MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Wortmannin | Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC 50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC 50 s of 5.8 and 48 nM, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SL-2052; KY-12420. CAS No. 19545-26-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10197. |  |
| WP1066 | WP1066 is an inhibitor of JAK2 and STAT3 , and also shows effect on STAT5 and ERK1/2, without affecting JAK1 and JAK3. Uses: Scientific research. Group: Signaling pathways. CAS No. 857064-38-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15312. | |
| WP9QY | WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.). Uses: Scientific research. Group: Peptides. CAS No. 199999-60-5. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P2612. | |
| WR99210 | WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine (HY-18062)-resistant P. falciparum strains) as well as T. gondii[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BRL 6231 free base. CAS No. 47326-86-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116387. | |
| WRG-28 | WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1913291-02-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114169. | |
| Wright's stain | Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. Wright's stain is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates. Wright's stain provides a manual or automated stain for bone marrow and peripheral blood smears [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 68988-92-1. Pack Sizes: 5 g; 10 g. Product ID: HY-W088068. | |
| WRN inhibitor 8 | WRN inhibitor 8 (Example 224) is a WRN helicase inhibitor with IC 50 value of 48 nM. WRN inhibitor 8 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026502-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160859. | |
| WRR139 | WRR139 is a peptide vinyl sulfone involving in disease processes such as inflammation and cancer. WRR139 is also a cytosolic enzyme N-glycanase 1 (NGLY1) and Nrf1 inhibitor. WRR139 enhances Carfilzomib cytotoxicity against cancer cells[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2138924-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129225. | |
| WRW4 | WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC 50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide [1]. Uses: Scientific research. Group: Peptides. CAS No. 878557-55-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1119. | |
| WS6 | WS6 is an IkB kinase and EBP1 inhibitor, with IC 50 values of 0.24 nM, 0.21 nM, and 40.48 nM in MV4-11, MOLM13, and K562 cells, respectively. WS6 promotes the proliferation of alpha and beta cells in the pancreas, has antioxidant and anti-inflammatory activities, and can alleviate depression like behavior in rats [1][2][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421227-53-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12461. | |
| WSP-1 | WSP-1 is a selective and rapid-reaction H2S specific fluorescent dye (Ex/Em=465/515 nm). WSP-1 reacts with H2S with the releasing of fluorophore[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1352750-34-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-124409. | |
| WSP-5 | WSP-5 is a fluorescent probe for fast detection of H2S in biological samples and cells. WSP-5 selectively and rapidly reacts with H2S and exhibits fluorescence through a reaction-based fluorescent turn-on strategy. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1593024-78-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-129420. | |
| WST-1 | WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 150849-52-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136976. | |
| WST-3 | WST-3 is a water-soluble tetrazolium dye. In the presence of an electron mediator, WST-3 is reduced to WST-3 formazan by NADH and displays an absorption maxima of 433 nM [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 515111-36-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-125921. | |
| WST-8 | WST-8 is a water-soluble tetrazolium dye, WST-8 enhances sensitivity of the WST-8-based assay over the conventional MTS-based assay. Uses: Scientific research. Group: Fluorescent dye. CAS No. 193149-74-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-D0831. | |
| Wu-5 | Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD degradation and induce apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2630378-05-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153886. | |
| WYE-132 | WYE-132 (WYE-125132) is a highly potent, ATP-competitive, and specific mTOR kinase inhibitor (IC50: 0.19±0.07 nM; >5,000-fold selective versus PI3Ks). WYE-132 (WYE-125132) inhibits mTORC1 and mTORC2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WYE-125132. CAS No. 1144068-46-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10044. | |
| WZ4003 | WZ4003 is the first potent and highly specific NUAK kinase inhibitor with IC50 of 20 nM/100 nM for NUAK1 (ARK5)/NUAK2, without significant inhibition on other 139 kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 1214265-58-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15802. | |
