MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Yohimbine Hydrochloride | Yohimbine hydrochloride is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis. Uses: Scientific research. Group: Natural products. CAS No. 65-19-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-N0127. |  |
| YQA14 | YQA14 is a high affinity dopamine D3 receptor antagonist. YQA14 is anti-opioid addiction agent. YQA14 inhibits Morphine/Cocaine-induced conditioned place preference (CPP) in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1221408-42-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-116181. | |
| YS 035 hydrochloride | YS 035 hydrochloride is a Ca 2+ antagonist on cellular uptake and mitochondrial efflux of calcium ions. YS 035 hydrochloride inhibits Ca 2+ uptake by muscle cells and inhibits Na + /Ca 2+ exchange ( K i =28 μM). YS 035 hydrochloride is a useful tool for research on the mitochondrial Ca 2+ transport [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89805-39-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100928. | |
| YTHDC1-IN-1 | YTHDC1-IN-1 is a selective YTHDC1 inhibitor with a Kd of 49 nM and an IC50 of 0.35 ?M. YTHDC1-IN-1 can inhibit the proliferation and induce apoptosis of acute myeloid leukemia cell lines. YTHDC1-IN-1 has anti-tumor activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2995344-53-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158974. | |
| YTK-105 | YTK-105 is a ligand of p62-ZZ domain. YTK-105 can activate p62-dependent selective macroautophagy. YTK-105 can be used for AUTOTAC design[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 774192-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W489121. | |
| YUM70 | YUM70 is a potent and selective inhibitor of glucose-regulated protein 78 (GRP78), with an IC50 of 1.5 ?M for inhibiting GRP78 ATPase activity of the full-length protein. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer. YUM70 also has in vivo efficacy in a pancreatic cancer xenograft model[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 423145-35-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138364. | |
| (Z)-3-Butylidenephthalide | (Z)-3-Butylidenephthalide is an antihyperglycemic agent by inhibiting the activity of intestinal and yeast R-glucosidases (IC 50 =2.35 mM; K i =4.86 mM) [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (Z)-Butylidenephthalide. CAS No. 72917-31-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0336A. | |
| Z57346765 | Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes in PGK1 glycolysis and inhibits PGK1-dependent cell proliferation. Z57346765 exerts inhibitory effects against clear cell renal cell carcinoma (KIRC)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1016340-64-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W195984. | |
| (Z)-9-Tricosene | (Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone present in flies of the order Diptera (such as the housefly) and can be used as an insecticide [1]. Uses: Scientific research. Group: Natural products. Alternative Names: cis-9-Tricosene. CAS No. 27519-02-4. Pack Sizes: 100 mg; 500 mg. Product ID: HY-W009165. | |
| Zabadinostat | Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC 50 s of 63 nM, 570 nM and 550 nM for HDAC1 , HDAC2 and HDAC3 , respectively. Zabadinostat has no activity against HDAC class II. Zabadinostat has antitumor activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CXD101. CAS No. 934828-12-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100748. | |
| Zabedosertib | Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-?, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1834845. CAS No. 1931994-81-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139374. | |
| Zabofloxacin hydrochloride | Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus , Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DW-224a. CAS No. 623574-00-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106410A. | |
| Zacopride hydrochloride | Zacopride hydrochloride is an orally active 5-HT 3 receptor ( K i of 0.38 nM) antagonist and 5-HT 4 receptor ( K i of 373 nM) agonist. Zacopride hydrochloride exhibits multiple activities, such as regulating gastrointestinal motility, affecting cardiac function, and exerting anxiolytic and antiemetic effects. Zacopride hydrochloride is currently mainly used in the research of gastrointestinal diseases, cardiovascular diseases, and psychiatric diseases such as anxiety [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [11]. Uses: Scientific research. Group: Signaling pathways. CAS No. 101303-98-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103137. | |
| Z-AEVD-FMK | Z-AEVD-FMK is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 1135688-47-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125305. | |
| Zafirlukast | Zafirlukast (ICI 204219) is a potent orally active leukotriene D 4 ( LTD 4 ) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI 204219. CAS No. 107753-78-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-17492. | |
| Zagotenemab | Zagotenemab (LY3303560) is a humanised anti- tau antibody that selectively binds and neutralises tau deposits in the brain. Zagotenemab can be used in Alzheimer's disease research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: LY33003560. CAS No. 2019133-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99164. | |
| Z-Ala-Ala-Asn-AMC | Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC[1]. Uses: Scientific research. Group: Peptides. Alternative Names: Cbz-Ala-Ala-Asn-AMC. CAS No. 149697-16-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136626. | |
