MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Ursodeoxycholic acid sodium | Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium. CAS No. 2898-95-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-13771A. |  |
| Ursolic acid | Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. Uses: Scientific research. Group: Natural products. Alternative Names: Prunol; Urson; Malol. CAS No. 77-52-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-N0140. | |
| Ursolic acid acetate | Ursolic acid acetate (Acetylursolic acid), isolated from the aerial roots of Ficus microcarpa , exhibits cytotoxicity against KB cells with IC 50 of 8.4 μM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Acetylursolic acid; 3-Acetylursolic acid. CAS No. 7372-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N2815. | |
| Ursolic acid (Standard) | Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. Uses: Scientific research. Group: Natural products. CAS No. 77-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0140R. | |
| (+)-Usnic acid | (+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR , and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay , with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus , Enterococcus faecalis , and Enterococcus faecium [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 7562-61-0. Pack Sizes: 1 g; 5 g. Product ID: HY-N0656A. | |
| Usnic acid | Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1 [1]. Uses: Scientific research. Group: Natural products. CAS No. 125-46-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0656. | |
| USP15-IN-1 | USP15-IN-1 is a potent USP15 inhibitor with an IC50 value of 3.76 ?M. USP15-IN-1 can be used for researching anticancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2260826-16-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148046. | |
| USP1-IN-7 | USP1-IN-7 (Compound 3) is an inhibitor for ubiquitin specific peptidase 1 ( USP1 ) and its cofactor UAF1 , with IC 50 ≤50 nM. USP1-IN-7 inhibits proliferation of MDA-MB-436 with IC 50 ≤50 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033480-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161446. | |
| USP25/28 inhibitor AZ1 | USP25/28 inhibitor AZ1 (AZ1) is an orally active, selective, noncompetitive, dual ubiquitin specific protease (USP) 25/28 inhibitor with IC50s of 0.7 ?M and 0.6 ?M, respectively. USP25/28 inhibitor AZ1 attenuates colitis and tumorigenesis in the mice model[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZ1. CAS No. 2165322-94-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117370. | |
| USP28-IN-4 | USP28-IN-4 is a USP28 inhibitor (IC50=0.04 ?M) with high selectivity over USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 shows cytotoxicity against cancer cells, down-regulates the cellular level of c-Myc through ubiquitin-proteasome system. USP28-IN-4 also decreases the ankyrase-1/2 level in vitro. USP28-IN-4 enhance the sensitivity of colorectal cancer cells to Regorafenib (HY-10331)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2931509-15-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149230. | |
| USP5-IN-1 | USP5-IN-1 (compound 64) is a selective competitive inhibitor of USP5 zinc finger ubiquitin binding domain (ZnF-UBD) (KD=2.8 ?M). USP5-IN-1 competitively blocks the binding of ubiquitin to ZnF-UBD, inhibits the catalytic activity of USP5, and thus hinders the hydrolysis of ubiquitin chains. USP5-IN-1 can inhibit USP5 cleavage of Lys48-linked diubiquitin substrates in vitro and is a potential USP5 chemical probe and potential inhibitor of USP5-related cancers. Uses: Scientific research. Group: Signaling pathways. CAS No. 2851040-81-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139979. | |
| USP7-797 | USP7-797 (USP7-IN-7) is an orally available, selective USP7 inhibitor (IC50=0.5 nmol/L) with antitumor activity. USP7-797 reduces the level of MDM2, thereby increasing the stability and activity of p53, leading to cell cycle arrest and apoptosis. USP7-797 has low nanomolar cytotoxicity against p53 mutant cancer cell lines, p53 wild-type hematological tumors, and neuroblastoma cell lines[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: USP7-IN-7. CAS No. 2413944-70-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136910. | |
| USP7-IN-13 | USP7-IN-13 (Compound 101) is a USP7 inhibitor with an IC 50 value of 0.2-1 μM, which can be used for the study of multiple myeloma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305046-93-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160515. | |
| USP7/USP47 inhibitor | USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 ?M and 1.0 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1247825-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13487. | |
