecular formula: C33H58O5. Mole weight: 534.8. | |
| SNF-4794-9 | SNF-4794-9 is produced by Chaetomella sp. It inhibits α-glucosidase with IC50 of 1.20 μg/mL. Molecular formula: C31H56O5. Mole weight: 508.77. | |
| SO-75R1 | SO-75R1 is a mutactimycin derivative produced by Nocardia brasiliensis. It inhibits gram-positive bacteria with MIC of 0.2-3.1 μg/mL, and inhibits L1210 cell with ED50 of 7.4 μg/mL. Synonyms: SO 75R1; SO-075R1. CAS No. 143458-82-6. Molecular formula: C29H34O11. Mole weight: 558.66. | |
| S-Octyl-L-cysteine | Synonyms: H-Cys(Octyl)-OH; H-Cys{(CH2)7-CH3}-OH. CAS No. 40379-80-4. Molecular formula: C11H23NO2S. Mole weight: 233.37. | |
| Somatorelin | Somatorelin is a releasing hormone of growth hormone (GH). Synonyms: GRF (human) Acetate; GHRF (1-44), human. Grades: 95%. CAS No. 83930-13-6. Molecular formula: C215H358N72O66S. Mole weight: 5039.63. | |
| Somatostatin-25 | Somatostatin-25 is a endogenous neuropeptide hormone that shows inhibitory activity against secretion of growth hormone. Synonyms: SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS; H-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH. CAS No. 76461-17-1. Molecular formula: C127H191N37O34S3. Mole weight: 2876.29. | |
| Somatostatin-28 (1-14) | Somatostatin-28 (1-14) has been used to produce antibodies selective for somatostatin-28 that do not bind to the C-terminal fragment somatostatin-14. Synonyms: H-SER-ALA-ASN-SER-ASN-PRO-ALA-MET-ALA-PRO-ARG-GLU-ARG-LYS-OH. CAS No. 79243-10-0. Molecular formula: C61H105N23O21S. Mole weight: 1528.71. | |
| Sorbistin A1 | It is an aminoglycoside antibiotic produced by the strain of Pseudomonas sorbicinii nov. sp. It has anti-gram-positive and negative bacteria effects. Sorbistin A1 has moderate antibacterial activity, but it is stronger than Sorbistin A2 and B. Sorbistin A1 has no anti-anaerobic effect, but it has anti-plant pathogenic bacteria effect. It has the property of resisting some aminoglycoside antibiotic passivase, so it has antibacterial effect on some strains resistant to aminoglycoside antibiotic. Synonyms: Antibiotic gla1; Antibiotic P 2563-I; Antibiotic BN 186A; Antibiotic P 2563P; Antibiotic BU 2183A; D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxopropyl)amino)-alpha-D-glucopyranosyl)-. CAS No. 60534-70-5. Molecular formula: C15H31N3O9. Mole weight: 397.42. | |
| Sorbistin A2 | It is an aminoglycoside antibiotic produced by the strain of Pseudomonas sorbicinii nov. sp. It has anti-gram-positive and negative bacteria effects. Sorbistin A1 has moderate antibacterial activity, but it is stronger than Sorbistin A2 and B. Synonyms: Antibiotic BU 2183B; 1,4-Diamino-1,4-dideoxy-3-O-(4-deoxy-4-butyrylamino-α-D-glucopyranosyl)-D-glucitol; Bu-2183A2; D-Glucitol, 1,4-diamino-1,4-dideoxy-3-O-(4-deoxy-4-((1-oxobutyl)amino)-alpha-D-glucopyranosyl)-. CAS No. 60534-69-2. Molecular formula: C16H33N3O9. Mole weight: 411.45. | |
| Sorbistin B | It is an aminoglycoside antibiotic produced by the strain of Pseudomonas sorbicinii nov. sp. It has anti-gram-positive and negative bacteria effects. Sorbistin A1 has moderate antibacterial activity, but it is stronger than Sorbistin A2 and B. Sorbistin B has no anti-anaerobic effect, but it has anti-plant pathogenic bacteria effect. Synonyms: Antibiotic BU 2183B; Antibiotic G1A2; Antibiotic P 2563-II; Antibiotic BN 186B; 3-O-(4-(Acetylamino)-4-deoxy-alpha-D-glucopyranosyl)-1,4-diamino-1,4-dideoxy-D-glucitol; D-Glucitol, 3-O-(4-(acetylamino)-4-deoxy-alpha-D-glucopyranosyl)-1,4-diamino-1,4-dideoxy-. CAS No. 60502-99-0. Molecular formula: C14H29N3O9. Mole weight: 383.40. | |
