MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Velagliflozin | Velagliflozin is an orally available sodium-glucose cotransporter 2 ( SGLT2 ) inhibitor, with anti-diabetic activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 946525-65-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-109018. |  |
| Velagliflozin proline | Velagliflozin proline is an oral sodium-glucose cotransporter 2 ( SGLT2 ) inhibitor with antidiabetic activity. Velagliflozin proline reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1539295-26-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-109018A. | |
| Veldoreotide TFA | Veldoreotide (DG3173) TFA a somatostatin analogue, binds to and activate the somatostatin receptors (SSTR) 2, 4, and 5. Veldoreotide TFA inhibits growth hormone (GH) secretion in adenomas compared with Octreotide (HY-P0036). Veldoreotide has the potential to be used as pain modulating agent [1]. Uses: Scientific research. Group: Peptides. Alternative Names: DG3173 TFA; PTR-3173 TFA. CAS No. 2126831-23-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0024A. | |
| Veligrotug | Veligrotug is an IgG1-kappa, anti- IGF1R (insulin-like growth factor 1 receptor, CD221) chimeric monoclonal antibody [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2728655-31-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990084. | |
| Veliparib | Veliparib (ABT-888) is a potent PARP inhibitor, inhibiting PARP1 and PARP2 with K i s of 5.2 and 2.9 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-888. CAS No. 912444-00-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10129. | |
| Veliparib dihydrochloride | Veliparib (dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with K i s of 5.2 nM and 2.9 nM in cell-free assays, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-888 dihydrochloride. CAS No. 912445-05-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10130. | |
| Velnacrine maleate | Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HP 029; Hydroxytacrine maleate. CAS No. 118909-22-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W011246. | |
| Velneperit | Velneperit (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S2367. CAS No. 342577-38-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14423. | |
| Velpatasvir | Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons. Velpatasvir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 2.16 μM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5816. CAS No. 1377049-84-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12530. | |
| Veltuzumab | Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody. Veltuzumab has low EC 50 value of 0.08-0.09 μg/mL in the Daudi cell line. Veltuzumab can be used for the research of cancer including non-Hodgkin lymphoma (NHL) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMMU-106; hA20. CAS No. 728917-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99224. | |
| Velufenacin | Velufenacin is a muscarinic receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-8010. CAS No. 1648737-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109196. | |
| Velusetrag | Velusetrag (TD-5108) is an orally active, potent and selective agonist of serotonin 5-HT 4 receptor (5-HT4R) , with a pK i of 7.7. Velusetrag exhibits no affinity (K i >10 μM) for 5-HT 2A and 5-HT 2B receptors. Velusetrag can be used for the research of gastrointestinal diseases and Parkinson's disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-5108. CAS No. 866933-46-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10457. | |
| Velusetrag hydrochloride | Velusetrag (TD-5108) hydrochloride is an orally active, potent and selective agonist of serotonin 5-HT 4 receptor (5-HT 4 R) , with a pK i of 7.7. Velusetrag hydrochloride exhibits no affinity (K i >10 μM) for 5-HT 2A and 5-HT 2B receptors. Velusetrag hydrochloride can be used for the research of gastrointestinal diseases and Parkinson's disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-5108 hydrochloride. CAS No. 866933-51-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10457A. | |
| Velzatinib | Velzatinib (M4205) is a multi-target inhibitor for PDGFRB, PDGFRA, CSF1R, c-Kit, FLT3, and LCK, with an IC50s of 2.6, 50, 5.5, 44, 141 and 141 nM, respectively. Velzatinib exhibits antitumor efficacy in xenograft mouse models[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M4205; IDRX-42. CAS No. 2590556-80-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132166. | |
| Vemircopan | Vemircopan (ALXN2050) is an orally active complement factor D inhibitor. Vemircopan is promising for research of paroxysmal nocturnal hemoglobinuria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALXN2050; ACH 0145228; ACH-5228. CAS No. 2086178-00-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139588. | |
| Vemurafenib | Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC 50 s of 31 and 48 nM for RAF V600E and c-RAF-1, respectively [1] [4]. Vemurafenib induces cell autophagy [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX4032; RG7204; RO5185426. CAS No. 918504-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12057. | |
| Venetoclax | Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a K i of less than 0.01 nM. Venetoclax induces autophagy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-199; GDC-0199; RG7601. CAS No. 1257044-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15531. | |
