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Spiromesifen Metabolite M01
It is the metabolite of Spiromesifen, which is a spirocyclic tetronic acid, environmentally friendly and novel structural pesticide. Synonyms: 1-Oxaspiro[4.4]non-3-en-2-one, 4-hydroxy-3-(2,4,6-trimethylphenyl)-; 3-Mesityl-2-oxo-1-oxaspiro(4.4)non-3-en-4-ol; Spiromesifen-alcohol; 4-Hydroxy-3-mesityl-1-oxaspiro(4.4)non-3-en-2-one. Grades: ≥90%. CAS No. 148476-30-6. Molecular formula: C17H20O3. Mole weight: 272.34.
Spiro-Oxanthromicin A
Spiro-Oxanthromicin A is a polyketide first isolated from a soil-derived Streptomyces sp. Spiro-Oxanthromicin A inhibits mislocalisation of the oncogenic mutant K-Ras from the plasma membrane of intact Madin-Darby canine kidney (MDCK) cells. It inhibits Bacillus cereus but has no activity against HSV-1, Mycobacterium tuberculosis H37Ra and phytopathogenic fungi. Synonyms: Oxanthromicin A, spiro; (±)-spiro-oxanthromicin A; 2',7'-dihydro-2,5,6',10'-tetrahydroxy-4,5',6,8'-tetramethyl-7',10-dioxo-spiro[anthracene-9(10H),3'-[3H]benz[de]anthracene]-3,9'-dicarboxylic acid; 2,5,6',10'-tetrahydroxy-4,5',6,8'-tetramethyl-7',10-dioxo-2',7'-dihydro-10H-spiro[anthracene-9,3'-benzo[de]anthracene]-3,9'-dicarboxylic acid. Grades: ≥95% by HPLC. CAS No. 1616622-10-6. Molecular formula: C36H26O10. Mole weight: 618.58.
Spirotryprostatin B
It is a mammalian cell cycle inhibitor produced by the strain of Aspergillus fumigatus. 12.5 μg/mL of Spirotryprostatin B can inhibit the G2/M phase of the cell cycle in tsFT210 cells. Synonyms: (3S,3'S,5'aS)-6-Methoxy-3'-(2-methylprop-1-enyl)spiro[1H-indole-3,2'-5a,6,7,8-tetrahydro-3H-dipyrrolo[1,2-c:1',3'-f]pyrazine]-2,5',10'-trione; Spiro[5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-2(3H), 3'-[3H]indole]-2',5,10(1'H)-trione, 5a,6,7,8-tetrahydro-3-(2-methyl-1-propen-1-yl)-, (2S,3S,5aS)-. CAS No. 182234-26-0. Molecular formula: C21H21N3O3. Mole weight: 363.41.
Sporaricin A
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has the effect of anti-Gram-positive bacteria, Gram-negative bacteria and mycobacterium. The antibacterial activity of Sporaricin A is 8-60 times stronger than Sporaricin B. Synonyms: 1-Epi-2-deoxyfortimicin A; 2-Amino-5-[(aminoacetyl)methylamino]-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-4-O-methyl-D-allo-inositol; Antibiotic KA 6606-I; D-allo-Inositol, 2-amino-5-[(aminoacetyl)methylamino]-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-4-O-methyl-. CAS No. 68743-79-3. Molecular formula: C17H35N5O5. Mole weight: 389.49.
Sporaricin B
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It mainly has the effect of anti-Gram-positive bacteria. The antibacterial activity of Sporaricin A is 8-60 times stronger than Sporaricin B. Synonyms: Antibiotic KA 6606II; KA 6606II; D-allo-Inositol, 2-amino-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-4-O-methyl-5-(methylamino)-; 2-Amino-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-4-O-methyl-5-methylamino-2,3,5-trideoxy-D-allo-inositol; 2-Deoxyfortimycin B. CAS No. 68743-78-2. Molecular formula: C15H32N4O4. Mole weight: 332.44.
