MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| UNC5293 | UNC5293 is a MERTK-selective and potent inhibitor (Ki=190 pM). UNC5293 inhibits MERTK (IC50=0.9 nM) and is more selective over Axl, Tyro3 and Flt3. UNC5293 exhibits excellent mouse PK properties and is used for bone marrow leukemia research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226789-82-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132200. |  |
| UNC569 | UNC569 is a potent, reversible, ATP-competitive and orally active Mer kinase inhibitor with an IC50 of 2.9 nM and a Ki of 4.3 nM. UNC569 also inhibits Axl and Tyro3 with IC50s of 37 nM and 48 nM, respectively. UNC569 can be used for acute lymphoblastic leukemia (ALL) and atypical teratoid/rhabdoid tumors research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1350547-65-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-117596. | |
| UNC6852 | UNC6852 is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC and contains an EED (embryonic ectoderm development) ligand and a von Hippel-Lindau ligand, with an IC50 of 247 nM for EED[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2688842-08-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130708. | |
| UNC6934 | UNC6934, a chemical probe targeting the PWWP domain, alters NSD2 nucleolar localization. Uses: Scientific research. Group: Signaling pathways. CAS No. 2561494-77-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145103. | |
| UNC7467 | UNC7467 is a potent IP6K inhibitor with values of 4.9, 8.9 and 1320 nM for IP6K2, IP6K1 and IP6K6, respectively. UNC7467 reduces levels of inositol pyrophosphates. UNC7467 can be used for obesity research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922283-43-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150607. | |
| UNC8153 TFA | UNC8153 TFA is a potent and selective nuclear receptor-binding SET domain-containing 2 (NSD2) -targeted degrader with a K d of 24 nM. UNC8153 TFA reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. UNC8153 TFA contains a simple warhead that confers proteasome-dependent degradation of NSD2 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2929304-61-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-157251. | |
| UNC9512 | UNC9512 is a potent methyl-lysine reader p53 binding protein 1 (53BP1) antagonist. UNC9512 can be used to study the role of 53BP1 in DNA repair, gene editing and tumorigenesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3032393-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-156257. | |
| UNC-CA2-103 | UNC-CA2-103 (compound 128) is a potent inhibitor of Tousled like kinase 2 (TLK2), with the IC50 of 18 nM[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162426. | |
| Undecane | Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α [. Uses: Scientific research. Group: Natural products. CAS No. 1120-21-4. Pack Sizes: 10 mM * 1 mL; 10 g; 25 g. Product ID: HY-N8593. | |
| Undecanedioic acid | Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin. Uses: Scientific research. Group: Natural products. CAS No. 1852-04-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g. Product ID: HY-W014125. | |
| Undecanoic acid | Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Undecanoate; Hendecanoic acid. CAS No. 112-37-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-W004282. | |
| Undecylenate sodium | Undecylenate SodiumIt is an organic compound belonging to the class of carboxylates. It is formed by the reaction of undecylenic acid and sodium hydroxide. Undecylenate SodiumIt has a variety of applications in the cosmetic and personal care industries, especially as an antifungal agent in products such as face creams, lotions and shampoos. In addition, it can be used as a preservative in various formulations. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 3398-33-2. Pack Sizes: 5 g; 10 g; 25 g. Product ID: HY-W127452. | |
| Unesbulin | Unesbulin (PTC596) is an orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 ( BMI-1 ) inhibitor. Unesbulin downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia (AML) cells. Unesbulin has anti-leukemic activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC596. CAS No. 1610964-64-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112041. | |
| Uniconazole | Uniconazole, a plant growth retardant, is a potent inhibitor of abscisic acid (ABA) catabolism with an IC 50 of 68 nM against ABA 8-hydroxylase. Uniconazole is a potent competitive inhibitor of CYP707A3 activity with a K i of 8 nM. Uniconazole evidently inhibits gibberellin biosynthesis, and brassinosteroid biosynthesis is also inhibited to some extent [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 83657-22-1. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0873. | |