| Sordarin sodium salt | Sordarin is an antifungal metabolite produced by Sordaria areneosa. It inhibits protein synthesis via stabilizing the ribosome/EF2 complex. Synonyms: Sordarin sodium; Antibiotic SL-2266 sodium. Grades: ≥98%. CAS No. 463356-00-5. Molecular formula: C27H39O8Na. Mole weight: 514.58. | |
| Sorokinianin | Sorokinianin acts as an inhibitor of barley germination that exerts antifungal activity. Sorokinianin is a phytotoxic fungal metabolite isolated from the culture filtrates of the fungus Drechslera cynodontis. Synonyms: (3R,5S)-3-hydroxy-5-[(1S,2R,5R,7R,8S)-8-(hydroxymethyl)-5-methyl-6-methylidene-2-propan-2-yl-7-bicyclo[3.2.1]octanyl]oxolan-2-one; 2(3H)-Furanone, dihydro-3-hydroxy-5-[(1R,4R,5S,6R,8S)-8-(hydroxymethyl)-1-methyl-7-methylene-4-(1-methylethyl)bicyclo[3.2.1]oct-6-yl]-, (3R,5S)-; 2(3H)-Furanone, dihydro-3-hydroxy-5-[8-(hydroxymethyl)-1-methyl-7-methylene-4-(1-methylethyl)bicyclo[3.2.1]oct-6-yl]-, [1R-[1α, 4β, 5α, 6α(3R*, 5S*), 8S*]]-; (+)-Sorokinianin. Grades: 98.0%. CAS No. 162616-73-1. Molecular formula: C18H28O4. Mole weight: 308.41. | |
| Sorrentanone | It is produced by the strain of Penicillium chrysogenu SC 13887. It has weak to moderate effect against Gram-positive and Gram-negative bacteria. Synonyms: 2,5-Cyclohexadiene-1,4-dione, 2-hydroxy-3,6-dimethyl-5-[(2E,4E)-1-oxo-2,4-hexadien-1-yl]-; 2,5-Cyclohexadiene-1,4-dione, 2-hydroxy-3,6-dimethyl-5-(1-oxo-2,4-hexadienyl)-, (E,E)-. CAS No. 165337-76-8. Molecular formula: C14H14O4. Mole weight: 246.26. | |
| Sparfloxacin | Sparfloxacin is a fluoroquinolone antibiotic, shows broad and potent antibacterial activity. It can inhibit bacterial DNA gyrase, thereby inhibiting DNA replication and transcription. Uses: Antitubercular agents. Synonyms: Zagam; AT-4140. Grades: >98%. CAS No. 110871-86-8. Molecular formula: C19H22F2N4O3. Mole weight: 392.40. | |
| Sparoxomycin A1 | It is produced by the strain of Str. sparsogenes SN 2325. It is a novel mammalian cell proliferation effector that converts the transformed phenotype of Rous sarcoma virus-infected NRK cells to a normal phenotype. Synonyms: 2-Propenamide, N-[(1S)-1-(hydroxymethyl)-2-[[S(R)]-[[[S(S)]-methylsulfinyl]methyl]sulfinyl]-ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (2E)-. CAS No. 174390-01-3. Molecular formula: C13H19N3O6S2. Mole weight: 377.44. | |
| Sparoxomycin A2 | It is produced by the strain of Str. sparsogenes SN 2325. It is a novel mammalian cell proliferation effector that converts the transformed phenotype of Rous sarcoma virus-infected NRK cells to a normal phenotype. It has weak antimicrobial activity (such as Escherichia coli) but has no effect on staphylococcus aureus, candida albicans and staphylococcus grayi. Synonyms: 2-Propenamide, N-[(1S)-1-(hydroxymethyl)-2-[[S(R)]-[[[S(R)]-methylsulfinyl]methyl]sulfinyl]-ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (2E)-. CAS No. 174390-02-4. Molecular formula: C13H19N3O6S2. Mole weight: 377.44. | |
