BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| alpha-Tocopherol quinol | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. Synonyms: 2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethylbenzoquinol; 2-(3-hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-. CAS No. 14745-36-9. Molecular formula: C29H52O3. Mole weight: 448.72. |  |
| alpha-Tocopherol spiro-dimer | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. CAS No. 1604-73-5. Molecular formula: C58H96O4. Mole weight: 857.38. | |
| Alpha-Tocopheryl Glucoside | One of the impurities of Vitamin E, which has been found to exhibit antioxidant activity. Synonyms: Tocopheryl Glucoside; alpha-Tocopherol glucoside; (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl beta-D-glucopyranoside. CAS No. 104832-72-6. Molecular formula: C35H60O7. Mole weight: 592.84. | |
| Alprenolol hydrochloride | Alprenolol hydrochloride is the hydrochloride salt of alprenolol, which is a non-selective 5-HT1A receptor antagonist and beta blocker. It is used in the treatment of angina pectoris. It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically. Uses: Adrenergic beta-antagonists. Synonyms: 1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yl)phenoxy]-2-propanol Hydrochloride; 1-(o-Allylphenoxy)-3-(isopropylamino)-2-Propanol Hydrochloride; 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol Hydrochloride; (±)-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol Hydrochloride; (±)-Alprenolol Hydrochloride; 1-(2-Allylphenoxy)-2-hydroxy-3-isopropylaminopropane Hydrochloride; Alfeprol; DL-1-(o-Allylphenoxy)-3-isopropylamino-2-propanol Hydrochloride; Dimacor; Gubernal; dl-Alprenolol Chloride. Grade: ≥99% by HPLC. CAS No. 13707-88-5. Molecular formula: C15H24NO2Cl. Mole weight: 285.81. | |
| Alprostadil alfadex | Alprostadil alfadex has a protective effect on radiation-induced proliferative inhibition and apoptosis in keratinocytes and healing of radiation-induced skin injury. Synonyms: Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-, compd. with α-cyclodextrin (1:1); 2,4,7,9,12,14,17,19,22,24,27,29-Dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane, α-cyclodextrin deriv.; α-Cyclodextrin, compd. with (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid (1:1); G 511; PGE1 α-CD; PGE1-α-cyclodextrin inclusion compd.; Prostaglandin E1-α-cyclodextrin compd.; Prostaglandin E1-α-cyclodextrin inclusion compd.; Tandetoron. Grade: ≥95%. CAS No. 55648-20-9. Molecular formula: C36H60O30.C20H34O5. Mole weight: 1327.32. | |
| Alrefimotide | Alrefimotide is an immunological agent for active immunization. Synonyms: telomerase reverse transcriptase (human TERT, hTERT, EC:2.7.7.49) (660-689)-peptide; L-alanyl-L-leucyl-L-phenylalanyl-L-seryl-L-valyl-L-leucyl-L-asparaginyl-L-tyrosyl-L-α-glutamyl-L-arginyl-L-alanyl-L-arginyl-L-arginyl-L-prolylglycyl-L-leucyl-L-leucylglycyl-L-alanyl-L-seryl-L-valyl-L-leucylglycyl-L-leucyl-L-α-aspartyl-L-α-aspartyl-L-isoleucyl-L-histidyl-L-arginyl-L-alanine; Telomerase reverse transcriptase 660-689 peptide antigen. CAS No. 1331848-79-3. Molecular formula: C146H239N45O41. Mole weight: 3280.78. | |
| Alrestatin | Alrestatin is an inhibitor of aldose reductase (IC50 = 148 μM). Uses: Specific inhibitor of aldose reductase. Synonyms: Alrestatine; 2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetic acid. Grade: ≥98%. CAS No. 51411-04-2. Molecular formula: C14H9NO4. Mole weight: 255.23. | |
| Alrestatin (sodium) | Alrestatin sodium is a specific inhibitor of aldose reductase (IC50 = 148 μM). Uses: A specific inhibitor of aldose reductase. Synonyms: Sodium; 2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetate. Grade: ≥98%. CAS No. 51876-97-2. Molecular formula: C14H8NNaO4. Mole weight: 277.21. | |
