BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
| Product | Description | |
|---|---|---|
| 5-Methylcytidine 5'-Triphosphate Trisodium Salt | 5-Methylcytidine 5'-Triphosphate is a trisodium triphosphate salt of 5-Methylcytidine a derivative of Cytidine, found in ribonucleic acids of animals, plants and bacteria. 5-Methylcytidine is a nucleoside found in liver emulsion that can inhibit the growth of spontaneous tumors of mammary gland origin in mice. Synonyms: 5-Methylcytidine 5'-(Tetrahydrogen Triphosphate) Trisodium Salt; 5-Methyl-CTP Trisodium Salt. Molecular formula: C10H15N3Na3O14P3. Mole weight: 563.13. |  |
| 5'-O-(4,4'-Dimethoxytrityl)-3-formylindole-2'-deoxyriboside | 5'-O-(4,4'-Dimethoxytrityl)-3-formylindole-2'-deoxyriboside is a valuable compound widely used in the biomedical industry serving as a crucial building block in the research and development of nucleoside analogs and can be utilized in drug development against various diseases, including cancers and viral infections. Synonyms: 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-1H-indole-3-carbaldehyde; 1-[5-O-(4,4'-Dimethoxytrityl)-2-deoxy-beta-D-erythro-pentofuranosyl]-1H-indole-3-carbaldehyde. Grades: ≥95%. CAS No. 460355-04-8. Molecular formula: C35H33NO6. Mole weight: 563.64. | |
| 5'-O-DMT-2'-O-TBDMS-5-Methy-L-Uridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-5-Methyl-L-Uridine 3'-CE phosphoramidite is a DNA synthesis building block with a 5'-dimethoxy trityl group. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5-Methyl-5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-uridine-3'-cyanoethyl phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-2-O-(tert-butyl-dimethyl-silyl)-1-deoxy-1-thymin-1-yl-beta-D-ribo-pentofuranose; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-O-[dimethyl (2-methyl-2-propanyl)silyl]-5-methyluridine; DMT-2'-O-TBDMS-5-Me-rU Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 159639-78-8. Molecular formula: C46H63N4O9PSi. Mole weight: 875.09. | |
| 5'-O-DMT-thymidine 3'-CE phosphoramidite | 5'-O-DMT-thymidine 3'-CE phosphoramidite is an immensely critical compound employed in the solid-phase synthesis of oligonucleotides, the building blocks of DNA. The chemical is a phosphoramidite derivative of thymidine, which dutifully incorporates into the growing strand of DNA during synthesis, and crucially, in turn, dictates the eventual structure of the resultant chemical entity. As the leading-edge compound known to have tremendous potential in treating an array of viral infections and genetic diseases, this compound has opened new doors of discovery that were previously deemed unattainable. Synonyms: dT CEP; 5'-Dimethoxytrityl-2'-deoxyThymidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: ≥ 98%. CAS No. 98796-51-1. Molecular formula: C40H49N4O8P. Mole weight: 744.83. | |
| 5-S-Methyl-5-thio-D-xylose | 5-S-Methyl-5-thio-D-xylose is a highly potent and dynamic compound intricately modulating viral replication and impeding cancer progression through exquisite precision. It emerges as a formidable anti-viral and anti-neoplastic agent. Synonyms: (2R,3R,4S)-2,3,4-Trihydroxy-5-methylsulfanylpentanal. CAS No. 53458-58-5. Molecular formula: C6H12O4S. Mole weight: 180.22. | |