| Ustekinumab | Ustekinumab is an anti- IL-12 / IL-23 IgG1κ human monoclonal antibody. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL-12/IL-23, Human Antibody. CAS No. 815610-63-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9909. | |
| UT-155 | UT-155 is a selective and potent androgen receptor (AR) antagonist, with a Ki of 267 nM for UT-155 binding to AR-LBD. Uses: Scientific research. Group: Signaling pathways. CAS No. 2031161-35-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112895. | |
| Utomilumab | Utomilumab (PF 05082566) is a fully human IgG2 agonist monoclonal antibody that selectively binds to 4-1BB/CD137. Utomilumab can be used in the research of tumors such as follicular and other CD20+ non-Hodgkin lymphomas[1][2][3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF 05082566. CAS No. 1417318-27-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99056. | |
| Utreglutide | Utreglutide is a potent glucagon-like peptide 1 (GLP-1) receptor agonit [1]. Uses: Scientific research. Group: Peptides. CAS No. 2460862-12-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3388. | |
| Utreloxastat | Utreloxastat (PTC857) is an orally active 15-lipoxygenase inhibitor that can cross the blood-brain barrier. Utreloxastat is a weak inhibitor of CYP1A2 and 2B6 with an IC 50 > 5.3 μM. Utreloxastat reduces oxidative stress and inhibits the consumption of reduced glutathione and ferroptosis. Utreloxastat can be used in the study of neurodegenerative diseases characterized by high levels of oxidative stress and mitochondrial pathology, such as amyotrophic lateral sclerosisc [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PTC857. CAS No. 1213269-96-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132845. | |
| UU | UU ((3,5)-Uridylyluridine) is a nucleobase-containing dinucleotide derivative. UU can be used for the study of RNA-related processes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3,5)-Uridylyluridine. CAS No. 2415-43-2. Pack Sizes: 1 mg. Product ID: HY-159806. | |
| Uvaol | Uvaol, a triterpene present in olives and virgin olive oil, possesses anti-inflammatory properties and antioxidant effects. Uvaol is an orally active inducer of apoptosis in astroglioma cells. Uvaol also has anti-cancer activities. Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 545-46-0. Pack Sizes: 5 mg. Product ID: HY-N1109. | |
| UVI 3003 | UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXR? in Cos7 cells, with IC50s of 0.22 and 0.24 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 847239-17-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107500. | |
| UZH1a | UZH1a is a potent and selective METTL3 inhibitor, with an IC50 of 280 nM. UZH1a can be used for epitranscriptomic modulation of cellular processes. UZH1a has antitumor activity. UZH1a also can be used as a chemical probe for studying METTL3[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2813577-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134673A. | |
| UZH2 | UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2756566-45-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115717. | |
| V-0219 | V-0219 (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 can be used for obesity-associated diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 878453-71-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-143312. | |
| V-0219 hydrochloride | V-0219 hydrochloride (Compound 9) is an orally active, positive allosteric modulator (PAM) of the glucagon-like peptide-1 receptor (GLP-1R). V-0219 hydrochloride can be used for obesity-associated diabetes research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922283-73-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143312A. | |
| V5 Epitope Tag Peptide TFA | V5 Epitope Tag Peptide (TFA) is a tag peptide derived from a small epitope present on the P and V proteins of the paramyxovirus of simian virus 5. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0325. | |
| V-9302 | V-9302 is a competitive antagonist of transmembrane glutamine flux. V-9302 selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 inhibits ASCT2-mediated glutamine uptake ( IC 50 =9.6 μM) in HEK-293 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1855871-76-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112683. | |
| V-9302 hydrochloride | V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake ( IC 50 =9.6 μM) in HEK-293 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2416138-42-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112683A. | |
| VA012 | VA012 (compound 11) is a positive allosteric modulator (PAM) of the serotonin 5-HT 2C receptor. VA012 reduces food intake and body weight gain without causing CNS-related malaise during subchronic administration. VA012 can be utilized in obesity research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 885898-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124821. | |
