MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Trofinetide | Trofinetide (NNZ-2566), a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), has been shown to be neuroprotective in animal models of brain injury. Uses: Scientific research. Group: Peptides. Alternative Names: NNZ-2566. CAS No. 853400-76-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16757. |  |
| Trofosfamide | Trofosfamide is an orally bioavailable oxazaphosphorine derivative with antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 22089-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-119824. | |
| Troglitazone | Troglitazone is an orally active PPARγ agonist, with EC 50 s of 550 nM and 780 nM for human and murine?PPARγ receptor, respectively. Troglitazone has anticancer activity, prevents and inhibits the development of type 2 diabetes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CS-045. CAS No. 97322-87-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-50935. | |
| Troleandomycin | Troleandomycin (Triacetyloleandomycin), a macrolide acrolide antibiotic, is a selective CYP3A inhibitor. Troleandomycin is an oral corticosteroid for asthma study[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Triacetyloleandomycin. CAS No. 2751-9-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-108881. | |
| Trolox | Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53188-07-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-101445. | |
| Tromantadine hydrochloride | Tromantadine hydrochloride, an Amantadine derivative with antiherpetic activity, inhibits herpes simplex virus type 1 (HSV-1) and HSV-2 replication [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 41544-24-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-U00124B. | |
| Trontinemab | Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 ( TFR1 ). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human TFR1 [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: RG6102; RO-7126209. CAS No. 2568868-35-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9999. | |
| Tropic acid | Tropic acid (DL-Tropic acid) is a laboratory reagent used in the chemical synthesis of Atropine and Hyoscyamine [1]. Uses: Scientific research. Group: Natural products. Alternative Names: DL-Tropic acid. CAS No. 552-63-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-W041194. | |
| Tropicamide | Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. When used as an eye drop, Tropicamide causes short-term mydriasis (pupil dilation) and cycloplegia. Tropicamide can be used in the research of neurological diseases, such as epilepsy [1] [2] [3] [4]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Ro 1-7683. CAS No. 1508-75-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0321. | |
| Tropicamide-d3 | Tropicamide-d 3 is the deuterium labeled Tropicamide[1]. Tropicamide (Ro 1-7683) is a selective M4 muscarinic acetylcholine receptor antagonist. Tropicamide produces short acting mydriasis (dilation of the pupil) and cycloplegia when applied as eye drops[2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Ro 1-7683-d3. CAS No. 2673270-13-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0321S. | |
| Tropifexor | Tropifexor (LJN452) is a highly potent agonist of FXR with an EC 50 of 0.2 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LJN452. CAS No. 1383816-29-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-107418. | |
| Tropine | Tropine is a secondary metabolite of Solanaceae plants, is an anticholinergic agent [1]. Tropine is a common intermediate in the synthesis of a variety of bioactive alkaloids, including hyoscyamine and scopolamine [2]. Uses: Scientific research. Group: Natural products. CAS No. 120-29-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-N7061. | |
| Tropinone | Tropinone, an alkaloid, acts as a synthetic intermediate to Atropine [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 532-24-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-Y0135. | |
| Tropisetron | Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT 3 R antagonists with a K i of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor ( α7 nAChR ) with an EC 50 of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ICS-930 free base. CAS No. 89565-68-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0072. | |
| Tropisetron Hydrochloride | Tropisetron Hydrochloride (SDZ-ICS-930) is an effective neuroprotective agent that acts as a 5-HT3 receptor antagonist, a calmodulin inhibitor, and an α7-nAChR receptor agonist, with an IC 50 of 70.1 nM for the 5-HT3 receptor. Tropisetron Hydrochloride has anti-inflammatory properties and immune-regulating functions, effectively alleviating symptoms associated with chemotherapy and post-surgery. Tropisetron Hydrochloride reduces Ab (HY-P4867)-induced hippocampal neuroinflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SDZ-ICS-930. CAS No. 105826-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0020. | |
| Tropolone | Tropolone is a seven-membered non-benzenoid aromatic compound, which is the precursor of many Azulene derivatives. Tropolone is a potent mushroom tyrosinase inhibitor with an IC 50 value of 0.4 μM. Its inhibitory effect can be achieved by dialysis or excess CU 2+ Reversa. Tropolone exhibits broad anti-viral and anti-fungal activity and is synergistic upon co-treatment with nucleos(t)ide analog drugs. Tropolone is a promising candidate for research in osteosarcoma [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 533-75-5. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-N7135. | |
| Tropone | Tropone is a building block in the chemical synthesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Cycloheptatrienone. CAS No. 539-80-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W035904. | |
| Troriluzole | Troriluzole, a third-generation, tripeptide proagent of Riluzole (HY-B0211), is an orally active glutamate modulator. Troriluzole reduces synaptic glutamate level and increases the synaptic glutamate absorption. Troriluzole has the potential for Alzheimer disease and generalized anxiety disorder (GAD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BHV-4157. CAS No. 1926203-09-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122487. | |
