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| Product | Description | |
|---|---|---|
| A 779 | A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor) (IC50 = 0.3 nM) with no significant affinity for AT1 or AT2 receptors at a concentration of 1 μM. Synonyms: A-779; A779; (D-Ala7)-Angiotensin I/II (1-7); Asp-Arg-Val-Tyr-Ile-His-D-Ala-OH; 5-L-isoleucine-7-D-alanine-1-7-angiotensin II; 7-Ala-angiotensin (1-7); A 778; A 779; A-778; A779 peptide; angiotensin (1-7), Ala(7)-; angiotensin (1-7), alanyl(7)-; Asp-Arg-Val-Tyr-Ile-His-Ala; aspartyl-arginyl-valyl-tyrosyl-isoleucyl-histidyl-alanine. Grades: 98%. CAS No. 159432-28-7. Molecular formula: C39H60N12O11. Mole weight: 872.97. |  |
| A-7 hydrochloride | A-7 hydrochloride is a cell-permeable antagonist of calmodulin that inhibits calmodulin-activated PDE activity with an IC50 of 3 μM. Calmodulin is a calcium-dependent protein expressed in all eukaryotic cells, modulating the interaction of calcium with target proteins. Synonyms: A-7 monohydrochloride; A 7 hydrochloride; A7 hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide hydrochloride; N-(10-Aminodecyl)-5-chloro-1-naphthalenesulfonamide monoydrochloride. Grades: ≥95%. CAS No. 79127-24-5. Molecular formula: C20H29ClN2O2S.HCl. Mole weight: 433.44. | |
| A-802715 | A802715, a methylxanthine derivative, is an anti-tumor agent with a TD50 (toxic dose of 50%) of 0.9-1.1 mM. Synonyms: 1-(5-hydroxy-5-methylhexyl)-3-methyl-7-propylpurine-2,6-dione; 1-(5-hydroxy-5-methyl)hexyl-3-methyl-7-propylxanthine; A 80 2715; A 802715; A-802715. CAS No. 107767-58-8. Molecular formula: C16H26N4O3. Mole weight: 322.4. | |
| A 804598 | A 804598 is a potent and competitive P2X7 receptor antagonist (IC50 = 8.9, 9.9 and 10.9 nM for mouse, rat and human P2X7 receptors, respectively). Synonyms: A-804598; A 804598; A804598. N-Cyano-N"-[(1S)-1-phenylethyl]-N'-5-quinolinyl-guanidine; 1-cyano-2-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine. Grades: ≥99% by HPLC. CAS No. 1125758-85-1. Molecular formula: C19H17N5. Mole weight: 315.37. | |
| A-80915 A | A-80915 A is a naphthoquinone antibiotic produced by Streptomyces aculeolatus A80915. Activity against gram-positive bacteria. Synonyms: 2H-Naphtho(2,3-b)pyran-5,10-dione, 3,4a-dichloro-10a-((3-chloro-2,2-dimethyl-6-methylenecyclohexyl)methyl)-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2,7-trimethyl-. Grades: >98%. CAS No. 127875-60-9. Molecular formula: C26H31Cl3O5. Mole weight: 529.88. | |
| A-80915 B | A-80915 B is a naphthoquinone antibiotic produced by Streptomyces aculeolatus A80915. Activity against gram-positive bacteria. Synonyms: Antibiotic A 80915B; Napyradiomycin A80915B. CAS No. 127875-61-0. Molecular formula: C26H29Cl3N2O5. Mole weight: 555.88. | |
| A-80915 C | A-80915 C is a naphthoquinone antibiotic produced by Streptomyces aculeolatus A80915. Activity against gram-positive bacteria. Synonyms: 3,4a-dichloro-10a-(3-chloro-6-hydroxy-2,2,6-trimethyl-cyclohexylmethyl)-6,8-dihydroxy-2,2,7-trimethyl-3,4,4a,10a-tetrahydro-2H-benzo[g]chromene-5,10-dione. CAS No. 127875-62-1. Molecular formula: C26H33Cl3O6. Mole weight: 547.89. | |
