BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| AG1295 | Tyrphostin AG 1295 is a selective inhibitor of PDGFR (platelet-derived growth factor receptor) protein tyrosine kinase (PDGF-receptor PTK)(IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 μM) in Swiss/3T3 cells. Synonyms: AG1295; AG 1295; AG 1295; NSC 380341; NSC380341; NSC-380341; Tyrphostin AG 1295. Grade: >98%. CAS No. 71897-07-9. Molecular formula: C16H14N2. Mole weight: 234.30. |  |
| AG 13958 | AG 13958 is a VEGFR tyrosine kinase inhibitor used for treatment of age-related macular degeneration (AMD). Synonyms: AG-13958; AG13958. CAS No. 319460-94-1. Molecular formula: C26H22FN7O. Mole weight: 467.50. | |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Synonyms: 2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile; Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-; CTK2G2659; AG1406; CTK2G 2659; AG 1406; CTK2G-2659; AG-1406. CAS No. 71308-34-4. Molecular formula: C16H18N2O. Mole weight: 254.333. | |
| AG-14361 | AG14361 is a PARP-1 inhibitor with Ki < 5 nmol/L. AG14361 is at least 1000-fold more potent than the benzamides. The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells. Synonyms: AG14361; AG-14361; AG 14361. Grade:>98%. CAS No. 328543-09-5. Molecular formula: C19H20N4O. Mole weight: 320.39. | |
| AG-1478 | AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-1478; AG-1478; AG1478; AG 1478. Grade: >98%. CAS No. 153436-53-4. Molecular formula: C16H14ClN3O2. Mole weight: 315.75. | |
| AG 1478 hydrochloride | The hydrochloride salt form of AG 1478, which has been found to be an epidermal growth factor receptor tyrosine kinase inhibitor. Synonyms: AG 1478 hydrochloride; AG1478 hydrochloride; AG-1478 hydrochloride; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride. Grade: ≥98% by HPLC. CAS No. 170449-18-0. Molecular formula: C16H14ClN3O2.HCl. Mole weight: 352.22. | |
| AG-1557 | AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG-1557; AG 1557; AG1557; N-(3-Iodophenyl)-6,7-dimethoxyquinazolin-4-amine. CAS No. 189290-58-2. Molecular formula: C16H14IN3O2. Mole weight: 407.211. | |
| AG-1557 hydrochloride | AG-1557 hydrochloride is a specific and ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG 1557 hydrochloride; AG1557 hydrochloride. Molecular formula: C16H15ClIN3O2. Mole weight: 443.66. | |
| AG-18 | AG 18 (10 μM) inhibits EGF-induced proliferation of GH3 cells. Synonyms: RG-50810; RG 50810; RG50810; Tyrphostin A23; AG-18; AG 18; AG18; TX 825; Tyrphostin A23; Tyrphostin AG-18. Grade: >98%. CAS No. 118409-57-7. Molecular formula: C10H6N2O2. Mole weight: 186.17. | |
| AG-1801 | AG-1801is a bio-active chemical for treatment of cell proliferative diseases. Synonyms: (E)-N-benzyl-2-cyano-3-(4-nitrophenyl)prop-2-enamide; UNII-WYN000A4MH; STK361572; AG-1801; AG1801; AG 1801. Grade: >98%. CAS No. 204010-55-9. Molecular formula: C17H13N3O3. Mole weight: 307.3. | |
| AG 1812 | This active molecular is a bio-active chemical and detailed information has not been published yet. Synonyms: AG 1812; AG1812; AG-1812; 2-[2-[[[1-(1H-benzimidazol-2-yl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-2-yl]methyldisulfanyl]methyl]-3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-1-yl]-1H-benzimidazole; dichloride. Grade: 98%. CAS No. 114559-57-8. Molecular formula: C32H28Cl2F6N6O2S2. Mole weight: 777.63. | |
| AG-1812 Free base | AG-1812 is a Lansoprazole disulfide active metabolite. Synonyms: AG-1812; AG 1812; AG1812; 2,2'-(dithiobis(methylene))bis(1-(1H-benzimidazol-2-yl)-3-methyl-4-(2,2,2-trifluoroethoxy)-Pyridinium; Lansoprazole disulfide active metabolite; UNII-6RI44GB0V9; AC1MIZB6; HE078804. Grade: 98%. CAS No. 700341-80-6. Molecular formula: C32H28F6N6O2S22+. Mole weight: 706.73. | |