| Venlafaxine | Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030. CAS No. 93413-69-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196. | |
| Venlafaxine-d6 | Venlafaxine-d 6 is the deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1020720-02-8. Pack Sizes: 5 mg. Product ID: HY-B0196S. | |
| Venlafaxine-d6 hydrochloride | Venlafaxine-d 6 (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Wy 45030-d6 hydrochloride. CAS No. 1062606-12-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-B0196AS1. | |
| Venlafaxine hydrochloride | Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030 hydrochloride. CAS No. 99300-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0196A. | |
| Venlafaxine hydrochloride (Standard) | Venlafaxine (hydrochloride) (Standard) is the analytical standard of Venlafaxine (hydrochloride). This product is intended for research and analytical applications. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030 hydrochloride (Standard). CAS No. 99300-78-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196AR. | |
| Vepdegestrant | Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration ( DC 50 ) of about 2 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARV-471. CAS No. 2229711-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138642. | |
| VER-155008 | VER-155008 is an inhibitor of Hsp70, with IC50s of 0.5 ?M, 2.6 ?M, and 2.6 ?M for Hsp70, Hsc70 and Grp7, respectively, and with a Kd of 0.3 ?M for Hsp70. Uses: Scientific research. Group: Signaling pathways. CAS No. 1134156-31-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10941. | |
| VER-246608 | VER-246608 is a potent and ATP-competitive inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50s of 35 nM, 40 nM, 84 nM, and 91 nM for PDK-1, PDK-3, PDK-2, and PDK-4, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1684386-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12492. | |
| VER-50589 | VER-50589 is a Hsp90 inhibitor, with an IC50 of 21 nM and a Kd of 4.5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 747413-08-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-15984. | |
| Veralipride | Veralipride is a D2 receptor antagonist. It is an alternative antidopaminergic treatment for menopausal symptoms. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Veralipride; LIR166. CAS No. 66644-81-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101797. | |
| Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Verapamil; CP-16533-1. CAS No. 52-53-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14275. | |
| Verapamil hydrochloride | Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil hydrochloride also inhibits CYP3A4. Verapamil hydrochloride has the potential for high blood pressure, heart arrhythmias and angina research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Verapamil hydrochloride; CP-16533-1 hydrochloride. CAS No. 152-11-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-A0064. | |
| Veratraldehyde | Veratraldehyde is an important chemical used in perfumery, agrochemical, and pharmaceutical industries. Uses: Scientific research. Group: Natural products. CAS No. 120-14-9. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N1096. | |
| Veratramine | Veratramine(NSC17821; NSC23880) is useful as a signal transduction inhibitor for treating tumors. Uses: Scientific research. Group: Natural products. Alternative Names: NSC17821; NSC23880. CAS No. 60-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0837. | |
| Veratric acid | Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant [1] and anti-inflammatory activities [3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling [2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 3,4-Dimethoxybenzoic acid. CAS No. 93-07-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-N2007. | |
| Veratric acid (Standard) | Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant [1] and anti-inflammatory activities [3]. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling [2]. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation [3]. Uses: Scientific research. Group: Natural products. CAS No. 93-07-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2007R. | |
| Veratridine | Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels ( VGSCs ) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC 50 of 18.39?μM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Veratroylveracevine. CAS No. 71-62-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6691. | |
| Veratrole | Veratrole is a key compound found widely in plants that attracts pollinators. Veratrole can be used as a safe fragrance ingredient with low acute and administration toxicity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 91-16-7. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-B1812. | |
| Verbascoside | Verbascoside is isolated from Acanthus mollis , acts as an ATP-competitive inhibitor of PKC , with an IC 50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity. Uses: Scientific research. Group: Natural products. Alternative Names: Acteoside; Kusaginin; TJC160. CAS No. 61276-17-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0021. | |
| Verbenalin | Verbenalin is Verbena glycoside, with anti-inflammatory, anti-fungal anti-virus activities. Verbenalin can be used for the research of prostatitis. Verbenalin can reduce cerebral ischemia-reperfusion injury [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 548-37-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2014. | |