| A-80915 D | A-80915 D is a naphthoquinone antibiotic produced by Streptomyces aculeolatus A80915. Activity against gram-positive bacteria. Synonyms: Antibiotic A 80915D. CAS No. 127875-63-2. Molecular formula: C26H31Cl3N2O6. Mole weight: 573.89. | |
| A81988 | A81988 is a potent, orally active angiotensin I1 antagonist with a long duration of action whose pharmacological profile has established it as an important tool for the investigation of a variety of A11 mediated pathological conditions. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: 2-[propyl-[[4-[2- (2H-tetrazol-5-yl) phenyl]phenyl]methyl]amino]pyridine-3-carboxylic acid; 2-(N-propyl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)pyridine-3-carboxylic acid; A 81988; A-81988; A81988; Abbott 81988; Abbott-81988. CAS No. 141887-34-5. Molecular formula: C23H22N6O2. Mole weight: 414.46. | |
| A-82548A | A82548A is a macrolide antibiotic containing spiroacetal produced by Streptomyces diastatochromogenes. Synonyms: A82548A. CAS No. 171423-45-3. Molecular formula: C47H81NO14. Mole weight: 884.14. | |
| A-83-01 | A 83-01 is an inhibitor of TGF-β type I receptor kinase (ALK5), activin type IB receptor (ALK4), and nodal type I receptor (ALK7) (IC50s = 12, 45, and 7.5 nM, respectively). It blocks the phosphorylation of SMAD2/3 and inhibits TGF-β-induced epithelial-to-mesenchymal transition. Synonyms: A8301; A 8301; A-8301. Grades: 98%. CAS No. 909910-43-6. Molecular formula: C25H19N5S. Mole weight: 421.52. | |
| A83016A | A83016A is a kinamycin antibiotic produced by an unidentified actinomycete 83016. It has activity against gram-positive bacteria such as Staphylococcus, Streptococcus, Streptococcus pneumoniae and Enterococcus. The MIC is between 0.06-4.0 μg/mL, similar to other members of the Kinamycin group. Synonyms: 1-(Acetyloxy)-5-cyano-3,7-dihydroxy-3-methyl-6,11-dioxo-2,3,4,5,6,11-hexahydro-1H-benzo[b]carbazole-2,4-diyl bis(2-methylpropanoate). Grades: >98%. CAS No. 142383-42-4. Molecular formula: C28H28N2O10. Mole weight: 552.53. | |
| A83016F | A83016F is an Aurodox antibiotic produced by an unidentified actinomycete 83016F. It has weak antibacterial activity. Synonyms: A-83016F; A 83016F. Grades: >98%. CAS No. 142435-72-1. Molecular formula: C37H55NO10. Mole weight: 673.83. | |
| A83586C | A83586C is an ester peptide antibiotic produced by Streptomyces karnatakensis. It has strong anti-Gram-positive bacteria activity, and the MIC of Staphylococcus aureus and Streptococcus is 0.008-0.06 μg/mL. The IC50 for human T-cell leukemia CCRF-CEM cells is 0.0135 μg/mL. Synonyms: Antibiotic A 83586C. Grades: >98%. CAS No. 116364-81-9. Molecular formula: C47H76N8O14. Mole weight: 977.15. | |
| A-92 | A-92 inhibits the stress response of general control nonderepressible 2 kinase (GCN2 or EIF2AK4) (IC50 value of <0.3 μM). It is potentially used as a chemotherapeutic drug for the treatment of cancer. Uses: Potential chemotherapeutic drug. Synonyms: A-92; A 92; A92. Grades: 99%. CAS No. 1448693-69-3. Molecular formula: C19H18N10O. Mole weight: 402.41. | |