| AG-183 | AG-183 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 0.8 μM in the human epidermoid carcinoma cell line A431. Synonyms: Tyrphostin 51; Tyrphostin AG 183. Grade: ≥98%. CAS No. 122520-90-5. Molecular formula: C13H8N4O3. Mole weight: 268.2. | |
| AG2000 Free Base | AG2000 Free Base is a bio-active chemical compound. It is also a lansoprazole sulfenamide active metabolite. Synonyms: AG-2000 Free Base; AG2000 Free Base; 4-Methyl-3-(2,2,2-trifluoroethoxy)-5H-pyrido[1',2':4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium; AG-2000 free base; Lansoprazole sulfenamide active metabolite. Grade: >98%. CAS No. 111712-15-3. Molecular formula: C16H13F3N3OS+. Mole weight: 352.35. | |
| AG 205 | AG 205 is a progesterone receptor membrane component 1 (Pgrmc1) ligand. It inhibits cell cycle progression and cell viability in cancer cell lines. It inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro. Synonyms: Cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone. Grade: ≥98%. CAS No. 442656-02-2. Molecular formula: C22H23ClN6OS. Mole weight: 454.98. | |
| AG-213 | AG-213 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 2.4 μM in the human epidermoid carcinoma cell line A431. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-213; Tyrphostin 47; (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide. Grade: ≥97%. CAS No. 122520-86-9. Molecular formula: C10H8N2O2S. Mole weight: 220.2. | |
| AG28262 | AG28262 is a bio-active chemical compound. It is a VEFG-r2 inhibitor and could cause an increase in serum ALT, due in part to both gene up-regulation. Synonyms: AG-28262; AG 28262; AG28262; Benzo(b)thiophene-3-carboxamide, N,2-dimethyl-6-((2-(1-methyl-1H-imidazol-2-yl)thieno(3,2-b)pyridin-7-yl)oxy)-; N,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy-1-benzothiophene-3-carboxamide. Grade: 98%. CAS No. 638216-89-4. Molecular formula: C22H18N4O2S2. Mole weight: 434.53. | |
| AG-348 sulfate hydrate | AG-348 sulfate hydrate is an orally active pyruvate kinase allosteric activator. Synonyms: Mitapivat hemisulfate sesquihydrate; AG-348 hemisulfate sesquihydrate; Pyrukynd; 8-Quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-, sulfate, hydrate (2:1:3). CAS No. 2151847-10-6. Molecular formula: C48H60N8O13S3. Mole weight: 1053.23. | |
| AG-370 | AG-370 is a selective inhibitor of PDGF receptor kinase with an IC50 value of 20 μM in human bone marrow fibroblasts. It displays comparatively weak inhibition of the EGF receptor (IC50 = 820 μM). Synonyms: NSC 651712; 2-pentenetricarbonitrile, 3-amino-4-(1h-indol-5-ylmethylene)-. Grade: ≥95%. CAS No. 134036-53-6. Molecular formula: C15H9N5. Mole weight: 259.3. | |
| AG-490 | Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Uses: Antineoplastic agents. Synonyms: Tyrphostin AG 490; AG-490; AG490. Grade: 0.98. CAS No. 133550-30-8. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| AG 494 | AG-494 is a EGFR (epidermal growth factor receptor) kinase inhibitor with IC50 value of 0.7 μM. It is selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively). AG-494 tyrphostin also can block Cdk2 activation. Synonyms: alpha-Cyano-(3,4-dihydroxy)-N-phenylcinnamide; Tyrphostin AG-494; Tyrphostin B48. Grade: 98%. CAS No. 139087-53-9. Molecular formula: C16H12N2O3. Mole weight: 280.28. | |
