BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| Tylvalosin | Tylvalosin, a macrolide antibiotic, is active against S. aureus, E. coli, and P. multocidas with MICs of 2, 128, and 128 μg/mL, respectively. Tylvalosin (5 and 10 μg/mL) reduces LPS-induced production of proinflammatory cytokines, prostaglandin E2 (PGE2) and nitric oxide in RAW 264.7 cells. Preparations containing tylvalosin have been used for the treatment and metaphylaxis of enzootic pneumonia caused by M. hyopneumoniae in pigs. Synonyms: 3-Acetate 4B-(3-methylbutanoate)-tylosin; 3-O-Acetyl-4''-O-isovaleryltylosin; Acetylisovaleryltylosin; 3-Acetyl-4''-isovaleryltylosin; AIV-tylosin; Tylosin acetate isovalerte; Oxacyclohexadeca-11,13-diene-7-acetaldehyde, 4-(acetyloxy)-15-[[(6-deoxy-2,3-di-O-methyl-β-D-allopyranosyl)oxy]methyl]-6-[[3,6-dideoxy-4-O-[2,6-dideoxy-3-C-methyl-4-O-(3-methyl-1-oxobutyl)-α-L-ribo-hexopyranosyl]-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-16-ethyl-5,9,13-trimethyl-2,10-dioxo-, (4R,5S,6S,7R,9R,11E,13E,15R,16R)-. Grades: ≥95%. CAS No. 63409-12-1. Molecular formula: C53H87NO19. Mole weight: 1042.25. |  |
| Type A Allatostatin III | Type A Allatostatin III is a type A allatostatin. Synonyms: H-Gly-Gly-Ser-Leu-Tyr-Ser-Phe-Gly-Leu-NH2; Glycylglycyl-L-seryl-L-leucyl-L-tyrosyl-L-seryl-L-phenylalanylglycyl-L-leucinamide; Allatostatin 8 (Diploptera punctata); Allatostatin A 3 (Diploptera punctata); Allatostatin A 3; Allatostatin III (Diploptera punctata); AST 3; AST 8; Dippu-AST 8. Grades: 95%. CAS No. 123209-96-1. Molecular formula: C42H62N10O12. Mole weight: 899.01. | |
| (Tyr0)-C-Peptide (dog) | (Tyr0)-C-Peptide (dog) is a biomedical product used to mimic the action of endogenous C-peptide hormone in dogs. It can potentially study diabetes mellitus type 1 in canines by regulating blood sugar levels and promoting insulin synthesis. Synonyms: Tyr-C-Peptide, dog; H-Tyr-Glu-Val-Glu-Asp-Leu-Gln-Val-Arg-Asp-Val-Glu-Leu-Ala-Gly-Ala-Pro-Gly-Glu-Gly-Gly-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ala-Leu-Gln-OH; L-tyrosyl-L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-arginyl-L-alpha-aspartyl-L-valyl-L-alpha-glutamyl-L-leucyl-L-alanyl-glycyl-L-alanyl-L-prolyl-glycyl-L-alpha-glutamyl-glycyl-glycyl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-alanyl-L-leucyl-L-glutamine; L-Glutamine, L-tyrosyl-L-α-glutamyl-L-valyl-L-α-glutamyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-arginyl-L-α-aspartyl-L-valyl-L-α-glutamyl-L-leucyl-L-alanylglycyl-L-alanyl-L-prolylglycyl-L-α-glutamylglycylglycyl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-α-glutamylglycyl-L-alanyl-L-leucyl-. Grades: 95%. CAS No. 101135-67-5. Molecular formula: C146H234N38O51. Mole weight: 3337.69. | |
| (Tyr0)-C-Peptide (human) | (Tyr0)-C-Peptide (human) is a C-Peptide derivative used for radioimmunoassay. Synonyms: H-Tyr-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-OH; L-tyrosyl-L-alpha-glutamyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-valyl-glycyl-L-glutaminyl-L-valyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-glycyl-L-seryl-L-leucyl-L-glutamine. Grades: ≥95% by HPLC. CAS No. 57327-90-9. Molecular formula: C138H220N36O50. Mole weight: 3183.43. | |
| (Tyr1)-pTH (1-34) (human) | Synonyms: [Tyr1] Parathyroid Hormone (1-34), human; H-Tyr-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH. Grades: ≥95% by HPLC. CAS No. 213779-10-3. Molecular formula: C189H295N55O51S2. Mole weight: 4193.87. | |
| [Tyr1]-Somatostatin | Synonyms: Tyr(1)-somatostain 14; 1-N-Tyr-somatostatin; Tyr-8-trp-somatostatin 14; Somatostatin, N-tyr(1)-. CAS No. 59481-23-1. Molecular formula: C82H108N18O20S2. Mole weight: 1729.97. | |
