MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| viFSP1 | viFSP1 is a species-independent FSP1 inhibitor. viFSP1 directly inhibits FSP1 by targeting the highly conserved NAD(P)H binding pocket of FSP1. viFSP1 can induce Ferroptosis in FSP1-dependent cells. viFSP1 can be used in renal and breast cancer research[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 951945-67-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-163002. |  |
| Vigabatrin | Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Vinyl-GABA. CAS No. 68506-86-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15399. | |
| Vigabatrin hydrochloride | Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Vinyl-GABA hydrochloride. CAS No. 1391054-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0033. | |
| Vilagletistat | ZED-1227 is a specific and orally active transglutaminase 2 (TG2) inhibitor, with an IC50 of 45 nM. ZED-1227 can block inflammation-induced TG2 expression and activity. ZED-1227 can be used for the research of celiac disease (CeD)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ZED-1227. CAS No. 1542132-88-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19359. | |
| Vilanterol | Vilanterol (GW642444) is a long-acting β 2 -adrenoceptor (β 2 -AR) agonist with 24 h activity. The pEC 50 s for β 2 -AR,β 1 -AR and β 3 -AR is 10.37±0.05, 6.98±0.03 and 7.36±0.03, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW642444. CAS No. 503068-34-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14300. | |
| Vilanterol trifenatate | Vilanterol trifenatate (GW642444 trifenatate) is a long-acting β 2 -adrenoceptor (β 2 -AR) agonist with inherent 24-hour activity. The pEC 50 s for β 2 -AR, β 1 -AR and β 3 -AR are 10.37, 6.98 and 7.36, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GW642444 trifenatate. CAS No. 503070-58-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14300A. | |
| Vilaprisan | Vilaprisan is a selective progesterone receptor modulator (SPRM), which targets progesterone receptors. Vilaprisan can inhibit cell proliferation and stimulate apoptosis. Vilaprisan has oral efficacy and anti-proliferative activity against uterine leiomyoma (UF [1] ). Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1002670. CAS No. 1262108-14-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-16775. | |
| Vilastobart | Vilastobart is an anti- CTLA4 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2760549-50-4. Pack Sizes: 1 mg. Product ID: HY-P990775. | |
| Vilazodone | Vilazodone (EMD 68843; SB 659746A) is a potent, selective and orally active serotonin reuptake inhibitor (SSRI) and partial 5-HT 1 A receptor agonist. Vilazodone exhibits antidepressant efficacy in vivo can be used for the research of major depressive disorder (MDD) and affective disorders [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 68843; SB659746A. CAS No. 163521-12-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14262. | |
| Vilazodone Hydrochloride | Vilazodone Hydrochloride (EMD 68843 Hydrochloride) is a serotonin transporter (SER) inhibitor and 5-HT 1A receptor partial agonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EMD 68843 Hydrochloride; SB659746A Hydrochloride. CAS No. 163521-08-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14261. | |
| Vildagliptin | Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV ( DPP-IV ) inhibitor with an IC 50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LAF237; NVP-LAF 237. CAS No. 274901-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-14291. | |
| Villocarine A | Villocarine A is a natural vasorelaxant indole alkaloid [1]. Uses: Scientific research. Group: Natural products. CAS No. 1319743-81-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N11478. | |
| Vilobelimab | Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti- C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CaCP-29, IFX-1. CAS No. 2250440-41-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99520. | |
| Viloxazine | Viloxazine (Viloxazin) is a norepinephrine reuptake inhibitor, also a potent 5-HT 2C agonist and 5-HT 2B antagonist with an EC 50 of 32 μM and an IC 50 of 27 μM for 5-HT 2C and 5-HT 2B , respectively. The mechanism of action of Viloxazine predominantly involves serotonergic and noradrenergic pathways. Viloxazine can be used for researching depression [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Viloxazin; Emovit. CAS No. 46817-91-8. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W380450. | |
