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Tide FluorTM 5WS-Amyloid β-Protein (1-40)
Fluorescent dye-labeled Aβ40, excitation at 649 nm, emission at 664 nm. Tide FluorTM 5WS has strong fluorescence and excellent photostability. Synonyms: Tide FluorTM 5WS-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH. Grades: ≥90%. Molecular formula: C194H295N53O58S + dye. Mole weight: 5062.
Tide FluorTM 5WS-Amyloid β-Protein (1-42)
Fluorescently labeled Aβ42, excitation at 649 nm, emission at 664 nm. Tide FluorTM 5WS is a photostable fluorophore. Synonyms: Tide FluorTM 5WS-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH. Grades: ≥90%. Molecular formula: C203H311N55O60S + dye. Mole weight: 5246.
Tide FluorTM 5WS-ω-Conotoxin GVIA
Tide FluorTM 5WS-ω-Conotoxin GVIA is fluorescent dye-labeled ω-Conotoxin GVIA from the venom of the fish-hunting cone snail C. geographus, excitation at 649 nm, emission at 664 nm. Tide FluorTM 5WS has strong fluorescence and excellent photostability. The cone snail venom effectively blocks calcium channels in neurons. This presynaptic inhibition of calcium influx prevents voltage-activated acetylcholine release. Synonyms: Tide FluorTM 5WS-Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys19, Cys15-Cys26). Molecular formula: C120H182N38O43S6 + dye. Mole weight: 3769.
Tide FluorTM 7WS-Amyloid β-Protein (1-40)
Fluorescent dye-labeled Aβ40, excitation at 749 nm, emission at 775 nm. Tide FluorTM 7WS has strong fluorescence and excellent photostability. Synonyms: Tide FluorTM 7WS-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH. Grades: ≥90%. Molecular formula: C194H295N53O58S + dye. Mole weight: 5088.
Tirandamycin A
Tirandamycin A is originally isolated from Str. tirandis var. tirandis NRRL 3689, and it has anti-gram-positive bacteria effect. Synonyms: NSC 107067; 3-Pyrrolin-2-one, 4-hydroxy-3-(4-methyl-6-(1,2,7-trimethyl-5-oxo-3,9,10-trioxatricyclo(4.3.1.0(sup 2,4))dec-8-yl)-2,4-heptadienoyl)-, (E,E)-. Grades: 95% by HPLC. CAS No. 34429-70-4. Molecular formula: C22H27NO7. Mole weight: 417.45.
Tirzepatide acetate
Tirzepatide acetate is a dual GIP and GLP-1 receptor agonist used as a drug candidate for the treatment of type 2 diabetes. Synonyms: L-Tyrosyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-tyrosyl-L-seryl-L-isoleucyl-2-methylalanyl-L-leucyl-L-α-aspartyl-L-lysyl-L-isoleucyl-L-alanyl-L-glutaminyl-N6-[(22S)-22,42-dicarboxy-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazadotetracont-1-yl]-L-lysyl-L-alanyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-alanylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide acetate salt; LY 3298176 acetate salt; LY3298176 acetate salt; Tyr-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys-diacid-gamma-Glu-(AEEA)2-Lys-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 acetate salt. Molecular formula: C227H352N48O70. Mole weight: 4873.58.
Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant. Synonyms: 2-Methyl-1-(4-methylphenyl)-3-(1-piperidinyl)-1-propanone Hydrochloride; 2,4'-Dimethyl-3-piperidinopropiophenone Hydrochloride; 2,4'-Dimethyl-3-piperidino-propiophenone Hydrochloride. Grades: >98%. CAS No. 3644-61-9. Molecular formula: C16H23NO.HCl. Mole weight: 281.82.
Tomaymycin
It is originally isolated from Str. achromogenes var. tomaymyceticus A-2127. Tomaymycin is resistant to gram-positive bacteria and fungi, and has a weak effect on E. coli. Synonyms: NSC 177499; 2-Ethylidene-1,2,3,10,11,11a-hexahydro-8-hydroxy-7,11-dimethoxy-5H-pyrrolo(2,1-c)(1,4)benzodiazepin-5-one. CAS No. 35050-55-6. Molecular formula: C16H20N2O4. Mole weight: 304.34.