| (Tyr27)-α-CGRP (27-37) (canine, mouse, rat) | (Tyr27)-α-CGRP (27-37) (canine, mouse, rat) is an empirically synthesized and selectively constructed peptide, epitomizing a conspicuous fragment of Calcitonin Gene-Related Peptide (CGRP). Synonyms: [Tyr0] Calcitonin Gene Related Peptide (28-37), rat; H-Tyr-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2; L-tyrosyl-L-valyl-L-prolyl-L-threonyl-L-asparagyl-L-valyl-glycyl-L-seryl-L-alpha-glutamyl-L-alanyl-L-phenylalaninamide. Grades: 95%. CAS No. 124501-79-7. Molecular formula: C54H79N13O17. Mole weight: 1182.28. | |
| (Tyr34)-pTH (7-34) amide (bovine) | (Tyr34)-pTH (7-34) amide (bovine) is an inhibitor of the action of parathyroid hormone in vivo. Synonyms: [Tyr34] Parathyroid Hormone (7-34), amide, bovine; H-Phe-Met-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2; L-Phenylalanyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-seryl-L-seryl-L-methionyl-L-α-glutamyl-L-arginyl-L-valyl-L-α-glutamyl-3-(7H-indol-3-yl)-L-alanyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-α-aspartyl-L-valyl-L-histidyl-L-asparaginyl-L-tyrosinamide. Grades: ≥95% by HPLC. CAS No. 86292-93-5. Molecular formula: C156H244N48O40S2. Mole weight: 3496.03. | |
| (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) | (Tyr36)-pTH-Related Protein (1-36) (human, mouse, rat) has been used for radioactive iodization. Synonyms: (Tyr36)-Hypercalcemia of Malignancy Factor (1-36) (human, mouse, rat); H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Tyr-OH; (Tyr36)-pTHrP (1-36) (human, mouse, rat). Grades: ≥95%. CAS No. 213779-11-4. Molecular formula: C194H303N59O53. Mole weight: 4309.91. | |
| Tyr-CRF (human, rat) | Synonyms: CRF; H-TYR-SER-GLU-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GLU-VAL-LEU-GLU-GLU-MET-ALA-ARG-ALA-GLU-GLN-LEU-ALA-GLN-GLN-ALA-HIS-SER-ASN-ARG-LYS-LEU-MET-GLU-ILE-ILE-NH2; H-TYR-SER-GLU-GLU-PRO-PRO-ILE-SER-LEU-ASP-LEU-THR-PHE-HIS-LEU-LEU-ARG-GL. Grades: 95%. CAS No. 100513-58-4. Molecular formula: C217H353N61O65S2. Mole weight: 4920.62. | |
| Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11) | Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11), a high affinity ligand of five somatostatin receptors (SST1-SST5), has higher binding affinity than omatostatin-14 and octreotide in AtT-20 mouse anterior pituitary tumor cells expressing SST2 and SST5 receptors. Synonyms: KE 108; H-Tyr-cyclo(-D-Dab-Arg-Phe-Phe-D-Trp-Lys-Thr-Phe); L-Tyrosyl-(2R)-2,4-diaminobutanoyl-L-arginyl-L-phenylalanyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-phenylalanine (9?2)-lactam; Benzenepropanamide, α-amino-N-[(3S,6S,9S,12R,15S,18S,21S,24R)-9-(4-aminobutyl)-21-[3-[(aminoiminomethyl)amino]propyl]-6-[(1R)-1-hydroxyethyl]-12-(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,23-octaoxo-3,15,18-tris(phenylmethyl)-1,4,7,10,13,16,19,22-octaazacyclohexacos-24-yl]-4-hydroxy-, (αS)-. Grades: 95%. CAS No. 496849-46-8. Molecular formula: C67H85N15O11. Mole weight: 1276.49. | |
| Tyr-LL-37 | Tyr-LL-37 is an analog of LL-37 for radioiodination. Synonyms: [Tyr133]-Cationic Antimicrobial Protein 18 (134-170) (human); H-Tyr-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH; Tyr-hCAP-18 (134-170). Grades: ≥95%. CAS No. 2022972-74-1. Molecular formula: C214H349N61O55. Mole weight: 4656.42. | |
| Tyrocidine C | Tyrocidine C is a homodetic cyclic decapeptide, macrocyclic peptide, and antimicrobial peptide. It acts as an antimicrobial agent, metabolite, and bacterial metabolite. Synonyms: Cyclic tyrocidine C; Cyclo(L-asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-tryptophyl-D-tryptophyl); Pyrrolo[1, 2-a][1, 4, 7, 10, 13, 16, 19, 22, 25, 28]decaazacyclotriacontine, cyclic peptide deriv.; Tyrocidine A, 9-L-tryptophan-10-D-tryptophan-; Cyclo(L-tryptophyl-D-tryptophyl-L-asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl); cyclo-(D-Phe-Pro-Trp-D-Trp-Asn-Gln-Tyr-Val-Orn-Leu). CAS No. 3252-29-7. Molecular formula: C70H89N15O13. Mole weight: 1348.55. | |