| AG-5507 | AG-5507 is a bio-active chemical howerver, its detailed information has not been published. Uses: A bio-active chemical. Synonyms: AG-5507; AG5507; AG 5507; UNII-I518B5DK9I; (7R,11S)-2-(3,5-dimethoxyphenyl)-12-(2-(3,5-dimethoxyphenyl)-2-oxoacetyl)-8,9,10,11-tetrahydro-2H-7,11-epiminopyrazino[1,2-a]azocine-3,6(4H,7H)-dione. Grade: ≥95%. CAS No. 294865-05-7. Molecular formula: C28H29N3O8. Mole weight: 535.19. | |
| AG 555 | AG 555 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50 = 0.7 μM) with 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Synonyms: AG 555; AG-555; AG555; (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide; AG 555; AG-555; alpha-cyano-(3,4-dihydroxy)-N-(3-phenylpropyl)cinnamide; N-(3'-Phenylpropyl)-3,4-dihydroxybenzylidenecyanoacetamide; N-(3-phenylpropyl)-3,4-dihydroxybenzylidene cyanoacetamide; tyrphostin AG 555; tyrphostin AG-555; tyrphostin B46. Grade: ≥98% (HPLC). CAS No. 133550-34-2. Molecular formula: C19H18N2O3. Mole weight: 322.36. | |
| AG 556 | AG 556, a dihydroxyphen derivative, has been found to be a EGFR kinase inhibitor that could probably be effective in the study of myocardial infarct and hemodynamic deterioration. IC50: 1.1 μM. Synonyms: AG556; AG-556; CHEMBL440298; (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide. Grade: 98%. CAS No. 133550-41-1. Molecular formula: C20H20N2O3. Mole weight: 336.38. | |
| AG-636 | AG-636 is an orally available inhibitor of dihydroorotate dehydrogenase (DHODH) with strong in vitro and in vivo anti-tumor activity. AG-636 has benn identified as a drug candidate for the treatment of patients with advanced lymphoma. Synonyms: AG 636; AG636. CAS No. 1623416-31-8. Molecular formula: C21H17N3O2. Mole weight: 343.38. | |
| AG-7404 | AG-7404 is an inhibitor of picornaviral 3C protease against a large panel of programmatically important poliovirus strains. AG-7404 was fully active against all V-073-resistant variants with EC50 values ranging from 0.218 to 0.819 μM. Synonyms: AG-7404; 343565-99-1; VQ1AN3OO42; imocitrelvir; UNII-VQ1AN3OO42; V-7404; AG7404; AG 7404; ethyl (E,4S)-4-[[(2S)-2-[3-[(5-methyl-1,2-oxazole-3-carbonyl)amino]-2-oxopyridin-1-yl]pent-4-ynoyl]amino]-5-[(3S)-2-oxopyrrolidin-3-yl]pent-2-enoate; (S,E)-ethyl 4-((S)-2-(3-(5-methylisoxazole-3-carboxamido)-2-oxopyridin-1(2H)-yl)pent-4-ynamido)-5-((S)-2-oxopyrrolidin-3-yl)pent-2-enoate; imocitrelvir [INN]; C. Grade: 98% by HPLC. CAS No. 343565-99-1. Molecular formula: C12H11FN5Na4O12P3. Mole weight: 621.12. | |
| AG-82 | AG-82 is an inhibitor of epidermal growth factor receptor kinase with an IC50 value of 3 μM in the human epidermoid carcinoma cell line A431. Uses: Antineoplastic agents. Synonyms: NSC 676484; RG-50875; Tyrphostin 25; Tyrphostin AG-82. Grade: ≥95%. CAS No. 118409-58-8. Molecular formula: C10H6N2O3. Mole weight: 202.2. | |
| AG 825 | AG 825, a selective ErbB2 (Neu) inhibitor, could probably show activities in triggerring p38 MAP kinase-dependent apoptosis at some extent. Synonyms: AG 825; AG825; AG-825; (E)-3-[3-[2-Benzothiazolythio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide. Grade: ≥95% by HPLC. CAS No. 149092-50-2. Molecular formula: C19H15N3O3S2. Mole weight: 397.47. | |
| AG-879 | AG-879, a tyrphostin compound, is a dual EGFR/HER2 inhibitor that was administered together with androgen withdrawal therapy. It inhibits nerve growth factor (NGF)-dependent TrkA tyrosine phosphorylation in PC-12 cells (IC50 = ~40 μM), HER2-ErbB2 kinase in several breast and ovarian cancer cell lines (IC50 = ~0.5 μM), and the VEGF receptor FLK1 (IC50 = ~1 μM). Synonyms: α-Cyano-(3,5-di-t-butyl-4-hydroxy)thiocinnamide. CAS No. 148741-30-4. Molecular formula: C18H24N2OS. Mole weight: 316.5. | |