| Z-Ala-Ala-Asp-CMK | Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: Z-AAD-CMK. CAS No. 183284-21-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10004. | |
| Z-Ala-Ala-OH | Z-Ala-Ala-OH is a non-polar amino acid that can be used in enzymatic peptide synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 16012-70-7. Pack Sizes: 1 g; 5 g. Product ID: HY-133803. | |
| Z-Ala-Arg-Arg-AMC | Z-Ala-Arg-Arg-AMC (Fluorogenic Proteasome Substrate) is a fluorogenic substrate for assaying trypsin-like activity of proteasome[1]. Uses: Scientific research. Group: Peptides. Alternative Names: Fluorogenic Proteasome Substrate; Z-ARR-AMC. CAS No. 90468-18-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-134961. | |
| Z-Ala-OMe | Z-Ala-OMe is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 28819-05-8. Pack Sizes: 25 g; 100 g. Product ID: HY-W012139. | |
| Z-Ala-OSu | Z-Ala-OSu is an alanine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 3401-36-3. Pack Sizes: 25 g; 100 g; 500 g. Product ID: HY-77132. | |
| Zalcitabine | Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2',3'-Dideoxycytidine; ddC; Dideoxycytidine. CAS No. 7481-89-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-17392. | |
| Zalifrelimab | Zalifrelimab (AGEN1884) is a fully human IgG1 monoclonal antibody targeting CTLA-4 ( CTLA-4 ). Zalifrelimab antagonizes the inhibitory checkpoints of immune cell activation regulated by CTLA-4 signaling [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AGEN1884. CAS No. 2148321-69-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99514. | |
| Zaltidine | Zaltidine dihydrochloride (CP-5736 dihydrochloride) is a highly specific H2 receptor antagonist with antisecretion activity. Zaltidine dihydrochloride reduces the stimulant effect of histamine on gastric acid secretion by binding to histamine H2 receptors on gastric parietal cells, thus reducing gastric acid production. Zaltidine dihydrochloride can be used in the study of gastric acid-related diseases such as duodenal ulcers [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-57361. CAS No. 85604-00-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15541. | |
| Zaltoprofen | Zaltoprofen (CN100), a non-steroidal anti-inflammatory drug (NSAID), is a preferential and orally active COX-2 inhibitor, with IC 50 s of 1.3 and 0.34 μM for COX-1 and COX-2 , respectively. Zaltoprofen exhibits powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CN100. CAS No. 74711-43-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0619. | |
| Zalunfiban dihydrochloride | Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist ( IC 50 =45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RUC-4 dihydrochloride. CAS No. 2815778-41-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119350B. | |
| Zalutumumab | Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC 50 s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 667901-13-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99155. | |
| Zamaporvint | Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RXC004. CAS No. 1900754-56-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153855. | |
| Zampilimab | Zampilimab (UCB-7858) is a monoclonal antibody against transglutaminase 2 ( TG2 ). Zampilimab has potential application in renal transplant [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: UCB-7858. CAS No. 2098280-42-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99512. | |
| Zanamivir | Zanamivir is an influenza viral neuraminidase inhibitor with IC 50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 139110-80-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13210. | |
| Zanapezil | Zanapezil (TAK-147) is a potent, reversible and selective acetylcholine esterase ( AChE ) inhibitor. Zanapezil shows a potent and reversible inhibition of AChE activity in homogenates of the rat cerebral cortex ( IC 50 =51.2 nM). Zanapezil shows a moderate inhibition of muscarinic M1 and M2 receptor binding with K i values of 234 and 340 nM, respectively. Zanapezil can be used for the research of early stages of Alzheimer's disease (AD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-147. CAS No. 142852-51-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-19651A. | |
| Zanapezil free base | Zanapezil (TAK-147) free base is a potent, reversible and selective acetylcholine esterase ( AChE ) inhibitor. Zanapezil free base shows a potent and reversible inhibition of AChE activity in homogenates of the rat cerebral cortex ( IC 50 =51.2 nM). Zanapezil free base shows a moderate inhibition of muscarinic M1 and M2 receptor binding with K i values of 234 and 340 nM, respectively. Zanapezil free base can be used for the research of early stages of Alzheimer's disease (AD) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-147 free base. CAS No. 142852-50-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-19651. | |
| Zandatrigine | Zandatrigine (NBI-921352; XEN901) is a selective, orally active, voltage-gated sodium channel NaV1.6/SCN8A inhibitor that can penetrate the blood-brain barrier. Zandatrigine inhibits sodium influx by non-covalently binding to the VSD4 structure of NaV1.6, blocking the persistent and resuscitative currents under pathological conditions. Zandatrigine can reduce neuronal hyperexcitability and reduce epileptic seizures. Zandatrigine is 134-756-fold selective for other isoforms such as NaV1.1 and NaV1.2, and has minimal effect on NaV1.1 expressed by inhibitory interneurons. Zandatrigine can be used to study NaV1.6-mediated neuroexcitability diseases such as SCN8A-related developmental epileptic encephalopathy (SCN8A-DEE) and adult focal epilepsy[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-921352; XEN901. CAS No. 2154406-04-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147423. | |
