MedChemExpress MCE - Products
MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use.
| Product | Description | |
|---|---|---|
| BW-723C86 | BW-723C86 is an orally active and a selective 5-HT 2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369. |  |
| BX-320 | BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC 50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702676-93-5. Pack Sizes: 1 mg. Product ID: HY-10515. | |
| BYK 191023 dihydrochloride | BYK 191023 is a highly selective inducible nitric-oxide synthase (iNOS) inhibitor. BYK 191023 interacts with the catalytic center of the enzyme. BYK 191023 can be used to study the in vivo and in vitro effects mediated by iNOS [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1216722-25-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107584. | |
| Bz 423 | Bz 423 is a pro-apoptotic 1,4-benzodiazepine with therapeutic properties in murine models of lupus demonstrating selectivity for autoreactive lymphocytes, and activates Bax and Bak. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BZ48. CAS No. 216691-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13108. | |
| Bz-FVR-AMC | Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a k cat /K m value of 1070 mM -1 s -1. The high concentration of BZ-FVR-AMC inhibits the substrate [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 88899-22-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1634. | |
| Bz-rA | Bz-rA (N6-Benzoyladenosine) is a N6-protected adenosine that can be used to synthesize oligoribonucleotides [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N6-Benzoyladenosine. CAS No. 4546-55-8. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g; 100 g. Product ID: HY-W008388. | |
| C10 Bisphosphonate | C10 Bisphosphonate is an inhibitor for acid sphingomyelinase. C10 Bisphosphonate is promising for research of inflammatory lung diseases, cystic fibrosis and atherosclerosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15049-93-1. Pack Sizes: 1 mg. Product ID: HY-48917. | |
| C12-200 | C12-200 is a type of ionizable cationic lipid and helper lipid commonly used for mRNA delivery. In the hemophilia B mouse model, mRNA encoding human erythropoietin (EPO) and coagulation factor IX (FIX) can be successfully delivered and expressed using C12-200. C12-200 is utilized in research related to hemophilia B [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 1220890-25-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145405. | |
| C12-Ceramide | C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease [1] [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine. CAS No. 74713-60-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100353. | |
| C14 Ceramide (d18:1/14:0) | C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123408-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124177A. | |
| C16-Ceramide | C16-Ceramide is a natural small molecule activating p53 through the direct and selective binding [1]. Uses: Scientific research. Group: Natural products. CAS No. 24696-26-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100354. | |
| C16 Ceramide-1-phosphate (d18:1/16:0) ammonium | C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium) (C16 Ceramide-1-phosphate (ammonium); Ceramide-1-phosphate (d18:1/16:0) (ammonium)) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C16 Ceramide-1-phosphate ammonium; Ceramide-1-phosphate (d18:1/16:0) ammonium; CerP(d18:1/16:0) ammonium. CAS No. 1246303-22-9. Pack Sizes: 5 mg. Product ID: HY-145467. | |
| C16 PEG2000 Ceramide | C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide. C16 PEG2000 Ceramide can be used for lipid carrier to delivery. C16 PEG2000 Ceramide induces autophagy. C16 PEG2000 Ceramide can be used for cancer research [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: C16 PEG Ceramide (MW 2000). CAS No. 212116-78-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144005. | |
| C18:1-Ceramide | C18:1-Ceramide is a ceramide subspecies. C18:1-Ceramide can be used in the study of type 2 diabetes [1]. Uses: Scientific research. Group: Natural products. CAS No. 5966-28-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141578. | |
| C188 | C188 is a STAT3 inhibitor that inhibits IL-6-stimulated STAT3 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket. C188, in particular, was highly active in inducing apoptosis of the breast cancer cell line MB-MDA-468 in vitro ( EC 50 = 0.7 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: CPD188. CAS No. 823828-18-8. Pack Sizes: 5 mg. Product ID: HY-112338. | |
| C188-9 | C188-9 (TTI-101) is a STAT3 inhibitor, with a K d of 4.7 nM. C188-9 inhibits G-CSF-induced STAT3 activation and STAT3-dependent gene expression. C188-9 induces apoptosis in AML cell lines and primary samples and inhibits colony formation by primary AML blasts [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TTI-101. CAS No. 432001-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112288. | |
| C18-Ceramide | C18-Ceramide is a bioactive molecule with multiple functions in cells, can cross the blood-brain barrier, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2304-81-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100355. | |
| C18-Ceramide-d7 | C18-Ceramide-d 7 is deuterium labeled C18-Ceramide. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1840942-14-4. Pack Sizes: 500 μg (1.75 mM * 500 μL in Methanol:Chloroform (10:90)); 1 mg; 5 mg. Product ID: HY-100355S1. | |
| C18 Dihydroceramide | C18 Dihydroceramide is an ester product. Uses: Scientific research. Group: Signaling pathways. CAS No. 2304-80-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141580. | |