| Viloxazine hydrochloride | Viloxazine hydrochloride is a non-brain-penetrant, selective norepinephrine transporter (NET) inhibitor ( IC 50 =0.26 μM) and 5-HT receptor modulator. Viloxazine antagonizes 5-HT2B receptors ( K i =4.2 μM) and agonizes 5-HT2C receptors ( EC 50 =32 μM), respectively, and enhances 5-HT neurotransmission by modulating 5-HT2B/C receptors. Viloxazine also competitively inhibits NET from increasing NE and DA levels in the synaptic cleft, and can be used in the study of attention deficit hyperactivity disorder (ADHD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Viloxazin hydrochloride; Emovit hydrochloride. CAS No. 35604-67-2. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125784. | |
| Viltolarsen sodium | Viltolarsen (NS-065/NCNP-01) sodium is a phosphorodiamidate morpholino antisense oligonucleotide. Viltolarsen sodium binds to exon 53 of the dystrophin mRNA precursor and restores the amino acid open-reading frame by skipping exon 53, resulting in the production of a shortened dystrophin protein that contains essential functional portions. Viltolarsen sodium has the potential for Duchenne muscular dystrophy (DMD) research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NS-065/NCNP-01 sodium. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132586A. | |
| Vimseltinib | Vimseltinib (DCC-3014) is a c-FMS ( CSF-IR ) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC 50 s of <0.01 μM and 0.1-1 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DCC-3014. CAS No. 1628606-05-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136256. | |
| Vinblastine sulfate | Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC 50 of 8.9 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Vincaleukoblastine sulfate salt. CAS No. 143-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13780. | |
| Vinburnine | Vincamone is a vinca alkaloid and a metabolite of vincamine, is a vasodilator. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Eburnamonine; (-)-Vincamone. CAS No. 4880-88-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg. Product ID: HY-B1180. | |
| Vincamine | Vincamine is a monoterpenoid indole alkaloid extracted from the Madagascar periwinkle. Vincamine is a peripheral vasodilator and exerts a selective vasoregulator action on the brain microcapilar circulation [1]. Vincamine is a GPR40 agonist and acts as a β-cell protector by ameliorating β-cell dysfunction and promoting glucose-stimulated insulin secretion (GSIS). Vincamine improves glucose homeostasis in vivo , and has the potential for the type 2 diabetes mellitus (T2DM) research [2]. Uses: Scientific research. Group: Natural products. CAS No. 1617-90-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B1021. | |
| Vincristine sulfate | Vincristine sulfate is an antitumor vinca alkaloid which inhibits microtubule formation in mitotic spindle, resulting in an arrest of dividing cells at the metaphase stage. It binds to microtubule with a K i of 85 nM. Uses: Scientific research. Group: Natural products. Alternative Names: Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate. CAS No. 2068-78-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-N0488. | |
| Vindesine sulfate | Vindesine sulfate is a potent tubulin inhibitor with an K i of 0.110 μM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo [1]. Uses: Scientific research. Group: Natural products. CAS No. 59917-39-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129071. | |
| Vindoline | Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus , weakly inhibits tubulin self-assembly [1]. Uses: Scientific research. Group: Natural products. CAS No. 2182-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg. Product ID: HY-N0687. | |
| Vinorelbine ditartrate | Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC 50 of 1.25 nM. Uses: Scientific research. Group: Natural products. Alternative Names: KW-2307; Nor-5'-anhydrovinblastine ditartrate. CAS No. 125317-39-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12053A. | |
| Vinpocetine | Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC 50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB -dependent inflammatory responses by directly targeting IκB kinase complex (IKK) , and has been widely used for the treatment of cerebrovascular disorders [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ethyl apovincaminate. CAS No. 42971-09-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13295. | |
| Vinyl-L-NIO hydrochloride | Vinyl-L-NIO hydrochloride is a potent nitric oxide synthase (NOS) inhibitor. Vinyl-L-NIO hydrochloride inhibits the activity of NOS, reducing the production of nitric oxide [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 728944-69-2. Pack Sizes: 5 mg. Product ID: HY-130579. | |