| Zandelisib | Zandelisib (ME-401) is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC 50 of 3.5 nM. Zandelisib functions as an antineoplastic [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ME-401; PWT-143. CAS No. 1401436-95-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109198. | |
| Zanidatamab | Zanidatamab (ZW25) is a humanised, bispecific monoclonal antibody targeting 2 distinct HER2 epitopes (ECD2 and ECD4). Zanidatamab has anti-tumour activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ZW 25. CAS No. 2169946-15-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99380. | |
| Zanolimumab | Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody targets CD4. Zanolimumab effectively inhibits T-cell receptor (TCR) signal transduction. Zanolimumab can be used for the research of heumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD4 Recombinant Antibody. CAS No. 652153-01-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99266. | |
| Zanubrutinib | Zanubrutinib (BGB-3111) is a selective and orally active Bruton tyrosine kinase ( Btk ) inhibitor ( IC 50 : 0.3 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BGB-3111. CAS No. 1691249-45-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101474A. | |
| (±)-Zanubrutinib | (±)-Zanubrutinib ((±)-BGB-3111) is the racemate of Zanubrutinib (HY-101474A). (±)-Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC 50 of 0.63 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-BGB-3111. CAS No. 1633350-06-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101474. | |
| Zanzalintinib | Zanzalintinib (XL092) is an orally active, ATP-competitive inhibitor of multiple receptor tyrosine kinases (RTKs) including MET , VEGFR2 , AXL and MER , with IC 50 s in cell-based assays of 15 nM, 1.6 nM, 3.4 nM, 7.2 nM respectively. Zanzalintinib exhibits anti-tumor activity. Zanzalintinib has the potential for kinase-dependent diseases and conditions research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL092. CAS No. 2367004-54-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138696. | |
| ZAP-180013 | ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 ?M. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 873080-25-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136179. | |
| ZAPA sulfate | ZAPA sulfate is an agonist at low affinity GABA A -receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC 50 of 10.3 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 371962-01-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100799. | |
| Zaprinast | Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5). Zaprinast causes a significant increase in cGMP levels in myocytes. Zaprinast is a G protein-coupled receptor 35 (GPR35) agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M&B 22948. CAS No. 37762-06-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1816. | |
| Zaragozic acid A | Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Squalestatin S1. CAS No. 142561-96-4. Pack Sizes: 1 mg. Product ID: HY-116290. | |
| Z-Arg-Arg-βNA acetate | Z-Arg-Arg-βNA acetate is a sensitive dipeptide substrate of the protease Cathepsin B and resistant to proteases H and L. Z-Arg-Arg-βNA acetate can serve as an important tool for distinguishing non-Cathepsin B type proteins [1]. Uses: Scientific research. Group: Peptides. CAS No. 2237216-27-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-158307. | |
| Zasocitinib | Zasocitinib (NDI-034858) is a TYK2 inhibitor, target TYK2 JH2 domain with binding constant K d of <200 pM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NDI-034858; TAK-279. CAS No. 2272904-53-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-150096. | |
| Z-Asp-OMe | Z-Asp-OMe is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 4668-42-2. Pack Sizes: 10 g; 25 g; 50 g; 100 g. Product ID: HY-W009328. | |
| Z-Asp(OMe)-OH | Z-Asp(OMe)-OH is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 3160-47-2. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W011553. | |
| Z-Asp(OtBu)-OH | Z-Asp(OtBu)-OH is an aspartic acid derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 5545-52-8. Pack Sizes: 25 g; 100 g; 500 g. Product ID: HY-W011278. | |
| Zastaprazan | Zastaprazan (JP-1366) is a proton pump inhibitor (WO2018008929). Zastaprazan can be used for the research of gastrointestinal inflammatory diseases or gastric acid-related diseases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JP-1366. CAS No. 2133852-18-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-139557. | |
| Zatolmilast | Zatolmilast (BPN14770) is a selective phosphodiesterase 4D (PDE4D) allosteric inhibitor with IC 50 s of 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BPN14770. CAS No. 1606974-33-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117571. | |
| Zavondemstat | Zavondemstat (QC8222; TACH 101) is an inhibitor of histone lysine demethylase 4D ( KDM4D ) with antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QC8222 free base; TACH 101 free base. CAS No. 1851412-93-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-148807. | |