Torreyanic acid
Torreyanic acid is a dimer quinone obtained from the endophytic bacterium Pestalotiopsis microspora. Torreyanic acid is cytotoxic to tumor cells and is 5-10 times more effective in cell lines sensitive to protein kinase C agonists. CAS No. 176260-42-7. Molecular formula: C38H44O12. Mole weight: 692.75.
Torsemide
Torsemide is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 μM. Synonyms: 3-Pyridinesulfonamide, N-[[(1-methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-; N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide; 1-([4-[(3-Methylphenyl)amino]pyridin-3-yl]sulfonyl)-3-(propan-2-yl)urea; AC 4464; BM 02.015; BM 02015; Britomar; Demadex; Dilutol; Examide; Isemid; JDL 464; Luprac; Tide 10; Toradiur; Torasemide; Torem; Unat; UpCard. Grades: >98%. CAS No. 56211-40-6. Molecular formula: C16H20N4O3S. Mole weight: 348.42.
Tos-Gly-Pro-Lys-AMC
It is a fluorogenic substrate for trypsin, gingipain K, and cathepsin L. Synonyms: (2S)-N-(2-Oxo-4-methyl-2H-1-benzopyran-7-yl)-2-[(Tos-Gly-Pro-)amino]-6-aminohexanamide. Grades: >98%. CAS No. 128202-25-5. Molecular formula: C30H37N5O7S. Mole weight: 611.71.
Tos-Gly-Pro-Lys-pNA
Synonyms: (S) -N- ( (S) -6-amino-1- (4-nitrophenylamino) -1-oxohexan-2-yl) -1- (2- (4-methylphenylsulfonamido) acetyl) pyrrolidine-2-carboxamide. CAS No. 73392-19-5. Molecular formula: C26H34N6O7S. Mole weight: 574.65.
Tos-Gly-Pro-OH
Synonyms: (S) -1- (2- (4-Methylphenylsulfonamido) acetyl) pyrrolidine-2-carboxylic acid. CAS No. 100723-71-5. Molecular formula: C14H18N2O5S. Mole weight: 326.37.
Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78)
Toxic Shock Syndrome Toxin-1 (TSST-1) (58-78) has an active site for TSST-1 holotoxin that binds to MHC class II molecules and can xenostimulate T cells in an MHC-unrestricted manner. TSST-1 is a ''superantigen'' that binds MHC class II molecules and induces T cell stimulation. Synonyms: H-Lys-Gly-Glu-Lys-Val-Asp-Leu-Asn-Thr-Lys-Arg-Thr-Lys-Lys-Ser-Gln-His-Thr-Ser-Glu-Gly-OH; Tsst-1 (58-78); L-lysyl-glycyl-L-alpha-glutamyl-L-lysyl-L-valyl-L-alpha-aspartyl-L-leucyl-L-asparagyl-L-threonyl-L-lysyl-L-arginyl-L-threonyl-L-lysyl-L-lysyl-L-seryl-L-glutaminyl-L-histidyl-L-threonyl-L-seryl-L-alpha-glutamyl-glycine. Grades: ≥95% by HPLC. CAS No. 137593-46-5. Molecular formula: C98H171N33O35. Mole weight: 2371.61.
T-Peptide
T-peptide, a highly neurotoxic cell-permeable analog of PHF6, can be used in the study of human immunodeficiency virus (HIV) infection. T-peptide can induce Tau peptide aggregation, prevent cellular immunosuppression, improve the survival rate of sepsis mice, and inhibit the growth of residual tumor cells after surgical resection. Synonyms: PHF6-R9; L-Argininamide, N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-; Ac-D-Val-D-Gln-D-Ile-D-Val-D-Tyr-D-Lys-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2; N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-argininamide. Grades: ≥95%. CAS No. 2022956-62-1. Molecular formula: C92H171N45O18. Mole weight: 2195.66.