| AG957 | AG957 is commonly used to study Bcr-Abl signaling in the CML K562 cell line. AG957 is also used to study signaling through c-Abl. Synonyms: NSC 654705; Tyrphostin AG957; Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester. Grade: ≥95%. CAS No. 140674-76-6. Molecular formula: C15H15NO4. Mole weight: 273.3. | |
| AG 99 | AG 99, an EGF receptor tyrosine kinase inhibitor, has been found to show activities in diagnosis, prevention and treatment of cancer. Synonyms: AG 99; AG-99; AG99; (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenamide. Grade: ≥99% by HPLC. CAS No. 122520-85-8. Molecular formula: C10H8N2O3. Mole weight: 204.18. | |
| Aganepag | Aganepag is a prostaglandin E2 receptor agonist with an EC50 of 0.19 nM. Synonyms: AGN 210937; AGN-210937; 5-(3-((s)-1-(4-((s)-1-hydroxyhexyl)phenyl)-5-oxopyrrolidin-2-yl)propyl)thiophene-2-carboxylic acid. CAS No. 910562-18-4. Molecular formula: C24H31NO4S. Mole weight: 429.57. | |
| Aganepag isopropyl | Aganepag isopropyl is an EP2 agonist. Aganepag isopropyl is used for treatment of Glaucoma. Synonyms: AGN-210961; AGN 210961; AGN210961. CAS No. 910562-20-8. Molecular formula: C27H37NO4S. Mole weight: 471.66. | |
| Agar | Agar is used as an emulsifier, stabilizer, suspending agent, sustained-release agent, tablet binder, thickener and viscosity-increasing agent. Synonyms: Agar-agar; Agar-agar flake; Agar-agar gum; Bengal gelatin; Bengal gum; Bengal isinglass; Ceylon isinglass; Chinese isinglass; E406; Gelose; Japan agar; Japan isinglass; layor carang; Gelose; Azazoon; Agargel; Agaron gel; Bacto-agar; Bengal isinglass; Ceylon isinglass; Chinese isinglass; Kantenmatsu; Karikorikan; Phytagar; Sabouraud dextrose agar. CAS No. 9002-18-0. Molecular formula: (C12H18O9)n. | |
| Agarobiose | Agarobiose is a naturally occurring disaccharide found in the cell walls of certain types of red algae, commonly used as a substance for microbial culture media, and it shows promise for the treatment of certain diseases such as cancer and obesity due to its anti-inflammatory properties. Synonyms: 4-O-b-D-Galactopyranosyl-3,6-anhydro-L-galactose; 3,6-Anhydro-4-O-β-D-galactopyranosyl-L-galactose; Galactose, 3,6-anhydro-4-O-β-D-galactopyranosyl-, L-. CAS No. 5627-25-8. Molecular formula: C12H20O10. Mole weight: 324.28. | |
| Agaroctaitol | Agaroctaitol is a cutting-edge compound, standing as a prominent solution for studying inflammatory bowel diseases, namely Crohn's disease and ulcerative colitis. This compound serves as an impressive inhibitor of pro-inflammatory cytokines. Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol; [O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)]3-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol. Grade: ≥97% by GPC. CAS No. 137042-78-5. Molecular formula: C48H76O37. Mole weight: 1245.09. | |
| Agarodecaitol | Agarodecaitol is an intriguing molecular entity, exclusively obtained from the intricate breakdown of agarose is an intricate and structurally captivating polysaccharide sourced from marine algea. Notably, this bioactive constituent has demonstrated immense promise as a potent anti-inflammatory and antioxidant entity within a diverse array of biomedical research areas. Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol; [O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)]4-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol. Grade: ≥96% by GPC. CAS No. 137042-79-6. Molecular formula: C60H94O46. Mole weight: 1551.36. | |
| Agarodecaose | Agarodecaose is a biomedical product commonly used in the treatment of various gastrointestinal disorders. Derived from agar, it possesses anti-inflammatory properties that alleviate symptoms associated with irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-β-D-galactopyranose. Molecular formula: C66H102O51. Mole weight: 1711.49. | |