| a-L-Rhamnopyranosyl bromide triacetate | a-L-Rhamnopyranosyl bromide triacetate is a comprehensive compound with extraordinary antiviral potency, used for research of a wide range of viral infections, including the formidable influenza and herpes. Synonyms: (2S,3R,4R,5S,6S)-2-Bromo-6-methyltetrahydro-2H-pyran-3,4,5-triyl triacetate; 2,3,4-tri-O-acetyl-alpha-L-rhamnopyranosyl bromide. Grade: 97%. CAS No. 5158-64-5. Molecular formula: C12H17BrO7. Mole weight: 353.16. | |
| a-L-Rhamnopyranosyl bromide tribenzoate | a-L-Rhamnopyranosyl bromide tribenzoate is an intriguing chemical compound famed for its antimicrobial capabilities, garnering considerable research in the fight against diverse infectious diseases arising from both bacterial and fungal sources. Synonyms: 2,3,4-Tri-O-benzoyl-a-L-rhamnopyranosyl bromide. CAS No. 53297-33-9. Molecular formula: C27H23BrO7. Mole weight: 539.4. | |
| Alrizomadlin | Alrizomadlin is a highly potent and chemically stable E3 ubiquitin-protein ligase Mdm2 (Hdm2) inhibitor. It is used in the treatment and prevention of osteoarthritis. Synonyms: APG-115; AA-115; 4-((3'R,4'S,5'R)-6''-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid; APG115; APG 115; NSC831270. Grade: >98%. CAS No. 1818393-16-6. Molecular formula: C34H38Cl2FN3O4. Mole weight: 642.59. | |
| ALS-8176 (active form) | ALS-8176 (active form), a 4'-substituted cytidine analogue, is a potent, selective RSV polymerase inhibitor. It has an EC50 of 0.15 μM in the RSV replicon assay and an IC50= 0.02 μM due to its corresponding 5'-triphosphate in the RSV polymerase assay. Synonyms: 4-amino-1-[(2R,3R,4R,5R)-5-(chloromethyl)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-oneALS-8176 (active form); ALS-8112; ALS8112; ALS 8112.UNII-7795987MKM7795987MKMCHEMBL3417243SCHEMBL15070479CS-5472; HY-12983; CS 5472; HY 12983; CS5472; HY129834'-Chloromethyl-2'-deoxy-2'-fluorocytidineCytidine. Grade: 99.67%. CAS No. 1445379-92-9. Molecular formula: C10H13ClFN3O4. Mole weight: 293.68. | |
| Alsevalimab | Alsevalimab is a human monoclonal antibody that targets B7-H4 with potential antineoplastic and immune checkpoint inhibitory activities. CAS No. 2254029-91-7. | |
| Alsterpaullone | Alsterpaullone is a potent glycogen synthase kinase-3 inhibitor and a potential therapeutic agent for the treatment of Parkinson disease. Alsterpaullone is also known as 9-Nitropaullone and NSC 705701, which is a derivative of kenpaullone and an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3β (GSK3β). Alsterpaullone induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential. Alsterpaullone is a derivative of kenpaullone with slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and GSK3α/β with IC50 values of 35, 15, 200, 40, and 4 nM, respectively. Synonyms: 9-Nitropaullone; NSC 705701; 7,12-Dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one. Grade: ≥98%. CAS No. 237430-03-4. Molecular formula: C16H11N3O3. Mole weight: 293.3. | |
| Altanserin hydrochloride | Altanserin hydrochloride is the hydrochloride salt of altanserin, which is a selective and potent 5-HT2A receptor antagonist with Ki value of 0.13 nM. It is centrally active following systemic administration in vivo. It is also a useful intermediate for organic synthesis. Synonyms: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride. Grade: ≥98% by HPLC. CAS No. 1135280-78-2. Molecular formula: C22H23FN3O2SCl. Mole weight: 447.95. | |
| Alteminostat | Alteminostat is a histone deacetylase inhibitor and antineoplastic drug candidate. Alteminostat inhibits the class I-II HDAC family via histone H3 and tubulin acetylation. Uses: Histone deacetylase inhibitors. Synonyms: 1-Piperazinecarboxamide, N-(7-(hydroxyamino)-7-oxoheptyl)-4-methyl-N-(4-(1-methyl-1H-indazol-6-yl)phenyl)-; CKD-581. CAS No. 1246374-97-9. Molecular formula: C27H36N6O3. Mole weight: 492.61. | |