| Violuric acid | Violuric acid is a redox mediator used in the laccase system. The violuric acid assay is a method to ascertain that the high-redox potential of laccase is not lost during directed evolution [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 87-39-8. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-W097009. | |
| VIP(Guinea pig) | VIP Guinea pig (Vasoactive intestinal peptide), a trophic and mitogenic factor, stimulates growth in whole cultured embryos. VIP Guinea pig functions as a simple gastrointestinal hormone and suggest a possible neurotransmitter function [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Vasoactive Intestinal Peptide, guinea pig. CAS No. 96886-24-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1015. | |
| VIPhyb | VIPhyb (compound VIPhyb) is a vasoactive intestinal polypeptide (VIP) receptor antagonist that can be used in the study of cancers such as non-small cell lung cancer (NSCLC)[1]. Uses: Scientific research. Group: Peptides. CAS No. 125093-93-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5005. | |
| Vipivotide tetraxetan | Vipivotide tetraxetan (PSMA-617) is a high potent prostate-specific membrane antigen (PSMA) inhibitor, with a K i of 0.37 nM. Vipivotide tetraxetan (PSMA-617) is designed consisting of three components: the pharmacophore Glutamate-urea-Lysine, the chelator DOTA able to complex both 68Ga or 177Lu, and a linker connecting these two entities. Glutamate-urea-Lysine is the selective pharmacophore to bind to prostate specific membrane antigen. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PSMA-617. CAS No. 1702967-37-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-117410. | |
| Vipoglanstat | Vipoglanstat (BI 1029539), a carboxamide, is a potent and selective, non-peptide and orally active small molecular inhibitor of human prostaglandin E synthase 1 (mPGES-1). Vipoglanstat also has anti-inflammatory activity[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 1029539; GS-248; OX-MPI. CAS No. 1360622-01-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147416. | |
| Virginiamycin M1 | Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae , is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) [1]. Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL. Uses: Scientific research. Group: Natural products. Alternative Names: Pristinamycin IIA; Ostreogrycin A. CAS No. 21411-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6686. | |
| Virodhamine | Virodhamine is an endocannabinoid, it regulates neurotransmission by activating the cannabinoid (CB) receptors. Virodhamine is an antagonist of CB1 receptor and an agonist of CB2 receptor. Virodhamine induces megakaryocytic differentiation by triggering MAPK signaling and ROS production. Virodhamine can be used for the research of various neurological disorders such as Alzheimer's and Parkinson's diseases [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 287937-12-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116418. | |
| Virstatin | Virstatin inhibits the pili system synthesis and prevents A. baumannii biofilm formation. Virstatin also inhibits dimerization of the transcriptional activator ToxT [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 88909-96-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-127041. | |
| Visilizumab | Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD3E Recombinant Antibody; HuM291. CAS No. 219716-33-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99332. | |
| Vismodegib | Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC 50 of 3 nM. Vismodegib also inhibits P-gp , ABCG2 with IC 50 values of 3.0 μM and 1.4 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0449. CAS No. 879085-55-9. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10440. | |
| Visnagin | Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 82-57-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N1082. | |
| Visomitin | Visomitin (SKQ1) is a mitochondrial-targeted antioxidant with the high mitochondrion membrane penetrating ability and potent antioxidant capability[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKQ1. CAS No. 934826-68-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100474. | |
| Vistusertib | Vistusertib (AZD2014) is an ATP competitive mTOR inhibitor with an IC 50 of 2.81 nM. AZD2014 inhibits both mTORC1 and mTORC2 complexes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD2014. CAS No. 1009298-59-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15247. | |
| Visugromab | Visugromab (CTL-002) is a GDF-15 neutralizing IgG4 mAb. Visugromab has synergistic anticancer activity with the anti-PD1 antibody Nivolumab (HY-P9903) and can effectively act on PD-1/PD-L1 relapsed/refractory metastatic solid tumors [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CTL-002. CAS No. 2556646-63-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99100. | |