Sporaricin C
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has anti-bacterial and mycobacterium effects, and the antibacterial effect of Sporaricin C is twice as strong as Sporaricin D. Synonyms: Antibiotic KA 6606III; KA-6606-III; D-allo-Inositol, 2-amino-5- ( ( ( (aminocarbonyl) amino) acetyl) methylamino) -2, 3, 5-trideoxy-1-O- (2, 6-diamino-2, 3, 4, 6, 7-pentadeoxy-beta-L-lyxo-heptopyranosyl) -4-O-methyl-. CAS No. 68743-80-6. Molecular formula: C18H36N6O6. Mole weight: 432.52.
Sporaricin D
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has anti-bacterial and mycobacterium effects, and the antibacterial effect of Sporaricin C is twice as strong as Sporaricin D. Synonyms: 2-Amino-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-5-[[(formylamino)acetyl]methylamino]-4-O-methyl-2,3,5-trideoxy-D-allo-inositol; Antibiotic KA-6606IV; D-allo-Inositol, 2-amino-2,3,5-trideoxy-1-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-5-[[(formylamino)acetyl]methylamino]-4-O-methyl-; KA-6606-IV. CAS No. 68743-81-7. Molecular formula: C18H35N5O6. Mole weight: 417.50.
Sporaricin E
It is an aminoglycoside antibiotic produced by the strain of Saccharopolyspora hirsuta subsp. kobensis KC-6606. It has a broad antimicrobial activity. Synonyms: 2-deoxyfortimycin B; 4-Amino-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-1,4,5-trideoxy-L-chiro-inositol; Sporaricine E; L-chiro-Inositol, 4-amino-1,4,5-trideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-; Antibiotic KA 6606 VI; KA 6606-VI. CAS No. 71657-28-8. Molecular formula: C15H32N4O4. Mole weight: 332.44.
Sporaviridin
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. CAS No. 72497-34-8.
Sporaviridin A1
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Synonyms: SVD-A1; 16,35-Dioxabicyclo[29.3.1]pentatriaconta-11,19,21-trien-15-one, 3-[[O-3-amino-2,3,6-trideoxy-b-D-arabino-hexopyranosyl-(1(R)3)-O-[O-3-amino-2,3,6-trideoxy-b-D-arabino-hexopyranosyl-(1(R)3)-O-6-deoxy-b-D-glucopyranosyl-(1(R)4)]-O-[6-deoxy-b-D-glucopyranosyl-(1(R)2)]-6-deoxy-b-D-glucopyranosyl]oxy]-17-[14-[(3-amino-2,3,6-trideoxy-3-C-methyl-a-L-lyxo-hexopyranosyl)oxy]-2,8,12-trihydroxy-7,9,13-trimethylpentadecyl]-14-ethyl-29-(b-D-glucopyranosyloxy)-1,7,9,13,23,25,27,33,34-nonahydroxy-4,18,24,30-tetrame. CAS No. 107021-77-2. Molecular formula: C100H179N3O41. Mole weight: 2079.48.
Sporaviridin A2
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Synonyms: SVD-A2; Sporaviridin A1, 2-deethyl-2-methyl-; 16, 35-Dioxabicyclo[29. 3. 1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-78-3. Molecular formula: C99H177N3O41. Mole weight: 2065.45.
Sporaviridin B1
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Synonyms: SVD-B1; Sporaviridin A1, 4D-amino-4D-deoxy-; 16, 35-Dioxabicyclo[29. 3. 1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-79-4. Molecular formula: C100H180N4O40. Mole weight: 2078.49.
Sporaviridin B2
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Synonyms: SVD-B2; Sporaviridin A1, 4D-amino-2-deethyl-4D-deoxy-2-methyl-; 16, 35-Dioxabicyclo[29. 3. 1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-83-0. Molecular formula: C99H178N4O40. Mole weight: 2064.47.
Sporaviridin C1
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Synonyms: SVD-C1; Sporaviridin A1, 6D-hydroxy-; 16, 35-Dioxabicyclo[29. 3. 1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-82-9. Molecular formula: C100H179N3O42. Mole weight: 2095.48.