| A 967079 | A 967079 is a selective TRPA1 channel blocker (IC50 = 67 and 289 nM at human and rat TRPA1 receptors, respectively) with 1000-fold selectivity for TRPA1 over other TRP channels. A 967079 was shown to have analgesic effects in a rat osteoarthritic pain model. Synonyms: A-967079; A 967079; A967079; (1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-pentene-3-one oxime; 1-(4-Fluorophenyl)-2-methyl-1-penten-3-one oxime. Grades: ≥98% by HPLC. CAS No. 1170613-55-4. Molecular formula: C12H14FNO. Mole weight: 207.24. | |
| AA 147 | AA 147 is an endoplasmic reticulum (ER) proteostasis regulator. Activates the ATF6 transcriptional program independently of ER stress and/or global UPR activation. Selectively reduces secretion of amyloidogenic transthyretin (TTR) from HepG2 cells. Reduces amyloidogenic immunoglobulin light chain (ALLC) secretion from ALMC-2 cells (EC50 = 1.1 μM). Synonyms: N-(2-Hydroxy-5-methylphenyl)benzenepropanamide; N-(2-hydroxy-5-methylphenyl)-3-phenylpropanamide. Grades: ≥98%. CAS No. 393121-74-9. Molecular formula: C16H17NO2. Mole weight: 255.31. | |
| AA-57 | AA-57 is an acidic lipophilic antibiotic produced by Streptomyces sp. AA-57. It has anti-gram-positive bacteria, negative bacteria and mycobacterial activity. Synonyms: AA-57; Pentaleno(1,6a-c)pyran-5-carboxylic acid, 1-(chloromethyl)-1,2,4,4a,6a,7-hexahydro-1-hydroxy-7,8-dimethyl-2-oxo-, (1S-(1alpha,4aalpha,6abeta,7alpha,9aR*))-; Pentaleno(1,3a-c)pyran-5-carboxylic acid, 1,2,4,4a,6a,7-hexadyro-1-(chloromethyl)-7,8-dimethyl-1-hydroxy-2-oxo-. Grades: >98%. CAS No. 68026-87-9. Molecular formula: C15H17ClO5. Mole weight: 312.74. | |
| AACOCF | AACOCF, an anlogue of arachidonic acid, is a slow-binding inhibitor of cytosolic (85 kDa) phospholipase A2. It also inhibits fatty acid amide hydrolase (FAAH, anandamide amidase) in vitro. Synonyms: 1,1,1-Trifluoro-6Z,9Z,12Z,15Z-heneicosateraen-2-one; Arachidonyl trifluoromethyl ketone; Arachidonyltrifluoromethane. CAS No. 149301-79-1. Molecular formula: C21H31F3O. Mole weight: 356.47. | |
| a,a-D-Trehalose dihydrate endotoxin free | Cas No. 6138-23-4. | |
| AA-dUTP | Cas No. 85280-65-5. | |
| AAF-CMK trifluoroacetate salt | AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Synonyms: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grades: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84. | |
| AAI101 | AAI101 is a novel β-lactamase inhibitor with activity against extended-spectrum β-lactamases (ESBL), as well as, some class A and class D carbapenemases. Uses: Beta-lactamase inhibitors. Synonyms: AAI-101; AAI101. CAS No. 1001404-83-6. Molecular formula: C11H14N4O5S. Mole weight: 314.32. | |
| AalDefD | AalDefD is an antimicrobial peptide produced by Aedes albopictus (Yellowfever mosquito). It has antimicrobial activity and has three intramolecular disulfide bonds. Synonyms: Aedes albopictus defensin D; Defensin-D; AaeDefD; Ala-Thr-Cys-Asp-Leu-Leu-Ser-Gly-Phe-Gly-Val-Gly-Asp-Ser-Ala-Cys-Ala-Ala-His-Cys-Ile-Ala-Arg-Gly-Asn-Arg-Gly-Gly-Tyr-Cys-Asn-Ser-Lys-Lys-Val-Cys-Val-Cys-Pro-Ile. Grades: >98%. Molecular formula: C166H264N52O52S6. Mole weight: 4012.65. | |
| A antigen hexaose type 2 | A Antigen Hexaose Type 2 is a antigen hexaose type 2 employed in the research of autoimmune disorders such as rheumatoid arthritand psoriasis. Synonyms: GalNAca-3(fuca-2)Galb-4GlcNAcb-3Galb-4Glc. CAS No. 30461-82-6. Molecular formula: C40H68N2O30. Mole weight: 1056.96. | |