| Altenusin | Altenusin is a a biphenyl derivative with an IC50 value of 4.3±0.3 μM in the TR assay, which is isolated from the endophytic fungus Alternaria. It inhibits Src kinase with an IC50 value of 20 nM. Altenusin inhibits fibrillization of recombinant tau fragments in vitro and phosphorylation of tau in SH-SY5Y cells expressing human P301L mutant tau when used at a concentration of 10 μM. Altenusin is known to have antioxidant properties and to inhibit several enzymes, including myosin light chain kinase, sphingomyelinase, acetylcholinesterase, cFMS kinase, pp60c-SRc kinase and HIV-1 integrase. Synonyms: Alutenusin; MS 341; MS-341; MS341. Grade: ≥98%. CAS No. 31186-12-6. Molecular formula: C15H14O6. Mole weight: 290.27. | |
| Alternapyrone B | Alternapyrone B is an extraordinary and innovative biomedical compound, used for studying fungal ailments, notably candidiasand aspergillosis. CAS No. 2254311-61-8. Molecular formula: C28H42O5. Mole weight: 458.63. | |
| Altiratinib | Altiratinib, also known as DCC-270, DP-5164, is an oral, selective and highly potent inhibitor of MET, TIE2, VEGFR2 and TRK kinases with potential anticancer activity. DCC-2701 effectively reduces tumor burden in vivo and blocks c-MET pTyr(1349)-mediated signaling, cell growth and migration as compared with a HGF antagonist in vitro. Importantly, DCC-2701's anti-proliferative activity was dependent on c-MET activation induced by stromal human fibroblasts and to a lesser extent exogenous HGF. DCC-2701 may be superior to HGF antagonists that are in clinical trials and that pTyr(1349) levels might be a good indicator of c-MET activation and likely response to targeted therapy as a result of signals from the microenvironment. Synonyms: DCC2701; DCC 2701; DCC-2701; DP 5164; DP5164; DP-5164; Altiratinib. Grade: >98%. CAS No. 1345847-93-9. Molecular formula: C26H21F3N4O4. Mole weight: 510.46. | |
| Altizide EP Impurity B | An impurity of a thiazide diuretic Altizide. Synonyms: 3-((2,2-Dimethoxyethyl)thio)propene; 3-[(2,2-dimethoxyethyl)thio]propene. Grade: 95%. CAS No. 84522-35-0. Molecular formula: C7H14O2S. Mole weight: 162.25. | |
| Altretamine | Altretamine is an anti-neoplastic agent. Uses: An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. antineoplastic. Synonyms: 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine. Grade: > 98 %. CAS No. 645-05-6. Molecular formula: C9H18N6. Mole weight: 210.28. | |
| Altretamine hydrochloride | Altretamine hydrochloride, also called as hexamethylmelamine hydrochloride, is an alkylating agent with apparently less toxicity compared to other cytotoxic drugs used for palliation of patients with recurrent epithelial ovarian cancer. Synonyms: 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine; hydrochloride Altretamine hydrochloride Altretamine (hydrochloride) 2975-00-0 Hexamethylmelamine HCl UNII-30FQ7QG6VM 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-, monohydroch. CAS No. 2975-00-0. Molecular formula: C9H19ClN6. Mole weight: 246.74. | |
| Aluminum phthalocyanine chloride | Aluminum phthalocyanine chloride is an blue-green-coloured aromatic macrocyclic compound. It is widely used in dyeing. Phthalocyanine Chloroaluminum is a photosensitizer and it is useful in Photodynamic therapy (PDT). Synonyms: Aluminum, chloro[29H,31H-phthalocyaninato(2-)-κN29,κN30,κN31,κN32]-, (SP-5-12)-; (SP-5-12)-Chloro[29H,31H-phthalocyaninato(2-)-κN29,κN30,κN31,κN32]aluminum; 29H,31H-Phthalocyanine, aluminum complex; Aluminum, chloro[29H,31H-phthalocyaninato(2-)-N29,N30,N31,N32]-, (SP-5-12)-; Aluminum, chloro[phthalocyaninato(2-)]-; C.I. 741300; C.I. Pigment Blue 79; Chloro(phthalocyaninato)aluminum; Chloro[phthalocyaninato(2-)]aluminum; Chlorophthalocyaninealuminum; Monochloroaluminum phthalocyanine; Pigment Blue 79; SF Cyan A 209. Grade: 95%. CAS No. 14154-42-8. Molecular formula: C32H16AlClN8. Mole weight: 574.96. | |