| C20 Ceramide | C20 Ceramide is a natural 20:0 ceramide that is abundant in the brain [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Arachidoyl-D-sphingosine. CAS No. 7344-2-7. Pack Sizes: 1 mg. Product ID: HY-112016. | |
| C215 | C215 is a potent inhibitor of MmpL3. C215 is identified in HTS with glycerol independent activity against M. tuberculosis , limited non-specific toxicity against mammalian cells, an IC 90 of 16 μM against M. tuberculosis , and efficacy against M. tuberculosis growing in macrophages [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 912780-51-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-124814. | |
| C22-Ceramide | C22-Ceramide (Cer d18:1/22:0) is an endogenous bioactive sphingolipid. C22-Ceramide reduces the propensity of C16-ceramide channel formation in isolated rat liver mitochondria and in liposomes [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Behenoyl-D-erythro-sphingosine; Cer d18:1/22:0. CAS No. 27888-44-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154831. | |
| C24:1-Ceramide | C24:1-Ceramide is one of the most abundant naturally occurring ceramide. Ceramides regulates many diverse biological activities, such as cell apoptosis , cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 54164-50-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134575. | |
| C24-Ceramide (d18:1/24:0) | C24-Ceramide (d18:1/24:0) is a sphingolipid that can be used for the lipid membranes composed. C24-Ceramide (d18:1/24:0) induces time-dependent changes in membrane properties. C24-Ceramide (d18:1/24:0) induces membrane reorganization [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 102917-80-6. Pack Sizes: 1 mg. Product ID: HY-134508A. | |
| C24-Ceramide-d7 | C24-Ceramide-d 7 is the deuterium labeled C24-Ceramide[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1840942-15-5. Pack Sizes: 1 mg; 5 mg; 500 μg. Product ID: HY-134508S. | |
| C2 Ceramide | C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation, autophagy and apoptosis , inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ceramide 2. CAS No. 3102-57-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-101180. | |
| C3a (70-77) | C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a, exhibits the specificity and 1 to 2% biologic activities of C3a. Uses: Scientific research. Group: Peptides. Alternative Names: Complement 3a (70-77). CAS No. 63555-63-5. Pack Sizes: 1 mg. Product ID: HY-P1505. | |
| C6 Ceramide | C6 Ceramide (C6-Cer) is a short-chain, cell-permeable ceramide pathway activator with anticancer activity. C6 Ceramide-mediated miR-29b expression participates in the progression of multiple myeloma through suppressing the proliferation, migration and angiogenesis of endothelial cells by targeting Akt signal pathway. C6 Ceramide exhibits multiple anti-cancer properties including cell cycle arrest, Apoptosis , inhibition of tumor growth and enhances the effects of chemotherapy in drug-resistant cancer cells. C6-ceramide can be used as an adjuvant for chemotherapeutic agents, to enhance anti-tumor effects [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C6-Cer; N-Hexanoylsphingosine. CAS No. 124753-97-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19542. | |
| C6 NBD Ceramide | C6 NBD Ceramide is a Golgi apparatus fluorescent probe with cell membrane permeability. C6 NBD Ceramide can be used for fast and convenient green fluorescent labeling of Golgi in living and fixed cells, and can be used to observe changes in Golgi morphology in living cells (Ex=466 nm, Em=536 nm). C6-NBD-ceramide is metabolized to fluorescent sphingomyelin and glucosylceramide, can be used for the study of sphingolipid transport and metabolic mechanism [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Nbd-ceramide. CAS No. 94885-02-6. Pack Sizes: 1 mg. Product ID: HY-W356116. | |
| C6 NBD Sphingomyelin | C6 NBD Sphingomyelin is a fluorescent short-chain analogue of Sphingomyelin (HY-113498). Chlamydia trachomatis acquires C6 NBD Sphingomyelin endogenously synthesizes from C6-NBD-ceramide and transportes to the chlamydial inclusion. C6 NBD Sphingomyelin can incorporate into the plasma membrane [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 94885-04-8. Pack Sizes: 100 μg; 500 μg. Product ID: HY-D1574. | |
| C75 | C75 is a synthetic fatty-acid synthase ( FASN ) inhibitor; inhibits prostate cancer cells PC3 with an IC 50 of 35 μM [1] [2] [3]. C75 is a potent CPT1A activator [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 218137-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12364. | |
| C 87 | C 87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC 50 of 8.73 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 332420-90-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100735. | |
| C8-Ceramide | C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Octanoyl-D-erythro-sphingosine. CAS No. 74713-59-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108391. | |
| C8 PEG750 Ceramide | C8 PEG750 Ceramide is a lipid product. C8 PEG750 Ceramide synthesizes a lipid bilayer carrier for the selective delivery of various diagnostic and therapeutic agents to acidic diseased cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 212116-76-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-144008B. | |
| CA-074 | CA-074 is a potent inhibitor of cathepsin B with a K i of 2 to 5 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 134448-10-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-103350. | |
| CA-074 methyl ester | CA-074 methyl ester is a specific inhibitor of Cathepsin B , which has potent bioactivities such as neuroprotective, anti-cancer, and anti-inflamatory effects. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CA-074Me. CAS No. 147859-80-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100350. | |