| 5-Vinyl-UTP | 5-Vinyl-UTP is a vital tool in the biomedical industry used for the research and development of modified RNA molecules. This compound is commonly employed in research to investigate RNA tertiary structures, RNA-protein interactions and RNA enzymatic activities. Furthermore, 5-Vinyl-UTP facilitates the study of RNA-related diseases and the development of potential RNA-based therapeutics for a range of disorders. Grades: ≥ 95% by HPLC. Molecular formula: C11H17N2O15P3 (free acid). Mole weight: 510.18 (free acid). | |
| 6-Azauracil | 6-Azauracil inhibits enzymes in nucleoside synthesis and depletes the intracellular GTP/UTP pool. It is being used to identify mutations in transcriptional elongation machinery, as well as mutations in a variety of other pathways. Uses: Inhibits enzymes in nucleoside synthesis and depletes the intracellular gtp/utp pool. Synonyms: 2H-1,2,4-triazine-3,5-dione. Grades: ≥ 98 %. CAS No. 461-89-2. Molecular formula: C3H3N3O2. Mole weight: 113.07. | |
| 6-Chloro-3-indolyl phosphate p-toluidine salt | 6-Chloro-3-indolyl phosphate p-toluidine salt is an indispensable recompound in the biomedical sphere, holding applications encompasses the colorimetric appraisal of alkaline phosphatase activity across diverse domains. Essential in the study of alkaline phosphatase-related ailments, this compound facilitates meticulous identification and comprehensive analysis. Synonyms: 6-Chloro-3-indolyl phosphate p-toluidine salt; Salmon phosphate; 154201-84-0; p-Toluidine 6-chloro-1H-indol-3-yl phosphate; 6-Chloro-3-indoxyl phosphate, p-toluidine salt; (6-chloro-1H-indol-3-yl) dihydrogen phosphate; 4-methylaniline; (6-chloro-1H-indol-3-yl) hydrogen phosphate; (4-methylphenyl)azanium; 6-Chloro-3-indolyl phosphate, p-toluidine salt; 6-Chloro-3-indolyl-phosphate p-toluidine salt; SCHEMBL9299192; DTXSID10165558; Salmon-phosphate p-toluidine salt; AMY41655; MFCD00216690; AKOS015911346; FD10021; CS-0324256; C-5100; A906756; 4-methylaniline; [(6-chloro-1H-indol-3-yl)oxy]phosphonic acid; 6-Chloro-3-indolyl phosphate p-toluidine salt, >=98.0% (HPLC); 1H-Indol-3-ol, 6-chloro-, dihydrogen phosphate (ester), compd. with 4-methylbenzenamine (1:1) (9CI). CAS No. 159954-33-3. Molecular formula: C8H6ClNO4P.C7H10N. Mole weight: 354.73. | |
| 6-cPe-5'-AMP | 6-cPe-5'-AMP is an analogue of AMP and a potential metabolite of 6-cPe-ATP and 6-cPe-ADP. Grades: ≥ 97 % by HPLC. CAS No. 117778-38-8. Molecular formula: C15H22N5O7P (free acid). Mole weight: 415.3 (free acid). | |
| 6-Hydroxy-DL-DOPA | 6-Hydroxy-DL-DOPA is an allosteric inhibitor of RAD52 that suppresses RAD52 binding to single strand DNA binding domains (IC50 = 1.1 μM). 6-Hydroxy-DL-DOPA inhibits proliferation of BRCA-deficient cancer cells in vitro. Synonyms: 2,5-Dihydroxy-DL-tyrosine; 6-Hydroxydopa; 6-Ohdopa; 2,5-Dihydroxytyrosine; 2,4,5-Trihydroxyphenylalanine. CAS No. 21373-30-8. Molecular formula: C9H11NO5. Mole weight: 213.19. | |
| 6-Hydroxy Melatonin | 6-Hydroxy Melatonin is a metabolite of Melatonin. Uses: Cardiotonic agents. Synonyms: N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide; 6-Hydroxy-N-acetyl-5-methoxytryptamine. Grades: > 95%. CAS No. 2208-41-5. Molecular formula: C13H16N2O3. Mole weight: 248.28. | |
| 6-methyldibenzo[c,f][1,2]thiazepin-11(6H)-one 5,5-dioxide | An impurity of Tianeptine, which is a selective serotonin reuptake enhancer (SSRE) used for treating major depressive episodes. Synonyms: Dibenzo[c,f][1,2]thiazepin-11(6H)-one, 6-methyl-, 5,5-dioxide; 10-methyl-9; SCHEMBL19194634; DTXSID901180125; 6-methyl-5,5-dioxobenzo[c][1,2]benzothiazepin-11-one; 10-methyl-9|E?-thia-10-azatricyclo[9.4.0.0?,?]pentadeca-1(11),3(8),4,6,12,14-hexaene-2,9,9-trione. CAS No. 26638-46-0. Molecular formula: C14H11NO3S. Mole weight: 273.31. | |