| Aluminum phthalocyanine disulfonate | Aluminum phthalocyanine disulfonate sodium, also known as AlPcS2 disodium or AlS2Pc or AlPcS(2a), is a potent photosensitizer, and is potentially useful in cancer sonodynamic therapy and cancer photodynamic therapy. Aluminum phthalocyanine disulfonate is a mixture of regional isomers, in which sulfonate group can be in 3- or 4- position in phenyl ring. Aluminum phthalocyanine disulfonate is also a Coloring Agent; Dermatologic Agent; Fluorescent Dye; Indicators and Reagent; Luminescent Agent; Photosensitizing Agent; Radiation-Sensitizing Agent. Synonyms: Aluminate(2-), chloro[29H,31H-phthalocyanine-C,C-disulfonato(4-)-κN29,κN30,κN31,κN32]-, sodium(1:2); Aluminum phthalocyanine disulfonate disodium; AlPcS(2a), AlPcS2; AlS2Pc; ClAlPcS2 Clalpcs; Disulfonated aluminum phthalocyanine; Al(III) Phthalocyanine chloride disulfonate disodium. Grade: 98%. CAS No. 68637-19-4. Molecular formula: C32H16AlClN8O6S2. Mole weight: 779.05. | |
| Aluminum phthalocyanine tetrasulfonate tetrasodium | Aluminum phthalocyanine disulfonate is a mixture of regional isomers, in which sulfonate group can be in 3- or 4- position of phenyl ring. It is a potent photosensitizer so it is potentially useful in cancer sonodynamic therapy and cancer photodynamic therapy. This disulfonate is also a Coloring agent, Dermatologic agent and Fluorescent dye. Uses: Cancer sonodynamic therapy and cancer photodynamic therapy. Synonyms: Aluminate(4-)?, chloro[29H,?31H-phthalocyanine-2,?9,?17,?24-tetrasulfonato(6-)?-N29,?N30,?N31,?N32]?-, tetrasodium, (SP-5-13)?-,AlPcS4 or AlS4Pc, or AlPcS4(a); Chloroaluminum tetrasulfophthalocyanine; Aluminum phthalocyanine tetrasulfonate tetrasodium; Al(III) Phthalocyanine Chloride Tetrasulfonic tetrasodium. Grade: 95%. CAS No. 118887-28-8. Molecular formula: C32H12AlClN8Na4O12S4. Mole weight: 983.12. | |
| Aluminum starch octenylsuccinate | Aluminum starch octenylsuccinate is a widely employed excipient in the biomedical sector assuming a paramount role as a pivotal texture enhancer and binder within pharmaceutical formulations. Synonyms: Starch, hydrogen 2-(octen-1-yl)butanedioate, aluminum salt; Starch, hydrogen octenylbutanedioate, aluminum salt; Dry Flo Pure; Dry-Flo C; Dry-Flo PC; Dry-Flo PC 28-1800; Dry-Flo Plus; Mackaderm Asto-Dry; Octie; Octier; Okuteie; Starch octenylsuccinate aluminum salt. CAS No. 9087-61-0. | |
| Alvameline | Alvameline, also known as Lu25-109, is a partial M1agonist and M2/M3 antagonist that was progressed into clinical studies for the treatment of Alzheimer's disease and Urinary incontinence but was subsequently discontinued. Synonyms: 5-(2-ethyltetrazol-5-yl)-1-methyl-3,6-dihydro-2H-pyridine; 5-(2-ethyl-2H-tetrazol-5-yl)-1,2,3,6-tetrahydro-1-methylpyridine tartrate; LU 25-109; LU 25-109-T; LU-25-109-T. CAS No. 120241-31-8. Molecular formula: C9H15N5. Mole weight: 193.25. | |
| Alvelestat | Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE). Synonyms: AZD9668; AZD-9668; AZD 9668; MPH966; MPH 966; MPH-966; Alvelestat. Grade: 0.98. CAS No. 848141-11-7. Molecular formula: C25H22F3N5O4S. Mole weight: 545.537. | |
| Alverine | Alverine, a phenpropamine derivative, has been found to be a smooth muscle relaxant that could be used to against the spasm of the stomach, intestines and womb. Synonyms: ALVERINE; Phenopropamine; Phenpropamine; Profenil; Dipropylin; Dipropyline; N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine. Grade: 98%. CAS No. 150-59-4. Molecular formula: C20H27N. Mole weight: 281.43. | |
| Alverine Citrate | Alverine Citrate is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM. Uses: Parasympatholytics. Synonyms: N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine; 2-hydroxypropane-1,2,3-tricarboxylic acid. Grade: > 98 %. CAS No. 5560-59-8. Molecular formula: C20H27N · C6H8O7. Mole weight: 473.56. | |
| Alverine Citrate Impurity A | An impurity of Alverine Citrate. Synonyms: (3-Chloro-1-propyl)benzene, 3-Phenylpropyl chloride, Hydrocinnamyl chloride. Grade: > 95%. CAS No. 104-52-9. Molecular formula: C9H11Cl. Mole weight: 154.64. | |