| Tyrosinase (206-214) (human) | Tyrosinase (206-214) (human), a tyrosinase epitope recognized by HLA-A24-restricted tumor-infiltrating lymphocytes (TIL), represents a reagent that can be used to generate melanoma-specific T cells for adoptive immunotherapy, as well as a peptide vaccine for patients with HLA-A24+ melanoma. Synonyms: H-Ala-Phe-Leu-Pro-Trp-His-Arg-Leu-Phe-OH; L-alanyl-L-phenylalanyl-L-leucyl-L-prolyl-L-tryptophyl-L-histidyl-L-arginyl-L-leucyl-L-phenylalanine; L-Alanyl-L-phenylalanyl-L-leucyl-L-prolyl-L-tryptophyl-L-histidyl-N5-(diaminomethylene)-L-ornithyl-L-leucyl-L-phenylalanine. Grades: ≥90%. CAS No. 166188-11-0. Molecular formula: C61H83N15O10. Mole weight: 1186.41. | |
| Tyrosyl-asparagine | Tyrosyl-asparagine is a dipeptide composed of tyrosine and asparagine. Synonyms: Tyr-Asn; L-tyrosyl-L-asparagine. CAS No. 151145-11-8. Molecular formula: C13H17N3O5. Mole weight: 295.29. | |
| Tyrosyl-serine | Tyrosyl-serine is a dipeptide composed of tyrosine and serine. Synonyms: L-Tyrosyl-L-serine. CAS No. 13588-99-3. Molecular formula: C12H16N2O5. Mole weight: 268.27. | |
| Tyrosyl-threonine | Tyrosyl-Threonine is a dipeptide composed of tyrosine and threonine. Synonyms: tyrosylthreonine; Tyr-Thr; YT dipeptide; Y-T Dipeptide; H-DL-Tyr-DL-xiThr-OH. CAS No. 123952-18-1. Molecular formula: C13H18N2O5. Mole weight: 282.29. | |
| Tyr-Phe | Synonyms: Tyrosyl-Phenylalanine; L-tyrosyl-L-phenylalanine; L-Phenylalanine, L-tyrosyl-; L-Tyr-L-Phe-OH; (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-3-phenylpropanoic acid. CAS No. 17355-11-2. Molecular formula: C18H20N2O4. Mole weight: 328.36. | |
| Tyr-Proinsulin C-Peptide (55-89) (human) | Synonyms: Tyr-Insulin C chain; Tyr-Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg. CAS No. 139532-11-9. Molecular formula: C162H268N50O54. Mole weight: 3780.16. | |
| Tyr-Somatostatin-14 acetate | Tyr-Somatostatin-14 acetate is a customized peptide that adds a Tyrosine amino acid to Somatostatin-14. Synonyms: H-Tyr-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH.CH3CO2H (Disulfide bridge: Cys4-Cys15); L-tyrosyl-L-alanyl-glycyl-L-cysteinyl-L-lysyl-L-asparagyl-L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-cysteine (4->15)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C87H117N19O23S2. Mole weight: 1861.12. | |
| Tyr-Uroguanylin (mouse, rat) | Synonyms: H-Tyr-Thr-Asp-Glu-Cys-Glu-Leu-Cys-Ile-Asn-Val-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bridge: Cys5-Cys13, Cys8-Cys16); L-Cysteine, L-tyrosyl-L-threonyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-isoleucyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-, cyclic(5?13),(8?16)-bis(disulfide); L-Tyrosyl-L-threonyl-L-α -aspartyl-N-{(1R, 4S, 7S, 10S, 13S, 16R, 19S, 22S, 25R, 32S)-10-(2-amino-2-oxoethyl)-13-[(2S)-2-butanyl]-38-carboxy-22-(2-carboxyethyl)-32-[(1R)-1-hydroxyethyl]-19-isobutyl-7-isopropyl-4-methyl-3, 6, 9, 12, 15, 18, 21, 24, 30, 33, 36-undecaoxo-27, 28, 40, 41-tetrathia-2, 5, 8, 11, 14, 17, 20, 23, 31, 34, 37-undecaazabicyclo[14. 13. 13]dotetracont-25-yl}-L-α -glutamine. Grades: ≥95%. CAS No. 1926163-29-2. Molecular formula: C69H105N17O27S4. Mole weight: 1732.94. | |
| U Acetic acid | A nucleobase for PNA synthesis. Synonyms: (2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetic acid; 2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid; (2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetic acid. Grades: 98%. CAS No. 4113-97-7. Molecular formula: C6H6N2O4. Mole weight: 170.12. | |