| UniPR1331 | UniPR1331 is a 3β-hydroxy-Δ5-choline acid derivative that inhibits Eph-ephrin interactions. UniPR1331 interacts with VEGFR2 and blocks the interaction of VEGFR2 with its natural ligand vascular endothelial growth factor and subsequent autophosphorylation, signaling, and pro-angiogenic activation of endothelial cells in vitro. UniPR1331 also inhibits tumor cell-driven angiogenesis in zebrafish [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809170-59-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-123927. | |
| Unlabeled FXX489 | Unlabeled FXX489 (NNS309) is a fibroblast activation protein (FAP)-targeting ligand. Unlabeled FXX489 can be labeled with 68Ga and 177Lu and shows anticancer effects. Unlabeled FXX489 can be used for the study of pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), breast cancer (BC), and colorectal cancer (CRC)[1]. Uses: Scientific research. Group: Peptides. Alternative Names: NNS309. CAS No. 3076330-05-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10944. | |
| Unoprostone | Unoprostone, a prostaglandin F2α analogs (PGAs), activates BK channels to reduce oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and is used topically for glaucoma or ocular hypertension [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120373-36-6. Pack Sizes: 1 mg (26.14 mM * 100 μL in Methyl acetate). Product ID: HY-106916. | |
| Upacicalcet sodium | Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2052969-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109106A. | |
| Upadacitinib | Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 ( JAK1 ) inhibitor ( IC 50 =43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-494. CAS No. 1310726-60-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19569. | |
| Upamostat | Upamostat (WX-671) is a serine protease inhibitor. Upamostat is the orally available prodrug of the WX-UK1, which is a urokinase plasminogen activator (uPA) inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WX-671. CAS No. 590368-25-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16511. | |
| UPF 1069 | UPF 1069 is a PARP inhibitor, with IC50s of 8 and 0.3 ?M for PARP-1 and PARP-2, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1048371-03-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14478. | |
| Upidosin | Upidosin (Rec 15/2739) is an α-1 adrenoceptor ( α-1 AR ) antagonist. Upidosin shows moderate selectivity for the α-1A AR subtype. Upidosin shows uroselectivity in urethra and prostate with a K b value of 2-3 nM higher than in ear artery and aorta with a K b value of 20-100 nM. Upidosin inhibits [3H]prazosin binding to cloned human α-1A adrenergic receptor. Upidosin can be used for the research of urethral obstruction [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Rec 15/2739; Recordati 15/2739; SB 216469. CAS No. 152735-23-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106954. | |
| Upifitamab | Upifitamab is an ADC Antibody (a naked antibody of upifitamab rilsodotin), which can be used for antibody-coupled agent (ADC) synthesis. Upifitamab rilsodotin is an ADC targeting NaPi2b and is used in ovarian cancer research, particularly in platinum-resistant recurrent ovarian cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2254118-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99229. | |
| Uplarafenib | Uplarafenib (B-Raf IN 10) (Compound C09) is a BRAF inhibitor with an IC 50 between 50 and 100 nM. Uplarafenib shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B-Raf IN 10. CAS No. 1425485-87-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148059. | |
| Uprifosbuvir | Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IDX21437; MK-3682. CAS No. 1496551-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103487. | |
| Uprosertib | Uprosertib (GSK2141795) is a potent and selective pan-Akt inhibitor with IC 50 values of 180/328/38 nM for Akt1/Akt2/Akt3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK2141795. CAS No. 1047634-65-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15965. | |
| Urabrelimab | Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SRF-231; SRF231. CAS No. 2249722-58-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99533. | |
| Uracil | Uracil is a pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. Uracil is a frequently occurring DNA base damage that results from the spontaneous or chemically induced deamination of cytosine and is mutagenic at the level of replication. Uracil could potentially alter transcriptional fidelity, resulting in production of mutant proteins [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 66-22-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-I0960. | |