| A antigen pentaose | A antigen pentaose is a vital component in the development of diagnostic tests for infectious diseases. By combining specific sugars and antigens, this compound assists in identifying pathogens responsible for diseases such as influenza and meningitis. Synonyms: GalNAca-3(Fuca-2)Galb-4GlcNAcb-3Gal. CAS No. 1352644-11-1. Molecular formula: C34H58N2O25. Mole weight: 894.82. | |
| Aaptamine | Aaptamine, a spongean alkaloid isolated from a sea sponge Aaptos aaptos, is a competitive antagonist of α-adrenoceptor and activates the p21 promoter in a p53-independent manner. Synonyms: 8,9-dimethoxy-1H-benzo[de][1,6]naphthyridine. Grades: ≥95%. CAS No. 85547-22-4. Molecular formula: C13H12N2O2. Mole weight: 228.3. | |
| AAT-008 | AAT-008 is an orally bioavailable and potent antagonist of the prostaglandin E2 (PGE2) receptor subtype 4 (EP4; IC50 = 16.3 nM in a human EP4 functional assay). Synonyms: 4-[(1S)-1-[[5-chloro-2-(3-fluorophenoxy)pyridine-3-carbonyl]amino]ethyl]benzoic acid. Grades: ≥98%. CAS No. 847727-81-5. Molecular formula: C21H16ClFN2O4. Mole weight: 414.8. | |
| AA-UTP | AA-UTP is a substrate for RNA polymerase with amino group that can be labeled with a fluorescent dye, biotin or other markers. Synonyms: 5- (3- Aminoallyl)uridine- 5'- O- triphosphate. Grades: ≥ 95% by HPLC. CAS No. 85280-66-6. Molecular formula: C12H20N3O14P3 (free acid). Mole weight: 539.2 (free acid). | |
| AB-0022A | AB-0022A is an antibiotic produced by Dictyostelium purpureum K1001. It has anti-Gram-positive bacteria activity, the MIC against Staphylococcus is 0.39-3.13 μg/mL, and the MIC against Streptococcus and Enterococcus is 25-50 μg/mL. Synonyms: AB0022A. Molecular formula: C20H19Cl3O6. Mole weight: 461.72. | |
| AB023 A | AB023 A is a pentaene macrolide antibiotic produced by Streptomyces sp. SD581 and K9925278. It has the activity against several pathogenic fungi such as black koji and Candida albicans. The MIC of Botrytis cinerea is 5 μg/mL. Synonyms: Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,10,12,14,16-hexahydroxy-3,15,27,28-tetramethyl-. CAS No. 141443-39-2. Molecular formula: C31H50O8. Mole weight: 550.72. | |
| AB023 B | AB023 B is a pentaene macrolide antibiotic produced by Streptomyces sp. SD581 and K9925278. It has the activity against several pathogenic fungi such as black koji and Candida albicans. CAS No. 141443-40-5. Molecular formula: C32H52O8. Mole weight: 564.75. | |
| AB05831 | An analogue of deoxynojirimycin, was found to be a potent inhibitor of a number of N-acetylglucosaminidases. Synonyms: 2-Acetamido-1,2-Dideoxynojirmycin; 2-Acetamido-1,2,5-trideoxy-1,5-imino-D-glucitol; 2-Addnj; AdNJ; DNJNAc. Grades: 0.98. CAS No. 105265-96-1. Molecular formula: C8H16N2O4. Mole weight: 204.22. | |
| AB 3217-A | AB3217-A is an anti-mite substance produced by Streptomyces platensis AB2317. Synonyms: Antibiotic AB3217A; AB-3217-A. Grades: >98%. CAS No. 139158-99-9. Molecular formula: C17H23NO7. Mole weight: 353.37. | |
| AB-400 | AB-400 is a tetraene macrolide produced by Streptomyces costae. It has anti-Candida activity with an MIC of 4.6-18.0 μg/mL, which is lower than Nystatin and Amphotrecin B. Molecular formula: C33H48N2O12. Mole weight: 664.74. | |