| 6-Sulfatoxy Melatonin Sodium Salt | 6-Sulfatoxy Melatonin Sodium Salt is a metabolite of Melatonin. Synonyms: N-[2-[5-Methoxy-6-(sulfooxy)-1H-indol-3-yl]ethyl]acetamide Sodium; 6-(Sulfonyloxy)melatonin Sodium; 6-Hydroxymelatonin Sulfate Sodium; 6-Sulphatoxymelatonin Sodium. Grades: > 95%. CAS No. 76290-78-3. Molecular formula: C13H15N2O6SNa. Mole weight: 350.32. | |
| 7,8-dihydro biopterin | 7,8-dihydro biopterin is a precursor of BH4 synthesis and a noncompetitive inhibitor of GCH-I (GTP cyclohydrolase I). It is the reduced form of Biopterin. Synonyms: 7,8-Dihydro-L-biopterin; 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; L-erythro-7,8-Dihydrobiopterin; L-erythro-Dihydrobiopterin. Grades: > 95%. CAS No. 6779-87-9. Molecular formula: C9H13N5O3. Mole weight: 239.24. | |
| 7-Epi Clindamycin 2-Phosphate Ammonium Salt | Clindamycin impurity. Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galactooctopyranoside 2-(Dihydrogen Phosphate) Monoammonium Salt. Molecular formula: C18H37ClN3O8PS. Mole weight: 521.99. | |
| 7-O-Acetyl-N-acetylneuraminic acid | 7-O-Acetyl-N-acetylneuraminic acid is a highly potent compound, showcasing remarkable efficacy in studying diverse viral infections owing to its profound antiviral properties. Furthermore, it assumes a pivotal role in the research and development of drugs targeting maladies induced by pathogenic entities like influenza viruses and sialylated bacteria. Synonyms: Neu5,7Ac2. CAS No. 18529-63-0. Molecular formula: C13H21NO10. Mole weight: 351.31. | |
| 8-Hydroxyguanosine | It is a representative metabolite derived by the oxidation of Guanosine (G) and is regarded as a marker of oxidative stress in the cells. It is also an RNA adduct. Uses: Adjuvants, immunologic. Synonyms: 2-Amino-9-β-D-ribofuranosyl-purine-6,8(1H,9H)-dione; 8-OHG; 8-Oxo-7,8-dihydroguanosine; 8-Oxoguanosine; NSC 90393; 2-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-8-hydroxy-1H-purin-6(9H)-one; 7,8-dihydro-8-oxoguanosine. Grades: ≥97%. CAS No. 3868-31-3. Molecular formula: C10H13N5O6. Mole weight: 299.24. | |
| 9,10-Anthraquinone-2,7-disulfonic acid | Synonyms: 9,10-dihydro-9,10-dioxo-7-anthracenedisulfonicacid; 2,7-ANTHRAQUINONE DISULFONIC ACID; 9,10-ANTHRAQUINONE-2,7-DISULFONIC ACID; 9,10-dioxoanthracene-2,7-disulphonic acid; 9,10-dioxo-9,10-dihydroanthracene-2,7-disulfonic acid; 2,7-Disulfoanthraquinone; 9,10-Dihy. CAS No. 84-49-1. Molecular formula: C14H8O8S2. Mole weight: 368.34. | |
| 9-Deoxo-9a-aza-9a-homo 4'-Keto Erythromycin A | 2R, ?3S, ?4R, ?5R, ?8R, ?10R, ?11R, ?12S, ?13S, ?14R)?-13-[(2, ?6-Dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranos-4-ulos-1-yl)?oxy]?-2-ethyl-3, ?4, ?10-trihydroxy-3, ?5, ?8, ?10, ?12, ?14-hexamethyl-11-[[3, ?4, ?6-trideoxy-3-(dimethylamino)?-β-D-xylo-hexopyranosyl]?oxy]?-1-oxa-6-azacyclopentadecan-15-one is an intermediate in synthesizing Tulathromycin A-d7, a labeled analogue of Triamilide, which is an antibiotic for treatment of bovine and porcine respiratory disease. Exists as an equilibrium mixture of two isomeric forms, Tulathromycin A (90%) and B (10%). Antibacterial. Synonyms: 2R, ?3S, ?4R, ?5R, ?8R, ?10R, ?11R, ?12S, ?13S, ?14R)?-13-[(2, ?6-Dideoxy-3-C-methyl-3-O-methyl-α-L-erythro-hexopyranos-4-ulos-1-yl)?oxy]?-2-ethyl-3, ?4, ?10-trihydroxy-3, ?5, ?8, ?10, ?12, ?14-hexamethyl-11-[[3, ?4, ?6-trideoxy-3-(dimethylamino)?-β-D-xylo-hexopyranosyl]?oxy]?-1-oxa-6-azacyclopentadecan-15-one. CAS No. 270583-32-9. Molecular formula: C37H68N2O12. Mole weight: 732.94. | |