| UCN-01 | KRX-0601, also known as UCN-01, is a synthetic derivative of staurosporine with antineoplastic activity. It inhibits many phosphokinases, including the serine/threonine kinase AKT, calcium-dependent protein kinase C, and cyclin-dependent kinases. This agent arrests tumor cells in the G1/S of the cell cycle and prevents nucleotide excision repair by inhibiting the G2 checkpoint kinase chk1, resulting apoptosis. Uses: Antineoplastic agents. Synonyms: Antibiotic UCN 01; UCN01; Staurosporine; 7-hydroxystaurosporine; KW-2401; KW 2401; KW2401; (3R,9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one; (+)-UCN-01; KRX 0601; NSC 638850. Grades: >99% by HPLC. CAS No. 112953-11-4. Molecular formula: C28H26N4O4. Mole weight: 482.53. | |
| UDP-6-azido-6-deoxy-D-Gal.2Na | Cas No. 868208-96-2. | |
| UDP-Gal.2Na | Cas No. 137868-52-1. | |
| UDP-GalNAc.2Na | Cas No. 108320-87-2. | |
| UDP-Glc | Cas No. 117756-22-6. | |
| UDP-GlcA.3Na | Cas No. 63700-19-6. | |
| UDP-GlcNAc.2Na | Cas No. 91183-98-1. | |
| UDP?Xyl.2Na | Cas No. 108320-89-4. | |
| UK-80694 | UK-80694 is a melbemycin antibiotic produced by Streptomyces hygroscopicus. It possesses anthelmintic and ectoparasiticidal activity. Synonyms: UK 80694. CAS No. 127346-84-3. Molecular formula: C42H60O12. Mole weight: 756.92. | |
| UK-80695 | UK-80695 is a melbemycin antibiotic produced by Streptomyces hygroscopicus. It possesses anthelmintic and ectoparasiticidal activity. Synonyms: UK 80695; Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-13-(2-methyl-1-oxopropoxy)-25-(1-methyl-1-propenyl)-, (6R,13R,25S)-. CAS No. 127346-86-5. Molecular formula: C38H54O9. Mole weight: 654.83. | |
| Umbilicaric acid | Umbilicaric acid is an organic polyphenolic carboxylic acid. CAS No. 30666-92-3. Molecular formula: C25H22O10. Mole weight: 482.44. | |
| Urantide acetate | Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) that blocks hU-II-induced contractions in the thoracic aorta ex vivo. Urantide has no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Urantide also exhibits partial agonist activity in a calcium mobilization assay (in CHO cells expressing hUT receptors). Synonyms: L-Valine, L-α-aspartyl-3-mercapto-L-valyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-, cyclic (2?7)-disulfide, acetate salt (1:1); H-Asp-Pen(1)-Phe-D-Trp-Orn-Tyr-Cys(1)-Val-OH.CH3CO2H; L-alpha-aspartyl-L-penicillamyl-L-phenylalanyl-D-tryptophyl-L-ornithyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide acetic acid; (S)-4-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(3-aminopropyl)-16-benzyl-4-(((S)-1-carboxy-2-methylpropyl)carbamoyl)-7-(4-hydroxybenzyl)-20,20-dimethyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-3-amino-4-oxobutanoic acid compound with acetic acid (1:1). Grades: ≥95%. Molecular formula: C53H70N10O14S2. Mole weight: 1135.32. | |
| Urdamycin A | It is produced by the strain of Str. Violaceolatus, Kerriamycin B has anti-gram-positive bacterial effect and can also prolong the survival time of patients with Ai's ascites cancer. Synonyms: Kerriamycin B; (1R)-1,5-anhydro-2,6-dideoxy-3-O-{(2S,5S,6S)-5-[(2,6-dideoxy-beta-D-arabino-hexopyranosyl)oxy]-6-methyltetrahydro-2H-pyran-2-yl}-1-[(3R,4aR,12bS)-3,4a,8-trihydroxy-12b-{[(2S,5S,6S)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-3-methyl-1,7,12-trioxo-1,2,3,4,4a,7,12,12b-octahydrobenzo[a]anthracen-9-yl]-D-arabino-hexitol. Grades: >97%. CAS No. 98474-21-6. Molecular formula: C43H56O17. Mole weight: 844.91. | |
| Urechistachykinin I acetate | Urechistachykinin I (Uru-TK I) acetate, an invertebrate tachykinin-related peptide (TRP) isolated from thylakoid nematodes, has antimicrobial activity but no hemolytic effect. Synonyms: L-Leucyl-L-arginyl-L-glutaminyl-L-seryl-L-glutaminyl-L-phenylalanyl-L-valylglycyl-L-seryl-L-argininamide acetate; Uru-TK I acetate; H-Leu-Arg-Gln-Ser-Gln-Phe-Val-Gly-Ser-Arg-NH2.CH3CO2H. Grades: ≥95%. Molecular formula: C52H89N19O16. Mole weight: 1236.38. | |