| Alverine Citrate Impurity B | Alverine Citrate Impurity B is an impurity of Alverine Citrate, which is a highly potent competitive CXCR4 antagonist. It is a flavoring ingredient found in storax and fern balms, burdock fruits, guava fruit and peel, blackberries, rum, white wine, shiitake mushrooms, matsutake, and peat malt. Synonyms: Benzenepropanol; 1-Propanol, 3-phenyl-; (3-Hydroxypropyl)benzene; 1-Hydroxy-3-phenylpropane; 3-Benzenepropanol; 3-Hydroxy-1-phenylpropane; 3-Phenyl-1-propanol; 3-Phenyl-n-propanol; 3-Phenylpropanol; 3-Phenylpropyl alcohol; Dihydrocinnamic alcohol; Dihydrocinnamyl alcohol; Hydrocinnamic alcohol; Hydrocinnamyl alcohol; NSC 16942; γ-Phenylpropanol; γ-Phenylpropyl alcohol; Alverine EP Impurity B. Grade: ≥95%. CAS No. 122-97-4. Molecular formula: C9H12O. Mole weight: 136.19. | |
| Alverine Citrate Impurity C | An impurity of Alverine Citrate. Synonyms: N-Ethyl-3-phenylpropan-1-amine Hydrochloride. Grade: > 95%. CAS No. 13125-63-8. Molecular formula: C11H17N HCl. Mole weight: 163.26 36.46. | |
| Alverine Citrate Impurity E | An impurity of Alverine Citrate. Synonyms: Tris(3-phenylpropyl)amine HCl. Grade: > 95%. CAS No. 878784-75-9. Molecular formula: C27H33N HCl. Mole weight: 371.57 36.46. | |
| Alvimopan | Alvimopan is a novel, oral, peripherally acting antagonist of the mu opioid receptor, which can help gastrointestinal recovery after surgery. Phase III IC50: Mu-type opioid receptor= 1.7 nM. Uses: A peripheral μ-opioid receptor antagonist. gastroprokinetic. Synonyms: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyphenyl) pipe. Grade: ≥98%. CAS No. 156053-89-3. Molecular formula: C25H32N2O4. Mole weight: 424.53. | |
| Alvimopan Acyl Glucuronide (mixture of isomers) | A metabolite of Alvimopan. Synonyms: Alvimopan Acyl-β-D-glucuronide. Grade: > 95%. CAS No. 1260616-95-2. Molecular formula: C31H40N2O10. Mole weight: 600.67. | |
| Alvimopan-d5 Metabolite | Labelled Alvimopan Metabolite. Alvimopan is a μ-opioid receptor antagonist with limited activity of μ-opioid receptor in the central nervous system. It is indicated for postoperative ileus. Synonyms: ADL 08-0011-d5. Grade: > 95%. Molecular formula: C23H24NO3D5. Mole weight: 372.52. | |
| Alvimopan dihydrate | Alvimopan dihydrate is a novel, orally available peripherally restricted opioid antagonist with low systemic absorption. It accelerates the gastrointestinal recovery period with most common side effects in chronic pain patients with OBD were abdominal pai. Synonyms: 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; dihydrate ADL 8-2698 ADL8-2698 alvimopan alvimopan anhydrous anhydrous alvimopan Entereg LY 246736 LY-246736 LY246736 trans-3,4-dimethyl-4-(3-hydroxyph. CAS No. 170098-38-1. Molecular formula: C25H32N2O4.2H2O. Mole weight: 460.57. | |
| Alvimopan Metabolite | A metabolite of Alvimopan. Synonyms: ADL 08-0011. Grade: > 95%. CAS No. 156130-41-5. Molecular formula: C23H29NO3. Mole weight: 367.49. | |
| Alvimopan monohydrate | The monohydrate salt form of Alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (PAM-OR) antagonist with IC50: 1.7 nM. Uses: The monohydrate salt form of alvimopan could be commonly used in postoperative recovery of gastrointestinal for acting as a mu-opioid receptor (pam-or) antagonist. Synonyms: UNII-28LAR2REDG; 28LAR2REDG; DTXSID30160641; 3078AH; 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; hydrate. Grade: 98%. CAS No. 1383577-62-5. Molecular formula: C25H34N2O5. Mole weight: 442.55. | |
| Alvocidib | Alvocidib is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. Uses: For research used only. Synonyms: Flavopiridol; HMR 1275. HMR1275. HMR-1275. Grade: 0.98. CAS No. 146426-40-6. Molecular formula: C21H20ClNO5. Mole weight: 401.84. | |