| Vabicaserin hydrochloride | Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C ( 5-HT 2C ) receptor -selective agonist with an EC 50 of 8 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCA 136. CAS No. 887258-94-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111200. | |
| Vaborbactam | Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophore β-lactamase inhibitor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RPX7009. CAS No. 1360457-46-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19930. | |
| Vactosertib | Vactosertib (EW-7197) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC 50 of 12.9 nM. Vactosertib also inhibits ALK2 and ALK4 ( IC 50 of 17.3 nM) at nanomolar concentrations. Vactosertib has potently antimetastatic activity and anticancer effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EW-7197; TEW-7197. CAS No. 1352608-82-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19928. | |
| Vactosertib Hydrochloride | Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC 50 of 12.9 nM. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 ( IC 50 of 17.3 nM) at nanomolar concentrations. Vactosertib Hydrochloride has potently antimetastatic activity and anticancer effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EW-7197 Hydrochloride; TEW-7197 Hydrochloride. CAS No. 1352610-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19928A. | |
| Vacuolin-1 | Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca2+-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin?1 is a potent and selective PIKfyve inhibitor and inhibits late?stage autophagy by impairing lysosomal maturation. Vacuolin-1 can induce vacuole formation and increase the percentage of enucleated cells[1][2][4].. Uses: Scientific research. Group: Signaling pathways. CAS No. 351986-85-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-118630. | |
| Vadadustat | Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase ( HIF-PH ) inhibitor [1]. Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PG-1016548; AKB-6548. CAS No. 1000025-07-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101277. | |
| Vadastuximab | Vadastuximab is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human CD33 Recombinant Antibody. CAS No. 1436390-64-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99329. | |
| Vadimezan | Vadimezan (DMXAA; ASA-404), the tumor vascular disrupting agent (tumor-VDA), is a murine agonist of the stimulator of interferon genes ( STING ) and also a potent inducer of type I IFNs and other cytokines. Vadimezan has anti-influenza virus H1N1-PR8 activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DMXAA; ASA-404. CAS No. 117570-53-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-10964. | |
| Vafidemstat | Vafidemstat (ORY-2001) is an oral, brain penetrant, dual lysine-specific histone demethylase ( LSD1 )/ MAO-B inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORY-2001. CAS No. 1357362-02-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112623. | |
| VAL-083 | VAL-083 is an alkylating agent that creates N7 methylation on DNA, with antitumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dianhydrodulcitol; Dianhydrogalactitol. CAS No. 23261-20-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16513. | |
| Valacyclovir hydrochloride | Valacyclovir hydrochloride (Valaciclovir hydrochloride) is an orally active antiviral agent for herpes simplex, herpes zoster, and herpes B. Valacyclovir hydrochloride inhibits HSV-1 W ( 50 =2.9 μg/ml). Valacyclovir hydrochloride is a proagent of Aciclovir (HY-17422) [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: Valaciclovir hydrochloride. CAS No. 124832-27-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-17425A. | |
| Val-Ala-PAB | Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1343476-44-7. Pack Sizes: 50 mg; 100 mg. Product ID: HY-125933. | |
| Val-Ala-PAB-MMAE | Val-Ala-PAB-MMAE is a Drug-Linker Conjugate for ADC, consisting of ADC linker (Val-Ala-PAB) and MMAE. MMAE is an effective inhibitor of tubulin. Uses: Scientific research. Group: Signaling pathways. CAS No. 1912408-92-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153032. | |
| Valbenazine | Valbenazine (NBI-98854) is a vesicular monoamine transporter 2 ( VMAT2 ) inhibitor with the K i of 110-190 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-98854. CAS No. 1025504-45-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16771. | |
| Val-Cit-PAB-MMAE | Val-Cit-PAB-MMAE is a agent-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE (HY-15162). MMAE a potent mitotic inhibitor by inhibiting tubulin polymerization. Uses: Scientific research. Group: Signaling pathways. CAS No. 644981-35-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100374. | |