| WZB117 | WZB117 is a glucose transporter 1 ( Glut1 ) inhibitor, which downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. CAS No. 1223397-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19331. | |
| X-34 | X-34 is a lipophilic and bright yellow-green fluorescent derivative of Congo red (HY-D0236). X-34 can be used to stain neuritic and diffuse plaques, neurofibrillary tangles (NFTs), neuropil threads, and cerebrovascular amyloid in the brain. X-34 can be used for research of Alzheimers disease [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 215294-98-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125962. | |
| Xaliproden hydrochloride | Xaliproden hydrochloride (SR57746A) is a potent, selective and orally active agonist of 5-HT 1A receptor , shows a high affinity for 5-HT 1A specific binding sites in the rat hippocampus ( IC 50 =3 nM). Xaliproden hydrochloride is also a selective antagonist of dopamine D 2 receptor , has moderate affinity ( IC 50 =0.1-1 μM). Xaliproden hydrochloride exhibits anti-depression and anti-anxiety effects, and it may possess therapeutic potential for the research of neurodegenerative diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR57746A; SR57746 hydrochloride. CAS No. 90494-79-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14604. | |
| X-alpha-Gal | X-alpha-Gal is a chromogenic substrate that is used to screen colonies with high activity of β-galactopyranoside [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107021-38-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114522. | |
| Xaluritamig | Xaluritamig is an anti- CD3E/STEAP1 monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2460399-39-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990688. | |
| Xamoterol hemifumarate | Xamoterol hemifumarate is a selective and potent agonist of beta1-adrenergic receptor. Xamoterol hemifumarate has the potential for the research of arrhythmogenesis. Xamoterol hemifumarate has the potential for the investigating the relationship between β1-adrenergic stimulation and IKr [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Corwin hemifumarate; ICI 118587 hemifumarate. CAS No. 73210-73-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101327A. | |
| Xanomeline | Xanomeline, as an effective and selective muscarinic type 1 and type 4 ( M1/M4 ) receptor agonist, increases neuronal excitability. Xanomeline can be used for the research of neurological disorders, such as schizophrenia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY-246708. CAS No. 131986-45-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105182. | |
| Xanomeline oxalate | Xanomeline oxalate (LY246708 oxalate) is a potent and selective muscarinic receptor agonist (SMRA) and stimulates phosphoinositide hydrolysis in vivo. Xanomeline oxalate can be used for the research of Alzheimers disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY246708 oxalate. CAS No. 141064-23-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13410. | |
| Xanomeline tartrate | Xanomeline (LY 246708) is the potent agonist of muscarinic M1/M4 receptor with antipsychotic-like activity. Xanomeline (LY 246708) increases neuronal excitability. Xanomeline (LY 246708) can be used for the research of schizophrenia [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY 246708 tartrate. CAS No. 152854-19-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105182A. | |
| Xanthan gum | Xanthan gum is a microbial polysaccharide produced by Xanthomonas campestris. The structure of xanthan gum is based on a cellulose backbone of β-(1-4)-linked glucose units with a trisaccharide side of mannose-glucuronic acid-mannose attached to every other glucose unit in the backbone chain. Some terminal mannose units are pyruvated and some internal mannose units are acetylated. Due to its unique rheology and gelling properties, it is widely used as a food additive, thickener and stabilizer in the food and petroleum industries. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 11138-66-2. Pack Sizes: 500 g. Product ID: HY-A0103. | |
| Xanthine | Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 69-89-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W017389. | |
| Xanthine oxidase, bovine milk | Xanthine oxidase, bovine milk is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-17-9. Pack Sizes: 5 U; 25 U; 100 U. Product ID: HY-P2755A. | |
| Xanthine oxidase, Microorganism | Xanthine oxidase, Microorganism (XO) is a xanthine oxidoreductase enzyme that generates reactive oxygen species (ROS), catalyzes the oxidation of hypoxanthine to xanthine, and further catalyzes the oxidation of xanthine to uric acid[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XO; XOD. CAS No. 9002-17-9. Pack Sizes: 100 U. Product ID: HY-P2755. | |
| Xanthine (Standard) | Xanthine (Standard) is the analytical standard of Xanthine. This product is intended for research and analytical applications. Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation [1] [2] [3]. In Vitro: A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Uses: Scientific research. Group: Natural products. CAS No. 69-89-6. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-W017389R. | |