| 9-Fluorenylmethyl carbazate | 9-Fluorenylmethyl carbazate may be used as a derivatization reagent to derivatize progesterone for high-performance liquid chromatography, in the analysis of progesterone, 17-hydroxyprogesterone and other 3-keto steroids. It may also be used as one of the fluorescence labeling agent for high-performance liquid chromatography determination of neutral and amino monosaccharides in glycoproteins by ultraviolet and fluorescence detection. Synonyms: Fmoc-hydrazine; (9H-Fluoren-9-yl)methyl hydrazinecarboxylate; Fmoc-NHNH2; [(9H-Fluoren-9-ylmethoxy)carbonyl]hydrazine; Carbazic Acid 9-Fluorenylmethyl Ester; N-[(9H-fluoren-9-ylmethoxy)-carbonyl]-hydrazine; 9h-fluoren-9-ylmethyl hydrazinecarboxylate; 9-Fluorenylmethylcarbazate; Hydrazinecarboxylic acid, 9H-fluoren-9-ylmethyl ester; AK-25841; Carbazic acid 9H-fluorene-9-ylmethyl ester. Grades: 98 % (HPLC). CAS No. 35661-51-9. Molecular formula: C15H14N2O2. Mole weight: 254.28. | |
| 9(Z),11(E),13(E)-Octadecatrienoic acid | 9(Z),11(E),13(E)-Octadecatrienoic acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. Synonyms: α-Eleostearic acid; α-ESA; LAF 237; alpha-Eleostearic acid. Grades: ≥95%. CAS No. 506-23-0. Molecular formula: C18H30O2. Mole weight: 278.4. | |
| A01 | A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Study showed that it potentiated BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells. Synonyms: Smurf1-IN-A01; Smurf1INA01; Smurf1 IN A01; Smurf1 inhibitor A01; Smurf1-inhibitor-A01; A01; A 01; A-01; [4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone; SMURF1 inhibitor A01. Grades: ≥98% by HPLC. CAS No. 1007647-73-5. Molecular formula: C22H20ClF3N4O3S. Mole weight: 512.93. | |
| A 1120 | A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes. Synonyms: A-1120; A1120; 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid. Grades: ≥99% by HPLC. CAS No. 1152782-19-8. Molecular formula: C20H19F3N2O3. Mole weight: 392.37. | |
| A-1155463 | A-1155463, an effective and selective BCL-XL inhibitor, has been studied to have probable effect in restraining the growth of small cell lung cancer xenograft tumors. IC50: <0.01 nM (Ki). Uses: A-1155463 is an effective and selective bcl-xl inhibitor that has been studied to have probable effect in restraining the growth of small cell lung cancer xenograft tumors. Synonyms: CHEMBL3342332; A-1155463; A 1155463; A1155463; SCHEMBL2501550; BDBM50030754; CS-5398; HY-19725; CS 5398; HY 19725; CS5398; HY19725. Grades: 98%. CAS No. 1235034-55-5. Molecular formula: C35H32FN5O4S2. Mole weight: 669.79. | |
| A-1210477 | A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over other Bcl-2 family members. Synonyms: A 1210477; A1210477; Abbvie Mcl-1 Inhibitor; 7-(5-((4-(4-(N,N-Dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid. Grades: 98%. CAS No. 1668553-26-1. Molecular formula: C46H55N7O7S. Mole weight: 850.04. | |
| A 127722 | A 127722 is a potent and selective ETA endothelin receptor antagonist (IC50 = 0.11 nM and 98 nM for human ETA and ETB receptors, respectively). It attenuates hypoxia-induced pulmonary hypertension in rats. Synonyms: A-127722; A127722; rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid. Grades: ≥98% by HPLC. CAS No. 195704-72-4. Molecular formula: C29H38N2O6. Mole weight: 510.62. | |
| A12B4C3 | A12B4C3 is a potent and selective inhibitor of polynucleotide kinase/phosphatase (PNKP) (IC50 = 60 nM), a DNA repair enzyme. A12B4C3 is inactive to calcineurin, protein PP-1 or APTX. Synonyms: A12B4C3; A-12-B-4-C-3; A 12 B 4 C 3; A12 B4 C3; A12-B4-C3; 4a,7a-Dihydro-2-(1-hydroxyundecyl)-1-[(4-nitrophenyl)amino]-6-phenyl-1H-pyrrolo[3,4-b]pyridine-5,7(2H,6H)-dione. Grades: ≥98% by HPLC. CAS No. 1005129-80-5. Molecular formula: C30H38N4O5. Mole weight: 534.65. | |