| Agarodiitol | Agarodiitol is a compound commonly found in the medicinal mushroom Agaricus blazei studied for its potential anti-tumor and immune-modulating properties. Molecular formula: C12H22O10. Mole weight: 326.30. | |
| Agarododecaitol | Agarododecaitol is a remarkable biomedical constituent, used for studying diabetes mellitus. Its unparalleled potential lies within the realms of controlling glycemic indices and augmenting the responsiveness of insulin. Synonyms: [O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)]5-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol. Grade: ≥95% by GPC. CAS No. 945616-74-0. Molecular formula: C72H112O55. Mole weight: 1857.62. | |
| Agaroheptaose | Agaroheptaose is a remarkable biomedical compound, manifesting capability to impede neoplastic cells expansion and curtail metastasis. Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-β-D-galactopyranose; (2R,3R,4S,5S,6R)-4-(((1S,3S,4S,5S,8R)-8-(((2S,3R,4S,5S,6R)-4-(((1S,3S,4S,5S,8R)-8-(((2S,3R,4S,5S,6R)-3,5-Dihydroxy-4-(((1S,3S,4S,5S,8R)-4-hydroxy-8-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2,6-dioxabicyclo[3.2.1]octan-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,5-triol. Grade: 97%. CAS No. 852690-25-6. Molecular formula: C42H66O33. Mole weight: 1098.95. | |
| Agarohexaitol | Agarohexaitol is a biomedical compound derived from agar and used in the research of gastrointestinal disorders. It exhibiting potent anti-inflammatory and antioxidant activities. Synonyms: [O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)]2-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol. Grade: ≥98% by GPC. Molecular formula: C36H58O28. Mole weight: 938.83. | |
| Agarononaose | Agarononaose is an intriguing bioactive compound with an astounding propensity for research of a myriad of ailments, spanning from the realm of cancer and diabetes to inflammation. Grade: ≥96% by GPC. | |
| Agaropentadecaose | Agaropentadecaose is a molecular carbohydrate originating from agarose, a seaweed-based polysaccharide, holding significant promise in research of antivirals, such as HIV/AIDS. Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-β-D-galactopyranose. Grade: ≥95% by GPC. Molecular formula: C90H138O79. Mole weight: 2324.01. | |
| Agaropentaose | Agaropentaose is a remarkable and scientifically prebiotic compound, origining from the remarkable agar, an exquisite natural polysaccharide captivatingly sourced from marine algae. Synonyms: 2,6-Dioxabicyclo[3.2.1]octane,β-D-galactopyranose deriv; O-beta-D-Galactopyranosyl-(1-4)-O-3,6-anhydro-alpha-L-galactopyranosyl-(1-3)-O-beta-D-galactopyranosyl-(1-4)-O-3,6-anhydro-alpha-L-galactopyranosyl-(1-3)-beta-D-galactopyranose. Grade: 98%. CAS No. 155015-99-9. Molecular formula: C30H48O24. Mole weight: 792.69. | |
| Agarose | Agarose is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Synonyms: 3,6-Anhydro-a-L-galacto-b-D-galactan; Sepharose; 3,6-Anhydro-α-L-galacto-β-D-galactan; A 0169; Agaoligo; Agarose 1600; Agarose E; Agarose III; Agarose S; Aqua-S; Certified PCR; D 1LE; FastLane agarose; Focurose 6HP; Indubiose A 4; NuSieve GTG; Odigose; QA-Agarose; Rapid Run; Reacti-Gel; S 180. Grade: ≥95%. CAS No. 9012-36-6. | |
| Agarotetradecaitol | Agarotetradecaitol is a groundbreaking biomedical compound with unique mechanism thwarting the propagation and elongation of cancerous cells, used for research of an array of malignancies encompassing mammary, pulmonary and colonic carcinomas. Synonyms: [O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)]6-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol. Grade: ≥95% by GPC. CAS No. 945616-76-2. Molecular formula: C84H130O64. Mole weight: 2163.89. | |