| Val-cit-PAB-OH | Val-cit-PAB-OH is a degradable ADC linker. Uses: Scientific research. Group: Signaling pathways. CAS No. 159857-79-1. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g; 25 g. Product ID: HY-12362. | |
| Valdecoxib | Valdecoxib is a highly potent and selective inhibitor of COX-2 , with IC 50 s of 5 nM and 140 μM for COX-2 and COX-1, respeceively. Valdecoxib can be used in the research of arthritis and pain. Uses: Scientific research. Group: Natural products. Alternative Names: SC 65872. CAS No. 181695-72-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15762. | |
| Valemetostat | Valemetostat (DS-3201), a first-in-class EZH1/2 dual inhibitor with IC 50 values ?10 nM. Valemetostat can be used for the research of relapsed/refractory peripheral T-cell lymphoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS-3201. CAS No. 1809336-39-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-109108. | |
| Valemetostat tosylate | Valemetostat (DS-3201) tosylate, a first-in-class EZH1/2 dual inhibitor with IC 50 values ?10 nM. Valemetostat tosylate can be used for the research of relapsed/refractory peripheral T-cell lymphoma [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DS-3201 tosylate. CAS No. 1809336-93-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109108A. | |
| Valencene | Valencene is a sesquiterpene isolated from Cyperus rotundus , possesses antiallergic, antimelanogenesis, anti-infammatory, and antioxidant activitivies. Valencene inhibits the exaggerated expression of Th2 chemokines and proinflammatory chemokines through blockade of the NF-κB pathway. Valencene is used to flavor foods and drinks [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 4630-7-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6636. | |
| Valepotriate | Valepotriate can be isolated from Valeriana jatamansi Jones, has anti-epileptic and anti-cancer activities [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Valtrate. CAS No. 18296-44-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0718. | |
| Valerate sodium | Valerate (sodium) is an ester product. Uses: Scientific research. Group: Signaling pathways. CAS No. 6106-41-8. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-W007087. | |
| Valerenic acid | Valerenic acid ((-)-Valerenic Acid), a sesquiterpenoid, is an orally active positive allosteric modulator of GABA A receptors. Valerenic acid is also a partial agonist of the 5-HT 5a receptor. Valerenic acid mediates anxiolytic activity via GABA A receptors containing the β3 subunit. Valerenic acid also exhibits potent antioxidant properties [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Valerenic Acid. CAS No. 3569-10-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103524. | |
| Valerylcarnitine | Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines. Uses: Scientific research. Group: Natural products. CAS No. 40225-14-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113266. | |
| Valeryl salicylate | Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Valeroyl salicylate. CAS No. 64206-54-8. Pack Sizes: 10 mg. Product ID: HY-128473. | |
| Valethamate bromide | Valethamate bromide is an ester and is a potent rapidly acting anticholinergic spasmolytic and musculotropic agent which accelerates labor by improving cervical dilation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90-22-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B2112. | |
| Valganciclovir hydrochloride | Valganciclovir hydrochloride is an orally active antiviral agent. Valganciclovir hydrochloride can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir hydrochloride can be used for the research of Cytomegalovirus [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 175865-59-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0032A. | |
| Validamycin A | Validamycin A, a fungicidal, is an agricultural antibiotic. Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus. Validamycin A inhibits the growth of A. flavus , with a MIC of 1?μg/mL [1]. Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani , with an IC 50 of 72 μM [2]. Validamycin A is a reversible tyrosinase inhibitor, with a K i of 5.893 mM [3]. Uses: Scientific research. Group: Natural products. CAS No. 37248-47-8. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B0856. | |
| Valiltramiprosate | ALZ-801 is a potent and orally available small-molecule β-amyloid (Aβ) anti-oligomer and aggregation inhibitor, valine-conjugated proagent of Tramiprosate with substantially improved PK properties and gastrointestinal tolerability compared with the parent compound [1]. ALZ-801 is an advanced and markedly improved candidate for the treatment of alzheimers disease [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALZ-801. CAS No. 1034190-08-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117259. | |