| a1,2-Galactobiosyl b-methyl glycoside | The product, a1,2-Galactobiosyl b-methyl glycoside, is a valuable compound primarily employed in the biomedical industry. It serves as a crucial ingredient in the development of novel drugs for treating various diseases. Synonyms: Gala1-2Galb1-O-Me. Grades: 95%. Molecular formula: C13H24O11. Mole weight: 356.32. | |
| a1,2-Mannobiose-BSA | | |
| A-1331852 | A-1331852, a substituted benzothiazole, is a high affinity BH3 mimetic Ligand of BCL protein BCL-XL (Ki ≤ 10 pM). A-1331852 is an orally apoptosis-inducing agent that may have potential as improved cancer therapeutics. Synonyms: 3-(1-(((3r,5r,7r)-adamantan-1-yl)methyl)-5-methyl-1H-pyrazol-4-yl)-6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)picolinic acid; A-1331852; A 1331852; A1331852; ABT-263; ABT-199; ABT 199; ABT199. CAS No. 1430844-80-6. Molecular formula: C38H38N6O3S. Mole weight: 658.81. | |
| a1-3[a1-6]a1-6[a1-3]Mannopentaose | Mannopentaose is a potent antifungal compound, offering an exquisite capability to impede the expansion of specific fungi. Synonyms: α1-3,α1-3,α1-6 Mannopentaose; Mana3[Mana6]Mana6[Mana3]Man; O-α-D-Mannopyranosyl-(1?3)-O-[α-D-mannopyranosyl-(1?6)]-O-α-D-mannopyranosyl-(1?6)-O-[α-D-mannopyranosyl-(1?3)]-D-mannose; Man5; α3,α6-mannopentaose. Grades: ≥85%. CAS No. 112828-69-0. Molecular formula: C30H52O26. Mole weight: 828.72. | |
| a1-3,a1-6-Mannotriose-BSA | | |
| a1-3-Galactobiose-biotin | a1-3-Galactobiose-biotin is an essential constituent assuming a pivotal role in the research of ailments such as cancer, infections and autoimmune dysfunctions. Synonyms: Gala1-3Galb-sp-biotin. Molecular formula: C22H36N2O13S. Mole weight: 568.59. | |
| a1-3 Galactobiosyl b-methyl glycoside | a1-3 Galactobiosyl b-methyl glycoside is a remarkable compound encompassing a b-methyl glycoside structure intertwined with a1-3 galactobiosyl moiety. Synonyms: α1-3 Galactobiosyl β-methyl glycoside; Galα1-3Galβ1-O-Me. Molecular formula: C13H24O11. Mole weight: 356.32. | |
| a1,3-Galactobiosyl b-methyl glycoside | a1,3-Galactobiosyl b-methyl glycoside is regarded as a fundamental instrument in compound, enabling elucidation of the intricate mechanisms underlying distinct glycosylation patterns. Furthermore, it representing an invaluable asset in the realm of glycoside research and development and the investigation of their manifold impacting on cellular signaling pathways, particularly those intertwined with galactosidase deficiency and galactosemia. Synonyms: Gala1-3Galb1-O-Me. Grades: 95%. Molecular formula: C13H24O11. Mole weight: 356.32. | |
| a1,3-Mannobiose-BSA | | |
| a1,4-Mannobiose-BSA | | |
| a1,6-Mannobiose-BSA | | |
| A-19009 | A-19009 is a peptide antibiotic produced by Streptomyces collinus A-19009. It mainly has antifungal and vaginal trichomonas activity. Synonyms: Antibiotic A 19009; N-(N(3)-Fumaramoyl-2,3-diaminopropanoyl)alanine; L-Alanine, N-L-alanyl-3-((4-amino-1,4-dioxo-2-butenyl)amino)-, (E)-. CAS No. 87768-72-7. Molecular formula: C10H16N4O5. Mole weight: 272.26. | |