| VIT-2763 | VIT-2763, an oral ferroportin inhibitor, inhibits hepcidin binding to ferroportin and blocks iron efflux. VIT-2763 has the potential in the treatment of ?-thalassemia[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2095668-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112220. | |
| Vitamin A | Vitamin A (Vitamin A1) is an endogenous metabolite. Uses: Scientific research. Group: Natural products. Alternative Names: Vitamin A1; all-trans-Retinol. CAS No. 68-26-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1342. | |
| Vitamin B12 | Vitamin B12 is a vitamin. Vitamin B12 plays a key role in the normal functioning of the brain and nervous system, and for the formation of blood. Vitamin B12 is beneficial for many inflammatory diseases and also provides protection in oxidative-stress-associated pathologies [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Cyanocobalamin. CAS No. 68-19-9. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0315. | |
| Vitamin B1 monophosphate chloride | Vitamin B1 monophosphate (Thiamine monophosphate) chloride is a source of vitamin B1 and can be used in food supplements to enhance nutrition [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Thiamine monophosphate chloride. CAS No. 532-40-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1701. | |
| Vitamin B6 | Vitamin B6 is a potent antioxidant. Vitamin B6 is a suitable cofactor for many biochemical processes due to its water solubility and high reactivity when phosphorylated. Vitamin B6 is essential for the cellular metabolism and well-being of all living organisms [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 8059-24-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-150525. | |
| Vitamin D2 | Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ergocalciferol; Calciferol; Ercalciol. CAS No. 50-14-6. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-76542. | |
| Vitamin D2-d3 | Vitamin D2-d 3 (Ergocalciferol-d 3 ) is the deuterium labeled vitamin D2. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Ergocalciferol-d3; Calciferol-d3; VD2-d3. CAS No. 1217448-46-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-15330. | |
| Vitamin D3 | Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. Uses: Scientific research. Group: Natural products. Alternative Names: Cholecalciferol; Colecalciferol. CAS No. 67-97-0. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-15398. | |
| Vitamin D3-d3 | Vitamin D3-d 3 is the deuterium labeled Vitamin D3. Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Cholecalciferol-d3; Colecalciferol-d3. CAS No. 80666-48-4. Pack Sizes: 100 μg; 1 mg. Product ID: HY-15398S3. | |
| Vitamin D4 | Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 22-Dihydroergocalciferol. CAS No. 511-28-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-75958. | |
| Vitamin K | Vitamin K, the blood-clotting vitamin, is important for the function of numerous proteins within the body, such as the coagulation factors, osteocalcin and matrix-Gla protein. Uses: Scientific research. Group: Natural products. CAS No. 12001-79-5. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-B2172. | |
| Vitamin K1 | Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: Phylloquinone; Phytomenadione. CAS No. 84-80-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0684. | |
| Vitamin K1 2,3-epoxide | Vitamin K1 2,3-epoxide is an inactive metabolite form of Vitamin K1 (HY-N0684), which is reduced to active vitamin by microsomal epoxide reductase in the vitamin K epoxide cycle. Vitamin K1 2,3-epoxide is involved in blood clotting [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25486-55-9. Pack Sizes: 1 mg. Product ID: HY-113164. | |
| Vitamin U chloride | Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: S-Methylmethionine sulfonium chloride. CAS No. 1115-84-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N2551. | |
| Vitexin | Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3681-93-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0013. | |
| Vitexin-2'-O-rhamnoside | Vitexin-2"-O-rhamnoside, a main flavonoid glycoside of the leaves of Cratagus pinnatifida Bge, contributes to the protection against H 2 O 2 -mediated oxidative stress damage and has potential to treat cardiovascular system diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 64820-99-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0534. | |
| Vitexin-4''-O-glucoside | Vitexin-4''-O-glucoside is a kind of flavonoid fraction from the leaves of Crataegus pinnatifida [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4''-O-Glucosylvitexin. CAS No. 178468-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N5073. | |