Sporaviridin C2
It is produced by the strain of Streptosporangium viridogriseum. The mixture of Sporaviridin have anti-Gram-positive bacteria, yeast and psoriasis fungal activity, and each component also has the same antibacterial activity. Synonyms: SVD-C2; Sporaviridin A1, 2-deethyl-6D-hydroxy-2-methyl-; 16, 35-Dioxabicyclo[29. 3. 1]pentatriacontane, sporaviridin A1 deriv. CAS No. 107021-81-8. Molecular formula: C99H177N3O42. Mole weight: 2081.45.
Sporidesmin A
It is produced by the strain of Pithomyces chartarum S-73a. It is cytotoxic to HeLa cells at a dose of 1 μg/mL. Synonyms: Sporidesmin; Hydroxysporidesmin B; 3,11a-Epidithio-11aH-pyrazino(1',2':1,5)pyrrolo(2,3-b)indole-1,4-dione, 9-chloro-2,3,5a,6,10b,11-hexahydro-10b,11-dihydroxy-7,8-dimethoxy-2,3,6-trimethyl-, (3-alpha,5a-alpha,10b-alpha,11-beta,11a-alpha)-. CAS No. 1456-55-9. Molecular formula: C18H20ClN3O6S2. Mole weight: 473.95.
Sporidesmin E
It is produced by the strain of Pithomyces chartarum S-73a. It is cytotoxic to HeLa cells at a dose of 0.1 μg/mL. Synonyms: (4R, 6aR, 11bS, 12R, 12aR)-10-chloro-11b, 12-dihydroxy-8, 9-dimethoxy-4, 7, 14-trimethyl-6a, 7, 11b, 12-tetrahydro-4, 12a-(epiminomethano)[1, 2, 3, 5]trithiazepino[5', 4':1, 5]pyrrolo[2, 3-b]indole-5, 13(4H)-dione. CAS No. 22327-77-1. Molecular formula: C18H20ClN3O6S3. Mole weight: 506.02.
Sporidesmolide complex
It is a family of five closely related cyclic depsipeptides. Sporidesmolide complex contains three dominant components, I, II and V, with less quantities of the more polar III and only traces of sporidesmolide IV. Grades: >95% by HPLC. CAS No. 11113-90-9. Molecular formula: C34H60N4O8 (for sporidesmolide II). Mole weight: 652.86 (for sporidesmolide II).
Sporidesmolide I
It is the most polar of N-methyl analogues belonging to the hexadepsipeptide sporidesmolide complex. It has no activity against a variety of bacteria and fungi. It is a depsipeptide originally isolated from S. bakeri. Synonyms: Sporidesmolide 1; cyclo[(2S)-2-hydroxy-3-methylbutanoyl-D-valyl-D-leucyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-N-methyl-L-leucyl]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-valyl]; cyclo[D-Leu-OVal-Val-N(Me)Leu-OVal-D-Val]. Grades: >95% by HPLC. CAS No. 2900-38-1. Molecular formula: C33H58N4O8. Mole weight: 638.84.
Sporidesmolide II
It is the most abundant of N-methyl analogue belonging to the hexadepsipeptide sporidesmolide complex. It is a cyclic depsipeptide originally isolated from P. chartarum. Synonyms: cyclo[D-Leu-OVal-Val-N(Me)Leu-OVal-D-aIle]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-alloisoleucyl]; (3S,6S,9S,12R,15R,18S)-15-((S)-sec-butyl)-3,12-diisobutyl-6,9,18-triisopropyl-4-methyl-1,10-dioxa-4,7,13,16-tetraazacyclooctadecane-2,5,8,11,14,17-hexaone. Grades: >95% by HPLC. CAS No. 3200-75-7. Molecular formula: C34H60N4O8. Mole weight: 652.86.
Sporidesmolide III
It is the only non-N-methylated analogue of the hexadepsipeptide sporidesmolide complex. It is the demethyl analogue of sporidesmolide I. It is a cyclodepsipeptide originally isolated from P. chartarum. Synonyms: Cyclo(3-methyl-L-2-hydroxybutanoyl-D-valyl-D-leucyl-3-methyl-L-2-hydroxybutanoyl-L-valyl-L-leucyl); cyclo[D-Leu-OVal-Val-Leu-OVal-D-Val]; cyclo[D-leucyl-N-oxa-L-valyl-L-valyl-L-leucyl-N-oxa-L-valyl-D-valyl]. Grades: >95% by HPLC. CAS No. 1803-67-4. Molecular formula: C32H56N4O8. Mole weight: 624.81.