| A-192621 | A-192621 is a selective antagonist at endothelin ETB receptor with more effective than IRL-2500 in blocking IRL-1620-induced vasoconstriction, but both augmented constrictor responses to ET-1. Synonyms: (2R,3R,4S)-4-(1,3-benzodioxol-5-yl)-1-[2-(2,6-diethylanilino)-2-oxoethyl]-2-(4-propoxyphenyl)pyrrolidine-3-carboxylic acid; (2R-(2alpha,3beta,4alpha)-4-(1,3-benzodioxol-5-yl)-1-(2-(2,6-diethylphenyl)amino)-2-oxoethyl)-2-(4-propoxyphenyl)-3-pyrrolidinecarboxylic acid; A 192621; A-192621; A192621. Grades: >98%. CAS No. 195529-54-5. Molecular formula: C33H38N2O6. Mole weight: 558.675. | |
| A 196 | A 196 is a potent and selective inhibitor of SUV420H1/H2 (IC50 = 25 and 144 nM, respectively) with 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. It was shown to inhibit the di- and tri-methylation of H4K20me in multiple cell lines (IC50 < 1 μM). Synonyms: SGC A-196; SGC A 196; SGC A196; SGC-A-196; SGCA196; A-196; A 196; A196; 6,7-Dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine. Grades: ≥98% by HPLC. CAS No. 1982372-88-2. Molecular formula: C18H16Cl2N4. Mole weight: 359.25. | |
| A1B1 hydrochloride | A1B1 hydrochloride is a potent and orally-available chemokine CCR1 antagonist. Synonyms: N-[5-chloro-2-[(E)-3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-3-oxoprop-1-enyl]phenyl]acetamide hydrochloride. Grades: 99%. Molecular formula: C23H25ClFN3O2.HCl. Mole weight: 466.38. | |
| A1 Barrigenyl pentaacetate | Synonyms: Olean-12-ene-3β, 15α, 16α, 22α, 28-pentol, pentaacetate (8CI); Barrigenol A1 pentaacetate; Olean-12-ene-3,15,16,22,28-pentol, pentaacetate, (3β, 15α, 16α, 22α)- (9CI). CAS No. 17991-60-5. Molecular formula: C40H60O10. Mole weight: 700.9. | |
| A1F Glycan, 2-AA labelled | A1F Glycan, 2-AA labelled is a specialized product commonly used in the research and development of novel drugs used for the treatment of various types of cancers and autoimmune diseases. This glycan is a modified form of A1F, which has been labelled with a 2-Aminobenzoic acid (2-AA) to enhance its ability to bind to specific receptors and increases bioavailability. Its unique properties make it an essential tool for scientists studying the mechanisms of certain diseases and developing targeted therapies. | |
| A1F Glycan, 2-AB labelled | | |
| A1F N-Glycan | A1F N-Glycan, the versatile biomolecule employed by the biomedical industry, is the key player in the in-depth scrutiny and diagnosis of diverse disorders - think cancer, Alzheimer's, and rheumatoid arthritis. Its multifaceted involvement in cell signaling pathways has made it a go-to diagnostic marker in countless clinical settings. Furthermore, the therapeutic potential of A1F N-Glycan has not gone unexploited; it forms the crux of several drug formulations aimed at combating these afflictions. Synonyms: Monosialo (2,6), fucosylated biantennary (A1F); A1F glycan; FA2G2S1 Glycan; Mono-sialylated, galactosylated, core-fucosylated, bi-antennary N-linked glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), mono-sialyl-bis(galactosyl-N-acetylglucosaminyl); NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2Fuc. Grades: ≥90%. CAS No. 571188-30-2. Molecular formula: C79H131N5O58. Mole weight: 2078.88. | |
| A1 Glycan, 2-AA labelled | A1 Glycan, 2-AA labelled, an indispensable instrument for exploring the intricacies of glycans linked to multifarious illnesses, encompassing cancer, Alzheimer's, and autoimmune disorders, is an asset to biomedical research. An integral part of comprehending the biological underpinnings and workings of these ailments, this product is vital in developing efficacious therapies. | |
| A1 Glycan, 2-AB labelled | | |