| Urocanic acid | It is produced by the strain of Bac. subtilis var. theronophilus. Urocanic acid has an inhibitory effect on Eichner's ascites pain in animals. Synonyms: 4-imidazoleacrylic acid; trans-Urocanic acid; 5-Imidazoleacrylic acid; (2E)-3-(1H-IMIDAZOL-4-YL)ACRYLIC ACID; 3-(1H-Imidazol-4-yl)-2-propenoic acid; NSC 66357. Grades: 99%. CAS No. 104-98-3. Molecular formula: C6H6N2O2. Mole weight: 138.12. | |
| Urocortin II (mouse) | Urocortin II (mouse) shows considerably high affinity for two splice variants of type 2 CRF receptor (CRF-R2) compared to CRF-R1. It activates CRF-R2α and CRF-R2β with almost the same potency as urocortin (rat). Synonyms: Ucn II (mouse); H-Val-Ile-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Arg-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Tyr-Lys-Ala-Ala-Arg-Asn-Gln-Ala-Ala-Thr-Asn-Ala-Gln-Ile-Leu-Ala-His-Val-NH2. Grades: ≥95%. CAS No. 330648-32-3. Molecular formula: C187H320N56O50. Mole weight: 4152.95. | |
| Uroguanylin | Uroguanylin belongs to the guanylin family of cyclic guanosine monophosphate (cGMP) regulatory peptides. Uroguanylin activates the guanylate cyclase-C/cyclic guanosine monophosphate pathway to induce analgesic effects in colonic hypersensitive animal models, revealing a new approach for the treatment of abdominal pain. Synonyms: Uroguanylin Topoisomer A (human); UGN Topoisomer A (human); H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15); UGN (human); L-asparagyl-L-alpha-aspartyl-L-alpha-aspartyl-L-cysteinyl-L-alpha-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparagyl-L-valyl-L-alanyl-L-cysteinyl-L-threonyl-glycyl-L-cysteinyl-L-leucine (4->12),(7->15)-bis(disulfide); L-Asparaginyl-L-α -aspartyl-N-{(1R, 4S, 7S, 10S, 13S, 16R, 19S, 22S, 25R, 32S, 38R)-10-(2-amino-2-oxoethyl)-22-(2-carboxyethyl)-38-{[(1S)-1-carboxy-3-methylbutyl]carbamoyl}-32-[(1R)-1-hydroxyethyl]-19-isobutyl-7, 13-diisopropyl-4-methyl-3, 6, 9, 12, 15, 18, 21, 24, 30, 33, 36-undecaoxo-27, 28, 40, 41-tetrathia-2, 5, 8, 11, 14, 17, 20, 23, 31, 34, 37-undecaazabicyclo[14. 13. 13]dotetracont-25-yl}-L-α -asparagine. Grades: ≥90% by HPLC. CAS No. 154525-25-4. Molecular formula: C64H102N18O26S4. Mole weight: 1667.86. | |
| Uroguanylin Topoisomer B (human) | Uroguanylin is a short peptide containing two disulfide bonds that can form interconversion topological isomers with the same disulfide connectivity. In the case of uroguanylin (UGN), both are relatively stable, separable, and slow to transform into each other. Different topoisomers have different biological activities: UGN A topomer can effectively activate the guanylate cyclase C receptor, mainly found in the intestine. The B topomer is a very weak agonist of this receptor. UGN B has strong natriuretic activity in the kidney. Synonyms: UGN Topoisomer B (human); H-Asn-Asp-Asp-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH (Disulfide bridge: Cys4-Cys12, Cys7-Cys15). Grades: ≥95%. Molecular formula: C64H102N18O26S4. Mole weight: 1667.88. | |
| Urotensin II (114-124), human acetate | Urotensin II (human) is an endogenous peptide agonist for the urotensin-II receptor (EC50 = 0.1 nM). Urotensin II (human) increases calcium levels in a concentration-dependent manner in HEK293 cells expressing human UTR (EC50 = 0.6 nM), and causes arterio-selective vasoconstriction and vasodilatation in mammals in vitro and in vivo. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5?10)-disulfide acetate; Human UII acetate; Human urotensin II acetate; Urotensin II (human) acetate; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C66H89N13O20S2. Mole weight: 1448.63. | |