| Valinomycin | Valinomycin is a potassium-specific ionophore, the valinomycin-K + complex can be incorporated into biological bilayer membranes with the hydrophobic surface of valinomycin, destroys the normal K + gradient across the membrane, and as a result kills the cells, incorporating into liposomes can significantly reduces the cytotoxicity and enhances the targeting effect. Valinomycin exhibits antibiotic , antifungal, antiviral, antitumor and insecticidal efficacy, thus can be used for relevant research [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: NSC 122023. CAS No. 2001-95-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6693. | |
| Valnemulin hydrochloride | Valnemulin hydrochloride is an orally effective truncated pleurotin antibiotic that inhibits protein synthesis in bacteria by binding to peptidyl transferase in the 50s ribosome subunit. Valnemulin hydrochloride effectively eliminates Mycobacterium bovis in the lungs in an experimental bovine model of Mycoplasma bovis infection. Valnemulin hydrochloride can reduce the mortality of epidemic rabbit enteropathy and has no adverse effect on the growth performance of rabbits [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133868-46-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0027. | |
| Valnoctamide | Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABA A receptors [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Valmethamide. CAS No. 4171-13-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121877. | |
| Valopicitabine dihydrochloride | Valopicitabine (NM283) dihydrochloride is a nucleoside analog and the orally bioavailable proagent of the potent anti-HCV agent 2'-C-methylcytidine (NM107). NM107competitively inhibits NS5B polymerase, causing chain termination [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NM283 dihydrochloride. CAS No. 640725-71-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108060A. | |
| Valproic acid | Valproic acid (VPA) is an orally active HDAC inhibitor, with IC 50 in the range of 0.5 and 2 mM. Valproic acid inhibits HDAC1 ( IC 50 , 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid is used in the epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: Dipropylacetic Acid. CAS No. 99-66-1. Pack Sizes: 500 mg; 1 g; 5 g; 25 g. Product ID: HY-10585. | |
| Valproic acid-d4 | Valproic acid-d 4 is the deuterium labeled Valproic acid. Valproic acid (VPA; 2-Propylpentanoic Acid) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: VPA-d4; 2-Propylpentanoic Acid-d4. CAS No. 87745-17-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-10585S. | |
| Valproic acid sodium | Valproic acid (Sodium Valproate) sodium is an orally active HDAC inhibitor, with IC 50 in the range of 0.5 and 2 mM, also inhibits HDAC1 ( IC 50 , 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium is used in the treatment of epilepsy, bipolar disorder, metabolic disease, HIV infection and prevention of migraine headaches [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Natural products. Alternative Names: Sodium Valproate sodium. CAS No. 1069-66-5. Pack Sizes: 500 mg; 1 g; 5 g; 25 g. Product ID: HY-10585A. | |
| Valproic acid (Standard) | Valproic acid (Dipropylacetic Acid) (Standard) is an analytical standard for valproic acid. This product is intended for research and analytical applications. Valproic acid is an orally active HDAC inhibitor ( IC 50 =0.5-2 mM), inhibits the activity of HDAC1 ( IC 50 =400 μM), and induces the degradation of HDAC2. Valproic acid activates Notch1 signaling and inhibits the proliferation of small cell lung cancer (SCLC) cells. Valproic acid is used in the study of epilepsy, bipolar disorder, metabolic diseases, HIV infection, and migraine [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dipropylacetic Acid (Standard). CAS No. 99-66-1. Pack Sizes: 100 mg; 250 mg; 500 mg. Product ID: HY-10585R. | |
| Valpromide | Valpromide is an amide derivative of valproic acid and inhibits human epoxide hydrolase. Uses: Scientific research. Group: Signaling pathways. CAS No. 2430-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B2117. | |
| Valrocemide | Valrocemide (TV1901) is a promising antiepileptic agent candidate that shows a broad spectrum of anticonvulsant activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TV1901. CAS No. 92262-58-3. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100379. | |
| Valrubicin | Valrubicin is a chemotherapy agent, inhibits TPA- and PDBu-induced PKC activation with IC 50 s of 0.85 and 1.25 μM, respectively, and has antitumor and antiinflammatory activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AD-32. CAS No. 56124-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13772. | |
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