| A1 N-Glycan | A1 N-Glycan is a versatile and Indispensable compound orchestrating numerous vital biological phenomena encompassing the domains of cell adhesion, immune response modulation and the enigmatic journey of disease progression. Synonyms: Monosialo (2,6), biantennary (A1); A1 glycan; A2G2S1 N-Glycan; NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2; Mono-sialylated, galactosylated, bi-antennary N-linked glycan. Grades: ≥90%. CAS No. 145211-79-6. Molecular formula: C73H121N5O54. Mole weight: 1932.74. | |
| A21459 A | A21459 A is a cyclic peptide antibiotic produced by Actinoplanes sp. It has anti-clostridium (MIC 0.03-8 μg/mL) and mycoplasma (MIC 2 μg/mL) activity. Synonyms: A21459A. Molecular formula: C41H46N10O8S. Mole weight: 838.93. | |
| A21459 B | A21459 B is a cyclic peptide antibiotic produced by Actinoplanes sp. It has anti-clostridium (MIC 0.03-8 μg/mL) and mycoplasma (MIC 2 μg/mL) activity. Synonyms: A21459B. Molecular formula: C40H44N10O8S. Mole weight: 824.90. | |
| A23187 Ca-Mg | A23187 Ca-Mg, the calcium-magnesium salt of A23187, has been found to be a Ca2+ ionophore and shows pro-inflammatory and allergic activities. Uses: Used in cell activation experiments when calcium dose-response data are not required. Synonyms: Calcimycin calcium magnesium salt; Antibiotic A23187 calcium magnesium salt; Ionophore A23187 calcium magnesium salt. Grades: ≥99%. Molecular formula: (C29H36N3O6)2Mg.(C29H36N3O6)2Ca. Mole weight: 2154.87. | |
| A-25822 A | A-25822 A is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. Synonyms: A-25822A. CAS No. 50686-99-2. Molecular formula: C30H49NO. Mole weight: 439.71. | |
| A-25822 B | A-25822 B is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. Synonyms: 15-Azasterol; 15-Aza-24-methylene-8,14-cholestadiene-3beta-ol; Homoazasterol. CAS No. 50686-98-1. Molecular formula: C28H45NO. Mole weight: 411.66. | |
| A-25822 L | A-25822 L is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. CAS No. 50687-02-1. Molecular formula: C28H43NO2. Mole weight: 425.64. | |
| A-25822 M | A-25822 M is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. CAS No. 50886-40-3. Molecular formula: C30H47NO2. Mole weight: 453.70. | |
| A-25822 N | A-25822 N is an azasteroid antibiotic produced by Geotrichum flavobrienneum. It has anti-fungal activity, and the MIC for fungi such as Candida albicans, Cryptococcus neoformans, Trichophyton mentacea, Phytoplastria, Saccharomyces cerevisiae, Saccharomyces cerevisiae, Microsporum, etc. is 0.321-1.25 μg/mL. Antibacterial activity is weak. Synonyms: Antibiotic A-25822N. CAS No. 50687-00-8. Molecular formula: C28H43NO. Mole weight: 409.65. | |
| A-26771 B | A-26771 B is an antibiotic produced by Penicillum turbatum. Activity against gram-positive bacteria. Synonyms: A 26771B. Grades: >98%. CAS No. 56448-20-5. Molecular formula: C20H30O7. Mole weight: 382.45. | |
| A-26771 C | A-26771 C is an antibiotic produced by Penicillum turbatum. It has anti-gram-positive bacteria and several viral activities. Synonyms: A26771C. CAS No. 52748-85-3. Molecular formula: C14H16N2O3S4. Mole weight: 388.55. | |
| A-26771 E | A-26771 E is an antibiotic produced by Penicillum turbatum. Activity against gram-positive bacteria. Synonyms: FR 106969; 2,5-Piperazinedione, 3,6-bis(methylthio)-1,4-dimethyl-3-(hydroxymethyl)-6-(phenylmethyl)-. CAS No. 50655-20-4. Molecular formula: C16H22N2O3S2. Mole weight: 354.49. | |
| A2793 | A2793 is a dual inhibitor of TWIK-related spinal cord potassium channel (TRESK/K2P18/KCNK18) and TASK-1 (KCNK3) with IC50 of 6.8 μM for mouse TRESK. Synonyms: Ethyl [(5-Chloroquinolin-8-yl)oxy]acetate. CAS No. 88349-90-0. Molecular formula: C13H12ClNO3. Mole weight: 265.69. | |
