MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| Tulathromycin A | Tulathromycin A (Tulathromycin), a macrolide antibiotic , inhibits protein synthesis (IC 50 =0.26 μM) by targeting bacterial ribosome. Tulathromycin A is used for the research of respiratory disease in cattle and swine. Immunomodulatory effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tulathromycin; CP 472295. CAS No. 217500-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15662. |  |
| Tulisokibart | Tulisokibart (PRA023) is a humanized IgG1-κ monoclonal antibody. Tulisokibart targets to TNFSF15 /TL1A. Tulisokibart can be used to study a variety of inflammatory/fibrotic diseases, such as Crohn's Disease (CD) and ulcerative colitis [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRA023; PRA-023. CAS No. 2648504-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990007. | |
| Tulmimetostat | Tulmimetostat (CPI-0209) is an orally active EZH1/EZH2 inhibitor that targets and inhibits the EZH2 enzyme.Tulmimetostat has antitumor activity and is used in a variety of solid tumor studies[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPI-0209. CAS No. 2567686-02-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145602. | |
| Tulobuterol | Tulobuterol (C-78 free base) is a long-acting β 2 -adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol is also a sympathomimetic agent used as a transdermal patch, and increases normal diaphragm muscle strength [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C-78 free base. CAS No. 41570-61-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B1810. | |
| Tulobuterol hydrochloride | Tulobuterol hydrochloride (C-78) is a long-acting β 2 -adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength [1]. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C-78. CAS No. 56776-01-3. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-W011733. | |
| Tunicamycin | Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity[1][2][3].Tunicamycin increases exosome release in cervical cancer cells[4]. Uses: Scientific research. Group: Natural products. CAS No. 11089-65-9. Pack Sizes: 2 mg; 5 mg; 10 mg. Product ID: HY-A0098. | |
| Tunlametinib | Tunlametinib, an antineoplastic agent, is a MEK1/2 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HL-085. CAS No. 1801756-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132844. | |
| Turanose | Turanose is an isomer of Sucrose that naturally exists in honey. Turanose has anti-inflammatory and regulates adipogenesis effect. Turanose has potential for obesity and related chronic diseases research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 547-25-1. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113334. | |
| Turkesterone | Turkesterone is a potent ecdysteroid. Turkesterone acts as an ecdysteroid receptor ( EcR ) agonist in some insect systems [1]. Uses: Scientific research. Group: Natural products. CAS No. 41451-87-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2548. | |
| Turofexorate isopropyl | Turofexorate isopropyl (FXR-450) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FXR-450; XL335; WAY-362450. CAS No. 629664-81-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50911. | |
| Tusamitamab | Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative) [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2349294-95-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99054. | |
| Tusamitamab ravtansine | Tusamitamab ravtansine (SAR-408701) is a targeted ADC against tumor cells expressing CEACAM5 , composed of a humanized anti-CEACAM5 monoclonal antibody covalently linked to the potent cytotoxic agent, maytansinoid DM4 (HY-12454), via a cleavable linker. Tusamitamab ravtansine has an average drug-to-antibody ratio (DAR) of 3.8 [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: SAR-408701; HuMAb2-3-SPDB-DM4. CAS No. 2254086-60-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99542. | |
| Tuspetinib | Tuspetinib (HM43239) is an orally active and selective FLT3 inhibitor with IC 50 s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib inhibits the proliferation and induces the apoptosis of leukemic cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HM43239. CAS No. 2294874-49-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145015. | |
| Tuvusertib | Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a K i value below 1 μΜ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: M1774; ATR inhibitor 1. CAS No. 1613200-51-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111451. | |
| TVB-3166 | TVB-3166 is an orally-available, reversible, and selective fatty acid synthase (FASN) inhibitor with IC50s of 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis, respectively. TVB-3166 induces apoptosis, and inhibits in-vivo xenograft tumor growth[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1533438-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120394. | |
| TVB-3664 | TVB-3664 is an orally available, reversible, potent, selective and highly bioavailable fatty acid synthase (FASN) inhibitor, with IC50 values of 18 nM and 12 nM for human and mouse cell palmitate synthesis, respectively. TVB-3664 significantly reduces tubulin palmitoylation and mRNA expression[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097262-58-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120062. | |
| TW-37 | TW-37 is a potent Bcl-2 inhibitor with K i values of 260, 290 and 1110 nM for Mcl-1 , Bcl-2 and Bcl-xL , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 877877-35-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12020. | |