| Sparsomycin | It is an anti-tumor drug produced by the strain of Str. sparsogenes var. sparsogenes NRRL 2940, Str. cuspidosporus B-79. It has the effect of anti-bacterial and a few fungi. 0.05 μg/mL of Sparsomycin can inhibit the synthesis of 50% KB cell protein, it has the inhibitory effect on 11 kinds of experimental tumor, such as sarcoma-180 solid type, sarcoma-180 ascites type and Eschericz ascites carcinoma. Uses: Antibiotics, antineoplastic. Synonyms: Upjohn Antibiotic 155b1t; 2-Propenamide, N-(1-(hydroxymethyl)-2-(((methylthio)methyl)sulfinyl)ethyl)-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, (S-(E))-; 2-Propenamide, N-[1-(hydroxymethyl)-2-[[(methylthio)methyl]sulfinyl]ethyl]-3-(1,2,3,4-tetrahydro-6-methyl-2,4-dioxo-5-pyrimidinyl)-, [R-[R*,S*-(E)]]-; (+)-Sparsomycin; NSC 059729. Grades: >95%. CAS No. 1404-64-4. Molecular formula: C13H19N3O5S. Mole weight: 361.47. | |
| Spectinomycin | Spectinomycin is an aminoglycoside antibiotic isolated from Streptomyces spectabilis. Spectinomycin, a derivative of streptomyces spectabilis, has been found to be effective against gram-negative bacteria. Synonyms: Actinospectacin; Espectinomicina; Togamycin. Grades: ≥95%. CAS No. 1695-77-8. Molecular formula: C14H24N2O7. Mole weight: 332.35. | |
| Spectinomycin dihydrochloride pentahydrate | The dihydrochloride pentahydrate salt form of Spectinomycin, an aminoglycoside antibiotic isolated from Streptomyces spectabilis, has been found to be effective against gram-negative bacteria. Uses: Anti-bacterial agents. Synonyms: Spectam; Spectogard; Spectinomycin HCl pentahydrate; Togamycin dihydrochloride pentahydrate; [2R-(2α, 4aβ, 5aβ, 6β, 7β, 8β, 9α, 9aα, 10aβ)]-Decahydro-4a, 7, 9-trihydroxy-2-methyl-6, 8-bis(methylamino)-4H-pyrano[2, 3-b][1, 4]benzodioxin-4-one Dihydrochloride Pentahydrate; Actinospectacin dihydrochloride pentahydrate. Grades: 98%. CAS No. 22189-32-8. Molecular formula: C14H24N2O7.2HCl.5H2O. Mole weight: 495.35. | |
| Spectinomycin Sulfate Tetrahydrate | An aminocyclitol antibiotic similar to aminoglycosides. Synonyms: Actinospectacin tetrahydrate sulfate; 4H-Pyrano[2,3-b][1,4]benzodioxin-4-one, decahydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)-, (2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-, sulfate, hydrate (1:1:4). Grades: >95%. CAS No. 64058-48-6. Molecular formula: C14H24N2O7.H2O4S.4H2O. Mole weight: 502.49. | |
| Sperabillin A | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus, Streptococcus pyogenes and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 1.31, 8.13 and 67.2, respectively. Synonyms: L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadien-1-yl]amino]-; L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[(1-oxo-2,4-hexadienyl)amino]-, (E,Z)-; Antibiotic TAN 749A. CAS No. 111337-86-1. Molecular formula: C15H27N5O3. Mole weight: 325.41. | |
| Sperabillin B | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus, Streptococcus pyogenes and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 0.35, 8.84 and 27.3, respectively. Synonyms: D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-((1-oxo-2,4-hexadienyl)amino)-, (E,Z)-; D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-[[(2E,4Z)-1-oxo-2,4-hexadienyl]amino]-; Antibiotic TAN 749B. CAS No. 111337-85-0. Molecular formula: C16H29N5O3. Mole weight: 339.43. | |
| Sperabillin C | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 12.5 and 50, respectively. Synonyms: L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-; L-threo-Hexonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6-tetradeoxy-6-[(1-oxo-2,4-hexadienyl)amino]-, (E,E)-; Antibiotic TAN 749C. CAS No. 111337-84-9. Molecular formula: C15H27N5O3. Mole weight: 325.41. | |