| AB 5046 A | AB 5046 A is a substance produced by Nodulisporium AB5046 that causes plant chlorosis. It has the activity of inducing chlorosis of monocotyledonous and dicotyledonous plants. Synonyms: 2-Cyclohexen-1-one, 3,5-dihydroxy-2-(1-oxobutyl)-, (+/-)-; (+/-)-3,5-Dihydroxy-2-(1-oxobutyl)-2-cyclohexen-1-one. Grades: >98%. CAS No. 154037-62-4. Molecular formula: C10H14O4. Mole weight: 198.22. | |
| AB 5046 B | AB 5046 B is a substance produced by Nodulisporium AB5046 that causes plant chlorosis. It has the activity of inducing chlorosis of monocotyledonous and dicotyledonous plants. Synonyms: 2-Cyclohexen-1-one, 2-acetyl-3,5-dihydroxy-, (+/-)-. Grades: >98%. CAS No. 154037-63-5. Molecular formula: C8H10O4. Mole weight: 170.16. | |
| AB928 | AB928 is a dual antagonist of the A2aR and A2bR adenosine receptors with Kb of 1.5 and 2.0 nM, respectively. It potently blocks the immunosuppressive effects of high adenosine concentrations in the tumor microenvironment. Synonyms: A2Ar/A2bR antagonist-1; 3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile. CAS No. 2239273-34-6. Molecular formula: C23H22N8O. Mole weight: 426.5. | |
| Abacavir | Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Synonyms: Ziagen. Grades: >98%. CAS No. 136470-78-5. Molecular formula: C14H18N6O. Mole weight: 286.33. | |
| Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester | Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Molecular formula: C33H46N6O10. Mole weight: 686.75. | |
| Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine | Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir USP Related Compound D; Abacavir EP Impurity B; Abacavir Impurities; Abacavir EP Impurity B. CAS No. 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88. | |
| Abacavir 5'-β-D-Glucuronide | Abacavir 5'-β-D-Glucuronide is a metabolite of Abacavir. Synonyms: [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl]methyl-?-D-Glucopyranosiduronic Acid; Abacavir 5'-Glucuronide. Grades: > 95%. CAS No. 384329-76-4. Molecular formula: C20H26N6O7. Mole weight: 462.46. | |
| Abacavir 5-Phosphate | Cas No. 136470-77-4. | |
| Abacavir Carboxylate | A major metabolite of Abacavir in human urine and cerebrospinal fluid. Synonyms: (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-carboxylic Acid. Grades: > 95%. CAS No. 384380-52-3. Molecular formula: C14H16N6O2. Mole weight: 300.32. | |
| Abacavir-[d4] | Abacavir-[d4] is the labelled analogue of Abacavir, which is a nucleoside reverse transcriptase inhibitor. Synonyms: Abacavir-d4; (1S,4R)-4-[2-Amino-6-(cyclopropylamino-d4)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1S-cis)-4-[2-Amino-6-(cyclopropylamino-d4)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ABC-d4; Ziagen-d4. Grades: 97%; ≥95% atom D. CAS No. 1260619-56-4. Molecular formula: C14H14D4N6O. Mole weight: 290.36. | |
| Abacavir Impurity 1 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Synonyms: 2-Cyclopentene-1-methanol, 4-(2-amino-6-chloro-7H-purin-7-yl)?-, (1S-cis)?- (9CI). Grades: > 95%. CAS No. 178327-20-3. Molecular formula: C11H14ClN5O. Mole weight: 267.72. | |