Sporidesmolide V
It is the most non-polar of the N-methyl analogue belonging to the hexadepsipeptide sporidesmolide complex. It is a cyclodepsipeptide fungal metabolite originally isolated from Pithomyces chartarum. Synonyms: cyclo[D-Leu-OLeu-Val-N(Me)Leu-OVal-D-aIle]; cyclo[D-leucyl-N-oxa-L-leucyl-L-valyl-N-methyl-L-leucyl-N-oxa-L-valyl-D-alloisoleucyl]; cyclo(D-alloisoleucyl-D-leucyl-4-methyl-L-2-hydroxypentanoyl-L-valyl-N-methyl-L-leucyl-3-methyl-L-2-hydroxybutanoyl). Grades: >95% by HPLC. CAS No. 127072-57-5. Molecular formula: C35H62N4O8. Mole weight: 666.89.
Sporostatin
It is produced by the strain of Sporormiella sp. M5032. It inhibits cAMP-PDE with ID50 of 41 μg/mL. 1000 μg/mL of Sporostatin has no effect on Gram-positive bacteria, Gram-negative bacteria and Candida albicans. Synonyms: (+)-Sporostatin. Molecular formula: C14H14O5. Mole weight: 262.26.
Squalestatin A
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grades: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73.
Squalestatin B
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70.
Squalestatin C
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50.
SS-56C
SS-56C is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Synonyms: SS-56 C. CAS No. 39471-55-1. Molecular formula: C19H35N3O14. Mole weight: 529.5.
SS-56D
SS-56D is an aminoglycoside antibiotic produced by Streptomyces eurocidicus. It exhibits activity against gram-positive and gram-negative bacteria. Synonyms: SS-56 D. Molecular formula: C19H35N3O13. Mole weight: 513.49.
Stachartin B
Stachartin B is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone B; Spiro[benzo[2,1-b:3,4-c']difuran-2(8H),1'(2'H)-naphthalen]-8-one, 3,3',4',4'a,5',6,6',7',8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grades: 97.5%. CAS No. 1978388-55-4. Molecular formula: C23H30O5. Mole weight: 386.48.
Stachartin D
Stachartin D is produced in the cultures of the tin mine tailings-associated fungus Stachybotrys chartarum. Synonyms: Stachybotrylactone D. Grades: 97.0%. CAS No. 1978388-57-6. Molecular formula: C30H43NO6. Mole weight: 513.67.
Stachybocin A
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.3 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.3 X 10-5 and 7.9 X 10-6, respectively. Synonyms: Spirodihydrobenzofuranlactam ?; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*, 2'R*, 4'aS*, 6'R*, 8'S*)], 2'a, 4'aa, 6'a, 8'ab]]-; AM 6222A. CAS No. 158827-60-2. Molecular formula: C52H70N2O10. Mole weight: 883.12.
Stachybocin B
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.8 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.2 X 10-5 and 9.5 X 10-6, respectively. Synonyms: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'S,7'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*, 2'R*, 4'aS*, 6'R*, 8'S*)], 2'a, 4'aa, 6'a, 7'a, 8'ab]]-; AM 6222B. CAS No. 158827-61-3. Molecular formula: C52H70N2O11. Mole weight: 899.12.
Stachybocin C
It is a receptor antagonist produced by the strain of Stachybotrys sp. M6222. It inhibits the binding of I-ET-1 to rat ETA receptors with IC50 of 2.9 X 10-5 (mol/L). It also inhibits the binding of I-ET-1 to human ETA receptors and human ETB receptors with IC50 (mol/L) of 1.5 X 10-5 and 9.4 X 10-6, respectively. Synonyms: Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-[(1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl]-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, (aS,1'R,2'R,4'aS,6'S,7'R,8'aS)-; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalene]-7(3H)-hexanoic acid, a-(3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-6-oxospiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-7(3H)-yl)-3',4',4'a,5',6,6',7',8,8',8'a-decahydro-4,6',7'-trihydroxy-2',5',5',8'a-tetramethyl-6-oxo-, [1'R-[1'a[S*(1'R*, 2'R*, 4'aS*, 6'R*, 8'aS*)], 2'a, 4'aa, 6'a, 7'a, 8'ab]]-; AM 6222C. CAS No. 158827-62-4. Molecular formula: C52H70N2O11. Mole weight: 899.12.