| Tween 20 | Tween 20 (Polysorbate 20) is a polyoxyethylene (POE)-type nonionic surfactant [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polysorbate 20. CAS No. 9005-64-5. Pack Sizes: 100 mL. Product ID: HY-141415. | |
| Tween 80 | Tween 80 (Polysorbate 80), a surfactant, has been widely used as a solvent for pharmacological experiments. Tween 80 can also reduce bacterial attachment and inhibit biofilm formation. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Polysorbate 80. CAS No. 9005-65-6. Pack Sizes: 50 mL; 100 mL. Product ID: HY-Y1891. | |
| TWS119 | TWS119 is an inhibitor of GSK-3β , with an IC 50 of 30 nM, and activates the wnt/β-catenin pathway. Uses: Scientific research. Group: Signaling pathways. CAS No. 601514-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10590. | |
| TX1-85-1 | TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1603845-32-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-100848. | |
| TXA707 | TXA707, the active metabolite of TXA-709, is an FtsZ inhibitor with antibacterial activity. TXA707 is promising for research of S. aureus infections [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1609670-89-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153695. | |
| TY-52156 | TY-52156 is a potent and selective S1P3 receptor antagonist with a Ki value of 110 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 934369-14-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19736. | |
| TYA-018 | TYA-018 is an orally active, potent and highly selective HDAC6 inhibitor. TYA-018 can protect heart function in mice. TYA-018 also enhances energetics in mice by increasing expression of targets associated with fatty acid metabolism, protein metabolism, and oxidative phosphorylation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2653254-31-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153392. | |
| Tyk2-IN-19 | Tyk2-IN-19 (compound 1) is an orally active and blood-brain barrier (BBB) permeable Tyk2 inhibitor. Tyk2-IN-19 can be used for study of neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2866415-98-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161683. | |
| Tylosin | Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1401-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0519A. | |
| Tylosin phosphate | Tylosin phosphate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin phosphate is widely used as a feed additive for promoting animal growth. Tylosin phosphate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 1405-53-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0519B. | |
| Tylosin tartrate | Tylosin tartrate is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin tartrate exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin tartrate is widely used as a feed additive for promoting animal growth. Tylosin tartrate is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 74610-55-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0519. | |
| Tyloxapol | Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 25301-02-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-B1068. | |
| Tylvalosin | Tylvalosin (Acetylisovaleryltylo sin) is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin is an antiviral agent used to study PRRSV infection. Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, alleviates oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylisovaleryltylo?sin. CAS No. 63409-12-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-128423A. | |
| Tylvalosin tartrate | Tylvalosin (Acetylisovaleryltylosin) tartrate is an orally active, broad-spectrum macrolide antibiotic with antimicrobial activity. Tylvalosin tartrate is an antiviral agent useful in studying PRRSV infection. Tylvalosin tartrate induces apoptosis. Tylvalosin tartrate also has anti-inflammatory activity, relieves oxidative stress, and alleviates acute lung injury by inhibiting NF-κB activation [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Acetylisovaleryltylo?sin tartrate. CAS No. 63428-13-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-128423. | |
| [Tyr8]-Substance P | [Tyr8]-Substance P is an active peptide. [Tyr8]-Substance P can be used for the research of various biochemical [1]. Uses: Scientific research. Group: Peptides. CAS No. 55614-10-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2784. | |
| TYRA-300 | TYRA-300 is an orally active, selective inhibitor for FGFR3 with an IC 50 of 11 nM in Ba/F3. TYRA-300 exhibits antitumor efficacy against urothelial cancers and solid tumors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2800223-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159642. | |
| Tyramide Amplification Buffer | Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products[1]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 2 mL; 20 mL. Product ID: HY-D1840. | |
| Tyramine | Tyramine is an amino acid that helps regulate blood pressure. Tyramine occurs naturally in the body, and it's found in certain foods [1]. Uses: Scientific research. Group: Natural products. CAS No. 51-67-2. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-W007606. | |
| Tyramine hydrochloride | Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods [1]. Uses: Scientific research. Group: Natural products. CAS No. 60-19-5. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg. Product ID: HY-W016823. | |
| Tyr-Gly-Gly-Phe-Met-OH | Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor. Uses: Scientific research. Group: Peptides. Alternative Names: Met-Enkephalin; Methionine enkephalin; Metenkefalin. CAS No. 58569-55-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0073. | |