| Xanthinol Nicotinate | Xanthinol Nicotinate (Xanthinol Niacinate), a vasodilator, can act directly on the smooth muscle of small arteries and capillaries. Xanthinol Nicotinate expands blood vessels, improves blood rheology and reduces peripheral vascular resistance [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Xanthinol Niacinate. CAS No. 437-74-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B1815. | |
| Xanthohumol | Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase ( DGAT ), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV) , rhinovirus , HSV-1 , HSV-2 and cytomegalovirus (CMV). Uses: Scientific research. Group: Natural products. CAS No. 6754-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-N1067. | |
| Xanthone | Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 90-47-1. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N0126. | |
| Xanthone (Standard) | Xanthone (Standard) is the analytical standard of Xanthone. This product is intended for research and analytical applications. Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 90-47-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0126R. | |
| Xanthorrhizol | Xanthorrhizol, isolated from Curcuma xanthorrhiza Roxb, is a potential antibacterial agent. Uses: Scientific research. Group: Natural products. CAS No. 30199-26-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 1 mg. Product ID: HY-112657. | |
| Xanthosine | Xanthosine is a nucleoside derived from xanthine and ribose. Xanthosine can increase mammary stem cell population and milk production in cattle and goats [1]. Uses: Scientific research. Group: Natural products. CAS No. 146-80-5. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-W011527. | |
| Xanthosine 5'-monophosphate sodium salt | Xanthosine 5'-monophosphate sodium salt (5'-Xanthylic acid sodium salt) is an intermediate in purine metabolism. Xanthosine 5'-monophosphate sodium salt can be used for genetic code, nucleic acid structure, and DNA, RNA and protein synthesis research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5'-Xanthylic acid sodium salt. CAS No. 25899-70-1. Pack Sizes: 50 mg; 100 mg. Product ID: HY-W008990. | |
| Xanthurenic acid | Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Uses: Scientific research. Group: Natural products. CAS No. 59-00-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W014666. | |
| Xanthurenic acid-d4 | Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1329611-28-0. Pack Sizes: 2.5 mg; 5 mg. Product ID: HY-W014666S. | |
| Xantphos | Xantphos (9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene. CAS No. 161265-03-8. Pack Sizes: 25 g. Product ID: HY-Y0091. | |
| XAP044 | XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 196928-50-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110146. | |
| XAV-939 | XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC 50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 284028-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15147. | |
| XCT790 | XCT-790 is a potent and selective inverse agonist for ERRα with an IC 50 value of 0.37 μM. XCT-790 induces cell death in chemotherapeutic resistant cancer cells. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 725247-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10426. | |
| XE991 dihydrochloride | XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1) , Kv7.2 (KCNQ2) , Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC 50 s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122955-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108577. | |
| Xeligekimab | Xeligekimab (GR 1501) is an anti- human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GR 1501. CAS No. 2382921-73-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99515. | |
| Xenin | Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake. Uses: Scientific research. Group: Peptides. CAS No. 144092-28-4. Pack Sizes: 500 μg; 5 mg; 10 mg. Product ID: HY-P0259. | |
| Xentuzumab | Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands IGF1 and IGF2. Xentuzumab inhibits both of IGF1 and IGF2 growth-promoting signalling and suppresses AKT activation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BI 836845; Anti-Human IGF1 and IGF2 Recombinant Antibody. CAS No. 1417158-65-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99274. | |
| Xeruborbactam disodium | Xeruborbactam (QPX7728) disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QPX7728 disodium. CAS No. 2170848-99-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136072. | |
| Xestospongin C | Xestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca2+ release from cerebellar microsomes with an IC50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca2+ signaling in neuronal and nonneuronal cells[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Xestospongin C. CAS No. 88903-69-9. Pack Sizes: 10 ?g. Product ID: HY-103312. | |
| Xevinapant | Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs , and it binds to XIAP, cIAP1, and cIAP2 proteins with K i of 66.4, 1.9, and 5.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-406; Debio 1143; SM-406. CAS No. 1071992-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15454. | |