| Urapidil | Urapidil is an α1 adrenoreceptor antagonist and a 5-HT 1A receptor agonist. Uses: Scientific research. Group: Signaling pathways. CAS No. 34661-75-1. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-B0716. | |
| Urapidil hydrochloride | Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT 1A receptor agonist with a p IC 50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64887-14-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0354A. | |
| Urapidil (hydrochloride) (Standard) | Urapidil (hydrochloride) (Standard) is the analytical standard of Urapidil (hydrochloride). This product is intended for research and analytical applications. Urapidil hydrochloride is an orally active α1-adrenoceptor antagonist and 5-HT 1A receptor agonist with a p IC 50 of 6.13 and 4.38 against α1- and α2-adrenoceptor, respectively. Urapidil hydrochloride shows antihypertensive effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 64887-14-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0354AR. | |
| URAT1 inhibitor 8 | URAT1 inhibitor 8 (example 247) is a potent URAT1 inhibitor, with an IC 50 of 0.001 μM. URAT1 inhibitor 8 can be used for gout research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1632005-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153971. | |
| URAT1&XO inhibitor 1 | URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 ( IC 50 =~10 μM) and Xanthine Oxidase ( IC 50 =1.01 μM). URAT1&XO inhibitor 1 results hypouricemic effect in potassium oxonate-induced hyperuricemia rat model. URAT1&XO inhibitor 1 is used for hyperuricemia research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2669726-78-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-153968. | |
| URAT1&XO inhibitor 2 | URAT1&XO inhibitor 2 (Compound BDEO) is a dual inhibitor of xanthine oxidase and URAT1 , with IC 50 of 3.3 μM for xanthine oxidase. URAT1&XO inhibitor 2 blocks uptake of uric acid in HEK293 cells expressing URAT1, with a K i value of 0.145 μM. URAT1&XO inhibitor 2 decreases serum urate level and uric acid excretion in hyperuricemic mice. URAT1&XO inhibitor 2 can be used for research of hyperuricemia [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1239488-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153972. | |
| Urate oxidase, Microorganism | Urate oxidase, Microorganism (Uox), i.e., uricase, is often used in biochemical studies. Urate oxidase is a peroxisomal enzyme that catalyzes the oxidation of uric acid to allantoin in most mammals [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uox. CAS No. 9002-12-4. Pack Sizes: 1 KU; 5 KU. Product ID: HY-P2921. | |
| URB-597 | URB-597 (KDS-4103) is an orally bioavailable and selective FAAH inhibitor. URB-597 inhibits FAAH activity with an IC 50 s of approximately 5 nM in rat brain membranes, 0.5 nM in intact rat neurons, 3 nM in human liver microsomes. Antidepressant-like effects. Analgesic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KDS-4103. CAS No. 546141-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10864. | |
| Urea | Urea is a powerful protein denaturant via both direct and indirect mechanisms [1]. A potent emollient and keratolytic agent [2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function [3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Uses: Scientific research. Group: Natural products. Alternative Names: Carbonyl diamide. CAS No. 57-13-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 5 g. Product ID: HY-Y0271. | |
| Urea-13C | Urea- 13 C is the 13 C labelled urea. The Urea- 13 C breath test ( 13 C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 58069-82-2. Pack Sizes: 1 mg; 50 mg; 100 mg. Product ID: HY-118877. | |
| Urea-13C,15N2 | Urea- 13 C, 15 N 2 is the 13 C and 15 N labeled Urea[1]. Urea is a powerful protein denaturant via both direct and indirect mechanisms[1]. A potent emollient and keratolytic agent[2]. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function[3]. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 58069-83-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-Y0271S2. | |
| Urease, Jack bean | Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-13-5. Pack Sizes: 10 KU; 20 KU. Product ID: HY-P2767. | |
| Ureidopropionic acid | Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in the metabolism of uracil. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Ureidopropionic acid. CAS No. 462-88-4. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113285. | |
| Urelumab | Urelumab, a fully human, non-ligand binding, CD137 agonist IgG4 monoclonal antibody, enhances T-cell and natural killer-cell antitumor activity, and may enhance cytotoxic activity of Rituximab (HY-P9913). Urelumab can be used for the research of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL)[1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 934823-49-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99055. | |