Stachybotramide
Stachybotramide is produced by the mycelia and culture broth of Stachybotrys sp. Stachybotramide can stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). Synonyms: Spirodihydrobenzofuranlactam II; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; Stachybotrin; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-. Grades: 97.5%. CAS No. 149598-71-0. Molecular formula: C25H35NO5. Mole weight: 429.55.
Stachybotrin A
It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. CAS No. 144373-26-2. Molecular formula: C23H31NO5. Mole weight: 401.49.
Stachybotrin B
It is produced by the strain of Stachyborrys sp. It has antimicrobial and antifungal activity. Synonyms: (+)-Stachybotrin B. CAS No. 144385-02-4. Molecular formula: C23H31NO4. Mole weight: 385.50.
Stachybotrin C
It is a neuritogenic agent produced by the strain of Stachyborrys parvispora F4708. It promotes the enlargement of the neural sinus of P12 cells, and the effect of Stachybotrin C is obvious, but the effect of Parvisporin is weak. Synonyms: Pyrano[2,3-e]isoindol-7(2H)-one, 2-[(3E)-4,8-dimethyl-3,7-nonadien-1-yl]-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, (2R,3R)-rel-; Pyrano[2,3-e]isoindol-7(2H)-one, 2-(4,8-dimethyl-3,7-nonadienyl)-3,4,8,9-tetrahydro-3,5-dihydroxy-8-[2-(4-hydroxyphenyl)ethyl]-2-methyl-, [2a(E),3a]-; Antibiotic NG 245. CAS No. 150351-23-8. Molecular formula: C31H39NO5. Mole weight: 505.64.
Stachybotrolide
Stachybotrolide is produced by Stachybotrys alternans. Synonyms: Stachybotrylactone; (2R,2'R,4a'S,6'R,8a'S)-4,6'-dihydroxy-2',5',5',8a'-tetramethyl-3',4',4a',5',6',7',8',8a'-octahydro-2'H,3H-spiro[benzo[2,1-b:3,4-c']difuran-2,1'-naphthalen]-6(8H)-one; Spiro[benzo[2,1-b:3,4-c']difuran-2(3H),1'(2'H)-naphthalen]-6(8H)-one, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-; Spiro[benzo[2,1-b:3,4-c']difuran-2(3H),1'(2'H)-naphthalen]-6(8H)-one, 3',4',4'a,5',6',7',8',8'a-octahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-. Grades: 97.5%. CAS No. 149691-31-6. Molecular formula: C23H30O5. Mole weight: 386.48.
Stachybotrylactam
An unusual spirodihydrobenzofuranlactam mycotoxin isolated from Stachybotrys sp. It shows immunosuppressant and weak HIV protease activity and shows diverse activity including antiviral, endothelin and pancreatic cholesterase inhibition. Synonyms: 2-deoxy F1839A; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-3', 4', 4'a, 5', 6', 7, 7', 8, 8', 8'a-Decahydro-4, 6'-dihydroxy-2', 5', 5', 8'a-tetramethyl-spiro[2H-furo[2, 3-e]isoindole-2, 1'(2'H)-naphthalen]-6(3H)-one; Spirodihydrobenzofuranlactam I. Grades: >95% by HPLC. CAS No. 163391-76-2. Molecular formula: C23H31NO4. Mole weight: 385.50.
Stambomycin A
Stambomycin A is a macrolide antibiotic with promising antitumor activity. CAS No. 1263082-06-9. Molecular formula: C73H133NO22. Mole weight: 1376.8.