| Urotensin II (Gillichthys mirabilis) acetate | Urotensin II (Gillichthys mirabilis) acetate is a peptide ligand that is the strongest known vasoconstrictor. Synonyms: Urotensin II, mouse acetate; Gillichthys mirabilis urotensin II acetate; Urotensin II (Gillichthys mirabilis reduced), cyclic (6?11)-disulfide acetate; Urotensin II (goby) acetate; L-Valine, L-alanylglycyl-L-threonyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (6?11)-disulfide acetate; H-Ala-Gly-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys6-Cys11); L-alanyl-glycyl-L-threonyl-L-alanyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (6->11)-disulfide acetate. Grades: ≥95%. Molecular formula: C64H88N14O19S2. Mole weight: 1421.61. | |
| Urotensin II, mouse acetate | Urotensin II, mouse acetate, a potent vasoconstrictor, is an endogenous ligand for the orphan GPR14 or SENR. Synonyms: L-Isoleucine, 5-oxo-L-prolyl-L-histidylglycyl-L-alanyl-L-alanyl-L-prolyl-L-α-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (8?13)-disulfide, acetate; H-Pyr-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile-OH.CH3CO2H (Disulfide bridge: Cys8-Cys13); L-pyroglutamyl-L-histidyl-glycyl-L-alanyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-isoleucine (8->13)-disulfide acetate; Urotensin II (mouse) acetate. Grades: ≥95%. Molecular formula: C78H104N18O21S2. Mole weight: 1693.92. | |
| V5 Epitope Tag Peptide acetate | V5 Epitope Tag Peptide acetate is a tag peptide derived from a small epitope on the P and V proteins of the simian virus 5 paramyxovirus. Synonyms: Glycyl-L-lysyl-L-prolyl-L-isoleucyl-L-prolyl-L-asparaginyl-L-prolyl-L-leucyl-L-leucylglycyl-L-leucyl-L-α-aspartyl-L-seryl-L-threonine acetate; H-Gly-Lys-Pro-Ile-Pro-Asn-Pro-Leu-Leu-Gly-Leu-Asp-Ser-Thr-OH.CH3CO2H. Grades: ≥95%. Molecular formula: C66H112N16O22. Mole weight: 1481.65. | |
| (Val1259)-Laminin α-4 Chain (1259-1266) (human) | Synonyms: (Val1254)-Laminin α-4 Chain (1254-1261) (mouse); H-Val-Gly-Phe-Asn-Phe-Arg-Thr-Leu-OH. Grades: ≥95%. Molecular formula: C45H68N12O11. Mole weight: 953.09. | |
| (Val2)-Amyloid β-Protein (1-42) | This is a mutation very close to the APP (A673V) β-secretase cleavage site. In contrast to the protective Icelandic mutation A2T, the recessive A2V mutation may increase the risk of Alzheimer's disease. APP A673V is associated with the early onset of AD dementia in homozygous individuals and has a protective effect in the heterozygous states. Synonyms: H-Asp-Val-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grades: ≥95%. Molecular formula: C205H315N55O60S. Mole weight: 4542.16. | |
| (Val2)-Amyloid β-Protein (1-6) | Synonyms: H-Asp-Val-Glu-Phe-Arg-His-OH; L-α-Aspartyl-L-valyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidine; H-DVEFRH-OH. Grades: ≥95%. CAS No. 727727-66-4. Molecular formula: C35H51N11O11. Mole weight: 801.86. | |
| (Val34)-Amyloid β-Protein (1-40) | Cerebral amyloid angiopathy (CAA) is a common manifestation of Alzheimer's disease, characterized by amyloid-Aβ vascular deposition in >80% of cases. Mutations at sites 21-23 (such as the Dutch mutation E22Q) are primarily associated with CAA, although they present with significantly different clinical phenotypes: cerebral hemorrhage or dementia. The Piedmont L34V Aβ mutant lies outside this hot spot, showing a similar bleeding phenotype, though less aggressive than the widely studied Dutch variant. Synonyms: Amyloid β-Protein (1-40) L34V; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Val-Met-Val-Gly-Gly-Val-Val-OH. Grades: ≥95%. CAS No. 1678415-83-2. Molecular formula: C193H293N53O58S. Mole weight: 4315.84. | |
| (Val3,Pro8)-Oxytocin | (Val3,Pro8)-Oxytocin, the I3V/L8P variant of oxytocin binding to OT and AVP V1 receptors, is produced by the Saguinus genus of the Callitrichidae family of New World monkeys. When interacting with V1, (Pro8)-OT and oxytocin produce similar signal profiles and are equally effective against Gq and β-arrestin, while (Val3,Pro8)-OT is less effective against β-arrestin. Intranasal application of OT L8P and OT I3V/L8P enhanced parental behavior in rats. Synonyms: H-Cys-Tyr-Val-Gln-Asn-Cys-Pro-Pro-Gly-NH2 (Disulfide bridge: Cys1-Cys6); (Val3,Pro8)-OT. CAS No. 2134138-89-7. Molecular formula: C41H60N12O12S2. Mole weight: 977.12. | |