| CA224 | CA224 (Compound 1) is a selective and orally active Cdk4 - cyclin D1 inhibitor with an IC 50 of 6.2 μM. CA224 induces cell apoptosis and shows antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 883561-04-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-111207. | |
| Cabamiquine | Cabamiquine (DDD107498) is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDD107498; DDD-498; M5717. CAS No. 1469439-69-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117684. | |
| Cabamiquine succinate | Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC 50 of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII , with an EC 50 of 2 nM for WT- Pf eEF2 [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDD107498 succinate; DDD-498 succinate; M5717 succinate. CAS No. 2444781-71-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117684A. | |
| Cabazitaxel | Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Uses: Scientific research. Group: Natural products. Alternative Names: XRP6258; RPR-116258A; taxoid XRP6258. CAS No. 183133-96-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15459. | |
| Cabergoline | Cabergoline is an ergot derived-dopamine D 2 -like receptor agonist that has high affinity for D 2 , D 3 , and 5-HT 2B receptors ( K i =0.7, 1.5, and 1.2, respectively). Uses: Scientific research. Group: Signaling pathways. Alternative Names: FCE-21336. CAS No. 81409-90-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15296. | |
| Cabiralizumab | Cabiralizumab (FPA 008) is an anti- CSF1R monoclonal antibody (MAb). Cabiralizumab enhances T cell infiltration and antitumor T cell immune responses. Cabiralizumab inhibits the activation of osteoclasts and blocks bone destruction, and can be used in the research of rheumatoid arthritis (RA). Cabiralizumab can combine with Nivolumab (HY-P9903) for lung cancer research [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: FPA 008; Anti-Human CSF1R Recombinant Antibody. CAS No. 1613144-80-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99259. | |
| Cabotegravir | Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744; S/GSK1265744. CAS No. 1051375-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592. | |
| Cabotegravir sodium | Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir sodium can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744 sodium; S/GSK1265744 sodium. CAS No. 1051375-13-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592A. | |
| Cabozantinib | Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET , with IC 50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT , RET , AXL , TIE2 , and FLT3 ( IC 50 =4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL184; BMS-907351. CAS No. 849217-68-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13016. | |
| Cabozantinib S-malate | Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2 , c-Met , Kit , Axl and Flt3 with IC 50 s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL184 S-malate; BMS-907351 S-malate. CAS No. 1140909-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12044. | |
| Cabozantinib (Standard) | Cabozantinib (Standard) is the analytical standard of Cabozantinib. This product is intended for research and analytical applications. Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET , with IC 50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT , RET , AXL , TIE2 , and FLT3 ( IC 50 =4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 849217-68-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13016R. | |
| Cadazolid | Cadazolid (ACT-179811) is a new oxazolidinone antibiotic with potent activity against Clostridium difficile. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-179811. CAS No. 1025097-10-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100436. | |
| Cadonilimab | Cadonilimab (AK104) is a humanized tetravalent IgG1 bispecific antibody targeting PD1/CTLA4. Cadonilimab blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC) [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AK104. CAS No. 2394841-59-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99117. | |
| Cadralazine | Cadralazine (ISF 2469) is an orally active antihypertensive agent. Cadralazine is a peripheral arteriolar vasodilator [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISF 2469. CAS No. 64241-34-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-106538. | |
| Cadrofloxacin | Cadrofloxacin (Caderofloxacin; CS-940), a orally active fluoroquinolone, is effective against aerobic/anaerobic Gram-positive and Gram-negative bacteria. Cadrofloxacin can be used for the research of infectious diseases [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Caderofloxacin; CS-940. CAS No. 153808-85-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116228. | |
| Cafestol | Cafestol is an orally active diterpenoid and an inhibitor of ERK2. Cafestol has elevated blood lipids, anti-inflammatory, anti-angiogenic and anti-diabetic activities. In addition, Cafestol induces tumor cell apoptosis and autophagy , which can be used in the study of cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 469-83-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N6257. | |
| Caffeic acid | Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase ( 5-LO ). Uses: Scientific research. Group: Natural products. CAS No. 331-39-5. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g; 25 g. Product ID: HY-N0172. | |
| Caffeic acid phenethyl ester | Caffeic acid phenethyl ester is a NF-κB inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 104594-70-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 100 mg; 500 mg; 1 g. Product ID: HY-N0274. | |