| Abacavir Impurity 2 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Synonyms: (1S,4R)-4-<(2',5'-diamino-6'-chloropyrimidin-4'-yl)amino>cyclopent-2-enylmethanol. Grades: > 95%. CAS No. 122624-77-5. Molecular formula: C10H14ClN5O. Mole weight: 255.71. | |
| Abacavir impurity 3 | A metabolite of Abacavir in human urine and cerebrospinal fluid. Synonyms: Abacavir impurity G; t-Butyl derivative abacavir; 9-((1R,4S)-4-(tert-Butoxymethyl)cyclopent-2-enyl)-N6-cyclopropyl-9H-purine-2,6-diamine. Grades: > 95%. CAS No. 1443421-68-8. Molecular formula: C18H26N6O. Mole weight: 342.45. | |
| Abacavir sulfate | Abacavir is an antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC50 value of 5.3 μM. Synonyms: 2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-, sulfate (2:1). Grades: ≥98%. CAS No. 216699-07-9. Molecular formula: C14H18N6O·H2SO4. Mole weight: 384.4. | |
| Abacavir Sulfate (2:1) | Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1. Abacavir is an analog of guanosine (a purine). Its target is the viral reverse transcriptase enzyme. Synonyms: 1592U89. Grades: 95%. CAS No. 188062-50-2. Molecular formula: C14H18N6O.1/2H2O4S. Mole weight: 335.35. | |
| Abaecin | Abaecin is an antimicrobial peptide produced by Apis mellifera (Honeybee). It has antibacterial activity. Synonyms: Tyr-Val-Pro-Leu-Pro-Asn-Val-Pro-Gln-Pro-Gly-Arg-Arg-Pro-Phe-Pro-Thr-Phe-Pro-Gly-Gln-Gly-Pro-Phe-Asn-Pro-Lys-Ile-Lys-Trp-Pro-Gln-Gly-Tyr-OH. Grades: >97%. CAS No. 123997-18-2. Molecular formula: C187H270N48O43. Mole weight: 3878.50. | |
| Abaecin 1 precursor | Abaecin 1 precursor is an antimicrobial peptide produced by Solenopsis invicta (Red imported fire ant). It has antimicrobial activity. Synonyms: Gln-Pro-Pro-Ile-Arg-Asn-Pro-Pro-Pro-Gly-Gly-Trp-Lys-Pro-Phe-Pro-Thr-Phe-Pro-Gly-Gln-Gly-Pro-Tyr-Asn-Pro-Lys-Ile-Arg-Phe-Pro-His. Grades: ≥96%. | |
| Abaecin isoform 1 | Abaecin isoform 1 is an antimicrobial peptide produced by Bombus terrestris (Buff-tailed bumblebee). It has antimicrobial activity. Synonyms: Val-Pro-Tyr-Asn-Pro-Pro-Arg-Pro-Gly-Gln-Ser-Lys-Pro-Phe-Pro-Thr-Phe-Pro-Gly-His-Gly-Pro-Phe-Asn-Pro-Lys-Thr-Gln-Trp-Pro-Tyr-Pro-Leu-Pro-Asn-Pro-Gly-His. Grades: 96%. | |
| Abaecin isoform 2 | Abaecin isoform 2 is an antimicrobial peptide produced by Bombus terrestris (Buff-tailed bumblebee). It has antimicrobial activity. Synonyms: Pro-Pro-Arg-Pro-Gly-Gln-Ser-Lys-Pro-Phe-Pro-Thr-Phe-Pro-Gly-His-Gly-Pro-Phe-Asn-Pro-Lys-Thr-Gln-Trp-Pro-Tyr-Pro-Leu-Pro-Asn-Pro-Gly-His. Grades: ≥97%. | |
| Abaecin-like | Abaecin-like is an antimicrobial peptide produced by Bombus impatiens (Bumblebee). It has antimicrobial activity. Synonyms: Pro-Pro-Arg-Pro-Gly-Gln-Ser-Lys-Pro-Phe-Pro-Ser-Phe-Pro-Gly-His-Gly-Pro-Phe-Asn-Pro-Lys-Ile-Gln-Trp-Pro-Tyr-Pro-Leu-Pro-Asn-Pro-Gly-His. Grades: ≥95%. | |
| abafungin | Abafungin is a broad-spectrum antifungal agent with a novel mechanism of action originated by York Pharma. In Aug 2009, Phase-III for Dermatomycoses in Japan and Europe was discontinued. At the same time, preclinical for Onychomycosis in United Kingdom was discontinued. Uses: Dermatomycoses; onychomycosis. Synonyms: N-[4-[2-(2,4-dimethylphenoxy)phenyl]-1,3-thiazol-2-yl]-1,4,5,6-tetrahydropyrimidin-2-amine;Abafungin;BAY-W 6341;N-[4-[2-(2,4-Dimethylphenoxy)phenyl]-2-thiazolyl]-1,4,5,6-tetrahydro-2-pyrimidinamine. Grades: 95%. CAS No. 129639-79-8. Molecular formula: C21H22N4OS. Mole weight: 378.50. | |