| Verbenone | Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis [1]. Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones [2]. Uses: Scientific research. Group: Natural products. Alternative Names: (-)-Verbenone. CAS No. 1196-01-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N6661. | |
| Vercirnon | Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 ?M for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1605786; CCX282-B; Traficet-EN. CAS No. 698394-73-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15724. | |
| Verdinexor | Verdinexor(KPT-335) is a novel, orally bioavailable selective inhibitor of nuclear export (SINE), inhibits nuclear export protein Exportin 1(XPO1/CRM1) against canine tumor cell lines; also reduce influenza virus replication in vitro and in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-335. CAS No. 1392136-43-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15970. | |
| Verdiperstat | Verdiperstat (AZD3241) is a selective, irreversible and orally active myeloperoxidase (MPO) inhibitor, with an IC 50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD3241. CAS No. 890655-80-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17646. | |
| Verekitug | Verekitug is an anti- CRLF2 human IgG1 κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2768386-15-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990774. | |
| Vericiguat | Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY1021189. CAS No. 1350653-20-1. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16774. | |
| Verinurad | Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with an IC 50 of 25 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA3170. CAS No. 1352792-74-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16733. | |
| Vernakalant Hydrochloride | Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na + and atria-preferred K + channel blocker. IC 50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channel wt , Kv1.5 channel I508F , Kv1.5 channel T479A , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RSD1235 hydrochloride. CAS No. 748810-28-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14183. | |
| Verosudil | Verosudil (AR-12286) is a ROCK inhibitor. Verosudil has equal inhibitory activity against ROCK1 and ROCK2 (Ki: 2 nM). Verosudil is less selective for PKA, PKCT, MRCKA, and CAM2A (Ki: 69 nM, 9322 nM, 28 nM, 5855 nM, respectively). Verosudil increases trabecular outflow capacity to reduce intraocular pressure. Verosudil is useful in the study of glaucoma and ocular hypertension[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AR-12286. CAS No. 1414854-42-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-16758. | |
| Verrucarin A | Verrucarin A (Muconomycin A), a Type D macrocyclic mycotoxin derived from the pathogen fungus Myrothecium verrucaria , is an inhibitor of protein synthesis. Verrucarin A inhibits growth of leukemia cell lines and activates caspases and apoptosis and inflammatory signaling in macrophages. Verrucarin A effectively increased the phosphorylation of p38 MAPK and diminished the phosphorylation of ERK/Akt. Verrucarin A caused cell cycle deregulation through the induction of p21 and p53 [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Muconomycin A. CAS No. 3148-9-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-107426. | |
| Verteporfin | Verteporfin (CL 318952) is a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as age-related macular degeneration. Verteporfin is a YAP inhibitor which disrupts YAP-TEAD interactions. Verteporfin induces cell apoptosis [1]. Verteporfinis an autophagy inhibitor that blocks autophagy at an early stage by inhibiting autophagosome formation [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CL 318952. CAS No. 129497-78-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0146. | |
| Verubecestat | Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with K i values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8931. CAS No. 1286770-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16759. | |
| (-)-Vesamicol | (-)-Vesamicol (AH5183) is an inhibitor of acetylcholine transport into synaptic vesicles, with the IC 50 of 75 nM [1]. (-)-Vesamicol can be used for release and recycling of synaptic vesicles study [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AH5183. CAS No. 112709-59-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113995. | |
| Vesatolimod | Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC 50 of 291 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9620. CAS No. 1228585-88-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15601. | |
| Vesencumab | Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MNRP-1685A. CAS No. 1205533-60-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99386. | |
| Vesnarinone | Vesnarinone (OPC-8212) is an orally active phosphodiesterase 3 ( PDE3 ) inhibitor. Vesnarinone can increase in calcium flux and decrease in potassium flux. Vesnarinone shows dose-dependent positive inotropic activity. Vesnarinone can be used in heart failure research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-8212. CAS No. 81840-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15297. | |
| Vestitol | Vestitol is the compound isolated from leaves of Trifolium arvense [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Vestitol. CAS No. 56701-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8744. | |