| Agarotetraitol | Agarotetraitol is an illustrious compound renowned for its unprecedented antiviral prowess, unveiling its paramount role in impeding viral replication. Synonyms: Agarotetritol; O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→3)-1,4-anhydro-D-galactitol. Grade: ≥98% by GPC. CAS No. 63737-22-4. Molecular formula: C24H40O19. Mole weight: 632.56. | |
| Agarotetraose | Agarotetraose. Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-3,6-anhydro-L-galactose. CAS No. 69178-33-2. Molecular formula: C24H38O19. Mole weight: 630.55. | |
| Agarotridecaose | Agarotridecaose is an intricate carbohydrate molecule obtained from the algal polysaccharide agar. With its application as a molecular probe in the biomedical landscape, it is used to unravel the intricate dance between biomolecules such as proteins and carbohydrates alike. Synonyms: O-β-D-Galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-O-3,6-anhydro-α-L-galactopyranosyl-(1→3)-β-D-galactopyranose. Grade: ≥95% by GPC. Molecular formula: C78H120O60. Mole weight: 2017.75. | |
| Agarotriose | Agarotriose is a powerful compound used in the research of gastrointestinal health. This innovative compound targets the research of digestive disorders, such as irritable bowel syndrome (IBS) and dysbiosis. Synonyms: O-beta-D-Galactopyranosyl-(1-4)-O-3,6-anhydro-alpha-L-galactopyranosyl-(1-3)-beta-D-galactopyranose. Grade: 98%. CAS No. 155015-96-6. Molecular formula: C18H30O15. Mole weight: 486.42. | |
| Agaroundecaose | Agaroundecaose is a remarkable biomedical compound used for studying malignancies, encompassing the unforgiving realms of breast, lung and colon cancer. This extraordinary research exerts its profound impact by skillfully thwarting the insidious growth of tumor cells while simultaneously orchestrating apoptosis. Molecular formula: C66H102O5. Mole weight: 975.51. | |
| Agatolimod sodium | Agatolimod sodium selectively targets Toll-like receptor 9 (TLR9). It has potential antineoplastic and immunostimulatory activity and is used as an anticancer adjuvant and immunostimulant. Synonyms: DNA, d(P-thio)(T-C-G-T-C-G-T-T-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T), tricosasodium salt; ODN 7909; AS 07A; CpG 2006 sodium salt; CpG ODN 7909; CpG 7909; PF-3512676; ProMune; ProMune CpG 7909. Grade: 98%. CAS No. 541547-35-7. Molecular formula: C238H291N75Na23O127P23S23. Mole weight: 8212.89. | |
| AGB1 | AGB1, a potent, fast and highly selective bump-and-hole (B&H)-PROTAC degrader for BromoTag, exhibits degradation of Ab:Brd4BD2 L387A and Ab: BromoTag-Brd2 with pDC50s of 7.8 and 7.9, respectively. It has binary affinity for VHL (Kd = 125 nM), and has good pharmacokinetic characteristics in mice with a DC50 (6h) of ~13 nM. Synonyms: (S)-13-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidine-1-carbonyl)-14,14-dimethyl-11-oxo-3,6,9-trioxa-12-azapentadecyl (R)-2-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoate. Grade: ≥95%. CAS No. 2776190-62-4. Molecular formula: C51H63ClN8O9S2. Mole weight: 1031.68. | |
| AGI-5198 | AGI-5198 is the first highly potent and selective inhibitor of IDH1 R132H/R132C mutants with IC50 of 0.07 μM/0.16 μM. Synonyms: AGI5198; AGI-5198; AGI 5198; IDHC35; IDH-C35; IDH C35. Grade: >98%. CAS No. 1355326-35-0. Molecular formula: C27H31FN4O2. Mole weight: 462.56. | |