| Trospium chloride | Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs) , with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 10405-02-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0461. | |
| Trotabresib | CC-90010 (compound 1) is a reversible and orally active BET inhibitor. CC-90010 is applied in the study for advanced solid tumors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC-90010. CAS No. 1706738-98-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-137573. | |
| Trovafloxacin | Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive , Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC 50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147059-72-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0170. | |
| Trovafloxacin mesylate | Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive , Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC 50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147059-75-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103399. | |
| Troxerutin | Troxerutin, also known as vitamin P4, is a tri-hydroxyethylated derivative of natural bioflavonoid rutins which can inhibit the production of reactive oxygen species ( ROS ) and depress ER stress-mediated NOD activation. Uses: Scientific research. Group: Natural products. Alternative Names: Trihydroxyethylrutin. CAS No. 7085-55-4. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-N0139. | |
| Troxipide | Troxipide is an orally active defensive factor-enhancing therapeutic agent for gastritis and gastric ulcer (GU). Troxipide is a non-antisecretory gastro protective agent with antiulcer, anti-inflammatory and mucus-secreting properties [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 30751-05-4. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0758. | |
| TRPA1-IN-2 | TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC 50 value of 0.04 μM. TRPA1-IN-2 shows anti-inflammation activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2415206-22-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153711. | |
| TRPC6-IN-3 | TRPC6-IN-3 (compound 17) is a potent, orally active transient receptor potential C6 ion channel (TRPC6) inhibitor. TRPC6-IN-3 modulates not only intracellular calcium concentration, but also membrane potential by modulating the flux of cations including calcium and sodium ions. TRPC6-IN-3 can be used in research of respiratory system [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2311863-36-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148129. | |
| TRPM4-IN-2 | TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 ?M. TRPM4-IN-2 can be used for researching prostate cancer and colorectal cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBA. CAS No. 667411-04-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128172. | |
| TRPV2-selective blocker 1 | TRPV2-selective blocker 1 (compound IV2-1) is a selective TRPV2 channel blocker with an IC50?of?6.3??M. TRPV2-selective blocker 1 does not affect TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 also inhibits TRPV2-mediated Ca2+ influx in macrophages, and inhibits macrophage phagocytosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2242724-49-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157131. | |
| True Blue | True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: NCI 240899. CAS No. 71431-30-6. Pack Sizes: 1 mg. Product ID: HY-D1161. | |
| TRULI | TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lats-IN-1. CAS No. 1424635-83-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138489. | |
| TRV055 | TRV055 (TRV120055) is a G protein-biased agonist of angiotensin II type 1 receptors (AT1Rs). TRV120055 induces fibroblast proliferation, overexpression of collagen I and ?-SMA, and stress fibre formation in human cardiac fibroblasts. TRV055 activates AT1 receptor/G?q-mediated signaling pathways, upregulates TGF-?1 and p-ERK1/2. TRV055 induces collagen secretion in adult rat myofibroblasts at a level comparable to Ang II. TRV055 can be used to study the role of G protein-biased signaling of AT1Rs in regulating fibrotic responses[1] | |
| TRV-120027 | TRV120027, a β-arrestin-1 -biased agonist of the angiotensin II receptor type 1 (AT1R) , engages -arrestins while blocking G-protein signaling [1]. TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R - β-arrestin-1 - TRPC3 - PLCγ at the plasma membrane. TRV120027 inhibits angiotensin II - mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment [2]. Uses: Scientific research. Group: Peptides. CAS No. 1234510-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2141. | |
| Trypsin | Trypsin is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin activates PAR2 and PAR4. Trypsin induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin also promotes cell proliferation and differentiation. Trypsin can be used in the research of wound healing and neurogenic inflammation [1] [2] [3] [4] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-7-7. Pack Sizes: 100 mg; 500 mg; 1 g. Product ID: HY-129047. | |
| Trypsin Inhibitor, soybean | Trypsin Inhibitor, soybean is a potent and reversible inhibitor of trypsin [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9035-81-8. Pack Sizes: 50 mg; 100 mg. Product ID: HY-126388. | |
| Trypsin (MS grade) | Trypsin MS grade is a serine protease enzyme, and hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin MS grade activates PAR2 and PAR4. Trypsin MS grade induces cell-to-cell membrane fusion in PDCoV infection by the interaction of S glycoprotein of PDCoV and pAPN. Trypsin MS grade also promotes cell proliferation and differentiation. Trypsin MS grade can be used in the research of wound healing and neurogenic inflammation [1] [2] [3] [4] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-7-7. Pack Sizes: 100 μg. Product ID: HY-129047A. | |