| Caffeic acid (Standard) | Caffeic acid (Standard) is the analytical standard of Caffeic acid. This product is intended for research and analytical applications. Caffeic acid is an inhibitor of both TRPV1 ion channel and 5-Lipoxygenase (5-LO). Uses: Scientific research. Group: Natural products. CAS No. 331-39-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0172R. | |
| Caffeine orange | Caffeine orange (Compound 1) is an aqueous-phase fluorescence turn-on sensor for caffeine that is highly selective to caffeine. Caffeine orange makes caffeinated coffee appear orange when exposed to 532 nM of green excitation light. Caffeine orange has excellent photophysical properties such as high extinction coefficient, high light stability and narrow emission bandwidth, which can be used in the research of caffeine detection devices [1] ?. Uses: Scientific research. Group: Fluorescent dye. CAS No. 1632296-13-9. Pack Sizes: 5 mg. Product ID: HY-D2264. | |
| Caffeoyltryptophan | Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC 50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase , linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes [1]. Uses: Scientific research. Group: Natural products. CAS No. 109163-69-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N10002. | |
| Caficrestat | Caficrestat (Aldose reductase-IN-1) is a inhibitor of aldose reductase with IC 50 of 28.9 pM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Aldose reductase-IN-1; AT-001. CAS No. 1355612-71-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18967. | |
| Caftaric acid | Caftaric acid is a natural compound. Uses: Scientific research. Group: Natural products. Alternative Names: trans-Caftaric acid. CAS No. 67879-58-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-N0321. | |
| Cagrilintide | Cagrilintide is an investigational novel long-acting acylated amylin analogue, acts as nonselective amylin receptors (AMYR) and calcitonin G protein-coupled receptor (CTR) agonist. Cagrilintide induces significant weight loss and reduces food intake. Cagrilintide has the potential for the research of obesity [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 1415456-99-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3462. | |
| CAL-130 Hydrochloride | CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC 50 s of 1.3 and 6.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431697-78-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16122B. | |
| Calcein | Calcein is a fluorescent dye and self-quenching probe, used as an indicator of lipid vesicle leakage, and also as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. Calcein can also be used as a model drug for evaluating efficiency and bioavailability of drug delivery systems [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Fluorexon. CAS No. 1461-15-0. Pack Sizes: 100 mg. Product ID: HY-D0040. | |
| Calcein-AM | Calcein AM, has cell membrane permeability and can easily enter the cell. Calcein AM has no fluorescence and is hydrolyzed by endogenous esterase in the cell to produce polar molecule Calcein (Calcein), which has strong negative charge and cannot permeate the cell membrane. Calcein can emit strong green fluorescence, so it is often used with Propidium Iodide for cell viability/virulence detection, excitation/emission wavelength: 494/515 nm [1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Calcein acetoxymethyl ester. CAS No. 148504-34-1. Pack Sizes: 1 mg. Product ID: HY-D0041. | |
| Calcein Blue | Calcein Blue, a membrane-impermeant fluorescent dye, is a coumarin derivative that contains an iminodiacetic acid structure. Calcein Blue is also a metallofluorochromic indicator [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 54375-47-2. Pack Sizes: 10 mM * 1 mL; 25 mg. Product ID: HY-101887. | |
| Calcein Blue AM | Calcein Blue AM is a cellular dye agent [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 168482-84-6. Pack Sizes: 1 mg (2.15 mM * 1 mL in DMSO). Product ID: HY-124298. | |
| Calcifediol | Calcifediol (25-hydroxy Vitamin D3) is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 25-hydroxy Vitamin D3. CAS No. 19356-17-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32351. | |
| Calcifediol monohydrate | Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), is an effective VDR ligand and VD supplement. Calcifediol is a prohormone of the vitamin D endocrine system (VDES) and is hydroxylated in the liver to produce the active form, calcitriol. Calcifediol can rapidly increase serum VD levels [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: 25-hydroxy Vitamin D3 monohydrate. CAS No. 63283-36-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-32351A. | |
| Calcipotriol | Calcipotriol is a synthetic VitD 3 analogue with a high affinity for the vitamin D receptor. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MC 903; Calcipotriene. CAS No. 112965-21-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10001. | |
| Calcipotriol monohydrate | Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor. Uses: Scientific research. Group: Signaling pathways. CAS No. 147657-22-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10001A. | |
| Calcitonin gene-related peptide free acid | Calcitonin gene-related peptide (CGRP) free acid is the deamidated form of α-CGRP(human) (HY-P1071). Calcitonin gene-related peptide can be used to study the effect of C-terminal amidation on CGRP [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: CGRP free acid. CAS No. 83652-28-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4058. | |
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