| Sperabillin D | It is produced by the strain of Pseudomonas fluorescens YK-437. In vitro it has the effect of anti-pyomonas aeruginosa, alkali-producing faecal bacteria, acinetobacter calcium acetate and staphylococcus aureus. It also has antibacterial effect on Staphylococcus aureus and Pseudomonas aeruginosa resistant to methicillin, streptomycin, kanamycin, gentamicin, erythromycin, lincomycin, etc. It is used in mice infected with Staphylococcus aureus and E. coli O-111 with ED50 (mg/kg, subcutaneous) of 1.82 and 55.9, respectively. Synonyms: D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-[[(2E,4E)-1-oxo-2,4-hexadien-1-yl]amino]-; D-xylo-Heptonamide, 3-amino-N-(3-amino-3-iminopropyl)-2,3,4,6,7-pentadeoxy-6-((1-oxo-2,4-hexadienyl)amino)-, (E,E)-; Antibiotic TAN 749D. CAS No. 111465-40-8. Molecular formula: C16H29N5O3. Mole weight: 339.43. | |
| S-Phenyl-L-cysteine | . Uses: Inhibitor of enzyme. Synonyms: H-Cys(Phenyl)-OH. Grades: 98%. CAS No. 34317-61-8. Molecular formula: C11H23NO2S. Mole weight: 197.25. | |
| Spinamycin | It is an aromatic derivative of antibiotic produced by the strain of Str. albospinus M-750-G1. It has anti-mycobacterium and fungal effects, and the serum does not affect its effect on Cryptococcus yeast and psoriasis mold. It inhibits cell culture for Yoshida sarcoma with IC50 of 1.5 μg/mL. Mice can tolerate 125 mg/kg of Spinamycin intraperitoneal injection. Synonyms: Succinic acid, 2-(m-(1,3,5-hexatrienyl)phenyl)hydrazide; Succinic acid, mono(2-(m-1,3,5-hexatrienylphenyl)hydrazide); Butanedioic aid, mono(2-(3-(1,3,5-hexatrienyl)phenyl)hydrazide). CAS No. 25375-16-0. Molecular formula: C16H18N2O3. Mole weight: 286.33. | |
| Spinetoram J | It is the major component in the second generation spinosyn family of bio-insecticides marketed as spinetoram. It is a semi-synthetic compound prepared by selective ethylation and hydrogenation of spinosyn J, and it is also an insecticide. Synonyms: 3-Ethoxy-5,6-dihydro-spinosyn J; XDE-175-J; [2R-(2R*, 3aR*, 5aR*, 5bS*, 9S*, 13S*, 14R*, 16aS*, 16bR*)]-2-[(6-Deoxy-3-O-ethyl-2, 4-di-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R, 5S, 6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2, 3, 3a, 4, 5, 5a, 5b, 6, 9, 10, 11, 12, 13, 14, 16a, 16b-hexadecahydro-14-methyl-1H-as-Indaceno[3, 2-d]oxacyclododecin-7, 15-dione; (2R, 3aR, 5aR, 5bS, 9S, 13S, 14R, 16aS, 16bR)-2-[(6-Deoxy-3-O-ethyl-2, 4-di-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R, 5S, 6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2, 3, 3a, 4, 5, 5a, 5b, 6, 9, 10, 11, 12, 13, 14, 16a, 16b-hexadecahydro-14-methyl-1H-as-indaceno[3, 2-d]oxacyclododecin-7, 15-dione. Grades: >95% by HPLC. CAS No. 187166-40-1. Molecular formula: C42H69NO10. Mole weight: 748.00. | |
| Spinetoram L | It is the minor component in the second generation spinosyn family of bio-insecticides marketed as spinetoram. It is a semi-synthetic compound prepared by selective ethylation and hydrogenation of spinosyn L, and it is also an insecticide. Synonyms: 3-Ethoxy-spinosyn L; 3'-O-Ethylspinosyn L; XDE 175L; (2S, 3aR, 5aS, 5bS, 9S, 13S, 14R, 16aS, 16bS)-2-[(6-Deoxy-3-O-ethyl-2, 4-di-O-methyl-α-L-mannopyranosyl)oxy]-13-[[(2R, 5S, 6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-ethyl-2, 3, 3a, 5a, 5b, 6, 9, 10, 11, 12, 13, 14, 16a, 16b-tetradecahydro-4, 14-dimethyl-1H-as-indaceno[3, 2-d]oxacyclododecin-7, 15-dione. Grades: >95% by HPLC. CAS No. 187166-15-0. Molecular formula: C43H69NO10. Mole weight: 760.01. | |