| AGI-6780 | AGI-6780 is an IDH2 inhibitor that potently and selectively inhibits the tumor-associated mutant IDH2/R140Q with IC50 of 23±1.7 nM. AGI-6780 is less potent against IDH2WT with IC50of 190±8.1 nM. Synonyms: AGI6780; AGI 6780; AGI-6780. CAS No. 1432660-47-3. Molecular formula: C21H18F3N3O3S2. Mole weight: 481.508. | |
| Agistatin E | Agistatin E is a novel pyranacetal isolated from fungus FH-A 6239. It has been used as a cholesterol biosynthesis inhibitor. Mycotoxin. Synonyms: Agistatin E; 144096-48-0; (1S,3S,6R,7R,8R)-6-ethyl-3,8-dihydroxy-2,11-dioxatricyclo[5.3.1.03,8]undecan-9-one; HY-N10232; CS-0109121; J-007915. Grade: ≥98%. CAS No. 144096-48-0. Molecular formula: C11H16O5. Mole weight: 228.24. | |
| AGK2 | AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. Synonyms: AGK-2; AGK 2; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide. Grade: >98%. CAS No. 304896-28-4. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.27. | |
| AGK7 | AGK2 is a cell-permeable, selective inhibitor of SIRT2 (IC50 = 3.5 μM) that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. AGK7 is an inactive control to be used in experiments with AGK2. Synonyms: SIRT2 Inhibitor (Inactive Control); 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-8-ylprop-2-enamide. Grade: ≥95%. CAS No. 304896-21-7. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.3. | |
| AGL 2263 | AGL 2263 is an inhibitor of the insulin-like growth factor 1 receptor (IGF-1R; IC50 = 0.43 μM). Synonyms: (E)-2-(3,4-dihydroxybenzoyl)-3-(2-oxo-3H-1,3-benzoxazol-5-yl)prop-2-enenitrile. Grade: ≥98%. CAS No. 638213-98-6. Molecular formula: C17H10N2O5. Mole weight: 322.3. | |
| Aglafoline | Aglafoline, isolated from Aglaia elliptifolia Merr, is a selective PAF-induced platelet aggregation inhibitor. And studies have shown that because aglafoline blocked the high-K+-induced contraction of rat thoracic aorta, it may also possess Ca+- channel b. Synonyms: methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate Aglafoline Methyl rocaglate AGLAFOLIN CHEBI:65374 CMLDBU00002646 143901-35-3 methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydr. CAS No. 143901-35-3. Molecular formula: C28H28O8. Mole weight: 492.52. | |
| a-Glucametacin | a-Glucametacin, the acclaimed anti-inflammatory wonder, showcases its unparalleled efficacy in combating a myriad of inflammatory afflictions, notably arthritis, while effectively tackling postoperative discomfort. By impeding the production of prostaglandins and leukotrienes, this remarkable drug alleviates pain and curtails inflammation. Synonyms: 2-[[[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-a-D-glucopyranose; a-Glucametacine; a-Glucamethacin; α-D-Glucopyranose, 2-[[[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-. CAS No. 871014-84-5. Molecular formula: C25H27ClN2O8. Mole weight: 518.94. | |
| agmatidine | Agmatidine is a compound, finding application in the biomedical realm for studying assorted ailments comprising cancer and inflammation. Its exceptional attributes encompass anti-inflammatory and anti-carcinogenic effects, rendering it a propitious contender for pharmaceutical development. Synonyms: Agmatidine; agm(2)C; N-(4-carbamimidamidobutyl)-4-imino-1-(beta-D-ribofuranosyl)-1,4-dihydropyrimidin-2-amine; 1221169-70-5; RD252EB5W3; CHEBI:64329; DTXSID701029783; Q4692957; N-(4-Carbamimidamidobutyl)-4-imino-1-(beta-D-ribofuranosyl)-1,4-dihydro-2-pyrimidinamine; GUANIDINE, N-(4-((1,4-DIHYDRO-4-IMINO-1-.BETA.-D-RIBOFURANOSYL-2-PYRIMIDINYL)AMINO)BUTYL)-; N-(4-((1,4-DIHYDRO-4-IMINO-1-.BETA.-D-RIBOFURANOSYL-2-PYRIMIDINYL)AMINO)BUTYL)GUANIDINE. Molecular formula: C14H22N7O4. Mole weight: 356.4. | |