| Tyrosinase-IN-12 | Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC 50 value of 49.33 ± 2.64 μM and K i value of 31.25 ± 0.25 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species ( ROS ) with an IC 50 value of 25.39 ± 0.77 μM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1860779-42-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-149404. | |
| Tyrosinase, Mushroom | Tyrosinase (EC 1.14.18.1) (Polyphenol oxidase) is a rate-limiting enzyme that controls the production of melanin and is encoded by TYR gene. Tyrosinase is mainly found in melanosomes synthesized by skin melanocytes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Polyphenol oxidase. CAS No. 9002-10-2. Pack Sizes: 1 KU; 5 KU. Product ID: HY-125860. | |
| Tyrosine decarboxylase, Microorganism | Tyrosine decarboxylase, Microorganism (TDC) widely exists in plants, insects and different microorganisms, and is often used in biochemical research. Tyrosine decarboxylase is a pyridoxal 5'-phosphate (PLP)-dependent decarboxylase that catalyzes the removal of carboxyl groups from tyrosine to produce tyramine and carbon dioxide [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TDC; TyrDC. CAS No. 9002-9-9. Pack Sizes: 25 U. Product ID: HY-P2825. | |
| Tyrosine kinase-IN-7 | Tyrosine kinase-IN-7 (compound 13h) is an inhibitor of the tyrosine kinase EGFR. The IC 50 s for inhibiting EGFR(WT) and EGFR(T790M) are 0.630 μM and 0.956 μM respectively. Tyrosine kinase-IN-7 has antitumor activity against four cancer cell lines (HepG2, HCT-116, MCF-7, and A431) with IC 50 s of 13.02 μM, 10.14 μM, 12.68 μM, and 47.05 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 345615-74-9. Pack Sizes: 10 mg. Product ID: HY-156912. | |
| Tyrosine kinase inhibitor | Tyrosine kinase inhibitor is a potent tyrosine kinase inhibitor. Uses: Scientific research. Group: Signaling pathways. CAS No. 1021950-26-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10421. | |
| Tyrosol | Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 501-94-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-N0474. | |
| Tyrosol (Standard) | Tyrosol (Standard) is the analytical standard of Tyrosol. This product is intended for research and analytical applications. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 501-94-0. Pack Sizes: 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-N0474R. | |
| Tyrosylleucine | Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Tyr-Leu. CAS No. 17355-10-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122794. | |
| Tyrosylleucine TFA | Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Tyr-Leu TFA. CAS No. 66852-01-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122794A. | |
| Tyrothricin | Tyrothricin is a polypeptide antibiotic mixture isolated from Bacillus brevis and consists of tyrocidines and gramicidins. Tyrothricin shows activity against bacteria , fungi and some viruses. Tyrothricin containing formulations are used in sore throat agents and in agents for the healing of infected superficial and small-area wounds [1]. Uses: Scientific research. Group: Natural products. CAS No. 1404-88-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120435. | |
| Tyrphostin A51 | Tyrphostin A51 is a potent protein tyrosine kinase (PTK) inhibitor. Tyrphostin A51 inhibits the volume-dependent release of [ 3 H]taurine in a dose-dependent manner. Tyrphostin A51 markedly reduces cellular tyrosyl phosphorylation level. Tyrphostin A51 inhibits both basal and EGF-induced human bone cell proliferation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-183. CAS No. 126433-07-6. Pack Sizes: 1 mg. Product ID: HY-101960A. | |
| Tyrphostin A9 | Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has anti-influenza virus activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrphostin 9; Malonoben. CAS No. 10537-47-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15511. | |
| Tyrphostin AG1296 | Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 ?M. Tyrphostin AG1296 inhibits signaling of human PDGF ?- and ?-receptors as well as of the related stem cell factor receptor (c-Kit). Tyrphostin AG1296 is also a potent inhibitor of FLT3, with an IC50 in the micromolar range[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG1296. CAS No. 146535-11-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13894. | |
| Tyrphostin AG 879 | Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation ( IC 50 of 10 μM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC 50 of 1 μM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG 879. CAS No. 148741-30-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-20878. | |
| Tz-Thalidomide | Tz-Thalidomide is a tetrazine tagged Thalidomide (HY-14658) (Ligands for E3 Ligase). Tz-Thalidomide has binding affinity for BRD4, with IC50s of 46.25 ?M (BRD4-1) and 62.55 ?M (BRD4-2). Tz-Thalidomide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2087490-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101460. | |
| U0124 | U0124, an inactive U0126 analog, has no effect on c-Fos and c-Jun protein or mRNA levels. U0126 is a MEK inhibitor. U0124 does not inhibit MEK at concentrations up to 100 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 108923-79-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107621. | |
| U0126 | U0126 is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC 50 s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 109511-58-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12031A. | |