| Vixarelimab | Vixarelimab (KPL-716) is a human anti-oncostatin M ( OSM ) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KPL-716. CAS No. 2243320-83-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99519. | |
| VJDT | VJDT is a TREM1 inhibitor that can effectively block TREM1 signaling. VJDT inhibits tumor cell proliferation and migration and induces cell cycle arrest. VJDT has immunomodulatory and antitumor activities, and can be used for the research of tumors such as melanoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765319-65-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157122. | |
| VK-2019 | VK-2019 is an oral active, selective EBNA1 ((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2044520-06-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W725179. | |
| VK-28 | VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation, with an IC 50 of 12.7 μM. VK-28 exhibits significant neuroprotective effects on ICV-6-OHDA. VK-28 can be used for the research of Parkinsons disease and other neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312611-92-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W686216. | |
| VKGILS-NH2 | VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 942413-05-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1310. | |
| VLS-1272 | VLS-1272 (Compound 22) is an orally active KIF18A inhibitor that binds to the KIF18A-microtubule complex in an ATP-noncompetitive manner (IC50 = 41 nM), blocking its ATPase activity and inhibiting microtubule translocation. This leads to abnormal accumulation of KIF18A at spindle poles, disrupting chromosome alignment and inducing mitotic arrest and apoptosis in CINHigh tumor cells (e.g., ovarian cancer OVCAR-3, breast cancer JIMT-1). VLS-1272 is a promising candidate for anti-tumor research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KIF18A-IN-7. CAS No. 2914878-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153066. | |
| VLX1570 | VLX1570 is a competitive inhibitor of proteasome deubiquitinases (DUBs) with an IC50 of approximate 10 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431280-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12471. | |
| VLX600 | VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS). VLX600 causes mitochondrial dysfunction and induces a strong shift to glycolysis. VLX600 displays selective cytotoxic activity against malignant cell and induces autophagy. Anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 327031-55-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12406. | |
| Voacamine | Voacamine, an indole alkaloid, exhibits potent cannabinoid CB1 receptor antagonistic activity [1]. Voacamine also inhibits P-glycoprotein ( P-gp ) action in multidrug-resistant tumor cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 3371-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6932. | |
| Voacangine | Voacangine is an antagonist for TRPV1 and TRPM8 but as an agonist for TRPA1 ( EC 50 =8 μM). Voacangine competitively blockes capsaicin binding to TRPV1 ( IC 50 =50 μM). Voacangine competitively inhibits the binding of menthol to TRPM8 ( IC 50 =9 μM) and it shows noncompetitive inhibition against icilin ( IC 50 =7 μM). Voacangine selectively abrogates chemical agonist-induced TRPM8 activation and did not affect cold-induced activation. Voacangine is an alkaloid isolated from the root bark of Voacanga africana [1]. Uses: Scientific research. Group: Natural products. CAS No. 510-22-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7536. | |
| Vobarilizumab | Vobarilizumab (ALX-0061) is a humanized bispecific anti- IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) ( K d : 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALX-0061. CAS No. 1628814-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99385. | |
| Vobramitamab | Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. MGC018 displays potent antitumor activity in preclinical tumor models of breast, ovarian, and lung cancer, as well as melanoma [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AEX-4089. CAS No. 2490556-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99101. | |
| Vociprotafib | Vociprotafib (RMC-4630) is an orally active, selective and potent phosphatase SHP2 inhibitor, which blocks activation of the RAS-RAF-MEK-ERK signaling pathway with antitumor activity. Vociprotafib accelerates the time to, and increases the magnitude of, tumor regressions in Osimertinib (HY-15772)-sensitive EGFR-mutant tumors of mice[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMC-4630; SHP2-IN-7. CAS No. 2172652-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141523. | |
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