| Abaloparatide | Abaloparatide is an analogue of parathyroid hormone-related protein (PTHrP) which is used for the treatment of osteoporosis. In 28 April 2017, it was approved by FDA for the treatment of postmenopausal women with osteoporosis. Studies showed that abaloparatide could decrease the risk of new vertebral and nonvertebral fractures. Uses: The treatment of osteoporosis. Synonyms: Tymlos. Grades: 98%. CAS No. 247062-33-5. Molecular formula: C174H300N56O49. Mole weight: 3960.58. | |
| Abamectin | Avermectin B1 (Abamectin) is a widely used insecticide and anthelmintic. It is a mixture of avermectins containing more than 80% avermectin B1a and less than 20% avermectin B1b, which have very similar biological and toxicological properties. Avermectin B1 is a natural fermentation product of this bacterium. Synonyms: Avomec; Agri-Mek; Avid; Agrimek; Vertimec; Affirm; Zephyr; MK 936; MK 0936; NSC 758202; Avermectin B1; MK-936; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran], avermectin B1 deriv.; A 14906; A 8612; Abamektin; Abamitel; Abarex; Abastate; Abastate EW; Abathor; Abba; Agador; AgMectin; Agri-Mek; Agri-Mek SC; Agrimec; Avermectin B1a-Avermectin B1b mixt.; Aversectin S; Avert; Avicta; Avicta 400FS; Avid 0.15EC; CHA 2061; CHA 2062; Dalamectin; Dalamektin; Epi-Mek; Fitoverm; Fitoverm M; Genesis Oral Drench; Genesis Pour-on for Cattle and Deer; Kraft; KRAFT 36 EC; L 676; Lirosect; Lyrosekt; Mectin; Phytoverm; PT 310; Rustomectin; STAN; Temprano; Vermitec; Vertigo (pesticide); Vertigo 018EC; Vertimec 018SC; Zoro. Grades: >95% a mixture of B1a and B1b. CAS No. 71751-41-2. Molecular formula: C48H72O14.C47H70O14. Mole weight: 1732.14. | |
| Abametapir-[d6] | Abametapir-[d6] is an isotopic labelled of Abametapir. Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases, enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. CAS No. 1803416-92-3. Molecular formula: C12H6D6N2. Mole weight: 190.27. | |
| Abanoquil mesilate | This molecular is an active biochemical as a Alpha 1 adrenergic receptor antagonist. However, no developments were reported for Ischaemic heart disorders and Arrhythmias. Uses: Arrhythmias; ischaemic heart disorders. Synonyms: 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine;methanesulfonic acid,TCMDC-131968, TCMDC 131968, TCMDC131968, UK 52046; UK-52046; UK52046; Abanoquil. Grades: 98%. CAS No. 118931-00-3. Molecular formula: C23H29N3O7S. Mole weight: 491.56. | |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grades: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
| Abasic II Phosphoramidite | Abasic II Phosphoramidite, a highly valuable chemical compound, plays a pivotal role in oligonucleotide synthesis, particularly in the context of medicinal applications, as it affords the unique ability to generate modified nucleic acids that combat cancer and genetic disorders. This innovative compound is exceedingly crucial in the biomedical sphere as it transforms the course of advanced therapeutics. Synonyms: 5-O-Dimethoxytrityl-1-O-tert-butyldimethylsilyl-2-deoxyribose-3-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Molecular formula: C41H59N2O7PSi. Mole weight: 750.98. | |