| Urethane | Urethane (Ethyl carbamate), the ethyl ester of carbamic acid, is a byproduct of fermentation found in various food products. Urethane has the ability to suppress bacterial , protozoal , sea urchin egg, and plant tissue growth in vitro [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Ethyl carbamate; Carbamic acid ethyl ester; Ethylurethane. CAS No. 51-79-6. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-B1207. | |
| Uric acid | Uric acid, scavenger of oxygen radical , is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 69-93-2. Pack Sizes: 500 mg; 1 g. Product ID: HY-B2130. | |
| Uric acid sodium | Uric acid sodium (Monosodium urate), scavenger of oxygen radical , is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid sodium can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Monosodium urate. CAS No. 1198-77-2. Pack Sizes: 200 mg. Product ID: HY-B2130A. | |
| Uric acid (Standard) | Uric acid (Standard) is the analytical standard of Uric acid. This product is intended for research and analytical applications. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 69-93-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B2130R. | |
| Uricase (Recombinant) | Uricase, Arthrobacter globiformis is a peroxidase enzyme responsible for catalyzing the oxidative reaction of uric acid, converting it into the soluble product allantoin. Uricase, Arthrobacter globiformis can be used for the determination of uric acid levels in serum. The lack of uricase in mammals can lead to kidney diseases caused by the accumulation of uric acid. Uricase, Arthrobacter globiformis can be utilized in research on gout and hyperuricemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Uox (Recombinant). CAS No. 9002-12-4. Pack Sizes: 1 KU. Product ID: HY-P2921C. | |
| Uridine | Uridine (β-Uridine) is a nucleoside compound composed of uracil and a ribose ring, which are connected by a β-N1-glycosidic bond [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-Uridine. CAS No. 58-96-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1449. | |
| Uridine-5'-diphosphate disodium salt | Uridine-5'-diphosphate disodium salt is a potent, selective P2Y 6 receptor native agonist ( EC 50 =300 nM; pEC 50 =6.52 for human P2Y 6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite , catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 27821-45-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W010832. | |
| Uridine 5'-monophosphate | Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-Uridylic acid. CAS No. 58-97-9. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-101981. | |
| Uridine 5'-monophosphate disodium salt | Uridine 5'-monophosphate disodium salt is component used for RNA synthesis. Uses: Scientific research. Group: Natural products. CAS No. 3387-36-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-W013175. | |
| Uridine 5'-monophosphate (Standard) | Uridine 5'-monophosphate (Standard) is the analytical standard of Uridine 5'-monophosphate. This product is intended for research and analytical applications. Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea. Uses: Scientific research. Group: Natural products. Alternative Names: 5'-Uridylic acid (Standard). CAS No. 58-97-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101981R. | |
| Uridine (Standard) | Uridine (Standard) is the analytical standard of Uridine. This product is intended for research and analytical applications. Uses: Scientific research. Group: Natural products. CAS No. 58-96-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1449R. | |
| Uridine triacetate | Uridine triacetate (Tri-O-acetyl uridine) is an orally active proagent of Uridine (HY-B1449). Uridine triacetate is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate is used for the research of 5-fluorouracil (5-FU) and capecitabine toxicity, or early-onset cardiac or central nervous system (CNS) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tri-O-acetyl uridine. CAS No. 4105-38-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-14905. | |
| Uridine triphosphate trisodium salt | Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors[1][2]. Uses: Scientific research. Group: Natural products. Alternative Names: UTP trisodium salt; Uridine 5'-triphosphate trisodium salt. CAS No. 19817-92-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W013093. | |
| URMC-099 | URMC-099 is an orally bioavailable and potent mixed lineage kinase type 3 (MLK3) (IC50=14 nM) inhibitor with with excellent blood-brain barrier penetration properties. Uses: Scientific research. Group: Signaling pathways. CAS No. 1229582-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12599. | |