| Spinosyn A 17-pseudoaglycone | It is an acid degradation product produced by selective hydrolysis of the more labile forosamine saccharide in the 17-position of spinosyn A. It has weak activity as an insecticide. Synonyms: A 83543A pseudoglycone; 2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone; (2R, 3aS, 5aR, 5bS, 9S, 13S, 14R, 16aS, 16bR)-9-ethyl-13-hydroxy-14-methyl-2-{[(3R, 4R, 5S, 6S)-3, 4, 5-trimethoxy-6-methyloxan-2-yl]oxy}-1H, 2H, 3H, 3aH, 5aH, 5bH, 6H, 7H, 9H, 10H, 11H, 12H, 13H, 14H, 15H, 16aH, 16bH-as-indaceno[3, 2-d]oxacyclododecane-7, 15-dione. Grades: >95% by HPLC. CAS No. 131929-68-5. Molecular formula: C33H50O9. Mole weight: 590.74. | |
| Spinosyn A aglycone | It is an acid degradation product produced by hydrolysis of both saccharide groups on spinosyn. It has only weak activity as an insecticide as the saccharides are considered essential for potent activity. Synonyms: (-)-spinosyn A aglycon; A 83543A Aglycon; (2R, 3aS, 5aR, 5bS, 9S, 13S, 14R, 16aS, 16bR)-9-ethyl-2, 13-dihydroxy-14-methyl-2, 3, 3a, 5a, 5b, 6, 9, 10, 11, 12, 13, 14, 16a, 16b-tetradecahydro-1H-as-indaceno[3, 2-d][1]oxacyclododecine-7, 15-dione. Grades: >95% by HPLC. CAS No. 149560-97-4. Molecular formula: C24H34O5. Mole weight: 402.52. | |
| Spirobenzofuran | It is produced by the strain of Acremonium sp. HKI 0230. It has moderate activity against gram-positive bacteria such as Bacillus subtilis with MIC of 25 μg/mL. It has no effect against gram-negative bacteria and fungi. Synonyms: 2,5-dihydroxy-2',2',6-trimethyl-2H-spiro[benzofuran-3,1'-cyclopentan]-4'-one. Molecular formula: C15H18O4. Mole weight: 262.30. | |
| Spirofungin A | It is produced by the strain of Str. violaceusniger Tü 4113. It has strong anti-yeast activity and moderate anti-filamentous fungus effect, but it has no effect against Gram-positive and Gram-negative bacteria. Synonyms: (2E,6E,8E)-(4S,5S)-10-[(2R,3S,6S,8R,9S)-8-((1E,3E)-4-Carboxy-3-methyl-buta-1,3-dienyl)-3,9-dimethyl-1,7-dioxa-spiro[5.5]undec-2-yl]-5-hydroxy-4,8-dimethyl-deca-2,6,8-trienoic acid; (-)-spirofungin A; 2,6,8-Decatrienoic acid, 10-[(2R,3S,6S,8R,9S)-8-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-3,9-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-5-hydroxy-4,8-dimethyl-, (2E,4S,5S,6E,8E)-. CAS No. 214143-44-9. Molecular formula: C29H42O7. Mole weight: 502.64. | |
| Spirofungin B | It is produced by the strain of Str. violaceusniger Tü 4113. It has strong anti-yeast activity and moderate anti-filamentous fungus effect, but it has no effect against Gram-positive and Gram-negative bacteria. Synonyms: (2E,6E,8E)-(4S,5S)-10-{(2R,3S,6R,8R,9S)-8-[(1E,3E)-4-carboxy-3-methyl-buta-1,3-dienyl]-3,9-dimethyl-1,7-dioxa-spiro(5.5)undec-2-yl}-5-hydroxy-4,8-dimethyl-deca-2,6,8-trienoic acid; 2,6,8-Decatrienoic acid, 10-[(2R,3S,6R,8R,9S)-8-[(1E,3E)-4-carboxy-3-methyl-1,3-butadienyl]-3,9-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-5-hydroxy-4,8-dimethyl-, (2E,4S,5S,6E,8E)-. CAS No. 214143-46-1. Molecular formula: C29H42O7. Mole weight: 502.64. | |
| Spirolaxine | Spirolaxine is a long-chain phthalide antibiotic produced by Sporotrichum laxum. It exhibits anti-Helicobacter pylori property. Synonyms: (+)-spirolaxine; Spirolaxin; (3R)-5-Hydroxy-7-methoxy-3-[5-[(2R,5R,7R)-2-methyl-1,6-dioxaspiro[4.5]dec-7-yl]pentyl]-1(3H)-isobenzofuranone. Grades: ≥95%. CAS No. 126382-01-2. Molecular formula: C23H32O6. Mole weight: 404.50. | |
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