| U0126-EtOH | U0126 (U0126-EtOH) is a potent, non-ATP competitive and selective MEK1 and MEK2 inhibitor, with IC50s of 72 nM and 58 nM, respectively. U0126 is an autophagy and mitophagy inhibitor[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1173097-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12031. | |
| U-104 | U-104 (SLC-0111) is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with Ki values of 45.1 nM and 4.5 nM, respectively. U-104 shows a significant delay in tumor growth in mice model[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SLC-0111. CAS No. 178606-66-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13513. | |
| U18666A | U18666A, an intra-cellular cholesterol transport inhibitor, inhibits replication of Ebola virus, dengue virus, and human hepatitis C virus[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3039-71-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107433. | |
| U3-1784 | U3-1784 is a humanized antibody expressed in CHO that targets FGFR4/CD334. U3-1784 is equipped with a huIgG1 heavy chain and a hu? light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for U3-1784 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Group: Inhibitory antibodies. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990672. | |
| U-46619 | U-46619 (9,11-Methanoepoxy PGH2) is a stable analogue of Thromboxane A2 (HY-113350) (TXA2) and acts as a potent TXA2 (TP) agonist. U-46619 also is a RhoA agonist. U-46619 stimulates the activation of RhoA through TXA2 receptor activation [1] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 9,11-Methanoepoxy PGH2. CAS No. 56985-40-1. Pack Sizes: 1 mg (28.5 mM * 100 μL in Methyl acetate); 5 mg (28.5 mM * 500 μL in Methyl acetate). Product ID: HY-108566. | |
| (-)-U-50488 hydrochloride | (-)-U-50488 hydrochloride ((-)-Trans-(1S,2S)-U-50488 hydrochloride) is a selective kappa-opioid receptor (KOR) agonist (b>K d=2.2 nM) over μ-opioid receptor (MOR) (b>K d =430 nM). (-)-U-50488 hydrochloride is a more active enantiomer than (+) trans-(1R,2R) U-50488 (HY-15997A) or the (±) trans-racemic mixture U-50488 (HY-15997B). (-)-U-50488 hydrochloride has a potent and sustained anti- HIV effect in fected blood monocyte-derived macrophages (MDM) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (-)-Trans-(1S,2S)-U-50488 hydrochloride. CAS No. 114528-79-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15997. | |
| (±)-U-50488 hydrochloride | (±)-U-50488 ((±)-Trans-(1R,2R)-U-50488) hydrochloride is a selective κ opioid receptor (KOR) agonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Trans-(1R,2R)-U-50488 hydrochloride. CAS No. 67197-96-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15997B. | |
| U-69593 | U-69593 is a potent and selective κ1-opioid receptor agonist [1]. U-69593 attenuates addictive agent-induced behavioral sensitization in the rat [2]. U-69593 reduces anxiety and enhances spontaneous alternation memory in mice [3]. U-69593 reduces calcium-dependent dialysate levels of dopamine and glutamate in the ventral striatum [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 96744-75-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-12363. | |
| U-73122 | U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC 50 of 1-2.1 μM for PLC. Uses: Scientific research. Group: Signaling pathways. CAS No. 112648-68-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13419. | |
| U-73343 | U-73343, works as a protonophore, is an inactive analog of U-73122 and can be used as a negative control. U-73343 dose-dependently inhibits acid secretion irrespective of the stimulant. U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC 50 of 1-2.1 μM for PLC [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 142878-12-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-108630. | |
| U-74389G | U-74389G (PNU74389G meleate) is an antioxidant , can inhibit lipid peroxidation reactions. U-74389G can protect against ischemia-reperfusion injury and be widely used in animal models of ischemic injury and hypertension. U-74389G shows anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU74389G (meleate). CAS No. 153190-29-5. Pack Sizes: 10 mg; 25 mg. Product ID: HY-106592A. | |
| U-83836E | U-83836E (PNU-83836E) is a compound with anti-inflammatory and antioxidant activities that reduces lung inflammation inhibiting oxidative stress and ROS production. U-83836E has shown potential for treating asthma and lung inflammation in animal models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PNU-83836E. CAS No. 137018-55-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117762. | |
| U-99194 maleate | U-99194 maleate is a potent and selective Dopamine3 Receptor (D3 receptor) antagonist. U-99194 maleate also enhances prolactin secretion and striatal dopamine synthesis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: U-99194A; PNU-99194A maleate; JPC-211 maleate. CAS No. 234757-41-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-12701A. | |
| UAA crosslinker 1 hydrochloride | UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1]. UAA crosslinker 1 (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1994331-17-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-111434A. | |
| UAMC-1110 | UAMC-1110 is a highly potent and selective inhibitor of fibroblast activation protein (FAP) with an IC50 of 3.2 nM. UAMC-1110 also inhibits prolyl oligopeptidase (PREP) with an IC50 of 1.8 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1448440-52-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100684. | |
| UAMC-3203 | UAMC-3203 is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2271358-64-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-112909. | |
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