| A 28695 B | A28695 is a polyether antibiotic produced by Streptomyces albus NRRL 3883. It has anti-bacterial, anti-fungal, anti-virus and insecticidal activities, and can prevent coccidia infections in poultry and rabbits. Synonyms: Antibiotic A-28695 B. Grades: >98%. CAS No. 42617-35-6. Molecular formula: C48H82O17. Mole weight: 931.15. | |
| A 286982 | A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 = 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays, respectively). Synonyms: A-286982; A 286982; A286982; (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one. Grades: ≥99% by HPLC. CAS No. 280749-17-9. Molecular formula: C24H27N3O4S. Mole weight: 453.55. | |
| A2AR-agonist-1 | A2AR-agonist-1 is a potent A2AR (Ki = 4.39) and ENT1(Ki = 3.47 ) agonist. Uses: A potent a2ar and ent1 agonist. Synonyms: N-(2-(1H-indol-3-yl)ethyl)-Adenosine. Grades: ≥98%. CAS No. 41552-95-8. Molecular formula: C20H22N6O4. Mole weight: 410.43. | |
| A2B N-Glycan | A2B N-Glycan is a fundamental constituent employed in dissecting intricate glycosylation arrangements. It assumes a pivotal function in developing the formulation of therapeutics directed towards a myriad of ailments such as neoplasms, neurodegenerative maladies like Alzheimer's and immune system dysfunctions. Synonyms: Sialo, bisected, biantennary N-linked glycan. | |
| A2B receptor antagonist 1 | A potent antagonist of A2B adenosine receptor. Synonyms: 1H-Purine-2,6-dione, 3,9-dihydro-8-[1-(phenylmethyl)-1H-pyrazol-4-yl]-1,3-dipropyl-. CAS No. 531506-36-2. Molecular formula: C21H24N6O2. Mole weight: 392.45. | |
| A2FB N-Glycan | A2FB N-Glycan is an indispensable compound in the biomedical field, playing a significant role in elucidating and deciphering the intricate N-glycosylation profiles discernible in diverse pharmaceuticals and ailments. Synonyms: sialyl, fucosylated, bisected biantennary N-linked glycan. | |
| A2F Glycan, 2-AA labelled | A2F Glycan, 2-AA labelled, a highly specialized chemical utilized in the biomedical industry, possesses immense potential in decoding the intricate processes of glycosylation in the human body, playing a pivotal role in shedding light on several degenerative diseases, including Alzheimer's and Parkinson's. Its effectiveness lies in serving as an indispensable tool in drug development, with its ability to aid in targeting these illnesses. This scientific marvel has indeed revolutionized the study of glycosylation through its unparalleled contributions to medical research and development. | |
| A2F Glycan, 2-AB labelled | | |
| A2F N-Glycan | A2F N-Glycan: A2F N-Glycan is a biomolecule widely found in human cells, involved in glycosylation process. It is commonly used in the biomedicine industry for studying age-related macular degeneration (AMD) as well as other diseases related to glycation, such as Alzheimer's and diabetes. A2F N-Glycan also plays a crucial role in developing therapeutic drugs targeted to these diseases. Synonyms: Disialo, galactosylated, fucosylated, biantennary (A2F); Di-sialylated, galactosylated, core-fucosylated bi-antennary N-linked glycan; FA2G2S2 Glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), bis(sialyl-galactosyl-N-acetylglucosaminyl); (NeuNAc-Gal-GlcNAc)2Man2(Fuc)(GlcNAc)2; A2F glycan. Grades: ≥90%. CAS No. 108341-22-6. Molecular formula: C90H148N6O66. Mole weight: 2370.14. | |
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