| Abbeymycin | Abbeymycin is an antibiotic isolated from the Streptomyces sp. AB-999F52. Abbeymycin has weak antibacterial activity against several anaerobic bacteria (such as Bacteroides fragilis, Bacteroides polymorpha, Peptococcus and Peptostreptococcus, etc.). Synonyms: (2S,11S,11aS)-2-Hydroxy-11-methoxy-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; (2S)-2α-Hydroxy-11β-methoxy-1,2,3,10,11,11aβ-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2-hydroxy-11-methoxy-, (2S,11S,11aS)-; 5H-Pyrrolo(2,1-c)(1,4)benzodiazepin-5-one, 1,2,3,10,11,11a-hexahydro-2-hydroxy-11-methoxy-, (2S-(2-α,11-β,11a-β))-. Grades: 95%. CAS No. 108073-64-9. Molecular formula: C13H16N2O3. Mole weight: 248.28. | |
| ABBV-744 | ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2, BRD3 and BRD4. It is developed for treating AML and cancers. Synonyms: N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridine-2-carboxamide. Grades: ≥98%. CAS No. 2138861-99-9. Molecular formula: C28H30FN3O4. Mole weight: 491.55. | |
| ABC294640 | ABC294640 is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. Synonyms: ABC-294640; ABC294640; ABC 294640; Opaganib; 3-(4-chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide. Grades: 0.98. CAS No. 915385-81-8. Molecular formula: C23H25ClN2O. Mole weight: 380.9104. | |
| ABC34 | ABC34 is an inactive control probe for JJH260 , the inhibitor of androgen-induced gene 1 (AIG1), an enzyme that hydrolyzes fatty acid esters of hydroxy fatty acids (FAHFAs). Synonyms: 1,3-dioxo-7-(4-phenoxybenzyl)hexahydroimidazo[1,5-a]pyrazin-2(3H)-yl 4-(4-methoxyphenyl)piperazine-1-carboxylate. Grades: ≥98%. CAS No. 1831135-56-8. Molecular formula: C31H33N5O6. Mole weight: 571.6. | |
| ABC99 | ABC99 is an N-hydroxyhydantoin (NHH) carbamate that inhibits the Wnt-deacylating enzyme NOTUM (IC50 = 13 nM). It preserves Wnt3A signaling in the presence of NOTUM (EC50 = 89 nM in a cell-based reporter assay). Grades: ≥95%. CAS No. 2331255-53-7. Molecular formula: C22H21ClN4O5. Mole weight: 456.9. | |
| Abecarnil | Abecarnil was originally developed as an anti-anxiety drug, but has not as yet been commercially developed for use in humans, instead so far mainly being used for research into the development of other new sedative and anxiolytic drugs. Synonyms: propan-2-yl4-(methoxymethyl)-6-(phenylmethoxy)-9H-pyrido[5,4-b]indole-3-carboxylate. Grades: > 95%. CAS No. 111841-85-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. | |
| Abemaciclib | Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: LY-2835219; LY 2835219; LY2835219; Verzenio; N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine. Grades: ≥98%. CAS No. 1231929-97-7. Molecular formula: C27H32F2N8. Mole weight: 506.61. | |
| Abemaciclib-[d5] | Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d5; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d5. Grades: > 98%. CAS No. 1809251-51-1. Molecular formula: C27H27D5F2N8. Mole weight: 511.62. | |
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