| (Val9)-Oxytocin | (Val9)-Oxytocin, a conopressin T analog, has increased affinity for V1a receptors and weak binding to V2 receptors. Oxytocin and (Val9)-Oxytocin exhibit the same properties, while native conopressin T (CYIQNCLRV-NH2) only binds to OT and V1a receptors. Synonyms: G9V-OT; H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Val-NH2 (Disulfide bridge: Cys1-Cys6); conopressin T L7P/R8L. CAS No. 1021701-88-1. Molecular formula: C46H72N12O12S2. Mole weight: 1049.27. | |
| Valacyclovir Impurity K | An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Molecular formula: C14H18N10O4. Mole weight: 390.36. | |
| Valacyclovir Impurity N | An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Synonyms: Guaninyl Valacyclovir; N2-(Guanine-N2-yl)methyl]-9-[(2-hydroxyethoxy)methyl]guanine-L-valinate. Molecular formula: C19H25N11O5. Mole weight: 487.48. | |
| Valacyclovir Impurity O | An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Molecular formula: C22H33N11O7. Mole weight: 563.58. | |
| Valacyclovir Impurity Q | An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Molecular formula: C19H25N11O5. Mole weight: 487.48. | |
| Valacyclovir Related Compound C | Valacyclovir Related Compound C is an amino acid ester of Acyclovir used as an antiherpetic agent. Synonyms: Acyclovir L-Leucinate; L-Leucine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl Ester Hydrochloride. CAS No. 142963-69-7. Molecular formula: C14H22N6O4 HCl. Mole weight: 374.82. | |
| Valacyclovir Related Compound E | An impurity of Valaciclovir. Valacyclovir is the prodrug of acyclovir used to treat infectious diseases. Synonyms: N-Carboxybenzyl D-Valacyclovir; N(Val)-Carboxybenzyl Valacyclovir; N-[(Phenylmethoxy)carbonyl]-D-valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]Ethyl Ester. CAS No. 124832-32-2. Molecular formula: C21H26N6O6. Mole weight: 458.48. | |
| Val-Arg | Synonyms: L-valyl-L-arginine; valylarginine; VR dipeptide; L-Val-L-Arg; Valine Arginine dipeptide. CAS No. 37682-75-0. Molecular formula: C11H23N5O3. Mole weight: 273.33. | |
| Valorphin | Valorphin is an endogenous hemoglobin β-chain (33-39) fragment. Valorphin has opioid analgesic activity, binds to rat mu-opioid receptor, with an IC50 of 14 nM. Synonyms: H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH. Grades: 95%. CAS No. 144313-54-2. Molecular formula: C44H61N9O11. Mole weight: 892.01. | |
| Valorphin TFA | Valorphin TFA is an endogenous hemoglobin β-chain (33-39) fragment. It has opioid analgesic activity, and binds to rat mu-opioid receptor, with an IC50 of 14 nM. Synonyms: H-Val-Val-Tyr-Pro-Trp-Thr-Gln-OH.TFA; L-valyl-L-valyl-L-tyrosyl-L-prolyl-L-tryptophyl-L-threonyl-L-glutamine trifluoroacetic acid. Grades: ≥95%. Molecular formula: C46H62F3N9O13. Mole weight: 1006.03. | |
| Val-Ser | Valylserine inhibits melanin synthesis in Mel-Ab cells through down-regulation of tyrosinase. Synonyms: L-valyl-L-serine; Valylserine; N-L-Valyl-L-serine; L-Val-L-Ser; VS dipeptide; (S)-2-((S)-2-Amino-3-methylbutanamido)-3-hydroxypropanoic acid. Grades: 95%. CAS No. 13588-94-8. Molecular formula: C8H16N2O4. Mole weight: 204.22. | |
| Valspodar | Valspoda, an analog of cyclosporine A, induces caspase-mediated apoptosis. It inhibits multidrug-resistant efflux pump P-glycoprotein, thereby restoring retention and activity of some drugs in some drug-resistant tumor cells. Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. Synonyms: 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]-7-L-valine-cyclosporin A; 6-[[R-(E)]-6,7-Didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid]-7-L-valinecyclosporin A; 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]cyclosporin D; Amdray; PSC 833; SDZ-PSC 833; Valpodar; Cyclo(((2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl)-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl). Grades: ≥95%. CAS No. 121584-18-7. Molecular formula: C63H111N11O12. Mole weight: 1214.62. | |