| Tryptamine | Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist (EC50=1-3 mM) and an endogenous ligand of the aryl hydrocarbon receptor (AHR) (Kd=10-50 nM). Tryptamine promotes intestinal anion secretion and fluid transport by activating G protein-coupled receptors (GPCRs) and accelerates gastrointestinal motility. Tryptamine regulates Th17/Treg balance to inhibit neuroinflammation, competitively binds to 5-HT receptors to regulate central nervous system activity, and participates in temperature regulation and spinal reflex regulation as a neuromodulator. Tryptamine can be used to study intestinal motility disorders such as functional constipation, and has shown significant efficacy in multiple sclerosis models [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-(2-Aminoethyl)indole~2-(3-Indolyl)ethylamine. CAS No. 61-54-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B2132. | |
| Tryptamine hydrochloride | Tryptamine hydrochloride belongs to the class of indole alkaloids and is a derivative of the amino acid tryptophan. Tryptamine hydrochloride is psychoactive and acts as a neurotransmitter in the body, affecting mood, perception and cognition. In its hydrochloride form, Tryptamine hydrochloride hydrochloride, it is commonly used as a research chemical and as a starting material for the synthesis of other organic compounds. It can also occur naturally in certain plants and animals, including fungi and mammals. Due to the psychoactive properties of Tryptamine hydrochloride and its derivatives, its use and possession are controlled substances in many countries. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 343-94-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W014971. | |
| Tryptanthrin | Tryptanthrin is an indole quinazoline that could be an alkaloid from indigo-bearing plants. Tryptanthrin is a potent and orally active cellular Leukotriene (LT) biosynthesis inhibitor. Tryptanthrin has anticancer activity. Tryptanthrin suppresses the expression levels of NOS1, COX-2, and NF-κB and regulates the expression levels of IL-2, IL-10, and TNF-α [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 13220-57-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N6607. | |
| Tryptone | Tryptone is a common component of biological media. Tryptone is the polypeptone derived from the protein hydrolysis of animal tissue (pancreas) and digested by pancreatic enzymes. The main components of Tryptone were the digestion of casein by trypsin, including the peptones, small peptides and amino acids generated from the hydrolysis of casein. Tryptone provides nutrients needed for bacterial growth, especially nitrogen and carbon sources. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 73049-73-7. Pack Sizes: 25 g; 50 g. Product ID: HY-W133898. | |
| Tryptophol | Tryptophol (Indole-3-ethanol) is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: Indole-3-ethanol. CAS No. 526-55-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W010155. | |
| TS-021 free base | DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) , a highly specific serine protease , with an IC 50 of 4.6 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DPP-IV-IN-1. CAS No. 625110-37-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-U00346. | |
| TS-24 | TS-24 is an inhibitor for cathepsin S , with an IC 50 of 4.3 μM. TS-24 exhibits radiosensitizing activity in wild type breast cancer susceptibility gene 1 (BRCA1) and in TNBC xenograft mice model, through induction of apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1563260-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162477. | |
| TsDPEN | TsDPEN (Compound 2) is a biochemical reagent. TsDPEN derivatives containing N,N,N imide chiral ligands can be applied to copper catalyzed asymmetric Kinugasa reactions [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 144222-34-4. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W002878. | |
| TSPC | TSPC is a phytohormone gibberellin (GA) perception inhibitor with an IC 50 value of 10 μM in vitro [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 882286-32-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-125979. | |
| TSPP tetrasodium | TSPP tetrasodium is a photosensitizer that has shown impressive effects in in vivo regression of cancer and microorganism infections (Ex: 413 nm, Em: 640 nm) [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 39050-26-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-W035051. | |
| TSQ | TSQ is a cytosolic zinc ion fluorescence probe that is membrane permeable and can be used for intracellular imaging of zinc proteins (λ max ~470 nm). TSQ can combine with Zn 2+ in the presence of Ca 2+ and Mg 2+ to produce blue fluorescence [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 109628-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119287. | |
| TSTU | TSTU is able to converse carboxylic acid to the corresponding N-hydroxysuccinimidyl (NHS) ester, and is utilized as coupling reagent in peptide chemistry [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 105832-38-0. Pack Sizes: 25 g. Product ID: HY-W011412. | |
| TT-012 | TT-012 specifically binds to dynamic MITF and destroys the latter's dimer formation and DNA-binding ability. TT-012 inhibits the transcriptional activity of MITF in B16F10 melanoma cells. TT-012 inhibits the growth of high-MITF melanoma cells, and inhibits the tumor growth and metastasis with tolerable toxicity to liver and immune cells in animal models[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1164471-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156483. | |
| TT-10 | TT-10 (TAZ-K) is an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAZ-K. CAS No. 2230640-94-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125016. | |