TRAF6 Control Peptide
TRAF6 Control Peptide is an inactive control of the TRAF6-p62 interaction modulator, and the sequence is different in three positions. Synonyms: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Glu-Ser-Ala-Ser-Gly-Ala-Ser-Ala-Asp-Ala-Ser-Val-Asn-Phe-Leu-Lys-OH; L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-seryl-glycyl-L-alanyl-L-seryl-L-alanyl-L-alpha-aspartyl-L-alanyl-L-seryl-L-valyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-lysine. Grades: ≥95%. CAS No. 852690-80-3. Molecular formula: C139H232N34O42. Mole weight: 3051.53.
TRAF6 Peptide
TRAF6 Peptide, a cell-permeable peptide, inhibits the interaction of TRAF6 (E3 ubiquitin ligase) with P62 (sequestosome 1). P62 is a polyubiquitin shuttling factor that binds to K63-polyubiquitinated proteins. The TRAF6-p62 interaction modulators can be used to treat neuropathology, such as Alzheimer's disease or Huntington's disease. Synonyms: TRAF6 (cell permeable); H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Glu-Ser-Ala-Ser-Gly-Pro-Ser-Glu-Asp-Pro-Ser-Val-Asn-Phe-Leu-Lys-OH; L-alanyl-L-alanyl-L-valyl-L-alanyl-L-leucyl-L-leucyl-L-prolyl-L-alanyl-L-valyl-L-leucyl-L-leucyl-L-alanyl-L-leucyl-L-leucyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-seryl-glycyl-L-prolyl-L-seryl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-seryl-L-valyl-L-asparagyl-L-phenylalanyl-L-leucyl-L-lysine. Grades: ≥95%. CAS No. 852805-92-6. Molecular formula: C145H238N34O44. Mole weight: 3161.64.
Trans-1-Hydroxy-2,7-diamino Mitosene is an impurity of Mitocycin. Mitomycin is a drug which is used for treatment of malignant neoplasm of lip. Synonyms: (1R-trans)-2,7-Diamino-9-[[(aminocarbonyl)oxy]methyl]-2,3-dihydro-1-hydroxy-6-methyl-1H-Pyrrolo[1,2-a]indole-5,8-dione. CAS No. 99745-88-7. Molecular formula: C14H16N4O5. Mole weight: 320.30.
trans-4-Hydroxy-lomustine
trans-4-Hydroxy-lomustine is an impurity of lomustine which is a chloroethylnitrosourea derivative with antitumor activity. Lomustine is similar to carmustine, chlorozotocin, nimustine, and ranimustine. Synonyms: 1-(2-Chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nitrosourea; N-(2-Chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitrosourea; NSC 239717; trans-4-Hydroxy CCNU. Grades: > 95%. CAS No. 56239-24-8. Molecular formula: C9H16ClN3O3. Mole weight: 249.69.
trans-4-Hydroxymellein
It is produced by the strain of Apiospora camptospora and marine-derived Microsphaeropsis sp. H5-50. It is the constituent of Moringa oleifera (horseradish tree) and Septoria nodorum. Synonyms: 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3R,4S)-; (3R,4S)-hydroxymellein; (3R,4S)-4,8-dihydroxy-3-methylisochroman-1-one; 1H-2-Benzopyran-1-one, 3,4-dihydro-4,8-dihydroxy-3-methyl-, (3R-trans)-; (-)-trans-4-hydroxymellein. CAS No. 70287-70-6. Molecular formula: C10H10O4. Mole weight: 194.18.
(trans)-4-Propyl-1-methyl-L-proline
Lincomycin EP Impurity E is an impurity of Clindamycin, which is a semi-synthetic antibiotic prepared from Lincomycin. Synonyms: Lincomycin EP Impurity E. Grades: 95%. CAS No. 13380-36-4. Molecular formula: C9H17NO2. Mole weight: 171.24.
trans-Cyclooct-2-en-L-Lysine
Cas No. 1801936-26-4. Molecular formula: C15H26N2O4. Mole weight: 298.38.