| Urocanic acid | Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR). Uses: Scientific research. Group: Natural products. CAS No. 104-98-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-113008. | |
| Urocortin, human | Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF 2 receptor , with K i s of 0.4, 0.3, and 0.5 nM for hCRF 1 , rCRF 2α and mCRF 2β , respectively. Uses: Scientific research. Group: Peptides. Alternative Names: Urocortin (human); Human urocortin; Human urocortin 1; Human urocortin I. CAS No. 176591-49-4. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1295. | |
| Urocortin III, mouse TFA | Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2[1]. Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in the medial amygdala regulate complex social dynamics[2]. Uses: Scientific research. Group: Peptides. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1858A. | |
| Uroguanylin (human) | Uroguanylin (human) is a natural ligand for the Guanylyl Cyclase (GCC) receptor expressed in metastatic colorectal cancer tumors. Uroguanylin (human) has anti-tumor actions in an animal model for human colon cancer[1][2]. Uses: Scientific research. Group: Peptides. CAS No. 154525-25-4. Pack Sizes: 500 ?g; 1 mg; 5 mg. Product ID: HY-P3099. | |
| Urokinase, Human urine | Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase. CAS No. 9039-53-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-108904. | |
| Urolithin A | Urolithin A, a gut-microbial metabolite of ellagic acid, exerts anti-inflammatory, antiproliferative, and antioxidant properties. Urolithin A induces autophagy and apoptosis , suppresses cell cycle progression, and inhibits DNA synthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1143-70-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100599. | |
| Urolithin B | Urolithin B is one of Ellagitannins' slow microbial products, and has anti-inflammatory and anti-inflammatory effects. Urolithin B suppresses NF-κB activity. Urolithin B suppresses JNK , ERK and Akt 's oxidation, and increases AMPK 's oxidation. Urolithin B is also a quantitative change factor for bone and skin quality [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 1139-83-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-126307. | |
| Urolithin C | Urolithin C, a gut-microbial metabolite of Ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is a L-type Ca2+ channel opener and enhances Ca2+ influx. Urolithin C induces cell apoptosis through a mitochondria-mediated pathway and also stimulates reactive oxygen species (ROS) formation[1][2]. Uses: Scientific research. Group: Natural products. CAS No. 165393-06-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-135897. | |
| Urolithin D | Urolithin D (3,4,8,9-Tetrahydroxy urolithin) is a colonic metabolite of Ellagitannins and a competitive, reversible, and selective antagonist of the EphA receptor. Urolithin D inhibits EphA2-ephrin-A1 binding with an IC50 of 0.9 ?M. Urolithin D is also a potent antioxidant that scavenges free radicals and repairs oxidized DNA damage. Additionally, Urolithin D suppresses triglyceride accumulation and promotes fatty acid oxidation by activating the AMPK signaling pathway. Urolithin D can be used for research on tumors, metabolic, and inflammatory diseases[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4,8,9-Tetrahydroxy urolithin. CAS No. 131086-98-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133178. | |
| Urolithin E | Urolithin E is a biological molecule. Uses: Scientific research. Group: Signaling pathways. CAS No. 1453297-45-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W746164. | |
| Urotensin II-related peptide | Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 342878-90-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1165. | |
| Ursocholic acid | Ursocholic acid, a bile acid present in mammalian bile, is converted to deoxycholic acid (UDC) by the mouse intestinal flora. Ursocholic acid acts as a gallstone dissolving agent in the liver through anti- apoptosis , anti-inflammatory, immunomodulatory, bile regulation, and coordinated changes in mitochondrial integrity and cell signaling, Ursocholic acid also has favorable effects on bones in patients with chronic cholestasis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 2955-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113212. | |
| Ursodeoxycholic acid | Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate; Ursodiol; UDCA. CAS No. 128-13-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-13771. | |
| Ursodeoxycholic acid-2,2,4,4-d4 | Ursodeoxycholic acid-2,2,4,4-d 4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 347841-46-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-113478S. | |
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.