| ALW-II-41-27 | ALW-II-41-27 is an effective inhibitor of EPH family kinases that has been found to be related to lung cancers. IC50: 11 nM to EPHA2. Uses: Alw-ii-41-27 is an effective inhibitor of eph family kinases that is found to be related to lung cancers. Synonyms: ALW-II-41-27; ALW II-41-27; ALWII-41-27; ALW-II-4127; ALW II-4127; ALWII-4127; MLS002232274; CHEMBL556140; DTXSID80655254; BDBM163701. Grade: 98%. CAS No. 1186206-79-0. Molecular formula: C32H32F3N5O2S. Mole weight: 607.69. | |
| ALX-1393 | ALX-1393 is a selective glycine transporter GlyT2 inhibitor that has an antinociceptive effect on thermal, mechanical and chemical stimulation in rat models of acute pain. Synonyms: (2S)-2-amino-3-((2-(benzyloxy)phenyl)(3-fluorophenyl)methoxy)propanoic acid; O-[2-benzyloxyphenyl-3-flurophenyl]methyl-L-serine; L-Serine, O-[(3-fluorophenyl)[2-(phenylmethoxy)phenyl]methyl]-. Grade: ≥95%. CAS No. 949164-09-4. Molecular formula: C23H22FNO4. Mole weight: 395.42. | |
| ALX 40-4C acetate | ALX 40-4C acetate is a small peptide inhibitor of the chemokine receptor CXCR4. It inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1. Molecular formula: C58H117N37O12. Mole weight: 1524.79. | |
| ALX 5407 hydrochloride | The hydrochloride salt form of ALX 5407, which has been found to be an inhibitor of the glycine transporter GlyT1 and could probably be useful in some neuropsychiatric disorders. Synonyms: ALX 5407 hydrochloride; ALX-5407 hydrochloride; ALX5407 hydrochloride; N-[(3R)-3-([1,1'-Biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl]-N-methylglycine hydrochloride. Grade: ≥98% by HPLC. CAS No. 200006-08-2. Molecular formula: C24H24FNO3.HCl. Mole weight: 429.92. | |
| Alytesin | Alytesin is an amphibian bombesin-like peptide originally isolated from the skin of the European amphibian, alytes obstetricans. It has biological activity very similar to bombesin. It could cause rat uterine contraction, intestinal contraction, gastric acid secretion and hypertension in vivo in the dog. It also adjusts thermoregulation following central administration in vivo. Synonyms: Alytesin; 31078-12-3; CID 16131139; XGRLGTQWAVGHLM; Alytesin (trifluoroacetate salt); BDBM85497; DTXSID40185027; Pgly-arg-leu-gly-thr-gln-trp-ala-val-gly-his-leu-met-NH2; AKOS024456835; AKOS040764257; CAS_31078-12-3; HY-103276; CS-0026803; J-018236. CAS No. 31078-12-3. Molecular formula: C68H106N22O17S. Mole weight: 1535.78. | |
| ALZ-801 | ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer's disease (AD). Compared to tramiprosate, ALZ-801 improves some critical properties including tolerability, pharmacokinetic and pharmacodynamic profile, as well as metabolic stability. It inhibits the toxic amyloid oligomers formation associated with AD, which is a discovery of new mechanism of AD prevention. Uses: Prevention of alzheimer's disease (ad). Synonyms: ALZ-801; ALZ 801; ALZ801. | |
| AM-0466 | AM-0466 is a potent and selective Nav1.7 inhibitor (IC50 = 0.020 nM). It exhibited an effective activity in a NaV1.7-dependent model of histamine-induced pruritus (itch) and also in a capsaicin-induced nociception model of pain. Synonyms: AM 0466; AM0466. CAS No. 1642113-59-4. Molecular formula: C27H19F3N4O4S. Mole weight: 552.52. | |
| AM-0687 | This active molecular is a selective PI3Kδ inhibitor. PI3Kδ is hyperactivated in B-cell malignancies and plays a vital role in the B-cell receptor pathway. AM-0687 has Cellular potency: pAKT IC50 = 0.7 nM; HWB, u (pAKT) IC 50 = 4.6 nM. AM-0687 shows excellent potency and selectivity profile in biochemical and cellular assays. Uses: Cancer drug candidate. Synonyms: AM-0687; AM 0687; AM0687. 2 - ((1S) - 1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro - N - methyl-3-(2-pyridinyl)-4-quinolinecarboxamide. Grade: 98%. CAS No. 1259522-94-5. Molecular formula: C23H19FN8O. Mole weight: 442.46. | |
| AM 0902 | AM 0902 is an effective and selective TRPA1 antagonist and has been found to exhibit activities in biological pathways associated with pain. Synonyms: AM-0902; AM 0902; AM0902. 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one. Grade: ≥98% by HPLC. CAS No. 1883711-97-4. Molecular formula: C17H15ClN6O2. Mole weight: 370.79. | |