Transdermal Peptide acetate
Transdermal Peptide acetate binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Synonyms: TD 1 (peptide) acetate. Molecular formula: C42H68N14O18S2. Mole weight: 1121.2.
Loperamide oxide (LOPOX) is a prodrug of Loperamide (LOP). It is concluded that Loperamide oxide administered intraluminally is reduced to Loperamide and has the same antisecretory potency as Loperamide in jejunum and colon. Uses: Antidiarrheals. Synonyms: trans-4-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutanamide 1-Oxide; Arestal; Loperamide Oxide; R 58425. Grades: > 95%. CAS No. 106900-12-3. Molecular formula: C29H33ClN2O3. Mole weight: 493.04.
trans-Violaxanthin
Violaxanthin is a natural xanthophyll pigment with an orange color found in a variety of plants. Violaxanthin is mainly used as a food additive. Synonyms: Violaxanthin; All-trans-Violaxanthin; (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'-TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL; XAT; Zeaxanthin diepoxide. CAS No. 126-29-4. Molecular formula: C40H56O4. Mole weight: 600.89.
TRAP-14
TRAP-14 is a synthetic thrombin receptor agonist peptide and causes platelet aggregation (EC50 = 4 μM) and secretion. Synonyms: PAR-1 (1-14) (human); H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH; L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagyl-L-prolyl-L-asparagyl-L-alpha-aspartyl-L-lysyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-phenylalanine. Grades: ≥95% by HPLC. CAS No. 137339-65-2. Molecular formula: C81H118N20O23. Mole weight: 1739.92.
TRAP-5 amide
TRAP-5 amide is an agonist of thrombin receptor. Synonyms: SFLLRamide; H-SFLLR-NH2; L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-argininamide; (S)-2-((S)-2-((S)-2-amino-3-hydroxypropanamido)-3-phenylpropanamido)-N-((S)-1-((S)-1-amino-5-guanidino-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-4-methylpentanamide. Grades: 95%. CAS No. 141923-41-3. Molecular formula: C30H51N9O6. Mole weight: 633.78.
TRH-βNA is a sensitive and highly specific substrate for a rapid assay of rat brain TRH-deamidating enzyme (prolyl endopeptidase). Synonyms: L-Prolinamide,5-oxo-L-prolyl-L-histidyl-N-2-naphthalenyl-(9ci); 5-Oxo-L-prolyl-L-histidyl-N-2-naphthalenyl-L-prolinamide. CAS No. 73644-58-3. Molecular formula: C26H28N6O4. Mole weight: 488.54.
Trichodimerol
BMS-182123 is a substance produced by Penicillum chrysogenum V39673 that can inhibit the production of Tumor necrosis factor (TNF-a). The IC50 of inhibiting lipopolysaccharide (LPS) induced TNF-a in murine macrophages and human monocytes were 600 ng/mL and 4.0 μg/mL, respectively. Synonyms: BMS-182123. CAS No. 145174-90-9. Molecular formula: C28H32O8. Mole weight: 496.55.
Trichostatin A
Trichostatin A, also known as TSA, is an HDAC inhibitor. TSA inhibits the eukaryotic cell cycle during the beginning of the growth stage. TSA can be used to alter gene expression by interfering with the removal of acetyl groups from histones (histone deacetylases, HDAC) and therefore altering the ability of DNA transcription factors to access the DNA molecules inside chromatin. It is a member of a larger class of histone deacetylase inhibitors (HDIs or HDACIs) that have a broad spectrum of epigenetic activities. Uses: Reprogramming. Synonyms: TSA; Antibiotic A-300; 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide. Grades: 98%. CAS No. 58880-19-6. Molecular formula: C17H22N2O3. Mole weight: 302.37.