| Val-Tyr-Val | Peptidic compound in various cosmetic formulations. Synonyms: (2S)-2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoic acid; VYV; H-Val-Tyr-Val-OH. CAS No. 17355-22-5. Molecular formula: C19H29N3O5. Mole weight: 379.45. | |
| Valyl-leucyl-lysyl-4-aminomethylcoumarin | A sensitive and highly specific fluorescent substrate for plasmin. Synonyms: H-D-Val-leu-lys 4-aminomethyl coumarin; L-Lysinamide, D-valyl-L-leucyl-N-((2-oxo-2H-1-benzopyran-4-yl)methyl)-. Grades: >98%. CAS No. 148168-23-4. Molecular formula: C27H41N5O5. Mole weight: 515.64. | |
| Valyllysine | Valyl-lysine is a dipeptide composed of valine and lysine. Synonyms: Val-lys; l-valyl-l-lysine; Valyl-lysine; L-Lysine, L-valyl-; VK dipeptide; Valine Lysine dipeptide. CAS No. 22677-62-9. Molecular formula: C11H23N3O3. Mole weight: 245.32. | |
| Vancomycin EP Impurity A | Vancomycin EP Impurity A is a glycopeptide antibiotic produced by Nocardia orientalis A51568.1. Activity against gram-positive bacteria. Synonyms: N2.1-demethylvancomycin B; N-Demethyl Vancomycin B; Norvancomycin; A51568 A. CAS No. 91700-98-0. Molecular formula: C65H73Cl2N9O24. Mole weight: 1435.22. | |
| Vanilglycolic Acid | Synonyms: (4-hydroxy-3-methoxyphenyl)(oxo)acetic acid; AC1L4VQG; AC1Q5RGU; 4-Hydroxy-3-methoxy-alpha-oxobenzeneacetic acid. CAS No. 2021-40-1. Molecular formula: C9H8O5. Mole weight: 196.16. | |
| Vasonatrin Peptide (VNP) Trifluoroacetate | Vasonatrin peptide (VNP) is a chimera of atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP) with potent venodilating and natriuretic activity. Synonyms: [Cys6-Cys22] Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr. CAS No. 141676-35-9. Molecular formula: C126H199F3N36O38S3. Mole weight: 2979.33. | |
| Vernakalant | Vernakalant is an drug under regulatory for the treatment for conversion of atrial fibrillation. It blocks atrial potassium channels, thereby prolonging repolarization. It differs from typical class III agents and is more effective at high heart rates. It also slightly blocks the hERG potassium channel, leading to a prolonged QT interval. It also blocks atrial sodium channels. It was initially developed by Cardiome Pharma, and the intravenous formulation was bought for further development by Merck in April 2009. In September 2012, Merck terminated its agreements with Cardiome and has consequently returned all rights of the drug back to Cardiome. The drug (under brand name Brinavess) was approved in Europe on 1 September 2010. An oral formulation underwent Phase II clinical trials between 2005 and 2008. Uses: Vernakalant is an drug under regulatory for the treatment for conversion of atrial fibrillation. it blocks atrial potassium channels, thereby prolonging repolarization. it also slightly blocks the herg potassium channel, leading to a prolonged qt interval. it also blocks atrial sodium channels. Synonyms: Brinavess; RSD1235; (3R) -1-[ (1R, 2R) -2-[2- (3, 4-dimethoxyphenyl) ethoxy]cyclohexyl]pyrrolidin-3-ol. Grades: 95%. CAS No. 794466-70-9. Molecular formula: C20H31NO4. Mole weight: 349.47. | |
| Verticillin A | Verticillin A is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: (6S,6'S)-19,19'-Dideoxy-6,6'-dihydroxychetocin. CAS No. 32164-16-2. Molecular formula: C30H28N6O6S4. Mole weight: 696.84. | |
| Verticillin C | Verticillin C is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: Verticillin C. Grades: 95%. CAS No. 51798-48-2. Molecular formula: C30H28N6O7S5. Mole weight: 744.90. | |
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