Standard Solution Aflatoxin Mixture
The acetonitrile solution of 0.5 ppm for each of four mixed Aflatoxin species: Aflatoxin B1, Aflatoxin B2, Aflatoxin G1 and Aflatoxin G2, could be commonly used as a standard solution.
Standard Solution Fumonisin B1,B2 mixture
The 50ppm for each acetonitrile-water 1:1 solution of Fumonisin B1 and Fumonisin B2, could be used as a standard solution. Molecular formula: C34H59NO15.C34H59NO14. Mole weight: 1427.66.
Standard Solution Nivalenol
Nivalenol is a trichothecene mycotoxin isolated from Fusarium. CAS No. 23282-20-4. Molecular formula: C15H20O7. Mole weight: 312.31.
Staphcoccomycin
Staphcoccomycin is a macrolide antibiotic produced by Str. sp AS-NG-16. Activity against gram-positive bacteria. Synonyms: Desmycarosyl-angolamycin. Grades: >98%. CAS No. 73047-31-1. Molecular formula: C39H65NO14. Mole weight: 771.93.
Steffimycin B
Steffimycin B is an anthracycline antibiotic produced by Str. steffisburgensis var. steffisburgensis NRRL 3193. Activity against gram-positive bacteria. Synonyms: 1,6,11(2H)-Naphthacenetrione, 4-((6-deoxy-2,4-di-O-methyl-alpha-L-mannopyranosyl)oxy)-3,4-dihydro-2,5,7-trihydroxy-3,9-dimethoxy-2-methyl-. Grades: >98%. CAS No. 54526-94-2. Molecular formula: C29H32O13. Mole weight: 588.56.
Stendomycin
Stendomycin is an ester peptide antibiotic complex produced by Str. sp. It has anti-gram-positive bacteria, mycobacteria and fungi activity. CAS No. 11006-78-3. Molecular formula: C79H137N17O19. Mole weight: 1629.03.
Sterigmatocystin
Sterigmatocystin is a mycotoxin produced by several species of aspergillus. It is structurally related to the aflatoxins. It is mutagenic, teratogenic and carcinogenic and is less widespread and potent than Aflatoxin. It inhibits acyl-CoA. It is a cholesterol acyltransferase (ACAT) with selectivity for the ACAT2 isoenzyme. Synonyms: (3aR,12cS)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; (3aR-cis)-3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo[3',2':4,5]furo[2,3-c]xanthen-7-one; NSC 201423; NSC 204985; Sterigmatocystine. Grades: >95% by HPLC. CAS No. 10048-13-2. Molecular formula: C18H12O6. Mole weight: 324.28.
A metabolite derived from streptomycin; a leading cause of ototoxicity caused by streptomycin. Synonyms: Streptamine, N,N'-bis(aminoiminomethyl)-. Grades: ≥99%. CAS No. 85-17-6. Molecular formula: C8H18N6O4. Mole weight: 262.27.
Streptimidone
Streptimidone is an antibiotic produced by Str. rimosus. It has the activity against yeast-like fungi and protozoa, and has weak antibacterial activity. Synonyms: 9-Methyl-streptimidone. CAS No. 738-72-7. Molecular formula: C16H23NO4. Mole weight: 293.36.
Streptochlorin
Streptochlorin is a metabolite originally isolated from Streptomyces sp. It exhibits antiangiogenesis, antiproliferation and antiallergic activities. It inhibits TNF-α-induced NF-κB activation. Synonyms: SF 2583A; 3-(4-chloro-5-oxazolyl)-1H-indole; Antibiotic SF 2583A. Grades: ≥98%. CAS No. 120191-51-7. Molecular formula: C11H7ClN2O. Mole weight: 218.64.
Streptocidin A
Streptocidin A is a cyclic decapeptide produced by Streptomyces sp. Tu 6071. Molecular formula: C65H90N14O13. Mole weight: 1275.49.
Streptocidin B
Streptocidin B is a cyclic decapeptide produced by Streptomyces sp. Tu 6071. Molecular formula: C67H91N15O12. Mole weight: 1298.53.