Trichostatin D
Trichostatin D is a metamorphosis cell phenotype recovery inducer produced by the strain of Streptomyces violaceusniger. Synonyms: 1-O-({(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxohepta-2,4-dienoyl}amino)-alpha-D-glucopyranose. CAS No. 157479-37-3. Molecular formula: C23H32N2O8. Mole weight: 464.51.
Triclosan
Triclosan is a broad-spectrum antibacterial and antifungal agent added in consumer products such as toothpaste, soaps, detergents, etc. Synonyms: Cloxifenolum; Irgasan. CAS No. 3380-34-5. Molecular formula: C12H7Cl3O2. Mole weight: 289.5.
Tricyclic amide linker resin (DL-form)
Ramage resin is highly suitable for the preparation of peptide amides by the Fmoc-strategy and is recommended for C-terminal Phe, Tyr and Ile. Synonyms: Ramage amide linker resin (DL-form) (200-400 mesh).
Triethylenetetramine dihydrochloride
Triethylenetetramine Hydrochloride is a selective CuII-chelator, undergoing trials for the treatment of heart failure in patients with diabetes. Uses: A selective cuii-chelator. Synonyms: N'-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine;dihydrochloride. Grades: ≥ 95 %. CAS No. 38260-01-4. Molecular formula: C6H20Cl2N4. Mole weight: 219.16.
Trifluperidol
Trifluperidol is an antipsychotic butyrophenone that is used for the treatment of mania and schizophrenia. Uses: Antipsychotic agents. Synonyms: Triperidol; Trisedil; Psychoperidol; Flumoperone; Psicoperidol. CAS No. 749-13-3. Molecular formula: C22H23F4NO2. Mole weight: 409.43.
Trimegestone
Trimegestone is a steroidal progestin used as hormonal contraceptive used in hormonal replacement therapy of postmenopausal symptoms. Synonyms: [17β(S)]-17-(2-Hydroxy-1-oxopropyl)-17-methyl-estra-4,9-dien-3-one; RU 27987. CAS No. 74513-62-5. Molecular formula: C22H30O3. Mole weight: 342.48.
Trimetazidine DiHCl
Trimetazidine dihydrochloride, a piperazine derivative, could reduce fatty acid β-oxidation and used as a coronary vasodilator. Uses: Trimetazidine dihydrochloride could reduce fatty acid β-oxidation and used as a coronary vasodilator. Synonyms: 1-[(2, 3, 4-trimethoxyphenyl)methyl]piperazine; dihydrochloride. Grades: 95 %. CAS No. 13171-25-0. Molecular formula: C14H22N2O3 · 2HCl. Mole weight: 339.26.
Trimipramine N-Glucuronide
metabolite of Trimipramine, an antidepressant. Synonyms: (2S,3S,4S,5R)-6-((3-(10,11-Dihydro-5H-dibenzo[b,f]azepin-5-yl)-2-methylpropyl)dimethylammonio)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate; N-β-D-Glucopyranuronosyl-10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanaminium Inner Salt. Grades: > 95%. CAS No. 165602-84-6. Molecular formula: C26H34N2O6. Mole weight: 470.57.
Trimipramine N-oxide
A metabolite of Trimipramine. Synonyms: 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine N-Oxide; 5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine N-Oxide. Grades: > 95%. CAS No. 14171-70-1. Molecular formula: C20H26N2O. Mole weight: 310.44.
Tris (acetonitrile) pentamethylcyclopentadienyl cobalt(III) hexafluoroantimonate
. Uses: Transition metal catalysts. Synonyms: Cobalt(2+), tris(acetonitrile)[(1,2,3,4,5-η)-1,2,3,4,5-pentamethyl-2,4-cyclopentadien-1-yl]-, (OC-6-11)-hexafluoroantimonate(1-) (1:2); [Cp*Co(MeCN)3] [SbF6]2; Tris (acetonitrile) (pentamethylcyclopentadienyl)cobalt bis(hexafluoroantimonate). Grades: ≥95%. CAS No. 1642132-26-0. Molecular formula: C16H24CoN3.2F6Sb. Mole weight: 788.82.