| AM095 | AM095, an effective LPA1 receptor antagonist, has been found to decrease dermal fibrosis caused by attenuates bleomycin. IC50: 0.98 uM and 0.73 uM for human and mouse LPA1 respectively. Synonyms: AM095 (free acid); AM-095; AM 095. Grade: 98%. CAS No. 1228690-36-5. Molecular formula: C27H24N2O5. Mole weight: 456.49. | |
| AM095 sodium | AM095 is a selective LPA1 receptor antagonist. The IC50 for AM095 antagonism of LPA-induced calcium flux of human or mouse LPA1-transfected CHO cells is 0.025 and 0.023 μM, respectively. Synonyms: AM-095 sodium; AM 095 sodium. Grade: >98%. CAS No. 1345614-59-6. Molecular formula: C27H23N2NaO5. Mole weight: 478.48. | |
| AM103 | AM 103 is a potent and selective inhibitor of FLAP, with an IC50 of 4.2 nM. Synonyms: 1H-Indole-2-propanoic acid, 3-[(1,1-dimethylethyl)thio]-1-[[4-(6-methoxy-3-pyridinyl)phenyl]methyl]-α,α-dimethyl-5-(2-pyridinylmethoxy)-, sodium salt (1:1); Sodium 3-{1-[4-(6-methoxy-3-pyridinyl)benzyl]-3-[(2-methyl-2-propanyl)sulfanyl]-5-(2-pyridinylmethoxy)-1H-indol-2-yl}-2,2-dimethylpropanoate. Grade: 95%. CAS No. 1147872-22-7. Molecular formula: C36H38N3NaO4S. Mole weight: 631.76. | |
| AM-114 | AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome. In addition, AM-114 shows anticancer activity, It can inhibit cell growth in human colon cancer HCT116 p53+/+ cells. Uses: Anticancer. Synonyms: AM-114; AM 114; AM114; Proteasome Inhibitor IX; ((1Z,1'Z)-(1-methyl-4-oxopiperidine-3,5-diylidene)bis(methanylylidene))bis(4,1-phenylene))diboronic acid. Grade: 98%. CAS No. 856849-35-9. Molecular formula: C20H21B2NO5. Mole weight: 377.01. | |
| AM 1172 | AM 1172, an AEA analogue, has been found to be an anandamide uptake inhibitor as well as a cannabinoid receptor partial agonist. Synonyms: AM 1172; AM1172; AM-1172; N-(5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraen-1-yl-4-hydroxybenzamide. Grade: ≥98% by HPLC. CAS No. 251908-92-6. Molecular formula: C27H39NO2. Mole weight: 409.60. | |
| AM12 | AM12 inhibits Lanthanide-evoked TRPC5 activity with an IC50 of 0.28 μM. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one; 3,5,7-Trihydroxy-2-(2-bromophenyl)-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 2-(2-bromophenyl)-3,5,7-trihydroxy-; AM 12; AM-12. Grade: ≥90%. CAS No. 2387510-84-9. Molecular formula: C15H9BrO5. Mole weight: 349.13. | |
| AM 12 | AM 12 is a TRPC5 inhibitor with an IC50 value of 0.28 μM, which exhibits some selectivity for TRPC5 over TRPC2, 3 and 4. Synonyms: 2-(2-Bromophenyl)-3,5,7-trihydroxy-4H-chromen-4-one. Grade: ≥97%. Molecular formula: C15H9BrO5. Mole weight: 349.14. | |
| AM1241 | AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Synonyms: AM 1241; AM-1241; (1-(Methylpiperidin-2-ylmethyl)-3-(2-iodo-5-nitrobenzoyl)indole); (R,S)-3-(2-Iodo-5-nitrobenzoyl)-1-(1-methyl-2-piperidinylmethyl)-1H-indole. Grade: >98%. CAS No. 444912-48-5. Molecular formula: C22H22IN3O3. Mole weight: 503.33. | |
| AM-156 | Prostanoid GD(2) is released from mast cells in response to allergen challenge. AM156 is a selective prostanoid DP(2) receptor antagonist and it inhibits sneezing and nasal rubs in a model of allergic rhinitis. It can also inhibits pulmonary inflammation and mucus hypersecretion induced by chronic inhalation of house dust mite. AM156 may be have beneficial effects for treatment of allergic rhinitis and asthma in the future. Uses: Allergic rhinitis and asthma. Synonyms: AM-156; AM 156; AM156; UNII-5V9HJQ1Y75; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate; 1175525-98-0 (AM-156 free acid). Grade: 98%. CAS No. 1224977-85-8. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42. | |