| VGX-1027 | VGX-1027 is an orally active isoxazole compound that exhibits various immunomodulatory properties. VGX-1027 targets macrophages, reducing the production of the proinflammatory mediators TNF-α, IL-1β, IL-10. VGX-1027 has antidiabetogenic effects by limiting cytokine-mediated immunoinflammatory events [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GIT 27. CAS No. 6501-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15507. | |
| VH032 | VH032 is a VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. VH032 is a VHL/HIF-1? interaction inhibitor with a Kd | |
| VH285-PEG4-C4-Cl | VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and 16-atom-length linker. The connector of linker is Halogen group. VH285-PEG4-C4-Cl incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. VH285-PEG4-C4-Cl is a highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM. VH285-PEG4-C4-Cl is able to induce 90 % degradation of GFP-Halotag at 625 nM. VH285-PEG4-C4-Cl binds to VHL with an IC50 of 0.54 ?M[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HaloPROTAC 3. CAS No. 1799506-07-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111997. | |
| VH-298 | VH-298 is a highly potent inhibitor of the VHL:HIF-? interaction with a Kd value of 80 to 90 nM. VH-298 leads to HIF-? accumulation inside HeLa cells. VH-298 is an E3 ligase Ligand, and can be used for synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097381-85-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100947. | |
| Vialinin A | Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties [1]. Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A (Terrestrin A) can be used for autoimmune diseases and cancer research [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Terrestrin A. CAS No. 858134-23-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103435. | |
| Vibecotamab | Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: XmAb14045. CAS No. 2138442-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99521. | |
| Vibegron | Vibegron (MK-4618) is a potent, highly selective and orally active β 3 -adrenoceptor agonist ( EC 50 =1.1 nM). Vibegron can be used for severe urgency urinary incontinence related to overactive bladder [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4618. CAS No. 1190389-15-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19933. | |
| Vibostolimab | Vibostolimab is an anti-TIGIT ( T cell immunoglobulin and ITIM domain ) monoclonal antibody. Vibostolimab shows antitumor activity, and can be used in non-small cell lung cancer (NSCLC) and melanoma research [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2231305-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99202. | |
| Vicagrel | Vicagrel is a potent, safe and orally active antiplatelet agent, which works by irreversibly inhibiting P2Y12 receptor. Vicagrel can be used for the research of blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314081-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118284. | |
| Vicenin 2 | Vicenin 2, a flavonoid, is an orally active angiotensin-converting enzyme (ACE) inhibitor ( IC 50 of 43.83 μM) [1]. Vicenin 2 has radioprotective, anti-nociceptive effects, anti-glycation anti-inflammatory, antioxidant, anticancer, antiangiogenic properties [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 23666-13-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2165. | |
| Vicine | Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 152-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2093. | |
| Vicriviroc maleate | Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5 , with a K i of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC 90 s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH-417690 maleate; SCH-D maleate. CAS No. 599179-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17377. | |
| Vidarabine | Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses [1] [2]. Vidarabine has IC 50 s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 [2]. Vidarabine also has anti- orthopoxvirus activity [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine. CAS No. 5536-17-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0277. | |
| Vidarabine monohydrate | Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral agent which is active against herpes simplex viruses ( HSV ) and varicella zoster viruses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24356-66-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6666. | |
| Vidarabine phosphate | Vidarabine phosphate (Ara-AMP), an antiviral agent, inhibits chronic HBV infection [1] [2]. Vidarabine phosphate also against herpes simplex and varicella zoster viruses [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ara-AMP; ara-A 5'-monophosphate. CAS No. 29984-33-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0277A. | |
| Vidofludimus | Vidofludimus is an orally active inhibitor for dihydroorotate dehydrogenase (DHODH) and also is a novel modulator for farnesoid X receptor (FXR). Vidofludimus, as an immunomodulatory agent, can be used for the research of autoimmune disorders such as inflammatory bowel disease (IBD). Vidofludimus also can be used for the research of fatty liver by targeting FXR [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4sc-101; SC12267. CAS No. 717824-30-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14908. | |
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