Trofinetide
Trofinetide is a NMDA antagonist under the development of Neuren Pharmaceuticals. It is an analogue of the neuropeptide (1-3) IGF-1, which is a simple tripeptide with sequence Gly-Pro-Glu formed by enzymatic cleavage of the growth factor IGF-1 within the brain. Phase II clinical trials against Fragile X syndrome and Rett syndrome are on-going. Uses: Brain injuries; fragile x syndrome; rett syndrome. Synonyms: NNZ-2566; NNZ 2566; NNZ2566; Trofinetide; ((S)-1-glycyl-2-methylpyrrolidine-2-carbonyl)-L-glutamic acid. Grades: 98%. CAS No. 853400-76-7. Molecular formula: C13H21N3O6. Mole weight: 315.32.
(Trp4)-Octreotide
(Trp4)-Octreotide is an impurity of octreotide. Synonyms: H-D-Phe-Cys-Phe-Trp-Lys-Thr-Cys-L-threoninol (Disulfide bridge: Cys2-Cys7); H-D-Phe-Cys-Phe-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-phenylalanyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grades: ≥95%. Molecular formula: C49H66N10O10S2. Mole weight: 1019.26.
(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent and selective NK-3 receptor antagonist demonstrated by antagonizing neurokinin B on the NK-3 receptor in the rat portal vein. Synonyms: R486; L-α-Aspartyl-L-seryl-L-phenylalanyl-L-tryptophyl-β-alanyl-L-leucyl-L-methioninamide; L-Methioninamide, L-α-aspartyl-L-seryl-L-phenylalanyl-L-tryptophyl-β-alanyl-L-leucyl-; H-Asp-Ser-Phe-Trp-β-Ala-Leu-Met-NH2. Grades: ≥95%. CAS No. 132041-95-3. Molecular formula: C41H57N9O10S. Mole weight: 868.01.
Trp-Arg
Tryptophanyl-arginine is a dipeptide composed of tryptophan and arginine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Arginine, L-tryptophyl-; tryptophanyl-arginine; L-tryptophyl-L-arginine; (S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-5-guanidinopentanoic acid. Grades: ≥95% by HPLC. CAS No. 88831-09-8. Molecular formula: C17H24N6O3. Mole weight: 360.41.
Trp-His-Trp-Leu-Gln-Leu
Synonyms: α1-Mating factor fragment 1-6. CAS No. 65418-88-4. Molecular formula: C45H59N11O8. Mole weight: 882.02.
TRV-120027 acetate, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV-120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV-120027 has the potential for acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine acetic acid; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, acetate (1:1); TRV 027 acetate; TRV 120027 acetate; TRV120027 acetate. Grades: ≥95%. Molecular formula: C45H71N13O12. Mole weight: 986.14.
TRV-120027 TFA
TRV120027 TFA, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV120027 TFA inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 TFA has the potential for the acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.TFA; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine trifluoroacetate; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, trifluoroacetate (1:1); TRV 027 trifluoroacetate; TRV 120027 trifluoroacetate; TRV120027 trifluoroacetate; TRV120027 TFA; TRV 120027 TFA. Grades: 99%. Molecular formula: C45H68F3N13O12. Mole weight: 1040.10.
Tryptanthrin
Tryptanthrin is a potent inhibitor of Cox-2, IDO and NOS II produced by the strain of Candida lipolytica CBS2070 2072 and it has the effect of resisting gram positive bacteria. Synonyms: Tryptanthrine; NSC 349447; Indolo(2,1-b)quinazoline-6,12-dione (8CI)(9CI). Grades: ≥98%. CAS No. 13220-57-0. Molecular formula: C15H8N2O2. Mole weight: 248.24.
Tryptophanyl-glutamine
Tryptophanyl-glutamine is a dipeptide composed of tryptophan and glutamine. Synonyms: Trp-Gln. CAS No. 175027-12-0. Molecular formula: C16H20N4O4. Mole weight: 332.35.