| AM-156 sodium | AM-156 is a bio-active chemical and detailed information has not been published yet. Synonyms: AM-156 sodium; AM 156 sodium; AM156 sodium; sodium 2-(2'-((N-ethylcyclopropanecarboxamido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetate,UNII-5V9HJQ1Y75,1175525-98-0 (AM-156 free acid). Grade: 98%. CAS No. 1175525-98-0. Molecular formula: C23H23F3NNaO4. Mole weight: 457.42. | |
| AM 1714 | AM 1714, a synthetic cannabimimetic indole derivative, is a potent and selective agonist for the cannabinoid receptor. Uses: A potent and selective agonist for the cannabinoid receptor. Synonyms: AM-1714; AM 1714; AM1714; UNII-E3OY6PCU04; 6H-Dibenzo(b,d)pyran-6-one, 3-(1,1-dimethylheptyl)-1,9-dihydroxy-. Grade: ≥98%. CAS No. 335371-37-4. Molecular formula: C22H26O4. Mole weight: 354.44. | |
| AM-206 | AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; 3-Pyridineacetic acid, 5-(2-((ethyl((phenylmethoxy)carbonyl)amino)methyl)-4-(trifluoromethyl)phenyl)-, sodium salt (1:1); UNII-NCZ7ZWF0CR; 1219935-54-2 (AM-206 free acid). Grade: 98%. CAS No. 1224977-86-9. Molecular formula: C25H22F3N2NaO4. Mole weight: 494.44. | |
| AM-206 sodium | AM-206 is a bio-active chemical but no detailed data has been published yet. Synonyms: AM-206; AM 206; AM206; UNII-NCZ7ZWF0CR; (5-(2-((N-((Benzyl)oxycarbonyl)-N-ethylamino)methyl)-4-trifluoromethylphenyl)pyridin-3-yl)acetic acid. Grade: 98%. CAS No. 1219935-54-2. Molecular formula: C25H23F3N2O4. Mole weight: 472.46. | |
| AM-2099 | AM-2099 is a potent and selective inhibitor of voltage-gated sodium channel Nav1.7 (IC50 = 0.16 μM) with excellent selectivity against hNav1.5 (IC50 > 30 uM). Synonyms: 4-[2-methoxy-4-(trifluoromethyl)phenyl]-N-(1,3-thiazol-2-yl)quinazoline-7-sulfonamide; AM-2099; AM2099; AM 2099. CAS No. 1443373-17-8. Molecular formula: C19H13F3N4O3S2. Mole weight: 466.46. | |
| AM-211 | This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: AM-211; AM 211; AM211; 2-(2'-((3-benzyl-1-ethylureido)methyl)-6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)acetic acid,1263077-74-2 (AM-211 sodium). Grade: 98%. CAS No. 1175526-27-8. Molecular formula: C27H27F3N2O4. Mole weight: 500.51. | |
| AM-211 sodium | This active molecular is a potent Prostaglandin D2 receptor antagonists and has been in phase I clinical trials for both COPD (chronic obstructive pulmonary disease) and asthma, but no recent results has been published. Uses: Chronic obstructive pulmonary disease(copd) and asthma. Synonyms: UNII-8SV621U288; 1175526-27-8(Free acid); AM-211 sodium; AM 211 sodium; AM211 sodium. Grade: 98%. CAS No. 1263077-74-2. Molecular formula: C27H26F3N2O4Na. Mole weight: 522.50. | |
| AM-2159 | AM-2159 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AM-2159; AM 2159; AM2159; N6-((4-chlorophenyl)methyl)-N6-methyl- 2,4,6-Quinazolinetriamine. Grade: 98%. CAS No. 83654-06-2. Molecular formula: C16H16ClN5. Mole weight: 313.78. | |
| AM-2394 | AM-2394 is a selective Glucokinase agonist (GKA), It activates GK with an EC50 value of 60 nM. AM-2394 increases the affinity of GK for glucose by approximately 10-fold. It shows moderate clearance and good oral bioavailability in animal models, and lowers glucose excursion following an oral glucose tolerance test in an ob/ob mouse model of diabetes. Uses: Diabetes. Synonyms: AM-2394; AM 2394; AM2394; 1-(6'-(2-hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea. Grade: 98%. CAS No. 1442684-77-6. Molecular formula: C22H25N5O4. Mole weight: 423.47. | |
| AM251 | AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain. Synonyms: AM251; AM 251; AM-251. Grade: >98%. CAS No. 183232-66-8. Molecular formula: C22H21Cl2IN4O. Mole weight: 555.24. | |
| AM 281 | AM 281 has been found to be a CB1 selective receptor cannabinoid antagonist. Synonyms: AM281; AM 281; AM-281; 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 202463-68-1. Molecular formula: C21H19Cl2IN4O2. Mole weight: 557.22. | |
Our database is helping our users find suppliers everyday.