| AGN 192403 hydrochloride | The hydrochloride salt form of AGN 192403, which has been found to show high affinity to imidazoline I1 receptor. Synonyms: AGN-192403 hydrochloride, AGN192403 hydrochloride, AGN 192403 hydrochloride, AGN-192403 HCl; (±)-2-endo-Amino-3-exo-isopropylbicyclo[2.2.1]heptane hydrochloride. Grade: ≥95% by HPLC. CAS No. 1021868-90-5. Molecular formula: C10H19N.HCl. Mole weight: 189.73. | |
| AGN 192836 | AGN 192836 is a potent and selective α2 adrenergic agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. Synonyms: (1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine; 2-[[(5-Methyl-2,3-dihydro-1,4-benzodioxin)-6-yl]amino]-1H-imidazole. CAS No. 171102-29-7. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
| AGN 193109 | AGN 193109 has been found to be a pan-retinoic acid receptor (RAR) antagonist. Synonyms: AGN 193109; AGN193109; AGN-193109; 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid. Grade: ≥97% by HPLC. CAS No. 171746-21-7. Molecular formula: C28H24O2. Mole weight: 392.49. | |
| AGN 193109 Sodium Salt | AGN 193109 is a potent antagonist of retinoic acid receptors (RARs, Kd = 2, 2, and 3 nM for RARα, β, and γ, respectively). Synonyms: 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-benzoic acid monosodium salt; CD 3106 Sodium Salt; Benzoic acid, 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-, sodium salt (1:1); sodium 4-((5,5-dimethyl-8-(p-tolyl)-5,6-dihydronaphthalen-2-yl)ethynyl)benzoate. Grade: 95%. Molecular formula: C28H23NaO2. Mole weight: 414.47. | |
| AGN 194078 | AGN 194078, is a selective RARα agonist with a Kd and EC50 of 3 and 112 nM, respectively. Synonyms: AGN-194078. CAS No. 321995-62-4. Molecular formula: C22H23F2NO4. Mole weight: 403.42. | |
| AGN 194310 | A high affinity pan-RAR antagonist (AGN194310, K(d) for binding to RARs=2-5 nM) inhibited colony formation (by 50%) by all three lines at 16-34 nM, and led to a transient accumulation of flask-cultured cells in G1 followed by apoptosis. AGN194310 is 12-22 fold more potent than all-trans retinoic acid (ATRA) against cell lines and also more potent in inhibiting the growth of primary prostate carcinoma cells. The administration of all-trans retinoic acid to VAD mice resulted in a transient reduction in NF-kappaB activity and, conversely, a single dose of the RAR-pan-antagonist, AGN 194310, administered to control mice, led to a marked, transient induction of whole-body luminescence. Mice were treated with AGN194310, a synthetic retinoid that antagonises the physiological function of the three RAR isotypes (alpha, beta, gamma) but does not interact with RXRs. Analyses of the granulocytic lineage using Gr-1, c-Kit and CD11b antibodies, demonstrated that granulocyte numbers were strikingly increased across haemopoietic compartments in all AGN194310-treated mice. A significant increase in the frequency of progenitor cells containing granulocytes was observed in the bone marrow of mice following treatment with AGN194310. Synonyms: AGN194310; AGN-194310; VTP194310; VTP 194310; VTP-194310. Grade: >98%. CAS No. 229961-45-9. Molecular formula: C28H24O2S. Mole weight: 424.55. | |
| AGN 195183 | RX-195183 is an RARα agonist (Kd=3 nM) with potential antineoplastic activity, modulating the transcription of genes responsible for cell differentiation and proliferation. Uses: Rarα agonist. Synonyms: IRX5183; IRX-5183; IRX 5183; NRX195183; NRX-195183; NRX 195183; VTP-195183; VTP195183; VTP 195183; AGN-195183; AGN195183; AGN195183.; 4-[(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]-2,6-difluorobenzoic acid. Grade: ≥98%. CAS No. 367273-07-2. Molecular formula: C22H22ClF2NO4. Mole weight: 437.87. | |
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