| Xevinapant hydrochloride | Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with K i s of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-406 hydrochloride; Debio 1143 hydrochloride; SM-406 hydrochloride. CAS No. 1071992-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13208. | |
| X-GAL | X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BCIG. CAS No. 7240-90-6. Pack Sizes: 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-15934. | |
| X-Gluc cyclohexanamine | X-Gluc cyclohexanamine is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc cyclohexanamine can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc cyclohexanamine is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 114162-64-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15935B. | |
| X-Gluc Dicyclohexylamine | X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 18656-96-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-15935. | |
| X-Gluc sodium | X-Gluc sodium is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 129541-41-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15935C. | |
| XIE62-1004-A | XIE62-1004-A is an inducer of p62-LC3 interaction. XIE62-1004-A can bind to the ZZ-domain of p62, inducing p62 oligomerization and activating p62-dependent autophagy[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2421146-32-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W688687. | |
| Ximelagatran | Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 376/95. CAS No. 192939-46-1. Pack Sizes: 10 mM * 1 mL; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10787. | |
| Xipamide | Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14293-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-W042301. | |
| XL01126 | XL01126 is a potent LRRK2 PROTAC (DC50: 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2)) composed of the VHL ligand VH 101, thiol (HY-47851, blue part) and the LRRK2 inhibitor HG-10-102-01 (HY-13488, red part). XL01126 crosses the blood-brain barrier and is used as a degradation probe in Parkinson's disease research. XL01126 can be used to study the non-catalytic and framework functions of LRRK2[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3011029-58-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148030. | |
| XL019 | XL019?is a potent, orally active, and selective JAK2 inhibitor, with IC50s of 2.2, 134.3, and 214.2 nM for JAK2, JAK1 and JAK3, respectively. XL019 shows 50-fold or greater selectivity for JAK2, versus a panel of over 100 serine/threonine and tyrosine kinases, including other members of the JAK family. XL019 potently inhibits STAT3 and STAT5 phosphorylation in cells harboring either JAK2V617F or wild-type JAK2[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 945755-56-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-13775. | |
| XL177A | XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC50 of 0.34?nM. XL177A elicits cancer cell killing through a p53-dependent mechanism[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417089-74-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138794. | |
| XL 188 | XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively. XL 188 can be used in research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305045-76-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122886. | |
| XL413 | XL413 is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-863233. CAS No. 1169558-38-6. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-15260. | |
| XL413 monohydrochloride | XL413 (BMS-863233) hydrochloride is a potent, selective and ATP competitive inhibitor of Cdc7, with an IC50 of 3.4 nM, and also shows potent effect with IC50s of 215, 42 nM on CK2, PIM1, respectively, and an EC50 of 118 nM on pMCM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-863233 monohydrochloride. CAS No. 2062200-97-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15260A. | |
| XL44 | XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13 Pru and ubiquitin-independent loss of select KEN box containing proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2637949-91-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162393. | |
| XL888 | XL888 is a potent and orally active HSP90 inhibitor with an IC50 value of 24 nM. XL888 shows anti-proliferation activity and induces Apoptosis. XL888 shows anti-tumor activity[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1149705-71-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13313. | |
| XL 999 | XL999 is a multi-target tyrosine kinase inhibitor. XL999 has IC 50 values for KDR , Flt-1 , FGFR1 and PDGFRα of 4 nM, 20 nM, 4 nM and 2 nM, respectively. XL999 can be used in the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrosine kinase-IN-1. CAS No. 705946-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100315. | |
| XMD-17-51 TFA | XMD-17-51 TFA is a pyrimido-diazepinone compound that is able to modulate protein kinases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2436579-93-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-117291A. | |
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