| Zavondemstat L-lysine | Zavondemstat (QC8222; TACH 101) (L-lysine) is an inhibitor of histone lysine demethylase 4D ( KDM4D ) with antineoplastic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: QC8222; TACH 101. CAS No. 2908753-10-4. Pack Sizes: 1 mg. Product ID: HY-148807A. | |
| ZCZ011 | ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1998197-39-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-118140. | |
| ZD7288 | ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ICI D7288. CAS No. 133059-99-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101346. | |
| Z-DEVD-FMK | Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 210344-95-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12466. | |
| Zearalanone | Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species, which colonizes several grains. Zearalenone has low acute toxicity and carcinogenicity. Due to its agonistic effect on the estrogen receptor , Zearalenone exhibits distinct estrogenic and anabolic properties in several animal species, resulting in severe effects on the reproductive system [1]. Uses: Scientific research. Group: Natural products. CAS No. 5975-78-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6678. | |
| Zearalenone | Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Mycotoxin F2; Toxin F2. CAS No. 17924-92-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103447. | |
| Zearalenone-13C18 | Zearalenone- 13 C 18 (Mycotoxin F2- 13 C 18 ; Toxin F2- 13 C 18 ) is the 13 C labeled Zearalenone (HY-103447) [1]. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Mycotoxin F2- 13 C18; Toxin F2- 13 C18. CAS No. 911392-43-3. Pack Sizes: 30 μg (74.35 μM * 1.2 mL in Acetonitrile). Product ID: HY-103447S1. | |
| Zearalenone (Standard) | Zearalenone (Standard) is the analytical standard of Zearalenone. This product is intended for research and analytical applications. Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Mycotoxin F2(Standard); Toxin F2 (Standard). CAS No. 17924-92-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103447R. | |
| Zeaxanthin | Zeaxanthin, a diet-obtained carotenoid, presents in the macula region of the eye. Zeaxanthin shows antioxidant effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 144-68-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120318. | |
| Zebrafish Kisspeptin-1 | Zebrafish Kisspeptin-1 is the core sequence of the neuropeptide kisspeptin-1, which participate in the regulation of gonadotropin-releasing hormone (GnRH) release, and regulates the reproductive system [1]. Uses: Scientific research. Group: Peptides. CAS No. 1071873-79-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10419. | |
| Zebularine | Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. Zebularine also inhibits cytidine deaminase with a K i of 0.95 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC309132; 4-Deoxyuridine. CAS No. 3690-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13420. | |
| Zedoresertib | WEE1-IN-5 is a potent WEE1 inhibitor with an IC50 value of 0.8 nM. WEE1-IN-5 inhibits phospho-CDC2. WEE1-IN-5 abrogates the G2 check point, increasing sensitivity to DNA damaging agents in cancer cells. WEE1-IN-5 can be used for researching anticancer[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: WEE1-IN-5. CAS No. 2243882-74-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147054. | |
| Zegocractin | Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor, with IC50s of 119 nM and 895 nM for Orai1/STIM1 and Orai2/STIM1 channels, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM-4620. CAS No. 1713240-67-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101942. | |
| Zein | Zein is a plant protein?based polymer, can be used to prepare nanofibrous mats through electrospun. Zein has good cell compatibility and easy fabrication ability, and can be used in drug delivery systems [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 9010-66-6. Pack Sizes: 10 g; 25 g. Product ID: HY-W763806. | |
| Zelasudil | Zelasudil (RXC007) is an orally active, highly selective small molecule Rho-associated coiled-coil containing protein kinase 2 (ROCK2) inhibitor with anti-fibrotic efficacy. Zelasudil elicits positive immunomodulatory effects in metastatic pancreatic tumors with increase of CD8+ and CD4+ T cell infiltrate into the tumor cortex and reduction in immunosuppressive FOXP3+ regulatory T cells at the tumor border. Zelasudil is promising for research of pancreatic ductal adenocarcinoma[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RXC007. CAS No. 2365193-22-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148808. | |
| Zelatriazin | Zelatriazin (TAK-041; NBI-1065846) is a potent and selective GPR139 agonist with an EC50 of 22 nM. Zelatriazin has the potential for the research of negative symptoms associated with schizophrenia[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-041; NBI-1065846. CAS No. 1929519-13-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132228. | |
| Zelavespib | Zelavespib (PU-H71) is a potent Hsp90 inhibitor, with an IC 50 of 51 nM in MDA-MB-468 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PU-H71. CAS No. 873436-91-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11038. | |
| Zelavespib hydrochloride | Zelavespib (PU-H71) hydrochloride is a potent Hsp90 inhibitor, with an IC 50 of 51 nM in MDA-MB-468 cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PU-H71 hydrochloride. CAS No. 2095432-24-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11038B. | |
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