| TT-232 | TT-232 (CAP-232), a somatostatin derivative, is a peptide SSTR1/SSTR4 agonist. TT-232 inhibits cancer cell proliferation and induces apoptosis. TT-232 is also a broad-spectrum anti-inflammatory and analgesic agent[1][2][4]. Uses: Scientific research. Group: Peptides. Alternative Names: CAP-232; TLN-232. CAS No. 147159-51-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-105172. | |
| TT3 | TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1821214-50-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148049. | |
| TTA-A2 | TTA-A2 is a potent, selective and orally active t-type voltage gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 953778-63-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111828. | |
| TTA-P2 | TTA-P2 (T-Type calcium channel inhibitor) is a potent inhibitor of T-Type calcium channel. TTA-P2 penetrates well the CNS and blocks the native T-type currents in deep cerebellar nuclear neurons, the window current is completely abolished both for wild-type and mutant Cav3.1 channels. TTA-P2 has the potential for the research of neurology disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-Type calcium channel inhibitor. CAS No. 1072018-68-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-10035. | |
| TTBK1-IN-1 | TTBK1-IN-1 is a potent, selective and brain-penetrant tau tubulin kinase 1 (TTBK1) inhibitor with an IC50 of 2.7 nM. TTBK1-IN-1 can be used for the research of alzheimers disease and related tauopathies[1]. TTBK1-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 2735015-60-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134968. | |
| TTNPB | TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC 50 s of α =5.1 nM, β = 4.5 nM, and γ =9.3 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 13-7410; Arotinoid acid; AGN191183. CAS No. 71441-28-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15682. | |
| TT-OAD2 | TT-OAD2 is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC 50 of 5 nM. TT-OAD2 has the potential for diabetes treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2382719-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-129658A. | |
| TTX-030 | TTX-030 is a humanized antibody expressed in CHO cells, targeting ENTPD1/CD39. TTX-030 contains huIgG4SP heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for TTX-030 can refer to Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Eltivutabart. CAS No. 2935496-38-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990670. | |
| Tubacin | Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1. Tubacin also inhibits metallo-?-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Group: Signaling pathways. CAS No. 537049-40-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13428. | |
| Tubastatin A | Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-?-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Group: Signaling pathways. CAS No. 1252003-15-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13271A. | |
| Tubastatin A Hydrochloride | Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-?-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tubastatin A HCl; TSA HCl. CAS No. 1310693-92-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13271. | |
| Tubeimoside I | Tubeimoside I(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM. Uses: Scientific research. Group: Natural products. Alternative Names: Tubeimoside-1; Lobatoside-H. CAS No. 102040-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0890. | |
| Tubercidin | Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 ?M[1]. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis[2]. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP[1]. Tubercidin has antiviral activity[2]. Uses: Scientific research. Group: Natural products. Alternative Names: 7-Deazaadenosine. CAS No. 69-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100126. | |
| Tuberculosis inhibitor 12 | Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 793729-44-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-49071. | |
| Tuberculosis inhibitor 3 | Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 μg/mL) against agent-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2219325-28-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114147. | |
| Tubulysin | The Tubulysin family of secondary metabolites was originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizers and anti-microtubule toxins ( anti-microtubule toxins ), with effective IC 50 concentrations against multidrug-resistant cancer cell lines. In the picomole range. Tubulysins are ideal candidates for incorporation into small active molecule conjugate (SMDC) delivery systems and are commonly used in ADC synthesis as ADC cytotoxins ( ADC Cytotoxin ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1943604-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-128914. | |
| Tucaresol | Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti- HIV effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BWA589C. CAS No. 84290-27-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106755. | |
| Tucatinib | Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC 50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Irbinitinib; ARRY-380; ONT-380. CAS No. 937263-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16069. | |
| Tucidinostat | Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I ( HDAC1/2/3 ) and class IIb ( HDAC10 ) inhibitor, with IC 50 s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 ( IC 50 s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Chidamide; HBI-8000; CS 055. CAS No. 1616493-44-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109015. | |
| Tuftsin | Tuftsin is a tetrapeptide. Tuftsin is a macrophage/microglial activator. Uses: Scientific research. Group: Peptides. CAS No. 9063-57-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0240. | |
| TUG-891 | TUG-891 is a potent and selective agonist for the long chain free fatty acid (LCFA) receptor 4 ( FFA4/GPR120 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374516-07-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100881. | |
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