Tryptophanyl-phenylalanine
Tryptophanyl-phenylalanine is a dipeptide composed of tryptophan and phenylalanine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: H-WF-OH; L-tryptophyl-L-phenylalanine; Trp-Phe; (S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-phenylpropanoic acid; L-Phenylalanine, L-tryptophyl-; L-Trp-L-Phe; L-Trp-L-Phe-OH. Grades: ≥95%. CAS No. 6686-2-8. Molecular formula: C20H21N3O3. Mole weight: 351.40.
T-(S)-GNA phosphoramidite
T-(S)-GNA phosphoramidite is a crucial building block in the synthesis of oligonucleotides used to treat various diseases such as cancer, viral infections, and genetic disorders. It is used to specifically modify the nucleotides of the oligonucleotide, enhancing its therapeutic potential and specificity. By utilizing this product, researchers can improve the efficacy and selectivity of their oligonucleotide-based therapies. Synonyms: (S)-1-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propan-2-yl (2-cyanoethyl) diisopropylphosphoramidite; 1-[(S)-2-[[(Diisopropylamino)(2-cyanoethoxy)phosphino]oxy]-3-[(4,4'-dimethoxytrityl)oxy]propyl]thymine. Grades: ≥98%. CAS No. 168332-13-6. Molecular formula: C38H47N4O7P. Mole weight: 702.78.
TT-232 TFA
TT-232 TFA is a somatostatin analog that acts as a peptide agonist for sst1/sst4 somatostatin receptors. TT-232 TFA inhibits tyrosine kinase activity in human colon tumor cell lines. TT-232 TFA was shown to suppress proliferation and induce apoptosis in a pancreatic tumor cell line. Synonyms: H-D-Phe-Cys-Tyr-D-Trp-Lys-Cys-Thr-NH2.TFA (Disulfide bridge: Cys2-Cys6); D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-cysteinyl-L-threoninamide (2->6)-disulfide trifluoroacetic acid; CAP 232 TFA; TLN 232 TFA; TT 2-32 TFA. Grades: ≥95%. CAS No. 2703745-48-4. Molecular formula: C45H58N10O9S2.C2HF3O2. Mole weight: 1061.16.
Tuftsin 3TFA
Tuftsin is a tetrapeptide located in the Fd fragment of the gamma-globulin molecule. Tuftsin is a macrophage/microglial activator. Synonyms: L-Arginine, N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-, tris(trifluoroacetate) (salt); Acetic acid, trifluoro-, compd. with N2-[1-(N2-L-threonyl-L-lysyl)-L-prolyl]-L-arginine (3:1); H-Thr-Lys-Pro-Arg-OH.3TFA; L-threonyl-L-lysyl-L-prolyl-L-arginine trifluoroacetic acid; TKPR.3TFA. Grades: ≥95%. CAS No. 81019-03-6. Molecular formula: C21H40N8O6.3C2HF3O2. Mole weight: 842.66.
Tumidulin
It is produced by the strain of Ramalina spp. Synonyms: Methyl 3,5-dichlorolecanorate; Benzoic acid, 3,5-dichloro-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-5-methylphenyl ester. Grades: ≥98%. CAS No. 4382-39-2. Molecular formula: C17H14Cl2O7. Mole weight: 401.19.
Tylosin monotartrate
Tylosin tartrate is a macrolide antibiotic produced by Streptomyces. Tylosin tartrate is an antimicrobial for gram-positive bacteria and mycoplasma. It can be used to prevent and treat respiratory diseases such as mycoplasma pneumonia, pleuropneumonia, swine pneumonia, Haemophilus parasuis, streptococcus suis, and other tissue infections. Synonyms: Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1); Tylosin, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt); Tylosin, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt); Pharmasin; Tylan Injectable; Tylan Soluble; Tylosin tartrate. Grades: >98%. CAS No. 74610-55-2. Molecular formula: C50H83NO23. Mole weight: 1066.19.