Streptonigrin
Bruneomycin is a benzoquinone antibiotic produced by Auiw-myces albus van bruneomycini and Act. echinatus. It has anti-gram-positive bacteria, negative bacteria, and mycobacterial activity. It has inhibitory effect on lymphosarcoma Lio-1, lymphocytic leukemia NK/L1 and L-5178, Ehrlich ascites carcinoma, sarcoma-180, and has inhibitory effect on sarcoma-37 invalid. Synonyms: Bruneomycin; Rufocromomycin; Nigrin; Streptonigran. Grades: >95% by HPLC. CAS No. 3930-19-6. Molecular formula: C25H22N4O8. Mole weight: 506.46.
Streptothricin A
Streptothricin A is an N-glycoside antibiotic produced by various bacteria such as Streptomyces lavendulae. It has anti-gram-positive bacteria, negative bacteria, mycobacteria and anti-fungal activity. CAS No. 3484-67-1. Molecular formula: C49H94N18O13. Mole weight: 1143.38.
Streptothricin X
Streptothricin X is an N-glycoside antibiotic produced by various bacteria such as Streptomyces lavendulae. It has anti-gram-positive bacteria, negative bacteria, mycobacteria and anti-fungal activity. CAS No. 24543-64-4. Molecular formula: C55H106N20O14. Mole weight: 1271.55.
Streptovaricin A
Streptovaricin A is a macrolide Ansa antibiotic produced by Str. spectabilis NRRL 2494. It has a broad-spectrum anti-bacterial effect, but its anti-gram-negative bacteria activity is weak. Synonyms: B-44-PC; Streptovaricin complex, fraction a. CAS No. 23344-16-3. Molecular formula: C42H53NO16. Mole weight: 827.87.
Streptovaricin B
Streptovaricin B is a macrolide Ansa antibiotic produced by Str. spectabilis NRRL 2494. It has a broad-spectrum anti-bacterial effect, but its anti-gram-negative bacteria activity is weak. Synonyms: Streptovaricin complex, fraction b; Streptovaricinoic acid, 21-acetate. CAS No. 11031-82-6. Molecular formula: C42H53NO15. Mole weight: 811.87.
Streptovaricin C
Streptovaricin C is a macrolide Ansa antibiotic produced by Str. spectabilis NRRL 2494. It has a broad-spectrum anti-bacterial effect, but its anti-gram-negative bacteria activity is weak. Synonyms: Streptovaricin. CAS No. 23344-17-4. Molecular formula: C40H51NO14. Mole weight: 769.83.
Streptovaricin J
Streptovaricin J is a macrolide Ansa antibiotic produced by Str. spectabilis NRRL 2494. It has anti-gram-positive bacteria and mycobacterial activity. CAS No. 52275-61-3. Molecular formula: C42H53NO15. Mole weight: 811.87.
Streptovitacin A
Streptovitacin A is an antibiotic produced by Str. griseus. It has antifungal and protozoan activity and can inhibit the effect of KB cells. Synonyms: Streptovitacin; Resactin A. Grades: >98%. CAS No. 523-86-4. Molecular formula: C15H23NO5. Mole weight: 297.35.
Streptovitacin B
Streptovitacin B is an antibiotic produced by Str. griseus. It has antifungal and protozoan activity and can inhibit the effect of KB cells. CAS No. 634-50-4. Molecular formula: C15H23NO5. Mole weight: 297.35.
Streptovitacin C2
Streptovitacin C2 is an antibiotic produced by Str. griseus. It has antifungal and protozoan activity and can inhibit the effect of KB cells. CAS No. 521-26-6. Molecular formula: C15H23NO5. Mole weight: 297.35.
Stresgenin B
Stresgenin B is a heat-induced heat shock protein (HSP) gene expression inhibitor produced by Streptomyces sp. AS-9. It can inhibit the expression of heat-induced luciferase reporter gene, and also inhibit the synthesis of heat-induced hsp72/73, hsp90 and hsp110. It has moderate cytotoxicity to tumor cell lines such as K562, PC6, HT29, and has antimicrobial activity against Micrococcus luteus, Staphylococcus aureus and Bacillus subtilis. Molecular formula: C11H13NO5. Mole weight: 239.22.